Chris Holsinger

Head and neck surgeon, Thyroid and parathyroid surgeon, Head and neck surgical oncologist

Professor of Otolaryngology - Head and Neck Surgery at the Stanford University Medical Center
Dr. Holsinger is Professor and Chief of Head and Neck Surgery at Stanford University Medical Center, where he also leads the Head and Neck Oncology Program at the Stanford Cancer Center. From 2003-2013, Dr. Holsinger worked at the Department of Head and Neck Surgery at the University of Texas M.D. Anderson Cancer Center where he founded the Program in Minimally Invasive and Endoscopic Head and Neck Surgery.

Dr. Holsinger received his medical degree from Vanderbilt School of Medicine, completed his internship and residency at Baylor College of Medicine and his Fellowship in head and neck surgical oncology at The University of Texas M. D. Anderson Cancer Center. In 2003, he was awarded Fulbright Scholarship to study surgery at the University of Paris with Professor Ollivier Laccourreye and with Professor Wolfgang Steiner at the Georg-August University in Göttingen.

Dr. Holsinger’s surgical practice focuses on the surgical management of benign and malignant diseases of the thyroid, as well as head and neck cancers. His areas of research interest include endoscopic head and neck surgery, including robotic thyroidectomy, transoral robotic surgery and transoral laser microsurgery, as well as time-honoured approaches of conservation laryngeal surgery, supracricoid partial laryngectomy.

Dr. Holsinger leads several prospective clinical trails, through NCI-funded cooperative groups. He currently serves as the principal investigator of RTOG1221, a Randomized Trial of Transoral Endoscopic Head And Neck Surgery followed by Risk-Based IMRT and Weekly Cisplatin versus IMRT and Weekly Cisplatin for HPV Negative Oropharynx Cancer.

Dr. Holsinger has authored or co-authored numerous articles and abstracts, which have appeared in publications such as the New England Journal of Medicine, Journal of the American College of Surgeons, the Journal of Clinical Oncology, Clinical Cancer Research, Head & Neck, Laryngoscope, and the Archives of Otolaryngology—Head and Neck Surgery.

Board-certified by the American Board of Otolaryngology, Dr. Holsinger is a member of numerous societies including the American College of Surgeons, the American Society of Clinical Oncology, and the American Head and Neck Society.

Head and Neck Cancer Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Fellowship: MD Anderson Cancer Center (2003) TX

Board Certification: Otolaryngology, American Board of Otolaryngology (2002)

Residency: Baylor College of Medicine (2001) TX

Internship: Baylor College of Medicine (1996) TX

Medical Education: Vanderbilt University School of Medicine (1995) TN

Fulbright Scholarship, Université de Paris V, Rene Descartes Sorbonne Paris Cité, France, Post-doctoral Fellowship in Head and Neck Surgery (2003)

Fellowship, Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, Head and Neck Surgical Oncology (2003)

Residency, Bobby R. Alford Department of Otolaryngology--Head and Neck Surgery, Baylor College of Medicine, Otolaryngology--Head and Neck Surgery (2001)

Internship, Debakey Department of Surgery Baylor College of Medicine, General Surgery (1997)

MD, Vanderbilt University School of Medicine (1995)

Administrative Appointments

Member, Stanford Cancer Institute (2013 - Present)

Director, Head and Neck Cancer Care Program, Stanford Cancer Center (2013 - Present)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Lateral Pharyngotomy for Selected Invasive Squamous Cell Carcinoma of the Lateral Oropharynx. Part II: When and Why
Laccourreye, O., Benito, J., Garcia, D., Menard, M., Bonfils, P., & Holsinger, C. (2013). Lateral Pharyngotomy for Selected Invasive Squamous Cell Carcinoma of the Lateral Oropharynx. Part II: When and Why. LARYNGOSCOPE, 123(11), 2718-2722.

Lateral pharyngotomy for selected invasive squamous cell carcinoma of the lateral oropharynx--part I: how.
Laccourreye, O., Benito, J., Menard, M., Garcia, D., Malinvaud, D., & Holsinger, C. (2013). Lateral pharyngotomy for selected invasive squamous cell carcinoma of the lateral oropharynx--part I: how. Laryngoscope, 123(11), 2712-2717.

Lateral Pharyngotomy for Selected Invasive Squamous Cell Carcinoma of the Lateral Oropharynx-Part I: How
Laccourreye, O., Benito, J., Menard, M., Garcia, D., Malinvaud, D., & Holsinger, C. (2013). Lateral Pharyngotomy for Selected Invasive Squamous Cell Carcinoma of the Lateral Oropharynx-Part I: How. LARYNGOSCOPE, 123(11), 2712-2717.

Conventional transoral surgery for stage III squamous cell carcinoma of the tonsillar region
Laccourreye, O., Malinvaud, D., Alzahrani, H., Menard, M., Garcia, D., & Holsinger, F. C. (2013). Conventional transoral surgery for stage III squamous cell carcinoma of the tonsillar region. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 35(5), 653-659.

Robot-Assisted Selective Neck Dissection of Levels II to V via a Modified Facelift or Retroauricular Approach
Park, Y. M., Holsinger, F. C., Kim, W. S., Park, S. C., Lee, E. J., & Koh, Y. W. (2013). Robot-Assisted Selective Neck Dissection of Levels II to V via a Modified Facelift or Retroauricular Approach. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 148(5), 778-785.

Biomarker-Directed Therapy of Squamous Carcinomas of the Head and Neck: Targeting PI3K/PTEN/mTOR Pathway
Holsinger, F. C., Piha-Paul, S. A., Janku, F., Hong, D. S., Atkins, J. T., & Kurzrock, R. (2013). Biomarker-Directed Therapy of Squamous Carcinomas of the Head and Neck: Targeting PI3K/PTEN/mTOR Pathway. JOURNAL OF CLINICAL ONCOLOGY, 31(9), E137-E140.

A 13-Gene Signature Prognostic of HPV-Negative OSCC: Discovery and External Validation
Lohavanichbutr, P., Mendez, E., Holsinger, F. C., Rue, T. C., Zhang, Y., & Chen, C. (2013). A 13-Gene Signature Prognostic of HPV-Negative OSCC: Discovery and External Validation. CLINICAL CANCER RESEARCH, 19(5), 1197-1203.

Endoscopic supraomohyoid neck dissection via a retroauricular or modified facelift approach: Preliminary results.
Byeon, H. K., Holsinger, F. C., Koh, Y. W., Ban, M. J., Ha, J. G., & Choi, E. C. (2013). Endoscopic supraomohyoid neck dissection via a retroauricular or modified facelift approach: Preliminary results. Head & neck.

Long-term functional and survival outcomes after induction chemotherapy and risk-based definitive therapy for locally advanced squamous cell carcinoma of the head and neck.
Hutcheson, K. A., Lewin, J. S., Holsinger, F. C., Steinhaus, G., Lisec, A., & Kies, M. S. (2013). Long-term functional and survival outcomes after induction chemotherapy and risk-based definitive therapy for locally advanced squamous cell carcinoma of the head and neck. Head & neck.

Transoral resection of pharyngeal cancer: Summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6-7, 2011, Arlington, Virginia
Adelstein, D. J., Ridge, J. A., Brizel, D. M., Holsinger, F. C., Haughey, B. H., & Ullmann, C. D. (2012). Transoral resection of pharyngeal cancer: Summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6-7, 2011, Arlington, Virginia. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 34(12), 1681-1703.

Late dysphagia after radiotherapy-based treatment of head and neck cancer
Hutcheson, K. A., Lewin, J. S., Barringer, D. A., Lisec, A., Gunn, G. B., & Holsinger, F. C. (2012). Late dysphagia after radiotherapy-based treatment of head and neck cancer. CANCER, 118(23), 5793-5799.

Oropharynx Cancer
Skinner, H. D., Holsinger, F. C., & Beadle, B. M. (2012). Oropharynx Cancer. CURRENT PROBLEMS IN CANCER, 36(6), 334-415.

Functional and Oncological Outcomes of Primary Versus Salvage Transoral Laser Microsurgery for Supraglottic Carcinoma
Hutcheson, K. A., Jantharapattana, K., Barringer, D. A., Lewin, J. S., & Holsinger, F. C. (2012). Functional and Oncological Outcomes of Primary Versus Salvage Transoral Laser Microsurgery for Supraglottic Carcinoma. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 121(10), 664-670.

Gene Expression in Uninvolved Oral Mucosa of OSCC Patients Facilitates Identification of Markers Predictive of OSCC Outcomes
Lohavanichbutr, P., Houck, J., Doody, D. R., Wang, P., Mendez, E., & Chen, C. (2012). Gene Expression in Uninvolved Oral Mucosa of OSCC Patients Facilitates Identification of Markers Predictive of OSCC Outcomes. PLOS ONE, 7(9).

Trade-Off Between Survival and Laryngeal Preservation in Advanced Laryngeal Cancer: The Otorhinolaryngology Patient's Perspective
Laccourreye, O., Malinvaud, D., Holsinger, F. C., Consoli, S., Menard, M., & Bonfils, P. (2012). Trade-Off Between Survival and Laryngeal Preservation in Advanced Laryngeal Cancer: The Otorhinolaryngology Patient's Perspective. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 121(9), 570-575.

Reconstruction after Robotic Head and Neck Surgery: When and Why
Longfield, E. A., Holsinger, F. C., & Selber, J. C. (2012). Reconstruction after Robotic Head and Neck Surgery: When and Why. JOURNAL OF RECONSTRUCTIVE MICROSURGERY, 28(7), 445-449.

Robotic Harvest of the Latissimus Dorsi Muscle: Laboratory and Clinical Experience
Selber, J. C., Baumann, D. P., & Holsinger, C. F. (2012). Robotic Harvest of the Latissimus Dorsi Muscle: Laboratory and Clinical Experience. JOURNAL OF RECONSTRUCTIVE MICROSURGERY, 28(7), 457-464.

Transoral robotic surgery: A multicenter study to assess feasibility, safety, and surgical margins
Weinstein, G. S., O'Malley, B. W., Magnuson, J. S., Carroll, W. R., Olsen, K. D., & Holsinger, F. C. (2012). Transoral robotic surgery: A multicenter study to assess feasibility, safety, and surgical margins. LARYNGOSCOPE, 122(8), 1701-1707.

Osteosarcoma of the jaw in children and young adults
Huh, W. W., Holsinger, F. C., Levy, A., Palla, F. S. L., & Anderson, P. M. (2012). Osteosarcoma of the jaw in children and young adults. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 34(7), 981-984.

Robotic Latissimus Dorsi Muscle Harvest: A Case Series
Selber, J. C., Baumann, D. P., & Holsinger, F. C. (2012). Robotic Latissimus Dorsi Muscle Harvest: A Case Series. PLASTIC AND RECONSTRUCTIVE SURGERY, 129(6), 1305-1312.

Robotic transaxillary thyroidectomy with gasless approach in a girl with goitre
Kandil, E., Noureldine, S., Khalek, M. A., Aslam, R., Ekaidi, I., & Holsinger, F. C. (2012). Robotic transaxillary thyroidectomy with gasless approach in a girl with goitre. INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY, 8(2), 210-214.

Functional Organ Preservation for Laryngeal Cancer: Past, Present and Future
Nakayama, M., Laccourreye, O., Holsinger, F. C., Okamoto, M., & Hayakawa, K. (2012). Functional Organ Preservation for Laryngeal Cancer: Past, Present and Future. JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 42(3), 155-160.

Initial experience using robot- assisted transaxillary thyroidectomy for Graves' disease
Kandil, E., Noureldine, S., Khalek, M. A., Alrasheedi, S., Aslam, R., & Bellows, C. F. (2011). Initial experience using robot- assisted transaxillary thyroidectomy for Graves' disease. JOURNAL OF VISCERAL SURGERY, 148(6), E447-E451.

ASPIRATION AFTER SUPRACRICOID PARTIAL LARYNGECTOMY: INCIDENCE, RISK FACTORS, MANAGEMENT, AND OUTCOMES
Benito, J., Holsinger, F. C., Perez-Martin, A., Garcia, D., Weinstein, G. S., & Laccourreye, O. (2011). ASPIRATION AFTER SUPRACRICOID PARTIAL LARYNGECTOMY: INCIDENCE, RISK FACTORS, MANAGEMENT, AND OUTCOMES. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 33(5), 679-685.

Robot assisted transaxillary surgery (RATS) for the removal of thyroid and parathyroid glands
Landry, C. S., Grubbs, E. G., Morris, G. S., Turner, N. S., Holsinger, F. C., & Perrier, N. D. (2011). Robot assisted transaxillary surgery (RATS) for the removal of thyroid and parathyroid glands. SURGERY, 149(4), 549-555.

Sinonasal and nasopharyngeal applications of the hand-held CO2 laser fiber
Agarwal, G., Kupferman, M. E., Holsinger, F. C., & Hanna, E. Y. (2011). Sinonasal and nasopharyngeal applications of the hand-held CO2 laser fiber. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 1(2), 109-112.

Initial experience with transoral robotic surgery using the da VinciA (R) surgical system
Simon, C., El-Baba, B., Albrecht, T., Holsinger, F. C., & Plinkert, P. K. (2011). Initial experience with transoral robotic surgery using the da VinciA (R) surgical system. HNO, 59(3), 261-265.

Robotic Thyroid Surgery: An Initial Experience with North American Patients
Kuppersmith, R. B., & Holsinger, F. C. (2011). Robotic Thyroid Surgery: An Initial Experience with North American Patients. LARYNGOSCOPE, 121(3), 521-526.

Transoral robotic-assisted thyroidectomy with central neck dissection: preclinical cadaver feasibility study and proposed surgical technique.
Richmon, J. D., Holsinger, F. C., Kandil, E., Moore, M. W., Garcia, J. A., & Tufano, R. P. (2011). Transoral robotic-assisted thyroidectomy with central neck dissection: preclinical cadaver feasibility study and proposed surgical technique. Journal of robotic surgery, 5(4), 279-282.

CRTC1/MAML2 fusion transcript in central mucoepidermoid carcinoma of mandible-diagnostic and histogenetic implications
Bell, D., Holsinger, C. F., & El-Naggar, A. K. (2010). CRTC1/MAML2 fusion transcript in central mucoepidermoid carcinoma of mandible-diagnostic and histogenetic implications. ANNALS OF DIAGNOSTIC PATHOLOGY, 14(6), 396-401.

Prereferral Head and Neck Cancer Treatment Compliance With National Comprehensive Cancer Network Treatment Guidelines
Lewis, C. M., Hessel, A. C., Roberts, D. B., Guo, Y. Z., Holsinger, F. C., & Weber, R. S. (2010). Prereferral Head and Neck Cancer Treatment Compliance With National Comprehensive Cancer Network Treatment Guidelines. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 136(12), 1205-1211.

CANDIDATE DOSIMETRIC PREDICTORS OF LONG-TERM SWALLOWING DYSFUNCTION AFTER OROPHARYNGEAL INTENSITY-MODULATED RADIOTHERAPY
Schwartz, D. L., Hutcheson, K., Barringer, D., Tucker, S. L., Kies, M., & Lewin, J. S. (2010). CANDIDATE DOSIMETRIC PREDICTORS OF LONG-TERM SWALLOWING DYSFUNCTION AFTER OROPHARYNGEAL INTENSITY-MODULATED RADIOTHERAPY. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(5), 1356-1365.

Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: A 45-year multi-institutional review
Holsinger, F. C., Hafemeister, A. C., Hicks, M. J., Sulek, M., Huh, W. W., & Friedman, E. M. (2010). Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: A 45-year multi-institutional review. ENT-EAR NOSE & THROAT JOURNAL, 89(11), 534-?.

A Shifting Paradigm for Patients with Head and Neck Cancer: Transoral Robotic Surgery (TORS)
Bhayani, M. K., Holsinger, F. C., & Lai, S. Y. (2010). A Shifting Paradigm for Patients with Head and Neck Cancer: Transoral Robotic Surgery (TORS). ONCOLOGY-NEW YORK, 24(11), 1010-1015.

SIMPLE CAROTID-SPARING INTENSITY-MODULATED RADIOTHERAPY TECHNIQUE AND PRELIMINARY EXPERIENCE FOR T1-2 GLOTTIC CANCER
Rosenthal, D. I., Fuller, C. D., Barker, J. L., Mason, B., Garcia, J. A., & Ang, K. K. (2010). SIMPLE CAROTID-SPARING INTENSITY-MODULATED RADIOTHERAPY TECHNIQUE AND PRELIMINARY EXPERIENCE FOR T1-2 GLOTTIC CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 77(2), 455-461.

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer
Byers, L. A., Holsinger, F. C., Kies, M. S., William, W. N., El-Naggar, A. K., & Heymach, J. V. (2010). Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer. MOLECULAR CANCER THERAPEUTICS, 9(6), 1755-1763.

CURRENT CONCEPTS AND NEW HORIZONS IN CONSERVATION LARYNGEAL SURGERY: AN IMPORTANT PART OF MULTIDISCIPLINARY CARE
Holsinger, F. C., Nussenbaum, B., Nakayama, M., Saraiya, S., Sewnaik, A., & McWhorter, A. J. (2010). CURRENT CONCEPTS AND NEW HORIZONS IN CONSERVATION LARYNGEAL SURGERY: AN IMPORTANT PART OF MULTIDISCIPLINARY CARE. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 32(5), 656-665.

The Emergence of Endoscopic Head and Neck Surgery
Holsinger, F. C., Sweeney, A. D., Jantharapattana, K., Salem, A., Weber, R. S., & Grant, D. G. (2010). The Emergence of Endoscopic Head and Neck Surgery. CURRENT ONCOLOGY REPORTS, 12(3), 216-222.

TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma
Kupferman, M. E., Jiffar, T., El-Naggar, A., Yilmaz, T., Zhou, G., & Myers, J. N. (2010). TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma. ONCOGENE, 29(14), 2047-2059.

Robotic Thyroidectomy: Operative Technique Using a Transaxillary Endoscopic Approach Without CO2 Insufflation
Holsinger, F. C., Terris, D. J., & Kuppersmith, R. B. (2010). Robotic Thyroidectomy: Operative Technique Using a Transaxillary Endoscopic Approach Without CO2 Insufflation. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA, 43(2), 381-?.

Transoral Robotic Free Flap Reconstruction of Oropharyngeal Defects: A Preclinical Investigation
Selber, J. C., Robb, G., Serletti, J. M., Weinstein, G., Weber, R., & Holsinger, F. C. (2010). Transoral Robotic Free Flap Reconstruction of Oropharyngeal Defects: A Preclinical Investigation. PLASTIC AND RECONSTRUCTIVE SURGERY, 125(3), 896-900.

Induction Chemotherapy and Cetuximab for Locally Advanced Squamous Cell Carcinoma of the Head and Neck: Results From a Phase II Prospective Trial
Kies, M. S., Holsinger, F. C., Lee, J. J., William, W. N., Glisson, B. S., & Papadimitrakopoulou, V. (2010). Induction Chemotherapy and Cetuximab for Locally Advanced Squamous Cell Carcinoma of the Head and Neck: Results From a Phase II Prospective Trial. JOURNAL OF CLINICAL ONCOLOGY, 28(1), 8-14.

FEASIBILITY AND SURGICAL APPROACH OF TRANSAXILLARY ROBOTIC THYROIDECTOMY WITHOUT CO2 INSUFFLATION
Lewis, C. M., Chung, W. Y., & Holsinger, F. C. (2010). FEASIBILITY AND SURGICAL APPROACH OF TRANSAXILLARY ROBOTIC THYROIDECTOMY WITHOUT CO2 INSUFFLATION. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 32(1), 121-126.

Robotic Axillary Thyroidectomy: Multi-Institutional Clinical Experience with the daVinci
Seybt, M., Kuppersmith, R. B., Holsinger, C., & Terris, D. J. (2010). Robotic Axillary Thyroidectomy: Multi-Institutional Clinical Experience with the daVinci. LARYNGOSCOPE, 120, S182-S182.

Secondary Tracheoesophageal Puncture With In-Office Transnasal Esophagoscopy
LeBert, B., McWhorter, A. J., Kunduk, M., Walvekar, R. R., Lewin, J. S., & Holsinger, F. C. (2009). Secondary Tracheoesophageal Puncture With In-Office Transnasal Esophagoscopy. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 135(12), 1190-1194.

Advanced approaches for thyroid surgery
Kuppersmith, R. B., Salem, A., & Holsinger, F. C. (2009). Advanced approaches for thyroid surgery. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 141(3), 340-342.

Transantral robotic access to the pituitary gland
Kupferman, M., DeMonte, F., Holsinger, F. C., & Hanna, E. (2009). Transantral robotic access to the pituitary gland. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 141(3), 413-415.

Platin-Based Exclusive Chemotherapy for Selected Patients With Squamous Cell Carcinoma of the Larynx and Pharynx
Holsinger, F. C., Lin, H. Y., Bassot, V., & Laccourreye, O. (2009). Platin-Based Exclusive Chemotherapy for Selected Patients With Squamous Cell Carcinoma of the Larynx and Pharynx. CANCER, 115(17), 3909-3918.

Extended Lateral Pharyngotomy for Selected Squamous Cell Carcinomas of the Lateral Tongue Base
Laccourreye, O., Seccia, V., Menard, M., Garcia, D., Vacher, C., & Holsinger, F. C. (2009). Extended Lateral Pharyngotomy for Selected Squamous Cell Carcinomas of the Lateral Tongue Base. ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 118(6), 428-434.

Durable Long-Term Remission With Chemotherapy Alone for Stage II to IV Laryngeal Cancer
Holsinger, F. C., Kies, M. S., Diaz, E. M., Gillenwater, A. M., Lewin, J. S., & Khuri, F. R. (2009). Durable Long-Term Remission With Chemotherapy Alone for Stage II to IV Laryngeal Cancer. JOURNAL OF CLINICAL ONCOLOGY, 27(12), 1976-1982.

Clinicopathological Analyses of Fifty Supracricoid Laryngectomized Specimens: Evidence Base Supporting Minimal Margins
Nakayama, M., Holsinger, C., Okamoto, M., Seino, Y., Miyamoto, S., & Hayashi, S. (2009). Clinicopathological Analyses of Fifty Supracricoid Laryngectomized Specimens: Evidence Base Supporting Minimal Margins. ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 71(6), 305-311.

Maxillary osteosarcoma associated with a dental implant - Report of a case and review of the literature regarding implant-related sarcomas
McGuff, H. S., Heim-Hall, J., Holsinger, F. C., Jones, A. A., O'Dell, D. S., & Hafemeister, A. C. (2008). Maxillary osteosarcoma associated with a dental implant - Report of a case and review of the literature regarding implant-related sarcomas. JOURNAL OF THE AMERICAN DENTAL ASSOCIATION, 139(8), 1052-1059.

Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck - A case-control study
Thariat, J., Ahamad, A., El-Naggar, A. K., Williams, M. D., Holsinger, F. C., & Garden, A. S. (2008). Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck - A case-control study. CANCER, 112(12), 2698-2709.

Horizontal supraglottic partial laryngectomy for selected squamous carcinoma of the vallecula
Laccourreye, L., Garcia, D., Menard, M., Brasnu, D., Laccourreye, O., & Holsinger, F. C. (2008). Horizontal supraglottic partial laryngectomy for selected squamous carcinoma of the vallecula. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 30(6), 756-764.

Functional analysis of swallowing outcomes after supracricoid partial laryngectomy
Lewin, J. S., Hutcheson, K. A., Barringer, D. A., May, A. H., Roberts, D. B., & Diaz, E. M. (2008). Functional analysis of swallowing outcomes after supracricoid partial laryngectomy. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 30(5), 559-566.

Recent advances in thyroid cancer. In brief.
Grubbs, E. G., Rich, T. A., Li, G., Sturgis, E. M., Younes, M. N., & Evans, D. B. (2008). Recent advances in thyroid cancer. In brief. Current problems in surgery, 45(3), 149-151.

Swing of the Pendulum: Optimizing Functional Outcomes in Larynx Cancer
Holsinger, F. C. (2008). Swing of the Pendulum: Optimizing Functional Outcomes in Larynx Cancer. CURRENT ONCOLOGY REPORTS, 10(2), 170-175.

Recent advances in thyroid cancer
Anonymous. (2008). Recent advances in thyroid cancer. CURRENT PROBLEMS IN SURGERY, 45(3), 156-?.

Videos in clinical medicine. Examination of the larynx and pharynx.
Holsinger, F. C., Kies, M. S., Weinstock, Y. E., Lewin, J. S., Hajibashi, S., & Laccourreye, O. (2008). Videos in clinical medicine. Examination of the larynx and pharynx. New England journal of medicine, 358(3).

Management of locally invasive well-differentiated thyroid cancer
Ark, N., Zemo, S., Nolen, D., Holsinger, E. C., & Weber, R. S. (2008). Management of locally invasive well-differentiated thyroid cancer. SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, 17(1), 145-?.

Robotic endoscopic surgery of the skull base
Hanna, E. Y., Holsinger, C., DeMonte, F., & Kupferman, M. (2007). Robotic endoscopic surgery of the skull base. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 133(12), 1209-1214.

The effect of dental artifacts, contrast media, and experience on Interobserver contouring variations in head and neck anatomy
O'Daniel, J. C., Rosenthal, D. I., Garden, A. S., Barker, J. L., Ahamad, A., & Dong, L. (2007). The effect of dental artifacts, contrast media, and experience on Interobserver contouring variations in head and neck anatomy. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 30(2), 191-198.

Primary adrenal natural killer/T-cell nasal type lymphoma: First case report in adults
Thompson, M. A., Habra, M. A., Routbort, M. J., Holsinger, F. C., Perrier, N. D., & Rodriguez, M. A. (2007). Primary adrenal natural killer/T-cell nasal type lymphoma: First case report in adults. AMERICAN JOURNAL OF HEMATOLOGY, 82(4), 299-303.

Swing of the surgical pendulum: A return to surgery for treatment of head and neck cancer in the 21st century?
Holsinger, F. C., & Weber, R. S. (2007). Swing of the surgical pendulum: A return to surgery for treatment of head and neck cancer in the 21st century?. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(2), S129-S131.

Laryngeal preservation in the era of chemoradiation: limitations of the current AJCC staging system.
Holsinger, F. C., & Diaz, E. M. (2006). Laryngeal preservation in the era of chemoradiation: limitations of the current AJCC staging system. Head & neck, 28(12), 1058-1060.

Sternocleidomastoid myofascial flap for reconstruction after composite resection of invasive squamous cell carcinoma of the tonsillar region: Technique and outcome
Laccourreye, O., Menard, M., Behm, E., Garcia, D., Cauchois, R., & Holsinger, F. C. (2006). Sternocleidomastoid myofascial flap for reconstruction after composite resection of invasive squamous cell carcinoma of the tonsillar region: Technique and outcome. LARYNGOSCOPE, 116(11), 2001-2006.

Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer
Holsinger, F. C., Funk, E., Roberts, D. B., & Diaz, E. M. (2006). Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 28(9), 779-784.

Resection of selected invasive squamous cell carcinoma of the pyriform sinus by means of the lateral pharyngotomy approach: The partial lateral pharyngectomy
Holsinger, F. C., Motamed, M., Garcia, D., Brasnu, D., Menard, M., & Laccourreye, O. (2006). Resection of selected invasive squamous cell carcinoma of the pyriform sinus by means of the lateral pharyngotomy approach: The partial lateral pharyngectomy. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 28(8), 705-711.

Use of the photonic band gap fiber assembly CO2 laser system in head and neck surgical oncology
Holsinger, F. C., Prichard, C. N., Shapira, G., Weisberg, O., Torres, D. S., & Weber, R. S. (2006). Use of the photonic band gap fiber assembly CO2 laser system in head and neck surgical oncology. LARYNGOSCOPE, 116(7), 1288-1290.

Elective neck dissection during salvage laryngectomy
Yao, M., Roebuck, J. C., Holsinger, F. C., & Myers, J. N. (2005). Elective neck dissection during salvage laryngectomy. AMERICAN JOURNAL OF OTOLARYNGOLOGY, 26(6), 388-392.

Technical refinements in the supracricoid partial laryngectomy to optimize functional outcomes
Holsinger, F. C., Laccourreye, O., Weinstein, G. S., Diaz, E. M., & McWhorter, A. J. (2005). Technical refinements in the supracricoid partial laryngectomy to optimize functional outcomes. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 201(5), 809-820.

Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck
Moore, B. A., Weber, R. S., Prieto, V., El-Naggar, A., Holsinger, F. C., & Clayman, G. L. (2005). Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck. LARYNGOSCOPE, 115(9), 1561-1567.

Thyroplasty type I with Montgomery implant among native French language speakers with unilateral laryngeal nerve paralysis
Laccourreye, O., El Sharkawy, L., Holsinger, F. C., Hans, S., Menard, M., & Brasnu, D. (2005). Thyroplasty type I with Montgomery implant among native French language speakers with unilateral laryngeal nerve paralysis. LARYNGOSCOPE, 115(8), 1411-1417.

Organ-preservation laryngeal surgery in the era of chemoradiation
Moore, B. A., Holsinger, F. C., Diaz, E. M., & Weber, R. S. (2005). Organ-preservation laryngeal surgery in the era of chemoradiation. CURRENT PROBLEMS IN CANCER, 29(4), 169-179.

Supracricoid partial laryngectomy: An organ-preservation surgery for laryngeal malignancy
Holsinger, C., Weinstein, G. S., & Laccourreye, O. (2005). Supracricoid partial laryngectomy: An organ-preservation surgery for laryngeal malignancy. CURRENT PROBLEMS IN CANCER, 29(4), 190-200.

Foreword.
Weber, R. S., & Holsinger, F. C. (2005). Foreword. Current problems in cancer, 29(4), 168-?.

Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region - II. An analysis of the incidence, related variables, and consequences of local recurrence
Laccourreye, O., Hans, S., Menard, M., Garcia, D., Brasnu, D., & Holsinger, C. (2005). Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region - II. An analysis of the incidence, related variables, and consequences of local recurrence. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 131(7), 592-599.

Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region - I. Technique, complications, and functional results
Holsinger, F. C., McWhorter, A. J., Menard, M., Garcia, D., & Laccourreye, O. (2005). Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region - I. Technique, complications, and functional results. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 131(7), 583-591.

Mortality risk from squamous cell skin cancer
Clayman, G. L., Lee, J. J., Holsinger, F. C., Zhou, X., Duvic, M., & Lippman, S. M. (2005). Mortality risk from squamous cell skin cancer. JOURNAL OF CLINICAL ONCOLOGY, 23(4), 759-765.

A simple method to expose the surgical field when performing a thyroplasty
Laccourreye, O., & Holsinger, F. C. (2005). A simple method to expose the surgical field when performing a thyroplasty. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 132(1), 108-109.

Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer
Schiff, B. A., McMurphy, A. B., Jasser, S. A., Younes, M. N., Doan, D., & Myers, J. N. (2004). Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer. CLINICAL CANCER RESEARCH, 10(24), 8594-8602.

Detection of plasminogen activators in oral cancer by laser capture microdissection combined with zymography
Curino, A., Patel, V., Nielsen, B. S., Iskander, A. J., Ensley, J. F., & Bugge, T. H. (2004). Detection of plasminogen activators in oral cancer by laser capture microdissection combined with zymography. ORAL ONCOLOGY, 40(10), 1026-1032.

Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer
Swan, E. A., Jasser, S. A., Holsinger, F. C., Doan, D., Bucana, C., & Myers, J. N. (2003). Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer. ORAL ONCOLOGY, 39(7), 648-655.

Epidermal growth factor receptor blockade potentiates apoptosis mediated by paclitaxel and leads to prolonged survival in a murine model of oral cancer
Holsinger, F. C., Doan, D. D., Jasser, S. A., Swan, E. A., Greenberg, J. S., & Myers, J. N. (2003). Epidermal growth factor receptor blockade potentiates apoptosis mediated by paclitaxel and leads to prolonged survival in a murine model of oral cancer. CLINICAL CANCER RESEARCH, 9(8), 3183-3189.

Squamous cell carcinoma of the buccal mucosa: One institution's experience with 119 previously untreated patients
Diaz, E. M., Holsinger, F. C., Zuniga, E. R., Roberts, D. B., & Sorensen, D. M. (2003). Squamous cell carcinoma of the buccal mucosa: One institution's experience with 119 previously untreated patients. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 25(4), 267-273.

Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade - A preliminary report
Myers, J. N., Holsinger, F. C., Bekele, B. N., Li, E., Jasser, S. A., & FIDLER, I. J. (2002). Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade - A preliminary report. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 128(8), 875-879.

Central mucoepidermoid carcinoma of the mandible - Tumorigenesis within a keratocyst
Holsinger, F. C., Owens, J. M., Raymond, A. K., & Myers, J. N. (2002). Central mucoepidermoid carcinoma of the mandible - Tumorigenesis within a keratocyst. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 128(6), 718-720.

An orthotopic nude mouse model of oral tongue squamous cell carcinoma
Myers, J. N., Holsinger, F. C., Jasser, S. A., Bekele, B. N., & FIDLER, I. J. (2002). An orthotopic nude mouse model of oral tongue squamous cell carcinoma. CLINICAL CANCER RESEARCH, 8(1), 293-298.

Hearing preservation in conservation surgery for vestibular schwannoma
Holsinger, F. C., Coker, N. J., & Jenkins, H. A. (2000). Hearing preservation in conservation surgery for vestibular schwannoma. AMERICAN JOURNAL OF OTOLOGY, 21(5), 695-700.

Computer based physician education
Jewett, B. S., Holsinger, C., Kuppersmith, R. B., & Buenting, J. E. (1998). Computer based physician education. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA, 31(2), 301-?.

The use of e-mail by otolaryngologists
Kuppersmith, R. B., Holsinger, C., & Jenkins, H. A. (1996). The use of e-mail by otolaryngologists. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 122(9), 921-922.

SUCCESSFUL TREATMENT OF INVASIVE BRONCHIAL ASPERGILLOSIS AFTER SINGLE-LUNG TRANSPLANTATION
BIGGS, V. J., Dummer, S., Holsinger, F. C., Loyd, J. E., Christman, B. W., & Frist, W. H. (1994). SUCCESSFUL TREATMENT OF INVASIVE BRONCHIAL ASPERGILLOSIS AFTER SINGLE-LUNG TRANSPLANTATION. CLINICAL INFECTIOUS DISEASES, 18(1), 123-124.