Constance Chu, MD
Sports medicine surgeon
As Director of the multi-disciplinary Joint Preservation Center structured to seamlessly integrate basic, translational and clinical research with clinical practice, Dr. Chu developed the center to advance the concept of early diagnosis and treatment of cartilage injury and degeneration as a strategy to delay or prevent the onset of disabling osteoarthritis. Towards this end, she is leading innovative translational research from bench to bedside in three main areas: quantitative imaging and biomarker development for early diagnosis and staging of joint and cartilage injury and degeneration; cartilage tissue engineering and stem cell based cartilage repair; and molecular and biological therapies for joint restoration and joint rejuvenation. Her research efforts have led to more than 30 professional awards and honors to include a Kappa Delta Award, considered to be the highest research honor in Orthopedic Surgery.
Dr. Chu also regularly holds leadership and committee positions in major professional organizations such as the American Association of Orthopedic Surgeons (AAOS) and the American Orthopedic Association (AOA). In her subspecialty of Orthopedic Sports Medicine, she is a past President of the Forum Sports Focus Group, a member of the Herodicus Society of leaders in Sports Medicine, and immediate past Chair of the American Orthopedic Society for Sports Medicine (AOSSM) Research Council. She is alumnus of the highly AOA American, British, Canadian (ABC) Traveling Fellowship and the AOSSM Traveling Fellowship, opportunities enacted to recognize and promote the careers of emerging leaders in orthopedic surgery and orthopedic sports medicine, respectively.
Fellowship: Brigham and Women's Hospital Harvard Medical School (1999) MA
Residency: UCSD Medical Center (1998) CA
Internship: UCSD Medical Center (1993) CA
Undergraduate, US Military Academy at West Point, Engineering Core Foreign Languages
Medical Education: Harvard Medical School (1992) MA
Board Certification: Orthopaedic Surgery, American Board of Orthopaedic Surgery (2001)
The Effect of Platelet-Rich Plasma Formulations and Blood Products on Human Synoviocytes Implications for Intra-articular Injury and Therapy
Braun, H. J., Kim, H. J., Chu, C. R., & Dragoo, J. L. (2014). The Effect of Platelet-Rich Plasma Formulations and Blood Products on Human Synoviocytes Implications for Intra-articular Injury and Therapy. AMERICAN JOURNAL OF SPORTS MEDICINE, 42(5), 1204-1210.
Articular cartilage changes in maturing athletes: new targets for joint rejuvenation.
Luria, A., & Chu, C. R. (2014). Articular cartilage changes in maturing athletes: new targets for joint rejuvenation. Sports health, 6(1), 18-30.
Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis.
Lepus, C. M., Song, J. J., Wang, Q., Wagner, C. A., Lindstrom, T. M., & Robinson, W. H. (2014). Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis. Arthritis & rheumatology (Hoboken, N.J.), 66(1), 101-106.
Persistence, Localization, and External Control of Transgene Expression After Single Injection of Adeno-Associated Virus into Injured Joints
Lee, H. H., O'Malley, M. J., Friel, N. A., Payne, K. A., Qiao, C., & Chu, C. R. (2013). Persistence, Localization, and External Control of Transgene Expression After Single Injection of Adeno-Associated Virus into Injured Joints. HUMAN GENE THERAPY, 24(4), 457-466.