Stephen Galli

Professional Education

Fellowship: Massachusetts General Hospital (1979) MA

Medical Education: Harvard Medical School (1973) MA

Residency: Massachusetts General Hospital (1977) MA

Administrative Appointments

Chair, Stanford University School of Medicine - Pathology, 1999

Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation
Ando, T., Matsumoto, K., Namiranian, S., Yamashita, H., Glatthorn, H., & Kawakami, T. (2013). Mast Cells Are Required for Full Expression of Allergen/SEB-Induced Skin Inflammation. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 133(12), 2695-2705.

Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells.
Oka, T., Rios, E. J., Tsai, M., Kalesnikoff, J., & Galli, S. J. (2013). Rapid desensitization induces internalization of antigen-specific IgE on mouse mast cells. journal of allergy and clinical immunology, 132(4), 922-32 e1 16.

PLA2G3 promotes mast cell maturation and function.
Starkl, P., Marichal, T., & Galli, S. J. (2013). PLA2G3 promotes mast cell maturation and function. Nature immunology, 14(6), 527-529.

Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.
Schäfer, B., Piliponsky, A. M., Oka, T., Song, C. H., Gerard, N. P., & Galli, S. J. (2013). Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice. journal of allergy and clinical immunology, 131(2), 541-8 e1 9.

Evidence that mast cells are not required for healing of splinted cutaneous excisional wounds in mice.
Nauta, A. C., Grova, M., Montoro, D. T., Zimmermann, A., Tsai, M., & Longaker, M. T. (2013). Evidence that mast cells are not required for healing of splinted cutaneous excisional wounds in mice. PloS one, 8(3).

New models for analyzing mast cell functions in vivo
Reber, L. L., Marichal, T., & Galli, S. J. (2012). New models for analyzing mast cell functions in vivo. TRENDS IN IMMUNOLOGY, 33(12), 613-625.

Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice
Oka, T., Kalesnikoff, J., Starkl, P., Tsai, M., & Galli, S. J. (2012). Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice. LABORATORY INVESTIGATION, 92(10), 1472-1482.

The Chymase Mouse Mast Cell Protease 4 Degrades TNF, Limits Inflammation, and Promotes Survival in a Model of Sepsis
Piliponsky, A. M., Chen, C.-C., Rios, E. J., Treuting, P. M., Lahiri, A., & Galli, S. J. (2012). The Chymase Mouse Mast Cell Protease 4 Degrades TNF, Limits Inflammation, and Promotes Survival in a Model of Sepsis. AMERICAN JOURNAL OF PATHOLOGY, 181(3), 875-886.

Critical role of P1-Runx1 in mouse basophil development
Mukai, K., Benbarak, M. J., Tachibana, M., Nishida, K., Karasuyama, H., & Galli, S. J. (2012). Critical role of P1-Runx1 in mouse basophil development. BLOOD, 120(1), 76-85.

Modulation of mTOR Effector Phosphoproteins in Blood Basophils from Allergic Patients
Gernez, Y., Tirouvanziam, R., Reshamwala, N., Yu, G., Weldon, B. C., & Nadeau, K. C. (2012). Modulation of mTOR Effector Phosphoproteins in Blood Basophils from Allergic Patients. JOURNAL OF CLINICAL IMMUNOLOGY, 32(3), 565-573.

IgE and mast cells in allergic disease
Galli, S. J., & Tsai, M. (2012). IgE and mast cells in allergic disease. NATURE MEDICINE, 18(5), 693-704.

Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1(fl/fl) mice
Lilla, J. N., Chen, C.-C., Mukai, K., Benbarak, M. J., Franco, C. B., & Galli, S. J. (2011). Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1(fl/fl) mice. BLOOD, 118(26), 6930-6938.

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils
Galli, S. J., Borregaard, N., & Wynn, T. A. (2011). Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils. NATURE IMMUNOLOGY, 12(11), 1035-1044.

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice
Akahoshi, M., Song, C. H., Piliponsky, A. M., Metz, M., Guzzetta, A., & Galli, S. J. (2011). Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice. JOURNAL OF CLINICAL INVESTIGATION, 121(10), 4180-4191.

Identification of an IFN-gamma/mast cell axis in a mouse model of chronic asthma
Yu, M., Eckart, M. R., Morgan, A. A., Mukai, K., Butte, A. J., & Galli, S. J. (2011). Identification of an IFN-gamma/mast cell axis in a mouse model of chronic asthma. JOURNAL OF CLINICAL INVESTIGATION, 121(8), 3133-3143.

Basophil CD203c Levels Are Increased at Baseline and Can Be Used to Monitor Omalizumab Treatment in Subjects with Nut Allergy
Gernez, Y., Tirouvanziam, R., Yu, G., Ghosn, E. Eb., Reshamwala, N., & Nadeau, K. C. (2011). Basophil CD203c Levels Are Increased at Baseline and Can Be Used to Monitor Omalizumab Treatment in Subjects with Nut Allergy. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 154(4), 318-327.

MAST CELLS AND IMMUNOREGULATION/IMMUNOMODULATION
Tsai, M., Grimbaldeston, M., & Galli, S. J. (2011). MAST CELLS AND IMMUNOREGULATION/IMMUNOMODULATION. MAST CELL BIOLOGY: CONTEMPORARY AND EMERGING TOPICS, 716, 186-211.

Antiinflammatory and immunosuppressive functions of mast cells.
Kalesnikoff, J., & Galli, S. J. (2011). Antiinflammatory and immunosuppressive functions of mast cells. Methods in molecular biology (Clifton, N.J.), 677, 207-220.

Thymic Stromal Lymphopoietin Contributes to Myeloid Hyperplasia and Increased Immunoglobulins, But Not Epidermal Hyperplasia, in RabGEF1-Deficient Mice
Tsai, M., Chen, C.-C., Mukai, K., Song, C. H., Thompson, L. J., & Galli, S. J. (2010). Thymic Stromal Lymphopoietin Contributes to Myeloid Hyperplasia and Increased Immunoglobulins, But Not Epidermal Hyperplasia, in RabGEF1-Deficient Mice. AMERICAN JOURNAL OF PATHOLOGY, 177(5), 2411-2420.

Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity
Galli, S. J., & Tsai, M. (2010). Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity. EUROPEAN JOURNAL OF IMMUNOLOGY, 40(7), 1843-1851.

Regulation of secretory granule size by the precise generation and fusion of unit granules
Hammel, I., Lagunoff, D., & Galli, S. J. (2010). Regulation of secretory granule size by the precise generation and fusion of unit granules. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 14(7), 1904-1916.

Distinguishing Mast Cell and Granulocyte Differentiation at the Single-Cell Level
Franco, C. B., Chen, C.-C., Drukker, M., Weissman, I. L., & Galli, S. J. (2010). Distinguishing Mast Cell and Granulocyte Differentiation at the Single-Cell Level. CELL STEM CELL, 6(4), 361-368.

The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice
Itoh, S., Nakae, S., Velotta, J. B., Kosuge, H., Connolly, A., & Fischbein, M. P. (2010). The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 29(4), 401-409.

Evidence that vitamin D-3 promotes mast cell-dependent reduction of chronic UVB-nduced skin pathology in mice
Biggs, L., Yu, C., Fedoric, B., Lopez, A. F., Galli, S. J., & Grimbaldeston, M. A. (2010). Evidence that vitamin D-3 promotes mast cell-dependent reduction of chronic UVB-nduced skin pathology in mice. JOURNAL OF EXPERIMENTAL MEDICINE, 207(3), 455-463.

Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL/6-KitW-sh/W-sh Mice
Piliponsky, A. M., Chen, C.-C., Grimbaldeston, M. A., Burns-Guydish, S. M., Hardy, J., & Galli, S. J. (2010). Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL/6-KitW-sh/W-sh Mice. AMERICAN JOURNAL OF PATHOLOGY, 176(2), 926-938.

Anaphylaxis: mechanisms of mast cell activation.
Kalesnikoff, J., & Galli, S. J. (2010). Anaphylaxis: mechanisms of mast cell activation. Chemical immunology and allergy, 95, 45-66.

Pillars article: fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient w/wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.
Nakano, T., Sonoda, T., Hayashi, C., Yamatodani, A., Kanayama, Y., & Galli, S. J. (2009). Pillars article: fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient w/wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells. Journal of immunology , 183(11), 6863-6881.

Rabaptin-5 regulates receptor expression and functional activation in mast cells
Rios, E. J., Piliponsky, A. M., Ra, C., Kalesnikoff, J., & Galli, S. J. (2008). Rabaptin-5 regulates receptor expression and functional activation in mast cells. BLOOD, 112(10), 4148-4157.

New developments in mast cell biology
Kalesnikoff, J., & Galli, S. J. (2008). New developments in mast cell biology. NATURE IMMUNOLOGY, 9(11), 1215-1223.

IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro
Lantz, C. S., Min, B., Tsai, M., Chatterjea, D., Dranoff, G., & Galli, S. J. (2008). IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro. LABORATORY INVESTIGATION, 88(11), 1134-1142.

Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis
Zabel, B. A., Nakae, S., Zuniga, L., Kim, J.-Y., Ohyama, T., & Butcher, E. C. (2008). Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. JOURNAL OF EXPERIMENTAL MEDICINE, 205(10), 2207-2220.

The development of allergic inflammation
Galli, S. J., Tsai, M., & Piliponsky, A. M. (2008). The development of allergic inflammation. NATURE, 454(7203), 445-454.

Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
Galli, S. J., Grimbaldeston, M., & Tsai, M. (2008). Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. NATURE REVIEWS IMMUNOLOGY, 8(6), 478-U14.

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis
Piliponsky, A. M., Chen, C.-C., Nishimura, T., Metz, M., Rios, E. J., & Galli, S. J. (2008). Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. NATURE MEDICINE, 14(4), 392-398.

Basophils are back!
Galli, S. J., & Franco, C. B. (2008). Basophils are back!. IMMUNITY, 28(4), 495-497.

Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis
Galli, S. J., & Tsai, M. (2008). Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasis. JOURNAL OF DERMATOLOGICAL SCIENCE, 49(1), 7-19.

IL-33 induces IL-13 production by mouse mast cells independently of IgE-Fc epsilon RI signals
Ho, L. H., Ohno, T., Oboki, K., Kajiwara, N., Suto, H., & Nakae, S. (2007). IL-33 induces IL-13 production by mouse mast cells independently of IgE-Fc epsilon RI signals. JOURNAL OF LEUKOCYTE BIOLOGY, 82(6), 1481-1490.

TIM-1 and TIM-3 enhancement of Th2 cytokine poduction by mast cells
Nakae, S., Iikura, M., Suto, H., Akiba, H., Umetsu, D. T., & Galli, S. J. (2007). TIM-1 and TIM-3 enhancement of Th2 cytokine poduction by mast cells. BLOOD, 110(7), 2565-2568.

IL-33 can promote survival, adhesion and cytokine production in human mast cells
Iikura, M., Suto, H., Kajiwara, N., Oboki, K., Ohno, T., & Nakae, S. (2007). IL-33 can promote survival, adhesion and cytokine production in human mast cells. LABORATORY INVESTIGATION, 87(10), 971-978.

Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B
Grimbaldeston, M. A., Nakae, S., Kalesnikoff, J., Tsai, M., & Galli, S. J. (2007). Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. NATURE IMMUNOLOGY, 8(10), 1095-1104.

Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and T(H)2 cytokine production in an asthma model in mice
Nakae, S., Ho, L. H., Yu, M., Monteforte, R., Iikura, M., & Galli, S. J. (2007). Mast cell-derived TNF contributes to airway hyperreactivity, inflammation, and T(H)2 cytokine production in an asthma model in mice. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 120(1), 48-55.

Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cells
Kalesnikoff, J., Rios, E. J., Chen, C.-C., Barbieri, M. A., Tsai, M., & Galli, S. J. (2007). Roles of RabGEF1/Rabex-5 domains in regulating Fc epsilon RI surface expression and Fc epsilon RI-dependent responses in mast cells. BLOOD, 109(12), 5308-5317.

Mast cells in the promotion and limitation of chronic inflammation
Metz, M., Grimbaldeston, M. A., Nakae, S., Piliponsky, A. M., Tsai, M., & Galli, S. J. (2007). Mast cells in the promotion and limitation of chronic inflammation. IMMUNOLOGICAL REVIEWS, 217, 304-328.

Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbumin-challenged OTII mice
Nakae, S., Suto, H., Berry, G. J., & Galli, S. J. (2007). Mast cell-derived TNF can promote Th17 cell-dependent neutrophil recruitment in ovalbumin-challenged OTII mice. BLOOD, 109(9), 3640-3648.

TNF can contribute to multiple features of ovalbumin-induced allergic inflammation of the airways in mice
Nakae, S., Lunderius, C., Ho, L. H., Schafer, B., Tsai, M., & Galli, S. J. (2007). TNF can contribute to multiple features of ovalbumin-induced allergic inflammation of the airways in mice. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 119(3), 680-686.

Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses
Grimbaldeston, M. A., Metz, M., Yu, M., Tsai, M., & Galli, S. J. (2006). Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses. CURRENT OPINION IN IMMUNOLOGY, 18(6), 751-760.

Mast cell-derived tumor necrosis factor can promote nerve fiber elongation in the skin during contact hypersensitivity in mice
Kakurai, M., Monteforte, R., Suto, H., Tsai, M., Nakae, S., & Galli, S. J. (2006). Mast cell-derived tumor necrosis factor can promote nerve fiber elongation in the skin during contact hypersensitivity in mice. AMERICAN JOURNAL OF PATHOLOGY, 169(5), 1713-1721.

Mast cells can enhance resistance to snake and honeybee venoms
Metz, M., Piliponsky, A. M., Chen, C.-C., Lammel, V., Abrink, M., & Galli, S. J. (2006). Mast cells can enhance resistance to snake and honeybee venoms. SCIENCE, 313(5786), 526-530.

Mast cells can promote the development of multiple features of chronic asthma in mice
Yu, M., Tsai, M., Tam, S.-Y., Jones, C., Zehnder, J., & Galli, S. J. (2006). Mast cells can promote the development of multiple features of chronic asthma in mice. JOURNAL OF CLINICAL INVESTIGATION, 116(6), 1633-1641.

Mast cell-associated TNF promotes dendritic cell migration
Suto, H., Nakae, S., Kakurai, M., Sedgwick, J. D., Tsai, M., & Galli, S. J. (2006). Mast cell-associated TNF promotes dendritic cell migration. JOURNAL OF IMMUNOLOGY, 176(7), 4102-4112.

RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells
Kalesnikoff, J., Rios, E. J., Chen, C. C., Nakae, S., Zabel, B. A., & Galli, S. J. (2006). RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(8), 2659-2664.

Mast cells enhance T cell activation: Importance of mast cell costimulatory molecules and secreted TNF
Nakae, S., Suto, H., Iikura, M., Kakurai, M., Sedgwick, J. D., & Galli, S. J. (2006). Mast cells enhance T cell activation: Importance of mast cell costimulatory molecules and secreted TNF. JOURNAL OF IMMUNOLOGY, 176(4), 2238-2248.

Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.
Sampson, H. A., Muñoz-Furlong, A., Campbell, R. L., Adkinson, N. F., Bock, S. A., & Decker, W. W. (2006). Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. journal of allergy and clinical immunology, 117(2), 391-397.

A key regulatory role for histamine in experimental autoimmune encephalomyelitis: Disease exacerbation in histidine decarboxylase-deficient mice
Musio, S., Gallo, B., Scabeni, S., Lapilla, M., Poliani, P. L., & Pedotti, R. (2006). A key regulatory role for histamine in experimental autoimmune encephalomyelitis: Disease exacerbation in histidine decarboxylase-deficient mice. JOURNAL OF IMMUNOLOGY, 176(1), 17-26.

Monomeric IgE enhances human mast cell chemokine production: ILA-4 augments and dexamethasone suppresses the response
Matsuda, K., Piliponsky, A. M., Iikura, M., Nakae, S., Wang, E. W., & Galli, S. J. (2005). Monomeric IgE enhances human mast cell chemokine production: ILA-4 augments and dexamethasone suppresses the response. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 116(6), 1357-1363.

Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation
Gotlib, J., Berube, C., Growney, J. D., Chen, C. C., George, T. I., & Coutre, S. E. (2005). Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation. BLOOD, 106(8), 2865-2870.

Mast cell-deficient W-sash c-kit mutant Kit(W-sh/W-sh) mice as a model for investigating mast cell biology in vivo
Grimbaldeston, M. A., Chen, C. C., Piliponsky, A. M., Tsai, M., Tam, S. Y., & Galli, S. J. (2005). Mast cell-deficient W-sash c-kit mutant Kit(W-sh/W-sh) mice as a model for investigating mast cell biology in vivo. AMERICAN JOURNAL OF PATHOLOGY, 167(3), 835-848.

Identification of mast cell progenitors in adult mice
Chen, C. C., Grimbaldeston, M. A., Tsai, M., Weissman, I. L., & Galli, S. J. (2005). Identification of mast cell progenitors in adult mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(32), 11408-11413.

Mast cells enhance T cell activation: Importance of mast cell-derived TNF
Nakae, S., Suto, H., Kakurai, M., Sedgwick, J. D., Tsai, M., & Galli, S. J. (2005). Mast cells enhance T cell activation: Importance of mast cell-derived TNF. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6467-6472.

Pathogenesis and management of anaphylaxis: Current status and future challenges
Galli, S. J. (2005). Pathogenesis and management of anaphylaxis: Current status and future challenges. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 115(3), 571-574.

Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1,2-dimethylhydrazine-induced intestinal tumors
Wedemeyer, J., & Galli, S. J. (2005). Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1,2-dimethylhydrazine-induced intestinal tumors. LABORATORY INVESTIGATION, 85(3), 388-396.

Symposium on the definition and management of anaphylaxis: Summary report
Sampson, H. A., Munoz-Furlong, A., Bock, A., Schmitt, M., Bass, R., & Camargo, C. A. (2005). Symposium on the definition and management of anaphylaxis: Summary report. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 115(3), 584-591.

Mast cells in the development of adaptive immune responses
Galli, S. J., Nakae, S., & Tsai, M. (2005). Mast cells in the development of adaptive immune responses. NATURE IMMUNOLOGY, 6(2), 135-142.

Mast cells as "tunable" effector and immunoregulatory cells: Recent advances
Galli, S. J., Kalesnikoff, J., Grimbaldeston, M. A., Piliponsky, A. M., Williams, C. Mm., & Tsai, M. (2005). Mast cells as "tunable" effector and immunoregulatory cells: Recent advances. ANNUAL REVIEW OF IMMUNOLOGY, 23, 749-786.

RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation.
Tam, S.-Y., Kalesnikoff, J., Nakae, S., Tsai, M., & Galli, S. J. (2005). RabGEF1, a negative regulator of Ras signalling, mast cell activation and skin inflammation. Novartis Foundation symposium, 271, 115-124.

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity
Maurer, M., Wedemeyer, J., Metz, M., Piliponsky, A. M., Weller, K., & Galli, S. J. (2004). Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. NATURE, 432(7016), 512-516.

RabGEF1 is a negative regulator of mast cell activation and skin inflammation
Tam, S. Y., Tsai, M., Snouwaert, J. N., Kalesnikoff, J., Scherrer, D., & Galli, S. J. (2004). RabGEF1 is a negative regulator of mast cell activation and skin inflammation. NATURE IMMUNOLOGY, 5(8), 844-852.

Immune sensitization in the skin is enhanced by antigen-independent effects of IgE
Bryce, P. J., Miller, M. L., Miyajima, I., Tsai, M., GALLI, S. J., & Oettgen, H. C. (2004). Immune sensitization in the skin is enhanced by antigen-independent effects of IgE. IMMUNITY, 20(4), 381-392.

Chair's introduction. Anaphylaxis.
Galli, S. J. (2004). Chair's introduction. Anaphylaxis. Novartis Foundation symposium, 257, 1-5.

Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the Fc epsilon RI
Kitaura, J., Song, J. M., Tsai, M., Asai, K., Maeda-Yamamoto, M., & Kawakami, T. (2003). Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the Fc epsilon RI. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(22), 12911-12916.

Involvement of both 'allergic' and "autoimmune' mechanisms in EAE, MS and other autoimmune diseases
Pedotti, R., De Voss, J. J., Steinman, L., & GALLI, S. J. (2003). Involvement of both 'allergic' and "autoimmune' mechanisms in EAE, MS and other autoimmune diseases. TRENDS IN IMMUNOLOGY, 24(9), 479-484.

Identification of A(3) receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice
Tilley, S. L., Tsai, M., Williams, C. M., Wang, Z. S., Erikson, C. J., & Koller, B. H. (2003). Identification of A(3) receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice. JOURNAL OF IMMUNOLOGY, 171(1), 331-337.

Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus.
Pedotti, R., Sanna, M., Tsai, M., DeVoss, J., Steinman, L., & Galli, S. J. (2003). Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus. BMC immunology, 4, 2-?.

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination
Pedotti, R., DeVoss, J. J., Youssef, S., Mitchell, D., Wedemeyer, J., & Steinman, L. (2003). Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(4), 1867-1872.

Regulation of mast-cell and basophil function and survival by IgE
Kawakami, T., & Galli, S. J. (2002). Regulation of mast-cell and basophil function and survival by IgE. NATURE REVIEWS IMMUNOLOGY, 2(10), 773-786.

Probing the roles of mast cells and basophils in natural and acquired immunity, physiology and disease.
Marone, G., Galli, S. J., & Kitamura, Y. (2002). Probing the roles of mast cells and basophils in natural and acquired immunity, physiology and disease. Trends in immunology, 23(9), 425-427.

Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11.
Sayama, K., Diehn, M., Matsuda, K., Lunderius, C., Tsai, M., & Galli, S. J. (2002). Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11. BMC immunology, 3, 5-?.

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
Lock, C., Hermans, G., Pedotti, R., Brendolan, A., Schadt, E., & Steinman, L. (2002). Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. NATURE MEDICINE, 8(5), 500-508.

Regulation of mast cell survival by IgE
Asai, K., Kitaura, J., Kawakami, Y., Yamagata, N., Tsai, M., & Kawakami, T. (2001). Regulation of mast cell survival by IgE. IMMUNITY, 14(6), 791-800.

An unexpected version of horror autotoxicus: anaphylactic shock to a self peptide
Pedotti, R., Mitchell, D., Wedemeyer, J., Karpuj, M., Chabas, D., & Steinman, L. (2001). An unexpected version of horror autotoxicus: anaphylactic shock to a self peptide. NATURE IMMUNOLOGY, 2(3), 216-222.

Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice
Williams, C. Mm., & Galli, S. J. (2000). Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. JOURNAL OF EXPERIMENTAL MEDICINE, 192(3), 455-462.

In vivo immunological function of mast cells derived from embryonic stem cells: An approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo
Tsai, M., Wedemeyer, J., Ganiatsas, S., Tam, S. Y., Zon, L. I., & GALLI, S. J. (2000). In vivo immunological function of mast cells derived from embryonic stem cells: An approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(16), 9186-9190.

A role for Bax in the regulation of apoptosis in mouse mast cells
Maurer, M., Tsai, M., Metz, M., Fish, S., Korsmeyer, S. J., & GALLI, S. J. (2000). A role for Bax in the regulation of apoptosis in mouse mast cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 114(6), 1205-1206.

The diverse potential effector and immunoregulatory roles of mast cells in allergic disease
Williams, C. Mm., & GALLI, S. J. (2000). The diverse potential effector and immunoregulatory roles of mast cells in allergic disease. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 105(5), 847-859.

Mast cells and basophils
Galli, S. J. (2000). Mast cells and basophils. CURRENT OPINION IN HEMATOLOGY, 7(1), 32-39.

Mast-cell heparin demystified.
Zehnder, J. L., & GALLI, S. J. (1999). Mast-cell heparin demystified. Nature, 400(6746), 714-715.

IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: Synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release
Yamaguchi, M., Sayama, K., Yano, K., Lantz, C. S., Noben-Trauth, N., & GALLI, S. J. (1999). IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: Synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release. JOURNAL OF IMMUNOLOGY, 162(9), 5455-5465.

Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kit
London, C. A., GALLI, S. J., Yuuki, T., Hu, Z. Q., Helfand, S. C., & Geissler, E. N. (1999). Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kit. EXPERIMENTAL HEMATOLOGY, 27(4), 689-697.

Mast cells as sentinels of innate immunity
Galli, S. J., Maurer, M., & Lantz, C. S. (1999). Mast cells as sentinels of innate immunity. CURRENT OPINION IN IMMUNOLOGY, 11(1), 53-59.

The c-kit ligand, stem cell factor, can enhance innate immunity through effects on mast cells
Maurer, M., Echtenacher, B., Hultner, L., Kollias, G., Mannel, D. N., & Galli, S. J. (1998). The c-kit ligand, stem cell factor, can enhance innate immunity through effects on mast cells. JOURNAL OF EXPERIMENTAL MEDICINE, 188(12), 2343-2348.

Mast cells can secrete vascular permeability factor vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of Fc epsilon receptor I expression
Boesiger, J., Tsai, M., Maurer, M., Yamaguchi, M., BROWN, L. F., & Galli, S. J. (1998). Mast cells can secrete vascular permeability factor vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of Fc epsilon receptor I expression. JOURNAL OF EXPERIMENTAL MEDICINE, 188(6), 1135-1145.

Involvement of Bruton's tyrosine kinase in Fc epsilon RI-dependent mast cell degranulation and cytokine production
Hata, D., Kawakami, Y., Inagaki, N., Lantz, C. S., Kitamura, T., & Kawakami, T. (1998). Involvement of Bruton's tyrosine kinase in Fc epsilon RI-dependent mast cell degranulation and cytokine production. JOURNAL OF EXPERIMENTAL MEDICINE, 187(8), 1235-1247.

P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin
de Mora, F., Williams, C. Mm., Frenette, P. S., Wagner, D. D., HYNES, R. O., & GALLI, S. J. (1998). P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin. LABORATORY INVESTIGATION, 78(4), 497-505.

Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites
Lantz, C. S., Boesiger, J., Song, C. H., MACH, N., Kobayashi, T., & GALLI, S. J. (1998). Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites. NATURE, 392(6671), 90-93.

Involvement of interleukin-3 in delayed-type hypersensitivity
MACH, N., Lantz, C. S., GALLI, S. J., Reznikoff, G., Mihm, M., & Dranoff, G. (1998). Involvement of interleukin-3 in delayed-type hypersensitivity. BLOOD, 91(3), 778-783.

Impaired mast cell-dependent natural immunity in complement C3-deficient mice
Prodeus, A. P., Zhou, X. N., Maurer, M., GALLI, S. J., & Carroll, M. C. (1997). Impaired mast cell-dependent natural immunity in complement C3-deficient mice. NATURE, 390(6656), 172-175.

Expression of functional TrkA receptor tyrosine kinase in the HMC-1 human mast cell line and in human mast cells
Tam, S. Y., Tsai, M., Yamaguchi, M., Yano, K., Butterfield, J. H., & GALLI, S. J. (1997). Expression of functional TrkA receptor tyrosine kinase in the HMC-1 human mast cell line and in human mast cells. BLOOD, 90(5), 1807-1820.

Complexity and redundancy in the pathogenesis of asthma: Reassessing the roles of mast cells and T cells
GALLI, S. J. (1997). Complexity and redundancy in the pathogenesis of asthma: Reassessing the roles of mast cells and T cells. JOURNAL OF EXPERIMENTAL MEDICINE, 186(3), 343-347.

The Paul Kallos Memorial Lecture. The mast cell: a versatile effector cell for a challenging world.
GALLI, S. J. (1997). The Paul Kallos Memorial Lecture. The mast cell: a versatile effector cell for a challenging world. International archives of allergy and immunology, 113(1-3), 14-22.

Differential release of mast cell interleukin-6 via c-kit
Gagari, E., Tsai, M., Lantz, C. S., FOX, L. G., & GALLI, S. J. (1997). Differential release of mast cell interleukin-6 via c-kit. BLOOD, 89(8), 2654-2663.

IgE regulates mouse basophil Fc epsilon RI expression in vivo
Lantz, C. S., Yamaguchi, M., Oettgen, H. C., Katona, I. M., Miyajima, I., & GALLI, S. J. (1997). IgE regulates mouse basophil Fc epsilon RI expression in vivo. JOURNAL OF IMMUNOLOGY, 158(6), 2517-2521.

Absence of Fc(epsilon)RI alpha chain results in upregulation of Fc gamma RIII-dependent mast cell degranulation and anaphylaxis - Evidence of competition between Fc(epsilon)RI and Fc gamma RIII for limiting amounts of FcR beta and gamma chains
Dombrowicz, D., Flamand, V., Miyajima, I., Ravetch, J. V., GALLI, S. J., & Kinet, J. P. (1997). Absence of Fc(epsilon)RI alpha chain results in upregulation of Fc gamma RIII-dependent mast cell degranulation and anaphylaxis - Evidence of competition between Fc(epsilon)RI and Fc gamma RIII for limiting amounts of FcR beta and gamma chains. JOURNAL OF CLINICAL INVESTIGATION, 99(5), 915-925.

Systemic anaphylaxis in the mouse can be mediated largely through IgG, and Fc gamma RIII - Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG(1)-dependent passive anaphylaxis
Miyajima, I., Dombrowicz, D., Martin, T. R., Ravetch, J. V., Kinet, J. P., & GALLI, S. J. (1997). Systemic anaphylaxis in the mouse can be mediated largely through IgG, and Fc gamma RIII - Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG(1)-dependent passive anaphylaxis. JOURNAL OF CLINICAL INVESTIGATION, 99(5), 901-914.

IgE enhances mouse mast cell Fc epsilon RI expression in vitro and in vivo: Evidence for a novel amplification mechanism in IgE-dependent reactions
Yamaguchi, M., Lantz, C. S., Oettgen, H. C., Katona, I. M., Fleming, T., & GALLI, S. J. (1997). IgE enhances mouse mast cell Fc epsilon RI expression in vitro and in vivo: Evidence for a novel amplification mechanism in IgE-dependent reactions. JOURNAL OF EXPERIMENTAL MEDICINE, 185(4), 663-672.

Earthquakes: Slow down for safety
Segall, P. (1996). Earthquakes: Slow down for safety. NATURE, 383(6595), 21-22.

Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase SHP1
Lorenz, U., Bergemann, A. D., Steinberg, H. N., Flanagan, J. G., Li, X. T., & Neel, B. G. (1996). Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase SHP1. JOURNAL OF EXPERIMENTAL MEDICINE, 184(3), 1111-1126.

Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo
Costa, J. J., Demetri, G. D., Harrist, T. J., Dvorak, A. M., Hayes, D. F., & GALLI, S. J. (1996). Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo. JOURNAL OF EXPERIMENTAL MEDICINE, 183(6), 2681-2686.

Identification of a committed precursor for the mast cell lineage
Rodewald, H. R., Dessing, M., Dvorak, A. M., & GALLI, S. J. (1996). Identification of a committed precursor for the mast cell lineage. SCIENCE, 271(5250), 818-822.

STEM-CELL FACTOR CONTRIBUTES TO INTESTINAL MUCOSAL MAST-CELL HYPERPLASIA IN RATS INFECTED WITH NIPPOSTRONGYLUS-BRASILIENSIS OR TRICHINELLA-SPIRALIS, BUT ANTI-STEM CELL FACTOR TREATMENT DECREASES PARASITE EGG-PRODUCTION DURING N-BRASILIENSIS INFECTION
Newlands, G. Fj., Miller, H. Rp., MacKellar, A., & GALLI, S. J. (1995). STEM-CELL FACTOR CONTRIBUTES TO INTESTINAL MUCOSAL MAST-CELL HYPERPLASIA IN RATS INFECTED WITH NIPPOSTRONGYLUS-BRASILIENSIS OR TRICHINELLA-SPIRALIS, BUT ANTI-STEM CELL FACTOR TREATMENT DECREASES PARASITE EGG-PRODUCTION DURING N-BRASILIENSIS INFECTION. BLOOD, 86(5), 1968-1976.

DEXAMETHASONE OR CYCLOSPORINE-A SUPPRESS MAST CELL-LEUKOCYTE CYTOKINE CASCADES - MULTIPLE MECHANISMS OF INHIBITION OF IGE-DEPENDENT AND MAST-CELL-DEPENDENT CUTANEOUS INFLAMMATION IN THE MOUSE
Wershil, B. K., Furuta, G. T., Lavigne, J. A., Choudhury, A. R., Wang, Z. S., & GALLI, S. J. (1995). DEXAMETHASONE OR CYCLOSPORINE-A SUPPRESS MAST CELL-LEUKOCYTE CYTOKINE CASCADES - MULTIPLE MECHANISMS OF INHIBITION OF IGE-DEPENDENT AND MAST-CELL-DEPENDENT CUTANEOUS INFLAMMATION IN THE MOUSE. JOURNAL OF IMMUNOLOGY, 154(3), 1391-1398.

PROMOTION OF MOUSE FIBROBLAST COLLAGEN GENE-EXPRESSION BY MAST-CELLS STIMULATED VIA THE FC(EPSILON)RI - ROLE FOR MAST CELL-DERIVED TRANSFORMING GROWTH-FACTOR-BETA AND TUMOR-NECROSIS-FACTOR-ALPHA
Gordon, J. R., & GALLI, S. J. (1994). PROMOTION OF MOUSE FIBROBLAST COLLAGEN GENE-EXPRESSION BY MAST-CELLS STIMULATED VIA THE FC(EPSILON)RI - ROLE FOR MAST CELL-DERIVED TRANSFORMING GROWTH-FACTOR-BETA AND TUMOR-NECROSIS-FACTOR-ALPHA. JOURNAL OF EXPERIMENTAL MEDICINE, 180(6), 2027-2037.

CYTOPLASMIC GRANULE FORMATION IN MOUSE PANCREATIC ACINAR-CELLS - EVIDENCE FOR FORMATION OF IMMATURE GRANULES (CONDENSING VACUOLES) BY AGGREGATION AND FUSION OF PROGRANULES OF UNIT SIZE, AND FOR REDUCTIONS IN MEMBRANE-SURFACE AREA AND IMMATURE GRANULE VOLUME DURING GRANULE MATURATION
LEW, S., Hammel, I., & GALLI, S. J. (1994). CYTOPLASMIC GRANULE FORMATION IN MOUSE PANCREATIC ACINAR-CELLS - EVIDENCE FOR FORMATION OF IMMATURE GRANULES (CONDENSING VACUOLES) BY AGGREGATION AND FUSION OF PROGRANULES OF UNIT SIZE, AND FOR REDUCTIONS IN MEMBRANE-SURFACE AREA AND IMMATURE GRANULE VOLUME DURING GRANULE MATURATION. CELL AND TISSUE RESEARCH, 278(2), 327-336.

PIECEMEAL DEGRANULATION OF MAST-CELLS IN THE INFLAMMATORY EYELID LESIONS OF INTERLEUKIN-4 TRANSGENIC MICE - EVIDENCE OF MAST-CELL HISTAMINE-RELEASE IN-VIVO BY DIAMINE OXIDASE-GOLD ENZYME-AFFINITY ULTRASTRUCTURAL CYTOCHEMISTRY
Dvorak, A. M., Tepper, R. I., Weller, P. F., Morgan, E. S., ESTRELLA, P., & GALLI, S. J. (1994). PIECEMEAL DEGRANULATION OF MAST-CELLS IN THE INFLAMMATORY EYELID LESIONS OF INTERLEUKIN-4 TRANSGENIC MICE - EVIDENCE OF MAST-CELL HISTAMINE-RELEASE IN-VIVO BY DIAMINE OXIDASE-GOLD ENZYME-AFFINITY ULTRASTRUCTURAL CYTOCHEMISTRY. BLOOD, 83(12), 3600-3612.

MAST-CELLS AUGMENT LESION SIZE AND PERSISTENCE DURING EXPERIMENTAL LEISHMANIA-MAJOR INFECTION IN THE MOUSE
Wershil, B. K., Theodos, C. M., GALLI, S. J., & Titus, R. G. (1994). MAST-CELLS AUGMENT LESION SIZE AND PERSISTENCE DURING EXPERIMENTAL LEISHMANIA-MAJOR INFECTION IN THE MOUSE. JOURNAL OF IMMUNOLOGY, 152(9), 4563-4571.

IDENTIFICATION OF IGE-BEARING CELLS IN THE LATE-PHASE RESPONSE TO ANTIGEN IN THE LUNG AS BASOPHILS
Guo, C. B., Liu, M. C., GALLI, S. J., Bochner, B. S., KAGEYSOBOTKA, A., & LICHTENSTEIN, L. M. (1994). IDENTIFICATION OF IGE-BEARING CELLS IN THE LATE-PHASE RESPONSE TO ANTIGEN IN THE LUNG AS BASOPHILS. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 10(4), 384-390.

THE KIT-LIGAND, STEM-CELL FACTOR
GALLI, S. J., Zsebo, K. M., & Geissler, E. N. (1994). THE KIT-LIGAND, STEM-CELL FACTOR. ADVANCES IN IMMUNOLOGY, VOL 55, 55, 1-96.

EFFECTS OF INTERLEUKIN-3 WITH OR WITHOUT THE C-KIT LIGAND, STEM-CELL FACTOR, ON THE SURVIVAL AND CYTOPLASMIC GRANULE FORMATION OF MOUSE BASOPHILS AND MAST-CELLS IN-VITRO
Dvorak, A. M., SEDER, R. A., PAUL, W. E., Morgan, E. S., & GALLI, S. J. (1994). EFFECTS OF INTERLEUKIN-3 WITH OR WITHOUT THE C-KIT LIGAND, STEM-CELL FACTOR, ON THE SURVIVAL AND CYTOPLASMIC GRANULE FORMATION OF MOUSE BASOPHILS AND MAST-CELLS IN-VITRO. AMERICAN JOURNAL OF PATHOLOGY, 144(1), 160-170.

EFFECTS OF CHRONIC TREATMENT WITH THE C-KIT LIGAND, STEM-CELL FACTOR, ON IMMUNOGLOBULIN-E DEPENDENT ANAPHYLAXIS IN MICE - GENETICALLY MAST-CELL DEFICIENT SL/SL(D) MICE ACQUIRE ANAPHYLACTIC RESPONSIVENESS, BUT THE CONGENIC NORMAL MICE DO NOT EXHIBIT AUGMENTED RESPONSES
Ando, A., Martin, T. R., & GALLI, S. J. (1993). EFFECTS OF CHRONIC TREATMENT WITH THE C-KIT LIGAND, STEM-CELL FACTOR, ON IMMUNOGLOBULIN-E DEPENDENT ANAPHYLAXIS IN MICE - GENETICALLY MAST-CELL DEFICIENT SL/SL(D) MICE ACQUIRE ANAPHYLACTIC RESPONSIVENESS, BUT THE CONGENIC NORMAL MICE DO NOT EXHIBIT AUGMENTED RESPONSES. JOURNAL OF CLINICAL INVESTIGATION, 92(4), 1639-1649.

MAST-CELLS CONTRIBUTE TO THE CHANGES IN HEART-RATE, BUT NOT HYPOTENSION OR DEATH, ASSOCIATED WITH ACTIVE ANAPHYLAXIS IN MICE
Martin, T. R., Ando, A., Takeishi, T., Katona, I. M., Drazen, J. M., & GALLI, S. J. (1993). MAST-CELLS CONTRIBUTE TO THE CHANGES IN HEART-RATE, BUT NOT HYPOTENSION OR DEATH, ASSOCIATED WITH ACTIVE ANAPHYLAXIS IN MICE. JOURNAL OF IMMUNOLOGY, 151(1), 367-376.

HUMAN EOSINOPHILS CAN EXPRESS THE CYTOKINES TUMOR-NECROSIS-FACTOR-ALPHA AND MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA
Costa, J. J., Matossian, K., Resnick, M. B., Beil, W. J., Wong, D. Tw., & GALLI, S. J. (1993). HUMAN EOSINOPHILS CAN EXPRESS THE CYTOKINES TUMOR-NECROSIS-FACTOR-ALPHA AND MACROPHAGE INFLAMMATORY PROTEIN-1-ALPHA. JOURNAL OF CLINICAL INVESTIGATION, 91(6), 2673-2684.

DISTINCT PATTERNS OF EARLY RESPONSE GENE-EXPRESSION AND PROLIFERATION IN MOUSE MAST-CELLS STIMULATED BY STEM-CELL FACTOR, INTERLEUKIN-3, OR IGE AND ANTIGEN
Tsai, M., Tam, S. Y., & GALLI, S. J. (1993). DISTINCT PATTERNS OF EARLY RESPONSE GENE-EXPRESSION AND PROLIFERATION IN MOUSE MAST-CELLS STIMULATED BY STEM-CELL FACTOR, INTERLEUKIN-3, OR IGE AND ANTIGEN. EUROPEAN JOURNAL OF IMMUNOLOGY, 23(4), 867-872.

CLONING AND FUNCTIONAL-ANALYSIS OF THE MOUSE C-KIT PROMOTER
Yasuda, H., GALLI, S. J., & Geissler, E. N. (1993). CLONING AND FUNCTIONAL-ANALYSIS OF THE MOUSE C-KIT PROMOTER. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 191(3), 893-901.

MAST-CELL ACTIVATION ENHANCES AIRWAY RESPONSIVENESS TO METHACHOLINE IN THE MOUSE
Martin, T. R., Takeishi, T., Katz, H. R., Austen, K. F., Drazen, J. M., & GALLI, S. J. (1993). MAST-CELL ACTIVATION ENHANCES AIRWAY RESPONSIVENESS TO METHACHOLINE IN THE MOUSE. JOURNAL OF CLINICAL INVESTIGATION, 91(3), 1176-1182.

New concepts about the mast cell.
GALLI, S. J. (1993). New concepts about the mast cell. New England journal of medicine, 328(4), 257-265.

REVERSIBLE EXPANSION OF PRIMATE MAST-CELL POPULATIONS INVIVO BY STEM-CELL FACTOR
GALLI, S. J., Iemura, A., Garlick, D. S., GAMBAVITALO, C., Zsebo, K. M., & Andrews, R. G. (1993). REVERSIBLE EXPANSION OF PRIMATE MAST-CELL POPULATIONS INVIVO BY STEM-CELL FACTOR. JOURNAL OF CLINICAL INVESTIGATION, 91(1), 148-152.

THE HUMAN RECOMBINANT C-KIT RECEPTOR LIGAND, RHSCF, INDUCES MEDIATOR RELEASE FROM HUMAN CUTANEOUS MAST-CELLS AND ENHANCES IGE-DEPENDENT MEDIATOR RELEASE FROM BOTH SKIN MAST-CELLS AND PERIPHERAL-BLOOD BASOPHILS
Columbo, M., Horowitz, E. M., Botana, L. M., MacGlashan, D. W., Bochner, B. S., & LICHTENSTEIN, L. M. (1992). THE HUMAN RECOMBINANT C-KIT RECEPTOR LIGAND, RHSCF, INDUCES MEDIATOR RELEASE FROM HUMAN CUTANEOUS MAST-CELLS AND ENHANCES IGE-DEPENDENT MEDIATOR RELEASE FROM BOTH SKIN MAST-CELLS AND PERIPHERAL-BLOOD BASOPHILS. JOURNAL OF IMMUNOLOGY, 149(2), 599-608.

THE RAT C-KIT LIGAND, STEM-CELL FACTOR, INDUCES C-KIT RECEPTOR-DEPENDENT MOUSE MAST-CELL ACTIVATION INVIVO - EVIDENCE THAT SIGNALING THROUGH THE C-KIT RECEPTOR CAN INDUCE EXPRESSION OF CELLULAR FUNCTION
Wershil, B. K., Tsai, M., Geissler, E. N., Zsebo, K. M., & GALLI, S. J. (1992). THE RAT C-KIT LIGAND, STEM-CELL FACTOR, INDUCES C-KIT RECEPTOR-DEPENDENT MOUSE MAST-CELL ACTIVATION INVIVO - EVIDENCE THAT SIGNALING THROUGH THE C-KIT RECEPTOR CAN INDUCE EXPRESSION OF CELLULAR FUNCTION. JOURNAL OF EXPERIMENTAL MEDICINE, 175(1), 245-255.

CYTOKINE PRODUCTION BY MAST-CELLS AND BASOPHILS
GALLI, S. J., Gordon, J. R., & Wershil, B. K. (1991). CYTOKINE PRODUCTION BY MAST-CELLS AND BASOPHILS. CURRENT OPINION IN IMMUNOLOGY, 3(6), 865-873.

DIFFERENCES IN THE EXPRESSION OF THE CARDIOPULMONARY ALTERATIONS ASSOCIATED WITH ANTI-IMMUNOGLOBULIN-E-INDUCED OR ACTIVE ANAPHYLAXIS IN MAST-CELL DEFICIENT AND NORMAL MICE - MAST-CELLS ARE NOT REQUIRED FOR THE CARDIOPULMONARY CHANGES ASSOCIATED WITH CERTAIN FATAL ANAPHYLACTIC RESPONSES
Takeishi, T., Martin, T. R., Katona, I. M., Finkelman, F. D., & GALLI, S. J. (1991). DIFFERENCES IN THE EXPRESSION OF THE CARDIOPULMONARY ALTERATIONS ASSOCIATED WITH ANTI-IMMUNOGLOBULIN-E-INDUCED OR ACTIVE ANAPHYLAXIS IN MAST-CELL DEFICIENT AND NORMAL MICE - MAST-CELLS ARE NOT REQUIRED FOR THE CARDIOPULMONARY CHANGES ASSOCIATED WITH CERTAIN FATAL ANAPHYLACTIC RESPONSES. JOURNAL OF CLINICAL INVESTIGATION, 88(2), 598-608.

RELEASE OF BOTH PREFORMED AND NEWLY SYNTHESIZED TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA)/CACHECTIN BY MOUSE MAST-CELLS STIMULATED VIA THE FC-EPSILON-RI - A MECHANISM FOR THE SUSTAINED ACTION OF MAST-CELL DERIVED TNF-ALPHA DURING IGE-DEPENDENT BIOLOGICAL RESPONSES
Gordon, J. R., & GALLI, S. J. (1991). RELEASE OF BOTH PREFORMED AND NEWLY SYNTHESIZED TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA)/CACHECTIN BY MOUSE MAST-CELLS STIMULATED VIA THE FC-EPSILON-RI - A MECHANISM FOR THE SUSTAINED ACTION OF MAST-CELL DERIVED TNF-ALPHA DURING IGE-DEPENDENT BIOLOGICAL RESPONSES. JOURNAL OF EXPERIMENTAL MEDICINE, 174(1), 103-107.

INDUCTION OF MAST-CELL PROLIFERATION, MATURATION, AND HEPARIN SYNTHESIS BY THE RAT C-KIT LIGAND, STEM-CELL FACTOR
Tsai, M., Takeishi, T., Thompson, H., Langley, K. E., Zsebo, K. M., & GALLI, S. J. (1991). INDUCTION OF MAST-CELL PROLIFERATION, MATURATION, AND HEPARIN SYNTHESIS BY THE RAT C-KIT LIGAND, STEM-CELL FACTOR. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 88(14), 6382-6386.

THE RAT C-KIT LIGAND, STEM-CELL FACTOR, INDUCES THE DEVELOPMENT OF CONNECTIVE-TISSUE TYPE AND MUCOSAL MAST-CELLS INVIVO - ANALYSIS BY ANATOMICAL DISTRIBUTION, HISTOCHEMISTRY, AND PROTEASE PHENOTYPE
Tsai, M., Shih, L. S., Newlands, G. Fj., Takeishi, T., Langley, K. E., & GALLI, S. J. (1991). THE RAT C-KIT LIGAND, STEM-CELL FACTOR, INDUCES THE DEVELOPMENT OF CONNECTIVE-TISSUE TYPE AND MUCOSAL MAST-CELLS INVIVO - ANALYSIS BY ANATOMICAL DISTRIBUTION, HISTOCHEMISTRY, AND PROTEASE PHENOTYPE. JOURNAL OF EXPERIMENTAL MEDICINE, 174(1), 125-131.

MOUSE SPLENIC AND BONE-MARROW CELL-POPULATIONS THAT EXPRESS HIGH-AFFINITY FC-EPSILON RECEPTORS AND PRODUCE INTERLEUKIN-4 ARE HIGHLY ENRICHED IN BASOPHILS
SEDER, R. A., PAUL, W. E., Dvorak, A. M., Sharkis, S. J., KAGEYSOBOTKA, A., & Plaut, M. (1991). MOUSE SPLENIC AND BONE-MARROW CELL-POPULATIONS THAT EXPRESS HIGH-AFFINITY FC-EPSILON RECEPTORS AND PRODUCE INTERLEUKIN-4 ARE HIGHLY ENRICHED IN BASOPHILS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 88(7), 2835-2839.

STEM-CELL FACTOR (SCF), A NOVEL HEMATOPOIETIC GROWTH-FACTOR AND LIGAND FOR C-KIT TYROSINE KINASE RECEPTOR, MAPS ON HUMAN-CHROMOSOME 12 BETWEEN 12Q14.3 AND 12QTER
Geissler, E. N., Liao, M., BROOK, J. D., Martin, F. H., Zsebo, K. M., & GALLI, S. J. (1991). STEM-CELL FACTOR (SCF), A NOVEL HEMATOPOIETIC GROWTH-FACTOR AND LIGAND FOR C-KIT TYROSINE KINASE RECEPTOR, MAPS ON HUMAN-CHROMOSOME 12 BETWEEN 12Q14.3 AND 12QTER. SOMATIC CELL AND MOLECULAR GENETICS, 17(2), 207-214.

RECRUITMENT OF NEUTROPHILS DURING IGE-DEPENDENT CUTANEOUS LATE PHASE REACTIONS IN THE MOUSE IS MAST CELL-DEPENDENT - PARTIAL INHIBITION OF THE REACTION WITH ANTISERUM AGAINST TUMOR-NECROSIS-FACTOR-ALPHA
Wershil, B. K., Wang, Z. S., Gordon, J. R., & GALLI, S. J. (1991). RECRUITMENT OF NEUTROPHILS DURING IGE-DEPENDENT CUTANEOUS LATE PHASE REACTIONS IN THE MOUSE IS MAST CELL-DEPENDENT - PARTIAL INHIBITION OF THE REACTION WITH ANTISERUM AGAINST TUMOR-NECROSIS-FACTOR-ALPHA. JOURNAL OF CLINICAL INVESTIGATION, 87(2), 446-453.

ROLE OF MAST-CELLS IN ION-TRANSPORT ABNORMALITIES ASSOCIATED WITH INTESTINAL ANAPHYLAXIS - CORRECTION OF THE DIMINISHED SECRETORY RESPONSE IN GENETICALLY MAST CELL-DEFICIENT W/WV MICE BY BONE-MARROW TRANSPLANTATION
Perdue, M. H., Masson, S., Wershil, B. K., & GALLI, S. J. (1991). ROLE OF MAST-CELLS IN ION-TRANSPORT ABNORMALITIES ASSOCIATED WITH INTESTINAL ANAPHYLAXIS - CORRECTION OF THE DIMINISHED SECRETORY RESPONSE IN GENETICALLY MAST CELL-DEFICIENT W/WV MICE BY BONE-MARROW TRANSPLANTATION. JOURNAL OF CLINICAL INVESTIGATION, 87(2), 687-693.

[I-125] FIBRIN DEPOSITION OCCURS AT BOTH EARLY AND LATE INTERVALS OF IGE-DEPENDENT OR CONTACT SENSITIVITY REACTIONS ELICITED IN MOUSE SKIN - MAST CELL-DEPENDENT AUGMENTATION OF FIBRIN DEPOSITION AT EARLY INTERVALS IN COMBINED IGE-DEPENDENT AND CONTACT SENSITIVITY REACTIONS
Mekori, Y. A., & GALLI, S. J. (1990). [I-125] FIBRIN DEPOSITION OCCURS AT BOTH EARLY AND LATE INTERVALS OF IGE-DEPENDENT OR CONTACT SENSITIVITY REACTIONS ELICITED IN MOUSE SKIN - MAST CELL-DEPENDENT AUGMENTATION OF FIBRIN DEPOSITION AT EARLY INTERVALS IN COMBINED IGE-DEPENDENT AND CONTACT SENSITIVITY REACTIONS. JOURNAL OF IMMUNOLOGY, 145(11), 3719-3727.

MAST-CELLS AS A SOURCE OF MULTIFUNCTIONAL CYTOKINES
Gordon, J. R., Burd, P. R., & GALLI, S. J. (1990). MAST-CELLS AS A SOURCE OF MULTIFUNCTIONAL CYTOKINES. IMMUNOLOGY TODAY, 11(12), 458-464.

HUMAN EOSINOPHILS EXPRESS TRANSFORMING GROWTH FACTOR-ALPHA
Wong, D. Tw., Weller, P. F., GALLI, S. J., Elovic, A., RAND, T. H., & Todd, R. (1990). HUMAN EOSINOPHILS EXPRESS TRANSFORMING GROWTH FACTOR-ALPHA. JOURNAL OF EXPERIMENTAL MEDICINE, 172(3), 673-681.

MAST-CELLS AS A SOURCE OF BOTH PREFORMED AND IMMUNOLOGICALLY INDUCIBLE TNF-ALPHA CACHECTIN
Gordon, J. R., & GALLI, S. J. (1990). MAST-CELLS AS A SOURCE OF BOTH PREFORMED AND IMMUNOLOGICALLY INDUCIBLE TNF-ALPHA CACHECTIN. NATURE, 346(6281), 274-276.

ANATOMICAL VARIATION IN MAST-CELL NERVE ASSOCIATIONS IN THE RAT SMALL-INTESTINE, HEART, LUNG, AND SKIN - SIMILARITIES OF DISTANCES BETWEEN NEURAL PROCESSES AND MAST-CELLS, EOSINOPHILS, OR PLASMA-CELLS IN THE JEJUNAL LAMINA PROPRIA
Arizono, N., Matsuda, S., Hattori, T., Kojima, Y., Maeda, T., & GALLI, S. J. (1990). ANATOMICAL VARIATION IN MAST-CELL NERVE ASSOCIATIONS IN THE RAT SMALL-INTESTINE, HEART, LUNG, AND SKIN - SIMILARITIES OF DISTANCES BETWEEN NEURAL PROCESSES AND MAST-CELLS, EOSINOPHILS, OR PLASMA-CELLS IN THE JEJUNAL LAMINA PROPRIA. LABORATORY INVESTIGATION, 62(5), 626-634.

PHORBOL 12-MYRISTATE 13-ACETATE INDUCED DEVELOPMENT OF FUNCTIONALLY ACTIVE MAST-CELLS IN W/WV BUT NOT SL/SLD GENETICALLY MAST CELL-DEFICIENT MICE
Gordon, J. R., & GALLI, S. J. (1990). PHORBOL 12-MYRISTATE 13-ACETATE INDUCED DEVELOPMENT OF FUNCTIONALLY ACTIVE MAST-CELLS IN W/WV BUT NOT SL/SLD GENETICALLY MAST CELL-DEFICIENT MICE. BLOOD, 75(8), 1637-1645.

New insights into "the riddle of the mast cells": microenvironmental regulation of mast cell development and phenotypic heterogeneity.
GALLI, S. J. (1990). New insights into "the riddle of the mast cells": microenvironmental regulation of mast cell development and phenotypic heterogeneity. Laboratory investigation; a journal of technical methods and pathology, 62(1), 5-33.

SUBSTANCE-P-INDUCED AUGMENTATION OF CUTANEOUS VASCULAR-PERMEABILITY AND GRANULOCYTE INFILTRATION IN MICE IS MAST-CELL DEPENDENT
Yano, H., Wershil, B. K., Arizono, N., & GALLI, S. J. (1989). SUBSTANCE-P-INDUCED AUGMENTATION OF CUTANEOUS VASCULAR-PERMEABILITY AND GRANULOCYTE INFILTRATION IN MICE IS MAST-CELL DEPENDENT. JOURNAL OF CLINICAL INVESTIGATION, 84(4), 1276-1286.

ANALYSIS OF MAST-CELL FUNCTION IN BIOLOGICAL RESPONSES NOT INVOLVING IGE
GALLI, S. J., Wershil, B. K., & Mekori, Y. A. (1987). ANALYSIS OF MAST-CELL FUNCTION IN BIOLOGICAL RESPONSES NOT INVOLVING IGE. INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, 82(3-4), 269-271.