Dora Ho

Infectious disease doctor

Clinical Associate Professor, Medicine - Infectious Diseases

Heart Transplant Program

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-5468
Learn More About the Clinic Getting Here Make An Appointment

Infectious Disease Clinic

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-736-5200
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Residency: Santa Clara Valley Medical Center (2003) CA

Medical Education: Washington University in St Louis (2001) MO

Board Certification: Infectious Disease, American Board of Internal Medicine (2005)

Fellowship: Stanford University Medical Center (2005) CA

Board Certification: Internal Medicine, American Board of Internal Medicine (2004)

MD, Washington University, St. Louis (2001)

PhD, Stanford University, Herpesvirology (1990)

BA, UC San Diego, Microbiology (1984)

Honors & Awards

Postdoctoral Fellowship, Huntington’s Disease Society of America (1991-1993)

Morris Alex, M.D. Prize for clinical medicine, Washington University School of Medicine (1999)

Dr. Lee B. & Virginia G. Harrison Scholarship for internal medicine, Washington University School of Medicine (1999 & 2000)

Gene transfer using herpes virus vectors as a tool for neuroprotection, US Patent No: 5661033 (1997)

Administrative Appointments

Chair, Antibiotic Subcommittee (2009 - Present)

Clinical Chief, Div of Infectious Diseases (2010 - Present)

Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults.
Creech, C. B., Dekker, C. L., Ho, D., Phillips, S., Mackey, S., & Edwards, K. M. (2013). Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults. Human vaccines & immunotherapeutics, 9(12), 2548-2557.

Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults
Creech, C. B., Dekker, C. L., Ho, D., Phillips, S., Mackey, S., & Edwards, K. M. (2013). Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 9(12), 2548-2557.

Utility of DNA Sequencing for Direct Identification of Invasive Fungi From Fresh and Formalin-Fixed Specimens
Moncada, P. A., Budvytiene, I., Ho, D. Y., Deresinski, S. C., Montoya, J. G., & Banaei, N. (2013). Utility of DNA Sequencing for Direct Identification of Invasive Fungi From Fresh and Formalin-Fixed Specimens. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 140(2), 203-208.

Clinical Significance of Low Cytomegalovirus DNA Levels in Human Plasma
Waggoner, J., Ho, D. Y., Libiran, P., & Pinsky, B. A. (2012). Clinical Significance of Low Cytomegalovirus DNA Levels in Human Plasma. JOURNAL OF CLINICAL MICROBIOLOGY, 50(7), 2378-2383.

Early CMV Viremia Is Associated with Impaired Viral Control following Nonmyeloablative Hematopoietic Cell Transplantation with a Total Lymphoid Irradiation and Antithymocyte Globulin Preparative Regimen
Schaenman, J. M., Shashidhar, S., Rhee, C., Wong, J., Navato, S., & Brown, J. M. (2011). Early CMV Viremia Is Associated with Impaired Viral Control following Nonmyeloablative Hematopoietic Cell Transplantation with a Total Lymphoid Irradiation and Antithymocyte Globulin Preparative Regimen. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 17(5), 693-702.

Brain Abscess Caused by Phaeoacremonium parasiticum in an Immunocompromised Patient
McNeil, C. J., Luo, R. F., Vogel, H., Banaei, N., & Ho, D. Y. (2011). Brain Abscess Caused by Phaeoacremonium parasiticum in an Immunocompromised Patient. JOURNAL OF CLINICAL MICROBIOLOGY, 49(3), 1171-1174.

Treatment of Acyclovir-Resistant Herpes Simplex Virus with Continuous Infusion of High-Dose Acyclovir in Hematopoietic Cell Transplant Patients
Kim, J. H., Schaenman, J. M., Ho, D. Y., & Brown, J. My. (2011). Treatment of Acyclovir-Resistant Herpes Simplex Virus with Continuous Infusion of High-Dose Acyclovir in Hematopoietic Cell Transplant Patients. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 17(2), 259-264.

Yield of diagnostic procedures for invasive fungal infections in neutropenic febrile patients with chest computed tomography abnormalities
Ho, D. Y., Lin, M., Schaenman, J., Rosso, F., Leung, A. Nc., & Montoya, J. G. (2011). Yield of diagnostic procedures for invasive fungal infections in neutropenic febrile patients with chest computed tomography abnormalities. MYCOSES, 54(1), 59-70.

Safety and immunogenicity of inactivated, Vero cell culture-derived whole virus influenza A/H5N1 vaccine given alone or with aluminum hydroxide adjuvant in healthy adults
Keitel, W. A., Dekker, C. L., Mink, Ca., Campbell, J. D., Edwards, K. M., & Hill, H. (2009). Safety and immunogenicity of inactivated, Vero cell culture-derived whole virus influenza A/H5N1 vaccine given alone or with aluminum hydroxide adjuvant in healthy adults. VACCINE, 27(47), 6642-6648.

Varicella Zoster Virus
Ho DY, Arvin Am, & Newland JG. (2009). Varicella Zoster Virus. In: Yu VL, Weber R, Raoult D (eds.), Antinicrobial Therapy and Vaccines 3rd edition.

Immunogenicity, safety and consistency of new trivalent inactivated influenza vaccine
Talbot, H. K., Keitel, W., Cate, T. R., Treanor, J., Campbell, J., & Edwards, K. M. (2008). Immunogenicity, safety and consistency of new trivalent inactivated influenza vaccine. VACCINE, 26(32), 4057-4061.

Varicella Zoster Virus Infections
Ho DY, & Arvin AM. (2008). Varicella Zoster Virus Infections. In: Blume KG, Negrin RS, Foramn SJ, Appelbaum (eds.), Thomas? Hematopoietic Cell Transplantation 4th edition., Chapter 92.

Treating disseminated fusariosis: amphotericin B, voriconazole or both?
Ho, D. Y., Lee, J. D., Rosso, F., & Montoya, J. G. (2007). Treating disseminated fusariosis: amphotericin B, voriconazole or both?. MYCOSES, 50(3), 227-231.

Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults
Lee, A. L., Dumas, T. C., Tarapore, P. E., Webster, B. R., Ho, D. Y., & Sapolsky, R. M. (2003). Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults. JOURNAL OF NEUROCHEMISTRY, 86(5), 1079-1088.

Anaphylactoid reaction to ciprofloxacin
Ho, D. Y., Song, J. C., & Wang, C. C. (2003). Anaphylactoid reaction to ciprofloxacin. ANNALS OF PHARMACOTHERAPY, 37(7-8), 1018-1023.

Interactions among ascorbate, dehydroascorbate and glucose transport in cultured hippocampal neurons and glia
Patel, M., McIntosh, L., Bliss, T., Ho, D., & Sapolsky, R. (2001). Interactions among ascorbate, dehydroascorbate and glucose transport in cultured hippocampal neurons and glia. BRAIN RESEARCH, 916(1-2), 127-135.

Neuroprotective effects of an adenoviral vector expressing the glucose transporter: a detailed description of the mediating cellular events
Gupta, A., Ho, D. Y., Brooke, S., Franklin, L., Roy, M., & Sapolsky, R. M. (2001). Neuroprotective effects of an adenoviral vector expressing the glucose transporter: a detailed description of the mediating cellular events. BRAIN RESEARCH, 908(1), 49-57.

Calbindin D28K overexpression protects striatal neurons from transient focal cerebral ischemia
Yenari, M. A., Minami, M., Sun, G. H., Meier, T. J., Kunis, D. M., & Steinberg, G. K. (2001). Calbindin D28K overexpression protects striatal neurons from transient focal cerebral ischemia. STROKE, 32(4), 1028-1035.

Sparing of neuronal function postseizure with gene therapy
MCLAUGHLIN, J., Roozendaal, B., Dumas, T., Gupta, A., Ajilore, O., & Sapolsky, R. (2000). Sparing of neuronal function postseizure with gene therapy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(23), 12804-12809.

Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission
Dumas, T. C., McLaughlin, J. R., Ho, D. Y., Lawrence, M. S., & Sapolsky, N. M. (2000). Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission. EXPERIMENTAL NEUROLOGY, 166(1), 180-189.

Neuroprotective potential of a viral vector system induced by a neurological insult
Ozawa, C. R., Ho, J. J., Tsai, D. J., Ho, D. Y., & Sapolsky, R. M. (2000). Neuroprotective potential of a viral vector system induced by a neurological insult. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(16), 9270-9275.

Limitations in the neuroprotective potential of gene therapy with Bcl-2
Phillips, R. G., Lawrence, M. S., Ho, D. Y., & Sapolsky, R. M. (2000). Limitations in the neuroprotective potential of gene therapy with Bcl-2. BRAIN RESEARCH, 859(2), 202-206.

An adenoviral vector expressing the glucose transporter protects cultured striatal neurons from 3-nitropropionic acid
Fink, S. L., Ho, D. Y., MCLAUGHLIN, J., & Sapolsky, R. M. (2000). An adenoviral vector expressing the glucose transporter protects cultured striatal neurons from 3-nitropropionic acid. BRAIN RESEARCH, 859(1), 21-25.

Delivery of herpes simplex virus amplicon-based vectors to the dentate gyrus does not alter hippocampal synaptic transmission in vivo
Dumas, T. D., McLaughlin, J. R., Ho, D. Y., Meier, T. J., & Sapolsky, R. M. (1999). Delivery of herpes simplex virus amplicon-based vectors to the dentate gyrus does not alter hippocampal synaptic transmission in vivo. GENE THERAPY, 6(10), 1679-1684.

Calbindin D-28K gene transfer via herpes simplex virus amplicon vector decreases hippocampal damage in vivo following neurotoxic insults
Phillips, R. G., Meier, T. J., Giuli, L. C., McLaughlin, J. R., Ho, D. Y., & Sapolsky, M. R. (1999). Calbindin D-28K gene transfer via herpes simplex virus amplicon vector decreases hippocampal damage in vivo following neurotoxic insults. JOURNAL OF NEUROCHEMISTRY, 73(3), 1200-1205.

Gene transfer therapy for cerebral ischemia
Yenari, M. A., Fink, S. L., Lawrence, M., Sun, G. H., MCLAUGHLIN, J., & Steinberg, G. K. (1999). Gene transfer therapy for cerebral ischemia. PHARMACOLOGY OF CEREBRAL ISCHEMIA 1998, 453-465.

Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy
Yenari, M. A., Fink, S. L., Sun, G. H., Chang, L. K., Patel, M. K., & Steinberg, G. K. (1998). Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy. ANNALS OF NEUROLOGY, 44(4), 584-591.

Gene transfer of calbindin D-28k cDNA via herpes simplex virus amplicon vector decreases cytoplasmic calcium ion response and enhances neuronal survival following glutamatergic challenge but not following cyanide
Meier, T. J., Ho, D. Y., Park, T. S., & Sapolsky, R. M. (1998). Gene transfer of calbindin D-28k cDNA via herpes simplex virus amplicon vector decreases cytoplasmic calcium ion response and enhances neuronal survival following glutamatergic challenge but not following cyanide. JOURNAL OF NEUROCHEMISTRY, 71(3), 1013-1023.

The ins and outs of on and off
Sapolsky, R. M., Ho, D. Y., & MCLAUGHLIN, J. (1998). The ins and outs of on and off. NATURE BIOTECHNOLOGY, 16(6), 516-516.

Gene transfer therapy for cerebral ischemia
Yenari MA, Fink SL, Lawrence MS, Sun GH, McLaughlin J, & Steinberg G. (1998). Gene transfer therapy for cerebral ischemia. In: Krieglstein J and Oberpichler-Schwenk H (eds.), Pharmacology of Cerebral Ischemia, Medpharm, Stuttgart.

Increased expression of calbindin D-28k via herpes simplex virus amplicon vector decreases calcium ion mobilization and enhances neuronal survival after hypoglycemic challenge
Meier, T. J., Ho, D. Y., & Sapolsky, R. M. (1997). Increased expression of calbindin D-28k via herpes simplex virus amplicon vector decreases calcium ion mobilization and enhances neuronal survival after hypoglycemic challenge. JOURNAL OF NEUROCHEMISTRY, 69(3), 1039-1047.

Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke
Lawrence, M. S., McLaughlin, J. R., Sun, G. H., Ho, D. Y., McIntosh, L., & Steinberg, G. K. (1997). Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 17(7), 740-744.

Gene therapy for the nervous system
Ho, D. Y., & Sapolsky, R. M. (1997). Gene therapy for the nervous system. SCIENTIFIC AMERICAN, 276(6), 116-120.

Defective herpes simplex virus vectors expressing the rat brain stress-inducible heat shock protein 72 protect cultured neurons from severe heat shock
Fink, S. L., Chang, L. K., Ho, D. Y., & Sapolsky, R. M. (1997). Defective herpes simplex virus vectors expressing the rat brain stress-inducible heat shock protein 72 protect cultured neurons from severe heat shock. JOURNAL OF NEUROCHEMISTRY, 68(3), 961-969.

Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system
Ho, D. Y., McLaughlin, J. R., & Sapolsky, R. M. (1996). Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system. MOLECULAR BRAIN RESEARCH, 41(1-2), 200-209.

Energy and glutamate dependency of 3-nitropropionic acid neurotoxicity in culture
Fink, S. L., Ho, D. Y., & Sapolsky, R. M. (1996). Energy and glutamate dependency of 3-nitropropionic acid neurotoxicity in culture. EXPERIMENTAL NEUROLOGY, 138(2), 298-304.

Overexpression of the glucose transporter gene with a Herpes simplex viral vector protects striatal neurons against stroke
Lawrence, M. S., Sun, G. H., Kunis, D. M., Saydam, T. C., Dash, R., & Steinberg, G. K. (1996). Overexpression of the glucose transporter gene with a Herpes simplex viral vector protects striatal neurons against stroke. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 16(2), 181-185.

Overexpression of bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo
Lawrence, M. S., Ho, D. Y., Sun, G. H., Steinberg, G. K., & Sapolsky, R. M. (1996). Overexpression of bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo. JOURNAL OF NEUROSCIENCE, 16(2), 486-496.

Herpes simplex viral vectors expressing Bcl-2 are neuroprotective against focal cerebral ischemia
Yenari, M. A., Lawrence, M. S., Sun, G. H., Ho, D. Y., Kunis, D. M., & Steinberg, G. K. (1996). Herpes simplex viral vectors expressing Bcl-2 are neuroprotective against focal cerebral ischemia. WISSENSCHAFTLICHE verlagsgesellschaft mbh.

A herpes simplex virus vector overexpressing the glucose transporter gene protects the rat dentate gyrus from an antimetabolite toxin
Dash, R., Lawrence, M., Ho, D., & Sapolsky, R. (1996). A herpes simplex virus vector overexpressing the glucose transporter gene protects the rat dentate gyrus from an antimetabolite toxin. EXPERIMENTAL NEUROLOGY, 137(1), 43-48.

Herpes simplex viral vectors expressing bcl-2 are neuroprotective against focal ischemia
Yenari M, Lawrence M, Sun G, Ho DY, Kunis D, & Steinberg G. (1996). Herpes simplex viral vectors expressing bcl-2 are neuroprotective against focal ischemia. In: Krieglstein J (ed.) Pharmacology of Cerebral Ischemia, Medpharm, Stuttgart.

HERPES-SIMPLEX VIRUS VECTORS OVEREXPRESSING THE GLUCOSE-TRANSPORTER GENE PROTECT AGAINST SEIZURE-INDUCED NEURON LOSS
Lawrence, M. S., Ho, D. Y., Dash, R., & Sapolsky, R. M. (1995). HERPES-SIMPLEX VIRUS VECTORS OVEREXPRESSING THE GLUCOSE-TRANSPORTER GENE PROTECT AGAINST SEIZURE-INDUCED NEURON LOSS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 92(16), 7247-7251.

DEFECTIVE HERPES-SIMPLEX VIRUS VECTORS EXPRESSING THE RAT-BRAIN GLUCOSE-TRANSPORTER PROTECT CULTURED NEURONS FROM NECROTIC INSULTS
Ho, D. Y., Saydam, T. C., Fink, S. L., Lawrence, M. S., & Sapolsky, R. M. (1995). DEFECTIVE HERPES-SIMPLEX VIRUS VECTORS EXPRESSING THE RAT-BRAIN GLUCOSE-TRANSPORTER PROTECT CULTURED NEURONS FROM NECROTIC INSULTS. JOURNAL OF NEUROCHEMISTRY, 65(2), 842-850.

HERPES-SIMPLEX VIRUS VECTOR SYSTEM - ANALYSIS OF ITS IN-VIVO AND IN-VITRO CYTOPATHIC EFFECTS
Ho, D. Y., Fink, S. L., Lawrence, M. S., Meier, T. J., Saydam, T. C., & Sapolsky, R. M. (1995). HERPES-SIMPLEX VIRUS VECTOR SYSTEM - ANALYSIS OF ITS IN-VIVO AND IN-VITRO CYTOPATHIC EFFECTS. JOURNAL OF NEUROSCIENCE METHODS, 57(2), 205-215.

MULTIPLE VECTORS EFFECTIVELY ACHIEVE GENE-TRANSFER IN A MURINE CARDIAC TRANSPLANTATION MODEL - IMMUNOSUPPRESSION WITH TGF-BETA-1 OR VIL-10
Qin, L. H., Chavin, K. D., Ding, Y. Z., Favaro, J. P., Woodward, J. E., & Bromberg, J. S. (1995). MULTIPLE VECTORS EFFECTIVELY ACHIEVE GENE-TRANSFER IN A MURINE CARDIAC TRANSPLANTATION MODEL - IMMUNOSUPPRESSION WITH TGF-BETA-1 OR VIL-10. TRANSPLANTATION, 59(6), 809-816.

Use of herpes simplex virus vectors for protection from necrotic neuron death
Ho DY, Lawrence M, Meier T, Fink S, Dash R, & Sapolsky R. (1995). Use of herpes simplex virus vectors for protection from necrotic neuron death. In: Kaplitt M, Loewy A (eds.), Viral Vectors, Academic Press.

Necrotic neuron death, its exacerbation by stress, and its diminution by gene transfer approaches
Sapolsky R, & Ho DY. (1995). Necrotic neuron death, its exacerbation by stress, and its diminution by gene transfer approaches. In: Ottoson D, Bartfai T, Hokfelt T, Fuxe K (eds.) Challenges and Perspectives in Neuroscience, Wenner-Gren International Series, Pergamon.

AMPLICON-BASED HERPES-SIMPLEX VIRUS VECTORS
Ho, D. Y. (1994). AMPLICON-BASED HERPES-SIMPLEX VIRUS VECTORS. METHODS IN CELL BIOLOGY, VOL 43, 43, 191-210.

ALTERING CENTRAL-NERVOUS-SYSTEM PHYSIOLOGY WITH A DEFECTIVE HERPES-SIMPLEX VIRUS VECTOR EXPRESSING THE GLUCOSE TRANSPORTER GENE
Ho, D. Y., Mocarski, E. S., & Sapolsky, R. M. (1993). ALTERING CENTRAL-NERVOUS-SYSTEM PHYSIOLOGY WITH A DEFECTIVE HERPES-SIMPLEX VIRUS VECTOR EXPRESSING THE GLUCOSE TRANSPORTER GENE. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 90(8), 3655-3659.

NEUTRALIZING EPITOPES ON HERPES-SIMPLEX VIRUS-1-EXPRESSED ROTAVIRUS-VP7 ARE DEPENDENT ON COEXPRESSION OF OTHER ROTAVIRUS PROTEINS
Dormitzer, P. R., Ho, D. Y., MACKOW, E. R., Mocarski, E. S., & Greenberg, H. B. (1992). NEUTRALIZING EPITOPES ON HERPES-SIMPLEX VIRUS-1-EXPRESSED ROTAVIRUS-VP7 ARE DEPENDENT ON COEXPRESSION OF OTHER ROTAVIRUS PROTEINS. VIROLOGY, 187(1), 18-32.

HERPES-SIMPLEX VIRUS LATENCY - MOLECULAR ASPECTS
Ho, D. Y. (1992). HERPES-SIMPLEX VIRUS LATENCY - MOLECULAR ASPECTS. PROGRESS IN MEDICAL VIROLOGY, 39, 76-115.

HERPES-SIMPLEX VIRUS LATENT RNA (LAT) IS NOT REQUIRED FOR LATENT INFECTION IN THE MOUSE
Ho, D. Y., & Mocarski, E. S. (1989). HERPES-SIMPLEX VIRUS LATENT RNA (LAT) IS NOT REQUIRED FOR LATENT INFECTION IN THE MOUSE. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 86(19), 7596-7600.

BETA-GALACTOSIDASE AS A MARKER IN THE PERIPHERAL AND NEURAL TISSUES OF THE HERPES-SIMPLEX VIRUS-INFECTED MOUSE
Ho, D. Y., & Mocarski, E. S. (1988). BETA-GALACTOSIDASE AS A MARKER IN THE PERIPHERAL AND NEURAL TISSUES OF THE HERPES-SIMPLEX VIRUS-INFECTED MOUSE. VIROLOGY, 167(1), 279-283.