David Drover

Anesthesiologist

Professional Education

Residency: Dalhousie University (1995) Canada

Internship: Dalhousie University (1991) Canada

Board Certification: Anesthesia, Royal College of Physicians and Surgeons (1995)

Medical Education: Dalhousie University (1990) Canada

BSc, Dalhousie University, Science (1985)

MSc, Dalhousie University, Clinical Chemistry (1988)

MD, Dalhousie University, Medicine (1990)

FRCP(C), Dalhousie University, Anesthesia (1995)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

The effects of ketamine on dexmedetomidine-induced electrophysiologic changes in children.
Char, D., Drover, D. R., Motonaga, K. S., Gupta, S., Miyake, C. Y., & Hammer, G. B. (2013). The effects of ketamine on dexmedetomidine-induced electrophysiologic changes in children. Paediatric anaesthesia, 23(10), 898-905.

Comparison of a New Cobinamide-Based Method to a Standard Laboratory Method for Measuring Cyanide in Human Blood
Swezey, R., Shinn, W., Green, C., Drover, D. R., Hammer, G. B., & Boss, G. R. (2013). Comparison of a New Cobinamide-Based Method to a Standard Laboratory Method for Measuring Cyanide in Human Blood. JOURNAL OF ANALYTICAL TOXICOLOGY, 37(6), 382-385.

Sodium nitroprusside is not associated with metabolic acidosis during intraoperative infusion in children
Hammer, G. B., Connolly, S. G., Schulman, S. R., Lewandowski, A., Cohane, C., & Drover, D. R. (2013). Sodium nitroprusside is not associated with metabolic acidosis during intraoperative infusion in children. BMC ANESTHESIOLOGY, 13.

Aversive and Reinforcing Opioid Effects A Pharmacogenomic Twin Study
Angst, M. S., Lazzeroni, L. C., Phillips, N. G., Drover, D. R., Tingle, M., & Clark, J. D. (2012). Aversive and Reinforcing Opioid Effects A Pharmacogenomic Twin Study. ANESTHESIOLOGY, 117(1), 22-37.

Pain sensitivity and opioid analgesia: A pharmacogenomic twin study
Angst, M. S., Phillips, N. G., Drover, D. R., Tingle, M., Ray, A., & Clark, J. D. (2012). Pain sensitivity and opioid analgesia: A pharmacogenomic twin study. PAIN, 153(7), 1397-1409.

The Pharmacokinetics of Ketorolac After Single Postoperative Intranasal Administration in Adolescent Patients
Drover, D. R., Hammer, G. B., & Anderson, B. J. (2012). The Pharmacokinetics of Ketorolac After Single Postoperative Intranasal Administration in Adolescent Patients. ANESTHESIA AND ANALGESIA, 114(6), 1270-1276.

Intrathecal fentanyl added to bupivacaine and morphine for cesarean delivery may induce a subtle acute opioid tolerance
Carvalho, B., Drover, D. R., Ginosar, Y., Cohen, S. E., & Riley, E. T. (2012). Intrathecal fentanyl added to bupivacaine and morphine for cesarean delivery may induce a subtle acute opioid tolerance. INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA, 21(1), 29-34.

Comparative clinical effects of hydromorphone and morphine: a meta-analysis
Felden, L., Walter, C., Harder, S., Treede, R.-D., Kayser, H., & Loetsch, J. (2011). Comparative clinical effects of hydromorphone and morphine: a meta-analysis. BRITISH JOURNAL OF ANAESTHESIA, 107(3), 319-328.

Prior epidural lidocaine alters the pharmacokinetics and drug effects of extended-release epidural morphine (DepoDur®) after cesarean delivery.
Atkinson Ralls, L., Drover, D. R., Clavijo, C. F., & Carvalho, B. (2011). Prior epidural lidocaine alters the pharmacokinetics and drug effects of extended-release epidural morphine (DepoDur®) after cesarean delivery. Anesthesia and analgesia, 113(2), 251-258.

TITRATION OF SEVOFLURANE IN ELDERLY PATIENTS: BLINDED, RANDOMIZED CLINICAL TRIAL, IN NON-CARDIAC SURGERY AFTER BETA-ADRENERGIC BLOCKADE
Drover, D. R., Schmiesing, C., Buchin, A. F., Ortega, H. R., Tanner, J. W., & Macario, A. (2011). TITRATION OF SEVOFLURANE IN ELDERLY PATIENTS: BLINDED, RANDOMIZED CLINICAL TRIAL, IN NON-CARDIAC SURGERY AFTER BETA-ADRENERGIC BLOCKADE. JOURNAL OF CLINICAL MONITORING AND COMPUTING, 25(3), 175-181.

A sensitive assay for the quantification of morphine and its active metabolites in human plasma and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry
Clavijo, C. F., Hoffman, K. L., Thomas, J. J., Carvalho, B., Chu, L. F., & Galinkin, J. L. (2011). A sensitive assay for the quantification of morphine and its active metabolites in human plasma and dried blood spots using high-performance liquid chromatography-tandem mass spectrometry. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 400(3), 715-728.

The effectiveness of preemptive sphenopalatine ganglion block on postoperative pain and functional outcomes after functional endoscopic sinus surgery
Cho, D.-Y., Drover, D. R., Nekhendzy, V., Butwick, A. J., Collins, J., & Hwang, P. H. (2011). The effectiveness of preemptive sphenopalatine ganglion block on postoperative pain and functional outcomes after functional endoscopic sinus surgery. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 1(3), 212-218.

ED50 and ED95 of Intrathecal Bupivacaine in Morbidly Obese Patients Undergoing Cesarean Delivery
Carvalho, B., Collins, J., Drover, D. R., Ralls, L. A., & Riley, E. T. (2011). ED50 and ED95 of Intrathecal Bupivacaine in Morbidly Obese Patients Undergoing Cesarean Delivery. ANESTHESIOLOGY, 114(3), 529-535.

Morphine and its metabolites after patient-controlled analgesia: considerations for respiratory depression
Sam, W. J., Mackey, S. C., Loetsch, J., & Drover, D. R. (2011). Morphine and its metabolites after patient-controlled analgesia: considerations for respiratory depression. JOURNAL OF CLINICAL ANESTHESIA, 23(2), 102-106.

Efficacy, Safety, and Pharmacokinetics of Sugammadex for the Reversal of Rocuronium-induced Neuromuscular Blockade in Elderly Patients
McDonagh, D. L., Benedict, P. E., Kovac, A. L., Drover, D. R., Brister, N. W., & Monk, T. G. (2011). Efficacy, Safety, and Pharmacokinetics of Sugammadex for the Reversal of Rocuronium-induced Neuromuscular Blockade in Elderly Patients. ANESTHESIOLOGY, 114(2), 318-329.

Opioid Pharmacogenomics Using a Twin Study Paradigm: Methods and Procedures for Determining Familial Aggregation and Heritability
Angst, M. S., Phillips, N. G., Drover, D. R., Tingle, M., Galinkin, J. L., & Clark, J. D. (2010). Opioid Pharmacogenomics Using a Twin Study Paradigm: Methods and Procedures for Determining Familial Aggregation and Heritability. TWIN RESEARCH AND HUMAN GENETICS, 13(5), 412-425.

Pharmacokinetic-pharmacodynamic modeling of the hypotensive effect of remifentanil in infants undergoing cranioplasty
Standing, J. F., Hammer, G. B., Sam, W. J., & Drover, D. R. (2010). Pharmacokinetic-pharmacodynamic modeling of the hypotensive effect of remifentanil in infants undergoing cranioplasty. PEDIATRIC ANESTHESIA, 20(1), 7-18.

A POOR CORRELATION EXISTS BETWEEN OSCILLOMETRIC AND RADIAL ARTERIAL BLOOD PRESSURE AS MEASURED BY THE PHILIPS MP90 MONITOR
Mireles, S. A., Jaffe, R. A., Drover, D. R., & Brock-Utne, J. G. (2009). A POOR CORRELATION EXISTS BETWEEN OSCILLOMETRIC AND RADIAL ARTERIAL BLOOD PRESSURE AS MEASURED BY THE PHILIPS MP90 MONITOR. JOURNAL OF CLINICAL MONITORING AND COMPUTING, 23(3), 169-174.

No evidence for the development of acute tolerance to analgesic, respiratory depressant and sedative opioid effects in humans
Angst, M. S., Chu, L. F., Tingle, M. S., Shafer, S. L., Clark, J. D., & Drover, D. R. (2009). No evidence for the development of acute tolerance to analgesic, respiratory depressant and sedative opioid effects in humans. PAIN, 142(1-2), 17-26.

Determination of the pharmacodynamic interaction of propofol and dexmedetomidine during esophagogastroduodenoscopy in children
Hammer, G. B., Sam, W. J., Chen, M. I., Golianu, B., & Drover, D. R. (2009). Determination of the pharmacodynamic interaction of propofol and dexmedetomidine during esophagogastroduodenoscopy in children. PEDIATRIC ANESTHESIA, 19(2), 138-144.

Population pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery.
Sam, W. J., Hammer, G. B., & Drover, D. R. (2009). Population pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery. BMC anesthesiology, 9, 5-?.

The effects of dexmedetomidine on cardiac electrophysiology in children
Hammer, G. B., Drover, D. R., Cao, H., Jackson, E., Williams, G. D., & Dubin, A. M. (2008). The effects of dexmedetomidine on cardiac electrophysiology in children. ANESTHESIA AND ANALGESIA, 106(1), 79-83.

Pharmacokinetics And Pharmacodynamics Of Fenoldopam Mesylate For Blood Pressure Control In Pediatric Patients.
Hammer, G. B., Verghese, S. T., Drover, D. R., Yaster, M., & Tobin, J. R. (2008). Pharmacokinetics And Pharmacodynamics Of Fenoldopam Mesylate For Blood Pressure Control In Pediatric Patients. BMC anesthesiology, 8, 6-?.

Randomized, dose-finding, Phase II study of the selective relaxant binding drug, sugammadex, capable of safely reversing profound rocuronium-induced neuromuscular block
Groudine, S. B., Soto, R., Lien, C., Drover, D., & Roberts, K. (2007). Randomized, dose-finding, Phase II study of the selective relaxant binding drug, sugammadex, capable of safely reversing profound rocuronium-induced neuromuscular block. ANESTHESIA AND ANALGESIA, 104(3), 555-562.

Patient state index.
Drover, D., & ORTEGA, H. R. (2006). Patient state index. Best practice & research. Clinical anaesthesiology, 20(1), 121-128.

Pharmacology of drugs formulated with DepoFoaM (TM) - A sustained release drug delivery system for parenteral administration using multivesicular liposome technology
Angst, M. S., & Drover, D. R. (2006). Pharmacology of drugs formulated with DepoFoaM (TM) - A sustained release drug delivery system for parenteral administration using multivesicular liposome technology. CLINICAL PHARMACOKINETICS, 45(12), 1153-1176.

The ED50 and ED95 of intrathecal isobaric bupivacaine with opioids for cesarean delivery
Carvalho, B., Durbin, M., Drover, D. R., Cohen, S. E., Ginosar, Y., & Riley, E. T. (2005). The ED50 and ED95 of intrathecal isobaric bupivacaine with opioids for cesarean delivery. ANESTHESIOLOGY, 103(3), 606-612.

The use of a sum of inverse Gaussian functions to describe the absorption profile of drugs exhibiting complex absorption
Csajka, C., Drover, D., & Verotta, D. (2005). The use of a sum of inverse Gaussian functions to describe the absorption profile of drugs exhibiting complex absorption. PHARMACEUTICAL RESEARCH, 22(8), 1227-1235.

Postoperative analgesia after spinal blockade in infants and children undergoing cardiac surgery
Hammer, G. B., Ramamoorthy, C., Cao, H., Williams, G. D., Boltz, M. G., & Drover, D. R. (2005). Postoperative analgesia after spinal blockade in infants and children undergoing cardiac surgery. ANESTHESIA AND ANALGESIA, 100(5), 1283-1288.

Determination of the pharmacodynamic interaction of propofol and remifentanil during esophagogastroduodenoscopy in children
Drover, D. R., Litalien, C., Wellis, V., Shafer, S. L., & Hammer, G. B. (2004). Determination of the pharmacodynamic interaction of propofol and remifentanil during esophagogastroduodenoscopy in children. ANESTHESIOLOGY, 100(6), 1382-1386.

ED50 and ED95 of intrathecal hyperbaric bupivacaine coadministered with opioids for cesarean delivery
Ginosar, Y., Mirikatani, E., Drover, D. R., Cohen, S. E., & Riley, E. T. (2004). ED50 and ED95 of intrathecal hyperbaric bupivacaine coadministered with opioids for cesarean delivery. ANESTHESIOLOGY, 100(3), 676-682.

Noncardiogenic pulmonary edema and venous air embolus as complications of operative hysteroscopy
Grove, J. J., Shinaman, R. C., & Drover, D. R. (2004). Noncardiogenic pulmonary edema and venous air embolus as complications of operative hysteroscopy. JOURNAL OF CLINICAL ANESTHESIA, 16(1), 48-50.

Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives - Zaleplon, zolpidem and zopiclone
Drover, D. R. (2004). Comparative pharmacokinetics and pharmacodynamics of short-acting hypnosedatives - Zaleplon, zolpidem and zopiclone. CLINICAL PHARMACOKINETICS, 43(4), 227-238.

Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers
Drover, D. R., Angst, M. S., Valle, M., Ramaswamy, B., Naidu, S., & Verotta, D. (2002). Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers. ANESTHESIOLOGY, 97(4), 827-836.

Patient state index - Titration of delivery and recovery from propofol, alfentanil, and nitrous oxide anesthesia
Drover, D. R., Lemmens, H. J., Pierce, E. T., Plourde, G., Loyd, G., & Gugino, L. (2002). Patient state index - Titration of delivery and recovery from propofol, alfentanil, and nitrous oxide anesthesia. ANESTHESIOLOGY, 97(1), 82-89.

Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children
Hammer, G. B., Litalien, C., Wellis, V., & Drover, D. R. (2001). Determination of the median effective concentration (EC50) of propofol during oesophagogastroduodenoscopy in children. PAEDIATRIC ANAESTHESIA, 11(5), 549-553.

Pharmacodynamics of orally administered sustained-release hydromorphone in humans
Angst, M. S., Drover, D. R., Lotsch, J., Ramaswamy, B., Naidu, S., & Stanski, D. R. (2001). Pharmacodynamics of orally administered sustained-release hydromorphone in humans. ANESTHESIOLOGY, 94(1), 63-73.

Pharmacokinetics, pharmacodynamics, and relative pharmacokinetic/pharmacodynamic profiles of zaleplon and zolpidem
Drover, D., Lemmens, H., Naidu, S., Cevallos, W., Darwish, M., & Stanski, D. (2000). Pharmacokinetics, pharmacodynamics, and relative pharmacokinetic/pharmacodynamic profiles of zaleplon and zolpidem. CLINICAL THERAPEUTICS, 22(12), 1443-1461.

Rapacuronium recovery characteristics and infusion requirements during inhalation versus propofol-based anaesthesia
Fu, W., Klein, K. W., White, P. F., Chiu, J. W., Lemmens, H. Jm., & Greenberg, C. P. (2000). Rapacuronium recovery characteristics and infusion requirements during inhalation versus propofol-based anaesthesia. BRITISH JOURNAL OF ANAESTHESIA, 85(2), 302-305.

Orthotopic liver transplantation for carcinoid tumour metastatic to the liver: anesthetic management
Claure, R. E., Drover, D. D., Haddow, G. R., Esquivel, C. O., & Angst, M. S. (2000). Orthotopic liver transplantation for carcinoid tumour metastatic to the liver: anesthetic management. CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 47(4), 334-337.

Population pharmacokinetics of fast release oral diclofenac in healthy volunteers: Relation to pharmacodynamics in an experimental pain model
Lotsch, J., Kettenmann, B., Renner, B., Drover, D., Brune, K., & Kobal, G. (2000). Population pharmacokinetics of fast release oral diclofenac in healthy volunteers: Relation to pharmacodynamics in an experimental pain model. PHARMACEUTICAL RESEARCH, 17(1), 77-84.

Determination of the median effective concentration (EC50) of propofol during esophagogastroduodenoscopy (EGD) in children
Hammer, G. B., Litalien, C., Wellis, V., Drover, D., & Garcia, M. (1999). Determination of the median effective concentration (EC50) of propofol during esophagogastroduodenoscopy (EGD) in children. ANESTHESIOLOGY, 91(3A), U493-U493.

Determination of the EC50 of propofol combined with remifentanil during EGD in children
Hammer, G. B., Litalien, C., Wellis, V., Drover, D., & Garcia, M. (1999). Determination of the EC50 of propofol combined with remifentanil during EGD in children. ANESTHESIOLOGY, 91(3A), U492-U492.

Population pharmacodynamics and pharmacokinetics of remifentanil as a supplement to nitrous oxide anesthesia for elective abdominal surgery
Drover, D. R., & Lemmens, H. Jm. (1998). Population pharmacodynamics and pharmacokinetics of remifentanil as a supplement to nitrous oxide anesthesia for elective abdominal surgery. ANESTHESIOLOGY, 89(4), 869-877.

Determination of the distribution volume that can be used to calculate the intravenous loading dose
Wada, D. R., Drover, D. R., & Lemmens, H. Jm. (1998). Determination of the distribution volume that can be used to calculate the intravenous loading dose. CLINICAL PHARMACOKINETICS, 35(1), 1-7.

DRUG ALLERGIES IN THE SURGICAL POPULATION
Hung, O. R., Bands, C., LANEY, G., Drover, D., Stevens, S., & MacSween, M. (1994). DRUG ALLERGIES IN THE SURGICAL POPULATION. CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 41(12), 1149-1155.

Analysis of trichothecene mycotoxins in human blood by capillary column gas chromatography-ammonia chemical ionization mass spectrometr
D'Agostino, P. A., Provost, L. R., & Drover, D. R. (1986). Analysis of trichothecene mycotoxins in human blood by capillary column gas chromatography-ammonia chemical ionization mass spectrometr. J Chromatogr, 367(1).