Jorg Goronzy

Immunologist

Rheumatologist

Immunology and Rheumatology Clinic

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-723-6961
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Professional Education

Medical Education: RWTH Aachen (1979) Germany

Dr. med., University of Bonn, Medicine (1979)

Fellowship: German Cancer Research Center (1981) Germany

Residency: Hannover Medical School (1984)

Fellowship, Stanford University, Rheumatology (1986)

Dr. med. habil, University of Heidelberg, Medicine (1988)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Understanding immunosenescence to improve responses to vaccines
Goronzy, J. J., & Weyand, C. M. (2013). Understanding immunosenescence to improve responses to vaccines. NATURE IMMUNOLOGY, 14(5), 428-436.

IL-7-and IL-15-Mediated TCR Sensitization Enables T Cell Responses to Self-Antigens
Deshpande, P., Cavanagh, M. M., Le Saux, S., Singh, K., Weyand, C. M., & Goronzy, J. J. (2013). IL-7-and IL-15-Mediated TCR Sensitization Enables T Cell Responses to Self-Antigens. JOURNAL OF IMMUNOLOGY, 190(4), 1416-1423.

The janus head of T cell aging - autoimmunity and immunodeficiency.
Goronzy, J. J., Li, G., Yang, Z., & Weyand, C. M. (2013). The janus head of T cell aging - autoimmunity and immunodeficiency. Frontiers in immunology, 4, 131-?.

Signaling pathways in aged T cells - A reflection of T cell differentiation, cell senescence and host environment
Goronzy, J. J., Li, G., Yu, M., & Weyand, C. M. (2012). Signaling pathways in aged T cells - A reflection of T cell differentiation, cell senescence and host environment. SEMINARS IN IMMUNOLOGY, 24(5), 365-372.

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
Li, G., Yu, M., Lee, W.- woo, Tsang, M., Krishnan, E., & Goronzy, J. J. (2012). Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. NATURE MEDICINE, 18(10), 1518-U113.

The Immunopathology of Giant Cell Arteritis: Diagnostic and Therapeutic Implications
Weyand, C. M., Liao, Y. J., & Goronzy, J. J. (2012). The Immunopathology of Giant Cell Arteritis: Diagnostic and Therapeutic Implications. JOURNAL OF NEURO-OPHTHALMOLOGY, 32(3), 259-265.

CD8(+) CD45RA(+) CCR7(+) FOXP3(+) T Cells with Immunosuppressive Properties: A Novel Subset of Inducible Human Regulatory T Cells
Suzuki, M., Jagger, A. L., Konya, C., Shimojima, Y., Pryshchep, S., & Weyand, C. M. (2012). CD8(+) CD45RA(+) CCR7(+) FOXP3(+) T Cells with Immunosuppressive Properties: A Novel Subset of Inducible Human Regulatory T Cells. JOURNAL OF IMMUNOLOGY, 189(5), 2118-2130.

Chronic inflammation and aging: DNA damage tips the balance
Cavanagh, M. M., Weyand, C. M., & Goronzy, J. J. (2012). Chronic inflammation and aging: DNA damage tips the balance. CURRENT OPINION IN IMMUNOLOGY, 24(4), 488-493.

Immune aging and autoimmunity
Goronzy, J. J., & Weyand, C. M. (2012). Immune aging and autoimmunity. CELLULAR AND MOLECULAR LIFE SCIENCES, 69(10), 1615-1623.

Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age
Yu, M., Li, G., Lee, W.- woo, Yuan, M., Cui, D., & Goronzy, J. J. (2012). Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(15), E879-E888.

Dampened ERK signaling in hematopoietic progenitor cells in rheumatoid arthritis
Colmegna, I., Pryshchep, S., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2012). Dampened ERK signaling in hematopoietic progenitor cells in rheumatoid arthritis. CLINICAL IMMUNOLOGY, 143(1), 73-82.

Mechanisms of immunosenescence: lessons from models of accelerated immune aging
Le Saux, S., Weyand, C. M., & Goronzy, J. J. (2012). Mechanisms of immunosenescence: lessons from models of accelerated immune aging. YEAR IN IMMUNOLOGY, 1247, 69-82.

Telomere dysfunction, autoimmunity and aging.
Hohensinner, P. J., Goronzy, J. J., & Weyand, C. M. (2011). Telomere dysfunction, autoimmunity and aging. Aging and disease, 2(6), 524-537.

Finding Balance: T cell Regulatory Receptor Expression during Aging.
Cavanagh, M. M., Qi, Q., Weyand, C. M., & Goronzy, J. J. (2011). Finding Balance: T cell Regulatory Receptor Expression during Aging. Aging and disease, 2(5), 398-413.

Magnetic Resonance Angiography in Extracranial Giant Cell Arteritis
Koenigkam-Santos, M., Sharma, P., Kalb, B., Oshinski, J. N., Weyand, C. M., & Martin, D. R. (2011). Magnetic Resonance Angiography in Extracranial Giant Cell Arteritis. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 17(6), 306-310.

Role of Increased Guanosine Triphosphate Cyclohydrolase-1 Expression and Tetrahydrobiopterin Levels upon T Cell Activation
Chen, W., Li, L., Brod, T., Saeed, O., Thabet, S., & Harrison, D. G. (2011). Role of Increased Guanosine Triphosphate Cyclohydrolase-1 Expression and Tetrahydrobiopterin Levels upon T Cell Activation. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(16), 13846-13851.

Regulation of T cell receptor signaling by activation-induced zinc influx
Yu, M., Lee, W.- woo, Tomar, D., Pryshchep, S., Czesnikiewicz-Guzik, M., & Goronzy, J. J. (2011). Regulation of T cell receptor signaling by activation-induced zinc influx. JOURNAL OF EXPERIMENTAL MEDICINE, 208(4), 775-785.

Blocking the NOTCH Pathway Inhibits Vascular Inflammation in Large-Vessel Vasculitis
Piggott, K., Deng, J., Warrington, K., Younge, B., Kubo, J. T., & Weyand, C. M. (2011). Blocking the NOTCH Pathway Inhibits Vascular Inflammation in Large-Vessel Vasculitis. CIRCULATION, 123(3), 309-U180.

Giant cell arteritis: immune and vascular aging as disease risk factors
Mohan, S. V., Liao, Y. J., Kim, J. W., Goronzy, J. J., & Weyand, C. M. (2011). Giant cell arteritis: immune and vascular aging as disease risk factors. ARTHRITIS RESEARCH & THERAPY, 13(4).

IFN-gamma and IL-17: the two faces of T-cell pathology in giant cell arteritis
Weyand, C. M., Younge, B. R., & Goronzy, J. J. (2011). IFN-gamma and IL-17: the two faces of T-cell pathology in giant cell arteritis. CURRENT OPINION IN RHEUMATOLOGY, 23(1), 43-49.

Report from the second cytomegalovirus and immunosenescence workshop.
Wills, M., Akbar, A., Beswick, M., Bosch, J. A., Caruso, C., & Pawelec, G. (2011). Report from the second cytomegalovirus and immunosenescence workshop. Immunity & ageing : I & A, 8(1), 10-?.

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension
Vinh, A., Chen, W., Blinder, Y., Weiss, D., Taylor, W. R., & Guzik, T. J. (2010). Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension. CIRCULATION, 122(24), 2529-2537.

DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis
Shao, L., Goronzy, J. J., & Weyand, C. M. (2010). DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis. EMBO MOLECULAR MEDICINE, 2(10), 415-427.

Immune senescence
Aspinall, R., & Goronzy, J. J. (2010). Immune senescence. CURRENT OPINION IN IMMUNOLOGY, 22(4), 497-499.

Immune Aging and Rheumatoid Arthritis
Goronzy, J. J., Shao, L., & Weyand, C. M. (2010). Immune Aging and Rheumatoid Arthritis. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 36(2), 297-?.

Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages
Lamar, D. L., Weyand, C. M., & Goronzy, J. J. (2010). Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages. BLOOD, 115(16), 3278-3286.

Insufficient Deactivation of the Protein Tyrosine Kinase Lck Amplifies T-Cell Responsiveness in Acute Coronary Syndrome
Pryshchep, S., Goronzy, J. J., Parashar, S., & Weyand, C. M. (2010). Insufficient Deactivation of the Protein Tyrosine Kinase Lck Amplifies T-Cell Responsiveness in Acute Coronary Syndrome. CIRCULATION RESEARCH, 106(4), 769-U269.

Th17 and Th1 T-Cell Responses in Giant Cell Arteritis
Deng, J., Younge, B. R., Olshen, R. A., Goronzy, J. J., & Weyand, C. M. (2010). Th17 and Th1 T-Cell Responses in Giant Cell Arteritis. CIRCULATION, 121(7), 906-U107.

Telomeres and Immunological Diseases of Aging
Andrews, N. P., Fujii, H., Goronzy, J. J., & Weyand, C. M. (2010). Telomeres and Immunological Diseases of Aging. GERONTOLOGY, 56(4), 390-403.

ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis
Singh, K., Deshpande, P., Pryshchep, S., Colmegna, I., Liarski, V., & Goronzy, J. J. (2009). ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis. JOURNAL OF IMMUNOLOGY, 183(12), 8258-8267.

Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells
Li, G., Yu, M., Weyand, C. M., & Goronzy, J. J. (2009). Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells. BLOOD, 114(16), 3422-3430.

Rejuvenating the immune system in rheumatoid arthritis
Weyand, C. M., Fujii, H., Shao, L., & Goronzy, J. J. (2009). Rejuvenating the immune system in rheumatoid arthritis. NATURE REVIEWS RHEUMATOLOGY, 5(10), 583-588.

Treating autoimmune disease by targeting CD8(+) T suppressor cells
Konya, C., Goronzy, J. J., & Weyand, C. M. (2009). Treating autoimmune disease by targeting CD8(+) T suppressor cells. EXPERT OPINION ON BIOLOGICAL THERAPY, 9(8), 951-965.

CD28(-) T cells: their role in the age-associated decline of immune function
Weng, N.- ping, Akbar, A. N., & Goronzy, J. (2009). CD28(-) T cells: their role in the age-associated decline of immune function. TRENDS IN IMMUNOLOGY, 30(7), 306-312.

Altered naive and memory CD4+T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome
Zou, J. X., Rollison, D. E., Boulware, D., Chen, D.-T., Sloand, E. M., & Epling-Burnette, P. K. (2009). Altered naive and memory CD4+T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome. LEUKEMIA, 23(7), 1288-1296.

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis
Shao, L., Fujii, H., Colmegna, I., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2009). Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis. JOURNAL OF EXPERIMENTAL MEDICINE, 206(6), 1435-1449.

Telomerase insufficiency in rheumatoid arthritis
Fujii, H., Shao, L., Colmegna, I., Goronzy, J. J., & Weyand, C. M. (2009). Telomerase insufficiency in rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(11), 4360-4365.

Pathogenesis of medium- and large-vessel vasculitis
Weyand, C. M., & Goronzy, J. J. (2009). Pathogenesis of medium- and large-vessel vasculitis. ZEITSCHRIFT FUR RHEUMATOLOGIE, 68(2), 100-?.

Toll-Like Receptors 4 and 5 Induce Distinct Types of Vasculitis
Deng, J., Ma-Krupa, W., Gewirtz, A. T., Younge, B. R., Goronzy, J. J., & Weyand, C. M. (2009). Toll-Like Receptors 4 and 5 Induce Distinct Types of Vasculitis. CIRCULATION RESEARCH, 104(4), 488-U139.

Vascular damage in giant cell arteritis
Piggott, K., Biousse, V., Newman, N. J., Goronzy, J. J., & Weyand, C. M. (2009). Vascular damage in giant cell arteritis. AUTOIMMUNITY, 42(7), 596-604.

Developments in the scientific understanding of rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2009). Developments in the scientific understanding of rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY, 11(5).

Age-Dependent Signature of Metallothionein Expression in Primary CD4 T Cell Responses Is Due to Sustained Zinc Signaling
Lee, W.- woo, Cui, D., Czesnikiewicz-Guzik, M., Vencio, R. Zn., Shmulevich, I., & Goronzy, J. J. (2008). Age-Dependent Signature of Metallothionein Expression in Primary CD4 T Cell Responses Is Due to Sustained Zinc Signaling. REJUVENATION RESEARCH, 11(6), 1001-1011.

Inhibitory CD8(+) T cells in autoimmune disease
Suzuki, M., Konya, C., Goronzy, J. J., & Weyand, C. M. (2008). Inhibitory CD8(+) T cells in autoimmune disease. HUMAN IMMUNOLOGY, 69(11), 781-789.

Is hypertension an immunologic disease?
Harrison, D. G., Guzik, T. J., Goronzy, J., & Weyand, C. (2008). Is hypertension an immunologic disease?. Current cardiology reports, 10(6), 464-469.

T-cell co-stimulatory pathways in autoimmunity
Goronzy, J. J., & Weyand, C. M. (2008). T-cell co-stimulatory pathways in autoimmunity. ARTHRITIS RESEARCH & THERAPY, 10.

T cells in arteritis and atherosclerosis
Weyand, C. M., Younge, B. R., & Goronzy, J. J. (2008). T cells in arteritis and atherosclerosis. CURRENT OPINION IN LIPIDOLOGY, 19(5), 469-477.

Vessel-specific Toll-like receptor profiles in human medium and large arteries
Pryshchep, O., Ma-Krupa, W., Younge, B. R., Goronzy, J. J., & Weyand, C. M. (2008). Vessel-specific Toll-like receptor profiles in human medium and large arteries. CIRCULATION, 118(12), 1276-1284.

Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells
Li, G., Weyand, C. M., & Goronzy, J. J. (2008). Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells. JOURNAL OF LEUKOCYTE BIOLOGY, 84(3), 824-834.

T cell subset-specific susceptibility to aging
Czesnikiewicz-Guzik, M., Lee, W.- woo, Cui, D., Hiruma, Y., Lamar, D. L., & Goronzy, J. J. (2008). T cell subset-specific susceptibility to aging. CLINICAL IMMUNOLOGY, 127(1), 107-118.

TLR-mediated induction of negative regulatory ligands on dendritic cells
Groschel, S., Piggott, K. D., Vaglio, A., Ma-Krupa, W., Singh, K., & Weyand, C. M. (2008). TLR-mediated induction of negative regulatory ligands on dendritic cells. JOURNAL OF MOLECULAR MEDICINE-JMM, 86(4), 443-455.

Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis
Colmegna, I., Diaz-Borjon, A., Fujii, H., Schaefer, L., Goronzy, J. J., & Weyand, C. M. (2008). Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 58(4), 990-1000.

Vessel wall-embedded dendritic cells induce T-Cell autoreactivity and initiate vascular inflammation
Han, J. W., Shimada, K., Ma-Krupa, W., Johnson, T. L., Nerem, R. M., & Weyand, C. M. (2008). Vessel wall-embedded dendritic cells induce T-Cell autoreactivity and initiate vascular inflammation. CIRCULATION RESEARCH, 102(5), 546-553.

Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis
Singh, K., Colmegna, I., He, X., Weyand, C. M., & Goronzy, J. J. (2008). Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 180(3), 1971-1978.

Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and toll-like receptor 4 ligands in the atherosclerotic plaque
Niessner, A., Shin, M. S., Pryshchep, O., Goronzy, J. J., Chaikof, E. L., & Weyand, C. M. (2007). Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and toll-like receptor 4 ligands in the atherosclerotic plaque. CIRCULATION, 116(18), 2043-2052.

Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis
Sawai, H., Park, Y. W., He, X., Goronzy, J. J., & Weyand, C. M. (2007). Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 56(10), 3215-3225.

Role of the T cell in the genesis of angiotensin II-induced hypertension and vascular dysfunction
Guzik, T. J., Hoch, N. E., Brown, K. A., McCann, L. A., Rahman, A., & Harrison, D. G. (2007). Role of the T cell in the genesis of angiotensin II-induced hypertension and vascular dysfunction. JOURNAL OF EXPERIMENTAL MEDICINE, 204(10), 2449-2460.

Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis
Lee, W.- woo, Yang, Z.-Z., Li, G., Weyand, C. A., & Goronzy, J. J. (2007). Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 179(4), 2609-2615.

Aging and T-cell diversity
Goronzy, J. J., Lee, W.- woo, & Weyand, C. M. (2007). Aging and T-cell diversity. EXPERIMENTAL GERONTOLOGY, 42(5), 400-406.

Functional profile of activated dendritic cells in unstable atherosclerotic plaque
Erbel, C., Sato, K., Meyer, F. B., Kopecky, S. L., Frye, R. L., & Weyand, C. M. (2007). Functional profile of activated dendritic cells in unstable atherosclerotic plaque. BASIC RESEARCH IN CARDIOLOGY, 102(2), 123-132.

Occurrence of giant cell arteritis...suddenly.
Younge, B. R., Weyand, C. M., & Goronzy, J. J. (2007). Occurrence of giant cell arteritis...suddenly. Transactions of the American Ophthalmological Society, 105, 141-144.

Immune-mediated mechanisms in atherosclerosis: Prevention and treatment of clinical manifestations
Niessner, A., Goronzy, J. J., & Weyand, C. M. (2007). Immune-mediated mechanisms in atherosclerosis: Prevention and treatment of clinical manifestations. CURRENT PHARMACEUTICAL DESIGN, 13(36), 3701-3710.

Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha
Niessner, A., Sato, K., Chaikof, E. L., Colmegna, I., Goronzy, J. J., & Weyand, C. M. (2006). Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. CIRCULATION, 114(23), 2482-2489.

Treatment of chronic inflammatory diseases with biologic agents: Opportunities and risks for the elderly
Diaz-Borjon, A., Weyand, C. M., & Goronzy, J. J. (2006). Treatment of chronic inflammatory diseases with biologic agents: Opportunities and risks for the elderly. EXPERIMENTAL GERONTOLOGY, 41(12), 1250-1255.

Siravastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo
Niessner, A., Steiner, S., Speidl, W. S., Pleiner, J., Seidinger, D., & Wojta, J. (2006). Siravastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo. ATHEROSCLEROSIS, 189(2), 408-413.

Immunosuppression in atherosclerosis mobilizing the opposition within
Goronzy, J. J., & Weyand, C. M. (2006). Immunosuppression in atherosclerosis mobilizing the opposition within. CIRCULATION, 114(18), 1901-1904.

Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids - A double-blind, placebo-controlled, randomized prospective clinical trial
Mazlumzadeh, M., Hunder, G. G., Easley, K. A., Calamia, K. T., Matteson, E. L., & Goronzy, J. J. (2006). Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids - A double-blind, placebo-controlled, randomized prospective clinical trial. ARTHRITIS AND RHEUMATISM, 54(10), 3310-3318.

Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis
Turesson, C., Schaid, D. J., Weyand, C. M., Jacobsson, L. T., Goronzy, J. J., & Matteson, E. L. (2006). Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 54(9), 2776-2783.

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors
Henel, G., Singh, K., Cui, D., Pryshchep, S., Lee, W.- woo, & Goronzy, J. J. (2006). Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors. BLOOD, 107(11), 4449-4457.

T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome
Pryshchep, S., Sato, K., Goronzy, J. J., & Weyand, C. M. (2006). T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. CIRCULATION RESEARCH, 98(9), 1168-1176.

Pathomechanisms in rheumatoid arthritis - time for a string theory?
Weyand, C. M., & Goronzy, J. J. (2006). Pathomechanisms in rheumatoid arthritis - time for a string theory?. JOURNAL OF CLINICAL INVESTIGATION, 116(4), 869-871.

T-cell-targeted therapies in rheumatoid arthritis
Weyand, C. M., & Goronzy, J. J. (2006). T-cell-targeted therapies in rheumatoid arthritis. NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2(4), 201-210.

Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque
Zhang, X. Y., Niessner, A., Nakajima, T., Ma-Krupa, W., Kopecky, S. L., & Weyand, C. M. (2006). Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. CIRCULATION RESEARCH, 98(4), 524-531.

Telomeres, immune aging and autoimmunity
Goronzy, J. J., Fujii, H., & Weyand, C. M. (2006). Telomeres, immune aging and autoimmunity. EXPERIMENTAL GERONTOLOGY, 41(3), 246-251.

Lymphoma in rheumatoid arthritis: An immune system set up for failure
Weyand, C. M., Goronzy, J. J., & Kurtin, P. J. (2006). Lymphoma in rheumatoid arthritis: An immune system set up for failure. ARTHRITIS AND RHEUMATISM, 54(3), 685-689.

TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque
Sato, K., Niessner, A., Kopecky, S. L., Frye, R. L., Goronzy, J. J., & Weyand, C. M. (2006). TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. JOURNAL OF EXPERIMENTAL MEDICINE, 203(1), 239-250.

Tissue trafficking patterns of effector memory CD4+T cells in rheumatoid arthritis
Zhang, X. Y., Nakajima, T., Goronzy, J. J., & Weyand, C. M. (2005). Tissue trafficking patterns of effector memory CD4+T cells in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(12), 3839-3849.

BLyS and APRIL in rheumatoid arthritis
Seyler, T. M., Park, Y. W., Takemura, S., Bram, R. J., Kurtin, P. J., & Weyand, C. M. (2005). BLyS and APRIL in rheumatoid arthritis. JOURNAL OF CLINICAL INVESTIGATION, 115(11), 3083-3092.

Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis
Bryl, E., Vallejo, A. N., Matteson, E. L., Witkowski, J. M., Weyand, C. M., & Goronzy, J. J. (2005). Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(10), 2996-3003.

T cell development and receptor diversity during aging
Goronzy, J. J., & Weyand, C. M. (2005). T cell development and receptor diversity during aging. CURRENT OPINION IN IMMUNOLOGY, 17(5), 468-475.

Lipopolysaccharide, CD14 and Toll-like receptors: an emerging link between innate immunity and atherosclerotic disease.
Shimada, K., Daida, H., Ma-Krupa, W., Goronzy, J. J., & Weyand, C. M. (2005). Lipopolysaccharide, CD14 and Toll-like receptors: an emerging link between innate immunity and atherosclerotic disease. Future cardiology, 1(5), 657-674.

Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells
Xu, J., Vallejo, A. N., Jiang, Y., Weyand, C. M., & Goronzy, J. J. (2005). Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(25), 24277-24285.

Cell-based immunotherapy with suppressor CD8(+) T cells in rheumatoid arthritis
Davila, E., Kang, Y. M., Park, Y. W., Sawai, H., He, X. W., & Weyand, C. M. (2005). Cell-based immunotherapy with suppressor CD8(+) T cells in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 174(11), 7292-7301.

B cells as a therapeutic target in autoimmune diseases
Park, Y. W., Pryshchep, S., Seyler, T. M., Goronzy, J. J., & Weyand, C. M. (2005). B cells as a therapeutic target in autoimmune diseases. EXPERT OPINION ON THERAPEUTIC TARGETS, 9(3), 431-445.

The influence of age on T cell generation and TCR diversity
Naylor, K., Li, G. J., Vallejo, A. N., Lee, W. W., Koetz, K., & Goronzy, J. J. (2005). The influence of age on T cell generation and TCR diversity. JOURNAL OF IMMUNOLOGY, 174(11), 7446-7452.

B cells in rheumatoid synovitis
Weyand, C. M., Seyler, T., & Goronzy, J. J. (2005). B cells in rheumatoid synovitis. ARTHRITIS RESEARCH & THERAPY, 7, S9-S12.

T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis
Sawai, H., Park, Y. W., Roberson, J., Imai, T., Goronzy, J. J., & Weyand, C. A. (2005). T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(5), 1392-1401.

Rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2005). Rheumatoid arthritis. IMMUNOLOGICAL REVIEWS, 204, 55-73.

Toll-like receptors in giant cell arteritis
Wei, M. K., Kwan, M., Goronzy, J. J., & Weyand, C. M. (2005). Toll-like receptors in giant cell arteritis. CLINICAL IMMUNOLOGY, 115(1), 38-46.

The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis
Turesson, C., Schaid, D. J., Weyand, C. M., Jacobsson, L. Th., Goronzy, J. J., & Matteson, E. L. (2005). The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY, 7(6), R1386-R1393.

Costimulatory pathways in rheumatoid synovitis and T-cell senescence
Goronzy, J. J., Henel, G., Sawai, H., Singh, K., Lee, E. B., & Weyand, C. M. (2005). Costimulatory pathways in rheumatoid synovitis and T-cell senescence. HUMAN IMMUNOLOGY: PATIENT-BASED RESEARCH, 1062, 182-194.

Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study
Warrington, K. J., Kent, P. D., Frye, R. L., Lymp, J. F., Kopecky, S. L., & Weyand, C. M. (2005). Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. ARTHRITIS RESEARCH & THERAPY, 7(5), R984-R991.

Vascular dendritic cells in giant cell arteritis
Weyand, C. M., Ma-Krupa, W., Pryshchep, O., Groschel, S., Bernardino, R., & Goronzy, J. J. (2005). Vascular dendritic cells in giant cell arteritis. HUMAN IMMUNOLOGY: PATIENT-BASED RESEARCH, 1062, 195-208.

Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis
Park, Y. W., Kang, Y. M., Butterfield, J., Detmar, M., Goronzy, J. J., & Weyand, C. M. (2004). Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis. AMERICAN JOURNAL OF PATHOLOGY, 165(6), 2087-2098.

Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms
Snyder, M. R., Nakajima, T., Leibson, P. J., Weyand, C. M., & Goronzy, J. J. (2004). Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms. JOURNAL OF IMMUNOLOGY, 173(6), 3725-3731.

Stem cell aging and autoimmunity in rheumatoid arthritis
Weyand, C. M., & Goronzy, J. Rj. (2004). Stem cell aging and autoimmunity in rheumatoid arthritis. TRENDS IN MOLECULAR MEDICINE, 10(9), 426-433.

VEGF gene polymorphisms and susceptibility to rheumatoid arthritis
Han, S. W., Kim, G. W., Seo, J. S., Kim, S. J., Sa, K. H., & Kang, Y. M. (2004). VEGF gene polymorphisms and susceptibility to rheumatoid arthritis. RHEUMATOLOGY, 43(9), 1173-1177.

Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription
LEWIS, D. E., Merched-Sauvage, M., Goronzy, J. J., Weyand, C. M., & Vallejo, A. N. (2004). Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(28), 29130-29138.

Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis
Braun, A., Takemura, S., Vallejo, A. N., Goronzy, J. J., & Weyand, C. M. (2004). Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 50(7), 2140-2150.

How aggressive should initial therapy for rheumatoid arthritis be? Factors associated with response to 'non-aggressive' DMARD treatment and perspective from a 2-yr open label trial
Matteson, E. L., Weyand, C. M., Fulbright, J. W., Christianson, T. Jh., McClelland, R. L., & Goronzy, J. J. (2004). How aggressive should initial therapy for rheumatoid arthritis be? Factors associated with response to 'non-aggressive' DMARD treatment and perspective from a 2-yr open label trial. RHEUMATOLOGY, 43(5), 619-625.

T-cell regulation in rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2004). T-cell regulation in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY, 16(3), 212-217.

T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection
Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (2004). T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection. TRENDS IN MOLECULAR MEDICINE, 10(3), 119-124.

Biology of T lymphocytes
Vallejo, A. N., Davila, E., Weyand, C. M., & Goronzy, J. J. (2004). Biology of T lymphocytes. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 30(1), 135-?.

Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis
Ma-Krupa, W., Jeon, M. S., Spoerl, S., Tedder, T. E., Goronzy, J. J., & Weyand, C. M. (2004). Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. JOURNAL OF EXPERIMENTAL MEDICINE, 199(2), 173-183.

The double life of NK receptors: stimulation or co-stimulation?
Snyder, M. R., Weyand, C. M., & Goronzy, J. J. (2004). The double life of NK receptors: stimulation or co-stimulation?. TRENDS IN IMMUNOLOGY, 25(1), 25-32.

Prognostic markers of radiographic progression in early rheumatoid arthritis
Goronzy, J. J., Matteson, E. L., Fulbright, J. W., Warrington, K. J., Chang-Miller, A., & Weyand, C. M. (2004). Prognostic markers of radiographic progression in early rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 50(1), 43-54.

HLA-DRB1 haplotype did not affect the medium-term results of total knee arthroplasty in patients with rheumatoid arthritis.
Takemura, S., Toda, Y., Goronzy, J. J., Weyand, C. M., Ogawa, R., & Iida, H. (2004). HLA-DRB1 haplotype did not affect the medium-term results of total knee arthroplasty in patients with rheumatoid arthritis. Modern rheumatology , 14(1), 37-42.

Immunopathways in giant cell arteritis and polymyalgia rheumatica
Weyand, C. M., Ma-Krupa, W., & Goronzy, J. J. (2004). Immunopathways in giant cell arteritis and polymyalgia rheumatica. AUTOIMMUNITY REVIEWS, 3(1), 46-53.

Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages
Schonland, S. O., Lopez, C., Widmann, T., Zimmer, J., Bryl, E., & Weyand, C. M. (2003). Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(23), 13471-13476.

Giant-cell arteritis and polymyalgia rheumatica
Weyand, C. M., & Goronzy, J. J. (2003). Giant-cell arteritis and polymyalgia rheumatica. ANNALS OF INTERNAL MEDICINE, 139(6), 505-515.

Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction
Vallejo, A. N., Yang, H. Y., Klimiuk, P. A., Weyand, C. M., & Goronzy, J. J. (2003). Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction. JOURNAL OF IMMUNOLOGY, 171(4), 1732-1740.

Homeostatic control of T-cell generation in neonates
Schonland, S. O., Zimmer, J. K., Lopez-Benitez, C. M., Widmann, T., Ramin, K. D., & Weyand, C. M. (2003). Homeostatic control of T-cell generation in neonates. BLOOD, 102(4), 1428-1434.

Immunosenescence, autoimmunity, and rheumatoid arthritis
Weyand, C. M., Fulbright, J. W., & Goronzy, J. J. (2003). Immunosenescence, autoimmunity, and rheumatoid arthritis. EXPERIMENTAL GERONTOLOGY, 38(8), 833-841.

De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes
Nakajima, T., Goek, O., Zhang, X. Y., Kopecky, S. L., Frye, R. L., & Weyand, C. M. (2003). De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. CIRCULATION RESEARCH, 93(2), 106-113.

Medium- and large-vessel vasculitis.
Weyand, C. M., & Goronzy, J. J. (2003). Medium- and large-vessel vasculitis. New England journal of medicine, 349(2), 160-169.

The power of the third dimension: tissue architecture and autoimmunity in rheumatoid arthritis
Weyand, C. M., Kang, Y. M., Kurtin, P. J., & Goronzy, J. J. (2003). The power of the third dimension: tissue architecture and autoimmunity in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY, 15(3), 259-266.

CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation
Warrington, K. J., Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (2003). CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation. BLOOD, 101(9), 3543-3549.

Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4(+) T cells
Snyder, M. R., Lucas, M., Vivier, E., Weyand, C. M., & Goronzy, J. J. (2003). Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4(+) T cells. JOURNAL OF EXPERIMENTAL MEDICINE, 197(4), 437-449.

Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation.
Goronzy, J. J., & Weyand, C. M. (2003). Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation. Arthritis research & therapy, 5(5), 225-234.

Ectopic germinal center formation in rheumatoid synovitis
Weyand, C. M., & Goronzy, J. J. (2003). Ectopic germinal center formation in rheumatoid synovitis. IMMUNE MECHANISMS AND DISEASE, 987, 140-149.

B cells as a therapeutic target in autoimmune disease
Goronzy, J. J., & Weyand, C. M. (2003). B cells as a therapeutic target in autoimmune disease. ARTHRITIS RESEARCH & THERAPY, 5(3), 131-135.

Molecular basis for the loss of CD28 expression in senescent T cells
Vallejo, A. N., Bryl, E., Klarskov, K., Naylor, S., Weyand, C. M., & Goronzy, J. J. (2002). Molecular basis for the loss of CD28 expression in senescent T cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(49), 46940-46949.

Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis
Krupa, W. M., Dewan, M., Jeon, M. S., Kurtin, P. J., Younge, B. R., & Weyand, C. M. (2002). Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis. AMERICAN JOURNAL OF PATHOLOGY, 161(5), 1815-1823.

Reactive nitrogen intermediates in giant cell arteritis - Selective nitration of neocapillaries
Borkowski, A., Younge, B. R., Szweda, L., Mock, B., Bjornsson, J., & Weyand, C. M. (2002). Reactive nitrogen intermediates in giant cell arteritis - Selective nitration of neocapillaries. AMERICAN JOURNAL OF PATHOLOGY, 161(1), 115-123.

Premature immunosenescence in rheumatoid arthritis.
Weyand, C. M., & Goronzy, J. J. (2002). Premature immunosenescence in rheumatoid arthritis. journal of rheumatology, 29(6), 1141-1146.

CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis
Kang, Y. M., Zhang, X. Y., Wagner, U. G., Yang, H. Y., Beckenbaugh, R. D., & Weyand, C. M. (2002). CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis. JOURNAL OF EXPERIMENTAL MEDICINE, 195(10), 1325-1336.

Formation of the killer Ig-like receptor repertoire on CD4(+)CD28(null) T cells
Snyder, M. R., Muegge, L. O., Offord, C., O'Fallon, W. M., Bajzer, Z., & Goronzy, J. J. (2002). Formation of the killer Ig-like receptor repertoire on CD4(+)CD28(null) T cells. JOURNAL OF IMMUNOLOGY, 168(8), 3839-3846.

T-cell-mediated lysis of endothelial cells in acute coronary syndromes
Nakajima, T., Schulte, S., Warrington, K. J., Kopecky, S. L., Frye, R. L., & Weyand, C. M. (2002). T-cell-mediated lysis of endothelial cells in acute coronary syndromes. CIRCULATION, 105(5), 570-575.

Therapeutic effects of acetylsalicylic acid in giant cell arteritis
Weyand, C. M., Kaiser, M., Yang, H. Y., Younge, B., & Goronzy, J. J. (2002). Therapeutic effects of acetylsalicylic acid in giant cell arteritis. ARTHRITIS AND RHEUMATISM, 46(2), 457-466.

Cytokines in giant-cell arteritis.
Goronzy, J. J., & Weyand, C. M. (2002). Cytokines in giant-cell arteritis. Cleveland Clinic journal of medicine, 69, SII91-4.

Bi-directional modulation of T cell-dependent antibody production by prostaglandin E-2
He, X. W., Weyand, C. M., Goronzy, J. J., Zhong, W. Y., & Stuart, J. M. (2002). Bi-directional modulation of T cell-dependent antibody production by prostaglandin E-2. INTERNATIONAL IMMUNOLOGY, 14(1), 69-77.

Pathogenic mechanisms in giant cell arteritis.
Weyand, C. M., & Goronzy, J. J. (2002). Pathogenic mechanisms in giant cell arteritis. Cleveland Clinic journal of medicine, 69, SII28-32.

Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
Goronzy, J. J., Fulbright, J. W., Crowson, C. S., Poland, G. A., O'Fallon, W. M., & Weyand, C. M. (2001). Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. JOURNAL OF VIROLOGY, 75(24), 12182-12187.

T cell activation in rheumatoid synovium is B cell dependent
Takemura, S., Klimiuk, P. A., Braun, A., Goronzy, J. J., & Weyand, C. M. (2001). T cell activation in rheumatoid synovium is B cell dependent. JOURNAL OF IMMUNOLOGY, 167(8), 4710-4718.

T-cell immunity in acute coronary syndromes
Weyand, C. M., Goronzy, J. J., Liuzzo, G., Kopecky, S. L., Holmes, D. R., & Frye, R. L. (2001). T-cell immunity in acute coronary syndromes. MAYO CLINIC PROCEEDINGS, 76(10), 1011-1020.

Down-regulation of CD28 expression by TNF-alpha
Bryl, E., Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (2001). Down-regulation of CD28 expression by TNF-alpha. JOURNAL OF IMMUNOLOGY, 167(6), 3231-3238.

Ectopic lymphoid organogenesis - A fast track for autoimmunity
Weyand, C. M., Kurtin, P. J., & Goronzy, J. J. (2001). Ectopic lymphoid organogenesis - A fast track for autoimmunity. AMERICAN JOURNAL OF PATHOLOGY, 159(3), 787-793.

Lymphoid neogenesis in rheumatoid synovitis
Takemura, S., Braun, A., Crowson, C., Kurtin, P. J., Cofield, R. H., & Weyand, C. M. (2001). Lymphoid neogenesis in rheumatoid synovitis. JOURNAL OF IMMUNOLOGY, 167(2), 1072-1080.

Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis
Yen, J. H., Moore, B. E., Nakajima, T., SCHOLL, D., Schaid, D. J., & Goronzy, J. J. (2001). Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis. JOURNAL OF EXPERIMENTAL MEDICINE, 193(10), 1159-1167.

Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2001). Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis. TRENDS IN IMMUNOLOGY, 22(5), 251-255.

Molecular fingerprint of interferon-gamma signaling in unstable angina
Liuzzo, G., Vallejo, A. N., Kopecky, S. L., Frye, R. L., Holmes, D. R., & Weyand, C. M. (2001). Molecular fingerprint of interferon-gamma signaling in unstable angina. CIRCULATION, 103(11), 1509-1514.

Functional disruption of the CD28 gene transcriptional initiator in senescent T cells
Vallejo, A. N., Weyand, C. M., & Goronzy, J. Y. (2001). Functional disruption of the CD28 gene transcriptional initiator in senescent T cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(4), 2565-2570.

T cell homeostasis and autoreactivity in rheumatoid arthritis.
Goronzy, J. J., & Weyand, C. M. (2001). T cell homeostasis and autoreactivity in rheumatoid arthritis. Current directions in autoimmunity, 3, 112-132.

CD4+,CD28-T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems
Warrington, K. J., Takemura, S., Goronzy, J. J., & Weyand, C. M. (2001). CD4+,CD28-T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems. ARTHRITIS AND RHEUMATISM, 44(1), 13-20.

Lymphoid microstructures in rheumatoid synovitis.
Weyand, C. M., Braun, A., Takemura, S., & Goronzy, J. J. (2001). Lymphoid microstructures in rheumatoid synovitis. Current directions in autoimmunity, 3, 168-187.

Clonality and longevity of CD4(+)CD28(null) T cells are associated with defects in apoptotic pathways
Vallejo, A. N., Schirmer, M., Weyand, C. M., & Goronzy, J. J. (2000). Clonality and longevity of CD4(+)CD28(null) T cells are associated with defects in apoptotic pathways. JOURNAL OF IMMUNOLOGY, 165(11), 6301-6307.

Pathogenic principles in giant cell arteritis
Weyand, C. M., & Goronzy, J. J. (2000). Pathogenic principles in giant cell arteritis. INTERNATIONAL JOURNAL OF CARDIOLOGY, 75, S9-S15.

T cell homeostasis in patients with rheumatoid arthritis
Koetz, K., Bryl, E., Spickschen, K., O'Fallon, W. M., Goronzy, J. J., & Weyand, C. M. (2000). T cell homeostasis in patients with rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(16), 9203-?.

Killer cell activating receptors function as costimulatory molecules on CD4(+)CD28(null) T cells clonally expanded in rheumatoid arthritis
NAMEKAWA, T., Snyder, M. R., Yen, J. H., Goehring, B. E., Leibson, P. J., & Goronzy, J. J. (2000). Killer cell activating receptors function as costimulatory molecules on CD4(+)CD28(null) T cells clonally expanded in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 165(2), 1138-1145.

Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes
Liuzzo, G., Goronzy, J. J., Yang, H. Y., Kopecky, S. L., Holmes, D. R., & Weyand, C. M. (2000). Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. CIRCULATION, 101(25), 2883-2888.

Treatment of giant cell arteritis - Interleukin-6 as a biologic marker of disease activity
Weyand, C. M., Fulbright, J. W., Hunder, G. G., Evans, J. M., & Goronzy, J. J. (2000). Treatment of giant cell arteritis - Interleukin-6 as a biologic marker of disease activity. ARTHRITIS AND RHEUMATISM, 43(5), 1041-1048.

Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells
Vallejo, A. N., Mugge, L. O., Klimiuk, P. A., Weyand, C. M., & Goronzy, J. J. (2000). Central role of thrombospondin-1 in the activation and clonal expansion of inflammatory T cells. JOURNAL OF IMMUNOLOGY, 164(6), 2947-2954.

The role of T cells in rheumatoid arthritis.
Weyand, C. M., Bryl, E., & Goronzy, J. J. (2000). The role of T cells in rheumatoid arthritis. Archivum immunologiae et therapiae experimentalis, 48(5), 429-435.

Association of MHC and rheumatoid arthritis HLA polymorphisms in phenotypic variants of rheumatoid arthritis
Weyand, C. M., & Goronzy, J. J. (2000). Association of MHC and rheumatoid arthritis HLA polymorphisms in phenotypic variants of rheumatoid arthritis. ARTHRITIS RESEARCH, 2(3), 212-216.

Cell-cell interactions in synovitis - Interactions between T cells and B cells in rheumatoid arthritis
Weyand, C. M., Goronzy, J. J., Takemura, S., & Kurtin, P. J. (2000). Cell-cell interactions in synovitis - Interactions between T cells and B cells in rheumatoid arthritis. ARTHRITIS RESEARCH, 2(6), 457-463.

[Clinical and genetic heterogeneity of rheumatoid arthritis].
Klimiuk, P. A., Weyand, C. M., Sierakowski, S., & Goronzy, J. J. (2000). [Clinical and genetic heterogeneity of rheumatoid arthritis]. Post?py higieny i medycyny doswiadczalnej, 54(6), 845-853.

Perturbation of the T-cell repertoire in patients with unstable angina
Liuzzo, G., Kopecky, S. L., Frye, R. L., O'Fallon, W. M., Maseri, A., & Weyand, C. M. (1999). Perturbation of the T-cell repertoire in patients with unstable angina. CIRCULATION, 100(21), 2135-2139.

Formation of new vasa vasorum in vasculitis - Production of angiogenic cytokines by multinucleated giant cells
Kaiser, M., Younge, B., Bjornsson, J., Goronzy, J. J., & Weyand, C. M. (1999). Formation of new vasa vasorum in vasculitis - Production of angiogenic cytokines by multinucleated giant cells. AMERICAN JOURNAL OF PATHOLOGY, 155(3), 765-774.

Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence
Vallejo, A. N., Brandes, J. C., Weyand, C. M., & Goronzy, J. J. (1999). Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence. JOURNAL OF IMMUNOLOGY, 162(11), 6572-6579.

Tissue-destructive macrophages in giant cell arteritis
Rittner, H. L., Kaiser, M., Brack, A., Szweda, L. I., Goronzy, J. J., & Weyand, C. M. (1999). Tissue-destructive macrophages in giant cell arteritis. CIRCULATION RESEARCH, 84(9), 1050-1058.

T-cell responses in rheumatoid arthritis: systemic abnormalities-local disease.
Weyand, C. M., & Goronzy, J. J. (1999). T-cell responses in rheumatoid arthritis: systemic abnormalities-local disease. Current opinion in rheumatology, 11(3), 210-217.

Aberrations in the primary T-cell receptor repertoire as a predisposition for synovial inflammation in rheumatoid arthritis
Yang, H. Y., Rittner, H., Weyand, C. M., & Goronzy, J. J. (1999). Aberrations in the primary T-cell receptor repertoire as a predisposition for synovial inflammation in rheumatoid arthritis. JOURNAL OF INVESTIGATIVE MEDICINE, 47(5), 236-245.

IL-16 as an anti-inflammatory cytokine in rheumatoid synovitis
Klimiuk, P. A., Goronzy, J. J., & Weyand, C. M. (1999). IL-16 as an anti-inflammatory cytokine in rheumatoid synovitis. JOURNAL OF IMMUNOLOGY, 162(7), 4293-4299.

Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis
Rittner, H. L., Hafner, V., Klimiuk, P. A., Szweda, L. I., Goronzy, J. J., & Weyand, C. M. (1999). Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. JOURNAL OF CLINICAL INVESTIGATION, 103(7), 1007-1013.

Corticosteroid requirements in polymyalgia rheumatica
Weyand, C. M., Fulbright, J. W., Evans, J. M., Hunder, G. G., & Goronzy, J. J. (1999). Corticosteroid requirements in polymyalgia rheumatica. ARCHIVES OF INTERNAL MEDICINE, 159(6), 577-584.

Production of cytokines and metalloproteinases in rheumatoid synovitis is T cell dependent
Klimiuk, P. A., Yang, H. Y., Goronzy, J. J., & Weyand, C. M. (1999). Production of cytokines and metalloproteinases in rheumatoid synovitis is T cell dependent. CLINICAL IMMUNOLOGY, 90(1), 65-78.

HLA polymorphisms and T cells in rheumatoid arthritis.
Weyand, C. M., & Goronzy, J. J. (1999). HLA polymorphisms and T cells in rheumatoid arthritis. International reviews of immunology, 18(1-2), 37-59.

Functional subsets of CD4 T cells in rheumatoid synovitis
NAMEKAWA, T., Wagner, U. G., Goronzy, J. J., & Weyand, C. M. (1998). Functional subsets of CD4 T cells in rheumatoid synovitis. ARTHRITIS AND RHEUMATISM, 41(12), 2108-2116.

Perturbation of the T cell repertoire in rheumatoid arthritis
Wagner, U. G., Koetz, K., Weyand, C. M., & Goronzy, J. J. (1998). Perturbation of the T cell repertoire in rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 95(24), 14447-14452.

Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4(+)CD28(-) T cells from rheumatoid arthritis patients
Schirmer, M., Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (1998). Resistance to apoptosis and elevated expression of Bcl-2 in clonally expanded CD4(+)CD28(-) T cells from rheumatoid arthritis patients. JOURNAL OF IMMUNOLOGY, 161(2), 1018-1025.

Platelet-derived growth factor, intimal hyperplasia, and ischemic complications in giant cell arteritis
Kaiser, M., Weyand, C. M., Bjornsson, J., & Goronzy, J. J. (1998). Platelet-derived growth factor, intimal hyperplasia, and ischemic complications in giant cell arteritis. ARTHRITIS AND RHEUMATISM, 41(4), 623-633.

Heterogeneity of rheumatoid arthritis: from phenotypes to genotypes
Weyand, C. M., Klimiuk, P. A., & Goronzy, J. J. (1998). Heterogeneity of rheumatoid arthritis: from phenotypes to genotypes. SPRINGER SEMINARS IN IMMUNOPATHOLOGY, 20(1-2), 5-22.

Tissue cytokine patterns distinguish variants of rheumatoid synovitis
Klimiuk, P. A., Goronzy, J. J., Bjornsson, J., Beckenbaugh, R. D., & Weyand, C. M. (1997). Tissue cytokine patterns distinguish variants of rheumatoid synovitis. AMERICAN JOURNAL OF PATHOLOGY, 151(5), 1311-1319.

Glucocorticoid-mediated repression of cytokine gene transcription in human arteritis-SCID chimeras
Brack, A., Rittner, H. L., Younge, B. R., Kaltschmidt, C., Weyand, C. M., & Goronzy, J. J. (1997). Glucocorticoid-mediated repression of cytokine gene transcription in human arteritis-SCID chimeras. JOURNAL OF CLINICAL INVESTIGATION, 99(12), 2842-2850.

Expansion of unusual CD4+ T cells in severe rheumatoid arthritis
Martens, P. B., Goronzy, J. J., Schaid, D., & Weyand, C. M. (1997). Expansion of unusual CD4+ T cells in severe rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 40(6), 1106-1114.

Disease patterns and tissue cytokine profiles in giant cell arteritis
Weyand, C. M., TETZLAFF, N., Bjornsson, J., Brack, A., Younge, B., & Goronzy, J. J. (1997). Disease patterns and tissue cytokine profiles in giant cell arteritis. ARTHRITIS AND RHEUMATISM, 40(1), 19-26.

The inflammatory infiltrate in giant cell arteritis selects against B lymphocytes
MARTINEZTABOADA, V., Brack, A., Hunder, G. G., Goronzy, J. J., & Weyand, C. M. (1996). The inflammatory infiltrate in giant cell arteritis selects against B lymphocytes. JOURNAL OF RHEUMATOLOGY, 23(6), 1011-1014.

CYTOKINES IN POLYMYALGIA AND GIANT-CELL ARTERITIS - RESPONSE
Weyand, C. M., Goronzy, J. J., & Hunder, G. G. (1995). CYTOKINES IN POLYMYALGIA AND GIANT-CELL ARTERITIS - RESPONSE. ANNALS OF INTERNAL MEDICINE, 122(8), 634-634.

TISSUE CYTOKINE PATTERNS IN PATIENTS WITH POLYMYALGIA-RHEUMATICA AND GIANT-CELL ARTERITIS
Weyand, C. M., Hicok, K. C., Hunder, G. G., & Goronzy, J. J. (1994). TISSUE CYTOKINE PATTERNS IN PATIENTS WITH POLYMYALGIA-RHEUMATICA AND GIANT-CELL ARTERITIS. ANNALS OF INTERNAL MEDICINE, 121(7), 484-491.

CORRELATION OF INTERLEUKIN-6 PRODUCTION AND DISEASE-ACTIVITY IN POLYMYALGIA-RHEUMATICA AND GIANT-CELL ARTERITIS
ROCHE, N. E., Fulbright, J. W., Wagner, A. D., Hunder, G. G., Goronzy, J. J., & Weyand, C. M. (1993). CORRELATION OF INTERLEUKIN-6 PRODUCTION AND DISEASE-ACTIVITY IN POLYMYALGIA-RHEUMATICA AND GIANT-CELL ARTERITIS. ARTHRITIS AND RHEUMATISM, 36(9), 1286-1294.

PATHOGENESIS OF GIANT-CELL ARTERITIS
Hunder, G. G., Lie, J. T., Goronzy, J. J., & Weyand, C. M. (1993). PATHOGENESIS OF GIANT-CELL ARTERITIS. ARTHRITIS AND RHEUMATISM, 36(6), 757-761.

THE HLA-DRB1 LOCUS AS A GENETIC COMPONENT IN GIANT-CELL ARTERITIS - MAPPING OF A DISEASE-LINKED SEQUENCE MOTIF TO THE ANTIGEN-BINDING SITE OF THE HLA-DR MOLECULE
Weyand, C. M., Hicok, K. C., Hunder, G. G., & Goronzy, J. J. (1992). THE HLA-DRB1 LOCUS AS A GENETIC COMPONENT IN GIANT-CELL ARTERITIS - MAPPING OF A DISEASE-LINKED SEQUENCE MOTIF TO THE ANTIGEN-BINDING SITE OF THE HLA-DR MOLECULE. JOURNAL OF CLINICAL INVESTIGATION, 90(6), 2355-2361.