Chris Cartwright, MD

Gastroenterologist, Inflammatory bowel disease specialist

Professor of Medicine (Gastroenterology and Hepatology)

Digestive Health Center

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-736-5555
Learn More About the Clinic Getting Here Make An Appointment

Digestive Health Center at Blake Wilbur Building

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-736-5555
Learn More About the Clinic Getting Here Make An Appointment

Digestive Health - Endoscopy Suite at Stanford

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-736-5555
Learn More About the Clinic Getting Here Make An Appointment

Digestive Health - Endoscopy Suite in Redwood City

  • 450 Broadway Street
  • Redwood City, CA 94063
  • Phone: 650-736-5555
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

BS, Stanford University, Biology (1973)

MD, University of Utah, Medicine (1978)

Internship: UCSD Medical Center (1979) CA

Residency: UCSD Medical Center (1981) CA

Fellowship: UCSD Medical Center (1984) CA

Research Associate, The Salk Institute, Cancer Biology (1989)

Board Certification: Internal Medicine, American Board of Internal Medicine (1981)

Board Certification: Gastroenterology, American Board of Internal Medicine (1987)

Medical Education: University of Utah School of Medicine (1978) UT

Honors & Awards

Outstanding AGA Women in Science, American Gastroenterological Association (2008)

Premier Physician Award, Crohn's & Colitis Foundation of America - Greater Bay Area Chapter (2000)

Member, American Society for Clinical Investigation (1995)

Administrative Appointments

Director, Program for Inflammatory Bowel Diseases, Stanford University School of Medicine (1989 - Present)

Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis
Swaminathan, G., & Cartwright, C. A. (2012). Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis. ONCOGENE, 31(3), 376-389.

A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways
Mamidipudi, V., & Cartwright, C. A. (2009). A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. ONCOGENE, 28(50), 4421-4433.

Crohn's Colitis Complicated by Cytomegalovirus Infection
Levesque, B. G., Pai, R., & Cartwright, C. A. (2009). Crohn's Colitis Complicated by Cytomegalovirus Infection. DIGESTIVE DISEASES AND SCIENCES, 54(9), 1864-1867.

RACK1 inhibits colonic cell growth by regulating Src activity at cell cycle checkpoints
Mamidipudi, V., Dhillon, N. K., Parman, T., Miller, L. D., Lee, K. C., & Cartwright, C. A. (2007). RACK1 inhibits colonic cell growth by regulating Src activity at cell cycle checkpoints. ONCOGENE, 26(20), 2914-2924.

Peptide modulators of Src activity in G(1) regulate entry into S phase and proliferation of NIH 3T3 cells
Mamidipudi, V., Miller, L. D., Mochly-Rosen, D., & Cartwright, C. A. (2007). Peptide modulators of Src activity in G(1) regulate entry into S phase and proliferation of NIH 3T3 cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 352(2), 423-430.

RACK1 regulates G(1)/S progression by suppressing Src kinase activity
Mamidipudi, V., Zhang, J., Lee, K. C., & Cartwright, C. A. (2004). RACK1 regulates G(1)/S progression by suppressing Src kinase activity. MOLECULAR AND CELLULAR BIOLOGY, 24(15), 6788-6798.

RACK1 regulates Src-mediated Sam68 and p190RhoGAP signaling
Miller, L. D., Lee, K. C., Mochly-Rosen, D., & Cartwright, C. A. (2004). RACK1 regulates Src-mediated Sam68 and p190RhoGAP signaling. ONCOGENE, 23(33), 5682-5686.

RACK1 inhibits the serum- and anchorage-independent growth of v-Src transformed cells
Mamidipudi, V., Chang, B. Y., Harte, R. A., Lee, K. C., & Cartwright, C. A. (2004). RACK1 inhibits the serum- and anchorage-independent growth of v-Src transformed cells. FEBS LETTERS, 567(2-3), 321-326.

Cytomegalovirus infection in steroid-refractory ulcerative colitis - A case-control study
Kambham, N., Vij, R., Cartwright, C. A., & Longacre, T. (2004). Cytomegalovirus infection in steroid-refractory ulcerative colitis - A case-control study. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 28(3), 365-373.

Detection of protein kinase-binding partners by the yeast two-hybrid analysis.
Chang, B. Y., & Cartwright, C. A. (2003). Detection of protein kinase-binding partners by the yeast two-hybrid analysis. Methods in molecular biology (Clifton, N.J.), 233, 327-343.

RACK1: a novel substrate for the Src protein-tyrosine kinase
Chang, B. Y., Harte, R. A., & Cartwright, C. A. (2002). RACK1: a novel substrate for the Src protein-tyrosine kinase. ONCOGENE, 21(50), 7619-7629.

The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1
Chang, B. Y., Chiang, M. L., & Cartwright, C. A. (2001). The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(23), 20346-20356.

The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism
Walter, A. O., Peng, Z. Y., & Cartwright, C. A. (1999). The Shp-2 tyrosine phosphatase activates the Src tyrosine kinase by a non-enzymatic mechanism. ONCOGENE, 18(11), 1911-1920.

RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of Src tyrosine kinases and growth of NIH 3T3 cells
Chang, B. Y., Conroy, K. B., Machleder, E. M., & Cartwright, C. A. (1998). RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of Src tyrosine kinases and growth of NIH 3T3 cells. MOLECULAR AND CELLULAR BIOLOGY, 18(6), 3245-3256.

REGULATION OF THE SRC TYROSINE KINASE AND SYP TYROSINE PHOSPHATASE BY THEIR CELLULAR-ASSOCIATION
Peng, Z. Y., & Cartwright, C. A. (1995). REGULATION OF THE SRC TYROSINE KINASE AND SYP TYROSINE PHOSPHATASE BY THEIR CELLULAR-ASSOCIATION. ONCOGENE, 11(10), 1955-1962.

SRC ACTIVITY INCREASES AND YES ACTIVITY DECREASES DURING MITOSIS OF HUMAN COLON-CARCINOMA CELLS
Park, J., & Cartwright, C. A. (1995). SRC ACTIVITY INCREASES AND YES ACTIVITY DECREASES DURING MITOSIS OF HUMAN COLON-CARCINOMA CELLS. MOLECULAR AND CELLULAR BIOLOGY, 15(5), 2374-2382.

ELEVATED C-YES TYROSINE KINASE-ACTIVITY IN PREMALIGNANT LESIONS OF THE COLON
PENA, S. V., Melhem, M. F., Meisler, A. I., & Cartwright, C. A. (1995). ELEVATED C-YES TYROSINE KINASE-ACTIVITY IN PREMALIGNANT LESIONS OF THE COLON. GASTROENTEROLOGY, 108(1), 117-124.

ELEVATED C-SRC TYROSINE KINASE-ACTIVITY IN PREMALIGNANT EPITHELIA OF ULCERATIVE-COLITIS
Cartwright, C. A., COAD, C. A., & Egbert, B. M. (1994). ELEVATED C-SRC TYROSINE KINASE-ACTIVITY IN PREMALIGNANT EPITHELIA OF ULCERATIVE-COLITIS. JOURNAL OF CLINICAL INVESTIGATION, 93(2), 509-515.

C-YES TYROSINE KINASE-ACTIVITY IN HUMAN COLON-CARCINOMA
Park, J. S., Meisler, A. I., & Cartwright, C. A. (1993). C-YES TYROSINE KINASE-ACTIVITY IN HUMAN COLON-CARCINOMA. ONCOGENE, 8(10), 2627-2635.

INTESTINAL CRYPT CELLS CONTAIN HIGHER LEVELS OF CYTOSKELETAL-ASSOCIATED PP60C-SRC PROTEIN TYROSINE KINASE-ACTIVITY THAN DO DIFFERENTIATED ENTEROCYTES
Cartwright, C. A., MAMAJIWALLA, S., SKOLNICK, S. A., Eckhart, W., & Burgess, D. R. (1993). INTESTINAL CRYPT CELLS CONTAIN HIGHER LEVELS OF CYTOSKELETAL-ASSOCIATED PP60C-SRC PROTEIN TYROSINE KINASE-ACTIVITY THAN DO DIFFERENTIATED ENTEROCYTES. ONCOGENE, 8(4), 1033-1039.

THE HEPATITIS-B VIRUS-ENCODED TRANSCRIPTIONAL TRANSACTIVATOR HBX APPEARS TO BE A NOVEL PROTEIN SERINE THREONINE KINASE
Wu, J. Y., Zhou, Z. Y., Judd, A., Cartwright, C. A., & Robinson, W. S. (1990). THE HEPATITIS-B VIRUS-ENCODED TRANSCRIPTIONAL TRANSACTIVATOR HBX APPEARS TO BE A NOVEL PROTEIN SERINE THREONINE KINASE. CELL, 63(4), 687-695.

Relapse of Intestinal and Hepatic Amebiasis After Treatment
Hwang, E. W., Cheung, L., Mojtahed, A., & Cartwright, C. A. (2011). Relapse of Intestinal and Hepatic Amebiasis After Treatment. DIGESTIVE DISEASES AND SCIENCES, 56(3), 677-680.

Characterization of In Vivo Keratin 19 Phosphorylation on Tyrosine-391
Zhou, Q., Snider, N. T., Liao, J., Li, D. H., Hong, A., & Omary, M. B. (2010). Characterization of In Vivo Keratin 19 Phosphorylation on Tyrosine-391. PLOS ONE, 5(10).

Distal Extrahepatic Cholangiocarcinoma Presenting as Cholangitis
Lee, M., Banerjee, S., Posner, M. C., & Cartwright, C. A. (2010). Distal Extrahepatic Cholangiocarcinoma Presenting as Cholangitis. DIGESTIVE DISEASES AND SCIENCES, 55(7), 1852-1855.