Anne Lynn S. Chang, MD

Dermatologist, General dermatologist, Dermatologic oncologist, Cutaneous oncology specialist

Assistant Professor of Dermatology at the Stanford University Medical Center

Skin Cancer Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

General Dermatology Clinic

  • 450 Broadway Street
  • Redwood City, CA 94063
  • Phone: 650-723-6316
Learn More About the Clinic Getting Here Make An Appointment

General Dermatology Clinic in Redwood City

  • 450 Broadway Street
  • Redwood City, CA 94063
  • Phone: 650-723-6316
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Residency: Stanford University Hospital and Clinics - Dermatology Department (2007) CA

Fellowship: Stanford University Hospital and Clinics - Dermatology Department (2004) CA

Residency: UCSF - Department of OB/GYN and REI (2002) CA

Internship: UCSF - Department of OB/GYN and REI (2000) CA

Medical Education: Harvard Medical School (1999) MA

Board Certification: Dermatology, American Board of Dermatology (2007)

MD, Harvard Medical School, Medicine (1999)

Honors & Awards

Research Grant/Award, National Rosacea Society (2014-2015)

Leadership Forum, American Academy of Dermatology (2014)

Research Scholar Award, American Skin Association (2013, 2014)

Career Development Award, Dermatology Foundation (2009)

Fellow, American Academy of Dermatology (2007)

Administrative Appointments

Director of the Advanced Basal Cell Carcinoma Clinic, Stanford Dermatology (2011 - Present)

Director of Adult Dermatological Clinical Trials, Stanford Dermatology (2007 - Present)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Emergence of chemoresistance in a metastatic basal cell carcinoma patient after complete response to hedgehog pathway inhibitor vismodegib (GDC-0449)
Meani, R. E., Lim, S.-W., Chang, A. L. S., & Kelly, J. W. (2014). Emergence of chemoresistance in a metastatic basal cell carcinoma patient after complete response to hedgehog pathway inhibitor vismodegib (GDC-0449). AUSTRALASIAN JOURNAL OF DERMATOLOGY, 55(3), 218-221.

Overall and progression-free survival in metastatic basosquamous cancer: A case series.
Zhu, G. A., Danial, C., Liu, A., Li, S., & Su Chang, A. L. (2014). Overall and progression-free survival in metastatic basosquamous cancer: A case series. Journal of the American Academy of Dermatology, 70(6), 1145-1146.

Precision medicine and precision therapeutics: Hedgehog signaling pathway, basal cell carcinoma and beyond.
Mohan, S. V., & Chang, A. Ls. (2014). Precision medicine and precision therapeutics: Hedgehog signaling pathway, basal cell carcinoma and beyond. Seminars in cutaneous medicine and surgery, 33(2), 68-71.

Only Skin Deep: Optimism and Public Self-Consciousness Did Not Associate With the Placebo Response in a Dermatology Clinical Trial
Garshick, M. K., Chang, A. L. S., & Kimball, A. B. (2014). Only Skin Deep: Optimism and Public Self-Consciousness Did Not Associate With the Placebo Response in a Dermatology Clinical Trial. JOURNAL OF DRUGS IN DERMATOLOGY, 13(6), 719-722.

Identification of genes promoting skin youthfulness
Chang, A. L. S., Atzmon, G., Bergman, A., Atwood, S., Brugmann, S., & Barzilai, N. (2014). Identification of genes promoting skin youthfulness. Journal of Investigative Dermatology, 134(3).

Novel GATA6 Mutations in Patients with Pancreatic Agenesis and Congenital Heart Malformations
Chao, C. S., McKnight, K. D., Cox, K. L., Chang, A. L. S., Kim, S. K., & Feldman, B. J. (2014). Novel GATA6 Mutations in Patients with Pancreatic Agenesis and Congenital Heart Malformations. PLOS ONE, TBD.

Three case reports illustrating reversible cutaneous side effects of vismodegib treatment
Kwong, B., Danial, C., Liu, A., Chun, K., & Chang, A. L. S. (2014). Three case reports illustrating reversible cutaneous side effects of vismodegib treatment. Cutis.

Low rate of dermatology outpatient visits in Asian-Americans: initial survey study for associated patient-related factors
Lingala, B., Wysong, A., Li, S., Truong, A., Kim, D., & Chang, A. L. S. (2014). Low rate of dermatology outpatient visits in Asian-Americans: initial survey study for associated patient-related factors. BioMed Central Dermatology, 14(13).

An investigator-initiated open label clinical trial of vismodegib as a neoadjuvant to surgery for high-risk basal cell carcinoma
Ally, M. S., Wysong, A., Teng, C., Andersen, E., Bailey-Healy, I., & Tang, J. Y. (2014). An investigator-initiated open label clinical trial of vismodegib as a neoadjuvant to surgery for high-risk basal cell carcinoma. Journal of the American Academy of Dermatology, 71(5).

Two Different Scenarios of Squamous Cell Carcinoma Within Advanced Basal Cell Carcinomas: Cases Illustrating the Importance of Serial Biopsy During Vismodegib Usage.
Zhu, G. A., Sundram, U., & Chang, A. L. (2014). Two Different Scenarios of Squamous Cell Carcinoma Within Advanced Basal Cell Carcinomas: Cases Illustrating the Importance of Serial Biopsy During Vismodegib Usage. JAMA dermatology.

Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib
Chang, A. L. S., Solomon, J. A., Hainsworth, J. D., Goldberg, L., McKenna, E., & Weiss, G. J. (2014). Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 70(1), 60-69.

Advanced basal cell carcinoma: epidemiology and therapeutic innovations
Mohan, S., & Chang, A. L. S. (2014). Advanced basal cell carcinoma: epidemiology and therapeutic innovations. Curr Derm Rep, 3(1).

Gorlin syndrome patient with metastatic basal cell carcinoma refractory to Smoothened inhibitors
Zhu, G. A., Li, A. S., & Chang, A. L. S. (2014). Gorlin syndrome patient with metastatic basal cell carcinoma refractory to Smoothened inhibitors. JAMA Dermatology, 150(8).

Oral Smoothened Inhibitor for Advanced Basal Cell Carcinoma of the Hand: A Case Report
Zhu, G. A., Chen, A., & Chang, A. L. S. (2014). Oral Smoothened Inhibitor for Advanced Basal Cell Carcinoma of the Hand: A Case Report. HAND, 9(1).

Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma.
Danial, C., Lingala, B., Balise, R., Oro, A. E., Reddy, S., & Chang, A. Ls. (2013). Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma. British journal of dermatology, 169(3), 673-676.

Geriatric dermatology Part I. Geriatric pharmacology for the dermatologist
Endo, J. O., Wong, J. W., Norman, R. A., & Chang, A. L. S. (2013). Geriatric dermatology Part I. Geriatric pharmacology for the dermatologist. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 68(4).

Rejuvenation of Gene Expression Pattern of Aged Human Skin by Broadband Light Treatment: A Pilot Study
Chang, A. L. S., Bitter, P. H., Qu, K., Lin, M., Rapicavoli, N. A., & Chang, H. Y. (2013). Rejuvenation of Gene Expression Pattern of Aged Human Skin by Broadband Light Treatment: A Pilot Study. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133(2), 394-402.

Phase 1 Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
Weiss, G. J., Miller, W. H., Chang, Al. S., Sharfman, W. H., Ross, R. W., & Rudin, C. M. (2013). Phase 1 Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors. Cancer Clinical Research, doi:10.1158/1078-0432.CCR-12-3654, 19(10).

Surgical excision after neoadjuvant therapy with vismodegib for a locally advanced basal cell carcinoma and additional resistant basal cell carcinomas in a Gorlin's syndrome patient
Chang AS, Atwood S, Tartar D, & Oro AE. (2013). Surgical excision after neoadjuvant therapy with vismodegib for a locally advanced basal cell carcinoma and additional resistant basal cell carcinomas in a Gorlin's syndrome patient. JAMA Dermatology, 149(5).

New onset of keratoacanthomas after vismodegib for locally advanced basal cell carcinomas: a report of two cases
Aasi S, Silkiss R, Tang JY, Epstein E, Wysong A, & Chang AS. (2013). New onset of keratoacanthomas after vismodegib for locally advanced basal cell carcinomas: a report of two cases. JAMA Dermatology, 149(2).

Geriatric Dermatology Review: Major Changes in Skin Function in Older Patients and Their Contribution to Common Clinical Challenges.
Chang, A. L., Wong, J. W., Endo, J. O., & Norman, R. A. (2013). Geriatric Dermatology Review: Major Changes in Skin Function in Older Patients and Their Contribution to Common Clinical Challenges. Journal of the American Medical Directors Association.

Geriatric Dermatology. Part 2. Risk factors and cutaneous signs of elder mistreatment for the dermatologist
Chang AS, Wong J, Endo JO, & Norman R. (2013). Geriatric Dermatology. Part 2. Risk factors and cutaneous signs of elder mistreatment for the dermatologist. Journal of the American Academy of Dermatology, 68(4).

Vismodegib for periocular and orbital basal cell carcinoma
Gill, H., Moscato, E. E., Chang, Al. S., Soon, S., & Silkiss, R. (2013). Vismodegib for periocular and orbital basal cell carcinoma. JAMA Ophthalmology, 131(12).

A simple intervention to reinforce awareness of tanning bed use and skin cancer in non-medical skin care professionals in Southern California
Ng, A. T., Chang, A. L. S., Cockburn, M., & Peng, D. H. (2012). A simple intervention to reinforce awareness of tanning bed use and skin cancer in non-medical skin care professionals in Southern California. INTERNATIONAL JOURNAL OF DERMATOLOGY, 51(11), 1307-1312.

Hedgehog pathway inhibition and the race against tumor evolution
Atwood, S. X., Chang, A. L. S., & Oro, A. E. (2012). Hedgehog pathway inhibition and the race against tumor evolution. JOURNAL OF CELL BIOLOGY, 199(2), 193-197.

Translocation Affecting Sonic Hedgehog Genes in Basal-Cell Carcinoma
Gomez-Ospina, N., Chang, A. L. S., Qu, K., & Oro, A. E. (2012). Translocation Affecting Sonic Hedgehog Genes in Basal-Cell Carcinoma. NEW ENGLAND JOURNAL OF MEDICINE, 366(23), 2233-2234.

Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
Sekulic, A., Migden, M. R., Oro, A. E., Dirix, L., Lewis, K. D., & Hauschild, A. (2012). Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma. NEW ENGLAND JOURNAL OF MEDICINE, 366(23), 2171-2179.

A Randomized, Double-Blind, Placebo-Controlled, Pilot Study to Assess the Efficacy and Safety of Clindamycin 1.2% and Tretinoin 0.025% Combination Gel for the Treatment of Acne Rosacea Over 12 Weeks
Chang, A. L. S., Alora-Palli, M., Lima, X. T., Chang, T. C., Cheng, C., & Kimball, A. B. (2012). A Randomized, Double-Blind, Placebo-Controlled, Pilot Study to Assess the Efficacy and Safety of Clindamycin 1.2% and Tretinoin 0.025% Combination Gel for the Treatment of Acne Rosacea Over 12 Weeks. JOURNAL OF DRUGS IN DERMATOLOGY, 11(3), 333-339.

An Exploratory Study to Determine the Association Between Assessed Facial Skin Aging and Plasma Isoprostane Levels in Middle-Aged Japanese Women
Chang, A. L. S., Lingala, B., Chang, T. C., Kern, D. G., Wood, S. M., & Knaggs, H. E. (2012). An Exploratory Study to Determine the Association Between Assessed Facial Skin Aging and Plasma Isoprostane Levels in Middle-Aged Japanese Women. DERMATOLOGIC SURGERY, 38(3), 462-470.

Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers
Spitale RC, Cheng MY, Chun KA, Gorell ES, Munoz CA, & Chang AS. (2012). Differential effects of dietary supplements on metabolomic profile of smokers versus non-smokers. Genome Medicine, 4(2).

Native American Skin Offerings Mistaken for Acne Scars in a College Undergraduate
Wong J, Truong AK, & Chang AS. (2012). Native American Skin Offerings Mistaken for Acne Scars in a College Undergraduate. Archives of Dermatology, 148(10).

A Little Known But Life Threatening Association of Bullous Pemphigoid and Acquired Hemophilia: Case Report and Review of the Literature
Nguyen C, Gordon J, & Chang AS. (2012). A Little Known But Life Threatening Association of Bullous Pemphigoid and Acquired Hemophilia: Case Report and Review of the Literature. Journal of Clinical and Experimental Dermatology Research dx.doi.org/10.4172/2155-9554.S6-003.

Stratification of highest risk patients with chronic skin ulcers in a Stanford retrospective cohort includes diabetes, need for systemic antibiotics and albumin levels
Amir O, Liu A, & Chang AS. (2012). Stratification of highest risk patients with chronic skin ulcers in a Stanford retrospective cohort includes diabetes, need for systemic antibiotics and albumin levels. Ulcers, ID7678561.

A randomized double-blind, placebo-controlled pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks
Chang, As., Alora-Palli M, Lima XT, Chang TC, Cheng C, & Kimball AB. (2012). A randomized double-blind, placebo-controlled pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks. Journal of Drugs in Dermatology, 11(3).

More Than Just A Coincidence: Herpes Zoster and Acne Rosacea Appearing Together as Wolf?s Isotopic Response in an Asian Female
Fijalkowski N, W. A. K. P. C. As. (2012). More Than Just A Coincidence: Herpes Zoster and Acne Rosacea Appearing Together as Wolf?s Isotopic Response in an Asian Female. International Journal of Case Reports and Images, Feb.

Initial assessment of tumor regrowth after vismodegib in advanced basal cell carcinoma patients
Chang AS, & Oro AE. (2012). Initial assessment of tumor regrowth after vismodegib in advanced basal cell carcinoma patients. Archives of Dermatology, Aug 20(epub).

A case of Cinderella: erythema dyschromia perstans (ashy dermatosis or dermatosis cinecienta)
Munoz CA, & Chang AS. (2011). A case of Cinderella: erythema dyschromia perstans (ashy dermatosis or dermatosis cinecienta). SkinMed: Dermatology for the Clinician, 9(1).

Association of facial skin aging and vitamin D levels in middle-aged white women
Chang, A. L. S., Fu, T., Amir, O., & Tang, J. Y. (2010). Association of facial skin aging and vitamin D levels in middle-aged white women. CANCER CAUSES & CONTROL, 21(12), 2315-2316.

Initial Clinical Experience Using a Novel Ultraportable Negative Pressure Wound Therapy Device
Fong, K. D., Hu, D., Eichstadt, S. L., Gorell, E., Munoz, C. A., & Chang, A. L. S. (2010). Initial Clinical Experience Using a Novel Ultraportable Negative Pressure Wound Therapy Device. WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE, 22(9), 230-236.

A Two-Year, Double-Blind, Randomized Placebo-Controlled Trial of Oral Green Tea Polyphenols on the Long-Term Clinical and Histologic Appearance of Photoaging Skin
Janjua, R., Munoz, C., Gorell, E., Rehmus, W., Egbert, B., & Chang, A. L. S. (2009). A Two-Year, Double-Blind, Randomized Placebo-Controlled Trial of Oral Green Tea Polyphenols on the Long-Term Clinical and Histologic Appearance of Photoaging Skin. DERMATOLOGIC SURGERY, 35(7), 1057-1065.

Preventing diabetic skin ulcers in Latinos-- no small feat: development of a Spanish and English survey for fast assessment of lower extremity skin care practices
Munoz, Ca., Chang, & AS. (2009). Preventing diabetic skin ulcers in Latinos-- no small feat: development of a Spanish and English survey for fast assessment of lower extremity skin care practices. Archives of Dermatology, 145(4).

Oral contraceptives for acne and sexual practices
Abuabara K, & Chang AL. (2009). Oral contraceptives for acne and sexual practices. Journal of the American Academy of Dermatology, 60(3).

Adoption of Western Culture By Californian Asian Americans: Attitudes and Practices Promoting Sun Exposure
Gorell ES, Lee C, Munoz CA, & Chang AS. (2009). Adoption of Western Culture By Californian Asian Americans: Attitudes and Practices Promoting Sun Exposure. Archives of Dermatology, 145(5).

Alefacept for erosive lichen planus: A case series
Chang, A. L. S., Badger, J., Rehmus, W., & Kimball, A. B. (2008). Alefacept for erosive lichen planus: A case series. JOURNAL OF DRUGS IN DERMATOLOGY, 7(4), 379-383.

A case of argyria after colloidal silver ingestion
Chang, A. L. S., Khosravi, V., & Egbert, B. (2006). A case of argyria after colloidal silver ingestion. JOURNAL OF CUTANEOUS PATHOLOGY, 33(12), 809-811.

Risk factors associated with striae gravidarum
Chang, A. Ls., Agredano, Y. Z., & Kimball, A. B. (2004). Risk factors associated with striae gravidarum. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 51(6), 881-885.

Salpingectomy or proximal tubal occlusion of unilateral hydrosalpinx increases the potential for spontaneous pregnancy.
Sagoskin AW, Lessey BA, Mottla GL, Richter KS, Chetkowski RJ, & Stillman RJ. (2003). Salpingectomy or proximal tubal occlusion of unilateral hydrosalpinx increases the potential for spontaneous pregnancy. Human Reprod, 18(12).

Obstetric attending physician characteristics and their impact on vacuum and forceps delivery rates: University of California at San Francisco experience from 1977 to 1999.
Chang AL, Noah MS, & Laros RK. (2002). Obstetric attending physician characteristics and their impact on vacuum and forceps delivery rates: University of California at San Francisco experience from 1977 to 1999. Am J Obstet Gynecol, 186(6).

Talin and vinculin play distinct roles in filopodial motility in the neuronal growth cone
Sydor AM, Su AL, Wang FS, Xu A, & Jay DG. (1996). Talin and vinculin play distinct roles in filopodial motility in the neuronal growth cone. J Cell Biol., 134(5).

Chromophore-assisted laser inactivation of patched protein switches cell fate in the larval visual system of Drosophila.
Chromophore-assisted laser inactivation of patched protein switches cell fate in the larval visual system of Drosophila. (1996). Chromophore-assisted laser inactivation of patched protein switches cell fate in the larval visual system of Drosophila. Proc Natl Acad Sci U S A, 91(7).