Frederick M. Dirbas

Surgical oncologist

Breast surgeon

Breast Cancer Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6004
Learn More About the Clinic Getting Here Make An Appointment

Women's Cancer Center

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6004
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Fellowship: Stanford University School of Medicine (1994) CA

Residency: Stanford University School of Medicine (1992) CA

Residency: Stanford University School of Medicine (1988) CA

Internship: Stanford Hospital and Clinics-Room HC 435 (1986) CA

Medical Education: Columbia University (1985) NY

Fellowship: National Institutes of Health (1989) MD

Board Certification: General Surgery, American Board of Surgery (1994)

MD, Columbia University College of Physicians and Surgeons (1985)

BS with Honors, Stanford University, Chemistry (1981)

Honors & Awards

Best Doctors in America, Best Doctors, Inc. (2014)

Best Doctors in America, Best Doctors, Inc. (2013)

Best Doctors in America, Best Doctors, Inc (2012)

Best Doctors in America, Best Doctors, Inc. (2011)

America's Top Surgeons, Consumers' Research Council of America (2010)

America's Top Oncologists, Consumers' Research Council of America (2009)

Best Doctors in America, Best Doctors, Inc. (2010)

Best Doctors in America, Best Doctors, Inc. (2009)

Star Caregiver Award, Silicon Valley Wellness Foundation (November 12, 2008)

IORT for Breast Cancer (http://www.msnbc.msn.com/id/6503963/ns/nightly_news/), NBC (2004)

Grant Recipient, Vadasz Foundation (2004)

Administrative Appointments

Co-Leader, Breast Cancer Clinical Research Group, Stanford Cancer Center, Stanford University School of Medicine, Stanford Hospital, 2011

Physician Leader, Breast Cancer Clinical Care Program (CCP), Stanford Cancer Center, Stanford University School of Medicine, Stanford Hospital, 2010

Director, Clinical Care Sub-team, Breast Disease Management Group, Stanford Cancer Center, 2006

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Breast Surgical Techniques and Interdisciplinary Management
Frederick M. Dirbas, & Carol Scott-Conner. (2011). Breast Surgical Techniques and Interdisciplinary Management, Springer.

Accelerated Partial Breast Irradiation: Where Do We Stand?
Dirbas, F. M. (2009). Accelerated Partial Breast Irradiation: Where Do We Stand?. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 7(2), 215-225.

Streamlining clinical breast examination
Goodson, W. H., Grissom, N. A., Moore, D. H., & Dirbas, F. M. (2005). Streamlining clinical breast examination. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 97(19), 1476-1477.

The evolution of accelerated, partial breast irradiation as a potential treatment option for women with newly diagnosed breast cancer considering breast conservation
Dirbas, F. M., Jeffrey, S. S., & Goffinet, D. R. (2004). The evolution of accelerated, partial breast irradiation as a potential treatment option for women with newly diagnosed breast cancer considering breast conservation. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 19(6), 673-705.

Defining an optimal role for breast magnetic resonance imaging when evaluating patients otherwise eligible for accelerated partial breast irradiation.
Horst, K. C., Fero, K. E., Ikeda, D. M., Daniel, B. L., & Dirbas, F. M. (2013). Defining an optimal role for breast magnetic resonance imaging when evaluating patients otherwise eligible for accelerated partial breast irradiation. Radiotherapy and oncology , 108(2), 220-225.

Altered local and systemic immune profiles underlie lymph node metastasis in breast cancer patients
Zuckerman, N. S., Yu, H., Simons, D. L., Bhattacharya, N., Carcamo-Cavazos, V., & Lee, P. P. (2013). Altered local and systemic immune profiles underlie lymph node metastasis in breast cancer patients. INTERNATIONAL JOURNAL OF CANCER, 132(11), 2537-2547.

PRC2/EED-EZH2 Complex Is Up-Regulated in Breast Cancer Lymph Node Metastasis Compared to Primary Tumor and Correlates with Tumor Proliferation In Situ
Yu, H., Simons, D. L., Segall, I., Carcamo-Cavazos, V., Schwartz, E. J., & Lee, P. P. (2012). PRC2/EED-EZH2 Complex Is Up-Regulated in Breast Cancer Lymph Node Metastasis Compared to Primary Tumor and Correlates with Tumor Proliferation In Situ. PLOS ONE, 7(12).

A Pilot Cohort Study of the Determinants of Longitudinal Opioid Use After Surgery
Carroll, I., Barelka, P., Wang, C. K. M., Wang, B. M., Gillespie, M. J., & Mackey, S. C. (2012). A Pilot Cohort Study of the Determinants of Longitudinal Opioid Use After Surgery. ANESTHESIA AND ANALGESIA, 115(3), 694-702.

Toward MR-guided high intensity focused ultrasound for presurgical localization: Focused ultrasound lesions in cadaveric breast tissue
Bitton, R. R., Kaye, E., Dirbas, F. M., Daniel, B. L., & Pauly, K. B. (2012). Toward MR-guided high intensity focused ultrasound for presurgical localization: Focused ultrasound lesions in cadaveric breast tissue. JOURNAL OF MAGNETIC RESONANCE IMAGING, 35(5), 1089-1097.

Breast Magnetic Resonance Imaging Alters Patient Selection for Accelerated Partial Breast Irradiation.
Horst, K. C., Ikeda, D. M., Fero, K. E., Daniel, B. L., Goffinet, D. R., & Dirbas, F. M. (2012). Breast Magnetic Resonance Imaging Alters Patient Selection for Accelerated Partial Breast Irradiation. American journal of clinical oncology.

Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
Liu, H., Patel, M. R., Prescher, J. A., Patsialou, A., Qian, D., & Clarke, M. F. (2010). Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(42), 18115-18120.

Freehand MRI-Guided Preoperative Needle Localization of Breast Lesions After MRI-Guided Vacuum-Assisted Core Needle Biopsy Without Marker Placement
van de Ven, S. Mwy., Lin, M. C., Daniel, B. L., Sareen, P., Lipson, J. A., & Ikeda, D. M. (2010). Freehand MRI-Guided Preoperative Needle Localization of Breast Lesions After MRI-Guided Vacuum-Assisted Core Needle Biopsy Without Marker Placement. JOURNAL OF MAGNETIC RESONANCE IMAGING, 32(1), 101-109.

3.0-T MR-Guided Focused Ultrasound for Preoperative Localization of Nonpalpable Breast Lesions: An Initial Experimental Ex Vivo Study
Schmitz, A. C., Van den Bosch, M. Aaj., Rieke, V., Dirbas, F. M., Pauly, K. B., & Daniel, B. L. (2009). 3.0-T MR-Guided Focused Ultrasound for Preoperative Localization of Nonpalpable Breast Lesions: An Initial Experimental Ex Vivo Study. JOURNAL OF MAGNETIC RESONANCE IMAGING, 30(4), 884-889.

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells
Shimono, Y., Zabala, M., Cho, R. W., Lobo, N., Dalerba, P., & Clarke, M. F. (2009). Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells. CELL, 138(3), 592-603.

Impaired interferon signaling is a common immune defect in human cancer
Critchley-Thorne, R. J., Simons, D. L., Yan, N., Miyahira, A. K., Dirbas, F. M., & Lee, P. P. (2009). Impaired interferon signaling is a common immune defect in human cancer. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(22), 9010-9015.

Association of reactive oxygen species levels and radioresistance in cancer stem cells
Diehn, M., Cho, R. W., Lobo, N. A., Kalisky, T., Dorie, M. J., & Clarke, M. F. (2009). Association of reactive oxygen species levels and radioresistance in cancer stem cells. NATURE, 458(7239), 780-U123.

New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
Kohrt, H., Olshen, R., Bermas, H., GOODSON, W., Henry, S., & JEFFREY, S. (2008). New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients. BREAST CANCER RESEARCH AND TREATMENT, 109(3), 588-588.

New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients
Kohrt, H. E., Olshen, R. A., Bermas, H. R., Goodson, W. H., Wood, D. J., & Jeffrey, S. S. (2008). New models and online calculator for predicting non-sentinel lymph node status in sentinel lymph node positive breast cancer patients. BMC CANCER, 8.

Axillary surgery in breast cancer patients
Millet, A., FUSTER, C. A., Lluch, A., & Dirbas, F. (2007). Axillary surgery in breast cancer patients. CLINICAL & TRANSLATIONAL ONCOLOGY, 9(8), 513-520.

Phyllodes tumors of the breast: natural history, diagnosis, and treatment.
Telli, M. L., Horst, K. C., Guardino, A. E., Dirbas, F. M., & Carlson, R. W. (2007). Phyllodes tumors of the breast: natural history, diagnosis, and treatment. Journal of the National Comprehensive Cancer Network , 5(3), 324-330.

Impact of increasing margin around the lumpectomy cavity to define the planning target volume for 3d conformal external beam accelerated partial breast irradiation
Cox, B. W., Horst, K. C., Thornton, S., & Dirbas, F. M. (2007). Impact of increasing margin around the lumpectomy cavity to define the planning target volume for 3d conformal external beam accelerated partial breast irradiation. MEDICAL DOSIMETRY, 32(4), 254-262.

Outcomes of women with metachronous breast and ovarian carcinomas
Liou, W.-S., Hamilton, C. A., Cheung, M. K., Osann, K., Longacre, T. A., & Chan, J. K. (2006). Outcomes of women with metachronous breast and ovarian carcinomas. GYNECOLOGIC ONCOLOGY, 103(1), 190-194.

Predicting non-sentinel lymph node involvement in breast cancer patients.
Kohrt, H. E., Olshen, R. A., Goodson, W. H., Rouse, R. V., Bailey, L., & Jeffrey, S. S. (2006). Predicting non-sentinel lymph node involvement in breast cancer patients. JOURNAL OF CLINICAL ONCOLOGY, 24(18), 10S-10S.

Pathologic correlates of false positive breast magnetic resonance imaging findings: which lesions warrant biopsy?
Langer, S. A., Horst, K. C., Ikeda, D. M., Daniel, B. L., Kong, C. S., & Dirbas, F. M. (2005). Pathologic correlates of false positive breast magnetic resonance imaging findings: which lesions warrant biopsy?. AMERICAN JOURNAL OF SURGERY, 190(4), 633-640.

Rates of reexcision for breast cancer after magnetic resonance imaging-guided bracket wire localization
Wallace, A. M., Daniel, B. L., Jeffrey, S. S., Birdwell, R. L., Nowels, K. W., & Ikeda, D. M. (2005). Rates of reexcision for breast cancer after magnetic resonance imaging-guided bracket wire localization. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 200(4), 527-537.

Breast magnetic resonance imaging alters patient selection for accelerated, partial breast irradiation
Horst, K. C., Ikeda, D. M., Birdwell, R. L., Daniel, B. L., Goffinet, D. R., & Dirbas, F. M. (2005). Breast magnetic resonance imaging alters patient selection for accelerated, partial breast irradiation. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(2), S4-S5.

Magnetic resonance imaging of suspicious breast masses seen on one mammographic view.
Offodile, R. S., Daniel, B. L., Jeffrey, S. S., Wapnir, I., Dirbas, F. M., & Ikeda, D. M. (2004). Magnetic resonance imaging of suspicious breast masses seen on one mammographic view. breast journal, 10(5), 416-422.

Breast magnetic resonance image screening and ductal lavage in women at high genetic risk for breast carcinoma
Hartman, A. R., Daniel, B. L., Kurian, A. W., Mills, M. A., Nowels, K. W., & Plevritis, S. K. (2004). Breast magnetic resonance image screening and ductal lavage in women at high genetic risk for breast carcinoma. CANCER, 100(3), 479-489.

A pilot breast cancer screening trial for women at high inherited risk using clinical breast exam, mammography, breast magnetic resonance imaging, and ductal lavage: updated results after median follow-up of fourteen months.
Kurian, A. W., Daniel, B. L., Mills, M. A., Nowels, K. W., Ford, J. M., & Hartman, A. R. (2004). A pilot breast cancer screening trial for women at high inherited risk using clinical breast exam, mammography, breast magnetic resonance imaging, and ductal lavage: updated results after median follow-up of fourteen months. BREAST CANCER RESEARCH AND TREATMENT, 88, S187-S188.

Results from a pilot breast cancer screening trial using a combination of clincal breast exam, mammography, breast MRI, and ductal lavage in a high-risk population
Hartman, A. R., Kurian, A., Mills, M. A., Daniel, B. L., Ford, J. M., & Plevritis, S. K. (2003). Results from a pilot breast cancer screening trial using a combination of clincal breast exam, mammography, breast MRI, and ductal lavage in a high-risk population. BREAST CANCER RESEARCH AND TREATMENT, 82, S22-S23.

Comprehensive screening using breast MRI and ductal lavage in high-risk women.
Hartman, A. R., Daniel, B. L., Ford, J. M., Chun, N. M., Kingham, K. E., & Plevritis, S. K. (2002). Comprehensive screening using breast MRI and ductal lavage in high-risk women. BREAST CANCER RESEARCH AND TREATMENT, 76, S152-S152.

Clinical management of breast pain: A review
Millet, A. V., & Dirbas, F. M. (2002). Clinical management of breast pain: A review. OBSTETRICAL & GYNECOLOGICAL SURVEY, 57(7), 451-461.

Freehand iMRI-guided large-gauge core needle biopsy: A new minimally invasive technique for diagnosis of enhancing breast lesions
Daniel, B. L., Birdwell, R. L., Butts, K., Nowels, K. W., Ikeda, D. M., & Herfkens, R. J. (2001). Freehand iMRI-guided large-gauge core needle biopsy: A new minimally invasive technique for diagnosis of enhancing breast lesions. JOURNAL OF MAGNETIC RESONANCE IMAGING, 13(6), 896-902.

Locally advanced breast cancer: is surgery necessary?
Favret, A. M., Carlson, R. W., Goffinet, D. R., Jeffrey, S. S., Dirbas, F. M., & Stockdale, F. E. (2001). Locally advanced breast cancer: is surgery necessary?. breast journal, 7(2), 131-137.

Radiofrequency ablation of breast cancer - First report of an emerging technology
Jeffrey, S. S., Birdwell, R. L., Ikeda, D. M., Daniel, B. L., Nowels, K. W., & Griffey, S. M. (1999). Radiofrequency ablation of breast cancer - First report of an emerging technology. ARCHIVES OF SURGERY, 134(10), 1064-1068.

Parathyroid localization with high-resolution ultrasound and technetium Tc 99m sestamibi
Purcell, G. P., Dirbas, F. M., Jeffrey, R. B., Lane, M. J., Desser, T., & Weigel, R. J. (1999). Parathyroid localization with high-resolution ultrasound and technetium Tc 99m sestamibi. ARCHIVES OF SURGERY, 134(8), 824-828.

Perforated jejunal diverticula
Koger, K. E., Shatney, C. H., Dirbas, F. M., & McClenathan, J. H. (1996). Perforated jejunal diverticula. AMERICAN SURGEON, 62(1), 26-29.

HUMANIZED ANTIBODY-DIRECTED TO THE IL-2 RECEPTOR BETA-CHAIN PROLONGS PRIMATE CARDIAC ALLOGRAFT SURVIVAL
TINUBU, S. A., Hakimi, J., KONDAS, J. A., Bailon, P., Familletti, P. C., & Waldmann, T. A. (1994). HUMANIZED ANTIBODY-DIRECTED TO THE IL-2 RECEPTOR BETA-CHAIN PROLONGS PRIMATE CARDIAC ALLOGRAFT SURVIVAL. JOURNAL OF IMMUNOLOGY, 153(9), 4330-4338.

PROLONGATION OF GRAFT-SURVIVAL IN PRIMATE ALLOGRAFT TRANSPLANTATION BY YTTRIUM-90-LABELED ANTI-TAC IN CONJUNCTION WITH GRANULOCYTE COLONY-STIMULATING FACTOR
Parenteau, G. L., Dirbas, F. M., Garmestani, K., Brechbiel, M. W., BUKOWSKI, M. A., & Waldmann, T. A. (1992). PROLONGATION OF GRAFT-SURVIVAL IN PRIMATE ALLOGRAFT TRANSPLANTATION BY YTTRIUM-90-LABELED ANTI-TAC IN CONJUNCTION WITH GRANULOCYTE COLONY-STIMULATING FACTOR. TRANSPLANTATION, 54(6), 963-968.

ANTI-TAC-H, A HUMANIZED ANTIBODY TO THE INTERLEUKIN-2 RECEPTOR, PROLONGS PRIMATE CARDIAC ALLOGRAFT SURVIVAL
Brown, P. S., Parenteau, G. L., Dirbas, F. M., Garsia, R. J., Goldman, C. K., & Waldmann, T. A. (1991). ANTI-TAC-H, A HUMANIZED ANTIBODY TO THE INTERLEUKIN-2 RECEPTOR, PROLONGS PRIMATE CARDIAC ALLOGRAFT SURVIVAL. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 88(7), 2663-2667.

DISSEMINATED CUTANEOUS HERPES-ZOSTER FOLLOWING CARDIAC-SURGERY
Dirbas, F. M., & Swain, J. A. (1990). DISSEMINATED CUTANEOUS HERPES-ZOSTER FOLLOWING CARDIAC-SURGERY. JOURNAL OF CARDIOVASCULAR SURGERY, 31(4), 531-532.

CONTROLLED REPERFUSION FOLLOWING REGIONAL ISCHEMIA
Lazar, H. L., Wei, J., Dirbas, F. M., Haasler, G. B., & Spotnitz, H. M. (1987). CONTROLLED REPERFUSION FOLLOWING REGIONAL ISCHEMIA. ANNALS OF THORACIC SURGERY, 44(4), 350-355.

CONTROLLED REPERFUSION OF REGIONAL ISCHEMIA
Lazar, H. L., Wei, J., Dirbas, F. M., & Spotnitz, H. M. (1983). CONTROLLED REPERFUSION OF REGIONAL ISCHEMIA. SURGICAL FORUM, 34, 257-258.

EXPERIMENTS ON THE ABIOTIC AMPLIFICATION OF OPTICAL-ACTIVITY
Bonner, W. A., Blair, N. E., & Dirbas, F. M. (1981). EXPERIMENTS ON THE ABIOTIC AMPLIFICATION OF OPTICAL-ACTIVITY. ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES, 11(1-2), 119-134.

STEREOSELECTIVE HYDROLYSIS OF LEUCINE OLIGOMERS
Blair, N. E., Dirbas, F. M., & Bonner, W. A. (1981). STEREOSELECTIVE HYDROLYSIS OF LEUCINE OLIGOMERS. TETRAHEDRON, 37(1), 27-29.