Mark Holodniy

Professor of Medicine (Infectious Diseases) at the Palo Alto Veterans Affairs Health Care System

Professional Education

Residency: Good Samaritan Regional Medical Center (1988) AZ

Fellowship: Stanford University School of Medicine (1990) CA

Board Certification: Infectious Disease, American Board of Internal Medicine (1990)

Board Certification: Internal Medicine, American Board of Internal Medicine (1988)

Internship: Good Samaritan Regional Medical Center (1986) AZ

Medical Education: Northwestern Memorial Hospital (1985) IL

BS, Seattle University, Biology (1980)

---, Stanford University, Infectious Diseases Fellowship (1990)

Honors & Awards

Fellow, Infectious Disease Society of America (2005)

Divisional Award for Exceptional Contributions in Education in the Division of Infectious Disease, Department of Medicine (2004)

Infectious Diseases Teaching Award, Division of Infectious Diseases (2004)

HIV Program Clinical Excellence Award, Department of Veterans Affairs (2001)

Infectious Diseases Teaching Award, Division of Infectious Diseases (1997)

Fellow, American College of Physicians (1996)

Administrative Appointments

Member, Medical School Faculty Senate (1999 - 2002)

Co-Chairman, Administrative Panel on Biosafety (1995 - 2014)

Application of a non-amplification-based technology to detect invasive fungal pathogens
Hsu, J. L., Binkley, J., Clemons, K. V., Stevens, D. A., Nicolls, M. R., & Holodniy, M. (2014). Application of a non-amplification-based technology to detect invasive fungal pathogens. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 78(2), 137-140.

Acute and chronic immune biomarker changes during interferon/ribavirin treatment in HIV/HCV co-infected patients.
Jain, M. K., Adams-Huet, B., Terekhova, D., Kushner, L. E., Bedimo, R., & Holodniy, M. (2014). Acute and chronic immune biomarker changes during interferon/ribavirin treatment in HIV/HCV co-infected patients. Journal of viral hepatitis.

MicroRNA and hepatitis C virus- challenges in investigation and translation: a review of the literature.
Waldron, P. R., & Holodniy, M. (2014). MicroRNA and hepatitis C virus- challenges in investigation and translation: a review of the literature. Diagnostic microbiology and infectious disease.

The VACS Index Accurately Predicts Mortality and Treatment Response among Multi-Drug Resistant HIV Infected Patients Participating in the Options in Management with Antiretrovirals (OPTIMA) Study.
Brown, S. T., Tate, J. P., Kyriakides, T. C., Kirkwood, K. A., & Holodniy, M. (2014). The VACS Index Accurately Predicts Mortality and Treatment Response among Multi-Drug Resistant HIV Infected Patients Participating in the Options in Management with Antiretrovirals (OPTIMA) Study. PloS one, 9(3), e92606.

Human Pegivirus (HPgV or GB virus C) RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA containing particles are infectious in vitro.
Chivero, E. T., Bhattarai, N., Rydze, R. T., Winters, M. A., Holodniy, M., & Stapleton, J. (2014). Human Pegivirus (HPgV or GB virus C) RNA is found in multiple blood mononuclear cells in vivo and serum-derived viral RNA containing particles are infectious in vitro. The Journal of general virology.

Public Health Practice Is Not Research.
Otto, J. L., Holodniy, M., & Defraites, R. F. (2014). Public Health Practice Is Not Research. American journal of public health.

Cost-Effectiveness of Newer Antiretroviral Drugs in Treatment-Experienced Patients With Multidrug-Resistant HIV Disease.
Bayoumi, A. M., Barnett, P. G., Joyce, V. R., Griffin, S. C., Sun, H., & Owens, D. K. (2013). Cost-Effectiveness of Newer Antiretroviral Drugs in Treatment-Experienced Patients With Multidrug-Resistant HIV Disease. Journal of acquired immune deficiency syndromes , 64(4), 382-391.

Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster
Morrison, V. A., Oxman, M. N., Levin, M. J., Schmader, K. E., Guatelli, J. C., & Annunziato, P. W. (2013). Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster. JOURNAL OF INFECTIOUS DISEASES, 208(4), 559-563.

Concurrent outbreaks with co-infection of norovirus and Clostridium difficile in a long-term-care facility
Ludwig, A., Sato, K., Schirmer, P., Maniar, A., Lucero-Obusan, C., & Holodniy, M. (2013). Concurrent outbreaks with co-infection of norovirus and Clostridium difficile in a long-term-care facility. EPIDEMIOLOGY AND INFECTION, 141(8), 1598-1603.

Health-related Quality of Life Assessment after Antiretroviral Therapy: A Review of the Literature.
Gakhar, H., Kamali, A., & Holodniy, M. (2013). Health-related Quality of Life Assessment after Antiretroviral Therapy: A Review of the Literature. Drugs, 73(7), 651-672.

Immune Biomarker Differences and Changes Comparing HCV Mono-Infected, HIV/HCV Co-Infected, and HCV Spontaneously Cleared Patients
Kushner, L. E., Wendelboe, A. M., Lazzeroni, L. C., Chary, A., Winters, M. A., & Holodniy, M. (2013). Immune Biomarker Differences and Changes Comparing HCV Mono-Infected, HIV/HCV Co-Infected, and HCV Spontaneously Cleared Patients. PLOS ONE, 8(4).

Cost-Effectiveness Analysis of Risk-Factor Guided and Birth-Cohort Screening for Chronic Hepatitis C Infection in the United States
Liu, S., Cipriano, L. E., Holodniy, M., & Goldhaber-Fiebert, J. D. (2013). Cost-Effectiveness Analysis of Risk-Factor Guided and Birth-Cohort Screening for Chronic Hepatitis C Infection in the United States. PLOS ONE, 8(3).

Dengue Surveillance in Veterans Affairs Healthcare Facilities, 2007-2010
Schirmer, P. L., Lucero-Obusan, C. A., Benoit, S. R., Santiago, L. M., Stanek, D., & Holodniy, M. (2013). Dengue Surveillance in Veterans Affairs Healthcare Facilities, 2007-2010. PLOS NEGLECTED TROPICAL DISEASES, 7(3).

Combining Surveillance Systems: Effective Merging of U.S. Veteran and Military Health Data.
Pavlin, J. A., Burkom, H. S., Elbert, Y., Lucero-Obusan, C., Winston, C. A., & Holodniy, M. (2013). Combining Surveillance Systems: Effective Merging of U.S. Veteran and Military Health Data. PloS one, 8(12), e84077.

Risk of cardiovascular disease from antiretroviral therapy for HIV: a systematic review.
Bavinger, C., Bendavid, E., Niehaus, K., Olshen, R. A., Olkin, I., & Desai, M. (2013). Risk of cardiovascular disease from antiretroviral therapy for HIV: a systematic review. PloS one, 8(3).

Immune biomarker differences and changes comparing HCV mono-infected, HIV/HCV co-infected, and HCV spontaneously cleared patients.
Kushner, L. E., Wendelboe, A. M., Lazzeroni, L. C., Chary, A., Winters, M. A., & Holodniy, M. (2013). Immune biomarker differences and changes comparing HCV mono-infected, HIV/HCV co-infected, and HCV spontaneously cleared patients. PloS one, 8(4).

Influenza treatment and prophylaxis with neuraminidase inhibitors: a review.
Kamali, A., & Holodniy, M. (2013). Influenza treatment and prophylaxis with neuraminidase inhibitors: a review. Infection and drug resistance, 6, 187-198.

CD4 Counts and Mortality in Virologically Suppressed US Veterans.
Drechsler, H., Zhang, S., Holodniy, M., & Bedimo, R. (2013). CD4 Counts and Mortality in Virologically Suppressed US Veterans. Journal of the International Association of Providers of AIDS Care.

GBV-C viremia and clinical events in advanced HIV infection.
Sahni, H., Kirkwood, K., Kyriakides, T. C., Stapleton, J., & Brown, S. T. (2013). GBV-C viremia and clinical events in advanced HIV infection. Journal of medical virology.

IL28B polymorphism is not associated with HCV protease diversity in patients co-infected with HIV and HCV treated with pegylated interferon and ribavirin
Osinusi, A., Chary, A., Winters, M. A., Naggie, S., Masur, H., & Holodniy, M. (2012). IL28B polymorphism is not associated with HCV protease diversity in patients co-infected with HIV and HCV treated with pegylated interferon and ribavirin. JOURNAL OF MEDICAL VIROLOGY, 84(10), 1522-1527.

Cost Effectiveness of Screening Strategies for Early Identification of HIV and HCV Infection in Injection Drug Users
Cipriano, L. E., Zaric, G. S., Holodniy, M., Bendavid, E., Owens, D. K., & Brandeau, M. L. (2012). Cost Effectiveness of Screening Strategies for Early Identification of HIV and HCV Infection in Injection Drug Users. PLOS ONE, 7(9).

Development of Elvitegravir Resistance and Linkage of Integrase Inhibitor Mutations with Protease and Reverse Transcriptase Resistance Mutations
Winters, M. A., Lloyd, R. M., Shafer, R. W., Kozal, M. J., Miller, M. D., & Holodniy, M. (2012). Development of Elvitegravir Resistance and Linkage of Integrase Inhibitor Mutations with Protease and Reverse Transcriptase Resistance Mutations. PLOS ONE, 7(7).

Predictive value of HIV-1 replication capacity and phenotypic susceptibility scores in antiretroviral treatment-experienced patients
Bedimo, R., Kyriakides, T., Brown, S., Weidler, J., Lie, Y., & Holodniy, M. (2012). Predictive value of HIV-1 replication capacity and phenotypic susceptibility scores in antiretroviral treatment-experienced patients. HIV MEDICINE, 13(6), 345-351.

Results from a Large-Scale Epidemiologic Look-Back Investigation of Improperly Reprocessed Endoscopy Equipment
Holodniy, M., Oda, G., Schirmer, P. L., Lucero, C. A., Khudyakov, Y. E., & Cross, G. M. (2012). Results from a Large-Scale Epidemiologic Look-Back Investigation of Improperly Reprocessed Endoscopy Equipment. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 33(7), 649-656.

Comparative Assessment of Antimicrobial Usage Measures in the Department of Veterans Affairs
Schirmer, P. L., Mercier, R. C., Ryono, R. A., Nguyen, N., Lucero, C. A., & Holodniy, M. (2012). Comparative Assessment of Antimicrobial Usage Measures in the Department of Veterans Affairs. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 33(4), 409-411.

Outcomes Associated with a Cognitive-Behavioral Chronic Pain Management Program Implemented in Three Public HIV Primary Care Clinics
Trafton, J. A., Sorrell, J. T., Holodniy, M., Pierson, H., Link, P., & Israelski, D. (2012). Outcomes Associated with a Cognitive-Behavioral Chronic Pain Management Program Implemented in Three Public HIV Primary Care Clinics. JOURNAL OF BEHAVIORAL HEALTH SERVICES & RESEARCH, 39(2), 158-173.

Quantitation of hepatitis C virus RNA in peripheral blood mononuclear cells in HCV-monoinfection and HIV/HCV-coinfection
Chary, A., Winters, M. A., Eisen, R., Knight, T. H., Asmuth, D. M., & Holodniy, M. (2012). Quantitation of hepatitis C virus RNA in peripheral blood mononuclear cells in HCV-monoinfection and HIV/HCV-coinfection. JOURNAL OF MEDICAL VIROLOGY, 84(3), 431-437.

New Protease Inhibitors for the Treatment of Chronic Hepatitis C A Cost-Effectiveness Analysis
Liu, S., Cipriano, L. E., Holodniy, M., Owens, D. K., & Goldhaber-Fiebert, J. D. (2012). New Protease Inhibitors for the Treatment of Chronic Hepatitis C A Cost-Effectiveness Analysis. ANNALS OF INTERNAL MEDICINE, 156(4), 279-U68.

Ultrasensitive detection of rare mutations using next-generation targeted resequencing
Flaherty, P., Natsoulis, G., Muralidharan, O., Winters, M., Buenrostro, J., & Ji, H. P. (2012). Ultrasensitive detection of rare mutations using next-generation targeted resequencing. NUCLEIC ACIDS RESEARCH, 40(1).

Effect of Treatment Interruption and Intensification of Antiretroviral Therapy on Health-Related Quality of Life in Patients with Advanced HIV: A Randomized, Controlled Trial
Joyce, V. R., Barnett, P. G., Chow, A., Bayoumi, A. M., Griffin, S. C., & Owens, D. K. (2012). Effect of Treatment Interruption and Intensification of Antiretroviral Therapy on Health-Related Quality of Life in Patients with Advanced HIV: A Randomized, Controlled Trial. MEDICAL DECISION MAKING, 32(1), 70-82.

HIV-HBV vaccine escape mutant infection with loss of HBV surface antibody and persistent HBV viremia on tenofovir/emtricitabine without antiviral resistance
Schirmer, P., Winters, M., & Holodniy, M. (2011). HIV-HBV vaccine escape mutant infection with loss of HBV surface antibody and persistent HBV viremia on tenofovir/emtricitabine without antiviral resistance. JOURNAL OF CLINICAL VIROLOGY, 52(3), 261-264.

Use of dried clinical samples for storing and detecting influenza RNA
Winters, M., Lloyd, R., Shahidi, A., Brown, S., & Holodniy, M. (2011). Use of dried clinical samples for storing and detecting influenza RNA. INFLUENZA AND OTHER RESPIRATORY VIRUSES, 5(6), 413-417.

Diagnosing invasive fungal disease in critically ill patients
Hsu, J. L., Ruoss, S. J., Bower, N. D., Lin, M., Holodniy, M., & Stevens, D. A. (2011). Diagnosing invasive fungal disease in critically ill patients. CRITICAL REVIEWS IN MICROBIOLOGY, 37(4), 277-312.

IL28B POLYMORPHISM IS NOT ASSOCIATED WITH HCV PROTEASE DIVERSITY IN HIV/HCV-COINFECTED PATIENTS TREATED WITH AN INTERFERON-BASED REGIMEN
Osinusi, A., Chary, A., Kottilil, S., Winters, M. A., Naggie, S., & Holodniy, M. (2011). IL28B POLYMORPHISM IS NOT ASSOCIATED WITH HCV PROTEASE DIVERSITY IN HIV/HCV-COINFECTED PATIENTS TREATED WITH AN INTERFERON-BASED REGIMEN. HEPATOLOGY, 54, 815A-815A.

Enhanced health event detection and influenza surveillance using a joint Veterans Affairs and Department of Defense biosurveillance application
Lucero, C. A., Oda, G., Cox, K., Maldonado, F., Lombardo, J., & Holodniy, M. (2011). Enhanced health event detection and influenza surveillance using a joint Veterans Affairs and Department of Defense biosurveillance application. BMC MEDICAL INFORMATICS AND DECISION MAKING, 11.

Determinants of the Cost of Health Services Used by Veterans With HIV
Barnett, P. G., Chow, A., Joyce, V. R., Bayoumi, A. M., Griffin, S. C., & Owens, D. K. (2011). Determinants of the Cost of Health Services Used by Veterans With HIV. MEDICAL CARE, 49(9), 848-856.

Interferon combination therapy for HIV/hepatitis C virus coinfection
Chary, A., & Holodniy, M. (2011). Interferon combination therapy for HIV/hepatitis C virus coinfection. IMMUNOTHERAPY, 3(9), 1087-1102.

One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System
Hsu, J. L., Siroka, A. M., Smith, M. W., Holodniy, M., & Meduri, G. U. (2011). One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 15(6), E382-E387.

Clinically Significant Drug Interactions in Younger and Older Human Immunodeficiency Virus-Positive Patients Receiving Antiretroviral Therapy
Yiu, P., Nguyen, N. N., & Holodniy, M. (2011). Clinically Significant Drug Interactions in Younger and Older Human Immunodeficiency Virus-Positive Patients Receiving Antiretroviral Therapy. PHARMACOTHERAPY, 31(5), 480-489.

Results of Antiretroviral Treatment Interruption and Intensification in Advanced Multi-Drug Resistant HIV Infection from the OPTIMA Trial
Holodniy, M., Brown, S. T., Cameron, D. W., Kyriakides, T. C., Angus, B., & Darbyshire, J. (2011). Results of Antiretroviral Treatment Interruption and Intensification in Advanced Multi-Drug Resistant HIV Infection from the OPTIMA Trial. PLOS ONE, 6(3).

Integrating Tobacco Cessation Into Mental Health Care for Posttraumatic Stress Disorder A Randomized Controlled Trial
McFall, M., Saxon, A. J., Malte, C. A., Chow, B., Bailey, S., & Lavori, P. W. (2010). Integrating Tobacco Cessation Into Mental Health Care for Posttraumatic Stress Disorder A Randomized Controlled Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 304(22), 2485-2493.

Comparative effectiveness of dried plasma HIV-1 viral load testing in Brazil using ViveST for sample collection
Zanoni, M., Cortes, R., Diaz, R. S., Sucupira, M. C., Ferreira, D., & Holodniy, M. (2010). Comparative effectiveness of dried plasma HIV-1 viral load testing in Brazil using ViveST for sample collection. JOURNAL OF CLINICAL VIROLOGY, 49(4), 245-248.

Effect of Home Testing of International Normalized Ratio on Clinical Events.
Matchar, D. B., Jacobson, A., Dolor, R., Edson, R., Uyeda, L., & Lavori, P. (2010). Effect of Home Testing of International Normalized Ratio on Clinical Events. NEW ENGLAND JOURNAL OF MEDICINE, 363(17), 1608-1620.

An evaluation of patient self-testing competency of prothrombin time for managing anticoagulation: pre-randomization results of VA Cooperative Study #481-The Home INR Study (THINRS)
Dolor, R. J., Ruybalid, R. L., Uyeda, L., Edson, R. G., Phibbs, C., & Matchar, D. B. (2010). An evaluation of patient self-testing competency of prothrombin time for managing anticoagulation: pre-randomization results of VA Cooperative Study #481-The Home INR Study (THINRS). JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 30(3), 263-275.

Maternal-Fetal Pharmacokinetics and Dynamics of a Single Intrapartum Dose of Maraviroc in Rhesus Macaques
Winters, M. A., Van Rompay, K. Ka., Kashuba, A. Dm., Shulman, N. S., & Holodniy, M. (2010). Maternal-Fetal Pharmacokinetics and Dynamics of a Single Intrapartum Dose of Maraviroc in Rhesus Macaques. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54(10), 4059-4063.

Impact of Interferon-Ribavirin Treatment on Hepatitis C Virus (HCV) Protease Quasispecies Diversity in HIV- and HCV-Coinfected Patients
Chary, A., Winters, M. A., Kottilil, S., Murphy, A. A., Polis, M. A., & Holodniy, M. (2010). Impact of Interferon-Ribavirin Treatment on Hepatitis C Virus (HCV) Protease Quasispecies Diversity in HIV- and HCV-Coinfected Patients. JOURNAL OF INFECTIOUS DISEASES, 202(6), 889-893.

Effect of a Zoster Vaccine on Herpes Zoster-Related Interference with Functional Status and Health-Related Quality-of-Life Measures in Older Adults
Schmader, K. E., Johnson, G. R., Saddier, P., Ciarleglio, M., Wang, W. Wb., & Oxman, M. N. (2010). Effect of a Zoster Vaccine on Herpes Zoster-Related Interference with Functional Status and Health-Related Quality-of-Life Measures in Older Adults. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(9), 1634-1641.

Recent advances in hepatitis C virus treatment: review of HCV protease inhibitor clinical trials.
Chary, A., & Holodniy, M. (2010). Recent advances in hepatitis C virus treatment: review of HCV protease inhibitor clinical trials. Reviews on recent clinical trials, 5(3), 158-173.

Is spinal tuberculosis contagious?
Schirmer, P., Renault, C. A., & Holodniy, M. (2010). Is spinal tuberculosis contagious?. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 14(8), E659-E666.

Connection Domain Mutations in Treatment-Experienced Patients in the OPTIMA Trial
Dau, B., Ayers, D., Singer, J., Harrigan, P. R., Brown, S., & Holodniy, M. (2010). Connection Domain Mutations in Treatment-Experienced Patients in the OPTIMA Trial. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 54(2), 160-166.

Impact of Highly Active Antiretroviral Therapy on Hepatitis C Virus Protease Quasispecies Diversity in HIV Co-Infected Patients
Winters, M. A., Chary, A., Eison, R., Asmuth, D., & Holodniy, M. (2010). Impact of Highly Active Antiretroviral Therapy on Hepatitis C Virus Protease Quasispecies Diversity in HIV Co-Infected Patients. JOURNAL OF MEDICAL VIROLOGY, 82(5), 791-798.

Effective Detection of the 2009 H1N1 Influenza Pandemic in US Veterans Affairs Medical Centers Using a National Electronic Biosurveillance System
Schirmer, P., Lucero, C., Oda, G., Lopez, J., & Holodniy, M. (2010). Effective Detection of the 2009 H1N1 Influenza Pandemic in US Veterans Affairs Medical Centers Using a National Electronic Biosurveillance System. PLOS ONE, 5(3).

Structured interruptions of highly active antiretroviral therapy in cycles of 4 weeks off/12 weeks on therapy in children having a chronically undetectable viral load cause progressively smaller viral rebounds
Palacios, G. C., Sanchez, L. M., Briones, E., Ramirez, T. J., Castillo, H., & Holodniy, M. (2010). Structured interruptions of highly active antiretroviral therapy in cycles of 4 weeks off/12 weeks on therapy in children having a chronically undetectable viral load cause progressively smaller viral rebounds. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 14(1), E34-E40.

Sudden sensorineural hearing loss associated with vardenafil.
Snodgrass, A. J., Campbell, H. M., Mace, D. L., Faria, V. L., Swanson, K. M., & Holodniy, M. (2010). Sudden sensorineural hearing loss associated with vardenafil. Pharmacotherapy, 30(1), 112-?.

Varicella-Zoster Virus-Specific Immune Responses to Herpes Zoster in Elderly Participants in a Trial of a Clinically Effective Zoster Vaccine
Weinberg, A., Zhang, J. H., Oxman, M. N., Johnson, G. R., Hayward, A. R., & Levin, M. J. (2009). Varicella-Zoster Virus-Specific Immune Responses to Herpes Zoster in Elderly Participants in a Trial of a Clinically Effective Zoster Vaccine. JOURNAL OF INFECTIOUS DISEASES, 200(7), 1068-1077.

The concurrent validity and responsiveness of the health utilities index (HUI 3) among patients with advanced HIV/AIDS
Nosyk, B., Sun, H., Bansback, N., Guh, D. P., Li, X., & Anis, A. H. (2009). The concurrent validity and responsiveness of the health utilities index (HUI 3) among patients with advanced HIV/AIDS. QUALITY OF LIFE RESEARCH, 18(7), 815-824.

Quality of Life of Patients With Advanced HIV/AIDS: Measuring the Impact of Both AIDS-Defining Events and Non-AIDS Serious Adverse Events
Anis, A. H., Nosyk, B., Sun, H., Guh, D. P., Bansback, N., & Brown, S. T. (2009). Quality of Life of Patients With Advanced HIV/AIDS: Measuring the Impact of Both AIDS-Defining Events and Non-AIDS Serious Adverse Events. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 51(5), 631-639.

Thrombocytopenia from Combination Treatment with Oseltamivir and Probenecid: Case Report, MedWatch Data Summary, and Review of the Literature
Raisch, D. W., Straight, T. M., & Holodniy, M. (2009). Thrombocytopenia from Combination Treatment with Oseltamivir and Probenecid: Case Report, MedWatch Data Summary, and Review of the Literature. PHARMACOTHERAPY, 29(8), 988-992.

A Real-Time PCR Assay to Identify and Discriminate Among Wild-Type and Vaccine Strains of Varicella-Zoster Virus and Herpes Simplex Virus in Clinical Specimens, and Comparison With the Clinical Diagnoses
Harbecke, R., Oxman, M. N., Arnold, B. A., Ip, C., Johnson, G. R., & Keller, P. M. (2009). A Real-Time PCR Assay to Identify and Discriminate Among Wild-Type and Vaccine Strains of Varicella-Zoster Virus and Herpes Simplex Virus in Clinical Specimens, and Comparison With the Clinical Diagnoses. JOURNAL OF MEDICAL VIROLOGY, 81(7), 1310-1322.

Effect of the MTHFR C677T and A1298C Polymorphisms on Survival in Patients With Advanced CKD and ESRD: A Prospective Study
Jamison, R. L., Shih, M.-C., Humphries, D. E., Guarino, P. D., Kaufman, J. S., & Lavori, P. (2009). Effect of the MTHFR C677T and A1298C Polymorphisms on Survival in Patients With Advanced CKD and ESRD: A Prospective Study. AMERICAN JOURNAL OF KIDNEY DISEASES, 53(5), 779-789.

Oseltamivir for treatment and prophylaxis of influenza infection
Schirmer, P., & Holodniy, M. (2009). Oseltamivir for treatment and prophylaxis of influenza infection. EXPERT OPINION ON DRUG SAFETY, 8(3), 357-371.

Dried-Plasma Transport Using a Novel Matrix and Collection System for Human Immunodeficiency Virus and Hepatitis C Virus Virologic Testing
Lloyd, R. M., Burns, D. A., Huong, J. T., Mathis, R. L., Winters, M. A., & Holodniy, M. (2009). Dried-Plasma Transport Using a Novel Matrix and Collection System for Human Immunodeficiency Virus and Hepatitis C Virus Virologic Testing. JOURNAL OF CLINICAL MICROBIOLOGY, 47(5), 1491-1496.

Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease
Joyce, V., Barnett PG, Bayoumi A, Griffin SC, Kyriakides TC, & Cameron W. (2009). Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease. Journal of Acquired Immune Deficiency Syndromes, 50(1).

Infectious complications in OIF/OEF veterans with traumatic brain injury
Dau, B., Oda, G., & Holodniy, M. (2009). Infectious complications in OIF/OEF veterans with traumatic brain injury. JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT, 46(6), 673-684.

Novel Targets for Antiretroviral Therapy Clinical Progress to Date
Dau, B., & Holodniy, M. (2009). Novel Targets for Antiretroviral Therapy Clinical Progress to Date. DRUGS, 69(1), 31-50.

Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease
Joyce, V. R., Barnett, P. G., Bayoumi, A. M., Griffin, S. C., Kyriakides, T. C., & Owens, D. K. (2009). Health-Related Quality of Life in a Randomized Trial of Antiretroviral Therapy for Advanced HIV Disease. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 50(1), 27-36.

Pharmacokinetics and tolerability of oseltamivir combined with probenecid
Holodniy, M., Penzak, S. R., Straight, T. M., Davey, R. T., Lee, K. K., & Deyton, L. R. (2008). Pharmacokinetics and tolerability of oseltamivir combined with probenecid. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 52(9), 3013-3021.

The Relationship Between HIV Infection and Cardiovascular Disease.
Dau, B., & Holodniy, M. (2008). The Relationship Between HIV Infection and Cardiovascular Disease. Current cardiology reviews, 4(3), 203-218.

Cost-effectiveness of HIV screening in patients older than 55 years of age
Sanders, G. D., Bayoumi, A. M., Holodnly, M., & Owens, D. K. (2008). Cost-effectiveness of HIV screening in patients older than 55 years of age. ANNALS OF INTERNAL MEDICINE, 148(12), 889-?.

Frequency of HIV screening in the Veterans Health Administration: Implications for early diagnosis of HIV infection
Valdiserri, R. O., Rodriguez, F., & Holodruy, M. (2008). Frequency of HIV screening in the Veterans Health Administration: Implications for early diagnosis of HIV infection. AIDS EDUCATION AND PREVENTION, 20(3), 258-264.

Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine
Levin, M. J., Oxman, M. N., Zhang, J. H., Johnson, G. R., Stanley, H., & Weinberg, A. (2008). Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine. JOURNAL OF INFECTIOUS DISEASES, 197(6), 825-835.

Safety, tolerability, pharmacokinetics, and efficacy of an interleukin-2 agonist among HIV-infected patients receiving highly active antiretroviral therapy
Davey, R. T., Pertel, P. E., Benson, A., Cassell, D. J., Gazzard, B. G., & Choudhri, S. (2008). Safety, tolerability, pharmacokinetics, and efficacy of an interleukin-2 agonist among HIV-infected patients receiving highly active antiretroviral therapy. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 28(2), 89-100.

Severe pneumonia due to adenovirus serotype 14: A new respiratory threat?
Louie, J. K., Kajon, A. E., Holodniy, M., Guardia-LaBar, L., Lee, B., & Schnurr, D. P. (2008). Severe pneumonia due to adenovirus serotype 14: A new respiratory threat?. CLINICAL INFECTIOUS DISEASES, 46(3), 421-425.

HIV infection in the elderly
Nguyen N, & Holodniy M. (2008). HIV infection in the elderly. Clinical Interventions in Aging, 3(4).

Prevalence of HIV infection among inpatients and outpatients in department of veterans affairs health care systems: Implications for screening programs for HIV
Owens, D. K., Sundaram, V., Lazzeroni, L. C., Douglass, L. R., Sanders, G. D., & Holodniy, M. (2007). Prevalence of HIV infection among inpatients and outpatients in department of veterans affairs health care systems: Implications for screening programs for HIV. AMERICAN JOURNAL OF PUBLIC HEALTH, 97(12), 2173-2178.

A systematic review of cost-utility analyses in HIV/AIDS: Implications for public policy
Hornberger, J., Holodniy, M., Robertus, K., Winnike, M., Gibson, E., & Verhulst, E. (2007). A systematic review of cost-utility analyses in HIV/AIDS: Implications for public policy. MEDICAL DECISION MAKING, 27(6), 789-821.

Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: An OPTIMA trial substudy
Desai, S., Kyriakides, T., Holodniy, M., Al-Salman, J., Griffith, B., & Kozal, M. (2007). Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: An OPTIMA trial substudy. HIV CLINICAL TRIALS, 8(5), 293-302.

HIV testing of at risk patients in a large integrated health care system
Owens, D. K., Sundaram, V., Lazzeroni, L. C., Douglass, L. R., Tempio, P., & Bozzette, S. A. (2007). HIV testing of at risk patients in a large integrated health care system. JOURNAL OF GENERAL INTERNAL MEDICINE, 22(3), 315-320.

Role of Environmental Surveillance in Dtermining the Risk of Hospital-Acquired Legionellosis: A National Surveillance Study With Clinical Correlations
Stout, Je., Muder RR, Mietzner S, Wagener MM, Perri MB, & Yu VL. (2007). Role of Environmental Surveillance in Dtermining the Risk of Hospital-Acquired Legionellosis: A National Surveillance Study With Clinical Correlations. Infection Control and Hospital Epidemiology, 28(7).

Representational Fluency in HIV Clinical Practice: A Model of Instructor Discourse
Banach, Ma., Gifford, BR, & Holodniy M. (2007). Representational Fluency in HIV Clinical Practice: A Model of Instructor Discourse. Journal of Continuing Education in the Health Professions, 27(3).

Darunavir in the treatment of HIV-1 infection - Viewpoint
Holodniy, M. (2007). Darunavir in the treatment of HIV-1 infection - Viewpoint. DRUGS, 67(18), 2803-2803.

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters
Liu, Z., Winters, M., Holodniy, M., & Dai, H. (2007). siRNA delivery into human T cells and primary cells with carbon-nanotube transporters. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(12), 2023-2027.

Relationship between antiretroviral prescribing patterns and treatment guidelines in treatment-naive HIV-1-infected US veterans (1992-2004)
Holodniy, M., Hornberger, J., Rapoport, D., Robertus, K., MaCurdy, T. E., & Deyton, L. (2007). Relationship between antiretroviral prescribing patterns and treatment guidelines in treatment-naive HIV-1-infected US veterans (1992-2004). JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 44(1), 20-29.

HIV-1 load quantitation: A 17-year perspective
Holodniy, M. (2006). HIV-1 load quantitation: A 17-year perspective. JOURNAL OF INFECTIOUS DISEASES, 194, S38-S44.

Prevention of shingles by varicella zoster virus vaccination
Holodniy, M. (2006). Prevention of shingles by varicella zoster virus vaccination. EXPERT REVIEW OF VACCINES, 5(4), 431-443.

Hepatitis C virus protease gene diversity in patients coinfected with human immunodeficiency virus
Winters, M. A., Welles, S. L., & Holodniy, M. (2006). Hepatitis C virus protease gene diversity in patients coinfected with human immunodeficiency virus. JOURNAL OF VIROLOGY, 80(8), 4196-4199.

The effect of diagnosis with HIV infection on health-related quality of life
Honiden, S., Sundaram, V., Nease, R. F., Holodniy, M., Lazzeroni, L. C., & Owens, D. K. (2006). The effect of diagnosis with HIV infection on health-related quality of life. QUALITY OF LIFE RESEARCH, 15(1), 69-82.

Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: an OPTIMA trial substudy
Desai, S. S., Kyriakides, T. C., Holodniy, M., Al-Salman, J., Griffith, B. P., & Kozal, M. J. (2006). Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: an OPTIMA trial substudy. ANTIVIRAL THERAPY, 11(5), S184-S184.

The safety and tolerability of Z-100 in patients infected with HIV-1
Borucki M, Holodniy M, Pierone G, Ruane P, Steinhart C, & Pollard RB. (2006). The safety and tolerability of Z-100 in patients infected with HIV-1. Antiviral Therapy, 11.

Utilization and access to Antiretroviral genotypic resistance testing and results within the US department of veterans affairs
Goetz, M. B., Holodniy, M., Poulton, J. S., Rodriguez, F. H., & Rigsby, M. O. (2006). Utilization and access to Antiretroviral genotypic resistance testing and results within the US department of veterans affairs. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 41(1), 59-62.

Case files from Stanford University Medical Center: the initial presentation of HIV-1 infection--where public and personal health meet.
Liu, M., Holodniy, M., Zolopa, A. R., & Shafer, R. W. (2006). Case files from Stanford University Medical Center: the initial presentation of HIV-1 infection--where public and personal health meet. MedGenMed : Medscape general medicine, 8(1), 24-?.

Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: An international comparison (The GUESS Study)
Zolopa, A. R., Lazzeroni, L. C., Rinehart, A., Vezinet, F. B., Clavel, F., & Kuritzkes, D. R. (2005). Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: An international comparison (The GUESS Study). CLINICAL INFECTIOUS DISEASES, 41(1), 92-99.

A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults
Oxman, M. N., Levin, M. J., Johnson, G. R., Schmader, K. E., Straus, S. E., & Silber, J. L. (2005). A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults. NEW ENGLAND JOURNAL OF MEDICINE, 352(22), 2271-2284.

Proteomic analysis of serum cytokine levels in response to highly active antiretroviral therapy (HAART)
Relucio, K. I., Beernink, H. T., Chen, D., Israelski, D. M., Kim, R., & Holodniy, M. (2005). Proteomic analysis of serum cytokine levels in response to highly active antiretroviral therapy (HAART). JOURNAL OF PROTEOME RESEARCH, 4(2), 227-231.

Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy
Sanders, G. D., Bayoumi, A. M., Sundaram, V., Bilir, S. P., Neukermans, C. P., & Owens, D. K. (2005). Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy. NEW ENGLAND JOURNAL OF MEDICINE, 352(6), 570-585.

Clinical utility of viral load measurements in individuals with chronic hepatitis C infection on antiviral therapy.
Terrault, Na., Pawlotsky JM, McHutchison J, Anderson F, Krajden M, & Friesenhahn M. (2005). Clinical utility of viral load measurements in individuals with chronic hepatitis C infection on antiviral therapy. Journal of Viral Hepatitis, 12(5).

Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy
Sanders GD, Bayoumi AM, Sundaram V, Bilir SP, Neukermans CP, & Owens DK. (2005). Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy. New England Journal of Medicine, 352(6).

Prevalence of antiretroviral drug resistance in the HIV-1-infected urban indigent population in San Francisco: a representative study
Holodniy, M., Charlebois, E. D., Bangsberg, D. R., Zolopa, A. R., Schulte, M., & Moss, A. R. (2004). Prevalence of antiretroviral drug resistance in the HIV-1-infected urban indigent population in San Francisco: a representative study. INTERNATIONAL JOURNAL OF STD & AIDS, 15(8), 543-551.

Multicenter evaluation of the performance characteristics of the Bayer VERSANT HCV RNA 3.0 assay (bDNA)
Elbeik, T., Surtihadi, J., Destree, M., Gorlin, J., Holodniy, M., & Terrault, N. A. (2004). Multicenter evaluation of the performance characteristics of the Bayer VERSANT HCV RNA 3.0 assay (bDNA). JOURNAL OF CLINICAL MICROBIOLOGY, 42(2), 563-569.

Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4
Chang, T. Ly., Chang, C. H., Simpson, D. A., Xu, Q., Martin, P. K., & Lee, P. P. (2003). Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(20), 11672-11677.

High levels of adherence do not prevent accumulation of HIV drug resistance mutations
Bangsberg, D. R., Charlebois, E. D., Grant, R. M., Holodniy, M., Deeks, S. G., & Moss, A. (2003). High levels of adherence do not prevent accumulation of HIV drug resistance mutations. AIDS, 17(13), 1925-1932.

An open-label randomized clinical trial of novel therapeutic strategies for HIV-infected patients in whom antiretroviral therapy has failed: rationale and design of the OPTIMA Trial
Kyriakides, T. C., Babiker, A., Singer, J., Cameron, W., Schechter, M. T., & Gazzard, B. (2003). An open-label randomized clinical trial of novel therapeutic strategies for HIV-infected patients in whom antiretroviral therapy has failed: rationale and design of the OPTIMA Trial. CONTROLLED CLINICAL TRIALS, 24(4), 481-500.

Successful management of disseminated Nocardia transvalensis infection in a heart transplant recipient after development of sulfonamide resistance: Case report and review
Lopez, F. A., Johnson, F., Novosad, D. M., Beaman, B. L., & Holodniy, M. (2003). Successful management of disseminated Nocardia transvalensis infection in a heart transplant recipient after development of sulfonamide resistance: Case report and review. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 22(4), 492-497.

Accuracy of the TRUGENE HIV-1 genotyping kit
Grant, R. M., Kuritzkes, D. R., JOHNSON, V. A., Mellors, J. W., Sullivan, J. L., & Winslow, D. L. (2003). Accuracy of the TRUGENE HIV-1 genotyping kit. JOURNAL OF CLINICAL MICROBIOLOGY, 41(4), 1586-1593.

Impact of highly active antiretroviral therapy and immunologic status on hepatitis C virus quasispecies diversity in human immunodeficiency virus/hepatitis C virus-coinfected patients
Babik, J. M., & Holodniy, M. (2003). Impact of highly active antiretroviral therapy and immunologic status on hepatitis C virus quasispecies diversity in human immunodeficiency virus/hepatitis C virus-coinfected patients. JOURNAL OF VIROLOGY, 77(3), 1940-1950.

Role of Deoxyribonucleoside Kinases and Deoxyribonucleotide Pool Alterations in Nucleoside Reverse Transcriptase Inhibitor Induced Mitochondrial Toxicity
Relucio K, & Holodniy M. (2003). Role of Deoxyribonucleoside Kinases and Deoxyribonucleotide Pool Alterations in Nucleoside Reverse Transcriptase Inhibitor Induced Mitochondrial Toxicity. Curr. Med. Chem. - Anti-Infective Agents.

HIV-1 RNA and viral load
Relucio, K., & Holodniy, M. (2002). HIV-1 RNA and viral load. CLINICS IN LABORATORY MEDICINE, 22(3), 593-?.

A pilot trial of indinavir, ritonavir, didanosine, and lamivudine in a once-daily four-drug regimen for HIV infection
Mole, L., Schmidgall, D., & Holodniy, Y. (2001). A pilot trial of indinavir, ritonavir, didanosine, and lamivudine in a once-daily four-drug regimen for HIV infection. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 27(3), 260-265.

Multinodular polymyositis in a patient with human immunodeficiency and hepatitis C virus coinfection
Richardson, S. J., LOPEZ, F., Rojas, S., Cho, S. H., Holodniy, M., & Katz, J. (2001). Multinodular polymyositis in a patient with human immunodeficiency and hepatitis C virus coinfection. MUSCLE & NERVE, 24(3), 433-437.

HIV resistance testing--has it come of age?
Holodniy, M. (2000). HIV resistance testing--has it come of age?. AIDS reader, 10(8), 474-475.

Assessment of developmental toxicity of antiretroviral drugs using a rat whole embryo culture system
Fujinaga, M., Schulte, M., & Holodniy, M. (2000). Assessment of developmental toxicity of antiretroviral drugs using a rat whole embryo culture system. TERATOLOGY, 62(2), 108-114.

Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population
Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Zolopa, A. R., Holodniy, M., & Moss, A. (2000). Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. AIDS, 14(4), 357-366.

Stability of plasma human immunodeficiency virus load in VACUTAINER PPT plasma preparation tubes during overnight shipment
Holodniy, M., Rainen, L., Herman, S., & Yen-Lieberman, B. (2000). Stability of plasma human immunodeficiency virus load in VACUTAINER PPT plasma preparation tubes during overnight shipment. JOURNAL OF CLINICAL MICROBIOLOGY, 38(1), 323-326.

A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS
Holodniy, M., KOCH, J., Mistal, M., Schmidt, J. M., Khandwala, A., & Porter, S. B. (1999). A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS. AMERICAN JOURNAL OF GASTROENTEROLOGY, 94(11), 3267-3273.

Decreased medical expenditures for care of HIV-seropositive patients - The impact of highly active antiretroviral therapy at a US Veterans Affairs Medical Center
Mole, L., Ockrim, K., & Holodniy, M. (1999). Decreased medical expenditures for care of HIV-seropositive patients - The impact of highly active antiretroviral therapy at a US Veterans Affairs Medical Center. PHARMACOECONOMICS, 16(3), 307-315.

Viral Load Monitoring in HIV Infection.
Holodniy, M. (1999). Viral Load Monitoring in HIV Infection. Current infectious disease reports, 1(5), 497-503.

Effects of collection, processing, and storage on RNA detection and quantification.
Holodniy, M. (1999). Effects of collection, processing, and storage on RNA detection and quantification. Methods in molecular medicine, 26, 43-59.

Controversies in AIDS treatment. Proceedings from CME conference sponsored by Cornell University Medical College and the American Foundation for AIDS Research (AmFAR). November 8, 1997. Faculty roundtable discussion.
Frost, K. R., Bellman, P., Cohen, C. J., Currier, J., Dobkin, J., & Vaughn, A. (1998). Controversies in AIDS treatment. Proceedings from CME conference sponsored by Cornell University Medical College and the American Foundation for AIDS Research (AmFAR). November 8, 1997. Faculty roundtable discussion. AIDS patient care and STDs, 12(7), 543-555.

Controversies in AIDS treatment. Proceedings from CME conference sponsored by Cornell University Medical College and the American Foundation for AIDS Research (AmFAR). November 8, 1997. Question and answer session.
Frost, K. R., Bellman, P., Cohen, C. J., Currier, J., Dobkin, J., & Saag, M. (1998). Controversies in AIDS treatment. Proceedings from CME conference sponsored by Cornell University Medical College and the American Foundation for AIDS Research (AmFAR). November 8, 1997. Question and answer session. AIDS patient care and STDs, 12(7), 557-566.

Phenotypic and genotypic testing in clinical practice
Holodniy, M. (1998). Phenotypic and genotypic testing in clinical practice. AIDS PATIENT CARE AND STDS, 12(7), 527-531.

Zidovudine treatment in patients with primary (Acute) human immunodeficiency virus type 1 infection: A randomized, double-blind, placebo-controlled trial
Niu, M. T., Bethel, J., Holodniy, M., Standiford, H. C., & Schnittman, S. M. (1998). Zidovudine treatment in patients with primary (Acute) human immunodeficiency virus type 1 infection: A randomized, double-blind, placebo-controlled trial. JOURNAL OF INFECTIOUS DISEASES, 178(1), 80-91.

HIV quantitation in spiked vaginocervical secretions: lack of non-specific inhibitory factors
Holodniy, M., Anderson, D., Wright, D., Sharma, O., Cohn, J., & Reichelderferd, P. (1998). HIV quantitation in spiked vaginocervical secretions: lack of non-specific inhibitory factors. JOURNAL OF VIROLOGICAL METHODS, 72(2), 185-195.

Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays
Gingeras, T. R., Ghandour, G., Wang, E. G., Berno, A., Small, P. M., & Drenkow, J. (1998). Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. GENOME RESEARCH, 8(5), 435-448.

Human immunodeficiency virus type 1 populations in blood and semen
Delwart, E. L., Mullins, J. I., Gupta, P., Learn, G. H., Holodniy, M., & Singh, M. K. (1998). Human immunodeficiency virus type 1 populations in blood and semen. JOURNAL OF VIROLOGY, 72(1), 617-623.

The impact of active herpes simplex virus infection on human immunodeficiency virus load
Mole, L., RIPICH, S., Margolis, D., & Holodniy, M. (1997). The impact of active herpes simplex virus infection on human immunodeficiency virus load. JOURNAL OF INFECTIOUS DISEASES, 176(3), 766-770.

HIV-1 protease inhibitors - A review for clinicians
Deeks, S. G., Smith, M., Holodniy, M., & Kahn, J. O. (1997). HIV-1 protease inhibitors - A review for clinicians. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 277(2), 145-153.

Prescribing practice and cost of antibacterial prophylaxis for surgery at a US Veterans Affairs Hospital
Ryono, R. A., Jones, K. S., Coleman, R. W., & Holodniy, M. (1996). Prescribing practice and cost of antibacterial prophylaxis for surgery at a US Veterans Affairs Hospital. PHARMACOECONOMICS, 10(6), 630-643.

Evaluation of Chiron HIV-1/HIV-2 recombinant immunoblot assay
Kline, R. L., McNairn, D., Holodniy, M., Mole, L., Margolis, D., & Quinn, T. C. (1996). Evaluation of Chiron HIV-1/HIV-2 recombinant immunoblot assay. JOURNAL OF CLINICAL MICROBIOLOGY, 34(11), 2650-2653.

Human immunodeficiency virus reverse transcriptase codon 215 mutations diminish virologic response to didanosine-zidovudine therapy in subjects with non-syncytium-inducing phenotype
Holodniy, M., KATZENSTEIN, D., Mole, L., Winters, M., & Merigan, T. (1996). Human immunodeficiency virus reverse transcriptase codon 215 mutations diminish virologic response to didanosine-zidovudine therapy in subjects with non-syncytium-inducing phenotype. JOURNAL OF INFECTIOUS DISEASES, 174(4), 854-857.

HIV viral load markers in clinical practice
Saag, M. S., Holodniy, M., Kuritzkes, D. R., OBRIEN, W. A., COOMBS, R., & Volberding, P. A. (1996). HIV viral load markers in clinical practice. NATURE MEDICINE, 2(6), 625-629.

A meta-analytic evaluation of the polymerase chain reaction for the diagnosis of HIV infection in infants
Owens, D. K., Holodniy, M., McDonald, T. W., Scott, J., & Sonnad, S. (1996). A meta-analytic evaluation of the polymerase chain reaction for the diagnosis of HIV infection in infants. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 275(17), 1342-1348.

Polymerase chain reaction for the diagnosis of HIV infection in adults - A meta-analysis with recommendations for clinical practice and study design
Owens, D. K., Holodniy, M., Garber, A. M., Scott, J., Sonnad, S., & Schwartz, J. S. (1996). Polymerase chain reaction for the diagnosis of HIV infection in adults - A meta-analysis with recommendations for clinical practice and study design. ANNALS OF INTERNAL MEDICINE, 124(9), 803-?.

Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes
Cohen, O. J., Pantaleo, G., Holodniy, M., Fox, C. H., Orenstein, J. M., & Fauci, A. S. (1996). Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes. JOURNAL OF INFECTIOUS DISEASES, 173(4), 849-856.

Quantitative relationship between platelet count and plasma virion HIV RNA
Holodniy, M., Margolis, D., Carroll, R., Todd, J., & Mole, L. (1996). Quantitative relationship between platelet count and plasma virion HIV RNA. AIDS, 10(2), 232-233.

SAFETY, PHARMACOKINETICS, AND ANTIVIRAL RESPONSE OF CD4-IMMUNOGLOBULIN-G BY INTRAVENOUS BOLUS IN AIDS AND AIDS-RELATED COMPLEX
Collier, A. C., COOMBS, R. W., KATZENSTEIN, D., Holodniy, M., Gibson, J., & Corey, L. (1995). SAFETY, PHARMACOKINETICS, AND ANTIVIRAL RESPONSE OF CD4-IMMUNOGLOBULIN-G BY INTRAVENOUS BOLUS IN AIDS AND AIDS-RELATED COMPLEX. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 10(2), 150-156.

NONISOTOPIC HYBRIDIZATION ASSAY FOR DETERMINATION OF RELATIVE AMOUNTS OF GENOTYPIC HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ZIDOVUDINE RESISTANCE
Eastman, P. S., Boyer, E., Mole, L., Kolberg, J., Urdea, M., & Holodniy, M. (1995). NONISOTOPIC HYBRIDIZATION ASSAY FOR DETERMINATION OF RELATIVE AMOUNTS OF GENOTYPIC HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ZIDOVUDINE RESISTANCE. JOURNAL OF CLINICAL MICROBIOLOGY, 33(10), 2777-2780.

DECREASED HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PLASMA VIREMIA DURING ANTIRETROVIRAL THERAPY REFLECTS DOWN-REGULATION OF VIRAL REPLICATION IN LYMPHOID-TISSUE
Cohen, O. J., Pantaleo, G., Holodniy, M., SCHNITMAN, S., Niu, M., & Fauci, A. S. (1995). DECREASED HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 PLASMA VIREMIA DURING ANTIRETROVIRAL THERAPY REFLECTS DOWN-REGULATION OF VIRAL REPLICATION IN LYMPHOID-TISSUE. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 92(13), 6017-6021.

DETERMINATION OF HUMAN-IMMUNODEFICIENCY-VIRUS RNA IN PLASMA AND CELLULAR VIRAL-DNA GENOTYPIC ZIDOVUDINE RESISTANCE AND VIRAL LOAD DURING ZIDOVUDINE-DIDANOSINE COMBINATION THERAPY
Holodniy, M., Mole, L., Margolis, D., Moss, J., Dong, H. L., & Eastman, S. (1995). DETERMINATION OF HUMAN-IMMUNODEFICIENCY-VIRUS RNA IN PLASMA AND CELLULAR VIRAL-DNA GENOTYPIC ZIDOVUDINE RESISTANCE AND VIRAL LOAD DURING ZIDOVUDINE-DIDANOSINE COMBINATION THERAPY. JOURNAL OF VIROLOGY, 69(6), 3510-3516.

COMPARATIVE STABILITIES OF QUANTITATIVE HUMAN-IMMUNODEFICIENCY-VIRUS RNA IN PLASMA FROM SAMPLES COLLECTED IN VACUTAINER CPT, VACUTAINER PPT, AND STANDARD VACUTAINER TUBES
Holodniy, M., Mole, L., YENLIEBERMAN, B., Margolis, D., Starkey, C., & Jackson, J. B. (1995). COMPARATIVE STABILITIES OF QUANTITATIVE HUMAN-IMMUNODEFICIENCY-VIRUS RNA IN PLASMA FROM SAMPLES COLLECTED IN VACUTAINER CPT, VACUTAINER PPT, AND STANDARD VACUTAINER TUBES. JOURNAL OF CLINICAL MICROBIOLOGY, 33(6), 1562-1566.

PERFORMANCE-CHARACTERISTICS FOR THE QUANTITATION OF PLASMA HIV-1 RNA USING BRANCHED DNA SIGNAL AMPLIFICATION TECHNOLOGY
Todd, J., PACHL, C., White, R., Yeghiazarian, T., Johnson, P., & Urdea, M. (1995). PERFORMANCE-CHARACTERISTICS FOR THE QUANTITATION OF PLASMA HIV-1 RNA USING BRANCHED DNA SIGNAL AMPLIFICATION TECHNOLOGY. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 10, S35-S44.

HIV viral load quantification, HIV resistance, and antiretroviral therapy.
Katzenstein, D. A., & Holodniy, M. (1995). HIV viral load quantification, HIV resistance, and antiretroviral therapy. AIDS clinical review, 277-303.

DEFICIENCY IN ANTIBODY-RESPONSE TO HUMAN CYTOMEGALOVIRUS GLYCOPROTEIN GH IN HUMAN IMMUNODEFICIENCY VIRUS-TREATED PATIENTS AT RISK FOR CYTOMEGALOVIRUS RETINITIS
Rasmussen, L., Morris, S., Wolitz, R., Dowling, A., Fessell, J., & Merigan, T. C. (1994). DEFICIENCY IN ANTIBODY-RESPONSE TO HUMAN CYTOMEGALOVIRUS GLYCOPROTEIN GH IN HUMAN IMMUNODEFICIENCY VIRUS-TREATED PATIENTS AT RISK FOR CYTOMEGALOVIRUS RETINITIS. JOURNAL OF INFECTIOUS DISEASES, 170(3), 673-677.

STABILITIES OF QUANTITATIVE PLASMA CULTURE FOR HUMAN-IMMUNODEFICIENCY-VIRUS, RNA, AND P24 ANTIGEN FROM SAMPLES COLLECTED IN VACUTAINER CPT AND STANDARD VACUTAINER TUBES
Mole, L., Margolis, D., Carroll, R., Todd, J., & Holodniy, M. (1994). STABILITIES OF QUANTITATIVE PLASMA CULTURE FOR HUMAN-IMMUNODEFICIENCY-VIRUS, RNA, AND P24 ANTIGEN FROM SAMPLES COLLECTED IN VACUTAINER CPT AND STANDARD VACUTAINER TUBES. JOURNAL OF CLINICAL MICROBIOLOGY, 32(9), 2212-2215.

CLINICAL-APPLICATION OF REVERSE TRANSCRIPTION-POLYMERASE CHAIN-REACTION FOR HIV-INFECTION
Holodniy, M. (1994). CLINICAL-APPLICATION OF REVERSE TRANSCRIPTION-POLYMERASE CHAIN-REACTION FOR HIV-INFECTION. CLINICS IN LABORATORY MEDICINE, 14(2), 335-349.

ANTIBIOTIC-ASSOCIATED PSEUDOMEMBRANOUS ENTERITIS DUE TO CLOSTRIDIUM-DIFFICILE
TSUTAOKA, B., Hansen, J., Johnson, D., & Holodniy, M. (1994). ANTIBIOTIC-ASSOCIATED PSEUDOMEMBRANOUS ENTERITIS DUE TO CLOSTRIDIUM-DIFFICILE. CLINICAL INFECTIOUS DISEASES, 18(6), 982-984.

THE USE OF PENTOXIFYLLINE ALONE IN HIV-INFECTED PATIENTS
Mole, L., Margolis, D., Ghotbi, L., & Holodniy, M. (1994). THE USE OF PENTOXIFYLLINE ALONE IN HIV-INFECTED PATIENTS. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 7(5), 519-521.

DIURNAL AND SHORT-TERM STABILITY OF HIV VIRUS LOAD AS MEASURED BY GENE AMPLIFICATION
Holodniy, M., Mole, L., Winters, M., & Merigan, T. C. (1994). DIURNAL AND SHORT-TERM STABILITY OF HIV VIRUS LOAD AS MEASURED BY GENE AMPLIFICATION. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 7(4), 363-368.

DETECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 IN SEMEN - EFFECTS OF DISEASE STAGE AND NUCLEOSIDE THERAPY
Hamed, K. A., Winters, M. A., Holodniy, M., Katzenstein, D. A., & Merigan, T. C. (1993). DETECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 IN SEMEN - EFFECTS OF DISEASE STAGE AND NUCLEOSIDE THERAPY. JOURNAL OF INFECTIOUS DISEASES, 167(4), 798-802.

MEASUREMENT OF HIV VIRUS LOAD AND GENOTYPIC RESISTANCE BY GENE AMPLIFICATION IN ASYMPTOMATIC SUBJECTS TREATED WITH COMBINATION THERAPY
Holodniy, M., KATZENSTEIN, D., Winters, M., Montoya, J., Shafer, R., & Merigan, T. C. (1993). MEASUREMENT OF HIV VIRUS LOAD AND GENOTYPIC RESISTANCE BY GENE AMPLIFICATION IN ASYMPTOMATIC SUBJECTS TREATED WITH COMBINATION THERAPY. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 6(4), 366-369.

Peripheral blood mononuclear cell human immunodeficiency virus type 1 proviral DNA quantification by polymerase chain reaction: relationship to immunodeficiency and drug effect
Montoya, Jg., Wood R, Katzenstein D, Holodny M, & Merigan TC. (1993). Peripheral blood mononuclear cell human immunodeficiency virus type 1 proviral DNA quantification by polymerase chain reaction: relationship to immunodeficiency and drug effect. Journal of Clinical Microbiology, 31(10).

Quantitative RNA and DNA gene amplification can rapidly monitor HIV infection and antiviral activity in cell cultures.
Winters, M. A., Holodniy, M., Katzenstein, D. A., & Merigan, T. C. (1992). Quantitative RNA and DNA gene amplification can rapidly monitor HIV infection and antiviral activity in cell cultures. PCR methods and applications, 1(4), 257-262.

THE SULFONE SYNDROME IN A PATIENT RECEIVING DAPSONE PROPHYLAXIS FOR PNEUMOCYSTIS-CARINII PNEUMONIA
MOHLEBOETANI, J., AKULA, S. K., Holodniy, M., KATZENSTEIN, D., & Garcia, G. (1992). THE SULFONE SYNDROME IN A PATIENT RECEIVING DAPSONE PROPHYLAXIS FOR PNEUMOCYSTIS-CARINII PNEUMONIA. WESTERN JOURNAL OF MEDICINE, 156(3), 303-306.

CORRELATION OF MORPHOLOGICAL DIAGNOSIS OF PNEUMOCYSTIS-CARINII WITH THE PRESENCE OF PNEUMOCYSTIS DNA AMPLIFIED BY THE POLYMERASE CHAIN-REACTION
Blumenfeld, W., McCook, O., Holodniy, M., & Katzenstein, D. A. (1992). CORRELATION OF MORPHOLOGICAL DIAGNOSIS OF PNEUMOCYSTIS-CARINII WITH THE PRESENCE OF PNEUMOCYSTIS DNA AMPLIFIED BY THE POLYMERASE CHAIN-REACTION. MODERN PATHOLOGY, 5(2), 103-106.

PLASMA VIREMIA IN HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - RELATIONSHIP TO STAGE OF DISEASE AND ANTIVIRAL TREATMENT
Katzenstein, D. A., Holodniy, M., Israelski, D. M., Sengupta, S., Mole, L. A., & Merigan, T. C. (1992). PLASMA VIREMIA IN HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - RELATIONSHIP TO STAGE OF DISEASE AND ANTIVIRAL TREATMENT. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 5(2), 107-112.

DETECTION AND QUANTIFICATION OF GENE AMPLIFICATION PRODUCTS BY A NONISOTOPIC AUTOMATED-SYSTEM
Holodniy, M., Winters, M. A., & Merigan, T. C. (1992). DETECTION AND QUANTIFICATION OF GENE AMPLIFICATION PRODUCTS BY A NONISOTOPIC AUTOMATED-SYSTEM. BIOTECHNIQUES, 12(1), 36-?.

DECREASE IN HIV PROVIRUS IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS DURING ZIDOVUDINE AND HUMAN RIL-2 ADMINISTRATION
Clark, A. Gb., Holodniy, M., Schwartz, D. H., Katzenstein, D. A., & Merigan, T. C. (1992). DECREASE IN HIV PROVIRUS IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS DURING ZIDOVUDINE AND HUMAN RIL-2 ADMINISTRATION. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 5(1), 52-59.

Quantitative virological measures of antiretroviral therapy.
Katzenstein, D. A., & Holodniy, M. (1992). Quantitative virological measures of antiretroviral therapy. AIDS clinical review, 41-67.

REDUCTION IN PLASMA HUMAN-IMMUNODEFICIENCY-VIRUS RIBONUCLEIC-ACID AFTER DIDEOXYNUCLEOSIDE THERAPY AS DETERMINED BY THE POLYMERASE CHAIN-REACTION
Holodniy, M., Katzenstein, D. A., Israelski, D. M., & Merigan, T. C. (1991). REDUCTION IN PLASMA HUMAN-IMMUNODEFICIENCY-VIRUS RIBONUCLEIC-ACID AFTER DIDEOXYNUCLEOSIDE THERAPY AS DETERMINED BY THE POLYMERASE CHAIN-REACTION. JOURNAL OF CLINICAL INVESTIGATION, 88(5), 1755-1759.

DETECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS DNA AND RNA IN SEMEN BY THE POLYMERASE CHAIN-REACTION
Mermin, J. H., Holodniy, M., Katzenstein, D. A., & Merigan, T. C. (1991). DETECTION OF HUMAN-IMMUNODEFICIENCY-VIRUS DNA AND RNA IN SEMEN BY THE POLYMERASE CHAIN-REACTION. JOURNAL OF INFECTIOUS DISEASES, 164(4), 769-772.

INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS GENE AMPLIFICATION BY HEPARIN
Holodniy, M., Kim, S., KATZENSTEIN, D., Konrad, M., Groves, E., & Merigan, T. C. (1991). INHIBITION OF HUMAN-IMMUNODEFICIENCY-VIRUS GENE AMPLIFICATION BY HEPARIN. JOURNAL OF CLINICAL MICROBIOLOGY, 29(4), 676-679.

DETECTION AND QUANTIFICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS RNA IN PATIENT SERUM BY USE OF THE POLYMERASE CHAIN-REACTION
Holodniy, M., Katzenstein, D. A., Sengupta, S., Wang, A. M., CASIPIT, C., & Merigan, T. C. (1991). DETECTION AND QUANTIFICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS RNA IN PATIENT SERUM BY USE OF THE POLYMERASE CHAIN-REACTION. JOURNAL OF INFECTIOUS DISEASES, 163(4), 862-866.

CORRELATION BETWEEN HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) LOAD, STAGE OF DISEASE AND DIDEOXY DRUG ADMINISTRATION USING QUANTITATIVE RNA AND DNA-POLYMERASE CHAIN-REACTION (PCR) AND VIREMIA MEASUREMENTS
Merigan, T. C., Clark, G., KATZENSTEIN, D., & Holodniy, M. (1991). CORRELATION BETWEEN HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) LOAD, STAGE OF DISEASE AND DIDEOXY DRUG ADMINISTRATION USING QUANTITATIVE RNA AND DNA-POLYMERASE CHAIN-REACTION (PCR) AND VIREMIA MEASUREMENTS. VIRAL QUANTITATION IN HIV INFECTION, 147-152.

CEREBRAL SPARGANOSIS - CASE-REPORT AND REVIEW
Holodniy, M., ALMENOFF, J., Loutit, J., & Steinberg, G. K. (1991). CEREBRAL SPARGANOSIS - CASE-REPORT AND REVIEW. REVIEWS OF INFECTIOUS DISEASES, 13(1), 155-159.

Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial.
Schooley, R. T., Merigan, T. C., Gaut, P., Hirsch, M. S., Holodniy, M., & Gubish, E. (1990). Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase I-II escalating dosage trial. Annals of internal medicine, 112(4), 247-253.

FULMINANT KAPOSIS-SARCOMA COMPLICATING LONG-TERM CORTICOSTEROID-THERAPY
KOOP, H. O., Holodniy, M., & List, A. F. (1987). FULMINANT KAPOSIS-SARCOMA COMPLICATING LONG-TERM CORTICOSTEROID-THERAPY. AMERICAN JOURNAL OF MEDICINE, 83(4), 787-789.