Laurence Katznelson, MD

Neuroendocrinologist, Pituitary tumors neurosurgeon

Professor of Neurosurgery and of Medicine (Endocrinology) at the Stanford University Medical Center, Lucile Salter Packard Children's Hospital and at PAVAHCS

Brain Tumor Center

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-6469
Learn More About the Clinic Getting Here Make An Appointment

Pituitary Center

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-721-1020
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Gastrointestinal (GI) Cancer Program

  • 875 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
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Brain Tumor Center at the Advanced Medicine Center, Clinic D

  • 875 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Residency: Hospital of the University of Pennsylvania (1987) PA

Board Certification: Endocrinology, Diabetes and Metabolism, American Board of Internal Medicine (2013)

Board Certification, Board of Internal Medicine, Endocrinology and Metabolism (1991)

Fellowship: Massachusetts General Hospital (1992) MA

Board Certification: Internal Medicine, American Board of Internal Medicine (1988)

Internship: Hospital of the University of Pennsylvania (1986) PA

Medical Education: UCLA School of Medicine (1985) CA

Endocrinology, Mass. General Hosp, Boston, Endocrinology and Metabolism (1992)

BS, U.C., Berkeley, Genetics (1981)

Honors & Awards

Best Doctors in America, Best Doctors (2005-)

Administrative Appointments

Chair, Special Programs Committee, Endocrine Society (2008 - 2011)

Director, Endocrinology Fellowship Training Program, Stanford (2005 - 2014)

Medical Director, Stanford Pituitary Center (2004 - Present)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Global clinical response in Cushing's syndrome patients treated with mifepristone
Katznelson, L., Loriaux, D. L., Feldman, D., Braunstein, G. D., Schteingart, D. E., & Gross, C. (2014). Global clinical response in Cushing's syndrome patients treated with mifepristone. CLINICAL ENDOCRINOLOGY, 80(4), 562-569.

Clinical characteristics, timing of peak responses and safety aspects of two dosing regimens of the glucagon stimulation test in evaluating growth hormone and cortisol secretion in adults
Yuen, K. Cj., Biller, B. Mk., Katznelson, L., Rhoads, S. A., Gurel, M. H., & Cook, D. M. (2013). Clinical characteristics, timing of peak responses and safety aspects of two dosing regimens of the glucagon stimulation test in evaluating growth hormone and cortisol secretion in adults. PITUITARY, 16(2), 220-230.

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND TREATMENT OF ACROMEGALY-2011 UPDATE: EXECUTIVE SUMMARY
Katznelson, L., Atkinson, J. Ld., Cook, D. M., Ezzat, S. Z., Hamrahian, A. H., & Miller, K. K. (2011). AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND TREATMENT OF ACROMEGALY-2011 UPDATE: EXECUTIVE SUMMARY. ENDOCRINE PRACTICE, 17(4), 636-646.

Pituitary Incidentaloma: An Endocrine Society Clinical Practice Guideline
Freda, P. U., Beckers, A. M., Katznelson, L., Molitch, M. E., Montori, V. M., & Vance, M. L. (2011). Pituitary Incidentaloma: An Endocrine Society Clinical Practice Guideline. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 96(4), 894-904.

Fatigue after traumatic brain injury: Association with neuroendocrine, sleep, depression and other factors
Englander, J., Bushnik, T., Oggins, J., & Katznelson, L. (2010). Fatigue after traumatic brain injury: Association with neuroendocrine, sleep, depression and other factors. BRAIN INJURY, 24(12), 1379-1388.

Fatigue after TBI: Association with neuroendocrine abnormalities
Bushnik, T., Englander, J., & Katznelson, L. (2007). Fatigue after TBI: Association with neuroendocrine abnormalities. BRAIN INJURY, 21(6), 559-566.

Treatments, complications, and healthcare utilization associated with acromegaly: a study in two large United States databases
Broder, M. S., Neary, M. P., Chang, E., Cherepanov, D., & Katznelson, L. (2014). Treatments, complications, and healthcare utilization associated with acromegaly: a study in two large United States databases. PITUITARY, 17(4), 333-341.

CLINICAL CHARACTERISTICS AND PITUITARY DYSFUNCTION IN PATIENTS WITH METASTATIC CANCER TO THE SELLA
Ariel, D., Sung, H., Coghlan, N., Dodd, R., Gibbs, I. C., & Katznelson, L. (2013). CLINICAL CHARACTERISTICS AND PITUITARY DYSFUNCTION IN PATIENTS WITH METASTATIC CANCER TO THE SELLA. ENDOCRINE PRACTICE, 19(6), 914-919.

Sustained Improvements in Plasma ACTH and Clinical Status in a Patient With Nelson's Syndrome Treated With Pasireotide LAR, a Multireceptor Somatostatin Analog
Katznelson, L. (2013). Sustained Improvements in Plasma ACTH and Clinical Status in a Patient With Nelson's Syndrome Treated With Pasireotide LAR, a Multireceptor Somatostatin Analog. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 98(5), 1803-1807.

In Reply: Pituitary Centers of Excellence.
McLaughlin, N., Laws, E. R., Oyesiku, N. M., Katznelson, L., & Kelly, D. F. (2013). In Reply: Pituitary Centers of Excellence. Neurosurgery.

Pituitary Centers of Excellence
McLaughlin, N., Laws, E. R., Oyesiku, N. M., Katznelson, L., & Kelly, D. F. (2012). Pituitary Centers of Excellence. NEUROSURGERY, 71(5), 916-924.

The dynamics of post-operative plasma ACTH values following transsphenoidal surgery for Cushing's disease
Srinivasan, L., Laws, E. R., Dodd, R. L., Monita, M. M., Tannenbaum, C. E., & Katznelson, L. (2011). The dynamics of post-operative plasma ACTH values following transsphenoidal surgery for Cushing's disease. PITUITARY, 14(4), 312-317.

American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly--2011 update.
Katznelson, L., Atkinson, J. Ld., Cook, D. M., Ezzat, S. Z., Hamrahian, A. H., & Miller, K. K. (2011). American Association of Clinical Endocrinologists medical guidelines for clinical practice for the diagnosis and treatment of acromegaly--2011 update. Endocrine practice , 17, 1-44.

ECTOPIC ACROMEGALY DUE TO A PANCREATIC NEUROENDOCRINE TUMOR PRODUCING GROWTH HORMONE-RELEASING HORMONE
Weiss, D. E., Vogel, H., Lopes, M. B. S., Chang, S. D., & Katznelson, L. (2011). ECTOPIC ACROMEGALY DUE TO A PANCREATIC NEUROENDOCRINE TUMOR PRODUCING GROWTH HORMONE-RELEASING HORMONE. ENDOCRINE PRACTICE, 17(1), 79-84.

Retrosellar intracranial extracerebral glioneuronal heterotopion: case report
Karamchandani, J., Fischbein, N., Harsh, G., Katznelson, L., & Vogel, H. (2010). Retrosellar intracranial extracerebral glioneuronal heterotopion: case report. CLINICAL NEUROPATHOLOGY, 29(5), 297-300.

Approach to the Patient with Persistent Acromegaly after Pituitary Surgery
Katznelson, L. (2010). Approach to the Patient with Persistent Acromegaly after Pituitary Surgery. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 95(9), 4114-4123.

A NOVEL PRKAR1A MUTATION ASSOCIATED WITH PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE AND THE CARNEY COMPLEX
Peck, M. C., Visser, B. C., Norton, J. A., Pasche, L., & Katznelson, L. (2010). A NOVEL PRKAR1A MUTATION ASSOCIATED WITH PRIMARY PIGMENTED NODULAR ADRENOCORTICAL DISEASE AND THE CARNEY COMPLEX. ENDOCRINE PRACTICE, 16(2), 198-204.

Prevalence and clinical demographics of cerebral salt wasting in patients with aneurysmal subarachnoid hemorrhage
Kao, L., Al-Lawati, Z., Vavao, J., Steinberg, G. K., & Katznelson, L. (2009). Prevalence and clinical demographics of cerebral salt wasting in patients with aneurysmal subarachnoid hemorrhage. PITUITARY, 12(4), 347-351.

Lanreotide promotes apoptosis and is not radioprotective in GH3 cells
Ning, S., Knox, S. J., Harsh, G. R., Culler, M. D., & Katznelson, L. (2009). Lanreotide promotes apoptosis and is not radioprotective in GH3 cells. ENDOCRINE-RELATED CANCER, 16(3), 1045-1055.

Non-surgical management of hormone-secreting pituitary tumors
Patil, C. G., Hayden, M., Katznelson, L., & Chang, S. D. (2009). Non-surgical management of hormone-secreting pituitary tumors. JOURNAL OF CLINICAL NEUROSCIENCE, 16(8), 985-993.

The impact of hypopituitarism on function and performance in subjects with recent history of traumatic brain injury and aneurysmal subarachnoid haemorrhage.
Srinivasan, L., Roberts, B., Bushnik, T., Englander, J., Spain, D. A., & Katznelson, L. (2009). The impact of hypopituitarism on function and performance in subjects with recent history of traumatic brain injury and aneurysmal subarachnoid haemorrhage. Brain injury , 23(7), 639-648.

Alterations in body composition in acromegaly
Katznelson, L. (2009). Alterations in body composition in acromegaly. PITUITARY, 12(2), 136-142.

Endogenous NIS Expression in Triple-Negative Breast Cancers
Renier, C., Yao, C., Goris, M., Ghosh, M., Katznelson, L., & Wapnir, I. (2009). Endogenous NIS Expression in Triple-Negative Breast Cancers. ANNALS OF SURGICAL ONCOLOGY, 16(4), 962-968.

Use of high-dose oral bisphosphonate therapy for symptomatic fibrous dysplasia of the skull
Chao, K., & Katznelson, L. (2008). Use of high-dose oral bisphosphonate therapy for symptomatic fibrous dysplasia of the skull. JOURNAL OF NEUROSURGERY, 109(5), 889-892.

An update on treatment strategies for acromegaly
Katznelson, L. (2008). An update on treatment strategies for acromegaly. EXPERT OPINION ON PHARMACOTHERAPY, 9(13), 2273-2280.

Outcomes after repeat transsphenoidal surgery for recurrent Cushing's disease
Patil, C. G., Veeravagu, A., Prevedello, D. A., Katznelson, L., Vance, M. L., & Cappabianca, P. (2008). Outcomes after repeat transsphenoidal surgery for recurrent Cushing's disease. NEUROSURGERY, 63(2), 266-271.

Late recurrences of Cushing's disease after initial successful transsphenoidal surgery
Patil, C. G., Prevedello, D. M., Lad, S. P., Vance, M. L., Thorner, M. O., & Laws, E. R. (2008). Late recurrences of Cushing's disease after initial successful transsphenoidal surgery. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 93(2), 358-362.

Reninoma: case report and literature review
Wonga, L., Hsu, T. Hs., Perlroth, M. G., Hofmann, L. V., Haynes, C. M., & Katznelson, L. (2008). Reninoma: case report and literature review. JOURNAL OF HYPERTENSION, 26(2), 368-373.

Current thinking on the management of the acromegalic patient.
Katznelson, L. (2007). Current thinking on the management of the acromegalic patient. Current opinion in endocrinology, diabetes, and obesity, 14(4), 311-316.

Pegvisomant for the treatment of acromegaly-translation of clinical trials into clinical practice
Katznelson, L. (2007). Pegvisomant for the treatment of acromegaly-translation of clinical trials into clinical practice. NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM, 3(7), 514-515.

Approach to the evaluation of the GH/IGF-axis in patients with pituitary disease: Which test to order
Roberts, B., & Katznelson, L. (2007). Approach to the evaluation of the GH/IGF-axis in patients with pituitary disease: Which test to order. PITUITARY, 10(2), 205-211.

The role of inferior petrosal sinus sampling in the diagnostic localization of Cushing's disease.
Lad, S. P., Patil, C. G., Laws, E. R., & Katznelson, L. (2007). The role of inferior petrosal sinus sampling in the diagnostic localization of Cushing's disease. Neurosurgical focus, 23(3), E2-?.

Brain atrophy and cognitive deficits in Cushing's disease.
Patil, C. G., Lad, S. P., Katznelson, L., & Laws, E. R. (2007). Brain atrophy and cognitive deficits in Cushing's disease. Neurosurgical focus, 23(3), E11-?.

Efficacy and safety of CyberKnife radiosurgery for acromegaly.
Roberts, B. K., Ouyang, D. L., Lad, S. P., Chang, S. D., Harsh, G. R., & Katznelson, L. (2007). Efficacy and safety of CyberKnife radiosurgery for acromegaly. Pituitary, 10(1), 19-25.

Effects of modest testosterone supplementation and exercise for 12 weeks on body composition and quality of life in elderly men
Katznelson, L., Robinson, M. W., Coyle, C. L., Lee, H., & Farrell, C. E. (2006). Effects of modest testosterone supplementation and exercise for 12 weeks on body composition and quality of life in elderly men. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 155(6), 867-875.

Isolated Langerhans cell histiocytosis in an adult with central diabetes insipidus: case report and review of literature.
Ouyang, D. L., Roberts, B. K., Gibbs, I. C., & Katznelson, L. (2006). Isolated Langerhans cell histiocytosis in an adult with central diabetes insipidus: case report and review of literature. Endocrine practice , 12(6), 660-663.

Drug Insight: primary medical therapy of acromegaly
Katznelson, L. (2006). Drug Insight: primary medical therapy of acromegaly. NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM, 2(2), 109-117.

Long-acting somatostatin analog therapy of acromegaly: A meta- analysis
Freda, P. U., Katznelson, L., van der Lely, A. J., Reyes, C. M., Zhao, S. H., & Rabinowitz, D. (2005). Long-acting somatostatin analog therapy of acromegaly: A meta- analysis. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 90(8), 4465-4473.

Diagnosis and treatment of acromegaly
Katznelson, L. (2005). Diagnosis and treatment of acromegaly. GROWTH HORMONE & IGF RESEARCH, 15, S31-S35.

Diagnostic errors after inferior petrosal sinus sampling
Swearingen, B., Katznelson, L., Miller, K., Grinspoon, S., Waltman, A., & Biller, B. Mk. (2004). Diagnostic errors after inferior petrosal sinus sampling. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 89(8), 3752-3763.

Effects of growth hormone secretion on body composition in patients with Crohn's disease
Katznelson, L., Fairfield, W. P., Zeizafoun, N., Sands, B. E., Peppercorn, M. A., & Klibanski, A. (2003). Effects of growth hormone secretion on body composition in patients with Crohn's disease. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(11), 5468-5472.

Cardiovascular risk factors in acromegaly before and after normalization of serum IGF-I levels with the GH antagonist pegvisomant
Sesmilo, G., Fairfield, W. P., Katznelson, L., Pulaski, K., Freda, P. U., & Klibanski, A. (2002). Cardiovascular risk factors in acromegaly before and after normalization of serum IGF-I levels with the GH antagonist pegvisomant. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 87(4), 1692-1699.

Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist
van der Lely, A. J., Hutson, R. K., Trainer, P. J., Besser, G. M., Barkan, A. L., & Thorner, M. (2001). Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. LANCET, 358(9295), 1754-1759.

Somatostatin receptor-specific analogs: Effects on cell proliferation and growth hormone secretion in human somatotroph tumors
Danila, D. C., Haidar, J. Ns., Zhang, X., Katznelson, L., Culler, M. D., & Klibanski, A. (2001). Somatostatin receptor-specific analogs: Effects on cell proliferation and growth hormone secretion in human somatotroph tumors. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 86(7), 2976-2981.

Hypothalamic/pituitary function following high-dose conformal radiotherapy to the base of skull: Demonstration of a dose-effect relationship using dose-volume histogram analysis
Pai, H. H., Thornton, A., Katznelson, L., Finkelstein, D. M., Adams, J. A., & Munzenrider, J. E. (2001). Hypothalamic/pituitary function following high-dose conformal radiotherapy to the base of skull: Demonstration of a dose-effect relationship using dose-volume histogram analysis. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 49(4), 1079-1092.

Hypogonadism in patients with acromegaly: data from the multi-centre acromegaly registry pilot study
Katznelson, L., Kleinberg, D., Vance, M. L., Stravou, S., Pulaski, K. J., & Klibanski, A. (2001). Hypogonadism in patients with acromegaly: data from the multi-centre acromegaly registry pilot study. CLINICAL ENDOCRINOLOGY, 54(2), 183-188.

Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant
Trainer, P. J., Drake, W. M., Katznelson, L., Freda, P. U., Herman-Bonert, V., & Davis, R. J. (2000). Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. NEW ENGLAND JOURNAL OF MEDICINE, 342(16), 1171-1177.

Biochemical assessment of Cushing's disease in patients with corticotroph macroadenomas
Katznelson, L., Bogan, J. S., Trob, J. R., Schoenfeld, D. A., Hedley-Whyte, E. T., & Klibanski, A. (1998). Biochemical assessment of Cushing's disease in patients with corticotroph macroadenomas. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 83(5), 1619-1623.