Antonio Hardan, M.D.

Psychiatrist

Professional Education

Internship: St Elizabeth Hospital (1991) DC

Medical Education: St Joseph's University (1988) Lebanon

Board Certification: Child and Adolescent Psychiatry, American Board of Psychiatry and Neurology (1997)

Fellowship: University of Pittsburgh (1996) PA

Board Certification: Psychiatry, American Board of Psychiatry and Neurology (1995)

Residency: Strong Memorial Hospital (1993) NY

Administrative Appointments

Acting Director, Division of Child and Adolescent Psychiatry, 2013

Medical Director, Outpatient Program, Division of Child and Adolescent Psychiatry, 2011

Director, Autism and Developmental Disabilities Clinic, 2006

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Emotion dysregulation and the core features of autism spectrum disorder.
Samson, A. C., Phillips, J. M., Parker, K. J., Shah, S., Gross, J. J., & Hardan, A. Y. (2014). Emotion dysregulation and the core features of autism spectrum disorder. Journal of autism and developmental disorders, 44(7), 1766-1772.

Behavioral and cognitive characteristics of females and males with autism in the simons simplex collection.
Frazier, T. W., Georgiades, S., Bishop, S. L., & Hardan, A. Y. (2014). Behavioral and cognitive characteristics of females and males with autism in the simons simplex collection. Journal of the American Academy of Child and Adolescent Psychiatry, 53(3), 329-340 e3.

A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism
Barnea-Goraly, N., Frazier, T. W., Piacenza, L., Minshew, N. J., Keshavan, M. S., & Hardan, A. Y. (2014). A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 48, 124-128.

A scoring strategy combining statistics and functional genomics supports a possible role for common polygenic variation in autism.
Carayol, J., Schellenberg, G. D., Dombroski, B., Amiet, C., Génin, B., & Rio Frio, T. (2014). A scoring strategy combining statistics and functional genomics supports a possible role for common polygenic variation in autism. Frontiers in genetics, 5, 33-?.

A Twin Study of Heritable and Shared Environmental Contributions to Autism.
Frazier, T. W., Thompson, L., Youngstrom, E. A., Law, P., Hardan, A. Y., & Morris, N. (2014). A Twin Study of Heritable and Shared Environmental Contributions to Autism. Journal of autism and developmental disorders.

A two-year longitudinal pilot MRI study of the brainstem in autism.
Jou, R. J., Frazier, T. W., Keshavan, M. S., Minshew, N. J., & Hardan, A. Y. (2013). A two-year longitudinal pilot MRI study of the brainstem in autism. Behavioural brain research, 251, 163-167.

Impact of Pivotal Response Training Group Therapy on Stress and Empowerment in Parents of Children With Autism
Minjarez, M. B., Mercier, E. M., Williams, S. E., & Hardan, A. Y. (2013). Impact of Pivotal Response Training Group Therapy on Stress and Empowerment in Parents of Children With Autism. JOURNAL OF POSITIVE BEHAVIOR INTERVENTIONS, 15(2), 71-78.

Parental Interest in a Genetic Risk Assessment Test for Autism Spectrum Disorders
Narcisa, V., Discenza, M., Vaccari, E., Rosen-Sheidley, B., Hardan, A. Y., & Couchon, E. (2013). Parental Interest in a Genetic Risk Assessment Test for Autism Spectrum Disorders. CLINICAL PEDIATRICS, 52(2), 139-146.

Demographic and clinical correlates of autism symptom domains and autism spectrum diagnosis
Frazier, Tw., Youngstrom, Ea., Embacher, R., Hardan, Ay., Constantino, Jn., & Eng, C. (2013). Demographic and clinical correlates of autism symptom domains and autism spectrum diagnosis. Autism.

Priapism Associated with Risperidone in a 21-Year-Old Male with Autism.
Pradhan, T., & Hardan, A. (2013). Priapism Associated with Risperidone in a 21-Year-Old Male with Autism. Journal of child and adolescent psychopharmacology.

Underutilization of Genetics Services for Autism: The Importance of Parental Awareness and Provider Recommendation
Vande Wydeven, K., Kwan, A., Hardan, A. Y., & Bernstein, J. A. (2012). Underutilization of Genetics Services for Autism: The Importance of Parental Awareness and Provider Recommendation. JOURNAL OF GENETIC COUNSELING, 21(6), 803-813.

Clinical practice pathways for evaluation and medication choice for attention-deficit/hyperactivity disorder symptoms in autism spectrum disorders.
Mahajan, R., Bernal, M. P., Panzer, R., Whitaker, A., Roberts, W., & Veenstra-VanderWeele, J. (2012). Clinical practice pathways for evaluation and medication choice for attention-deficit/hyperactivity disorder symptoms in autism spectrum disorders. Pediatrics, 130, S125-38.

A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism
Frazier, T. W., Keshavan, M. S., Minshew, N. J., & Hardan, A. Y. (2012). A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 42(11), 2312-2322.

A Retrospective Review of the Effectiveness of Aripiprazole in the Treatment of Sensory Abnormalities in Autism
Fung, L. K., Chahal, L., Libove, R. A., Bivas, R., & Hardan, A. Y. (2012). A Retrospective Review of the Effectiveness of Aripiprazole in the Treatment of Sensory Abnormalities in Autism. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 22(3), 245-248.

A Randomized Controlled Pilot Trial of Oral N-Acetylcysteine in Children with Autism
Hardan, A. Y., Fung, L. K., Libove, R. A., Obukhanych, T. V., Nair, S., & Tirouvanziam, R. (2012). A Randomized Controlled Pilot Trial of Oral N-Acetylcysteine in Children with Autism. BIOLOGICAL PSYCHIATRY, 71(11), 956-961.

Distinct Plasma Profile of Polar Neutral Amino Acids, Leucine, and Glutamate in Children with Autism Spectrum Disorders
Tirouvanziam, R., Obukhanych, T. V., Laval, J., Aronov, P. A., Libove, R., & Hardan, A. Y. (2012). Distinct Plasma Profile of Polar Neutral Amino Acids, Leucine, and Glutamate in Children with Autism Spectrum Disorders. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 42(5), 827-836.

Validation of Proposed DSM-5 Criteria for Autism Spectrum Disorder
Frazier, T. W., Youngstrom, E. A., Speer, L., Embacher, R., Law, P., & Eng, C. (2012). Validation of Proposed DSM-5 Criteria for Autism Spectrum Disorder. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 51(1), 28-40.

Advances in clinical neuroimaging: implications for autism spectrum disorders.
Barnea-Goraly, N., & Hardan, A. (2011). Advances in clinical neuroimaging: implications for autism spectrum disorders. Expert opinion on medical diagnostics, 5(6), 475-482.

Multivariate Searchlight Classification of Structural Magnetic Resonance Imaging in Children and Adolescents with Autism
Uddin, L. Q., Menon, V., Young, C. B., Ryali, S., Chen, T., & Hardan, A. Y. (2011). Multivariate Searchlight Classification of Structural Magnetic Resonance Imaging in Children and Adolescents with Autism. BIOLOGICAL PSYCHIATRY, 70(9), 833-841.

Safety and Efficacy of Donepezil in Children and Adolescents with Autism: Neuropsychological Measures
Handen, B. L., Johnson, C. R., McAuliffe-Bellin, S., Murray, P. J., & Hardan, A. Y. (2011). Safety and Efficacy of Donepezil in Children and Adolescents with Autism: Neuropsychological Measures. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 21(1), 43-50.

Reduced central white matter volume in autism: Implications for long-range connectivity
Jou, R. J., Mateljevic, N., Minshew, N. J., Keshavan, M. S., & Hardan, A. Y. (2011). Reduced central white matter volume in autism: Implications for long-range connectivity. PSYCHIATRY AND CLINICAL NEUROSCIENCES, 65(1), 98-101.

Pivotal Response Group Treatment Program for Parents of Children with Autism
Minjarez, M. B., Williams, S. E., Mercier, E. M., & Hardan, A. Y. (2011). Pivotal Response Group Treatment Program for Parents of Children with Autism. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 41(1), 92-101.

Cortical Gyrification in Autistic and Asperger Disorders: A Preliminary Magnetic Resonance Imaging Study
Jou, R. J., Minshew, N. J., Keshavan, M. S., & Hardan, A. Y. (2010). Cortical Gyrification in Autistic and Asperger Disorders: A Preliminary Magnetic Resonance Imaging Study. JOURNAL OF CHILD NEUROLOGY, 25(12), 1462-1467.

Enlarged right superior temporal gyrus in children and adolescents with autism
Jou, R. J., Minshew, N. J., Keshavan, M. S., Vitale, M. P., & Hardan, A. Y. (2010). Enlarged right superior temporal gyrus in children and adolescents with autism. BRAIN RESEARCH, 1360, 205-212.

Risperidone: Switching from Brand Name to Generic
Hardan, A. Y., Fung, L. K., & Amin, H. (2010). Risperidone: Switching from Brand Name to Generic. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 20(5), 457-458.

Dorsolateral Prefrontal Cortex Magnetic Resonance Imaging Measurements and Cognitive Performance in Autism
Griebling, J., Minshew, N. J., Bodner, K., Libove, R., Bansal, R., & Hardan, A. (2010). Dorsolateral Prefrontal Cortex Magnetic Resonance Imaging Measurements and Cognitive Performance in Autism. JOURNAL OF CHILD NEUROLOGY, 25(7), 856-863.

Evidence for Anatomical Alterations in the Corpus Callosum in Autism Spectrum Disorders
Frazier T, Barnea-Goraly N, & Hardan A. (2010). Evidence for Anatomical Alterations in the Corpus Callosum in Autism Spectrum Disorders. European Psychiatric Review, 3.

A Meta-Analysis of the Corpus Callosum in Autism
Frazier, T. W., & Hardan, A. Y. (2009). A Meta-Analysis of the Corpus Callosum in Autism. BIOLOGICAL PSYCHIATRY, 66(10), 935-941.

Corpus callosum volume in children with autism
Hardan, A. Y., Pabalan, M., Gupta, N., Bansal, R., Melhem, N. M., & Minshew, N. J. (2009). Corpus callosum volume in children with autism. PSYCHIATRY RESEARCH-NEUROIMAGING, 174(1), 57-61.

A Preliminary Longitudinal Magnetic Resonance Imaging Study of Brain Volume and Cortical Thickness in Autism
Hardan, A. Y., Libove, R. A., Keshavan, M. S., Melhem, N. M., & Minshew, N. J. (2009). A Preliminary Longitudinal Magnetic Resonance Imaging Study of Brain Volume and Cortical Thickness in Autism. BIOLOGICAL PSYCHIATRY, 66(4), 320-326.

Brainstem volumetric alterations in children with autism
Jou, R. J., Minshew, N. J., Melhem, N. M., Keshavan, M. S., & Hardan, A. Y. (2009). Brainstem volumetric alterations in children with autism. PSYCHOLOGICAL MEDICINE, 39(8), 1347-1354.

Corpus Callosum Volume and Neurocognition in Autism
Keary, C. J., Minshew, N. J., Bansal, R., Goradia, D., Fedorov, S., & Hardan, A. Y. (2009). Corpus Callosum Volume and Neurocognition in Autism. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 39(6), 834-841.

Guanfacine in children with autism and/or intellectual disabilities
Handen, B. L., Sahl, R., & Hardan, A. Y. (2008). Guanfacine in children with autism and/or intellectual disabilities. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 29(4), 303-308.

An MRI and proton spectroscopy study of the thalamus in children with autism
Hardan, A. Y., Minshew, N. J., Melhem, N. M., Srihari, S., Jo, B., & Stanley, J. A. (2008). An MRI and proton spectroscopy study of the thalamus in children with autism. PSYCHIATRY RESEARCH-NEUROIMAGING, 163(2), 97-105.

Brief report: Abnormal association between the thalamus and brain size in Asperger's disorder
Hardan, A. Y., GirgiS, R. R., Adams, J., Gilbert, A. R., Melhem, N. M., & Minshew, N. J. (2008). Brief report: Abnormal association between the thalamus and brain size in Asperger's disorder. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 38(2), 390-394.

Morphology of the orbitofrontal cortex in first-episode schizophrenia: Relationship with negative symptomatology
Lacerda, A. Lt., Hardan, A. Y., Yorbik, O., Vemulapalli, M., Prasad, K. M., & Keshavan, M. S. (2007). Morphology of the orbitofrontal cortex in first-episode schizophrenia: Relationship with negative symptomatology. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 31(2), 510-516.

Volumetric alterations of the orbitofrontal cortex in autism
GirgiS, R. R., Minshew, N. J., Melhern, N. M., Nutche, J. J., Keshavan, M. S., & Hardan, A. Y. (2007). Volumetric alterations of the orbitofrontal cortex in autism. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 31(1), 41-45.

Abnormal brain size effect on the thalamus in autism
Hardan, A. Y., GirgiS, R. R., Adams, J., Gilbert, A. R., Keshavan, M. S., & Minshew, N. J. (2006). Abnormal brain size effect on the thalamus in autism. PSYCHIATRY RESEARCH-NEUROIMAGING, 147(2-3), 145-151.

Magnetic resonance imaging study of the orbitofrontal cortex in autism
Hardan, A. Y., GirgiS, R. R., Lacerda, A. Lt., Yorbik, O., Kilpatiick, M., & Minshew, N. J. (2006). Magnetic resonance imaging study of the orbitofrontal cortex in autism. JOURNAL OF CHILD NEUROLOGY, 21(10), 866-871.

Open-label, prospective trial of olanzapine in adolescents with subaverage intelligence and disruptive behavior disorders
Handen, B. L., & Hardan, A. Y. (2006). Open-label, prospective trial of olanzapine in adolescents with subaverage intelligence and disruptive behavior disorders. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 45(8), 928-935.

An MRI study of increased cortical thickness in autism
Hardan, A. Y., Muddasani, S., Vemulapalli, M., Keshavan, M. S., & Minshew, N. J. (2006). An MRI study of increased cortical thickness in autism. AMERICAN JOURNAL OF PSYCHIATRY, 163(7), 1290-1292.

An MRI study of minor physical anomalies in autism
Hardan, A. Y., Keshavan, M. S., Sreedhar, S., Vemulapalli, M., & Minshew, N. J. (2006). An MRI study of minor physical anomalies in autism. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 36(5), 607-611.

Risperidone in first-episode psychosis: A longitudinal, exploratory voxel-based morphometric study
Girgis, R. R., Diwadkar, V. A., Nutche, J. J., Sweeney, J. A., Keshavan, M. S., & Hardan, A. Y. (2006). Risperidone in first-episode psychosis: A longitudinal, exploratory voxel-based morphometric study. SCHIZOPHRENIA RESEARCH, 82(1), 89-94.

Reduced cortical folding in individuals at high risk for schizophrenia: a pilot study
Jou, R. J., Hardan, A. Y., & Keshavan, M. S. (2005). Reduced cortical folding in individuals at high risk for schizophrenia: a pilot study. SCHIZOPHRENIA RESEARCH, 75(2-3), 309-313.

Retrospective study of quetiapine in children and adolescents with pervasive developmental disorders
Hardan, A. Y., Jou, R. J., & Handen, B. L. (2005). Retrospective study of quetiapine in children and adolescents with pervasive developmental disorders. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 35(3), 387-391.

Retrospective assessment of atomoxetine in children and adolescents with pervasive developmental disorders
Jou, R. J., Handen, B. L., & Hardan, A. Y. (2005). Retrospective assessment of atomoxetine in children and adolescents with pervasive developmental disorders. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 15(2), 325-330.

Quetiapine in children and adolescents with subaverage IQ
Jou R, Handen BL, & Hardan AY. (2005). Quetiapine in children and adolescents with subaverage IQ. Journal of Pediatric Neurology, 3.

Psychostimulant treatment of adults with mental retardation and attention-deficit hyperactivity disorder.
Jou, R., Handen, B., & Hardan, A. (2004). Psychostimulant treatment of adults with mental retardation and attention-deficit hyperactivity disorder. Australasian psychiatry , 12(4), 376-379.

A retrospective assessment of topiramate in children and adolescents with pervasive developmental disorders
Hardan, A. Y., Jou, R. J., & Handen, B. L. (2004). A retrospective assessment of topiramate in children and adolescents with pervasive developmental disorders. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 14(3), 426-432.

Increased frontal cortical folding in autism: a preliminary MRI study
Hardan, A. Y., Jou, R. J., Keshavan, M. S., Varma, R., & Minshew, N. J. (2004). Increased frontal cortical folding in autism: a preliminary MRI study. PSYCHIATRY RESEARCH-NEUROIMAGING, 131(3), 263-268.

Neuropsychiatric problems in tuberous sclerosis complex
Asato, M. R., & Hardan, A. Y. (2004). Neuropsychiatric problems in tuberous sclerosis complex. JOURNAL OF CHILD NEUROLOGY, 19(4), 241-249.

Anatomic evaluation of the orbitofrontal cortex in major depressive disorder
Lacerda, A. Lt., Keshavan, M. S., Hardan, A. Y., Yorbik, O., Brambilla, P., & Soares, J. C. (2004). Anatomic evaluation of the orbitofrontal cortex in major depressive disorder. BIOLOGICAL PSYCHIATRY, 55(4), 353-358.

The functional neuroanatomy of autism
Brambilla, P., Hardan, A. Y., di Nemi, S. U., Caverzasi, E., Soares, J. C., & Barale, F. (2004). The functional neuroanatomy of autism. FUNCTIONAL NEUROLOGY, 19(1), 9-17.

Brain anatomy and development in autism: review of structural MRI studies
Brambilla, P., Hardan, A., di Nemi, S. U., Perez, J., Soares, J. C., & Barale, F. (2003). Brain anatomy and development in autism: review of structural MRI studies. BRAIN RESEARCH BULLETIN, 61(6), 557-569.

Measurement of the orbitofrontal cortex: a validation study of a new method
Lacerda, A. Lt., Hardan, A. Y., Yorbik, O., & Keshavan, M. S. (2003). Measurement of the orbitofrontal cortex: a validation study of a new method. NEUROIMAGE, 19(3), 665-673.

Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autism
Hardan, A. Y., Kilpatrick, M., Keshavan, M. S., & Minshew, N. J. (2003). Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autism. JOURNAL OF CHILD NEUROLOGY, 18(5), 317-324.

A retrospective open trial of adjunctive donepezil in children and adolescents with autistic disorder
Hardan, A. Y., & Handen, B. L. (2002). A retrospective open trial of adjunctive donepezil in children and adolescents with autistic disorder. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 12(3), 237-241.

Posterior fossa magnetic resonance imaging in autism
Hardan, A. Y., Minshew, N. J., Harenski, K., & Keshavan, M. S. (2001). Posterior fossa magnetic resonance imaging in autism. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 40(6), 666-672.

Brain volume in autism
Hardan, A. Y., Minshew, N. J., Mallikarjuhn, M., & Keshavan, M. S. (2001). Brain volume in autism. JOURNAL OF CHILD NEUROLOGY, 16(6), 421-424.

Corpus callosum size in autism
Hardan, A. Y., Minshew, N. J., & Keshavan, M. S. (2000). Corpus callosum size in autism. NEUROLOGY, 55(7), 1033-1036.

Inositol as an add-on treatment for bipolar depression
Chengappa, K. Nr., Levine, J., Gershon, S., Mallinger, A. G., Hardan, A., & Kupfer, D. J. (2000). Inositol as an add-on treatment for bipolar depression. BIPOLAR DISORDERS, 2(1), 47-55.

Prolactin secretion in depressed children
Hardan, A., Birmaher, B., Williamson, D. E., Dahl, R. E., Ambrosini, P., & Ryan, N. D. (1999). Prolactin secretion in depressed children. BIOLOGICAL PSYCHIATRY, 46(4), 506-511.

Suicidal behavior in children and adolescents with developmental disorders
Hardan, A., & SAHL, R. (1999). Suicidal behavior in children and adolescents with developmental disorders. RESEARCH IN DEVELOPMENTAL DISABILITIES, 20(4), 287-296.

Psychopathology in children and adolescents with developmental disorders
Hardan, A., & SAHL, R. (1997). Psychopathology in children and adolescents with developmental disorders. RESEARCH IN DEVELOPMENTAL DISABILITIES, 18(5), 369-382.

Risperidone treatment of children and adolescents with developmental disorders
Hardan, A., Johnson, K., Johnson, C., & HRECZNYJ, B. (1996). Risperidone treatment of children and adolescents with developmental disorders. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 35(11), 1551-1556.