Michael J. Kaplan

Head and neck surgical oncologist, Surgical oncologist, Head and neck surgeon, Otolaryngologist

Professor of Otolaryngology - Head and Neck Surgery and, by courtesy, of Neurosurgery at the Stanford University Medical Center

Head and Neck Cancer Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

Cranial Base Center

  • 801 Welch Road
  • Stanford, CA 94305
  • Phone: 650-723-5281
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Professional Education

Internship: Beth Israel Deaconess Medical Center (1978) MA

Fellowship: University of Virginia (1984) VA

Board Certification: Otolaryngology, American Board of Otolaryngology (1982)

Residency: Massachusetts Eye and Ear Infirmary (1982) MA

Residency: Beth Israel and Children's Hospital (1979) MA

Medical Education: Harvard Medical School (1977) MA

Fellowship, University of Virginia, Head & Neck; Skull Base Surgery (1984)

Residency, Massachusetts Eye & Ear, Otolaryngology-Head & Neck Surgery (1982)

MD, Harvard Medical School (1977)

BA, Harvard College, Molecular Biology (1973)

Honors & Awards

Best Doctors in America, . (1998-2012)

Chief Residents' Special Certificate of Merit, UCSF (1993)

Roger Boles Teaching award, UCSF (1987)

Phi Beta Kappa, Harvard College (1973)

Administrative Appointments

Head & Neck Oncology Program, Disease Management Leader, Stanford Cancer Center (2010 - Present)

Chief, Head & Neck Surgery, Otolaryngology-Head&Neck Surgery (2003 - Present)

Head & Neck Fellowship Director, Otolaryngology-Head&Neck Surgery (2003 - Present)

Long-term outcomes of surgery followed by radiation therapy for minor salivary gland carcinomas.
Zeidan, Y. H., Shultz, D. B., Murphy, J. D., An, Y., Chan, C., & Le, Q.-T. (2013). Long-term outcomes of surgery followed by radiation therapy for minor salivary gland carcinomas. Laryngoscope, 123(11), 2675-2680.

Radiotherapy for nonadenoid cystic carcinomas of major salivary glands
Chung, M. P., Tang, C., Chan, C., Hara, W. Y., Loo, B. W., & Chang, D. T. (2013). Radiotherapy for nonadenoid cystic carcinomas of major salivary glands. AMERICAN JOURNAL OF OTOLARYNGOLOGY, 34(5), 425-430.

Stereotactic Radiosurgery for Retreatment of Gross Perineural Invasion in Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck
Tang, C., Fischbein, N. J., Murphy, J. D., Chu, K. P., Bavan, B., & Quynh-Thu Le, Q. T. (2013). Stereotactic Radiosurgery for Retreatment of Gross Perineural Invasion in Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 36(3), 293-298.

Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence
Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., & Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. CANCER, 119(7), 1349-1356.

CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma
Janisiewicz, A. M., Shin, J. H., Murillo-Sauca, O., Kwok, S., Quynh-Thu Le, Q. T., & Sunwoo, J. B. (2012). CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(6), 465-470.

Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure
Wiegner, E. A., Daly, M. E., Murphy, J. D., Abelson, J., Chapman, C. H., & Chang, D. T. (2012). Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(1), 243-251.

Targeted endoscopic salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma
Ho, A. S., Kaplan, M. J., Fee, W. E., Yao, M., Sunwoo, J. B., & Hwang, P. H. (2012). Targeted endoscopic salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(2), 166-173.

FREQUENCY OF CELLS EXPRESSING CD44, A HEAD AND NECK CANCER STEM CELL MARKER: CORRELATION WITH TUMOR AGGRESSIVENESS
Joshua, B., Kaplan, M. J., Doweck, I., Pai, R., Weissman, I. L., & Ailles, L. E. (2012). FREQUENCY OF CELLS EXPRESSING CD44, A HEAD AND NECK CANCER STEM CELL MARKER: CORRELATION WITH TUMOR AGGRESSIVENESS. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 34(1), 42-49.

A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo
Banh, A., Xiao, N., Cao, H., Chen, C.-H., Kuo, P., & Quynh-Thu Le, Q. T. (2011). A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo. CLINICAL CANCER RESEARCH, 17(23), 7265-7272.

Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity
Murphy, J. D., Chisholm, K. M., Daly, M. E., Wiegner, E. A., Truong, D., & Le, Q.-T. (2011). Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity. RADIOTHERAPY AND ONCOLOGY, 101(3), 356-361.

INTENSITY-MODULATED RADIOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA: PATTERNS OF FAILURE AND PREDICTORS OF LOCAL CONTROL
Daly, M. E., Quynh-Thu Le, Q. T., Kozak, M. M., Maxim, P. G., Murphy, J. D., & Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA: PATTERNS OF FAILURE AND PREDICTORS OF LOCAL CONTROL. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 80(5), 1412-1422.

INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX
Daly, M. E., Le, Q.-T., Jain, A. K., Maxim, P. G., Hsu, A., & Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 33(1), 103-111.

Transoral Robotic Surgery (TORS): The Natural Evolution of Endoscopic Head and Neck Surgery KAPLAN ARTICLE REVIEWED
Kaplan, M. J., & Damrose, E. J. (2010). Transoral Robotic Surgery (TORS): The Natural Evolution of Endoscopic Head and Neck Surgery KAPLAN ARTICLE REVIEWED. ONCOLOGY-NEW YORK, 24(11), 1022-1030.

HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA
Filion, E. J., McClure, L. A., Huang, D., Seng, K., Kaplan, M. J., & Le, Q.-T. (2010). HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 32(10), 1336-1344.

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
Boiko, A. D., Razorenova, O. V., van de Rijn, M., Swetter, S. M., Johnson, D. L., & Weissman, I. L. (2010). Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. NATURE, 466(7302), 133-U155.

INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF OROPHARYNGEAL CANCER: CLINICAL OUTCOMES AND PATTERNS OF FAILURE
Daly, M. E., Le, Q.-T., Maxim, P. G., Loo, B. W., Kaplan, M. J., & Chang, D. T. (2010). INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF OROPHARYNGEAL CANCER: CLINICAL OUTCOMES AND PATTERNS OF FAILURE. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 76(5), 1339-1346.

Metastatic Squamous Cell Carcinoma Presenting as Diffuse and Punctate Cervical Lymph Node Calcifications Sonographic Features and Utility of Sonographically Guided Fine-Needle Aspiration Biopsy
Shin, L. K., Fischbein, N. J., Kaplan, M. J., & Jeffrey, R. B. (2009). Metastatic Squamous Cell Carcinoma Presenting as Diffuse and Punctate Cervical Lymph Node Calcifications Sonographic Features and Utility of Sonographically Guided Fine-Needle Aspiration Biopsy. JOURNAL OF ULTRASOUND IN MEDICINE, 28(12), 1703-1707.

Association of reactive oxygen species levels and radioresistance in cancer stem cells
Diehn, M., Cho, R. W., Lobo, N. A., Kalisky, T., Dorie, M. J., & Clarke, M. F. (2009). Association of reactive oxygen species levels and radioresistance in cancer stem cells. NATURE, 458(7239), 780-U123.

Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma
Hara, W., Loo, B. W., Goffinet, D. R., Chang, S. D., Adler, J. R., & Le, Q.-T. (2008). Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 71(2), 393-400.

Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma
Daly, M. E., Lieskovsky, Yy., Pawlicki, T., Yau, J., Pinto, H., & Le, Q.-T. (2007). Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 29(3), 211-220.

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
Prince, M. E., Sivanandan, R., Kaczorowski, A., Wolf, G. T., Kaplan, M. J., & Ailles, L. E. (2007). Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(3), 973-978.

Clinical role of F-18-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma
Quon, A., Fischbein, N. J., McDougall, I. R., Le, Q.-T., Loo, B. W., & Kaplan, M. J. (2007). Clinical role of F-18-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma. JOURNAL OF NUCLEAR MEDICINE, 48, 58S-67S.

Plasma osteopontin is an independent prognostic marker for head and neck cancers
Petrik, D., Lavori, P. W., Cao, H., Zhu, Y., Wong, P., & Le, Q.-T. (2006). Plasma osteopontin is an independent prognostic marker for head and neck cancers. JOURNAL OF CLINICAL ONCOLOGY, 24(33), 5291-5297.

Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site
Shirazi, H. A., Sivanandan, R., Goode, R., Fee, W. E., Kaplan, M. J., & Le, Q.-T. (2006). Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 28(7), 587-594.

Anterior skull base surgery
Kaplan, M. J., Fischbein, N. J., & Harsh, G. R. (2005). Anterior skull base surgery. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA, 38(1), 107-?.

Long-term results of 100 consecutive comprehensive neck dissections - Implications for selective neck dissections
Sivanandan, R., Kaplan, M. J., Lee, K. J., Lebl, D., PINTO, H., & Fee, W. E. (2004). Long-term results of 100 consecutive comprehensive neck dissections - Implications for selective neck dissections. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 130(12), 1369-1373.

Laryngeal embryonal rhabdomyosarcoma - A case of cervical metastases 13 years after treatment and a 25-year review of existing literature
Sivanandan, R., Kong, C. S., Kaplan, M. J., Fee, W. E., Thu-Le, Q., & Goffnet, D. R. (2004). Laryngeal embryonal rhabdomyosarcoma - A case of cervical metastases 13 years after treatment and a 25-year review of existing literature. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 130(10), 1217-1222.

Lymph node metastasis in maxillary sinus carcinoma
Le, Q. T., Fu, K. K., Kaplan, M. J., Terris, D. J., Fee, W. E., & Goffinet, D. R. (2000). Lymph node metastasis in maxillary sinus carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(3), 541-549.

Treatment of maxillary sinus carcinoma - A comparison of the 1997 and 1977 American Joint Committee on Cancer staging systems
Le, Q. T., Fu, K. K., Kaplan, M., Terris, D. J., Fee, W. E., & Goffinet, D. R. (1999). Treatment of maxillary sinus carcinoma - A comparison of the 1997 and 1977 American Joint Committee on Cancer staging systems. CANCER, 86(9), 1700-1711.

Magnetic resonance imaging of the central skull base.
Fischbein, N. J., & Kaplan, M. J. (1999). Magnetic resonance imaging of the central skull base. Topics in magnetic resonance imaging , 10(5), 325-346.