Varicella in the fetus and newborn SEMINARS IN FETAL & NEONATAL MEDICINE Smith, C. K., Arvin, A. M. 2009; 14 (4): 209-217


Varicella (chickenpox) in pregnancy is unusual because most women of childbearing age are immune. It can, however, cause significant morbidity for the pregnant woman and in rare cases cause congenital varicella syndrome. The incidence of congenital varicella syndrome after maternal varicella during the first two trimesters is <1% across multiple cohort studies. Maternal infection in the third trimester is not associated with congenital varicella syndrome, but the infant may develop herpes zoster during the first one or two years. Maternal infection just before or after delivery presents a high risk for disseminated varicella in the infant. Serious infection can be prevented with passive antibody prophylaxis and antiviral therapy. Maternal herpes zoster does not result in adverse fetal or neonatal outcomes.

View details for DOI 10.1016/j.siny.2008.11.008

View details for Web of Science ID 000267631400006

View details for PubMedID 19097954