Alan G. Cheng

Pediatric otolaryngologist

Professional Education

Residency: University of Washington Medical Center (2006) WA

Internship: University of Washington Medical Center (2000) WA

Fellowship: Children's Hospital Boston (2007) MA

Board Certification: Otolaryngology, American Board of Otolaryngology (2007)

Medical Education: Albert Einstein Medical Center (1999) NY

Fellowship, Children's Hospital Boston, Pediatric Otolaryngology (2007)

Residency, University of Washington, Otolaryngology-HNS (2006)

M.D., Albert Einstein, Medicine (1999)

B.S., Johns Hopkins, Biomedical Engineering (1995)

Honors & Awards

Akiko Yamazaki and Jerry Yang Faculty Scholar, Child Health Research Institute at Stanford (2011)

Herbert Silverstein Otology-Neurotology Award, American Academy of Otolaryngology-Head and Neck Surgery (2010)

Triological Society Career Development Award, Triological Society (2009)

American Otological Society Clinician-Scientist Award, American Otological Society (2008)

Percy Memorial Research Award, American Academy of Otolaryngology-Head and Neck Surgery Foundation (2008)

Shiley Resident Research Award, American Academy of Otolaryngology-Head and Neck Surgery Fundation (2001)

Association for Research in Otolaryngology Resident Travel Award, Association for Research in Otolaryngology (2001, 2002, 2005)

Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo
Cox, B. C., Chai, R., Lenoir, A., Liu, Z., Zhang, L., & Zuo, J. (2014). Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo. DEVELOPMENT, 141(4), 816-829.

Transient, afferent input-dependent, postnatal niche for neural progenitor cells in the cochlear nucleus.
Volkenstein, S., Oshima, K., Sinkkonen, S. T., Corrales, C. E., Most, S. P., & Heller, S. (2013). Transient, afferent input-dependent, postnatal niche for neural progenitor cells in the cochlear nucleus. Proceedings of the National Academy of Sciences of the United States of America, 110(35), 14456-14461.

Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells
Jan, T. A., Chai, R., Sayyid, Z. N., van Amerongen, R., Xia, A., & Cheng, A. G.-L. (2013). Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells. DEVELOPMENT, 140(6), 1196-1206.

Integrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death.
Vu, A. A., Nadaraja, G. S., Huth, M. E., Luk, L., Kim, J., & Cheng, A. G. (2013). Integrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death. PloS one, 8(1).

A simple method for purification of vestibular hair cells and non-sensory cells, and application for proteomic analysis.
Herget, M., Scheibinger, M., Guo, Z., Jan, T. A., Adams, C. M., & Heller, S. (2013). A simple method for purification of vestibular hair cells and non-sensory cells, and application for proteomic analysis. PloS one, 8(6).

Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea
Chai, R., Kuo, B., Wang, T., Liaw, E. J., Xia, A., & Cheng, A. G. (2012). Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(21), 8167-8172.

Dynamic Expression of Lgr5, a Wnt Target Gene, in the Developing and Mature Mouse Cochlea
Chai, R., Xia, A., Wang, T., Jan, T. A., Hayashi, T., & Cheng, A. G.-L. (2011). Dynamic Expression of Lgr5, a Wnt Target Gene, in the Developing and Mature Mouse Cochlea. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY, 12(4), 455-469.

Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity
Alharazneh, A., Luk, L., Huth, M., Monfared, A., Steyger, P. S., & Ricci, A. J. (2011). Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity. PLOS ONE, 6(7).

Intrinsic regenerative potential of murine cochlear supporting cells
Sinkkonen ST, Chai R, Jan, T, Hartman B, & Heller. (2011). Intrinsic regenerative potential of murine cochlear supporting cells. Scientific Reports, 1(26).

Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.
Huth, M. E., Ricci, A. J., & Cheng, A. G. (2011). Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection. International journal of otolaryngology, 2011, 937861-?.

Isolating LacZ-expressing cells from mouse inner ear tissues using flow cytometry.
Jan, T. A., Chai, R., Sayyid, Z. N., & Cheng, A. G. (2011). Isolating LacZ-expressing cells from mouse inner ear tissues using flow cytometry. Journal of visualized experiments : JoVE, (58), e3432-?.

Decompression of the Orbital Apex An Alternate Approach to Surgical Excision for Radiographically Benign Orbital Apex Tumors
Almond, M. C., Cheng, A. G., Schiedler, V., Sires, B. S., Most, S. P., & Jian-Amadi, A. (2009). Decompression of the Orbital Apex An Alternate Approach to Surgical Excision for Radiographically Benign Orbital Apex Tumors. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 135(10), 1015-1018.

Sensorineural hearing loss in patients with cystic fibrosis
Cheng, A. G., Johnston, P. R., Luz, J., Uluer, A., Fligor, B., & Jones, D. T. (2009). Sensorineural hearing loss in patients with cystic fibrosis. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 141(1), 86-90.

Airway management in Nager Syndrome
Ho, A. S., Aleshi, P., Cohen, S. E., Koltai, P. J., & Cheng, A. G. (2009). Airway management in Nager Syndrome. LARYNGOSCOPE, 119, S179-S179.

Airway management in Nager Syndrome
Ho, A. S., Aleshi, P., Cohen, S. E., Koltai, P. J., & Cheng, A. G. (2008). Airway management in Nager Syndrome. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 72(12), 1885-1888.

Melanoacanthoma of the external auditory canal: a case report and review of the literature
Cheng, A. G., Deubner, H., & Whipple, M. E. (2007). Melanoacanthoma of the external auditory canal: a case report and review of the literature. AMERICAN JOURNAL OF OTOLARYNGOLOGY, 28(6), 433-435.

Cerebrospinal fluid leak in the neck: A rare complication of glomus vagale excision
Cheng, A. G., Maronian, N. C., & Futran, N. D. (2006). Cerebrospinal fluid leak in the neck: A rare complication of glomus vagale excision. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 134(2), 334-335.

Mechanisms of hair cell death and protection.
Cheng, A. G., Cunningham, L. L., & Rubel, E. W. (2005). Mechanisms of hair cell death and protection. Current opinion in otolaryngology & head and neck surgery, 13(6), 343-348.

Auramine orange stain with fluorescence microscopy is a rapid and sensitive technique for the detection of cervical lymphadenitis due to mycobacterial infection using fine needle aspiration cytology: a case series
Cheng, A. G., Chang, A., Farwell, D. G., & Agoff, S. N. (2005). Auramine orange stain with fluorescence microscopy is a rapid and sensitive technique for the detection of cervical lymphadenitis due to mycobacterial infection using fine needle aspiration cytology: a case series. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 133(3), 381-385.

Neomycin-induced hair cell death and rapid regeneration in the lateral line of zebrafish (Danio rerio)
Harris, J. A., Cheng, A. G., Cunningham, L. L., MacDonald, G., Raible, D. W., & Rubel, E. W. (2003). Neomycin-induced hair cell death and rapid regeneration in the lateral line of zebrafish (Danio rerio). JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY, 4(2), 219-234.

Hair cell death in the avian basilar papilla: Characterization of the in vitro model and caspase activation
Cheng, A. G., Cunningham, L. L., & Rubel, E. W. (2003). Hair cell death in the avian basilar papilla: Characterization of the in vitro model and caspase activation. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY, 4(1), 91-105.

Caspase activation in hair cells of the mouse utricle exposed to neomycin
Cunningham, L. L., Cheng, A. G., & Rubel, E. W. (2002). Caspase activation in hair cells of the mouse utricle exposed to neomycin. JOURNAL OF NEUROSCIENCE, 22(19), 8532-8540.

Oxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies
Huang, T., Cheng, A. G., Stupak, H., Liu, W., Kim, A., & Van de Water, T. R. (2000). Oxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 18(2-3), 259-270.

Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis
Cheng, A. G., Huang, T., Stracher, A., Kim, A., Liu, W., & Van De Water, T. R. (1999). Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis. BRAIN RESEARCH, 850(1-2), 234-243.

LATERAL VENTRICULAR EFFACEMENT AS AN ISOLATED SONOGRAPHIC FINDING IN PREMATURE-INFANTS - PREVALENCE AND SIGNIFICANCE
Patel, M. D., Cheng, A. G., & Callen, P. W. (1995). LATERAL VENTRICULAR EFFACEMENT AS AN ISOLATED SONOGRAPHIC FINDING IN PREMATURE-INFANTS - PREVALENCE AND SIGNIFICANCE. AMERICAN JOURNAL OF ROENTGENOLOGY, 165(1), 155-159.