Manuel Amieva

Professional Education

Fellowship: Stanford University School of Medicine (2004) CA

Residency: Stanford University School of Medicine (1999) CA

Internship: Stanford University School of Medicine (1998) CA

Board Certification: Pediatric Infectious Disease, American Board of Pediatrics (2005)

Medical Education: Stanford University School of Medicine (1997) CA

Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans
Noto, J. M., Gaddy, J. A., Lee, J. Y., Piazuelo, M. B., Friedman, D. B., & Peek, R. M. (2013). Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans. JOURNAL OF CLINICAL INVESTIGATION, 123(1), 479-492.

ChePep Controls Helicobacter pylori Infection of the Gastric Glands and Chemotaxis in the Epsilonproteobacteria
Howitt, M. R., Lee, J. Y., Lertsethtakarn, P., Vogelmann, R., Joubert, L.-M., & Amieva, M. R. (2011). ChePep Controls Helicobacter pylori Infection of the Gastric Glands and Chemotaxis in the Epsilonproteobacteria. MBIO, 2(4).

Helicobacter pylori Perturbs Iron Trafficking in the Epithelium to Grow on the Cell Surface
Tan, S., Noto, J. M., Romero-Gallo, J., Peek, R. M., & Amieva, M. R. (2011). Helicobacter pylori Perturbs Iron Trafficking in the Epithelium to Grow on the Cell Surface. PLOS PATHOGENS, 7(5).

Listeria monocytogenes Internalin B Activates Junctional Endocytosis to Accelerate Intestinal Invasion
Pentecost, M., Kumaran, J., Ghosh, P., & Amieva, M. R. (2010). Listeria monocytogenes Internalin B Activates Junctional Endocytosis to Accelerate Intestinal Invasion. PLOS PATHOGENS, 6(5).

Helicobacter pylori Usurps Cell Polarity to Turn the Cell Surface into a Replicative Niche
Tan, S., Tompkins, L. S., & Amieva, M. R. (2009). Helicobacter pylori Usurps Cell Polarity to Turn the Cell Surface into a Replicative Niche. PLOS PATHOGENS, 5(5).

Host-bacterial interactions in Helicobacter pylori infection
Amieva, M. R., & El-Omar, E. M. (2008). Host-bacterial interactions in Helicobacter pylori infection. GASTROENTEROLOGY, 134(1), 306-323.

Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion
Pentecost, M., Otto, G., Theriot, J. A., & Amieva, M. R. (2006). Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion. PLOS PATHOGENS, 2(1), 29-40.

Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells
Bagnoli, F., Buti, L., Tompkins, L., Covacci, A., & Amieva, M. R. (2005). Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(45), 16339-16344.

Important bacterial gastrointestinal pathogens in children: A pathogenesis perspective
Amieva, M. R. (2005). Important bacterial gastrointestinal pathogens in children: A pathogenesis perspective. PEDIATRIC CLINICS OF NORTH AMERICA, 52(3), 749-?.

Breaking into the epithelial apical-junctional complex - news from pathogen hackers
Vogelmann, R., Amieva, M. R., FALKOW, S., & Nelson, W. J. (2004). Breaking into the epithelial apical-junctional complex - news from pathogen hackers. CURRENT OPINION IN CELL BIOLOGY, 16(1), 86-93.

Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA
Amieva, M. R., Vogelmann, R., Covacci, A., Tompkins, L. S., NELSON, W. J., & FALKOW, S. (2003). Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. SCIENCE, 300(5624), 1430-1434.

Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells
Amieva, M. R., Salama, N. R., Tompkins, L. S., & FALKOW, S. (2002). Helicobacter pylori enter and survive within multivesicular vacuoles of epithelial cells. CELLULAR MICROBIOLOGY, 4(10), 677-690.

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
Yan, K. S., Chia, L. A., Li, X., Ootani, A., Su, J., & Kuo, C. J. (2012). The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(2), 466-471.

Tolerance Rather Than Immunity Protects From Helicobacter pylori-Induced Gastric Preneoplasia
Arnold, I. C., Lee, J. Y., Amieva, M. R., Roers, A., Flavell, R. A., & Mueller, A. (2011). Tolerance Rather Than Immunity Protects From Helicobacter pylori-Induced Gastric Preneoplasia. GASTROENTEROLOGY, 140(1), 199-?.

The Complete Genome Sequence of Helicobacter pylori Strain G27
Baltrus, D. A., Amieva, M. R., Covacci, A., Lowe, T. M., Merrell, D. S., & Guillemin, K. (2009). The Complete Genome Sequence of Helicobacter pylori Strain G27. JOURNAL OF BACTERIOLOGY, 191(1), 447-448.

The role of bacterial pathogens in cancer
Vogelmann, R., & Amieva, M. R. (2007). The role of bacterial pathogens in cancer. CURRENT OPINION IN MICROBIOLOGY, 10(1), 76-81.

Helicobacter pylori and gastric cancer: What can be learned by studying the response of gastric epithelial cells to the infection?
Mueller, A., FALKOW, S., & Amieva, M. R. (2005). Helicobacter pylori and gastric cancer: What can be learned by studying the response of gastric epithelial cells to the infection?. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 14(8), 1859-1864.

Jarisch-Herxheimer reaction associated with ciprofloxacin administration for tick-borne relapsing fever
Webster, G., Schiffman, J. D., Dosanjh, A. S., Amieva, M. R., Gans, H. A., & Sectish, T. C. (2002). Jarisch-Herxheimer reaction associated with ciprofloxacin administration for tick-borne relapsing fever. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 21(6), 571-573.

Imaging of dynamic changes of the actin cytoskeleton in microextensions of live NIH3T3 cells with a GFP fusion of the F-actin binding domain of moesin.
Litman, P., Amieva, M. R., & FURTHMAYR, H. (2000). Imaging of dynamic changes of the actin cytoskeleton in microextensions of live NIH3T3 cells with a GFP fusion of the F-actin binding domain of moesin. BMC cell biology, 1, 1-?.

Disruption of dynamic cell surface architecture of NIH3T3 fibroblasts by the N-terminal domains of moesin and ezrin: in vivo imaging with GFP fusion proteins
Amieva, M. R., Litman, P., Huang, L. Q., Ichimaru, E., & Furthmayr, H. (1999). Disruption of dynamic cell surface architecture of NIH3T3 fibroblasts by the N-terminal domains of moesin and ezrin: in vivo imaging with GFP fusion proteins. JOURNAL OF CELL SCIENCE, 112(1), 111-125.

The plasma membrane-actin linking protein, ezrin, is a glomerular epithelial cell marker in glomerulogenesis, in the adult kidney and in glomerular injury
Hugo, C., Nangaku, M., Shankland, S. J., Pichler, R., Gordon, K., & JOHNSON, R. J. (1998). The plasma membrane-actin linking protein, ezrin, is a glomerular epithelial cell marker in glomerulogenesis, in the adult kidney and in glomerular injury. KIDNEY INTERNATIONAL, 54(6), 1934-1944.

Hypoxia increases human keratinocyte motility on connective tissue
O'Toole, E. A., Marinkovich, M. P., Peavey, C. L., Amieva, M. R., FURTHMAYR, H., & Woodley, D. T. (1997). Hypoxia increases human keratinocyte motility on connective tissue. JOURNAL OF CLINICAL INVESTIGATION, 100(11), 2881-2891.

Phosphorylation of T-558 of moesin detected by site-specific antibodies in RAW264.7 macrophages
Nakamura, F., Amieva, M. R., Hirota, C., Mizuno, Y., & FURTHMAYR, H. (1996). Phosphorylation of T-558 of moesin detected by site-specific antibodies in RAW264.7 macrophages. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 226(3), 650-656.

The cytoskeletal linking proteins, moesin and radixin, are upregulated by platelet-derived growth factor, but not basic fibroblast growth factor in experimental mesangial proliferative glomerulonephritis
Hugo, C., Hugo, C., Pichler, R., Gordon, K., Schmidt, R., & JOHNSON, R. J. (1996). The cytoskeletal linking proteins, moesin and radixin, are upregulated by platelet-derived growth factor, but not basic fibroblast growth factor in experimental mesangial proliferative glomerulonephritis. JOURNAL OF CLINICAL INVESTIGATION, 97(11), 2499-2508.

Phosphorylation of threonine 558 in the carboxyl-terminal actin-binding domain of moesin by thrombin activation of human platelets
Nakamura, F., Amieva, M. R., & FURTHMAYR, H. (1995). Phosphorylation of threonine 558 in the carboxyl-terminal actin-binding domain of moesin by thrombin activation of human platelets. JOURNAL OF BIOLOGICAL CHEMISTRY, 270(52), 31377-31385.

SUBCELLULAR-LOCALIZATION OF MOESIN IN DYNAMIC FILOPODIA, RETRACTION FIBERS, AND OTHER STRUCTURES INVOLVED IN SUBSTRATE EXPLORATION, ATTACHMENT, AND CELL-CELL CONTACTS
Amieva, M. R., & FURTHMAYR, H. (1995). SUBCELLULAR-LOCALIZATION OF MOESIN IN DYNAMIC FILOPODIA, RETRACTION FIBERS, AND OTHER STRUCTURES INVOLVED IN SUBSTRATE EXPLORATION, ATTACHMENT, AND CELL-CELL CONTACTS. EXPERIMENTAL CELL RESEARCH, 219(1), 180-196.

MOESIN, EZRIN, AND P205 ARE ACTIN-BINDING PROTEINS ASSOCIATED WITH NEUTROPHIL PLASMA-MEMBRANES
Pestonjamasp, K., Amieva, M. R., Strassel, C. P., Nauseef, W. M., FURTHMAYR, H., & LUNA, E. J. (1995). MOESIN, EZRIN, AND P205 ARE ACTIN-BINDING PROTEINS ASSOCIATED WITH NEUTROPHIL PLASMA-MEMBRANES. MOLECULAR BIOLOGY OF THE CELL, 6(3), 247-259.

RADIXIN IS A COMPONENT OF HEPATOCYTE MICROVILLI IN-SITU
Amieva, M. R., Wilgenbus, K. K., & FURTHMAYR, H. (1994). RADIXIN IS A COMPONENT OF HEPATOCYTE MICROVILLI IN-SITU. EXPERIMENTAL CELL RESEARCH, 210(1), 140-144.

CDNA SEQUENCE AND INTRACELLULAR LOCALIZATION OF HUMAN RADIXIN
Wilgenbus, K. K., Amieva, M., & FURTHMAYR, H. (1994). CDNA SEQUENCE AND INTRACELLULAR LOCALIZATION OF HUMAN RADIXIN. GUSTAV FISCHER VERLAG.

MOESIN, A NEW CYTOSKELETAL PROTEIN AND CONSTITUENT OF FILOPODIA - ITS ROLE IN CELLULAR FUNCTIONS
FURTHMAYR, H., Lankes, W., & Amieva, M. (1992). MOESIN, A NEW CYTOSKELETAL PROTEIN AND CONSTITUENT OF FILOPODIA - ITS ROLE IN CELLULAR FUNCTIONS. KIDNEY INTERNATIONAL, 41(3), 665-670.

EARLY NEUROGENESIS OF THE MOUSE OLFACTORY NERVE - GOLGI AND ELECTRON-MICROSCOPIC STUDIES
MARINPADILLA, M., & Amieva, M. R. (1989). EARLY NEUROGENESIS OF THE MOUSE OLFACTORY NERVE - GOLGI AND ELECTRON-MICROSCOPIC STUDIES. JOURNAL OF COMPARATIVE NEUROLOGY, 288(2), 339-352.