Paul A. Khavari, MD, PhD

Dermatologist

Cutaneous oncology specialist, Medical oncologist
Dr. Khavari only sees U.S. veteran patients at the VA Palo Alto Healthcare System

Professional Education

Internship: Yale-New Haven Hospital (1989) CT

Medical Education: Yale University School of Medicine (1988) CT

Fellowship: Stanford University School of Medicine (1994) CA

Residency: Stanford University School of Medicine (1991) CA

Board Certification: Dermatology, American Board of Dermatology (1992)

Residency: Yale - New Haven Hospital (1990) CT

Administrative Appointments

Co-Director, Stanford Program in Epithelial Biology, 1999

Chair Department of Dermatology, Stanford University School of Medicine, 2010

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
Jameson, K. L., Mazur, P. K., Zehnder, A. M., Zhang, J., Zarnegar, B., & Khavari, P. A. (2013). IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nature medicine, 19(5), 626-630.

ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4.
Bao, X., Tang, J., Lopez-Pajares, V., Tao, S., Qu, K., & Khavari, P. A. (2013). ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4. Cell stem cell, 12(2), 193-203.

Control of somatic tissue differentiation by the long non-coding RNA TINCR
Kretz, M., Siprashvili, Z., Chu, C., Webster, D. E., Zehnder, A., & Khavari, P. A. (2013). Control of somatic tissue differentiation by the long non-coding RNA TINCR. NATURE, 493(7431), 231-U245.

ZNF750 Is a p63 Target Gene that Induces KLF4 to Drive Terminal Epidermal Differentiation
Sen, G. L., Boxer, L. D., Webster, D. E., Bussat, R. T., Qu, K., & Khavari, P. A. (2012). ZNF750 Is a p63 Target Gene that Induces KLF4 to Drive Terminal Epidermal Differentiation. DEVELOPMENTAL CELL, 22(3), 669-677.

DNMT1 maintains progenitor function in self-renewing somatic tissue
Sen, G. L., Reuter, J. A., Webster, D. E., Zhu, L., & Khavari, P. A. (2010). DNMT1 maintains progenitor function in self-renewing somatic tissue. NATURE, 463(7280), 563-U189.

Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia
Ridky TW, & Khavari PA. (2010). Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia. Nature Medicine, 16.

Modeling Inducible Human Tissue Neoplasia Identifies an Extracellular Matrix Interaction Network Involved in Cancer Progression
Reuter, J. A., Ortiz-Urda, S., Kretz, M., Garcia, J., Scholl, F. A., & Khavari, P. A. (2009). Modeling Inducible Human Tissue Neoplasia Identifies an Extracellular Matrix Interaction Network Involved in Cancer Progression. CANCER CELL, 15(6), 477-488.

Use of human tissue to assess the oncogenic activity of melanoma-associated mutations
Chudnovsky, Y., Adams, A. E., Robbins, P. B., Lin, Q., & Khavari, P. A. (2005). Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. NATURE GENETICS, 37(7), 745-749.

Type VII collagen is required for Ras-driven human epidermal tumorigenesis
Ortiz-Urda, S., Garcia, J., Green, C. L., Chen, L., Lin, Q., & Khavari, P. A. (2005). Type VII collagen is required for Ras-driven human epidermal tumorigenesis. SCIENCE, 307(5716), 1773-1776.

NF-kappa B blockade and oncogenic Ras trigger invasive human epidermal neoplasia
Dajee, M., Lazarov, M., Zhang, J. Y., Cai, T., Green, C. L., & Khavari, P. A. (2003). NF-kappa B blockade and oncogenic Ras trigger invasive human epidermal neoplasia. NATURE, 421(6923), 639-643.

CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis
Lazarov, M., Kubo, Y., Cai, T., Dajee, M., Tarutani, M., & Khavari, P. A. (2002). CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis. NATURE MEDICINE, 8(10), 1105-1114.

Stable nonviral genetic correction of inherited human skin disease
Ortiz-Urda, S., Thyagarajan, B., Keene, D. R., Lin, Q., Fang, M., & Khavari, P. A. (2002). Stable nonviral genetic correction of inherited human skin disease. NATURE MEDICINE, 8(10), 1166-1170.

Stable nonviral genetic correction of inherited human skin disease
Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Fang M, & Khavari PA. (2002). Stable nonviral genetic correction of inherited human skin disease. Nature Medicine, 8.

Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation
Rothbard, J. B., Garlington, S., Lin, Q., Kirschberg, T., Kreider, E., & Khavari, P. A. (2000). Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation. NATURE MEDICINE, 6(11), 1253-1257.

Immunization via hair follicles by topical application of naked DNA to normal skin
Fan, H. R., Lin, Q., Morrissey, G. R., & Khavari, P. A. (1999). Immunization via hair follicles by topical application of naked DNA to normal skin. NATURE BIOTECHNOLOGY, 17(9), 870-872.

Sustainable cutaneous gene delivery
Deng, H., Lin, Q., & Khavari, P. A. (1997). Sustainable cutaneous gene delivery. NATURE BIOTECHNOLOGY, 15(13), 1388-1391.

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog
Fan, H. R., Oro, A. E., Scott, M. P., & Khavari, P. A. (1997). Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. NATURE MEDICINE, 3(7), 788-792.

Gene therapy: Progress, problems, prospects.
Blau, H., & Khavari, P. (1997). Gene therapy: Progress, problems, prospects. NATURE MEDICINE, 3(6), 612-613.

Corrective gene transfer in the human skin disorder lamellar ichthyosis
Choate, K. A., Medalie, D. A., Morgan, J. R., & Khavari, P. A. (1996). Corrective gene transfer in the human skin disorder lamellar ichthyosis. NATURE MEDICINE, 2(11), 1263-1267.

THE RETINOBLASTOMA PROTEIN AND BRG1 FORM A COMPLEX AND COOPERATE TO INDUCE CELL-CYCLE ARREST
Dunaief, J. L., Strober, B. E., Guha, S., Khavari, P. A., Alin, K., & Goff, S. P. (1994). THE RETINOBLASTOMA PROTEIN AND BRG1 FORM A COMPLEX AND COOPERATE TO INDUCE CELL-CYCLE ARREST. CELL, 79(1), 119-130.

NUCLEOSOME DISRUPTION AND ENHANCEMENT OF ACTIVATOR BINDING BY A HUMAN SW1/SNF COMPLEX
Kwon, H., Imbalzano, A. N., Khavari, P. A., Kingston, R. E., & GREEN, M. R. (1994). NUCLEOSOME DISRUPTION AND ENHANCEMENT OF ACTIVATOR BINDING BY A HUMAN SW1/SNF COMPLEX. NATURE, 370(6489), 477-481.

BRG1 CONTAINS A CONSERVED DOMAIN OF THE SWI2/SNF2 FAMILY NECESSARY FOR NORMAL MITOTIC GROWTH AND TRANSCRIPTION
Khavari, P. A., Peterson, C. L., Tamkun, J. W., Mendel, D. B., & Crabtree, G. R. (1993). BRG1 CONTAINS A CONSERVED DOMAIN OF THE SWI2/SNF2 FAMILY NECESSARY FOR NORMAL MITOTIC GROWTH AND TRANSCRIPTION. NATURE, 366(6451), 170-174.

CHARACTERIZATION OF A COFACTOR THAT REGULATES DIMERIZATION OF A MAMMALIAN HOMEODOMAIN PROTEIN
Mendel, D. B., Khavari, P. A., Conley, P. B., Graves, M. K., Hansen, L. P., & Crabtree, G. R. (1991). CHARACTERIZATION OF A COFACTOR THAT REGULATES DIMERIZATION OF A MAMMALIAN HOMEODOMAIN PROTEIN. SCIENCE, 254(5039), 1762-1767.