Robert Harrington

Arthur L. Bloomfield Professor of Medicine

Professional Education

Residency: Univ Of Ma Med Sch - Worcester (1990) MA

Board Certification: Cardiovascular Disease, American Board of Internal Medicine (1993)

Fellowship: Duke University Medical Center (1993) NC

Board Certification: Internal Medicine, American Board of Internal Medicine (1989)

Internship: Univ Of Ma Med Sch - Worcester (1987) MA

Medical Education: Tufts University School of Medicine (1986) MA

A novel approach to systematically implement the universal definition of myocardial infarction: insights from the CHAMPION PLATFORM trial
Leonardi, S., Truffa, A. A., Neely, M. L., Tricoci, P., White, H. D., & Mahaffey, K. W. (2013). A novel approach to systematically implement the universal definition of myocardial infarction: insights from the CHAMPION PLATFORM trial. HEART, 99(17), 1282-1287.

Cardiac Troponin After Percutaneous Coronary Intervention and 1-Year Mortality in Non-ST-Segment Elevation Acute Coronary Syndrome Using Systematic Evaluation of Biomarker Trends
Tricoci, P., Leonardi, S., White, J., White, H. D., Armstrong, P. W., & Newby, L. K. (2013). Cardiac Troponin After Percutaneous Coronary Intervention and 1-Year Mortality in Non-ST-Segment Elevation Acute Coronary Syndrome Using Systematic Evaluation of Biomarker Trends. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 62(3), 242-251.

Effect of vorapaxar on myocardial infarction in the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome (TRA.CER) trial
Leonardi, S., Tricoci, P., White, H. D., Armstrong, P. W., Huang, Z., & Mahaffey, K. W. (2013). Effect of vorapaxar on myocardial infarction in the thrombin receptor antagonist for clinical event reduction in acute coronary syndrome (TRA.CER) trial. EUROPEAN HEART JOURNAL, 34(23), 1723-1731.

Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events
Bhatt, D. L., Stone, G. W., Mahaffey, K. W., Gibson, C. M., Steg, P. G., & Harrington, R. A. (2013). Effect of Platelet Inhibition with Cangrelor during PCI on Ischemic Events. NEW ENGLAND JOURNAL OF MEDICINE, 368(14), 1303-1313.

Left Bundle Branch Block in Non-ST-Segment Elevation Acute Coronary Syndromes Incidence, Angiographic Characteristics, and Clinical Outcomes
Rose, J. J., Newby, L. K., Broderick, S., Chiswell, K., Van de Werf, F., & Lopes, R. D. (2013). Left Bundle Branch Block in Non-ST-Segment Elevation Acute Coronary Syndromes Incidence, Angiographic Characteristics, and Clinical Outcomes. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 61(13), 1461-1463.

Radial versus femoral access, bleeding and ischemic events in patients with non-ST-segment elevation acute coronary syndrome managed with an invasive strategy
Klutstein, M. W., Westerhout, C. M., Armstrong, P. W., Giugliano, R. P., Lewis, B. S., & Rao, S. V. (2013). Radial versus femoral access, bleeding and ischemic events in patients with non-ST-segment elevation acute coronary syndrome managed with an invasive strategy. AMERICAN HEART JOURNAL, 165(4), 583-?.

Venous thromboembolism prophylaxis: do trial results enable clinicians and patients to evaluate whether the benefits justify the risk? Proceedings of an Ad Hoc Working Group Meeting
Berger, J., Eikelboom, J. W., Quinlan, D. J., Guyatt, G., Buller, H. R., & Hirsh, J. (2013). Venous thromboembolism prophylaxis: do trial results enable clinicians and patients to evaluate whether the benefits justify the risk? Proceedings of an Ad Hoc Working Group Meeting. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 11(4), 778-782.

ACP Journal Club. PCI using drug-eluting stents had higher mortality than CABG in diabetes and multivessel CAD.
Harrington, R. A. (2013). ACP Journal Club. PCI using drug-eluting stents had higher mortality than CABG in diabetes and multivessel CAD. Annals of internal medicine, 158(6), JC8-?.

2013 ACCF/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes and coronary artery disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Acute Coronary Syndromes and Coronary Artery Disease Clinical Data Standards).
Cannon, C. P., Brindis, R. G., Chaitman, B. R., Cohen, D. J., Cross, J. T., & Weintraub, W. S. (2013). 2013 ACCF/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes and coronary artery disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Acute Coronary Syndromes and Coronary Artery Disease Clinical Data Standards). Circulation, 127(9), 1052-1089.

2013 ACCF/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes and coronary artery disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on clinical data standards (writing committee to develop acute coronary syndromes and coronary artery disease clinical data standards).
Cannon, C. P., Brindis, R. G., Chaitman, B. R., Cohen, D. J., Cross, J. T., & Weintraub, W. S. (2013). 2013 ACCF/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes and coronary artery disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on clinical data standards (writing committee to develop acute coronary syndromes and coronary artery disease clinical data standards). Journal of the American College of Cardiology, 61(9), 992-1025.

A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia.
Onken, J. E., Bregman, D. B., Harrington, R. A., Morris, D., Acs, P., & Goodnough, L. T. (2013). A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia. Transfusion.

Quantitative ST-depression in Acute Coronary Syndromes: the PLATO Electrocardiographic Substudy.
Armstrong, P. W., Westerhout, C. M., Fu, Y., Harrington, R. A., Storey, R. F., & Wallentin, L. (2013). Quantitative ST-depression in Acute Coronary Syndromes: the PLATO Electrocardiographic Substudy. The American journal of medicine, 126(8), 723-729.e1.

Response to letter regarding article, "ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials".
James, S. K., Storey, R. F., Pieper, K. S., Cannon, C. P., & Becker, R. C. (2013). Response to letter regarding article, "ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials". Stroke; a journal of cerebral circulation, 44(8), e95-6.

2013 ACCF/AHA Key Data Elements and Definitions for Measuring the Clinical Management and Outcomes of Patients With Acute Coronary Syndromes and Coronary Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Acute Coronary Syndromes and Coronary Artery Disease Clinical Data Standards).
Cannon, C. P., Brindis, R. G., Chaitman, B. R., Cohen, D. J., Cross, J. T., & Weintraub, W. S. (2013). 2013 ACCF/AHA Key Data Elements and Definitions for Measuring the Clinical Management and Outcomes of Patients With Acute Coronary Syndromes and Coronary Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Acute Coronary Syndromes and Coronary Artery Disease Clinical Data Standards). Critical pathways in cardiology, 12(2), 65-105.

Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting.
Williams, J. B., Lopes, R. D., Hafley, G. E., Bruce Ferguson, T., Mack, M. J., & Alexander, J. H. (2013). Relationship between postoperative clopidogrel use and subsequent angiographic and clinical outcomes following coronary artery bypass grafting. Journal of thrombosis and thrombolysis.

Angiographic Outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes).
Kunadian, V., James, S. K., Wojdyla, D. M., Zorkun, C., Wu, J., & Gibson, C. M. (2013). Angiographic Outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes). JACC. Cardiovascular interventions, 6(7), 671-83.

Platelet inhibition with cangrelor during PCI.
Bhatt, D. L., & Harrington, R. A. (2013). Platelet inhibition with cangrelor during PCI. The New England journal of medicine, 369(4), 393-4.

Response to letter regarding article, “sustained ventricular tachycardia and ventricular fibrillation complicating non–ST-segment elevation acute coronary syndromes”.
Piccini, J. P., White, J. A., Mehta, R. H., Lokhnygina, Y., Al-Khatib, S. M., & Giugliano, R. P. (2013). Response to letter regarding article, “sustained ventricular tachycardia and ventricular fibrillation complicating non–ST-segment elevation acute coronary syndromes”. Circulation, 127(20), e634.

ACP Journal Club. Intraaortic balloon counterpulsation did not reduce mortality in acute MI with cardiogenic shock.
Harrington, R. A. (2012). ACP Journal Club. Intraaortic balloon counterpulsation did not reduce mortality in acute MI with cardiogenic shock. Annals of internal medicine, 157(12), JC6-11.

Conversion of Cardiovascular Conference Abstracts to Publications
Fosbol, E. L., Fosbol, P. L., Harrington, R. A., Eapen, Z. J., & Peterson, E. D. (2012). Conversion of Cardiovascular Conference Abstracts to Publications. CIRCULATION, 126(24), 2819-?.

Are Central Institutional Review Boards the Solution? The National Heart, Lung, and Blood Institute Working Group's Report on Optimizing the IRB Process
Mascette, A. M., Bernard, G. R., DiMichele, D., Goldner, J. A., Harrington, R., & Wagner, T. H. (2012). Are Central Institutional Review Boards the Solution? The National Heart, Lung, and Blood Institute Working Group's Report on Optimizing the IRB Process. ACADEMIC MEDICINE, 87(12), 1710-1714.

Transforming Clinical Trials in Cardiovascular Disease Mission Critical for Health and Economic Well-being
Antman, E. M., & Harrington, R. A. (2012). Transforming Clinical Trials in Cardiovascular Disease Mission Critical for Health and Economic Well-being. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 308(17), 1743-1744.

Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery: An analysis from ACT34-CMI
Povsic, T. J., Losordo, D. W., Story, K., Junge, C. E., Schatz, R. A., & Henry, T. D. (2012). Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery: An analysis from ACT34-CMI. AMERICAN HEART JOURNAL, 164(5), 689-U86.

Road mapping ATLAS ACS 2: are we there yet?
Armstrong, P. W., & Harrington, R. A. (2012). Road mapping ATLAS ACS 2: are we there yet?. EUROPEAN HEART JOURNAL, 33(20), 2510-2512.

Association Between Angiographic Complications and Clinical Outcomes Among Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention An EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) Angiographic Substudy
Pride, Y. B., Mohanavelu, S., Zorkun, C., Kunadian, V., Giugliano, R. P., & Gibson, C. M. (2012). Association Between Angiographic Complications and Clinical Outcomes Among Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention An EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) Angiographic Substudy. JACC-CARDIOVASCULAR INTERVENTIONS, 5(9), 927-935.

2012 American College of Cardiology Foundation/Society for Cardiovascular Angiography and Interventions expert consensus document on cardiac catheterization laboratory standards update: American College of Cardiology Foundation Task Force on expert consensus documents Society of Thoracic Surgeons Society for Vascular Medicine.
Bashore, T. M., Balter, S., Barac, A., Byrne, J. G., Cavendish, J. J., & Gardner. (2012). 2012 American College of Cardiology Foundation/Society for Cardiovascular Angiography and Interventions expert consensus document on cardiac catheterization laboratory standards update: American College of Cardiology Foundation Task Force on expert consensus documents Society of Thoracic Surgeons Society for Vascular Medicine. Catheterization and cardiovascular interventions , 80(3), E37-49.

Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results
Lopes, R. D., Williams, J. B., Mehta, R. H., Reyes, E. M., Hafley, G. E., & Alexander, J. H. (2012). Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results. AMERICAN HEART JOURNAL, 164(3), 379-U284.

Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial
Cornel, J. H., Becker, R. C., Goodman, S. G., Husted, S., Katus, H., & James, S. (2012). Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial. AMERICAN HEART JOURNAL, 164(3), 334-U239.

2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement: developed in collabration with the American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance.
Holmes, D. R., Mack, M. J., Kaul, S., Agnihotri, A., Alexander, K. P., & Weitz, H. H. (2012). 2012 ACCF/AATS/SCAI/STS expert consensus document on transcatheter aortic valve replacement: developed in collabration with the American Heart Association, American Society of Echocardiography, European Association for Cardio-Thoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance. journal of thoracic and cardiovascular surgery, 144(3), e29-84.

Lecture Halls without Lectures
Eapen, Z. J., Vavalle, J. P., & Harrington, R. A. (2012). Lecture Halls without Lectures. NEW ENGLAND JOURNAL OF MEDICINE, 367(7), 678-678.

Effect of Adenosine-Regulating Agent Acadesine on Morbidity and Mortality Associated With Coronary Artery Bypass Grafting The RED-CABG Randomized Controlled Trial
Newman, M. F., Ferguson, T. B., White, J. A., Ambrosio, G., Koglin, J., & Harrington, R. A. (2012). Effect of Adenosine-Regulating Agent Acadesine on Morbidity and Mortality Associated With Coronary Artery Bypass Grafting The RED-CABG Randomized Controlled Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 308(2), 157-164.

Usefulness of Medical Conferences
Antman, E. M., Harrington, R., & Tomaselli, G. (2012). Usefulness of Medical Conferences. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 308(1), 31-32.

Sustained Ventricular Tachycardia and Ventricular Fibrillation Complicating Non-ST-Segment-Elevation Acute Coronary Syndromes
Piccini, J. P., White, J. A., Mehta, R. H., Lokhnygina, Y., Al-Khatib, S. M., & Newby, L. K. (2012). Sustained Ventricular Tachycardia and Ventricular Fibrillation Complicating Non-ST-Segment-Elevation Acute Coronary Syndromes. CIRCULATION, 126(1), 41-49.

Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil
Lopes, R. D., Becker, R. C., Newby, L. K., Peterson, E. D., Hylek, E. M., & Garcia, D. A. (2012). Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 34(1), 143-163.

Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials
Angiolillo, D. J., Schneider, D. J., Bhatt, D. L., French, W. J., Price, M. J., & Becker, R. C. (2012). Pharmacodynamic effects of cangrelor and clopidogrel: the platelet function substudy from the cangrelor versus standard therapy to achieve optimal management of platelet inhibition (CHAMPION) trials. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 34(1), 44-55.

2012 ACCF/AATS/SCAI/STS Expert Consensus Document on Transcatheter Aortic Valve Replacement Developed in collaboration with the American Heart Association, American Society of Echocardiography, European Association for CardioThoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance
Holmes, D. R., Mack, M. J., Kaul, S., Agnihotri, A., Alexander, K. P., & Weitz, H. H. (2012). 2012 ACCF/AATS/SCAI/STS Expert Consensus Document on Transcatheter Aortic Valve Replacement Developed in collaboration with the American Heart Association, American Society of Echocardiography, European Association for CardioThoracic Surgery, Heart Failure Society of America, Mended Hearts, Society of Cardiovascular Anesthesiologists, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 79(7), 1023-1082.

Pharmacokinetic and Pharmacodynamic Effects of Elinogrel Results of the Platelet Function Substudy From the Intravenous and Oral Administration of Elinogrel to Evaluate Tolerability and Efficacy in Nonurgent Percutaneous Coronary Intervention Patients (INNOVATE-PCI) Trial
Angiolillo, D. J., Welsh, R. C., Trenk, D., Neumann, F.-J., Conley, P. B., & Rao, S. V. (2012). Pharmacokinetic and Pharmacodynamic Effects of Elinogrel Results of the Platelet Function Substudy From the Intravenous and Oral Administration of Elinogrel to Evaluate Tolerability and Efficacy in Nonurgent Percutaneous Coronary Intervention Patients (INNOVATE-PCI) Trial. CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 5(3), 347-356.

A Randomized, Double-Blind, Active-Controlled Phase 2 Trial to Evaluate a Novel Selective and Reversible Intravenous and Oral P2Y(12) Inhibitor Elinogrel Versus Clopidogrel in Patients Undergoing Nonurgent Percutaneous Coronary Intervention The INNOVATE-PCI Trial
Welsh, R. C., Rao, S. V., Zeymer, U., Thompson, V. P., Huber, K., & Harrington, R. A. (2012). A Randomized, Double-Blind, Active-Controlled Phase 2 Trial to Evaluate a Novel Selective and Reversible Intravenous and Oral P2Y(12) Inhibitor Elinogrel Versus Clopidogrel in Patients Undergoing Nonurgent Percutaneous Coronary Intervention The INNOVATE-PCI Trial. CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 5(3), 336-346.

Rationale and design of the Cangrelor versus standard therapy to acHieve optimal Management of Platelet InhibitiON PHOENIX trial
Leonardi, S., Mahaffey, K. W., White, H. D., Gibson, C. M., Stone, G. W., & Bhatt, D. L. (2012). Rationale and design of the Cangrelor versus standard therapy to acHieve optimal Management of Platelet InhibitiON PHOENIX trial. AMERICAN HEART JOURNAL, 163(5), 768-?.

Regional Patterns of Use of a Medical Management Strategy for Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Insights From the EARLY ACS Trial
Roe, M. T., White, J. A., Kaul, P., Tricoci, P., Lokhnygina, Y., & Newby, L. K. (2012). Regional Patterns of Use of a Medical Management Strategy for Patients With Non-ST-Segment Elevation Acute Coronary Syndromes Insights From the EARLY ACS Trial. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 5(2), 205-213.

Association of Proton Pump Inhibitor Use on Cardiovascular Outcomes With Clopidogrel and Ticagrelor Insights From the Platelet Inhibition and Patient Outcomes Trial
Goodman, S. G., Clare, R., Pieper, K. S., Nicolau, J. C., Storey, R. F., & Wallentin, L. (2012). Association of Proton Pump Inhibitor Use on Cardiovascular Outcomes With Clopidogrel and Ticagrelor Insights From the Platelet Inhibition and Patient Outcomes Trial. CIRCULATION, 125(8), 978-986.

Relationship Between Vein Graft Failure and Subsequent Clinical Outcomes After Coronary Artery Bypass Surgery
Lopes, R. D., Mehta, R. H., Hafley, G. E., Williams, J. B., Mack, M. J., & Alexander, J. H. (2012). Relationship Between Vein Graft Failure and Subsequent Clinical Outcomes After Coronary Artery Bypass Surgery. CIRCULATION, 125(6), 749-756.

Reduced immediate ischemic events with cangrelor in PCI: A pooled analysis of the CHAMPION trials using the universal definition of myocardial infarction
White, H. D., Chew, D. P., Dauerman, H. L., Mahaffey, K. W., Gibson, C. M., & Bhatt, D. L. (2012). Reduced immediate ischemic events with cangrelor in PCI: A pooled analysis of the CHAMPION trials using the universal definition of myocardial infarction. AMERICAN HEART JOURNAL, 163(2), 182-U275.

ST-Elevation Acute Coronary Syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) Trial Insights From the ECG Substudy
Armstrong, P. W., Siha, H., Fu, Y., Westerhout, C. M., Steg, P. G., & Wallentin, L. (2012). ST-Elevation Acute Coronary Syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) Trial Insights From the ECG Substudy. CIRCULATION, 125(3), 514-U131.

Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes
Tricoci, P., Huang, Z., Held, C., Moliterno, D. J., Armstrong, P. W., & Mahaffey, K. W. (2012). Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes. NEW ENGLAND JOURNAL OF MEDICINE, 366(1), 20-33.

Venous thromboembolism prophylaxis: do trial results enable clinicians and patients to evaluate whether the benefits justify the risk? proceedings of an ad hoc working group meeting.
Berger, J., Eikelboom, J. W., Quinlan, D. J., Guyatt, G., Büller, H. R., & Hirsh, J. (2012). Venous thromboembolism prophylaxis: do trial results enable clinicians and patients to evaluate whether the benefits justify the risk? proceedings of an ad hoc working group meeting. Journal of thrombosis and haemostasis : JTH.

Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: Insights from the EARLY ACS trial.
Lopes, R. D., White, J. A., Tricoci, P., White, H. D., Armstrong, P. W., & Newby, L. K. (2012). Age, treatment, and outcomes in high-risk non-ST-segment elevation acute coronary syndrome patients: Insights from the EARLY ACS trial. International journal of cardiology.

Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15years.
Chan, M. Y., Sun, J. L., Newby, L. K., Lokhnygina, Y., White, H. D., & Harrington, R. A. (2012). Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15years. International journal of cardiology.

Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial
Becker, R. C., Bassand, J. P., Budaj, A., Wojdyla, D. M., James, S. K., & Wallentin, L. (2011). Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial. EUROPEAN HEART JOURNAL, 32(23), 2933-2944.

Pulmonary Function in Patients With Acute Coronary Syndrome Treated With Ticagrelor or Clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] Pulmonary Function Substudy)
Storey, R. F., Becker, R. C., Harrington, R. A., Husted, S., James, S. K., & Wallentin, L. (2011). Pulmonary Function in Patients With Acute Coronary Syndrome Treated With Ticagrelor or Clopidogrel (from the Platelet Inhibition and Patient Outcomes [PLATO] Pulmonary Function Substudy). AMERICAN JOURNAL OF CARDIOLOGY, 108(11), 1542-1546.

Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes
Storey, R. F., Becker, R. C., Harrington, R. A., Husted, S., James, S. K., & Wallentin, L. (2011). Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. EUROPEAN HEART JOURNAL, 32(23), 2945-2953.

Safety and efficacy of adjusted-dose eptifibatide in patients with acute coronary syndromes and reduced renal function
Melloni, C., James, S. K., White, J. A., Giugliano, R. P., Harrington, R. A., & Newby, L. K. (2011). Safety and efficacy of adjusted-dose eptifibatide in patients with acute coronary syndromes and reduced renal function. AMERICAN HEART JOURNAL, 162(5).

Apixaban with Antiplatelet Therapy after Acute Coronary Syndrome
Alexander, J. H., Lopes, R. D., James, S., Kilaru, R., He, Y., & Wallentin, L. (2011). Apixaban with Antiplatelet Therapy after Acute Coronary Syndrome. NEW ENGLAND JOURNAL OF MEDICINE, 365(8), 699-708.

Biomedical Innovation: A Risky Business at Risk
Stack, R. S., & Harrington, R. A. (2011). Biomedical Innovation: A Risky Business at Risk. SCIENCE TRANSLATIONAL MEDICINE, 3(96).

American Industry and the U.S. Cardiovascular Clinical Research Enterprise An Appropriate Analogy?
Califf, R. M., & Harrington, R. A. (2011). American Industry and the U.S. Cardiovascular Clinical Research Enterprise An Appropriate Analogy?. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 58(7), 677-680.

Intramyocardial, Autologous CD34+Cell Therapy for Refractory Angina
Losordo, D. W., Henry, T. D., Davidson, C., Lee, J. S., Costa, M. A., & Schatz, R. A. (2011). Intramyocardial, Autologous CD34+Cell Therapy for Refractory Angina. CIRCULATION RESEARCH, 109(4), 428-U235.

Ticagrelor Compared With Clopidogrel by Geographic Region in the Platelet Inhibition and Patient Outcomes (PLATO) Trial
Mahaffey, K. W., Wojdyla, D. M., Carroll, K., Becker, R. C., Storey, R. F., & Wallentin, L. (2011). Ticagrelor Compared With Clopidogrel by Geographic Region in the Platelet Inhibition and Patient Outcomes (PLATO) Trial. CIRCULATION, 124(5), 544-U78.

Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, Sao Paulo, Brazil
Lopes, R. D., Becker, R. C., Alexander, J. H., Armstrong, P. W., Califf, R. M., & Garcia, D. A. (2011). Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14-16, 2010, Sao Paulo, Brazil. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 32(2), 242-266.

Saphenous Vein Grafts With Multiple Versus Single Distal Targets in Patients Undergoing Coronary Artery Bypass Surgery One-Year Graft Failure and Five-Year Outcomes From the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial
Mehta, R. H., Ferguson, T. B., Lopes, R. D., Hafley, G. E., Mack, M. J., & Alexander, J. H. (2011). Saphenous Vein Grafts With Multiple Versus Single Distal Targets in Patients Undergoing Coronary Artery Bypass Surgery One-Year Graft Failure and Five-Year Outcomes From the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV Trial. CIRCULATION, 124(3), 280-288.

Dose Selection for a Direct and Selective Factor IXa Inhibitor and its Complementary Reversal Agent: Translating Pharmacokinetic and Pharmacodynamic Properties of the REG1 System to Clinical Trial Design
Povsic, T. J., Cohen, M. G., Chan, M. Y., Zelenkofske, S. L., WARGIN, W. A., & Becker, R. C. (2011). Dose Selection for a Direct and Selective Factor IXa Inhibitor and its Complementary Reversal Agent: Translating Pharmacokinetic and Pharmacodynamic Properties of the REG1 System to Clinical Trial Design. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 32(1), 21-31.

Upstream Use of Small-Molecule Glycoprotein IIb/IIIa Inhibitors in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes A Systematic Overview of Randomized Clinical Trials
Tricoci, P., Newby, L. K., Hasselblad, V., Kong, D. F., Giugliano, R. P., & Harrington, R. A. (2011). Upstream Use of Small-Molecule Glycoprotein IIb/IIIa Inhibitors in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes A Systematic Overview of Randomized Clinical Trials. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 4(4), 448-458.

Dueling Registries? An Alternative Perspective and the Case for Competitive Collaboration
Harrington, R. A. (2011). Dueling Registries? An Alternative Perspective and the Case for Competitive Collaboration. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 4(4), 486-487.

ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents Developed in Collaboration With the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension
Aronow, W. S., Fleg, J. L., Pepine, C. J., Artinian, N. T., Bakris, G., & Wesley, D. J. (2011). ACCF/AHA 2011 Expert Consensus Document on Hypertension in the Elderly A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents Developed in Collaboration With the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 5(4), 259-352.

Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial
James, S. K., Roe, M. T., Cannon, C. P., Cornel, J. H., Horrow, J., & Harrington, R. A. (2011). Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial. BRITISH MEDICAL JOURNAL, 342.

ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents.
Aronow, W. S., Fleg, J. L., Pepine, C. J., Artinian, N. T., Bakris, G., & Harrington, R. A. (2011). ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Circulation, 123(21), 2434-2506.

Intravenous Erythropoietin in Patients With ST-Segment Elevation Myocardial Infarction REVEAL: A Randomized Controlled Trial
Najjar, S. S., Rao, S. V., Melloni, C., Raman, S. V., Povsic, T. J., & Harrington, R. A. (2011). Intravenous Erythropoietin in Patients With ST-Segment Elevation Myocardial Infarction REVEAL: A Randomized Controlled Trial. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 305(18), 1863-1872.

The Incidence of Bradyarrhythmias and Clinical Bradyarrhythmic Events in Patients With Acute Coronary Syndromes Treated With Ticagrelor or Clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) Trial Results of the Continuous Electrocardiographic Assessment Substudy
Scirica, B. M., Cannon, C. P., Emanuelsson, H., Michelson, E. L., Harrington, R. A., & Wallentin, L. (2011). The Incidence of Bradyarrhythmias and Clinical Bradyarrhythmic Events in Patients With Acute Coronary Syndromes Treated With Ticagrelor or Clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) Trial Results of the Continuous Electrocardiographic Assessment Substudy. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 57(19), 1908-1916.

The PLATO trial reveals further opportunities to improve outcomes in patients with acute coronary syndrome. Editorial on Serebruany. "Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified" (Thromb Haemost 2011; 105.5).
Wallentin, L., Becker, R. C., James, S. K., & Harrington, R. A. (2011). The PLATO trial reveals further opportunities to improve outcomes in patients with acute coronary syndrome. Editorial on Serebruany. "Viewpoint: Paradoxical excess mortality in the PLATO trial should be independently verified" (Thromb Haemost 2011; 105.5). Thrombosis and haemostasis, 105(5), 760-762.

Upstream Clopidogrel Use and the Efficacy and Safety of Early Eptifibatide Treatment in Patients With Acute Coronary Syndrome An Analysis From the Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) Trial
Wang, T. Y., White, J. A., Tricoci, P., Giugliano, R. P., Zeymer, U., & Newby, L. K. (2011). Upstream Clopidogrel Use and the Efficacy and Safety of Early Eptifibatide Treatment in Patients With Acute Coronary Syndrome An Analysis From the Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) Trial. CIRCULATION, 123(7), 722-730.

Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery Results From the PLATO (Platelet Inhibition and Patient Outcomes) Trial
Held, C., Asenblad, N., Bassand, J. P., Becker, R. C., Cannon, C. P., & Wallentin, L. (2011). Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes Undergoing Coronary Artery Bypass Surgery Results From the PLATO (Platelet Inhibition and Patient Outcomes) Trial. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 57(6), 672-684.

Impact of Recovery of Renal Function on Long-Term Mortality After Coronary Artery Bypass Grafting
Mehta, R. H., Honeycutt, E., Patel, U. D., Lopes, R. D., Shaw, L. K., & Sketch, M. H. (2010). Impact of Recovery of Renal Function on Long-Term Mortality After Coronary Artery Bypass Grafting. AMERICAN JOURNAL OF CARDIOLOGY, 106(12), 1728-1734.

Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: A pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY
Chan, M. Y., Sun, J. L., Wang, T. Y., Lopes, R. D., Jolicoeur, M. E., & Peterson, E. D. (2010). Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: A pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY. AMERICAN HEART JOURNAL, 160(6), 1056-U95.

Randomized, Double-Blind, Placebo-Controlled Trial of Autologous CD34+Cell Therapy for Refractory Angina: 2-Year Safety Analysis
Losordo, D. W., Henry, T. D., Schatz, R. A., Lee, J. S., Costa, M., & Harrington, R. A. (2010). Randomized, Double-Blind, Placebo-Controlled Trial of Autologous CD34+Cell Therapy for Refractory Angina: 2-Year Safety Analysis. CIRCULATION, 122(21).

ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance.
Taylor, A. J., Cerqueira, M., Hodgson, J. Mb., Mark, D., Min, J., & Smith, S. C. (2010). ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance. Journal of the American College of Cardiology, 56(22), 1864-1894.

Ticagrelor Versus Clopidogrel in Patients With ST-Elevation Acute Coronary Syndromes Intended for Reperfusion With Primary Percutaneous Coronary Intervention A Platelet Inhibition and Patient Outcomes (PLATO) Trial Subgroup Analysis
Steg, P. G., James, S., Harrington, R. A., Ardissino, D., Becker, R. C., & Wallentin, L. (2010). Ticagrelor Versus Clopidogrel in Patients With ST-Elevation Acute Coronary Syndromes Intended for Reperfusion With Primary Percutaneous Coronary Intervention A Platelet Inhibition and Patient Outcomes (PLATO) Trial Subgroup Analysis. CIRCULATION, 122(21), 2131-2141.

Design and rationale of the Reduction of Infarct Expansion and Ventricular Remodeling with Erythropoietin after Large Myocardial Infarction (REVEAL) trial
Melloni, C., Rao, S. V., Povsic, T. J., Melton, L., Kim, R. J., & Harrington, R. A. (2010). Design and rationale of the Reduction of Infarct Expansion and Ventricular Remodeling with Erythropoietin after Large Myocardial Infarction (REVEAL) trial. AMERICAN HEART JOURNAL, 160(5), 795-U39.

Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome
Becker, R. C., Alexander, J. H., Newby, L. K., Yang, H., Barrett, Y., & Wallentin, L. C. (2010). Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome. THROMBOSIS AND HAEMOSTASIS, 104(5), 976-983.

Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease
White, H., Held, C., Stewart, R., Watson, D., Harrington, R., & Wallentin, L. (2010). Study design and rationale for the clinical outcomes of the STABILITY Trial (STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY) comparing darapladib versus placebo in patients with coronary heart disease. AMERICAN HEART JOURNAL, 160(4), 655-U289.

Ticagrelor Versus Clopidogrel in Acute Coronary Syndromes in Relation to Renal Function Results From the Platelet Inhibition and Patient Outcomes (PLATO) Trial
James, S., Budaj, A., Aylward, P., Buck, K. K., Cannon, C. P., & Wallentin, L. (2010). Ticagrelor Versus Clopidogrel in Acute Coronary Syndromes in Relation to Renal Function Results From the Platelet Inhibition and Patient Outcomes (PLATO) Trial. CIRCULATION, 122(11), 1056-1067.

President's page: the ACC reconfirms commitment to transparent relationships with industry.
Brindis, R., & Harrington, R. (2010). President's page: the ACC reconfirms commitment to transparent relationships with industry. Journal of the American College of Cardiology, 56(11), 900-902.

First Clinical Application of an Actively Reversible Direct Factor IXa Inhibitor as an Anticoagulation Strategy in Patients Undergoing Percutaneous Coronary Intervention
Cohen, M. G., Purdy, D. A., Rossi, J. S., Grinfeld, L. R., Myles, S. K., & Becker, R. C. (2010). First Clinical Application of an Actively Reversible Direct Factor IXa Inhibitor as an Anticoagulation Strategy in Patients Undergoing Percutaneous Coronary Intervention. CIRCULATION, 122(6), 614-622.

Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y(12)-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI)
Leonardi, S., Rao, S. V., Harrington, R. A., Bhatt, D. L., Gibson, C. M., & Welsh, R. C. (2010). Rationale and design of the randomized, double-blind trial testing INtraveNous and Oral administration of elinogrel, a selective and reversible P2Y(12)-receptor inhibitor, versus clopidogrel to eVAluate Tolerability and Efficacy in nonurgent Percutaneous Coronary Interventions patients (INNOVATE-PCI). AMERICAN HEART JOURNAL, 160(1), 65-72.

Randomized Evaluation of efficacy and safety of ferric carboxymaltose in Patients with iron deficiency Anaemia and Impaired Renal function (REPAIR-IDA): rationale and study design
Szczech, L. A., Bregman, D. B., Harrington, R. A., Morris, D., Butcher, A., & Onken, J. E. (2010). Randomized Evaluation of efficacy and safety of ferric carboxymaltose in Patients with iron deficiency Anaemia and Impaired Renal function (REPAIR-IDA): rationale and study design. NEPHROLOGY DIALYSIS TRANSPLANTATION, 25(7), 2368-2375.

There Is a Role for Industry-Sponsored Education in Cardiology
Harrington, R. A., & Califf, R. M. (2010). There Is a Role for Industry-Sponsored Education in Cardiology. CIRCULATION, 121(20), 2221-2227.

An update on the IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design
Califf, R. M., Lokhnygina, Y., Cannon, C. P., Stepanavage, M. E., McCabe, C. H., & Braunwald, E. (2010). An update on the IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) design. AMERICAN HEART JOURNAL, 159(5), 705-709.

Changes in Inflammatory Biomarkers in Patients Treated With Ticagrelor or Clopidogrel
Husted, S., Storey, R. F., Harrington, R. A., Emanuelsson, H., & Cannon, C. P. (2010). Changes in Inflammatory Biomarkers in Patients Treated With Ticagrelor or Clopidogrel. CLINICAL CARDIOLOGY, 33(4), 206-212.

Towards a new order in cardiovascular medicine: re-engineering through global collaboration
Califf, R. M., Armstrong, P. W., Granger, C. B., Harrington, R. A., Lee, K., & White, H. D. (2010). Towards a new order in cardiovascular medicine: re-engineering through global collaboration. EUROPEAN HEART JOURNAL, 31(8), 911-917.

Metabolic Syndrome Is Not Associated With Increased Mortality or Cardiovascular Risk in Nondiabetic Patients With a New Diagnosis of Coronary Artery Disease
Petersen, J. L., Yow, E., Aljaroudi, W., Shaw, L. K., Goyal, A., & Harrington, R. A. (2010). Metabolic Syndrome Is Not Associated With Increased Mortality or Cardiovascular Risk in Nondiabetic Patients With a New Diagnosis of Coronary Artery Disease. CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES, 3(2), 165-172.

Warfarin Use and Outcomes in Patients with Atrial Fibrillation Complicating Acute Coronary Syndromes
Lopes, R. D., Starr, A., Pieper, C. F., Al-Khatib, S. M., Newby, L. K., & Granger, C. B. (2010). Warfarin Use and Outcomes in Patients with Atrial Fibrillation Complicating Acute Coronary Syndromes. AMERICAN JOURNAL OF MEDICINE, 123(2), 134-140.

Comparison of ticagrelor with clopidogrel in patients with planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study
Cannon, C. P., Harrington, R. A., James, S., Ardissino, D., Becker, R. C., & Wallentin, L. (2010). Comparison of ticagrelor with clopidogrel in patients with planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study. LANCET, 375(9711), 283-293.

Intravenous Platelet Blockade with Cangrelor during PCI.
Bhatt, D. L., Lincoff, A. M., Gibson, C. M., Stone, G. W., McNulty, S., & Harrington, R. A. (2009). Intravenous Platelet Blockade with Cangrelor during PCI. NEW ENGLAND JOURNAL OF MEDICINE, 361(24), 2330-2341.

Platelet Inhibition with Cangrelor in Patients Undergoing PCI.
Harrington, R. A., Stone, G. W., McNulty, S., White, H. D., Lincoff, A. M., & Bhatt, D. L. (2009). Platelet Inhibition with Cangrelor in Patients Undergoing PCI. NEW ENGLAND JOURNAL OF MEDICINE, 361(24), 2318-2329.

Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous intervention in patients with ST-elevation myocardial infarction: The Early Rapid ReversAl of Platelet ThromboSis with Intravenous Elinogrel before PCI to Optimize REperfusion in Acute Myocardial Infarction (ERASE MI) pilot trial
Berger, J. S., Roe, M. T., Gibson, C. M., Kilaru, R., Green, C. L., & Armstrong, P. W. (2009). Safety and feasibility of adjunctive antiplatelet therapy with intravenous elinogrel, a direct-acting and reversible P2Y12 ADP-receptor antagonist, before primary percutaneous intervention in patients with ST-elevation myocardial infarction: The Early Rapid ReversAl of Platelet ThromboSis with Intravenous Elinogrel before PCI to Optimize REperfusion in Acute Myocardial Infarction (ERASE MI) pilot trial. AMERICAN HEART JOURNAL, 158(6), 998-U145.

Standardized reporting of bleeding complications for clinical investigations in acute coronary syndromes: A proposal from the Academic Bleeding Consensus (ABC) Multidisciplinary Working Group
Rao, S. V., Eikelboom, J., Steg, P. G., Lincoff, A. M., Weintraub, W. S., & Harrington, R. A. (2009). Standardized reporting of bleeding complications for clinical investigations in acute coronary syndromes: A proposal from the Academic Bleeding Consensus (ABC) Multidisciplinary Working Group. AMERICAN HEART JOURNAL, 158(6), 881-U16.

Comparison of Site-Reported and Core Laboratory-Reported Creatine Kinase-MB Values in Non-ST-Segment Elevation Acute Coronary Syndrome (from the International Trial SYNERGY)
Linefsky, J. P., Lin, M., Pieper, K. S., Reist, C. J., Berdan, L. G., & Mahaffey, K. W. (2009). Comparison of Site-Reported and Core Laboratory-Reported Creatine Kinase-MB Values in Non-ST-Segment Elevation Acute Coronary Syndrome (from the International Trial SYNERGY). AMERICAN JOURNAL OF CARDIOLOGY, 104(10), 1330-1335.

Autologous CD34+Cell Therapy for Refractory Angina: 12 Month Results of the Phase II ACT34-CMI Study
Losordo, D. W., Henry, T., Schatz, R. A., Lee, J. S., Costa, M., & Harrington, R. (2009). Autologous CD34+Cell Therapy for Refractory Angina: 12 Month Results of the Phase II ACT34-CMI Study. CIRCULATION, 120(18), S1132-S1132.

Enoxaparin Versus Unfractionated Heparin in Elective Percutaneous Coronary Intervention 1-Year Results From the STEEPLE (SafeTy and Efficacy of Enoxaparin in Percutaneous coronary intervention patients, an internationaL randomized Evaluation) Trial
Montalescot, G., Gallo, R., White, H. D., Cohen, M., Steg, G., & Steinhubl, S. R. (2009). Enoxaparin Versus Unfractionated Heparin in Elective Percutaneous Coronary Intervention 1-Year Results From the STEEPLE (SafeTy and Efficacy of Enoxaparin in Percutaneous coronary intervention patients, an internationaL randomized Evaluation) Trial. JACC-CARDIOVASCULAR INTERVENTIONS, 2(11), 1083-1091.

Patterns of management of atrial fibrillation complicating coronary artery bypass grafting: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT-IV) Trial
Al-Khatib, S. M., Hafley, G., Harrington, R. A., Mack, M. J., Ferguson, T. B., & Alexander, J. H. (2009). Patterns of management of atrial fibrillation complicating coronary artery bypass grafting: Results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT-IV) Trial. AMERICAN HEART JOURNAL, 158(5), 792-798.

Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs
Chan, M. Y., Weitz, J. I., Merhi, Y., Harrington, R. A., & Becker, R. C. (2009). Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs. JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 28(3), 366-380.

Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes
Wallentin, L., Becker, R. C., Budaj, A., Cannon, C. P., Emanuelsson, H., & Harrington, R. A. (2009). Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes. NEW ENGLAND JOURNAL OF MEDICINE, 361(11), 1045-1057.

Antithrombotics in Acute Coronary Syndromes
Bonaca, M. P., Steg, P. G., Feldman, L. J., Canales, J. F., Ferguson, J. J., & Giugliano, R. P. (2009). Antithrombotics in Acute Coronary Syndromes. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 54(11), 969-984.

Sex Differences in Mortality Following Acute Coronary Syndromes
Berger, J. S., Elliott, L., Gallup, D., Roe, M., Granger, C. B., & Douglas, P. S. (2009). Sex Differences in Mortality Following Acute Coronary Syndromes. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 302(8), 874-882.

Premature Release of Data from Clinical Trials of Ezetimibe
Califf, R. M., Harrington, R. A., & Blazing, M. A. (2009). Premature Release of Data from Clinical Trials of Ezetimibe. NEW ENGLAND JOURNAL OF MEDICINE, 361(7), 712-717.

Endoscopic versus Open Vein-Graft Harvesting in Coronary-Artery Bypass Surgery
Lopes, R. D., Hafley, G. E., Allen, K. B., Ferguson, T. B., Peterson, E. D., & Alexander, J. H. (2009). Endoscopic versus Open Vein-Graft Harvesting in Coronary-Artery Bypass Surgery. NEW ENGLAND JOURNAL OF MEDICINE, 361(3), 235-244.

A new generation of antiplatelet agents
Sellers, M. B., Tricoci, P., & Harrington, R. A. (2009). A new generation of antiplatelet agents. CURRENT OPINION IN CARDIOLOGY, 24(4), 307-312.

Apixaban, an Oral, Direct, Selective Factor Xa Inhibitor, in Combination With Antiplatelet Therapy After Acute Coronary Syndrome Results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) Trial
Alexander, J. H., Becker, R. C., Bhatt, D. L., Cools, F., Crea, F., & Spencer, F. (2009). Apixaban, an Oral, Direct, Selective Factor Xa Inhibitor, in Combination With Antiplatelet Therapy After Acute Coronary Syndrome Results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) Trial. CIRCULATION, 119(22), 2877-U39.

Careers for Clinician Investigators
Harrington, R. A., Califf, R. M., Hodgson, P. K., Peterson, E. D., Roe, M. T., & Mark, D. B. (2009). Careers for Clinician Investigators. CIRCULATION, 119(22), 2945-2950.

Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV
Magee, M. J., Alexander, J. H., Hafley, G., Ferguson, T. B., Gibson, C. M., & Mack, M. J. (2008). Coronary artery bypass graft failure after on-pump and off-pump coronary artery bypass: findings from PREVENT IV. ANNALS OF THORACIC SURGERY, 85(2), 494-500.

First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology - A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity
Dyke, C. K., Steinhubl, S. R., Kleiman, N. S., Cannon, R. O., Aberle, L. G., & Rusconi, C. P. (2006). First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology - A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. CIRCULATION, 114(23), 2490-2497.

Impact of internal mammary artery conduit on long-term outcomes after percutaneous intervention of saphenous vein graft
Mehta, R. H., Honeycutt, E., Peterson, E. D., Granger, C. B., Halabi, A. R., & Sketch, M. H. (2006). Impact of internal mammary artery conduit on long-term outcomes after percutaneous intervention of saphenous vein graft. CIRCULATION, 114, I396-I401.

Care of non-ST-segment elevation patients: Insights from the CRUSADE national quality improvement initiative
Ohman, E. M., Roe, M. T., Smith, S. C., Brindis, R. G., Christenson, R. H., & Peterson, E. D. (2004). Care of non-ST-segment elevation patients: Insights from the CRUSADE national quality improvement initiative. AMERICAN HEART JOURNAL, 148(5), S34-S39.

Immediate coronary artery bypass surgery after platelet inhibition with eptifibatide: Results from PURSUIT
Dyke, C. M., Bhatia, D., Lorenz, T. J., Marso, S. P., Tardiff, B. E., & Harrington, R. A. (2000). Immediate coronary artery bypass surgery after platelet inhibition with eptifibatide: Results from PURSUIT. ANNALS OF THORACIC SURGERY, 70(3), 866-871.

Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease
Harrington, R. A., Armstrong, P. W., Graffagnino, C., Van de Werf, F., Kereiakes, D. J., & Topol, E. J. (2000). Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease. CIRCULATION, 102(7), 728-735.

Glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: Pathophysiologic foundation and clinical findings
Kleiman, N. S., Lincoff, A. M., Ohman, E. M., & Harrington, R. A. (1998). Glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: Pathophysiologic foundation and clinical findings. AMERICAN HEART JOURNAL, 136(4), S32-S42.

Relation between inhibition of platelet aggregation and clinical outcomes
Harrington, R. A., Kleiman, N. S., Granger, C. B., Ohman, E. M., & Berkowitz, S. D. (1998). Relation between inhibition of platelet aggregation and clinical outcomes. AMERICAN HEART JOURNAL, 136(4), S43-S50.

Prognostic value of congestive heart failure history in patients undergoing percutaneous coronary interventions
Anderson, R. D., Ohman, E. M., Holmes, D. R., Harrington, R. A., Barsness, G. W., & Califf, R. M. (1998). Prognostic value of congestive heart failure history in patients undergoing percutaneous coronary interventions. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 32(4), 936-941.

Occurrence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularization
Berkowitz, S. D., Sane, D. C., Sigmon, K. N., Shavender, J. H., Harrington, R. A., & Califf, R. M. (1998). Occurrence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularization. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 32(2), 311-319.

Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor
Ohman, E. M., Harrington, R. A., Lincoff, A. M., Kitt, M. M., Kleiman, N. S., & Tcheng, J. E. (1995). Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor. OXFORD UNIV PRESS.