Michael B. Fowler, MB, FRCP

Cardiologist

Professor of Medicine (Cardiovascular) at the Stanford University Medical Center

Heart Failure and Cardiomyopathy Clinic

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-5468
Learn More About the Clinic Getting Here Make An Appointment

Heart Transplant Program

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-5468
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Residency: Kent and Canterbury Hospital (1977) England

Medical Education: Charing Cross Hospital Medical School (1975) UK

Residency: Brighton and Sussex Medical School (1979) England

Fellowship: Brighton and Sussex Medical School (1979) England

Fellowship: Stanford University School of Medicine (1984) CA

Internship: New Charing Hosp - London (1976)

Administrative Appointments

Medical Director, CardiomyopathyCenter, Stanford University Medical Center (2001 - Present)

Director, Heart Failure Program, Stanford University Medical Center (2001 - Present)

Professor of Medicine, CardiovascularMedicine, Stanford University Medical Center (1999 - Present)

Assoc. Prof. of Medicine, CardiovascularMedicine, Stanford University Medical Center (1993 - 1999)

Co-Director, Heart Failure Clinic, Stanford University Medical Center (1991 - 2001)

Assistant Professor of Medicine, CardiovascularMedicine, Stanford University Medical Center (1986 - 1993)

Co-Director, Coronary Care Unit, Stanford University Medical Center (1986 - 1991)

Co-Director, Cardiac Advanced Therapies Clinic, Stanford University Medical Center (1984 - 1991)

Clinical Asst. Prof. of Medicine, Stanford University Medical Center (1984 - 1986)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Dipeptidyl Peptidase 4 Inhibition Increases Myocardial Glucose Uptake in Nonischemic Cardiomyopathy
Witteles, R. M., Keu, K. V., Quon, A., Tavana, H., & Fowler, M. B. (2012). Dipeptidyl Peptidase 4 Inhibition Increases Myocardial Glucose Uptake in Nonischemic Cardiomyopathy. JOURNAL OF CARDIAC FAILURE, 18(10), 804-809.

Chemotherapy-Associated Cardiotoxicity: How Often Does it Really Occur and How Can it Be Prevented?
Witteles, R. M., Fowler, M. B., & Telli, M. L. (2011). Chemotherapy-Associated Cardiotoxicity: How Often Does it Really Occur and How Can it Be Prevented?. HEART FAILURE CLINICS, 7(3), 333-?.

Measurement Precision in the Optimization of Cardiac Resynchronization Therapy
Turcott, R. G., Witteles, R. M., Wang, P. J., Vagelos, R. H., Fowler, M. B., & Ashley, E. A. (2010). Measurement Precision in the Optimization of Cardiac Resynchronization Therapy. CIRCULATION-HEART FAILURE, 3(3), 395-404.

Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy.
Kuppahally, S. S., Fowler, M. B., Vagelos, R., Wang, P., Al-Ahmad, A., & Liang, D. (2010). Dyssynchrony Assessment with Tissue Doppler Imaging and Regional Volumetric Analysis by 3D Echocardiography Do Not Predict Long-Term Response to Cardiac Resynchronization Therapy. Cardiology research and practice, 2011, 568918-?.

Worsening of Left Ventricular End-Systolic Volume and Mitral Regurgitation without Increase in Left Ventricular Dyssynchrony on Acute Interruption of Cardiac Resynchronization Therapy
Kuppahally, S. S., Fowler, M. B., Vagelos, R., Wang, P., Al-Ahmad, A., & Liang, D. (2009). Worsening of Left Ventricular End-Systolic Volume and Mitral Regurgitation without Increase in Left Ventricular Dyssynchrony on Acute Interruption of Cardiac Resynchronization Therapy. ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 26(7), 759-765.

Hypertension, heart failure, and beta-adrenergic blocking drugs
Fowler, M. B. (2008). Hypertension, heart failure, and beta-adrenergic blocking drugs. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 52(13), 1073-1075.

Insulin-resistant cardiomyopathy
Witteles, R. M., & Fowler, M. B. (2008). Insulin-resistant cardiomyopathy. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 51(2), 93-102.

Impact of nesiritide on renal function in patients with acute decompensated failure an pre-existing renal dysfunction - A randomized, double-blind, placebo-controlled clinical trial
Witteles, R. M., Kao, D., Christopherson, D., Matsuda, K., Vagelos, R. H., & Fowler, M. B. (2007). Impact of nesiritide on renal function in patients with acute decompensated failure an pre-existing renal dysfunction - A randomized, double-blind, placebo-controlled clinical trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 50(19), 1835-1840.

Outcome in cardiac recipients of donor hearts with increased left ventricular wall thickness
Kuppahally, S. S., Valantine, H. A., Weisshaar, D., Parekh, H., Hung, Y. Y., & Hunt, S. A. (2007). Outcome in cardiac recipients of donor hearts with increased left ventricular wall thickness. AMERICAN JOURNAL OF TRANSPLANTATION, 7(10), 2388-2395.

beta-blocker dosing in community-based treatment of heart failure
Fowler, M. B., Lottes, S. R., Nelson, J. J., Lukas, M. A., Gilbert, E. M., & Franciosa, J. A. (2007). beta-blocker dosing in community-based treatment of heart failure. AMERICAN HEART JOURNAL, 153(6), 1029-1036.

Why do we need to prevent right ventricular pacing?
Tsiperfal, A., Scheibly, K., Fowler, M. B., & Chao, C. (2007). Why do we need to prevent right ventricular pacing?. Progress in cardiovascular nursing, 22(2), 108-109.

The effect of gender on mortality or appropriate shock in patients with nonischemic cardiomyopathy who have implantable cardioverter-defibrillators
Chen, H. A., Hsia, H. H., Vagelos, R., Fowler, M., Wang, P., & Al-Ahmad, A. (2007). The effect of gender on mortality or appropriate shock in patients with nonischemic cardiomyopathy who have implantable cardioverter-defibrillators. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 30(3), 390-394.

Emerging therapies for the management of decompensated heart failure - From bench to bedside
DeGoma, E. M., Vagelos, R. H., Fowler, M. B., & Ashley, E. A. (2006). Emerging therapies for the management of decompensated heart failure - From bench to bedside. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 48(12), 2397-2409.

Cardiomyopathy of insulin resistance.
Witteles, R. M., & Fowler, M. B. (2006). Cardiomyopathy of insulin resistance. Heart failure clinics, 2(1), 13-23.

Care management for low-risk patients with heart failure - A randomized, controlled trial
DeBusk, R. F., Miller, N. H., Parker, K. M., Bandura, A., Kraemer, H. C., & Greenwald, G. (2004). Care management for low-risk patients with heart failure - A randomized, controlled trial. ANNALS OF INTERNAL MEDICINE, 141(8), 606-613.

Insulin resistance in idiopathic dilated cardiomyopathy - A possible etiologic link
Witteles, R. M., Tang, W. Hw., Jamali, A. H., Chu, J. W., Reaven, G. M., & Fowler, M. B. (2004). Insulin resistance in idiopathic dilated cardiomyopathy - A possible etiologic link. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 44(1), 78-81.

Carvedilol prospective randomized cumulative survival (COPERNICUS) trial: Carvedilol in severe heart failure
Fowler, M. B. (2004). Carvedilol prospective randomized cumulative survival (COPERNICUS) trial: Carvedilol in severe heart failure. AMERICAN JOURNAL OF CARDIOLOGY, 93(9A), 35B-39B.

Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction
Chen, M. M., Ashley, E. A., Deng, D. Xf., Tsalenko, A., Deng, A., & Quertermous, T. (2003). Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. CIRCULATION, 108(12), 1432-1439.

Neurohormonal and clinical responses to high- versus low-dose enalapril therapy in chronic heart failure
Tang, W. Hw., Vagelos, R. H., Yee, Y. G., Benedict, C. R., Willson, K., & Fowler, M. B. (2002). Neurohormonal and clinical responses to high- versus low-dose enalapril therapy in chronic heart failure. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 39(1), 70-78.

Beta-adrenergic blocking drugs in severe heart failure.
Fowler, M. (2002). Beta-adrenergic blocking drugs in severe heart failure. Reviews in cardiovascular medicine, 3, S20-6.

Influence of carvedilol on hospitalizations in heart failure: incidence, resource utilization and costs. U.S. Carvedilol Heart Failure Study Group.
Fowler, M. B., Vera-Llonch, M., Oster, G., Bristow, M. R., Cohn, J. N., & Packer, M. (2001). Influence of carvedilol on hospitalizations in heart failure: incidence, resource utilization and costs. U.S. Carvedilol Heart Failure Study Group. Journal of the American College of Cardiology, 37(6), 1692-1699.

The role of angiotensin receptor blockers in the management of chronic heart failure
Jamali, A. H., Tang, W. Hw., Khot, U. N., & Fowler, M. B. (2001). The role of angiotensin receptor blockers in the management of chronic heart failure. ARCHIVES OF INTERNAL MEDICINE, 161(5), 667-672.

Cardiopulmonary exercise testing and prognosis in severe heart failure: 14 mL/kg/min revisited
Myers, J., Gullestad, L., Vagelos, R., Do, D., Bellin, D., & Fowler, M. B. (2000). Cardiopulmonary exercise testing and prognosis in severe heart failure: 14 mL/kg/min revisited. AMERICAN HEART JOURNAL, 139(1), 78-84.

The influence of beta-adrenergic blocking drugs on morbidity and mortality in heart failure
Fowler, M. B. (1999). The influence of beta-adrenergic blocking drugs on morbidity and mortality in heart failure. JOURNAL OF CARDIOVASCULAR RISK, 6(3), 141-144.

Spontaneous postpartum coronary dissection
Lee, F. H., Yeung, A. C., Fowler, M. B., & Fitzgerald, P. J. (1999). Spontaneous postpartum coronary dissection. CIRCULATION, 99(5), 721-721.

beta-blockers in heart failure - Do they improve the quality as well as the quantity of life?
Fowler, M. B. (1998). beta-blockers in heart failure - Do they improve the quality as well as the quantity of life?. EUROPEAN HEART JOURNAL, 19, P17-P25.

Neuropeptide Y receptor 1 (NPY-Y1) expression in human heart failure and heart transplantation
Gullestad, L., Aass, H., Ross, H., Ueland, T., Geiran, O., & Kobilka, B. (1998). Neuropeptide Y receptor 1 (NPY-Y1) expression in human heart failure and heart transplantation. JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 70(1-2), 84-91.

Angiotensin II receptor subtype AT(1) and AT(2) expression after heart transplantation
Gullestad, L., Haywood, G., Aass, H., Ross, H., Yee, G., & Fowler, M. (1998). Angiotensin II receptor subtype AT(1) and AT(2) expression after heart transplantation. CARDIOVASCULAR RESEARCH, 38(2), 340-347.

Use of assumed versus measured oxygen consumption for the determination of cardiac output using the Fick principle
Wolf, A., Pollman, M. J., Trindade, P. T., Fowler, M. B., & Alderman, E. L. (1998). Use of assumed versus measured oxygen consumption for the determination of cardiac output using the Fick principle. CATHETERIZATION AND CARDIOVASCULAR DIAGNOSIS, 43(4), 372-380.

Serial exercise testing and prognosis in selected patients considered for cardiac transplantation
Gullestad, L., Myers, J., Ross, H., Rickenbacher, P., Slauson, S., & Fowler, M. (1998). Serial exercise testing and prognosis in selected patients considered for cardiac transplantation. AMERICAN HEART JOURNAL, 135(2), 221-229.

Effects of beta blockers on symptoms and functional capacity in heart failure.
Fowler, M. B. (1997). Effects of beta blockers on symptoms and functional capacity in heart failure. American journal of cardiology, 80(11A), 55L-58L.

Assessment of left ventricular wall motion abnormalities with the use of color kinesis: A valuable visual and training aid
Lau, Y. S., Puryear, J. V., Gan, S. C., Fowler, M. B., Vagelos, R. H., & Schnittger, I. (1997). Assessment of left ventricular wall motion abnormalities with the use of color kinesis: A valuable visual and training aid. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 10(6), 665-672.

AT(1) and AT(2) angiotensin receptor gene expression in human heart failure
Haywood, G. A., Gullestad, L., Katsuya, T., Hutchinson, H. G., Pratt, R. E., & Fowler, M. B. (1997). AT(1) and AT(2) angiotensin receptor gene expression in human heart failure. CIRCULATION, 95(5), 1201-1206.

Exercise capacity of heart transplant recipients: The importance of chronotropic incompetence
Gullestad, L., Haywood, G., Ross, H., Bjornerheim, R., Geiran, O., & Fowler, M. (1996). Exercise capacity of heart transplant recipients: The importance of chronotropic incompetence. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 15(11), 1075-1083.

Analysis of deaths in patients awaiting heart transplantation: Impact on patient selection criteria
Haywood, G. A., Rickenbacher, P. R., Trindade, P. T., Gullestad, L., Jiang, J. P., & Fowler, M. B. (1996). Analysis of deaths in patients awaiting heart transplantation: Impact on patient selection criteria. HEART, 75(5), 455-462.

Transplant candidates with severe left ventricular dysfunction managed with medical treatment: Characteristics and survival
Rickenbacher, P. R., Trindade, P. T., Haywood, G. A., Vagelos, R. H., Schroeder, J. S., & Fowler, M. B. (1996). Transplant candidates with severe left ventricular dysfunction managed with medical treatment: Characteristics and survival. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 27(5), 1192-1197.

Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle
Lewis, N. P., Tsao, P. S., Rickenbacher, P. R., Xue, C., Johns, R. A., & Fowler, M. B. (1996). Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle. CIRCULATION, 93(4), 720-729.

The relationship of granzyme A and perforin expression to cardiac allograft rejection and dysfunction
Alpert, S., Lewis, N. P., Ross, H., Fowler, M., & Valantine, H. A. (1995). The relationship of granzyme A and perforin expression to cardiac allograft rejection and dysfunction. TRANSPLANTATION, 60(12), 1478-1485.

Selecting candidates for cardiac transplantation. How to assess exclusion criteria and predict who will benefit.
Rickenbacher, P. R., Haywood, G., & Fowler, M. B. (1995). Selecting candidates for cardiac transplantation. How to assess exclusion criteria and predict who will benefit. The Journal of critical illness, 10(3), 199-206.

Spontaneous reversibility of catecholamine-induced cardiotoxicity in rats.
Deisher, T. A., Ginsburg, R., Fowler, M. B., Billingham, M. E., & Bristow, M. R. (1995). Spontaneous reversibility of catecholamine-induced cardiotoxicity in rats. The American journal of cardiovascular pathology, 5(1), 79-88.

INCIDENCE OF MYOCARDITIS IN PERIPARTUM CARDIOMYOPATHY
Rizeq, M. N., Rickenbacher, P. R., Fowler, M. B., & Billingham, M. E. (1994). INCIDENCE OF MYOCARDITIS IN PERIPARTUM CARDIOMYOPATHY. AMERICAN JOURNAL OF CARDIOLOGY, 74(5), 474-477.

LONG-TERM OUTCOME AFTER HEART-TRANSPLANTATION FOR PERIPARTUM CARDIOMYOPATHY
Rickenbacher, P. R., Rizeq, M. N., Hunt, S. A., Billingham, M. E., & Fowler, M. B. (1994). LONG-TERM OUTCOME AFTER HEART-TRANSPLANTATION FOR PERIPARTUM CARDIOMYOPATHY. AMERICAN HEART JOURNAL, 127(5), 1318-1323.

ABNORMALITIES OF PULMONARY-FUNCTION IN PATIENTS WITH CONGESTIVE-HEART-FAILURE, AND REVERSAL WITH IPRATROPIUM BROMIDE
Kindman, L. A., Vagelos, R. H., Willson, K., PRIKAZKY, L., & Fowler, M. (1994). ABNORMALITIES OF PULMONARY-FUNCTION IN PATIENTS WITH CONGESTIVE-HEART-FAILURE, AND REVERSAL WITH IPRATROPIUM BROMIDE. AMERICAN JOURNAL OF CARDIOLOGY, 73(4), 258-262.

PROTECTIVE EFFECT OF CLENTIAZEM AGAINST EPINEPHRINE-INDUCED CARDIAC INJURY IN RATS
Deisher, T. A., Narita, H., ZERA, P., Ginsburg, R., Bristow, M. R., & Hoffman, B. B. (1993). PROTECTIVE EFFECT OF CLENTIAZEM AGAINST EPINEPHRINE-INDUCED CARDIAC INJURY IN RATS. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 266(1), 262-269.

Controlled trials with beta blockers in heart failure: metoprolol as the prototype.
Fowler, M. B. (1993). Controlled trials with beta blockers in heart failure: metoprolol as the prototype. American journal of cardiology, 71(9), 45C-53C.

Beta-blockers in heart failure: potential of carvedilol.
Fowler, M. B. (1993). Beta-blockers in heart failure: potential of carvedilol. Journal of human hypertension, 7, S62-7.

INFLUENCE OF PREOPERATIVE PULMONARY-ARTERY PRESSURE ON MORTALITY AFTER HEART-TRANSPLANTATION - TESTING OF POTENTIAL REVERSIBILITY OF PULMONARY-HYPERTENSION WITH NITROPRUSSIDE IS USEFUL IN DEFINING A HIGH-RISK GROUP
COSTARDJACKLE, A., & Fowler, M. B. (1992). INFLUENCE OF PREOPERATIVE PULMONARY-ARTERY PRESSURE ON MORTALITY AFTER HEART-TRANSPLANTATION - TESTING OF POTENTIAL REVERSIBILITY OF PULMONARY-HYPERTENSION WITH NITROPRUSSIDE IS USEFUL IN DEFINING A HIGH-RISK GROUP. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 19(1), 48-54.

The influence of preoperative patient characteristics on early and late survival following cardiac transplantation.
Costard-Jäckle, A., Hill, I., Schroeder, J. S., & Fowler, M. B. (1991). The influence of preoperative patient characteristics on early and late survival following cardiac transplantation. Circulation, 84(5), III329-37.

CARDIAC ADRENOCEPTORS IN THE FAILING HEART - EFFECT OF INTERVENTION
Fowler, M. B. (1990). CARDIAC ADRENOCEPTORS IN THE FAILING HEART - EFFECT OF INTERVENTION. EUROPEAN HEART JOURNAL, 11, 13-18.

Selection of patients for cardiac transplantation.
Vagelos, R., & Fowler, M. B. (1990). Selection of patients for cardiac transplantation. Cardiology clinics, 8(1), 23-38.

HEMODYNAMIC-EFFECTS OF HIGH-DOSE NALOXONE IN CONGESTIVE HEART-FAILURE
Kindman, L. A., & Fowler, M. B. (1989). HEMODYNAMIC-EFFECTS OF HIGH-DOSE NALOXONE IN CONGESTIVE HEART-FAILURE. AMERICAN JOURNAL OF CARDIOLOGY, 64(8), 542-544.

INCREASED BETA-RECEPTOR DENSITY AND IMPROVED HEMODYNAMIC-RESPONSE TO CATECHOLAMINE STIMULATION DURING LONG-TERM METOPROLOL THERAPY IN HEART-FAILURE FROM DILATED CARDIOMYOPATHY
HEILBRUNN, S. M., Shah, P., Bristow, M. R., Valantine, H. A., Ginsburg, R., & Fowler, M. B. (1989). INCREASED BETA-RECEPTOR DENSITY AND IMPROVED HEMODYNAMIC-RESPONSE TO CATECHOLAMINE STIMULATION DURING LONG-TERM METOPROLOL THERAPY IN HEART-FAILURE FROM DILATED CARDIOMYOPATHY. CIRCULATION, 79(3), 483-490.

HEMODYNAMIC, RENAL AND ENDOCRINE EFFECTS OF ATRIAL NATRIURETIC PEPTIDE INFUSION IN SEVERE HEART-FAILURE
Molina, C. R., Fowler, M. B., MCCRORY, S., Peterson, C., Myers, B. D., & Murad, F. (1988). HEMODYNAMIC, RENAL AND ENDOCRINE EFFECTS OF ATRIAL NATRIURETIC PEPTIDE INFUSION IN SEVERE HEART-FAILURE. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 12(1), 175-186.

ORTHOTOPIC CARDIAC TRANSPLANTATION FOR UNIVENTRICULAR HEART
Macoviak, J. A., Baldwin, J. C., Ginsburg, R., Fowler, M., Valentine, H., & Stinson, E. B. (1988). ORTHOTOPIC CARDIAC TRANSPLANTATION FOR UNIVENTRICULAR HEART. ANNALS OF THORACIC SURGERY, 45(1), 85-86.