Ash A. Alizadeh, MD/PhD

Medical oncologist

Lymphoma specialist

Lymphoma Program

  • 875 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
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Professional Education

Board Certification: Medical Oncology, American Board of Internal Medicine (2009)

Fellowship: Stanford University School of Medicine (2009) CA

Residency: Stanford University School of Medicine - Stem Cell Institute Dr Weissman's Laboratory (2006) CA

Internship: Stanford University School of Medicine - Stem Cell Institute Dr Weissman's Laboratory (2005) CA

Medical Education: Stanford university School of Medicine (2003) CA

Board Certification: Hematology, American Board of Internal Medicine (2009)

Board Certification, American Board of Internal Medicine, Hematology (2009)

Board Certification, American Board of Internal Medicine, Medical Oncology (2009)

Board Certification: Internal Medicine, American Board of Internal Medicine (2008)

MD, Stanford university School of Medicine, Medicine (2003)

PhD, Stanford university School of Medicine, Biophysics/Dept of Biochemistry (2003)

B.S., UCLA, Biochemistry (1994)

Honors & Awards

Doris Duke Clinical Scientist Development Award, Stanford University (2011)

Bent & Janet Cardan Oncology Research Fellow, Stanford University (2010)

Josephine Q. Berry Faculty Scholar in Cancer Research, Stanford University (2010)

Clinical Investigator Program: Fellow Award, Stanford University Medical Center (2004-2010)

Leukemia & Lymphoma Society Special Fellow in Clinical Research, Stanford University (2010)

Franklin G. Ebaugh, Jr. Award for Outstanding Research, Dept of Medicine, Stanford (2004-2005)

Sandler Fellow Award, UCSF (2003-2004)

Medical Scientist Training Program Award, NIH (1996-2003)

Research Scholar Award for Outstanding Research, HHMI (1998)

Intramural Research Award, NIH/NCI (1997 – 1998)

Research Scholar Award, HHMI-NIH (1996 – 1998)

NIH Research Fellow Award, NIH/NCI (6/1995)

Magna cum laude, College & Departmental Honors, UCLA (6/1993)

Administrative Appointments

Steering Committee Member & Mentor, Stanford Computational & Systems Immunology, 2012

Admissions Panel, Medical Scientist Training Program, Stanford University, 2011

Chair, Seminar Committee, Stanford Immunology Program, 2011

Association of a Leukemic Stem Cell Gene Expression Signature With Clinical Outcomes in Acute Myeloid Leukemia
Gentles, A. J., Plevritis, S. K., Majeti, R., & Alizadeh, A. A. (2010). Association of a Leukemic Stem Cell Gene Expression Signature With Clinical Outcomes in Acute Myeloid Leukemia. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 304(24), 2706-2715.

Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma
Chao MP* Alizadeh AA* (contributed equally), Tang CZ, Mykebust JH, Varghese B, Jan M, & Majeti R. (2010). Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma. Cell, 142(5).

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells
Majeti, R., Chao, M. P., Alizadeh, A. A., Pang, W. W., Jaiswal, S., & Weissman, I. L. (2009). CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells. CELL, 138(2), 286-299.

Molecular Outcome Prediction in Diffuse Large-B-Cell Lymphoma
Alizadeh, A. A., Gentles, A. J., Lossos, I. S., & Levy, R. (2009). Molecular Outcome Prediction in Diffuse Large-B-Cell Lymphoma. NEW ENGLAND JOURNAL OF MEDICINE, 360(26), 2794-2795.

SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data
Diehn, M., Sherlock, G., Binkley, G., Jin, H., Matese, J. C., & Alizadeh, A. A. (2003). SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. NUCLEIC ACIDS RESEARCH, 31(1), 219-223.

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., & Staudt, L. M. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. NATURE, 403(6769), 503-511.

The lymphochip: A specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes
Alizadeh, A., Eisen, M., Davis, R. E., Ma, C., Sabet, H., & Staudt, L. M. (1999). The lymphochip: A specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 64, 71-78.

Identification of gene microarray expression profiles in patients with chronic graft-versus-host disease following allogeneic hematopoietic cell transplantation.
Kohrt, H. E., Tian, L., Li, L., Alizadeh, A. A., Hsieh, S., & Lowsky, R. (2013). Identification of gene microarray expression profiles in patients with chronic graft-versus-host disease following allogeneic hematopoietic cell transplantation. Clinical immunology , 148(1), 124-135.

Utility in prognostic value added by molecular profiles for diffuse large B-cell lymphoma.
Gentles, A. J., & Alizadeh, A. A. (2013). Utility in prognostic value added by molecular profiles for diffuse large B-cell lymphoma. Blood, 121(15), 3052-3054.

Rituximab use and survival after diffuse large B-cell or follicular lymphoma: a population-based study
Keegan, T. Hm., Moy, L. M., Foran, J. M., Alizadeh, A. A., Chang, E. T., & Glaser, S. L. (2013). Rituximab use and survival after diffuse large B-cell or follicular lymphoma: a population-based study. LEUKEMIA & LYMPHOMA, 54(4), 743-751.

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma.
Green, M. R., Gentles, A. J., Nair, R. V., Irish, J. M., Kihira, S., & Alizadeh, A. A. (2013). Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood, 121(9), 1604-1611.

High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells.
Myklebust, J. H., Irish, J. M., Brody, J., Czerwinski, D. K., Houot, R., & Levy, R. (2013). High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells. Blood, 121(8), 1367-1376.

Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation
Romero-Camarero, I., Jiang, X., Natkunam, Y., Lu, X., Vicente-Duenas, C., & Lossos, I. S. (2013). Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. NATURE COMMUNICATIONS, 4.

Hierarchy in Somatic Mutations Arising During Genomic Evolution and Progression of Follicular Lymphoma
Green, M. R., Gentles, A. J., Nair, R. V., Irish, J. M., Levy, R., & Alizadeh, A. A. (2012). Hierarchy in Somatic Mutations Arising During Genomic Evolution and Progression of Follicular Lymphoma. BLOOD, 120(21).

Systematic Deconvolution of Hematolymphoid Tumor Transcriptomes Reveals Infiltrating Immune Cell Signatures Related to Survival
Newman, A. M., Gentles, A. J., Plevritis, S. K., & Alizadeh, A. A. (2012). Systematic Deconvolution of Hematolymphoid Tumor Transcriptomes Reveals Infiltrating Immune Cell Signatures Related to Survival. BLOOD, 120(21).

Genome-Wide Characterization of Human Hematopoietic Progenitor Cell Heterogeneity by Expression Profiling of Single Cells: A Pilot Study
Liu, C. L., Dai, B., Newman, A. M., Majeti, R., & Alizadeh, A. A. (2012). Genome-Wide Characterization of Human Hematopoietic Progenitor Cell Heterogeneity by Expression Profiling of Single Cells: A Pilot Study. BLOOD, 120(21).

Identification of Candidate Transcriptional Biomarkers Associated with Chronic Graft-Versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation
Kohrt, H. E., Tian, L., Li, L., Alizadeh, A. A., Hsieh, S., & Lowsky, R. (2012). Identification of Candidate Transcriptional Biomarkers Associated with Chronic Graft-Versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation. BLOOD, 120(21).

Targeting B-Cell Lymphoma with Idiotype-Specific Peptibodies: Toward a Personalized and Tumor-Specific Therapy
Torchia, J. A., Ng, P. P., Chen, H., Kohrt, H. E., Marabelle, A., & Levy, R. (2012). Targeting B-Cell Lymphoma with Idiotype-Specific Peptibodies: Toward a Personalized and Tumor-Specific Therapy. BLOOD, 120(21).

Self-antigen recognition by follicular lymphoma B-cell receptors
Sachen, K. L., Strohman, M. J., Singletary, J., Alizadeh, A. A., Kattah, N. H., & Levy, R. (2012). Self-antigen recognition by follicular lymphoma B-cell receptors. BLOOD, 120(20), 4182-4190.

Cell-free DNA as a Biomarker of Residual Disease Following Radiation Therapy for Non-small Cell Lung Cancer
Bratman, S. V., Eclov, N. C., Modlin, L. A., Neal, J., Loo, B. W., & Diehn, M. (2012). Cell-free DNA as a Biomarker of Residual Disease Following Radiation Therapy for Non-small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(3), S713-S713.

Role of Smad Proteins in Resistance to BMP-Induced Growth Inhibition in B-Cell Lymphoma
Huse, K., Bakkebo, M., Walchli, S., Oksvold, M. P., Hilden, V. I., & Myklebust, J. H. (2012). Role of Smad Proteins in Resistance to BMP-Induced Growth Inhibition in B-Cell Lymphoma. PLOS ONE, 7(10).

CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas Diagnostic and Therapeutic Implications
Anderson, M. W., Zhao, S., Freud, A. G., Czerwinski, D. K., Kohrt, H., & Natkunam, Y. (2012). CD137 Is Expressed in Follicular Dendritic Cell Tumors and in Classical Hodgkin and T-Cell Lymphomas Diagnostic and Therapeutic Implications. AMERICAN JOURNAL OF PATHOLOGY, 181(3), 795-803.

The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses
Pachynski, R. K., Zabel, B. A., Kohrt, H. E., Tejeda, N. M., Monnier, J., & Butcher, E. C. (2012). The chemoattractant chemerin suppresses melanoma by recruiting natural killer cell antitumor defenses. JOURNAL OF EXPERIMENTAL MEDICINE, 209(8), 1427-1435.

A retrospective study evaluating the efficacy and safety of bendamustine in the treatment of mantle cell lymphoma
Warsch, S., Hosein, P. J., Maeda, L. S., Alizadeh, A. A., & Lossos, I. S. (2012). A retrospective study evaluating the efficacy and safety of bendamustine in the treatment of mantle cell lymphoma. LEUKEMIA & LYMPHOMA, 53(7), 1299-1305.

The chemoattractant chemerin as a natural tumor suppressive cytokine.
Pachynski, R. K., Zabel, B., Tejeda, N., Monnier, J., Holzer, A. K., & Butcher, E. (2012). The chemoattractant chemerin as a natural tumor suppressive cytokine. JOURNAL OF CLINICAL ONCOLOGY, 30(15).

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors
Willingham, S. B., Volkmer, J.-P., Gentles, A. J., Sahoo, D., Dalerba, P., & Weissman, I. L. (2012). The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(17), 6662-6667.

First Isolation of Cryptococcus uzbekistanensis from an Immunocompromised Patient with Lymphoma
Powel, M. S., Alizadeh, A. A., Budvytiene, I., Schaenman, J. M., & Banaei, N. (2012). First Isolation of Cryptococcus uzbekistanensis from an Immunocompromised Patient with Lymphoma. JOURNAL OF CLINICAL MICROBIOLOGY, 50(3), 1125-1127.

Three differentiation states risk-stratify bladder cancer into distinct subtypes
Volkmer, J.-P., Sahoo, D., Chin, R. K., Ho, P. L., Tang, C., & Chan, K. S. (2012). Three differentiation states risk-stratify bladder cancer into distinct subtypes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(6), 2078-2083.

Treatment advances have not improved the early death rate in acute promyelocytic leukemia
McClellan, J. S., Kohrt, H. E., Coutre, S., Gotlib, J. R., Majeti, R., & Medeiros, B. C. (2012). Treatment advances have not improved the early death rate in acute promyelocytic leukemia. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 97(1), 133-136.

Correction: Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.
Liu, C. L., Tangsombatvisit, S., Rosenberg, J. M., Mandelbaum, G., Gillespie, E. C., & Utz, P. J. (2012). Correction: Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. Arthritis research & therapy, 14(4), 403.

Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies
Liu, C. L., Tangsombatvisit, S., Rosenberg, J. M., Mandelbaum, G., Gillespie, E. C., & Utz, P. J. (2012). Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies. ARTHRITIS RESEARCH & THERAPY, 14(1).

Immunotransplant for Mantle Cell Lymphoma: Phase I/II Study Preliminary Results
Brody, J. D., Czerwinski, D. K., Carlton, V., Moorhead, M., Zheng, J., & Levy, R. (2011). Immunotransplant for Mantle Cell Lymphoma: Phase I/II Study Preliminary Results. BLOOD, 118(21), 1323-1323.

A few good genes Simple, biologically motivated signatures for cancer prognosis
Gentles, A. J., & Alizadeh, A. A. (2011). A few good genes Simple, biologically motivated signatures for cancer prognosis. CELL CYCLE, 10(21), 3615-3616.

A proteomic approach for the identification of novel lysine methyltransferase substrates
Levy, D., Liu, C. L., Yang, Z., Newman, A. M., Alizadeh, A. A., & Gozani, O. (2011). A proteomic approach for the identification of novel lysine methyltransferase substrates. EPIGENETICS & CHROMATIN, 4.

Utility of positron emission tomography scans in mantle cell lymphoma
Hosein, P. J., Pastorini, V. H., Paes, F. M., Eber, D., Chapman, J. R., & Lossos, I. S. (2011). Utility of positron emission tomography scans in mantle cell lymphoma. AMERICAN JOURNAL OF HEMATOLOGY, 86(10), 841-845.

Impact of TET2 mutations on mRNA expression and clinical outcomes in MDS patients treated with DNA methyltransferase inhibitors
Pollyea, D. A., Raval, A., Kusler, B., Gotlib, J. R., Alizadeh, A. A., & Mitchell, B. S. (2011). Impact of TET2 mutations on mRNA expression and clinical outcomes in MDS patients treated with DNA methyltransferase inhibitors. HEMATOLOGICAL ONCOLOGY, 29(3), 157-160.

Surprise! HSC Are Aberrant in Chronic Lymphocytic Leukemia
Alizadeh, A. A., & Majeti, R. (2011). Surprise! HSC Are Aberrant in Chronic Lymphocytic Leukemia. CANCER CELL, 20(2), 135-136.

Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment
Alizadeh, A. A., Gentles, A. J., Alencar, A. J., Liu, C. L., Kohrt, H. E., & Levy, R. (2011). Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment. BLOOD, 118(5), 1350-1358.

Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker
Jan, M., Chao, M. P., Cha, A. C., Alizadeh, A. A., Gentles, A. J., & Majeti, R. (2011). Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(12), 5009-5014.

CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies
Kohrt, H. E., Houot, R., Goldstein, M. J., Weiskopf, K., Alizadeh, A. A., & Levy, R. (2011). CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. BLOOD, 117(8), 2423-2432.

Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia
Chao, M. P., Alizadeh, A. A., Tang, C., Jan, M., Weissman-Tsukamoto, R., & Majeti, R. (2011). Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia. CANCER RESEARCH, 71(4), 1374-1384.

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
Chao, M. P., Jaiswal, S., Weissman-Tsukamoto, R., Alizadeh, A. A., Gentles, A. J., & Weissman, I. L. (2010). Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47. SCIENCE TRANSLATIONAL MEDICINE, 2(63).

NF-kappa B Signaling In Response to CpG Stratifies Mantle Cell Lymphoma Patient Outcome
Myklebust, J. H., Irish, J. M., Brody, J., Alizadeh, A. A., Czerwinski, D., & Levy, R. (2010). NF-kappa B Signaling In Response to CpG Stratifies Mantle Cell Lymphoma Patient Outcome. BLOOD, 116(21), 67-68.

Prediction of Survival In Diffuse Large B-Cell Lymphoma Based On the Expression of Two Genes Reflecting Tumor and Microenvironment
Alizadeh, A. A., Gentles, A. J., Alencar, A. J., Kohrt, H. E., Houot, R., & Levy, R. (2010). Prediction of Survival In Diffuse Large B-Cell Lymphoma Based On the Expression of Two Genes Reflecting Tumor and Microenvironment. BLOOD, 116(21), 836-837.

Noninvasive Prediction of Graft-Verus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation by Gene Expression Profiling
Kohrt, H. E., Li, L., Alizadeh, A. A., Goldstein, M. J., Strober, S., & Lowsky, R. (2010). Noninvasive Prediction of Graft-Verus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation by Gene Expression Profiling. BLOOD, 116(21), 393-394.

Self-Antigen Recognition by the B Cell Receptors of Follicular Lymphoma
Layn, K., Alizadeh, A. A., Kattah, N., Levy, S., & Levy, R. (2010). Self-Antigen Recognition by the B Cell Receptors of Follicular Lymphoma. BLOOD, 116(21), 1678-1679.

Clinical and Pathological Features of Non-Hodgkin Lymphomas Harboring Concurrent t(14;18) and 8q24 Anomalies
Alizadeh, A. A., Anderson, M., Kohrt, H. E., Shyam, R. M., Bangs, C. D., & Levy, R. (2010). Clinical and Pathological Features of Non-Hodgkin Lymphomas Harboring Concurrent t(14;18) and 8q24 Anomalies. BLOOD, 116(21), 1291-1292.

Second-line mitoxantrone, etoposide, and cytarabine for acute myeloid leukemia: A single-center experience
Kohrt, H. E., Patel, S., Ho, M., Owen, T., Pollyea, D. A., & Medeiros, B. C. (2010). Second-line mitoxantrone, etoposide, and cytarabine for acute myeloid leukemia: A single-center experience. AMERICAN JOURNAL OF HEMATOLOGY, 85(11), 877-881.

B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
Irish, J. M., Myklebust, J. H., Alizadeh, A. A., Houot, R., Sharman, J. P., & Levy, R. (2010). B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(29), 12747-12754.

Expression profiles of adult T-cell leukemia-lymphoma and associations with clinical responses to zidovudine and interferon alpha
Alizadeh, A. A., Bohen, S. P., Lossos, C., Martinez-Climent, J. A., Ramos, J. C., & Lossos, I. S. (2010). Expression profiles of adult T-cell leukemia-lymphoma and associations with clinical responses to zidovudine and interferon alpha. LEUKEMIA & LYMPHOMA, 51(7), 1200-1216.

Immunophenotypic features of acute myeloid leukemia with inv(3)(q21q26.2)/t(3;3)(q21;q26.2)
Medeiros, B. C., Kohrt, H. E., Arber, D. A., Bangs, C. D., Cherry, A. M., & Alizadeh, A. A. (2010). Immunophenotypic features of acute myeloid leukemia with inv(3)(q21q26.2)/t(3;3)(q21;q26.2). LEUKEMIA RESEARCH, 34(5), 594-597.

Noninvasive Prediction of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation by Gene Expression Profiling.
Li, L., Kohrt, H., Heish, S., Alizadeh, A., Laport, G., & Sarwal, M. (2010). Noninvasive Prediction of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantation by Gene Expression Profiling. AMERICAN JOURNAL OF TRANSPLANTATION, 10, 483-483.

Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS)
Kohrt HE, Patel S, Ho M, Owen T, Majeti R, & Alizadeh AA. (2010). Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS). Blood (e-Letter), 113(1).

Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Xenografts
Chao, M. P., Alizadeh, A. A., Tang, C. Z., Myklebust, J. H., Varghese, B., & Majeti, R. (2009). Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Xenografts. BLOOD, 114(22), 1063-1064.

Gene Expression Signature of Host Immune Response Is Predictive of Follicular Lymphoma Patient Survival in Independent Cohorts, and Correlates with Transformation to Diffuse Large B-Cell Lymphoma.
Alizadeh, A. A., Gentles, A. J., Plevritis, S. K., & Levy, R. (2009). Gene Expression Signature of Host Immune Response Is Predictive of Follicular Lymphoma Patient Survival in Independent Cohorts, and Correlates with Transformation to Diffuse Large B-Cell Lymphoma. BLOOD, 114(22), 1153-1153.

Prediction of Survival in Diffuse Large B-Cell Lymphoma Based On the Expression of Two Genes: Integration of Tumor and Microenvironment Contributions
Alizadeh, A. A., Gentles, A. J., Alencar, A. J., Kohrt, H. E., Houot, R., & Levy, R. (2009). Prediction of Survival in Diffuse Large B-Cell Lymphoma Based On the Expression of Two Genes: Integration of Tumor and Microenvironment Contributions. BLOOD, 114(22), 258-258.

Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS).
Kohrt, H. E., Patel, S., Ho, M., Owen, T., Majeti, R., & Alizadeh, A. A. (2009). Is Time of the Essence in Adult Acute Myeloid Leukemia (AML)? Time to Blast Clearance and Time to Induction Therapy Fail to Predict Overall Survival (OS). BLOOD, 114(22), 646-647.

Early Mortality in Acute Promyelocytic Leukemia May Be Higher Than Previously Reported.
Alizadeh, A. A., McClellan, J. S., Gotlib, J. R., Coutre, S., Majeti, R., & Medeiros, B. C. (2009). Early Mortality in Acute Promyelocytic Leukemia May Be Higher Than Previously Reported. BLOOD, 114(22), 420-421.

A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling
Myklebust, J. H., Irish, J. M., Houot, R., Brody, J., Czerwinski, D. K., & Levy, R. (2009). A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling. BLOOD, 114(22), 316-316.

Therapeutic Potential of Anti-CD137 Antibody in Lymphoma
Houot, R., Goldstein, M. J., Kohrt, H. E., Myklebust, J. H., Alizadeh, A. A., & Levy, R. (2009). Therapeutic Potential of Anti-CD137 Antibody in Lymphoma. BLOOD, 114(22), 301-302.

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T-reg depletion
Houot, R., Goldstein, M. J., Kohrt, H. E., Myklebust, J. H., Alizadeh, A. A., & Levy, R. (2009). Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T-reg depletion. BLOOD, 114(16), 3431-3438.

CD47 IS AN ADVERSE PROGNOSTIC FACTOR IN NON-HODGKIN LYMPHOMA AND A THERAPEUTIC ANTIBODY TARGET THAT SYNERGIZES WITH RITUXIMAB
Chao, M. P., Alizadeh, A., Tang, C. Z., Jan, M., Levy, R., & Weissman, I. L. (2009). CD47 IS AN ADVERSE PROGNOSTIC FACTOR IN NON-HODGKIN LYMPHOMA AND A THERAPEUTIC ANTIBODY TARGET THAT SYNERGIZES WITH RITUXIMAB. EXPERIMENTAL HEMATOLOGY, 37(9), S8-S9.

A pluripotency signature predicts histological transformation and influences survival in follicular lymphoma patients
Gentles AJ**, Alizadeh AA** (contributed equally), Lee S, Myklebust JH, Shachaf CM, & Plevritis SK. (2009). A pluripotency signature predicts histological transformation and influences survival in follicular lymphoma patients. Blood.

Evaluation and management of angioimmunoblastic T-cell lymphoma: a review of current approaches and future strategies.
Alizadeh, A. A., & Advani, R. H. (2008). Evaluation and management of angioimmunoblastic T-cell lymphoma: a review of current approaches and future strategies. Clinical advances in hematology & oncology : H&O, 6(12), 899-909.

CD47 Is An Independent Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells
Majeti, R., Chao, M. P., Alizadeh, A. A., Pang, W. W., & Weissman, I. L. (2008). CD47 Is An Independent Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells. BLOOD, 112(11), 284-284.

LMO2 Protein Expression Predicts Survival in Patients with Diffuse Large B-Cell Lymphoma Treated with Immunochemotherapy (RCHOP): A Multicenter Validation Study.
Advani, R., Talreja, N., Tibshirani, R., Zhao, S., Alizadeh, A., & Natkunam, Y. (2008). LMO2 Protein Expression Predicts Survival in Patients with Diffuse Large B-Cell Lymphoma Treated with Immunochemotherapy (RCHOP): A Multicenter Validation Study. BLOOD, 112(11), 1291-1291.

Double trouble in follicular lymphoma: A rare and unusual synergy of oncogenes in the germinal center
Alizadeh, A. A., & Lossos, I. S. (2008). Double trouble in follicular lymphoma: A rare and unusual synergy of oncogenes in the germinal center. LEUKEMIA & LYMPHOMA, 49(3), 377-380.

Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray
Chiu, C. Y., Alizadeh, A. A., Rouskin, S., Merker, J. D., Yeh, E., & DeRisi, J. L. (2007). Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray. JOURNAL OF CLINICAL MICROBIOLOGY, 45(7), 2340-2343.

Cell-type specific gene expression profiles of leukocytes in human peripheral blood
Palmer, C., Diehn, M., Alizadeh, A. A., & Brown, P. O. (2006). Cell-type specific gene expression profiles of leukocytes in human peripheral blood. BMC GENOMICS, 7.

Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas
Lu, X. Q., Nechushtan, H., Ding, F. Y., Rosado, M. F., Singal, R., & Lossos, I. S. (2005). Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas. BLOOD, 105(7), 2924-2932.

AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity
Lossos, I. S., Levy, R., & Alizadeh, A. A. (2004). AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity. LEUKEMIA, 18(11), 1775-1779.

Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response
Rosenwald, A., Chuang, E. Y., Davis, R. E., Wiestner, A., Alizadeh, A. A., & Staudt, L. M. (2004). Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response. BLOOD, 104(5), 1428-1434.

Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes
Lossos, I. S., Czerwinski, D. K., Alizadeh, A. A., Wechser, M. A., Tibshirani, R., & Levy, R. (2004). Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. NEW ENGLAND JOURNAL OF MEDICINE, 350(18), 1828-1837.

Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.
Chang, H. Y., Sneddon, J. B., Alizadeh, A. A., Sood, R., West, R. B., & Brown, P. O. (2004). Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. PLoS biology, 2(2), E7-?.

Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock
Pathan, N., Hemingway, C. A., Alizadeh, A. A., Stephens, A. C., Boldrick, J. C., & Levin, M. (2004). Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock. LANCET, 363(9404), 203-209.

T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression
Roose, J. P., Diehn, M., Tomlinson, M. G., Lin, J., Alizadeh, A. A., & Weiss, A. (2003). T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLOS BIOLOGY, 1(2), 271-287.

T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression.
Roose, J. P., Diehn, M., Tomlinson, M. G., Lin, J., Alizadeh, A. A., & Weiss, A. (2003). T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. PLoS biology, 1(2), E53-?.

Rheumatoid arthritis is a heterogeneous disease - Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues
Kraan, T. Ctmv., van Gaalen, F. A., Kasperkovitz, P. V., Verbeet, N. L., Smeets, T. Jm., & Verweij, C. L. (2003). Rheumatoid arthritis is a heterogeneous disease - Evidence for differences in the activation of the STAT-1 pathway between rheumatoid tissues. ARTHRITIS AND RHEUMATISM, 48(8), 2132-2145.

Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations
Martinez-Climent, J. A., Alizadeh, A. A., Segraves, R., Blesa, D., Rubio-Moscardo, F., & Lossos, I. S. (2003). Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterations. BLOOD, 101(8), 3109-3117.

Individuality and variation in gene expression patterns in human blood
Whitney, A. R., Diehn, M., Popper, S. J., Alizadeh, A. A., Boldrick, J. C., & Brown, P. O. (2003). Individuality and variation in gene expression patterns in human blood. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(4), 1896-1901.

HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma
Lossos, I. S., Alizadeh, A. A., Rajapaksa, R., Tibshirani, R., & Levy, R. (2003). HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma. BLOOD, 101(2), 433-440.

Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling
Sarwal M, Chen X, Chua MS, Kambham N, Hsieh SC, & Brown PO. (2003). Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N Engl J Med, 349(2).

Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays
Liu, C. L., Prapong, W., Natkunam, Y., Alizadeh, A., Montgomery, K., & van de Rijn, M. (2002). Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. AMERICAN JOURNAL OF PATHOLOGY, 161(5), 1557-1565.

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
Diehn, M., Alizadeh, A. A., Rando, O. J., Liu, C. L., Stankunas, K., & Brown, P. O. (2002). Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(18), 11796-11801.

Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes
Lossos, I. S., Alizadeh, A. A., Diehn, M., Warnke, R., Thorstenson, Y., & Levy, R. (2002). Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(13), 8886-8891.

The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile
Huang, J. Z., Sanger, W. G., Greiner, T. C., Staudt, L. M., Weisenburger, D. D., & Chan, W. C. (2002). The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile. BLOOD, 99(7), 2285-2290.

In vivo regulation of human skeletal muscle gene expression by thyroid hormone
Clement, K., Viguerie, N., Diehn, M., Alizadeh, A., Barbe, P., & Langin, D. (2002). In vivo regulation of human skeletal muscle gene expression by thyroid hormone. GENOME RESEARCH, 12(2), 281-291.

Stereotyped and specific gene expression programs in human innate immune responses to bacteria
Boldrick, J. C., Alizadeh, A. A., Diehn, M., Dudoit, S., Liu, C. L., & Relman, D. A. (2002). Stereotyped and specific gene expression programs in human innate immune responses to bacteria. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(2), 972-977.

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
Rosenwald, A., Alizadeh, A. A., Widhopf, G., Simon, R., Davis, R. E., & Staudt, L. M. (2001). Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. JOURNAL OF EXPERIMENTAL MEDICINE, 194(11), 1639-1647.

Towards a novel classification of human malignancies based on gene expression patterns
Alizadeh, A. A., Ross, D. T., Perou, C. M., & van de Rijn, M. (2001). Towards a novel classification of human malignancies based on gene expression patterns. JOURNAL OF PATHOLOGY, 195(1), 41-52.

Genomic analysis of renal allograft dysfunction using cDNA microarrays
Sarwal, M., Chang, S., Barry, C., Chen, X., Alizadeh, A., & BROWN, P. (2001). Genomic analysis of renal allograft dysfunction using cDNA microarrays. TRANSPLANTATION PROCEEDINGS, 33(1-2), 297-298.

Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas
Lossos, I. S., Alizadeh, A. A., Eisen, M. B., Chan, W. C., Brown, P. O., & Levy, R. (2000). Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(18), 10209-10213.

Exploring gene expression signatures of host responses to infection
Boldrick, J. C., Belcher, C. E., Alizadeh, A. A., Liu, C. L., Diehn, M., & Relman, D. A. (2000). Exploring gene expression signatures of host responses to infection. CLINICAL INFECTIOUS DISEASES, 31(1), 218-218.

Examining the living genome in health and disease with DNA microarrays
Diehn, M., Alizadeh, A. A., & Brown, P. O. (2000). Examining the living genome in health and disease with DNA microarrays. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 283(17), 2298-2299.

Genomic-scale gene expression profiling of normal and malignant immune cells
Alizadeh, A. A., & Staudt, L. M. (2000). Genomic-scale gene expression profiling of normal and malignant immune cells. CURRENT OPINION IN IMMUNOLOGY, 12(2), 219-225.

'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns.
Hastie, T., Tibshirani, R., Eisen, M. B., Alizadeh, A., Levy, R., & BROWN, P. (2000). 'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns. Genome biology, 1(2), RESEARCH0003-?.

Gene expression in large B-cell lymphoma using cDNA microarray technology.
Chan, W. C., Alizadeh, A., Eisen, M., Davis, R. E., Ma, C., & Staudt, L. M. (1999). Gene expression in large B-cell lymphoma using cDNA microarray technology. BLOOD, 94(10), 698A-698A.

Genome-wide analysis of DNA copy-number changes using cDNA microarrays
Pollack, J. R., Perou, C. M., Alizadeh, A. A., Eisen, M. B., Pergamenschikov, A., & Brown, P. O. (1999). Genome-wide analysis of DNA copy-number changes using cDNA microarrays. NATURE GENETICS, 23(1), 41-46.

Probing lymphocyte biology by genomic-scale gene expression analysis
Alizadeh, A., Eisen, M., Botstein, D., Brown, P. O., & Staudt, L. M. (1998). Probing lymphocyte biology by genomic-scale gene expression analysis. JOURNAL OF CLINICAL IMMUNOLOGY, 18(6), 373-379.