Scott Boyd, MD PhD

Pathologist, Hematopathologist

Assistant Professor of Pathology at the Stanford University Medical Center

Professional Education

Residency: Stanford University School of Medicine (2007) CA

Fellowship: Stanford University School of Medicine (2008) CA

Medical Education: Harvard Medical School (2005) MA

Ph.D., M.I.T., Biology (2004)

B.A., University of Oxford, English Literature (1994)

B.Sc.(Hons), University of Manitoba, Biochemistry (1992)

Board Certification: Clinical Pathology, American Board of Pathology (2009)

Board Certification: Hematopathology, American Board of Pathology (2009)

Honors & Awards

New Scholar Award in Aging, Ellison Medical Foundation (2011)

Walter V. and Idun Berry Fellowship, Stanford University (2008)

Harry B. Neustein Award, Society of Pediatric Pathology (2008)

Young Investigator Award, Society of Pediatric Pathology (2007)

Rhodes Scholarship, University of Oxford (1992-4)

Neurofibromatosis (NF) Foundation, 1st Prize, Neurofibromatosis Foundation (2002)

Pre-doctoral fellowship, Howard Hughes Medical Institutes (1997)

Frank Knox Fellowship, Harvard University (1994)

Thomas Jefferson Award, St. Catherine’s College, Oxford (1994)

Governor General’s Medal, highest undergraduate standing, University of Manitoba (1992)

University Gold Medal, highest standing in honors science, University of Manitoba (1992)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

HIV-1 Envelope gp41 Antibodies Can Originate from Terminal Ileum B Cells that Share Cross-Reactivity with Commensal Bacteria.
Trama, A. M., Moody, M. A., Alam, S. M., Jaeger, F. H., Lockwood, B., & Haynes, B. F. (2014). HIV-1 Envelope gp41 Antibodies Can Originate from Terminal Ileum B Cells that Share Cross-Reactivity with Commensal Bacteria. Cell host & microbe, 16(2), 215-226.

Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements.
Jackson, K. Jl., Liu, Y., Roskin, K. M., Glanville, J., Hoh, R. A., & Boyd, S. D. (2014). Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements. Cell host & microbe, 16(1), 105-114.

Effects of Aging, Cytomegalovirus Infection, and EBV Infection on Human B Cell Repertoires
Wang, C., Liu, Y., Xu, L. T., Jackson, K. Jl., Roskin, K. M., & Boyd, S. D. (2014). Effects of Aging, Cytomegalovirus Infection, and EBV Infection on Human B Cell Repertoires. JOURNAL OF IMMUNOLOGY, 192(2), 603-611.

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.
Bonsignori, M., Wiehe, K., Grimm, S. K., Lynch, R., Yang, G., & Haynes, B. F. (2014). An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1. The Journal of clinical investigation.

Diversity and clonal selection in the human T-cell repertoire.
Qi, Q., Liu, Y., Cheng, Y., Glanville, J., Zhang, D., & Goronzy, J. J. (2014). Diversity and clonal selection in the human T-cell repertoire. Proceedings of the National Academy of Sciences of the United States of America.

Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies.
Kepler, T. B., Liao, H. X., Alam, S. M., Bhaskarabhatla, R., Zhang, R., & Haynes, B. F. (2014). Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies. Cell host & microbe, 16(3), 304-13.

Convergent Antibody Signatures in Human Dengue
Parameswaran, P., Liu, Y., Roskin, K. M., Jackson, K. Kl., Dixit, V. P., & Fire, A. Z. (2013). Convergent Antibody Signatures in Human Dengue. CELL HOST & MICROBE, 13(6), 691-700.

Diagnostic Applications of High-Throughput DNA Sequencing
Boyd, S. D. (2013). Diagnostic Applications of High-Throughput DNA Sequencing. ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 8, 8, 381-410.

Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing
Boyd SD, Marshall EL, Merker JD, Maniar JM, Zhang LN, & Fire AZ. (2009). Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing. Science Translational Medicine, 1(12).

A Balanced Look at the Implications of Genomic (and Other "Omics") Testing for Disease Diagnosis and Clinical Care.
Boyd, S. D., Galli, S. J., Schrijver, I., Zehnder, J. L., Ashley, E. A., & Merker, J. D. (2014). A Balanced Look at the Implications of Genomic (and Other "Omics") Testing for Disease Diagnosis and Clinical Care. Genes, 5(3), 748-66.

Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes.
Merker, J. D., Roskin, K. M., Ng, D., Pan, C., Fisk, D. G., & Gotlib, J. (2013). Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes. Haematologica, 98(11), 1689-1696.

Human lymphocyte repertoires in ageing.
Boyd, S. D., Liu, Y., Wang, C., Martin, V., & Dunn-Walters, D. K. (2013). Human lymphocyte repertoires in ageing. Current opinion in immunology, 25(4), 511-515.

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Liao, H.-X., Lynch, R., Zhou, T., Gao, F., Alam, S. M., & Haynes, B. F. (2013). Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature, 496(7446), 469-476.

Selective Immunophenotyping for Diagnosis of B-cell Neoplasms: Immunohistochemistry and Flow Cytometry Strategies and Results
Boyd, S. D., Natkunam, Y., Allen, J. R., & Warnke, R. A. (2013). Selective Immunophenotyping for Diagnosis of B-cell Neoplasms: Immunohistochemistry and Flow Cytometry Strategies and Results. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 21(2), 116-131.

Integration of Genomic Medicine into Pathology Residency Training The Stanford Open Curriculum
Schrijver, I., Natkunam, Y., Galli, S., & Boyd, S. D. (2013). Integration of Genomic Medicine into Pathology Residency Training The Stanford Open Curriculum. JOURNAL OF MOLECULAR DIAGNOSTICS, 15(2), 141-148.

New tools for classification and monitoring of autoimmune diseases
Maecker, H. T., Lindstrom, T. M., Robinson, W. H., Utz, P. J., Hale, M., & Fathman, C. G. (2012). New tools for classification and monitoring of autoimmune diseases. NATURE REVIEWS RHEUMATOLOGY, 8(6), 317-328.

The Inference of Phased Haplotypes for the Immunoglobulin H Chain V Region Gene Loci by Analysis of VDJ Gene Rearrangements
Kidd, M. J., Chen, Z., Wang, Y., Jackson, K. J., Zhang, L., & Collins, A. M. (2012). The Inference of Phased Haplotypes for the Immunoglobulin H Chain V Region Gene Loci by Analysis of VDJ Gene Rearrangements. JOURNAL OF IMMUNOLOGY, 188(3), 1333-1340.

High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment
Logan, A. C., Gao, H., Wang, C., Sahaf, B., Jones, C. D., & Miklos, D. B. (2011). High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(52), 21194-21199.

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
Liao, H.-X., Chen, X., Munshaw, S., Zhang, R., Marshall, D. J., & Haynes, B. F. (2011). Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. JOURNAL OF EXPERIMENTAL MEDICINE, 208(11), 2237-2249.

Determinants of nucleosome organization in primary human cells
Valouev, A., Johnson, S. M., Boyd, S. D., Smith, C. L., Fire, A. Z., & Sidow, A. (2011). Determinants of nucleosome organization in primary human cells. NATURE, 474(7352), 516-U148.

Benchmarking the performance of human antibody gene alignment utilities using a 454 sequence dataset
Jackson, K. Jl., Boyd, S., Gaeta, B. A., & Collins, A. M. (2010). Benchmarking the performance of human antibody gene alignment utilities using a 454 sequence dataset. BIOINFORMATICS, 26(24), 3129-3130.

Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements
Boyd, S. D., Gaeta, B. A., Jackson, K. J., Fire, A. Z., Marshall, E. L., & Collins, A. M. (2010). Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements. JOURNAL OF IMMUNOLOGY, 184(12), 6986-6992.

A Comparison of Two Methods for Screening CEBPA Mutations in Patients with Acute Myeloid Leukemia
Ahn, J.-Y., Seo, K., Weinberg, O., Boyd, S. D., & Arber, D. A. (2009). A Comparison of Two Methods for Screening CEBPA Mutations in Patients with Acute Myeloid Leukemia. JOURNAL OF MOLECULAR DIAGNOSTICS, 11(4), 319-323.

Features of hemolysis due to Clostridium perfringens infection
Boyd, S. D., Mobley, B. C., Regula, D. P., & Arber, D. A. (2009). Features of hemolysis due to Clostridium perfringens infection. INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 31(3), 364-367.

Everything you wanted to know about small RNA but were afraid to ask
Boyd, S. D. (2008). Everything you wanted to know about small RNA but were afraid to ask. LABORATORY INVESTIGATION, 88(6), 569-578.

Alloimmunization to red blood cell antigens affects clinical outcomes in liver transplant patients
Boyd, S. D., Stenard, F., Lee, D. Kk., Goodnough, L. T., Esquivel, C. O., & Fontaine, M. J. (2007). Alloimmunization to red blood cell antigens affects clinical outcomes in liver transplant patients. LIVER TRANSPLANTATION, 13(12), 1654-1661.

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53
Boyd, S. D., Tsai, K. Y., & Jacks, T. (2000). An intact HDM2 RING-finger domain is required for nuclear exclusion of p53. NATURE CELL BIOLOGY, 2(9), 563-568.

The role of CTLA-4 in regulating Th2 differentiation
OOSTERWEGEL, M. A., Mandelbrot, D. A., Boyd, S. D., Lorsbach, R. B., Jarrett, D. Y., & Sharpe, A. H. (1999). The role of CTLA-4 in regulating Th2 differentiation. JOURNAL OF IMMUNOLOGY, 163(5), 2634-2639.

Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G(1) arrest after gamma-irradiation
Brugarolas, J., Moberg, K., Boyd, S. D., Taya, Y., Jacks, T., & Lees, J. A. (1999). Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G(1) arrest after gamma-irradiation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 96(3), 1002-1007.

CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
Tivol, E. A., Boyd, S. D., Mckeon, S., Borriello, F., Nickerson, P., & Sharpe, A. H. (1997). CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. JOURNAL OF IMMUNOLOGY, 158(11), 5091-5094.

B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
Borriello, F., Sethna, M. P., Boyd, S. D., Schweitzer, A. N., Tivol, E. A., & Sharpe, A. H. (1997). B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation. IMMUNITY, 6(3), 303-313.