Biography
Professional Summary
Education & Certifications
- Medical Education: Stanford University School of Medicine (1976) CA
- Fellowship: National Institutes of Health - Office of Education (1980) MD
- Residency: Massachusetts General Hospital Internal Medicine Residency (1978) MA
- Internship: Massachusetts General Hospital Internal Medicine Residency (1977) MA
- Board Certification: American Board of Internal Medicine, Endocrinology, Diabetes and Metabolism (1981)
- Fellowship: Massachusetts General Hospital (1982) MA
- Board Certification: American Board of Internal Medicine, Internal Medicine (1979)
- BA, University of Michigan, History (1971)
- MD, Stanford, Medicine (1976)
Administrative Appointments
- Member, Stanford Diabetes Research Center (2017 - Present)
- Senior Vice Chair for Academic Affairs, Department of Medicine, Stanford (2004 - Present)
Publications
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One year of insulin-like growth factor I treatment does not affect bone density, body composition, or psychological measures in postmenopausal women
Friedlander, A. L., Butterfield, E., Moynihan, S., Grillo, J., Pollack, M., Holloway, L., … Hoffman, A. R. (2001). One year of insulin-like growth factor I treatment does not affect bone density, body composition, or psychological measures in postmenopausal women. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 86(4), 1496–1503. -
An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa
Li, T., Vu, T. H., Lee, K. O., Yang, Y. W., Nguyen, C. V., Bui, H. Q., … Hoffman, A. R. (2002). An imprinted PEG1/MEST antisense expressed predominantly in human testis and in mature spermatozoa. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(16), 13518–27. -
A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma
Yao, X. M., Hu, J. F., Daniels, M., Shiran, H., Zhou, X. J., Yan, H. F., … Hoffman, A. R. (2003). A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma. JOURNAL OF CLINICAL INVESTIGATION, 111(2), 265–273. -
Activating and silencing histone modifications form independent allelic switch regions in the imprinted Gnas gene
Li, T., Vu, T. H., Yang, Y. W., Hu, J. F., & Hoffman, A. R. (2004). Activating and silencing histone modifications form independent allelic switch regions in the imprinted Gnas gene. HUMAN MOLECULAR GENETICS, 13(7), 741–50. -
Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse
Vu, T. H., Li, T., & Hoffman, A. R. (2004). Promoter-restricted histone code, not the differentially methylated DNA regions or antisense transcripts, marks the imprinting status of IGF2R in human and mouse. HUMAN MOLECULAR GENETICS, 13(19), 2233–45. -
Efficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency
Hoffman, A. R., Biller, B. M. K., Cook, D., Baptista, J., Silverman, B. L., Dao, L., … Lippe, B. (2005). Efficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 90(12), 6431–6440. -
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1
Ling, J. Q., Li, T., Hu, J. F., Vu, T. H., Chen, H. L., Qiu, X. W., … Hoffman, A. R. (2006). CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1. SCIENCE, 312(5771), 269–72. -
Systematic review: The safety and efficacy of growth hormone in the healthy elderly
Liu, H., Bravata, D. M., Olkin, I., Nayak, S., Roberts, B., Garber, A. M., & Hoffman, A. R. (2007). Systematic review: The safety and efficacy of growth hormone in the healthy elderly. ANNALS OF INTERNAL MEDICINE, 146(2), 104–15. -
Generation of novel adipocyte monolayer cultures from embryonic stem cells
Chen, T. L., Shen, W.-J., Qiu, X.-W., Li, T., Hoffman, A. R., & Kraemer, F. B. (2007). Generation of novel adipocyte monolayer cultures from embryonic stem cells. STEM CELLS AND DEVELOPMENT, 16(3), 371–380. -
Systematic review: The effects of growth hormone on athletic performance
Liu, H., Bravata, D. M., Olkin, I., Friedlander, A., Liu, V., Roberts, B., … Hoffman, A. R. (2008). Systematic review: The effects of growth hormone on athletic performance. ANNALS OF INTERNAL MEDICINE, 148(10), 747–U59. -
A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele
Qiu, X., Vu, T. H., Lu, Q., Ling, J. Q., Li, T., Hou, A., … Hoffman, A. R. (2008). A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele. MOLECULAR ENDOCRINOLOGY, 22(6), 1476–1488. -
CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop
Li, T., Hu, J.-F., Qiu, X., Ling, J., Chen, H., Wang, S., … Hoffman, A. R. (2008). CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop. MOLECULAR AND CELLULAR BIOLOGY, 28(20), 6473–6482. -
Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3 '-UTR microRNA
Zhang, J., Huang, S., Zhang, H., Wang, H., Guo, H., Qian, G., … Ge, S. (2010). Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3 '-UTR microRNA. INTERNATIONAL JOURNAL OF CANCER, 126(9), 2229–39. -
Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells
Vu, T. H., Nguyen, A. H., & Hoffman, A. R. (2010). Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells. HUMAN MOLECULAR GENETICS, 19(5), 901–19. -
Putative Tumor Suppressor miR-145 Inhibits Colon Cancer Cell Growth by Targeting Oncogene Friend Leukemia Virus Integration 1 Gene
Zhang, J., Guo, H., Zhang, H., Wang, H., Qian, G., Fan, X., … Ge, S. (2011). Putative Tumor Suppressor miR-145 Inhibits Colon Cancer Cell Growth by Targeting Oncogene Friend Leukemia Virus Integration 1 Gene. CANCER, 117(1), 86–95. -
Mortality Risk in Older Men Associated with Changes in Weight, Lean Mass, and Fat Mass
Lee, C. G., Boyko, E. J., Nielson, C. M., Stefanick, M. L., Bauer, D. C., Hoffman, A. R., … Orwoll, E. S. (2011). Mortality Risk in Older Men Associated with Changes in Weight, Lean Mass, and Fat Mass. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 59(2), 233–40. -
Interruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic imprinting of human insulin-like growth factor II
Zhang, H., Niu, B., Hu, J.-F., Ge, S. F., Wang, H., Li, T., … Hoffman, A. R. (2011). Interruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic imprinting of human insulin-like growth factor II. JOURNAL OF CELL BIOLOGY, 193(3), 475–487. -
IGFBP-2 Enhances VEGF Gene Promoter Activity and Consequent Promotion of Angiogenesis by Neuroblastoma Cells
Azar, W. J., Azar, S. H. X., Higgins, S., Hu, J.-F., Hoffman, A. R., Newgreen, D. F., … Russo, V. C. (2011). IGFBP-2 Enhances VEGF Gene Promoter Activity and Consequent Promotion of Angiogenesis by Neuroblastoma Cells. ENDOCRINOLOGY, 152(9), 3332–3342. -
Higher Testosterone Levels Are Associated with Less Loss of Lean Body Mass in Older Men
LeBlanc, E. S., Wang, P. Y., Lee, C. G., Barrett-Connor, E., Cauley, J. A., Hoffman, A. R., … Orwoll, E. S. (2011). Higher Testosterone Levels Are Associated with Less Loss of Lean Body Mass in Older Men. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 96(12), 3855–63. -
Long-Term Surveillance of Growth Hormone Therapy
Rosenfeld, R. G., Cohen, P., Robison, L. L., Bercu, B. B., Clayton, P., Hoffman, A. R., … Wit, J. M. (2012). Long-Term Surveillance of Growth Hormone Therapy. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 97(1), 68–72. -
Thyroid Function and Mortality in Older Men: A Prospective Study
Waring, A. C., Harrison, S., Samuels, M. H., Ensrud, K. E., LeBlanc, E. S., Hoffman, A. R., … Bauer, D. C. (2012). Thyroid Function and Mortality in Older Men: A Prospective Study. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 97(3), 862–870. -
Successful long-term treatment of Cushing disease with mifepristone (RU486).
Basina, M., Liu, H., Hoffman, A. R., & Feldman, D. (2012). Successful long-term treatment of Cushing disease with mifepristone (RU486). Endocrine Practice , 18(5), e114–20. -
Promotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone triiodothyronine-activated PI3K/AKT signal pathway
Chen, M., Zhang, H., Wu, J., Xu, L., Xu, D., Sun, J., … Li, T. (2012). Promotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone triiodothyronine-activated PI3K/AKT signal pathway. BIOMATERIALS, 33(22), 5514–23. -
The Association of Concurrent Vitamin D and Sex Hormone Deficiency With Bone Loss and Fracture Risk in Older Men: The Osteoporotic Fractures in Men (MrOS) Study
Barrett-Connor, E., Laughlin, G. A., Li, H., Nielson, C. M., Wang, P. Y., Dam, T. T., … Orwoll, E. S. (2012). The Association of Concurrent Vitamin D and Sex Hormone Deficiency With Bone Loss and Fracture Risk in Older Men: The Osteoporotic Fractures in Men (MrOS) Study. JOURNAL OF BONE AND MINERAL RESEARCH, 27(11), 2306–2313. -
Abdominal Myosteatosis Is Independently Associated with Hyperinsulinemia and Insulin Resistance Among Older Men Without Diabetes
Miljkovic, I., Cauley, J. A., Wang, P. Y., Holton, K. F., Lee, C. G., Sheu, Y., … Marshall, L. M. (2013). Abdominal Myosteatosis Is Independently Associated with Hyperinsulinemia and Insulin Resistance Among Older Men Without Diabetes. OBESITY, 21(10), 2118–25. -
Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming
Zhang, H., Jiao, W., Sun, L., Fan, J., Chen, M., Wang, H., … Hu, J.-F. (2013). Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming. CELL STEM CELL, 13(1), 30–35. -
MILK-ALKALI SYNDROME IN PATIENTS TREATED WITH CALCIUM-CARBONATE AFTER CARDIAC TRANSPLANTATION
Kapsner, P., LANGSDORF, L., Marcus, R., Kraemer, F. B., & Hoffman, A. R. (1986). MILK-ALKALI SYNDROME IN PATIENTS TREATED WITH CALCIUM-CARBONATE AFTER CARDIAC TRANSPLANTATION. ARCHIVES OF INTERNAL MEDICINE, 146(10), 1965–1968. -
ACROMEGALY AND ZOLLINGER-ELLISON SYNDROME SECONDARY TO AN ISLET CELL TUMOR - CHARACTERIZATION AND QUANTIFICATION OF PLASMA AND TUMOR HUMAN GROWTH HORMONE-RELEASING FACTOR
Wilson, D. M., Ceda, G. P., Bostwick, D. G., Webber, R. J., Minkoff, J. R., Pont, A., … Hoffman, A. R. (1984). ACROMEGALY AND ZOLLINGER-ELLISON SYNDROME SECONDARY TO AN ISLET CELL TUMOR - CHARACTERIZATION AND QUANTIFICATION OF PLASMA AND TUMOR HUMAN GROWTH HORMONE-RELEASING FACTOR. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 59(5), 1002–5. -
CHARACTERIZATION OF HIGH-AFFINITY RECEPTORS FOR INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II ON RAT ANTERIOR-PITUITARY CELLS
Rosenfeld, R. G., Ceda, G., Wilson, D. M., DOLLAR, L. A., & Hoffman, A. R. (1984). CHARACTERIZATION OF HIGH-AFFINITY RECEPTORS FOR INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II ON RAT ANTERIOR-PITUITARY CELLS. ENDOCRINOLOGY, 114(5), 1571–75. -
PROMOTER-SPECIFIC IMPRINTING OF THE HUMAN INSULIN-LIKE GROWTH FACTOR-II GENE
Vu, T. H., & Hoffman, A. R. (1994). PROMOTER-SPECIFIC IMPRINTING OF THE HUMAN INSULIN-LIKE GROWTH FACTOR-II GENE. NATURE, 371(6499), 714–717. -
Imprinting of the Angelman syndrome gene, UBE3A, is restricted to brain
Vu, T. H., & Hoffman, A. R. (1997). Imprinting of the Angelman syndrome gene, UBE3A, is restricted to brain. NATURE GENETICS, 17(1), 12–13. -
SUPPRESSION OF TUMOR SECRETION OF GROWTH-HORMONE RELEASING-FACTOR (GRF 1-40) AND GASTRIN BY A SOMATOSTATIN ANALOG
Wilson, D. M., & Hoffman, A. R. (1985). SUPPRESSION OF TUMOR SECRETION OF GROWTH-HORMONE RELEASING-FACTOR (GRF 1-40) AND GASTRIN BY A SOMATOSTATIN ANALOG. CLINICAL RESEARCH, 33(1), A31–A31. -
REGULATION OF GROWTH-HORMONE RELEASE FROM CULTURED HUMAN PITUITARY-ADENOMAS BY SOMATOMEDINS AND INSULIN
Ceda, G. P., Hoffman, A. R., Silverberg, G. D., Wilson, D. M., & Rosenfeld, R. G. (1985). REGULATION OF GROWTH-HORMONE RELEASE FROM CULTURED HUMAN PITUITARY-ADENOMAS BY SOMATOMEDINS AND INSULIN. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 60(6), 1204–9. -
ACROMEGALY AND PHEOCHROMOCYTOMA - A MULTIPLE ENDOCRINE SYNDROME CAUSED BY A PLURIHORMONAL ADRENAL-MEDULLARY TUMOR
Roth, K. A., Wilson, D. M., Eberwine, J., Dorin, R. I., Kovacs, K., Bensch, K. G., & Hoffman, A. R. (1986). ACROMEGALY AND PHEOCHROMOCYTOMA - A MULTIPLE ENDOCRINE SYNDROME CAUSED BY A PLURIHORMONAL ADRENAL-MEDULLARY TUMOR. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 63(6), 1421–26. -
Time-dependent effects of intermittent hydrostatic pressure on articular chondrocyte type II collagen and aggrecan mRNA expression
Smith, R. L., Lin, J., Trindade, M. C. D., Shida, J., KAJIYAMA, G., Vu, T., … Carter, D. R. (2000). Time-dependent effects of intermittent hydrostatic pressure on articular chondrocyte type II collagen and aggrecan mRNA expression. JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT, 37(2), 153–61. -
Mortality Risks with Body Composition Change in Older Men.
Lee, C. G., Boyko, E. J., Nielson, C. M., Bauer, D. C., Hoffman, A. R., Cawthon, P. M., … Orwoll, E. S. (2010). Mortality Risks with Body Composition Change in Older Men. Presented at the Annual Meeting of the American-Geriatrics-Society, ORLANDO,FL,FL,FL,FL: WILEY-BLACKWELL. -
INCREASED RISK OF LEAN MASS LOSS ASSOCIATED WITH INSULIN RESISTANCE IN OLDER MEN
Lee, C. G., Boyko, E. J., Strotmeyer, E. S., Cawthon, P. M., Hoffman, A. R., Everson-Rose, S., … Orwoll, E. (2010). INCREASED RISK OF LEAN MASS LOSS ASSOCIATED WITH INSULIN RESISTANCE IN OLDER MEN. OXFORD UNIV PRESS INC. -
COMBINED CHANGES IN MUSCLE AND FAT ASSOCIATED WITH LOSS IN POWER
Lee, C. G., Marshall, L. M., LeBlanc, E. S., Hoffman, A. R., Cauley, J. A., Strotmeyer, E. S., … Orwoll, E. (2011). COMBINED CHANGES IN MUSCLE AND FAT ASSOCIATED WITH LOSS IN POWER. OXFORD UNIV PRESS INC. -
Insulin Sensitizers May Attenuate Lean Mass Loss in Older Men With Diabetes
Lee, C. G., Boyko, E. J., Barrett-Connor, E., Miljkovic, I., Hoffman, A. R., Everson-Rose, S. A., … Orwoll, E. S. (2011). Insulin Sensitizers May Attenuate Lean Mass Loss in Older Men With Diabetes. DIABETES CARE, 34(11), 2381–86. -
Targeted tumor gene therapy based on loss of IGF2 imprinting
Pan, Y., He, B., Li, T., Zhu, C., Zhang, L., Wang, B., … Hu, J. (2010). Targeted tumor gene therapy based on loss of IGF2 imprinting. CANCER BIOLOGY & THERAPY, 10(3). -
Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system
Nie, Z.-L., Pan, Y.-Q., He, B.-S., Gu, L., Chen, L.-P., Li, R., … Hu, F. (2012). Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system. MOLECULAR CANCER, 11. -
Expression and heterozygosity of imprinting IGF-II and H19 in the human chondrosarcoma-derived cells. HCS-2/8 and -2/A
Takahashi, K., Vu, T. H., Hattori, T., Nakanishi, T., Hoffman, A. R., & Takigawa, M. (1997). Expression and heterozygosity of imprinting IGF-II and H19 in the human chondrosarcoma-derived cells. HCS-2/8 and -2/A. FASEB JOURNAL, 11(9), A937–A937. -
Optimized clinical performance of growth hormone with an expanded genetic code
Cho, H., Daniel, T., Buechler, Y. J., Litzinger, D. C., Maio, Z., Putnam, A.-M. H., … Kimmel, B. E. (2011). Optimized clinical performance of growth hormone with an expanded genetic code. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(22), 9060–65. -
THYROID-HORMONE UPREGULATES INSULIN-LIKE GROWTH FACTOR-I RECEPTORS IN CULTURED RAT PITUITARY-CELLS
GEARY, E. S., Lim, M. L., Ceda, G. P., Rosenfeld, R. G., & Hoffman, A. R. (1988). THYROID-HORMONE UPREGULATES INSULIN-LIKE GROWTH FACTOR-I RECEPTORS IN CULTURED RAT PITUITARY-CELLS. CLINICAL RESEARCH, 36(1), A152–A152. -
Effect of GMCSF on development and gene imprinting in preimplantation mouse embryos.
Littman, E. D., Ling, J. Q., Ulaner, G. A., Vu, T. H., Dasig, D., Lyon, J., … Behr, B. (2005). Effect of GMCSF on development and gene imprinting in preimplantation mouse embryos. Presented at the 53rd Annual Meeting of the Pacific-Coast-Reproductive-Society, INDIAN WELLS,CA: ELSEVIER SCIENCE INC. -
Igf2 gene imprinting in preimplantation mouse embryos
Littman, E. D., Ulaner, G. A., Vu, T. H., Otero, J., Dasig, D., Lyon, J., … Hoffman, A. R. (2004). Igf2 gene imprinting in preimplantation mouse embryos. Presented at the 52nd Annual Meeting of the Pacific-Coast-Reproductive-Society, RANCHO MIRAGE,CA: ELSEVIER SCIENCE INC. -
Epigenetics and long-range interactions.
Hoffman, A. R., & Ling, J. Q. (2006). Epigenetics and long-range interactions. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 47(6), 405–405. -
Correction of aberrant imprinting of IGF2 in human tumors by nuclear transfer-induced epigenetic reprogramming
Chen, H. L., Li, T., Qiu, X. W., Wu, J., Ling, J. Q., Sun, Z. H., … Hu, J.-F. (2006). Correction of aberrant imprinting of IGF2 in human tumors by nuclear transfer-induced epigenetic reprogramming. EMBO JOURNAL, 25(22), 5329–38. -
IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch
Li, T., Vu, T. H., Ulaner, G. A., Littman, E., Ling, J. Q., Chen, H. L., … Hoffman, A. R. (2005). IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch. MOLECULAR HUMAN REPRODUCTION, 11(9), 631–40. -
Transient in vitro epigenetic reprogramming of skin fibroblasts into multipotent cells
Zhu, X.-Q., Pan, X.-H., Wang, W., Chen, Q., Pang, R.-Q., Cai, X.-M., … Hu, J.-F. (2010). Transient in vitro epigenetic reprogramming of skin fibroblasts into multipotent cells. BIOMATERIALS, 31(10), 2779–87. -
Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restriction
Barnholt, K. E., Hoffman, A. R., Rock, P. B., Muza, S. R., Fulco, C. S., Braun, B., … Friedlander, A. L. (2006). Endocrine responses to acute and chronic high-altitude exposure (4,300 meters): modulating effects of caloric restriction. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 290(6), E1078–E1088. -
INSULIN-LIKE GROWTH-FACTORS (IGFS), IGF BINDING-PROTEINS (IGFBPS) AND IGFBP PROTEASE IN HUMAN UTERINE ENDOMETRIUM - THEIR POTENTIAL RELEVANCE TO ENDOMETRIAL CYCLIC FUNCTION AND MATERNAL-EMBRYONIC INTERACTIONS
Giudice, L. C., Irwin, J. C., DSUPIN, B. A., DELASFUENTES, L., JIN, I. H., Vu, T. H., & Hoffman, A. R. (1994). INSULIN-LIKE GROWTH-FACTORS (IGFS), IGF BINDING-PROTEINS (IGFBPS) AND IGFBP PROTEASE IN HUMAN UTERINE ENDOMETRIUM - THEIR POTENTIAL RELEVANCE TO ENDOMETRIAL CYCLIC FUNCTION AND MATERNAL-EMBRYONIC INTERACTIONS. Presented at the 3rd International Symposium on Insulin-Like Growth Factors, SYDNEY,AUSTRALIA: ELSEVIER SCIENCE PUBL B V. -
Effects of growth hormone and pioglitazone in viscerally obese adults with impaired glucose tolerance: A factorial clinical trial
Attallah, H., Friedlander, A. L., Nino-Murcia, M., & Hoffman, A. R. (2007). Effects of growth hormone and pioglitazone in viscerally obese adults with impaired glucose tolerance: A factorial clinical trial. PLOS CLINICAL TRIALS, 2(5). -
Nocturnal Arrhythmias Across a Spectrum of Obstructive and Central Sleep-Disordered Breathing in Older Men Outcomes of Sleep Disorders in Older Men (MrOS Sleep) Study
Mehra, R., Stone, K. L., Varosy, P. D., Hoffman, A. R., Marcus, G. M., Blackwell, T., … Redline, S. (2009). Nocturnal Arrhythmias Across a Spectrum of Obstructive and Central Sleep-Disordered Breathing in Older Men Outcomes of Sleep Disorders in Older Men (MrOS Sleep) Study. ARCHIVES OF INTERNAL MEDICINE, 169(12), 1147–55. -
Bone Mass and Strength in Older Men With Type 2 Diabetes: The Osteoporotic Fractures in Men Study
Petit, M. A., Paudel, M. L., Taylor, B. C., Hughes, J. M., Strotmeyer, E. S., Schwartz, A. V., … Ensrud, K. E. (2010). Bone Mass and Strength in Older Men With Type 2 Diabetes: The Osteoporotic Fractures in Men Study. JOURNAL OF BONE AND MINERAL RESEARCH, 25(2), 285–291. -
DELAYED INCREASE OF ADRENAL TH AND PNMT ACTIVITIES FOLLOWING COLD STRESS IN MOUSE
Hoffman, A., Harbaugh, R., Erdelyi, E., DORNBUSCH, J., CIARANELLO, R., & BARCHAS, J. (1975). DELAYED INCREASE OF ADRENAL TH AND PNMT ACTIVITIES FOLLOWING COLD STRESS IN MOUSE. LIFE SCIENCES, 17(4), 557–562. -
Serum 25-OH vitamin D levels and risk of developing prostate cancer in older men
Barnett, C. M., Nielson, C. M., Shannon, J., Chan, J. M., Shikany, J. M., Bauer, D. C., … Beer, T. M. (2010). Serum 25-OH vitamin D levels and risk of developing prostate cancer in older men. CANCER CAUSES & CONTROL, 21(8), 1297–1303. -
Validation of FRC, a Fracture Risk Assessment Tool, in a Cohort of Older Men: The Osteoporotic Fractures in Men (MrOS) Study
Ettinger, B., Liu, H., Blackwell, T., Hoffman, A. R., Ensrud, K. E., & Orwoll, E. S. (2012). Validation of FRC, a Fracture Risk Assessment Tool, in a Cohort of Older Men: The Osteoporotic Fractures in Men (MrOS) Study. JOURNAL OF CLINICAL DENSITOMETRY, 15(3), 334–342. -
CHARACTERIZATION OF OPIOID-PEPTIDES IN HUMAN THYROID MEDULLARY CARCINOMA
Roth, K. A., Bensch, K. G., & Hoffman, A. R. (1987). CHARACTERIZATION OF OPIOID-PEPTIDES IN HUMAN THYROID MEDULLARY CARCINOMA. CANCER, 59(9), 1594–1598. -
Cyclic Hypobaric Hypoxia Improves Markers of Glucose Metabolism in Middle-Aged Men
Marquez, J. L., Rubinstein, S., Fattor, J. A., Shah, O., Hoffman, A. R., & Friedlander, A. L. (2013). Cyclic Hypobaric Hypoxia Improves Markers of Glucose Metabolism in Middle-Aged Men. HIGH ALTITUDE MEDICINE & BIOLOGY, 14(3), 263–72. -
Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture
Zeitz, M. J., Ay, F., Heidmann, J. D., Lerner, P. L., Noble, W. S., Steelman, B. N., & Hoffman, A. R. (2013). Genomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture. PLOS ONE, 8(9). -
Implications of COMT long-range interactions on the phenotypic variability of 22q11.2 deletion syndrome.
Zeitz, M. J., Lerner, P. P., Ay, F., Van Nostrand, E., Heidmann, J. D., Noble, W. S., & Hoffman, A. R. (2013). Implications of COMT long-range interactions on the phenotypic variability of 22q11.2 deletion syndrome. Nucleus (Austin, Tex.), 4(6), 487–93. -
Promoter histone H3K27 methylation in the control of IGF2 imprinting in human tumor cell lines
Li, T., Chen, H., Li, W., Cui, J., Wang, G., Hu, X., … Hu, J. (2014). Promoter histone H3K27 methylation in the control of IGF2 imprinting in human tumor cell lines. HUMAN MOLECULAR GENETICS, 23(1), 117–28. -
Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells
Zhang, S., Zhong, B., Chen, M., Yang, L., Yang, G., Li, Y., … Hu, J. (2014). Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells. INTERNATIONAL JOURNAL OF CANCER, 134(7), 1583–94. -
Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus
Zhang, H., Zeitz, M. J., Wang, H., Niu, B., Ge, S. F., Li, W., … Hu, J.-F. (2014). Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus. JOURNAL OF CELL BIOLOGY, 204(1), 61–75. -
DIFFERENTIAL-EFFECTS OF INSULIN-LIKE GROWTH-FACTOR (IGF)-I AND IGF-II ON THE EXPRESSION OF IGF BINDING-PROTEINS (IGFBPS) IN A RAT NEUROBLASTOMA CELL-LINE - ISOLATION AND CHARACTERIZATION OF 2 FORMS OF IGFBP-4
Ceda, G. P., Fielder, P. J., Henzel, W. J., Louie, A., Donovan, S. M., Hoffman, A. R., & Rosenfeld, R. G. (1991). DIFFERENTIAL-EFFECTS OF INSULIN-LIKE GROWTH-FACTOR (IGF)-I AND IGF-II ON THE EXPRESSION OF IGF BINDING-PROTEINS (IGFBPS) IN A RAT NEUROBLASTOMA CELL-LINE - ISOLATION AND CHARACTERIZATION OF 2 FORMS OF IGFBP-4. ENDOCRINOLOGY, 128(6), 2815–2824. -
Chromatin looping is needed for iPSC induction.
Hu, J.-F., & Hoffman, A. R. (2014). Chromatin looping is needed for iPSC induction. Cell Cycle , 13(1), 1–2. -
Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions.
Durruthy-Durruthy, J., Briggs, S. F., Awe, J., Ramathal, C. Y., Karumbayaram, S., Lee, P. C., … Sebastiano, V. (2014). Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions. PloS One, 9(4). -
Visceral obesity, impaired glucose tolerance, metabolic syndrome, and growth hormone therapy
Attallah, H., Friedlander, A. L., & Hoffman, A. R. (2006). Visceral obesity, impaired glucose tolerance, metabolic syndrome, and growth hormone therapy. Presented at the 19th Annual National Cooperative Growth Study/1st Annual National Cooperative Metabolic Study Investigator Meeting, SAN FRANCISCO,CA,CA: CHURCHILL LIVINGSTONE. -
Epigenetic regulation of the taxol resistance-associated gene TRAG-3 in human tumors
Yao, X. M., Hu, J. F., Li, T., Yang, Y. W., Sun, Z. H., Ulaner, G. A., … Hoffman, A. R. (2004). Epigenetic regulation of the taxol resistance-associated gene TRAG-3 in human tumors. CANCER GENETICS AND CYTOGENETICS, 151(1), 1–13. -
Lack of effect of recombinant human growth hormone (GH) on muscle morphology and GH-insulin-like growth factor expression in resistance-trained elderly men
Taaffe, D. R., JIN, I. H., Vu, T. H., Hoffman, A. R., & Marcus, R. (1996). Lack of effect of recombinant human growth hormone (GH) on muscle morphology and GH-insulin-like growth factor expression in resistance-trained elderly men. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 81(1), 421–425. -
Comparative genome analysis of the mouse imprinted gene IMPACT and its nonimprinted human homolog IMPACT: Toward the structural basis for species-specific imprinting
Okamura, K., Hagiwara-Takeuchi, Y., Li, T., Vu, T. H., Hirai, M., Hattori, M., … Ito, T. (2000). Comparative genome analysis of the mouse imprinted gene IMPACT and its nonimprinted human homolog IMPACT: Toward the structural basis for species-specific imprinting. GENOME RESEARCH, 10(12), 1878–1889. -
ASSOCIATION BETWEEN THYROID FUNCTION AND OBJECTIVE AND SUBJECTIVE SLEEP QUALITY IN OLDER MEN: THE OSTEOPOROTIC FRACTURES IN MEN (MROS) STUDY
Akatsu, H., Ewing, S. K., Stefanick, M. L., Fink, H. A., Stone, K. L., Barrett-Connor, E., … Hoffman, A. R. (2014). ASSOCIATION BETWEEN THYROID FUNCTION AND OBJECTIVE AND SUBJECTIVE SLEEP QUALITY IN OLDER MEN: THE OSTEOPOROTIC FRACTURES IN MEN (MROS) STUDY. ENDOCRINE PRACTICE, 20(6), 576–86. -
Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions.
Durruthy-Durruthy, J., Briggs, S. F., Awe, J., Ramathal, C. Y., Karumbayaram, S., Lee, P. C., … Sebastiano, V. (2014). Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions. PloS One, 9(4). -
Association Between Thyroid Function and Objective and Subjective Sleep Quality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study.
Akatsu, H., Ewing, S. K., Stefanick, M. L., Fink, H. A., Stone, K. L., Barrett-Connor, E., … For The Osteoporotic Fractures In Men MrOS Research Group. (2014). Association Between Thyroid Function and Objective and Subjective Sleep Quality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study. Endocrine Practice , 20(6), 576–86. -
An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies.
Wang, H., Li, W., Guo, R., Sun, J., Cui, J., Wang, G., … Hu, J.-F. F. (2014). An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies. International Journal of Cancer. Journal International Du Cancer. -
A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies.
Sun, J., Li, W., Sun, Y., Yu, D., Wen, X., Wang, H., … Hu, J.-F. (2014). A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies. Nucleic Acids Research, 42(15), 9588–9601. -
Targeted gene suppression by inducing de novo DNA methylation in the gene promoter.
Ma, A.-N., Wang, H., Guo, R., Wang, Y.-X., Li, W., Cui, J., … Hu, J.-F. (2014). Targeted gene suppression by inducing de novo DNA methylation in the gene promoter. Epigenetics & Chromatin, 7, 20-? -
Vitamin D Deficiency in Older Men
Orwoll, E., Nielson, C. M., Marshall, L. M., Lambert, L., Holton, K. F., Hoffman, A. R., … Cauley, J. A. (2009). Vitamin D Deficiency in Older Men. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 94(4), 1214–22. -
Serum 25-Hydroxyvitamin D and the Risk of Hip and Nonspine Fractures in Older Men
Cauley, J. A., Parimi, N., Ensrud, K. E., Bauer, D. C., Cawthon, P. M., Cummings, S. R., … Orwoll, E. (2010). Serum 25-Hydroxyvitamin D and the Risk of Hip and Nonspine Fractures in Older Men. JOURNAL OF BONE AND MINERAL RESEARCH, 25(3), 545–553. -
Long Noncoding RNA HOTAIR as an Independent Prognostic Marker in Cancer: A Meta-Analysis
Zhang, S., Chen, S., Yang, G., Gu, F., Li, M., Zhong, B., … Chen, M. (2014). Long Noncoding RNA HOTAIR as an Independent Prognostic Marker in Cancer: A Meta-Analysis. PLOS ONE, 9(8). -
An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies
Wang, H., Li, W., Guo, R., Sun, J., Cui, J., Wang, G., … Hu, J.-F. (2014). An intragenic long noncoding RNA interacts epigenetically with the RUNX1 promoter and enhancer chromatin DNA in hematopoietic malignancies. INTERNATIONAL JOURNAL OF CANCER, 135(12), 2783–94. -
Circulating Vitamin D, Supplement Use, and Cardiovascular Disease Risk: The MrOS Sleep Study
Bajaj, A., Stone, K. L., Peters, K., Parimi, N., Barrett-Connor, E., Bauer, D., … Schernhammer, E. S. (2014). Circulating Vitamin D, Supplement Use, and Cardiovascular Disease Risk: The MrOS Sleep Study. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 99(9), 3256–62. -
Aberrant allele-switch imprinting of a novel IGF1R intragenic antisense non-coding RNA in breast cancers
Kang, L., Sun, J., Wen, X., Cui, J., Wang, G., Hoffman, A. R., … Li, W. (2015). Aberrant allele-switch imprinting of a novel IGF1R intragenic antisense non-coding RNA in breast cancers. EUROPEAN JOURNAL OF CANCER, 51(2), 260–70. -
Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C
Ay, F., Vu, T. H., Zeitz, M. J., Varoquaux, N., Carette, J. E., Vert, J.-P., … Noble, W. S. (2015). Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C. BMC GENOMICS, 16. -
Associated Chromosome Trap for Identifying Long-range DNA Interactions
Ling, J., & Hoffman, A. R. (2011). Associated Chromosome Trap for Identifying Long-range DNA Interactions. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (50). -
Treatment of the adult growth hormone deficiency syndrome: Directions for future research
Hoffman, A. R. (2005). Treatment of the adult growth hormone deficiency syndrome: Directions for future research. Presented at the 18th Annual National Cooperative Growth Study/5th Annual National Cooperative Somatropin Surveillance Investigator Meeting, PHOENIX,AZ: CHURCHILL LIVINGSTONE. -
INTERACTION OF IGF WITH THE HYPOTHALAMUS AND PITUITARY
Rosenfeld, R. G., OCRANT, I., Valentino, K. L., & Hoffman, A. R. (1989). INTERACTION OF IGF WITH THE HYPOTHALAMUS AND PITUITARY. Presented at the SYMP ON MOLECULAR AND CELLULAR BIOLOGY OF INSULIN-LIKE GROWTH FACTORS AND THEIR RECEPTORS, GAINESVILLE,FL: PLENUM PRESS DIV PLENUM PUBLISHING CORP. -
EFFECTS OF RECOMBINANT INSULIN-LIKE GROWTH-FACTOR-I AND GROWTH-HORMONE ON BONE TURNOVER IN ELDERLY WOMEN
GHIRON, L. J., Thompson, J. L., Holloway, L., Hintz, R. L., Butterfield, G. E., Hoffman, A. R., & Marcus, R. (1995). EFFECTS OF RECOMBINANT INSULIN-LIKE GROWTH-FACTOR-I AND GROWTH-HORMONE ON BONE TURNOVER IN ELDERLY WOMEN. JOURNAL OF BONE AND MINERAL RESEARCH, 10(12), 1844–1852. -
Association of a high mobility group gene (HMGA2) variant with bone mineral density
Kuipers, A., Zhang, Y., Cauley, J. A., Nestlerode, C. S., Chu, Y., Bunker, C. H., … Zmuda, J. M. (2009). Association of a high mobility group gene (HMGA2) variant with bone mineral density. BONE, 45(2), 295–300. -
The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (Nutropin Depot) in GH-deficient adults
Cook, D. M., Biller, B. M. K., Vance, M. L., Hoffman, A. R., Phillips, L. S., Ford, K. M., … Fielder, P. J. (2002). The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (Nutropin Depot) in GH-deficient adults. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(10), 4508–14. -
High-Density Association Study of 383 Candidate Genes for Volumetric BMD at the Femoral Neck and Lumbar Spine Among Older Men
Yerges, L. M., Klei, L., Cauley, J. A., Roeder, K., Kammerer, C. M., Moffett, S. P., … Zmuda, J. M. (2009). High-Density Association Study of 383 Candidate Genes for Volumetric BMD at the Femoral Neck and Lumbar Spine Among Older Men. JOURNAL OF BONE AND MINERAL RESEARCH, 24(12), 2039–2049. -
Candidate Gene Analysis of Femoral Neck Trabecular and Cortical Volumetric Bone Mineral Density in Older Men
Yerges, L. M., Klei, L., Cauley, J. A., Roeder, K., Kammerer, C. M., Ensrud, K. E., … Zmuda, J. M. (2010). Candidate Gene Analysis of Femoral Neck Trabecular and Cortical Volumetric Bone Mineral Density in Older Men. JOURNAL OF BONE AND MINERAL RESEARCH, 25(2), 330–338. -
Transdermal testosterone gel: pharmacokinetics, efficacy of dosing and application site in hypogonadal men
Meikle, A. W., Matthias, D., & Hoffman, A. R. (2004). Transdermal testosterone gel: pharmacokinetics, efficacy of dosing and application site in hypogonadal men. BJU INTERNATIONAL, 93(6), 789–795. -
The Association of Bone Mineral Density with Prostate Cancer Risk in the Osteoporotic Fractures in Men (MrOS) Study
Farhat, G. N., Taioli, E., Cauley, J. A., Zmuda, J. M., Orwoll, E., Bauer, D. C., … Bunker, C. H. (2009). The Association of Bone Mineral Density with Prostate Cancer Risk in the Osteoporotic Fractures in Men (MrOS) Study. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 18(1), 148–154. -
Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men
Zmuda, J. M., Yerges-Armstrong, L. M., Moffett, S. P., Klei, L., Kammerer, C. M., Roeder, K., … Orwoll, E. S. (2011). Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men. OSTEOPOROSIS INTERNATIONAL, 22(4), 1079–1090. -
REGULATION OF INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN EXPRESSION BY THYROID-HORMONE IN RAT GH3 PITUITARY-TUMOR CELLS
Ceda, G. P., Fielder, P. J., Donovan, S. M., Rosenfeld, R. G., & Hoffman, A. R. (1992). REGULATION OF INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN EXPRESSION BY THYROID-HORMONE IN RAT GH3 PITUITARY-TUMOR CELLS. ENDOCRINOLOGY, 130(3), 1483–1489. -
INTERACTIONS OF GROWTH-HORMONE AND PARATHYROID-HORMONE IN RENAL PHOSPHATE, CALCIUM, AND CALCITRIOL METABOLISM AND BONE REMODELING IN POSTMENOPAUSAL WOMEN
Lieberman, S. A., Holloway, L., Marcus, R., & Hoffman, A. R. (1994). INTERACTIONS OF GROWTH-HORMONE AND PARATHYROID-HORMONE IN RENAL PHOSPHATE, CALCIUM, AND CALCITRIOL METABOLISM AND BONE REMODELING IN POSTMENOPAUSAL WOMEN. JOURNAL OF BONE AND MINERAL RESEARCH, 9(11), 1723–1728. -
Fracture risk in diabetic elderly men: the MrOS study
Napoli, N., Strotmeyer, E. S., Ensrud, K. E., Sellmeyer, D. E., Bauer, D. C., Hoffman, A. R., … Schwartz, A. V. (2014). Fracture risk in diabetic elderly men: the MrOS study. DIABETOLOGIA, 57(10), 2057–2065. -
Prevalence, severity, and health correlates of lower urinary tract symptoms among older men: The MrOS study
Taylor, B. C., Wilt, T. J., Fink, H. A., Lambert, L. C., Marshall, L. M., Hoffman, A. R., … Orwoll, E. S. (2006). Prevalence, severity, and health correlates of lower urinary tract symptoms among older men: The MrOS study. UROLOGY, 68(4), 804–809. -
THE INSULIN-LIKE GROWTH-FACTOR-I GENERATION TEST - RESISTANCE TO GROWTH-HORMONE WITH AGING AND ESTROGEN REPLACEMENT THERAPY
Lieberman, S. A., Mitchell, A. M., Marcus, R., Hintz, R. L., & Hoffman, A. R. (1994). THE INSULIN-LIKE GROWTH-FACTOR-I GENERATION TEST - RESISTANCE TO GROWTH-HORMONE WITH AGING AND ESTROGEN REPLACEMENT THERAPY. HORMONE AND METABOLIC RESEARCH, 26(5), 229–233. -
INSULIN AND INSULIN-LIKE GROWTH-FACTOR (SOMATOMEDIN) RECEPTORS ON CLONED RAT PITUITARY-TUMOR CELLS
Rosenfeld, R. G., Ceda, G., Cutler, C. W., DOLLAR, L. A., & Hoffman, A. R. (1985). INSULIN AND INSULIN-LIKE GROWTH-FACTOR (SOMATOMEDIN) RECEPTORS ON CLONED RAT PITUITARY-TUMOR CELLS. ENDOCRINOLOGY, 117(5), 2008–2016. -
Recombinant human growth hormone, but not insulin-like growth factor-I, enhances central fat loss in postmenopausal women undergoing a diet and exercise program
Taaffe, D. R., Thompson, J. L., Butterfield, G. E., Hoffman, A. R., & Marcus, R. (2001). Recombinant human growth hormone, but not insulin-like growth factor-I, enhances central fat loss in postmenopausal women undergoing a diet and exercise program. HORMONE AND METABOLIC RESEARCH, 33(3), 156–162. -
THE GROWTH-HORMONE (GH)-RELEASING HORMONE (GHRH)-GH-SOMATOMEDIN AXIS - EVIDENCE FOR RAPID INHIBITION OF GHRH-ELICITED GH RELEASE BY INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II
Ceda, G. P., Davis, R. G., Rosenfeld, R. G., & Hoffman, A. R. (1987). THE GROWTH-HORMONE (GH)-RELEASING HORMONE (GHRH)-GH-SOMATOMEDIN AXIS - EVIDENCE FOR RAPID INHIBITION OF GHRH-ELICITED GH RELEASE BY INSULIN-LIKE GROWTH FACTOR-I AND FACTOR-II. ENDOCRINOLOGY, 120(4), 1658–1662. -
Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury
Hernandez, F., Wu, L. C., Yip, M. C., Laksari, K., Hoffman, A. R., Lopez, J. R., … Camarillo, D. B. (2015). Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury. ANNALS OF BIOMEDICAL ENGINEERING, 43(8), 1918–34. -
Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis
Fan, J., Xing, Y., Wen, X., Jia, R., Ni, H., He, J., … Fan, X. (2015). Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis. GENOME BIOLOGY, 16. -
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: MANAGEMENT OF ACROMEGALY PATIENTS: MANAGEMENT OF ACROMEGALY PATIENTS: WHAT IS THE ROLE OF PRE-OPERATIVE MEDICAL THERAPY?
Fleseriu, M., Hoffman, A. R., & Katznelson, L. (2015). AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: MANAGEMENT OF ACROMEGALY PATIENTS: MANAGEMENT OF ACROMEGALY PATIENTS: WHAT IS THE ROLE OF PRE-OPERATIVE MEDICAL THERAPY? ENDOCRINE PRACTICE, 21(6), 668–673. -
GLUCOCORTICOID MODULATION OF CORTICOTROPIN-RELEASING FACTOR DESENSITIZATION IN CULTURED RAT ANTERIOR-PITUITARY-CELLS
Ceda, G. P., & Hoffman, A. R. (1986). GLUCOCORTICOID MODULATION OF CORTICOTROPIN-RELEASING FACTOR DESENSITIZATION IN CULTURED RAT ANTERIOR-PITUITARY-CELLS. ENDOCRINOLOGY, 118(1), 58–62. -
GROWTH HORMONE-RELEASING FACTOR DESENSITIZATION IN RAT ANTERIOR-PITUITARY CELLS-INVITRO
Ceda, G. P., & Hoffman, A. R. (1985). GROWTH HORMONE-RELEASING FACTOR DESENSITIZATION IN RAT ANTERIOR-PITUITARY CELLS-INVITRO. ENDOCRINOLOGY, 116(4), 1334–1340. -
GLUCOCORTICOID MODULATION OF GROWTH-HORMONE SECRETION INVITRO - EVIDENCE FOR A BIPHASIC EFFECT ON GH-RELEASING HORMONE MEDIATED RELEASE
Ceda, G. P., Davis, R. G., & Hoffman, A. R. (1987). GLUCOCORTICOID MODULATION OF GROWTH-HORMONE SECRETION INVITRO - EVIDENCE FOR A BIPHASIC EFFECT ON GH-RELEASING HORMONE MEDIATED RELEASE. ACTA ENDOCRINOLOGICA, 114(4), 465–469. -
SECRETION OF ALPHA-SUBUNIT AND INTACT GONADOTROPINS AFTER SURGICAL AND CHEMICAL CASTRATION
Ceda, G. P., Denti, L., Ceresini, G., Cortellini, P., Banchini, A., Frattini, A., … Valenti, G. (1990). SECRETION OF ALPHA-SUBUNIT AND INTACT GONADOTROPINS AFTER SURGICAL AND CHEMICAL CASTRATION. HORMONE AND METABOLIC RESEARCH, 22(3), 179–182. -
The insulin-like growth factor axis and plasma lipid levels in the elderly
Ceda, G. P., Dall'Aglio, E., Magnacavallo, A., Vargas, N., Fontana, V., Maggio, M., … Hoffman, A. R. (1998). The insulin-like growth factor axis and plasma lipid levels in the elderly. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 83(2), 499–502. -
CALCITONIN INHIBITION OF GROWTH HORMONE-RELEASING HORMONE-INDUCED GH SECRETION IN NORMAL MEN
Ceda, G. P., Denti, L., Ceresini, G., Rastelli, G., Dotti, C., Cavalieri, S., … Hoffman, A. R. (1989). CALCITONIN INHIBITION OF GROWTH HORMONE-RELEASING HORMONE-INDUCED GH SECRETION IN NORMAL MEN. ACTA ENDOCRINOLOGICA, 120(4), 416–422. -
DIMINISHED PITUITARY-RESPONSIVENESS TO GROWTH HORMONE-RELEASING FACTOR IN AGING MALE-RATS
Ceda, G. P., Valenti, G., BUTTURINI, U., & Hoffman, A. R. (1986). DIMINISHED PITUITARY-RESPONSIVENESS TO GROWTH HORMONE-RELEASING FACTOR IN AGING MALE-RATS. ENDOCRINOLOGY, 118(5), 2109–2114. -
Growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in the elderly: Clinical trial results
Ceda, G. P., Dall'Aglio, E., Salimbeni, I., Rocci, A., Corradi, F., Mazzoni, S., … Hoffman, A. R. (2002). Growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in the elderly: Clinical trial results. ARCHIVES OF GERONTOLOGY AND GERIATRICS, 81–92. -
GROWTH-HORMONE THERAPY IN THE ELDERLY - IMPLICATIONS FOR THE AGING BRAIN
Hoffman, A. R., Lieberman, S. A., & Ceda, G. P. (1992). GROWTH-HORMONE THERAPY IN THE ELDERLY - IMPLICATIONS FOR THE AGING BRAIN. PSYCHONEUROENDOCRINOLOGY, 17(4), 327–333. -
CORTICOTROPIN-RELEASING FACTOR DESENSITIZATION OF ADRENOCORTICOTROPIC HORMONE-RELEASE IS AUGMENTED BY ARGININE VASOPRESSIN
Hoffman, A. R., Ceda, G., & Reisine, T. D. (1985). CORTICOTROPIN-RELEASING FACTOR DESENSITIZATION OF ADRENOCORTICOTROPIC HORMONE-RELEASE IS AUGMENTED BY ARGININE VASOPRESSIN. JOURNAL OF NEUROSCIENCE, 5(1), 234–242. -
EFFECTS OF CYTIDINE 5'-DIPHOSPHOCHOLINE ADMINISTRATION ON BASAL AND GROWTH HORMONE-RELEASING HORMONE-INDUCED GROWTH-HORMONE SECRETION IN ELDERLY SUBJECTS
Ceda, G. P., Ceresini, G., Denti, L., Magnani, D., Marchini, L., Valenti, G., & Hoffman, A. R. (1991). EFFECTS OF CYTIDINE 5'-DIPHOSPHOCHOLINE ADMINISTRATION ON BASAL AND GROWTH HORMONE-RELEASING HORMONE-INDUCED GROWTH-HORMONE SECRETION IN ELDERLY SUBJECTS. ACTA ENDOCRINOLOGICA, 124(5), 516–520. -
Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly
Denti, L., Annoni, V., Cattadori, E., Salvagnini, M. A., Visioli, S., Merli, M. F., … Ceda, G. P. (2004). Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly. AMERICAN JOURNAL OF MEDICINE, 117(5), 312–317. -
THE EFFECTS OF AGING ON THE SECRETION OF THE COMMON ALPHA-SUBUNIT OF THE GLYCOPROTEIN HORMONES IN MEN
Ceda, G. P., Denti, L., Ceresini, G., TORSIGLIERI, W., Hoffman, A. R., & Valenti, G. (1991). THE EFFECTS OF AGING ON THE SECRETION OF THE COMMON ALPHA-SUBUNIT OF THE GLYCOPROTEIN HORMONES IN MEN. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 39(4), 353–358. -
EFFECT OF RECOMBINANT HUMAN GROWTH-HORMONE ON THE MUSCLE STRENGTH RESPONSE TO RESISTANCE EXERCISE IN ELDERLY MEN
Taaffe, D. R., Pruitt, L., Reim, J., Hintz, R. L., Butterfield, G., Hoffman, A. R., & Marcus, R. (1994). EFFECT OF RECOMBINANT HUMAN GROWTH-HORMONE ON THE MUSCLE STRENGTH RESPONSE TO RESISTANCE EXERCISE IN ELDERLY MEN. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 79(5), 1361–1366. -
DESENSITIZATION OF CORTICOTROPIN-RELEASING FACTOR RECEPTORS
Reisine, T., & Hoffman, A. (1983). DESENSITIZATION OF CORTICOTROPIN-RELEASING FACTOR RECEPTORS. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 111(3), 919–925. -
Effect of rhGH and rhIGF-I treatment on protein utilization in elderly women
Butterfield, G. E., Thompson, J., Rennie, M. J., Marcus, R., Hintz, R. L., & Hoffman, A. R. (1997). Effect of rhGH and rhIGF-I treatment on protein utilization in elderly women. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 272(1), E94–E99. -
ANABOLIC EFFECTS OF RECOMBINANT INSULIN-LIKE GROWTH FACTOR-I IN CACHECTIC PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME
Lieberman, S. A., Butterfield, G. E., Harrison, D., & Hoffman, A. R. (1994). ANABOLIC EFFECTS OF RECOMBINANT INSULIN-LIKE GROWTH FACTOR-I IN CACHECTIC PATIENTS WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 78(2), 404–410. -
Growth hormone deficiency in adults: Characteristics and response to growth hormone replacement
Lieberman, S. A., & Hoffman, A. R. (1996). Growth hormone deficiency in adults: Characteristics and response to growth hormone replacement. JOURNAL OF PEDIATRICS, 128(5), S58–S60. -
ABERRANT PRODUCTION AND REGULATION OF PROOPIOMELANOCORTIN-DERIVED PEPTIDES IN ECTOPIC CUSHINGS-SYNDROME
Roth, K. A., NEWELL, D. C., Dorin, R. I., Eberwine, J. H., & Hoffman, A. R. (1988). ABERRANT PRODUCTION AND REGULATION OF PROOPIOMELANOCORTIN-DERIVED PEPTIDES IN ECTOPIC CUSHINGS-SYNDROME. HORMONE AND METABOLIC RESEARCH, 20(4), 225–29. -
MESSENGER-RNA STRUCTURE, INSITU, AS ASSESSED BY MICROSCOPIC TECHNIQUES
Eberwine, J. H., Spencer, C., NEWELL, D., & Hoffman, A. R. (1993). MESSENGER-RNA STRUCTURE, INSITU, AS ASSESSED BY MICROSCOPIC TECHNIQUES. MICROSCOPY RESEARCH AND TECHNIQUE, 25(1), 19–28. -
THE EFFECTS OF RECOMBINANT HUMAN INSULIN-LIKE GROWTH-FACTOR-I AND GROWTH-HORMONE ON BODY-COMPOSITION IN ELDERLY WOMEN
Thompson, J. L., Butterfield, G. E., Marcus, R., Hintz, R. L., VanLoan, M., Ghiron, L., & Hoffman, A. R. (1995). THE EFFECTS OF RECOMBINANT HUMAN INSULIN-LIKE GROWTH-FACTOR-I AND GROWTH-HORMONE ON BODY-COMPOSITION IN ELDERLY WOMEN. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 80(6), 1845–1852. -
Targeted gene suppression by inducing de novo DNA methylation in the gene promoter.
Ma, A.-N., Wang, H., Guo, R., Wang, Y.-X., Li, W., Cui, J., … Hu, J.-F. (2014). Targeted gene suppression by inducing de novo DNA methylation in the gene promoter. Epigenetics & Chromatin, 7, 20-? -
Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C.
Ay, F., Vu, T. H., Zeitz, M. J., Varoquaux, N., Carette, J. E., Vert, J.-P., … Noble, W. S. (2015). Identifying multi-locus chromatin contacts in human cells using tethered multiple 3C. BMC Genomics, 16, 121-? -
Status of long-acting-growth hormone preparations-2015
Hoybye, C., Cohen, P., Hoffman, A. R., Ross, R., Biller, B. M. K., & Christiansen, J. S. (2015). Status of long-acting-growth hormone preparations-2015. GROWTH HORMONE & IGF RESEARCH, 25(5), 201–6. -
Greater Skeletal Muscle Fat Infiltration Is Associated With Higher All-Cause and Cardiovascular Mortality in Older Men
Miljkovic, I., Kuipers, A. L., Cauley, J. A., Prasad, T., Lee, C. G., Ensrud, K. E., … Zmuda, J. M. (2015). Greater Skeletal Muscle Fat Infiltration Is Associated With Higher All-Cause and Cardiovascular Mortality in Older Men. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 70(9), 1133–40. -
Subclinical Thyroid Dysfunction and Frailty Among Older Men
Virgini, V. S., Rodondi, N., Cawthon, P. M., Harrison, S. L., Hoffman, A. R., Orwoll, E. S., … Bauer, D. C. (2015). Subclinical Thyroid Dysfunction and Frailty Among Older Men. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 100(12), 4524–4532. -
Evaluation of the Usefulness of Consensus Definitions of Sarcopenia in Older Men: Results from the Observational Osteoporotic Fractures in Men Cohort Study
Cawthon, P. M., Blackwell, T. L., Cauley, J., Kado, D. M., Barrett-Connor, E., Lee, C. G., … Orwoll, E. S. (2015). Evaluation of the Usefulness of Consensus Definitions of Sarcopenia in Older Men: Results from the Observational Osteoporotic Fractures in Men Cohort Study. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 63(11), 2247–59. -
Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells
Wang, H., Ge, S. F., Qian, G., Li, W., Cui, J., Wang, G., … Hu, J.-F. (2015). Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells. EXPERIMENTAL CELL RESEARCH, 338(2), 214–21. -
A Novel Inherited Mutation in PRKAR1A Abrogates PreRNA Splicing in a Carney Complex Family
Sun, Y., Chen, X., Sun, J., Wen, X., Liu, X., Zhang, Y., … Gao, Y. (2015). A Novel Inherited Mutation in PRKAR1A Abrogates PreRNA Splicing in a Carney Complex Family. CANADIAN JOURNAL OF CARDIOLOGY, 31(11), 1393–1401. -
GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults
Allen, D. B., Backeljauw, P., Bidlingmaier, M., Biller, B. M. K., Boguszewski, M., Burman, P., … Thorner, M. (2016). GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 174(2), P1–P9. -
Sleep Disordered Breathing and Risk of Stroke in Older Community-Dwelling Men
Stone, K. L., Blackwell, T. L., Ancoli-Israel, S., Barrett-Connor, E., Bauer, D. C., Cauley, J. A., … Redline, S. (2016). Sleep Disordered Breathing and Risk of Stroke in Older Community-Dwelling Men. SLEEP, 39(3), 531–40. -
Sex hormones, sex hormone binding globulin, and vertebral fractures in older men
Cawthon, P. M., Schousboe, J. T., Harrison, S. L., Ensrud, K. E., Black, D., Cauley, J. A., … Orwoll, E. S. (2016). Sex hormones, sex hormone binding globulin, and vertebral fractures in older men. BONE, 84, 271–78. -
Converting Skin Fibroblasts into Hepatic-like Cells by Transient Programming.
Zhu, X.-Q., Pan, X.-H., Yao, L., Li, W., Cui, J., Wang, G., … Hu, J.-F. (2016). Converting Skin Fibroblasts into Hepatic-like Cells by Transient Programming. Journal of Cellular Biochemistry, 117(3), 589–98. -
Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations
Christiansen, J. S., Backeljauw, P. F., Bidlingmaier, M., Biller, B. M. K., Boguszewski, M. C. S., Casanueva, F. F., … Yuen, K. (2016). Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 174(6), C1–C8. -
Bone Density Loss Is Associated With Blood Cell Counts.
Valderrábano, R. J., Lui, L.-Y., Lee, J., Cummings, S. R., Orwoll, E. S., Hoffman, A. R., & Wu, J. Y. (2016). Bone Density Loss Is Associated With Blood Cell Counts. Journal of Bone and Mineral Research . -
AACE/ACE DISEASE STATE CLINICAL REVIEW: MEDICAL MANAGEMENT OF CUSHING DISEASE
Hamrahian, A. H., Yuen, K. C. J., & Hoffman, A. R. (2014). AACE/ACE DISEASE STATE CLINICAL REVIEW: MEDICAL MANAGEMENT OF CUSHING DISEASE. ENDOCRINE PRACTICE, 20(7), 746–757. -
Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults
Giustina, A., Barkan, A., Chanson, P., Grossman, A., Hoffman, A., Ghigo, E., … Melmed, S. (2008). Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 31(9), 820–38. -
Diagnosis and Treatment of Hyperprolactinemia: An Endocrine Society Clinical Practice Guideline
Melmed, S., Casanueva, F. F., Hoffman, A. R., Kleinberg, D. L., Montori, V. M., Schlechte, J. A., & Wass, J. A. H. (2011). Diagnosis and Treatment of Hyperprolactinemia: An Endocrine Society Clinical Practice Guideline. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 96(2), 273–288. -
The impact of hypopituitarism on function and performance in subjects with recent history of traumatic brain injury and aneurysmal subarachnoid haemorrhage
Srinivasan, L., Roberts, B., Bushnik, T., Englander, J., Spain, D. A., Steinberg, G. K., … Katznelson, L. (2009). The impact of hypopituitarism on function and performance in subjects with recent history of traumatic brain injury and aneurysmal subarachnoid haemorrhage. BRAIN INJURY, 23(7-8), 639–48. -
Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells
Zhao, X., Liu, X., Wang, G., Wen, X., Zhang, X., Hoffman, A. R., … Cui, J. (2016). Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells. ONCOTARGET, 7(32), 51349–64. -
Serum 25-hydroxyvitamin D level and incident type 2 diabetes in older men, the Osteoporotic Fractures in Men (MrOS) study
Napoli, N., Schafer, A. L., Lui, L.-Y., Cauley, J. A., Strotmeyer, E. S., Le Blanc, E. S., … Schwartz, A. V. (2016). Serum 25-hydroxyvitamin D level and incident type 2 diabetes in older men, the Osteoporotic Fractures in Men (MrOS) study. BONE, 90, 181–84. -
When a gold standard isn't so golden: Lack of prediction of subjective sleep quality from sleep polysomnography.
Kaplan, K. A., Hirshman, J., Hernandez, B., Stefanick, M. L., Hoffman, A. R., Redline, S., … Zeitzer, J. M. (2017). When a gold standard isn't so golden: Lack of prediction of subjective sleep quality from sleep polysomnography. Biological Psychology, 123, 37–46. -
Risk Factors for Hip Fracture in Older Men: The Osteoporotic Fractures in Men Study (MrOS).
Cauley, J. A., Cawthon, P. M., Peters, K. E., Cummings, S. R., Ensrud, K. E., Bauer, D. C., … Orwoll, E. S. (2016). Risk Factors for Hip Fracture in Older Men: The Osteoporotic Fractures in Men Study (MrOS). Journal of Bone and Mineral Research , 31(10), 1810–19. -
Thyroid Function Variations Within the Reference Range Do Not Affect Quality of Life, Mood, or Cognitive Function in Community-Dwelling Older Men.
Samuels, M. H., Kaimal, R., Waring, A., Fink, H. A., Yaffe, K., Hoffman, A. R., … Bauer, D. (2016). Thyroid Function Variations Within the Reference Range Do Not Affect Quality of Life, Mood, or Cognitive Function in Community-Dwelling Older Men. Thyroid , 26(9), 1185–94. -
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: UPDATE ON GROWTH HORMONE STIMULATION TESTING AND PROPOSED REVISED CUT-POINT FOR THE GLUCAGON STIMULATION TEST IN THE DIAGNOSIS OF ADULT GROWTH HORMONE DEFICIENCY
Yuen, K. C. J., Tritos, N. A., Samson, S. L., Hoffman, A. R., & Katznelson, L. (2016). AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: UPDATE ON GROWTH HORMONE STIMULATION TESTING AND PROPOSED REVISED CUT-POINT FOR THE GLUCAGON STIMULATION TEST IN THE DIAGNOSIS OF ADULT GROWTH HORMONE DEFICIENCY. ENDOCRINE PRACTICE, 22(10), 1235–44. -
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: DIAGNOSIS OF RECURRENCE IN CUSHING DISEASE
Fleseriu, M., Hamrahian, A. H., Hoffman, A. R., Kelly, D. F., & Katznelson, L. (2016). AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: DIAGNOSIS OF RECURRENCE IN CUSHING DISEASE. ENDOCRINE PRACTICE, 22(12), 1436–48. -
CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors.
Zhang, Y., Hu, J.-F., Wang, H., Cui, J., Gao, S., Hoffman, A. R., & Li, W. (2016). CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors. Oncotarget. -
Older Men with Anemia Have Increased Fracture Risk Independent of Bone Mineral Density.
Valderrábano, R. J., Lee, J., Lui, L.-Y., Hoffman, A. R., Cummings, S. R., Orwoll, E. S., & Wu, J. Y. (2017). Older Men with Anemia Have Increased Fracture Risk Independent of Bone Mineral Density. Journal of Clinical Endocrinology and Metabolism. -
A Case Report of Hypoglycemia and Hypogammaglobulinemia: DAVID syndrome in a patient with a novel NFKB2 mutation.
Lal, R. A., Bachrach, L. K., Hoffman, A. R., Inlora, J., Rego, S., Snyder, M. P., & Lewis, D. B. (2017). A Case Report of Hypoglycemia and Hypogammaglobulinemia: DAVID syndrome in a patient with a novel NFKB2 mutation. Journal of Clinical Endocrinology and Metabolism. -
The Limited Clinical Utility of Testosterone, Estradiol, and Sex Hormone Binding Globulin Measurements in the Prediction of Fracture Risk and Bone Loss in Older Men
Orwoll, E. S., Lapidus, J., Wang, P. Y., Vandenput, L., Hoffman, A., Fink, H. A., … Ohlsson, C. (2017). The Limited Clinical Utility of Testosterone, Estradiol, and Sex Hormone Binding Globulin Measurements in the Prediction of Fracture Risk and Bone Loss in Older Men. JOURNAL OF BONE AND MINERAL RESEARCH, 32(3), 633–40. -
Bone Density Loss Is Associated With Blood Cell Counts
Valderrabano, R. J., Lui, L.-Y., Lee, J., Cummings, S. R., Orwoll, E. S., Hoffman, A. R., & Wu, J. Y. (2017). Bone Density Loss Is Associated With Blood Cell Counts. JOURNAL OF BONE AND MINERAL RESEARCH, 32(2), 212–20. -
Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells
Yu, D., Du, Z., Pian, L., Li, T., Wen, X., Li, W., … Hu, J.-F. (2017). Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells. STEM CELLS INTERNATIONAL. -
Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study.
Laddu, D. R., Cawthon, P. M., Parimi, N., Hoffman, A. R., Orwoll, E., Miljkovic, I., & Stefanick, M. L. (2017). Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study. BMC Geriatrics, 17(1), 119-? -
Daily Patterns of Accelerometer Activity Predict Changes in Sleep, Cognition, and Mortality in Older Men.
Zeitzer, J. M., Blackwell, T., Hoffman, A. R., Cummings, S., Ancoli-Israel, S., & Stone, K. (2017). Daily Patterns of Accelerometer Activity Predict Changes in Sleep, Cognition, and Mortality in Older Men. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. -
Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping.
Morgan, S. L., Mariano, N. C., Bermudez, A., Arruda, N. L., Wu, F., Luo, Y., … Wang, K. C. (2017). Manipulation of nuclear architecture through CRISPR-mediated chromosomal looping. Nature Communications, 8, 15993. -
Serum Sodium and Cognition in Older Community-Dwelling Men
Nowak, K. L., Yaffe, K., Orwoll, E. S., Ix, J. H., You, Z., Barrett-Connor, E., … Chonchol, M. (2018). Serum Sodium and Cognition in Older Community-Dwelling Men. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 13(3), 366–74. -
Vertebral Fracture Risk in Diabetic Elderly Men: The MrOS Study
Napoli, N., Schwartz, A. V., Schafer, A. L., Vittinghoff, E., Cawthon, P. M., Parimi, N., … Black, D. M. (2018). Vertebral Fracture Risk in Diabetic Elderly Men: The MrOS Study. JOURNAL OF BONE AND MINERAL RESEARCH, 33(1), 63–69. -
Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study
Vandenput, L., Mellstrom, D., Laughlin, G. A., Cawthon, P. M., Cauley, J. A., Hoffman, A. R., … Ohlsson, C. (2017). Low Testosterone, but Not Estradiol, Is Associated With Incident Falls in Older Men: The International MrOS Study. JOURNAL OF BONE AND MINERAL RESEARCH, 32(6), 1174–81. -
Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors
Wang, H., Guo, R., Du, Z., Bai, L., Li, L., Cui, J., … Hu, J.-F. (2018). Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors. MOLECULAR THERAPY-NUCLEIC ACIDS, 11, 23–33. -
Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men
Eriksson, A. L., Perry, J. R. B., Coviello, A. D., Delgado, G. E., Ferrucci, L., Hoffman, A. R., … Ohlsson, C. (2018). Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 103(3), 991–1004. -
Clinical and Immunohistochemical Analysis of Clinically Non-functional Pituitary Neuroendocrine Tumors
Lavezo, J., Frankel, M., Balliu, B., Pan, J., Hoffman, A., Dodd, R., … Vogel, H. (2018). Clinical and Immunohistochemical Analysis of Clinically Non-functional Pituitary Neuroendocrine Tumors. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 77(6), 518. -
Growth Hormone Research Society perspective on biomarkers of GH action in children and adults
Johannsson, G., Bidlingmaier, M., Biller, B. M. K., Boguszewski, M., Casanueva, F. F., Chanson, P., … Jorgensen, J. O. L. (2018). Growth Hormone Research Society perspective on biomarkers of GH action in children and adults. ENDOCRINE CONNECTIONS, 7(3), R126–R134. -
Mitochondrial peptides modulate mitochondrial function during cellular senescence
Kim, S.-J., Mehta, H. H., Wan, J., Kuehnemann, C., Chen, J., Hu, J.-F., … Cohen, P. (2018). Mitochondrial peptides modulate mitochondrial function during cellular senescence. AGING-US, 10(6), 1239–56. -
Management of Incidental Pituitary Findings on CT, MRI, and F-18-Fluorodeoxyglucose PET: A White Paper of the ACR Incidental Findings Committee
Hoang, J. K., Hoffman, A. R., Gonzalez, R. G., Wintermark, M., Glenn, B. J., Pandharipande, P. V., … Seidenwurm, D. J. (2018). Management of Incidental Pituitary Findings on CT, MRI, and F-18-Fluorodeoxyglucose PET: A White Paper of the ACR Incidental Findings Committee. JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY, 15(7), 966–72. -
Associations Between Lean Mass, Muscle Strength and Power, and Skeletal Size, Density and Strength in Older Men
Chalhoub, D., Boudreau, R., Greenspan, S., Newman, A. B., Zmuda, J., Frank-Wilson, A. W., … Cauley, J. A. (2018). Associations Between Lean Mass, Muscle Strength and Power, and Skeletal Size, Density and Strength in Older Men. JOURNAL OF BONE AND MINERAL RESEARCH, 33(9), 1612–21. -
Targeting the IGF1R Pathway in Breast Cancer Using Antisense lncRNA-Mediated Promoter cis Competition
Pian, L., Wen, X., Kang, L., Li, Z., Nie, Y., Du, Z., … Hu, J.-F. (2018). Targeting the IGF1R Pathway in Breast Cancer Using Antisense lncRNA-Mediated Promoter cis Competition. MOLECULAR THERAPY-NUCLEIC ACIDS, 12, 105–17. -
Long-Acting Growth Hormone Preparations in the Treatment of Children.
Lal, R. A., & Hoffman, A. R. (2018). Long-Acting Growth Hormone Preparations in the Treatment of Children. Pediatric Endocrinology Reviews : PER, 16(Suppl 1), 162–67. -
Central Obesity and Visceral Adipose Tissue Are Not Associated With Incident Atherosclerotic Cardiovascular Disease Events in Older Men.
Schousboe, J. T., Kats, A. M., Langsetmo, L., Vo, T. N., Taylor, B. C., Schwartz, A. V., … Ensrud, K. E. (2018). Central Obesity and Visceral Adipose Tissue Are Not Associated With Incident Atherosclerotic Cardiovascular Disease Events in Older Men. Journal of the American Heart Association, 7(16), e009172. -
Psychological effects of Dopamine Agonist Treatment in Patients with Hyperprolactinemia and Prolactin Secreting Adenomas.
Ioachimescu, A. G., Fleseriu, M., Hoffman, A. R., Vaughan Iii, T. B., & Katznelson, L. (2018). Psychological effects of Dopamine Agonist Treatment in Patients with Hyperprolactinemia and Prolactin Secreting Adenomas. European Journal of Endocrinology. -
Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming.
Du, Z., Jia, L., Wang, Y., Wang, C., Wen, X., Chen, J., … Hu, J.-F. (2018). Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming. Scientific Data, 5, 180255. -
Associations of Joint Trajectories of Appendicular Lean Mass and Grip Strength with Risk of Non-Spine Fractures
Valderrabano, R., Parimi, N., Cawthon, P. M., Lee, J. S., Wu, J. Y., Hoffman, A. R., & Stefanick, M. L. (2018). Associations of Joint Trajectories of Appendicular Lean Mass and Grip Strength with Risk of Non-Spine Fractures. JOURNAL OF BONE AND MINERAL RESEARCH. WILEY. -
Muscle mass assessed by D3Cr dilution and incident fractures in older men
Cawthon, P., Peters, K., Cummings, S., Orwoll, E., Hoffman, A., Ensrud, K., … Evans, W. (2018). Muscle mass assessed by D3Cr dilution and incident fractures in older men. JOURNAL OF BONE AND MINERAL RESEARCH, 33, 14. -
A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1.
Chen, N., Zhao, G., Yan, X., Lv, Z., Yin, H., Zhang, S., … Cui, J. (2018). A novel FLI1 exonic circular RNA promotes metastasis in breast cancer by coordinately regulating TET1 and DNMT1. Genome Biology, 19(1), 218. -
Growth hormone therapy in children; research and practice - A review.
Collett-Solberg, P. F., Jorge, A. A., Boguszewski, M. C., Miller, B. S., Choong, C. S., Cohen, P., … Saenger, P. (2018). Growth hormone therapy in children; research and practice - A review. Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 44, 20–32. -
Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury (vol 43, pg 1918, 2015)
Hernandez, F., Wu, L. C., Yip, M. C., Laksari, K., Hoffman, A. R., Lopez, J. R., … Camarillo, D. B. (2016). Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury (vol 43, pg 1918, 2015). ANNALS OF BIOMEDICAL ENGINEERING, 44(3), 828–29. -
Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury.
Hernandez, F., Wu, L. C., Yip, M. C., Laksari, K., Hoffman, A. R., Lopez, J. R., … Camarillo, D. B. (2015). Six Degree-of-Freedom Measurements of Human Mild Traumatic Brain Injury. Annals of Biomedical Engineering, 43(8), 1918–34. -
Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study.
Cawthon, P. M., Patel, S., Ewing, S. K., Lui, L.-Y. Y., Cauley, J. A., Lyons, J. G., … Orwoll, E. S. (2017). Bone Loss at the Hip and Subsequent Mortality in Older Men: The Osteoporotic Fractures in Men (MrOS) Study. JBMR Plus, 1(1), 31–35. -
Systematic Correlation Analyses of Circulating Tumor Cells with Clinical Variables and Tumor Markers in Lung Cancer Patients.
Wang, X., Ma, K., Yang, Z., Cui, J., He, H., Hoffman, A. R., … Li, W. (2017). Systematic Correlation Analyses of Circulating Tumor Cells with Clinical Variables and Tumor Markers in Lung Cancer Patients. Journal of Cancer, 8(15), 3099–3104. -
Targeting Jurkat T Lymphocyte Leukemia Cells by an Engineered Interferon-Alpha Hybrid Molecule.
Yu, D., Du, Z., Li, W., Chen, H., Ye, S., Hoffman, A. R., … Hu, J.-F. F. (2017). Targeting Jurkat T Lymphocyte Leukemia Cells by an Engineered Interferon-Alpha Hybrid Molecule. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 42(2), 519–29. -
The Limited Clinical Utility of Testosterone, Estradiol, and Sex Hormone Binding Globulin Measurements in the Prediction of Fracture Risk and Bone Loss in Older Men.
Orwoll, E. S., Lapidus, J., Wang, P. Y., Vandenput, L., Hoffman, A., Fink, H. A., … Ohlsson, C. (2017). The Limited Clinical Utility of Testosterone, Estradiol, and Sex Hormone Binding Globulin Measurements in the Prediction of Fracture Risk and Bone Loss in Older Men. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 32(3), 633–640. -
Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells.
Zhao, X., Liu, X., Wang, G., Wen, X., Zhang, X., Hoffman, A. R., … Cui, J. (2016). Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells. Oncotarget, 7(32), 51349–51364. -
Subclinical Thyroid Dysfunction and Frailty Among Older Men.
Virgini, V. S., Rodondi, N., Cawthon, P. M., Harrison, S. L., Hoffman, A. R., Orwoll, E. S., … Bauer, D. C. (2015). Subclinical Thyroid Dysfunction and Frailty Among Older Men. The Journal of Clinical Endocrinology and Metabolism, 100(12), 4524–32. -
AACE/ACE Disease State Clinical Review: Medical Management of Cushing Disease.
Hamrahian, A. H., Yuen, K. C., & Hoffman, A. R. (2014). AACE/ACE Disease State Clinical Review: Medical Management of Cushing Disease. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 20(7), 746–57. -
Genome-wide target interactome profiling reveals a novel EEF1A1 epigenetic pathway for oncogenic lncRNA MALAT1 in breast cancer
Li, X., Chen, N., Zhou, L., Wang, C., Wen, X., Jia, L., … Li, W. (2019). Genome-wide target interactome profiling reveals a novel EEF1A1 epigenetic pathway for oncogenic lncRNA MALAT1 in breast cancer. AMERICAN JOURNAL OF CANCER RESEARCH, 9(4), 714-+. -
Genome-wide target interactome profiling reveals a novel EEF1A1 epigenetic pathway for oncogenic lncRNA MALAT1 in breast cancer.
Li, X., Chen, N., Zhou, L., Wang, C., Wen, X., Jia, L., … Li, W. (2019). Genome-wide target interactome profiling reveals a novel EEF1A1 epigenetic pathway for oncogenic lncRNA MALAT1 in breast cancer. American Journal of Cancer Research, 9(4), 714–729. -
Granular Cell Pituitary Tumor in a Patient with Multiple Endocrine Neoplasia-1
Pendharkar, A., Lin, C.-Y., Born, D. E., Hoffman, A. R., & Dodd, R. L. (2019). Granular Cell Pituitary Tumor in a Patient with Multiple Endocrine Neoplasia-1. CUREUS, 11(4). -
Aberrant shuttling of long noncoding RNAs during the mitochondria-nuclear crosstalk in hepatocellular carcinoma cells
Zhao, Y., Liu, S., Zhou, L., Li, X., Meng, Y., Li, Y., … Cui, J. (2019). Aberrant shuttling of long noncoding RNAs during the mitochondria-nuclear crosstalk in hepatocellular carcinoma cells. AMERICAN JOURNAL OF CANCER RESEARCH, 9(5), 999-+. -
Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming
Du, Z., Jia, L., Wang, Y., Wang, C., Wen, X., Chen, J., … Hu, J.-F. (2018). Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming. SCIENTIFIC DATA, 5. -
Aberrant shuttling of long noncoding RNAs during the mitochondria-nuclear crosstalk in hepatocellular carcinoma cells.
Zhao, Y., Liu, S., Zhou, L., Li, X., Meng, Y., Li, Y., … Cui, J. (2019). Aberrant shuttling of long noncoding RNAs during the mitochondria-nuclear crosstalk in hepatocellular carcinoma cells. American Journal of Cancer Research, 9(5), 999–1008. -
Granular Cell Pituitary Tumor in a Patient with Multiple Endocrine Neoplasia-1.
Pendharkar, A. V., Lin, C.-Y. Y., Born, D. E., Hoffman, A. R., & Dodd, R. L. (2019). Granular Cell Pituitary Tumor in a Patient with Multiple Endocrine Neoplasia-1. Cureus, 11(4), e4541. -
Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing.
Zhang, S., Wang, Y., Jia, L., Wen, X., Zhonghua, D., Wang, C., … Cui, J. (2019). Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing. Genome Research. -
Profiling the epigenetic interplay of lncRNA RUNXOR and oncogenic RUNX1 in breast cancer cells by gene in situ cis-activation.
Nie, Y., Zhou, L., Wang, H., Chen, N., Jia, L., Wang, C., … Li, W. (2019). Profiling the epigenetic interplay of lncRNA RUNXOR and oncogenic RUNX1 in breast cancer cells by gene in situ cis-activation. American Journal of Cancer Research, 9(8), 1635–49. -
Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective.
Collett-Solberg, P. F., Ambler, G., Backeljauw, P. F., Bidlingmaier, M., Biller, B. M., Boguszewski, M. C., … Woelfle, J. (2019). Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective. Hormone Research in Paediatrics, 1–14. -
Profiling the epigenetic interplay of lncRNA RUNXOR and oncogenic RUNX1 in breast cancer cells by gene in situ cis-activation
Nie, Y., Zhou, L., Wang, H., Chen, N., Jia, L., Wang, C., … Li, W. (2019). Profiling the epigenetic interplay of lncRNA RUNXOR and oncogenic RUNX1 in breast cancer cells by gene in situ cis-activation. AMERICAN JOURNAL OF CANCER RESEARCH, 9(8), 1635-+. -
Effect of MALAT1 in the crosstalk between nucleus and mitochondria on mitochondria! reprogramming in hepatocellular carcinoma cells
Zhao, Y., Cui, J., Hu, J., & Hoffman, A. R. (2019). Effect of MALAT1 in the crosstalk between nucleus and mitochondria on mitochondria! reprogramming in hepatocellular carcinoma cells. JOURNAL OF CLINICAL ONCOLOGY, 37(15). -
Association of change in muscle mass assessed by D3 -creatine dilution with changes in grip strength and walking speed.
Duchowny, K. A., Peters, K. E., Cummings, S. R., Orwoll, E. S., Hoffman, A. R., Ensrud, K. E., … Cawthon, P. M. (2019). Association of change in muscle mass assessed by D3 -creatine dilution with changes in grip strength and walking speed. Journal of Cachexia, Sarcopenia and Muscle. -
Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming.
Du, Z., Jia, L., Wang, Y., Wang, C., Wen, X., Chen, J., … Hu, J.-F. F. (2018). Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming. Scientific Data, 5(1), 180255. -
Genome-wide interaction target profiling reveals a novel Peblr20-eRNA activation pathway to control stem cell pluripotency
Wang, C., Jia, L., Wang, Y., Du, Z., Zhou, L., Wen, X., … Cui, J. (2020). Genome-wide interaction target profiling reveals a novel Peblr20-eRNA activation pathway to control stem cell pluripotency. THERANOSTICS, 10(1), 353–70. -
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO ADULT CARE 2019 AACE GROWTH HORMONE TASK FORCE
Yuen, K. C. J., Biller, B. M. K., Radovick, S., Carmichael, J. D., Jasim, S., Pantalone, K. M., & Hoffman, A. R. (2019). AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO ADULT CARE 2019 AACE GROWTH HORMONE TASK FORCE. ENDOCRINE PRACTICE, 25(11), 1191–1232. -
Genome-wide interaction target profiling reveals a novel Peblr20-eRNA activation pathway to control stem cell pluripotency.
Wang, C., Jia, L., Wang, Y., Du, Z., Zhou, L., Wen, X., … Cui, J. (2020). Genome-wide interaction target profiling reveals a novel Peblr20-eRNA activation pathway to control stem cell pluripotency. Theranostics, 10(1), 353–370. -
Perspectives on long-acting growth hormone therapy in children and adults.
Lal, R. A., & Hoffman, A. R. (2019). Perspectives on long-acting growth hormone therapy in children and adults. Archives of Endocrinology and Metabolism, 63(6), 601–7. -
Oplr16 serves as a novel chromatin factor to control stem cell fate by modulating pluripotency-specific chromosomal looping and TET2-mediated DNA demethylation.
Jia, L., Wang, Y., Wang, C., Du, Z., Zhang, S., Wen, X., … Hu, J.-F. F. (2020). Oplr16 serves as a novel chromatin factor to control stem cell fate by modulating pluripotency-specific chromosomal looping and TET2-mediated DNA demethylation. Nucleic Acids Research. -
Physical Activity Trajectories and Associated Changes in Physical Performance in Older Men: The MrOS Study.
Laddu, D., Parimi, N., Stone, K. L., Lapidus, J., Hoffman, A. R., Stefanick, M., & Langsetmo, L. (2020). Physical Activity Trajectories and Associated Changes in Physical Performance in Older Men: The MrOS Study. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. -
Treatment of the adult growth hormone deficiency syndrome with growth hormone: What are the implications for other hormone replacement therapies for hypopituitarism?
Fierro, G., & Hoffman, A. R. (2020). Treatment of the adult growth hormone deficiency syndrome with growth hormone: What are the implications for other hormone replacement therapies for hypopituitarism? Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 52, 101316. -
Endogenous Testosterone Levels and the Risk of Incident Cardiovascular Events in Elderly Men: The MrOS Prospective Study.
Collet, T.-H., Ewing, S. K., Ensrud, K. E., Laughlin, G. A., Hoffman, A. R., Varosy, P. D., … Bauer, D. C. (2020). Endogenous Testosterone Levels and the Risk of Incident Cardiovascular Events in Elderly Men: The MrOS Prospective Study. Journal of the Endocrine Society, 4(5), bvaa038. -
Osblr8 orchestrates intrachromosomal loop structure required for maintaining stem cell pluripotency
Zhu, Y., Yan, Z., Du, Z., Zhang, S., Fu, C., Meng, Y., … Li, W. (2020). Osblr8 orchestrates intrachromosomal loop structure required for maintaining stem cell pluripotency. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 16(11), 1861–75. -
Individual and joint trajectories of change in bone, lean mass and physical performance in older men.
Cawthon, P. M., Parimi, N., Langsetmo, L., Cauley, J. A., Ensrud, K. E., Cummings, S. R., … Orwoll, E. S. (2020). Individual and joint trajectories of change in bone, lean mass and physical performance in older men. BMC Geriatrics, 20(1), 161. -
Frailty Phenotype and Healthcare Costs and Utilization in Older Men.
Ensrud, K. E., Kats, A. M., Schousboe, J. T., Taylor, B. C., Vo, T. N., Cawthon, P. M., … Langsetmo, L. (2020). Frailty Phenotype and Healthcare Costs and Utilization in Older Men. Journal of the American Geriatrics Society. -
Osblr8 orchestrates intrachromosomal loop structure required for maintaining stem cell pluripotency.
Zhu, Y., Yan, Z., Du, Z., Zhang, S., Fu, C., Meng, Y., … Li, W. (2020). Osblr8 orchestrates intrachromosomal loop structure required for maintaining stem cell pluripotency. International Journal of Biological Sciences, 16(11), 1861–1875. -
Dietary Intake, D3Cr Muscle Mass, and Appendicular Lean Mass in a Cohort of Older Men.
Rogers-Soeder, T. S., Peters, K. E., Lane, N. E., Shikany, J. M., Judd, S., Langsetmo, L., … Cawthon, P. M. (2020). Dietary Intake, D3Cr Muscle Mass, and Appendicular Lean Mass in a Cohort of Older Men. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 75(7), 1353–61. -
Height Loss in Old Age and Hip Fracture Risk Among Men in Late Life: Findings from the Osteoporotic Fractures in Men (MrOS) Study
Ensrud, K., Schousboe, J., Kats, A., Tien Vo, Taylor, B., Cawthon, P., … Langsetmo, L. (2020). Height Loss in Old Age and Hip Fracture Risk Among Men in Late Life: Findings from the Osteoporotic Fractures in Men (MrOS) Study. JOURNAL OF BONE AND MINERAL RESEARCH, 35, 215. -
Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway.
Zhao, Y., Zhou, L., Li, H., Sun, T., Wen, X., Li, X., … Cui, J. (2021). Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway. Molecular Therapy. Nucleic Acids, 23, 264–76. -
Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time?
Ho, K., Fleseriu, M., Kaiser, U., Salvatori, R., Brue, T., Lopes, M. B., … Melmed, S. (2021). Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time? Journal of the Endocrine Society, 5(3), bvaa205. -
Height Loss in Old Age and Fracture Risk Among Men in Late Life: A Prospective Cohort Study.
Ensrud, K. E., Schousboe, J. T., Kats, A. M., Vo, T. N., Taylor, B. C., Cawthon, P. M., … Langsetmo, L. (2021). Height Loss in Old Age and Fracture Risk Among Men in Late Life: A Prospective Cohort Study. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. -
Usefulness and Potential Pitfalls of Long-Acting Growth Hormone Analogs.
Yuen, K. C., Miller, B. S., Boguszewski, C. L., & Hoffman, A. R. (2021). Usefulness and Potential Pitfalls of Long-Acting Growth Hormone Analogs. Frontiers in Endocrinology, 12, 637209. -
Corrigendum: Usefulness and Potential Pitfalls of Long-Acting Growth Hormone Analogues.
Yuen, K. C., Miller, B. S., Boguszewski, C. L., & Hoffman, A. R. (2021). Corrigendum: Usefulness and Potential Pitfalls of Long-Acting Growth Hormone Analogues. Frontiers in Endocrinology, 12, 705241. -
Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men.
Fu, L., Yuen, K. C., Tint, A. N., Hoffman, A. R., Bongso, A. T., & Lee, K. O. (2021). Association of decreased sperm motility and increased seminal plasma IGF-I, IGF-II, IGFBP-2, and PSA levels in infertile men. Endocrine. -
Chromatin lncRNA Platr10 controls stem cell pluripotency by coordinating an intrachromosomal regulatory network.
Du, Z., Wen, X., Wang, Y., Jia, L., Zhang, S., Liu, Y., … Hu, J.-F. (2021). Chromatin lncRNA Platr10 controls stem cell pluripotency by coordinating an intrachromosomal regulatory network. Genome Biology, 22(1), 233. -
CT muscle density, D3Cr muscle mass and body fat associations with physical performance, mobility outcomes and mortality risk in older men.
Orwoll, E., Blackwell, T., Cummings, S. R., Cauley, J. A., Lane, N. E., Hoffman, A. R., … Cawthon, P. M. (2021). CT muscle density, D3Cr muscle mass and body fat associations with physical performance, mobility outcomes and mortality risk in older men. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. -
Author Correction: Chromatin lncRNA Platr10 controls stem cell pluripotency by coordinating an intrachromosomal regulatory network.
Du, Z., Wen, X., Wang, Y., Jia, L., Zhang, S., Liu, Y., … Hu, J.-F. (2021). Author Correction: Chromatin lncRNA Platr10 controls stem cell pluripotency by coordinating an intrachromosomal regulatory network. Genome Biology, 22(1), 272. -
The Nucleus/Mitochondria-Shuttling LncRNAs Function as New Epigenetic Regulators of Mitophagy in Cancer
Li, Y., Li, W., Hoffman, A. R., Cui, J., & Hu, J.-F. (2021). The Nucleus/Mitochondria-Shuttling LncRNAs Function as New Epigenetic Regulators of Mitophagy in Cancer. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9, 699621. -
Lower urinary tract symptoms and incident functional limitations among older community-dwelling men.
Bauer, S. R., Cawthon, P. M., Ensrud, K. E., Suskind, A. M., Newman, J. C., Fink, H. A., … Marshall, L. M. (1800). Lower urinary tract symptoms and incident functional limitations among older community-dwelling men. Journal of the American Geriatrics Society. -
Corrigendum to: CT Muscle Density, D3Cr Muscle Mass, and Body Fat Associations With Physical Performance, Mobility Outcomes, and Mortality Risk in Older Men.
Orwoll, E. S., Blackwell, T., Cummings, S. R., Cauley, J. A., Lane, N. E., Hoffman, A. R., … Cawthon, P. M. (1800). Corrigendum to: CT Muscle Density, D3Cr Muscle Mass, and Body Fat Associations With Physical Performance, Mobility Outcomes, and Mortality Risk in Older Men. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. -
Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture.
Wang, Y., Jia, L., Wang, C., Du, Z., Zhang, S., Zhou, L., … Hu, J.-F. F. (2022). Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture. The Journal of Cell Biology, 221(4). -
Hearing Dysfunction After Treatment with Teprotumumab for Thyroid Eye Disease.
Sears, C. M., Azad, A. D., Amarikwa, L., Pham, B. H., Men, C. J., Kaplan, D. N., … Kossler, A. L. (2022). Hearing Dysfunction After Treatment with Teprotumumab for Thyroid Eye Disease. American Journal of Ophthalmology. -
Association Between Muscle Mass Determined by D3 -Creatine Dilution and Incident Fractures in a Prospective Cohort Study of Older Men.
Cawthon, P. M., Peters, K. E., Cummings, S. R., Orwoll, E. S., Hoffman, A. R., Ensrud, K. E., … Evans, W. J. (2022). Association Between Muscle Mass Determined by D3 -Creatine Dilution and Incident Fractures in a Prospective Cohort Study of Older Men. Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. -
Safety of growth hormone replacement in survivors of cancer and intra-cranial and pituitary tumours - A consensus statement.
Boguszewski, M. C., Boguszewski, C. L., Chemaitilly, W., Cohen, L. E., Gebauer, J., Higham, C., … Johannsson, G. (2022). Safety of growth hormone replacement in survivors of cancer and intra-cranial and pituitary tumours - A consensus statement. European Journal of Endocrinology. -
Adult Growth Hormone Deficiency: Diagnostic and Treatment Journeys From the Patients' Perspective.
Hoffman, A. R., Mathison, T., Andrews, D., Murray, K., Kelepouris, N., & Fleseriu, M. (2022). Adult Growth Hormone Deficiency: Diagnostic and Treatment Journeys From the Patients' Perspective. Journal of the Endocrine Society, 6(7), bvac077. -
Prospective intraoperative and histologic evaluation of cavernous sinus medial wall invasion by pituitary adenomas and its implications for acromegaly remission outcomes.
Mohyeldin, A., Katznelson, L. J., Hoffman, A. R., Asmaro, K., Ahmadian, S. S., Eltobgy, M. M., … Fernandez-Miranda, J. C. (2022). Prospective intraoperative and histologic evaluation of cavernous sinus medial wall invasion by pituitary adenomas and its implications for acromegaly remission outcomes. Scientific Reports, 12(1), 9919. -
Development of a Novel Algorithm to Identify People with High Likelihood of Adult Growth Hormone Deficiency in a US Healthcare Claims Database.
Yuen, K. C., Birkegard, A. C., Blevins, L. S., Clemmons, D. R., Hoffman, A. R., Kelepouris, N., … Fleseriu, M. (2022). Development of a Novel Algorithm to Identify People with High Likelihood of Adult Growth Hormone Deficiency in a US Healthcare Claims Database. International Journal of Endocrinology, 2022, 7853786. -
A consensus on optimization of care in patients with growth hormone deficiency and mild traumatic brain injury.
Yuen, K. C., Masel, B., Jaffee, M. S., O'Shanick, G., Wexler, T. L., Reifschneider, K., … Hoffman, A. R. (2022). A consensus on optimization of care in patients with growth hormone deficiency and mild traumatic brain injury. Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society, 66, 101495. -
HULC targets the IGF1R-PI3K-AKT axis in trans to promote breast cancer metastasis and cisplatin resistance.
Zhou, L., Li, H., Sun, T., Wen, X., Niu, C., Li, M., … Cui, J. (2022). HULC targets the IGF1R-PI3K-AKT axis in trans to promote breast cancer metastasis and cisplatin resistance. Cancer Letters, 215861. -
Intrachromosomal Looping and Histone K27 Methylation Coordinately Regulates the lncRNA H19-Fetal Mitogen IGF2 Imprinting Cluster in the Decidual Microenvironment of Early Pregnancy.
Wen, X., Zhang, Q., Zhou, L., Li, Z., Wei, X., Yang, W., … Cui, J. (2022). Intrachromosomal Looping and Histone K27 Methylation Coordinately Regulates the lncRNA H19-Fetal Mitogen IGF2 Imprinting Cluster in the Decidual Microenvironment of Early Pregnancy. Cells, 11(19). -
Tracking and Cumulative Lifetime Exposure to IGF-I in 6,459 Healthy Individuals and in SGA Children Treated with GH.
Kjaer, A. S., Jensen, R. B., Petersen, J. H., Linneberg, A., Karhus, L. L., Henriksen, L. S., … Juul, A. (2022). Tracking and Cumulative Lifetime Exposure to IGF-I in 6,459 Healthy Individuals and in SGA Children Treated with GH. The Journal of Clinical Endocrinology and Metabolism. -
LncRNA Osilr9 coordinates promoter DNA demethylation and the intrachromosomal loop structure required for maintaining stem cell pluripotency.
Zhu, Y., Yan, Z., Fu, C., Wen, X., Jia, L., Zhou, L., … Li, W. (2022). LncRNA Osilr9 coordinates promoter DNA demethylation and the intrachromosomal loop structure required for maintaining stem cell pluripotency. Molecular Therapy : the Journal of the American Society of Gene Therapy. -
Eukaryotic translation initiation factor eIF4G2 opens novel paths for protein synthesis in development, apoptosis and cell differentiation.
Liu, Y., Cui, J., Hoffman, A. R., & Hu, J.-F. (2022). Eukaryotic translation initiation factor eIF4G2 opens novel paths for protein synthesis in development, apoptosis and cell differentiation. Cell Proliferation, e13367. -
Growth Hormone Deficiency Following Traumatic Brain Injury in Pediatric and Adolescent Patients: Presentation, Treatment, and Challenges of Transitioning From Pediatric to Adult Services.
Wexler, T., Reifschneider, K., Backeljauw, P., Cardenas, J. F., Hoffman, A. R., Miller, B. S., & Yuen, K. C. (2023). Growth Hormone Deficiency Following Traumatic Brain Injury in Pediatric and Adolescent Patients: Presentation, Treatment, and Challenges of Transitioning From Pediatric to Adult Services. Journal of Neurotrauma. -
Development of a minimum data set for the monitoring of recombinant human growth hormone (rhGH) therapy in children with growth hormone deficiency (GHD)- a globe-reg initiative
Chen, S. C., Charmandari, E., Choi, J.-H., Dou, X., Gong, C., Hamza, R., … Ahmed, S. F. (2023). Development of a minimum data set for the monitoring of recombinant human growth hormone (rhGH) therapy in children with growth hormone deficiency (GHD)- a globe-reg initiative. HORMONE RESEARCH IN PAEDIATRICS. KARGER. -
CAN MUSCLE MASS EXPLAIN THE RELATIONSHIP BETWEEN EGFRDIFF (=EGFRCYSEGFRCR) AND FRAILTY IN OLDER MEN?
Yuan, J. H., Rifkin, D. E., Ginsberg, C., Cawthon, P., Kado, D. M., Bauer, S. R., … Potok, O. A. (2023). CAN MUSCLE MASS EXPLAIN THE RELATIONSHIP BETWEEN EGFRDIFF (=EGFRCYSEGFRCR) AND FRAILTY IN OLDER MEN? AMERICAN JOURNAL OF KIDNEY DISEASES. W B SAUNDERS CO-ELSEVIER INC. -
Chromatin-RNA in situ Reverse Transcription Sequencing (CRIST-seq) Approach to Profile the Non-coding RNA Interaction Network.
Zhang, S., Wen, X., Zhou, L., Li, H., Li, W., Hoffman, A. R., … Cui, J. (2023). Chromatin-RNA in situ Reverse Transcription Sequencing (CRIST-seq) Approach to Profile the Non-coding RNA Interaction Network. Bio-Protocol, 13(14), e4718. -
Development of A Minimum Dataset for the Monitoring of Recombinant Human Growth Hormone (rhGH) Therapy Use in Children with Growth Hormone Deficiency (GHD) - A GloBE-Reg Initiative
Chen, S. C., Bryce, J., Chen, M., Charmandari, E., Choi, J.-H., Dou, X., … Ahmed, S. F. (2023). Development of A Minimum Dataset for the Monitoring of Recombinant Human Growth Hormone (rhGH) Therapy Use in Children with Growth Hormone Deficiency (GHD) - A GloBE-Reg Initiative. HORMONE RESEARCH IN PAEDIATRICS. -
Erratum: Genome-wide target interactome profiling reveals a novelEEF1A1epigenetic pathway for oncogenic lncRNAMALAT1in breast cancer.
Li, X., Chen, N., Zhou, L., Wang, C., Wen, X., Jia, L., … Li, W. (2023). Erratum: Genome-wide target interactome profiling reveals a novelEEF1A1epigenetic pathway for oncogenic lncRNAMALAT1in breast cancer. American Journal of Cancer Research, 13(9), 4490–4491. -
Development of A Minimum Data Set for A Growth Hormone Module For Pediatric Growth Hormone Deficiency In The Global Registry For Novel Therapies In Rare Bone & Endocrine Conditions - The GloBE-Reg GH Study
Miller, B. S., Chen, S. C., Charmandari, E., Choi, J. H., Dou, X., Gong, C., … Ahmed, S. F. (2023). Development of A Minimum Data Set for A Growth Hormone Module For Pediatric Growth Hormone Deficiency In The Global Registry For Novel Therapies In Rare Bone & Endocrine Conditions - The GloBE-Reg GH Study. HORMONE RESEARCH IN PAEDIATRICS. KARGER. -
Profiling mitochondria-polyribosome lncRNAs associated with pluripotency.
Zhou, L., Li, H., Sun, T., Wen, X., Niu, C., Li, M., … Cui, J. (2023). Profiling mitochondria-polyribosome lncRNAs associated with pluripotency. Scientific Data, 10(1), 755. -
A systematic review of core outcomes reported in clinical trials of growth hormone therapy in children with growth hormone deficiency
Tseretopoulou, X., Lucas-Herald, A., Chen, J., Bachega, T., Charmandari, E., Choi, J.-H., … Ahmed, S. F. (2023). A systematic review of core outcomes reported in clinical trials of growth hormone therapy in children with growth hormone deficiency. HORMONE RESEARCH IN PAEDIATRICS. KARGER.
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Palo Alto, CAStanford Neuroscience Health Center
213 Quarry Road
Palo Alto , CA 94304
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