Peter Kao

Pulmonologist

Associate Professor of Medicine (Pulmonary and Critical Care Medicine)

Chest Clinic

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-725-7061
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Professional Education

Medical Education: Columbia University College of Physicians and Surgeons (1988) NJ

Fellowship: Stanford University School of Medicine (1992) CA

Residency: Stanford University School of Medicine (1990) CA

Internship: Stanford University School of Medicine (1989) CA

Board Certification: Pulmonary Disease, American Board of Internal Medicine (1994)

Board Certification: Critical Care Medicine, American Board of Internal Medicine (1995)

A.B.-A.M., Harvard University, Chemistry and Physics (1979)

Ph.D., Columbia University, Biochemistry (1986)

M.D., Columbia University P&S, Medicine (1988)

NF90 regulates inducible IL-2 gene expression in T cells
Shi, L., Godfrey, W. R., Lin, J., Zhao, G., & Kao, P. N. (2007). NF90 regulates inducible IL-2 gene expression in T cells. JOURNAL OF EXPERIMENTAL MEDICINE, 204(5), 971-977.

Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells
Shi, L., Qiu, D., Zhao, G., Corthesy, B., Lees-Miller, S., & Kao, P. N. (2007). Dynamic binding of Ku80, Ku70 and NF90 to the IL-2 promoter in vivo in activated T-cells. NUCLEIC ACIDS RESEARCH, 35(7), 2302-2310.

Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo
Nishimura, T., Myles, T., Piliposky, A. M., Kao, P. N., Berry, G. J., & Leung, L. Lk. (2007). Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo. BLOOD, 109(5), 1992-1997.

Aerosolized amikacin for treatment of pulmonary Mycobacterium avium infections: an observational case series.
Davis, K. K., Kao, P. N., Jacobs, S. S., & Ruoss, S. J. (2007). Aerosolized amikacin for treatment of pulmonary Mycobacterium avium infections: an observational case series. BMC pulmonary medicine, 7, 2-?.

Prospective analysis of cystic fibrosis transmembrane regulator mutations in adults with bronchiectasis or pulmonary nontuberculous mycobacterial infection
Ziedalski, T. M., Kao, P. N., Henig, N. R., Jacobs, S. S., & Ruoss, S. J. (2006). Prospective analysis of cystic fibrosis transmembrane regulator mutations in adults with bronchiectasis or pulmonary nontuberculous mycobacterial infection. CHEST, 130(4), 995-1002.

Simvastatin enhances bone morphogenetic protein receptor type II expression
Hu, H., Sung, A., Zhao, G. H., Shi, L. F., Qiu, D. M., & Kao, P. N. (2006). Simvastatin enhances bone morphogenetic protein receptor type II expression. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 339(1), 59-64.

Lung surfactant gelation induced by epithelial cells exposed to air pollution or oxidative stress
Anseth, J. W., Goffin, A. J., Fuller, G. G., Ghio, A. J., Kao, P. N., & Upadhyay, D. (2005). Lung surfactant gelation induced by epithelial cells exposed to air pollution or oxidative stress. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 33(2), 161-168.

Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus
Graham, K. L., Thibault, D. L., Steinman, J. B., Okeke, L., Kao, P. N., & Utz, P. J. (2005). Granzyme B is dispensable for immunologic tolerance to self in a murine model of systemic lupus erythematosus. ARTHRITIS AND RHEUMATISM, 52(6), 1684-1693.

NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3 '-untranslated region of MyoD and p21(WAF1/CIP1) mRNAs
Shi, L. F., Zhao, G. H., Qiu, D. M., Godfrey, W. R., Vogel, H., & Kao, P. N. (2005). NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3 '-untranslated region of MyoD and p21(WAF1/CIP1) mRNAs. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(19), 18981-18989.

NF45/ILF2 tissue expression, promoter analysis, and interleukin-2 transactivating function
Zhao, G. H., Shi, L. F., Qiu, D. M., Hu, H., & Kao, P. N. (2005). NF45/ILF2 tissue expression, promoter analysis, and interleukin-2 transactivating function. EXPERIMENTAL CELL RESEARCH, 305(2), 312-323.

Simvastatin treatment of pulmonary hypertension - An observational case series
Kao, P. N. (2005). Simvastatin treatment of pulmonary hypertension - An observational case series. CHEST, 127(4), 1446-1452.

Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats
Vaszar, L. T., Nishimura, T., Storey, J. D., Zhao, G. H., Qiu, D. M., & Kao, P. N. (2004). Longitudinal transcriptional analysis of developing neointimal vascular occlusion and pulmonary hypertension in rats. PHYSIOLOGICAL GENOMICS, 17(2), 150-156.

Members of the NF90/NFAR protein group are involved in the life cycle of a positive-strand RNA virus
Isken, O., Grassmann, C. W., Sarisky, R. T., Kann, M., Zhang, S., & Behrens, S. E. (2003). Members of the NF90/NFAR protein group are involved in the life cycle of a positive-strand RNA virus. EMBO JOURNAL, 22(21), 5655-5665.

Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells
Nishimura, T., Vaszar, L. T., Faul, J. L., Zhao, G. H., Berry, G. J., & Kao, P. N. (2003). Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells. CIRCULATION, 108(13), 1640-1645.

Selective regulation of gene expression by nuclear factor 110, a member of the NF90 family of double-stranded RNA-binding proteins
Reichman, T. W., Parrott, A. M., Fierro-Monti, I., Caron, D. J., Kao, P. N., & Mathews, M. B. (2003). Selective regulation of gene expression by nuclear factor 110, a member of the NF90 family of double-stranded RNA-binding proteins. JOURNAL OF MOLECULAR BIOLOGY, 332(1), 85-98.

Effect of a surgical aortocaval fistula on mono crotaline-induced pulmonary hypertension
Nishimura, T., Faul, J. L., Berry, G. J., Kao, P. N., & Pearl, R. G. (2003). Effect of a surgical aortocaval fistula on mono crotaline-induced pulmonary hypertension. CRITICAL CARE MEDICINE, 31(4), 1213-1218.

Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f.
Qiu, D., & Kao, P. N. (2003). Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f. Drugs in R&D, 4(1), 1-18.

Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats
Nishimura, T., Faul, J. L., Berry, G. J., Vaszar, L. T., Qiu, D. M., & Kao, P. N. (2002). Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 166(10), 1403-1408.

High prevalence of autoimmune thyroid disease in pulmonary arterial hypertension
Chu, J. W., Kao, P. N., Faul, J. L., & Doyle, R. L. (2002). High prevalence of autoimmune thyroid disease in pulmonary arterial hypertension. CHEST, 122(5), 1668-1673.

40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats
Nishimura, T., Faul, J. L., Berry, G. I., Veve, I., Pearl, R. G., & Kao, P. N. (2001). 40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 163(2), 498-502.

Triptolide attenuates pulmonary arterial hypertension and neointimal formation in rats
Faul, J. L., Nishimura, T., Berry, G. J., BENSON, G. V., Pearl, R. G., & Kao, P. N. (2000). Triptolide attenuates pulmonary arterial hypertension and neointimal formation in rats. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 162(6), 2252-2258.

Anti-inflammatory effects of triptolide in human bronchial epithelial cells
Zhao, G. H., Vaszar, L. T., Qiu, D. M., Shi, L. F., & Kao, P. N. (2000). Anti-inflammatory effects of triptolide in human bronchial epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 279(5), L958-L966.

Protein-arginine methyltransferase I, the predominant protein-arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3
Tang, J., Kao, P. N., & Herschman, H. R. (2000). Protein-arginine methyltransferase I, the predominant protein-arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3. JOURNAL OF BIOLOGICAL CHEMISTRY, 275(26), 19866-19876.

Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity
Satoh, M., Shaheen, V. M., Kao, P. N., Okano, T., Shaw, M., & Reeves, W. H. (1999). Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity. JOURNAL OF BIOLOGICAL CHEMISTRY, 274(49), 34598-34604.

Erythromycin inhibits transcriptional activation of NF-kappa B, but not NFAT, through calcineurin-independent signaling in T cells
Aoki, Y., & Kao, P. N. (1999). Erythromycin inhibits transcriptional activation of NF-kappa B, but not NFAT, through calcineurin-independent signaling in T cells. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 43(11), 2678-2684.

Tick-borne pulmonary disease - Update on diagnosis and management
Faul, J. L., Doyle, R. L., Kao, P. N., & Ruoss, S. J. (1999). Tick-borne pulmonary disease - Update on diagnosis and management. CHEST, 116(1), 222-230.

Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR
Langland, J. O., Kao, P. N., & Jacobs, B. L. (1999). Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR. BIOCHEMISTRY, 38(19), 6361-6368.

PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells
Lee, K. Y., Chang, W. T., Qiu, D. M., Kao, P. N., & Rosen, G. D. (1999). PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 274(19), 13451-13455.

Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappa B transcriptional activation
Qiu, D. M., Zhao, G. H., Aoki, Y., Shi, L. F., Uyei, A., & Kao, P. N. (1999). Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappa B transcriptional activation. JOURNAL OF BIOLOGICAL CHEMISTRY, 274(19), 13443-13450.

Mycobacterium avium-intracellulare pulmonary infection in HIV-negative patients without preexisting lung disease - Diagnostic and management limitations
Huang, J. H., Kao, P. N., Adi, V., & Ruoss, S. J. (1999). Mycobacterium avium-intracellulare pulmonary infection in HIV-negative patients without preexisting lung disease - Diagnostic and management limitations. CHEST, 115(4), 1033-1040.

Diaphragmatic paralysis due to Lyme disease
Faul, J. L., Ruoss, S., Doyle, R. L., & Kao, P. N. (1999). Diaphragmatic paralysis due to Lyme disease. EUROPEAN RESPIRATORY JOURNAL, 13(3), 700-702.

CsA-sensitive purine-box transcriptional regulator in bronchial epithelial cells contains NF45, NF90, and Ku
Aoki, Y., Zhao, G. H., Qiu, D. M., Shi, L. F., & Kao, P. N. (1998). CsA-sensitive purine-box transcriptional regulator in bronchial epithelial cells contains NF45, NF90, and Ku. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 275(6), L1164-L1172.

Leukotriene B-4 mediates histamine induction of NF-kappa B and IL-8 in human bronchial epithelial cells
Aoki, Y., Qiu, D. M., Zhao, G. H., & Kao, P. N. (1998). Leukotriene B-4 mediates histamine induction of NF-kappa B and IL-8 in human bronchial epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 274(6), L1030-L1039.

Analyses of the NRAMP1 and IFN-gamma R1 genes in women with Mycobacterium avium-intracellulare pulmonary disease
Huang, J. H., Oefner, P. J., Adi, V., Ratnam, K., Ruoss, S. J., & Kao, P. N. (1998). Analyses of the NRAMP1 and IFN-gamma R1 genes in women with Mycobacterium avium-intracellulare pulmonary disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 157(2), 377-381.

DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45
Ting, N. Sy., Kao, P. N., Chan, D. W., Lintott, L. G., & Lees-Miller, S. P. (1998). DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45. JOURNAL OF BIOLOGICAL CHEMISTRY, 273(4), 2136-2145.

Cyclosporin A-sensitive calcium signaling represses NF kappa B activation in human bronchial epithelial cells and enhances NF kappa B activation in Jurkat T-cells
Aoki, Y., & Kao, P. N. (1997). Cyclosporin A-sensitive calcium signaling represses NF kappa B activation in human bronchial epithelial cells and enhances NF kappa B activation in Jurkat T-cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 234(2), 424-431.

Human airway epithelial cells express interleukin-2 in vitro
Aoki, Y., Diu, D. M., Uyei, A., & Kao, P. N. (1997). Human airway epithelial cells express interleukin-2 in vitro. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 272(2), L276-L286.

PURIFICATION BY DNA AFFINITY-CHROMATOGRAPHY OF 2 POLYPEPTIDES THAT CONTACT THE NF-AT DNA-BINDING SITE IN THE INTERLEUKIN-2 PROMOTER
Corthesy, B., & Kao, P. N. (1994). PURIFICATION BY DNA AFFINITY-CHROMATOGRAPHY OF 2 POLYPEPTIDES THAT CONTACT THE NF-AT DNA-BINDING SITE IN THE INTERLEUKIN-2 PROMOTER. JOURNAL OF BIOLOGICAL CHEMISTRY, 269(32), 20682-20690.

CLONING AND EXPRESSION OF CYCLOSPORINE-A-SENSITIVE AND FK506-SENSITIVE NUCLEAR FACTOR OF ACTIVATED T-CELLS - NF45 AND NF90
Kao, P. N., Chen, L., Brock, G., Ng, J., Kenny, J., & Corthesy, B. (1994). CLONING AND EXPRESSION OF CYCLOSPORINE-A-SENSITIVE AND FK506-SENSITIVE NUCLEAR FACTOR OF ACTIVATED T-CELLS - NF45 AND NF90. JOURNAL OF BIOLOGICAL CHEMISTRY, 269(32), 20691-20699.

ACETYLCHOLINE-RECEPTOR BINDING-SITE CONTAINS A DISULFIDE CROSS-LINK BETWEEN ADJACENT HALF-CYSTINYL RESIDUES
Kao, P. N., & Karlin, A. (1986). ACETYLCHOLINE-RECEPTOR BINDING-SITE CONTAINS A DISULFIDE CROSS-LINK BETWEEN ADJACENT HALF-CYSTINYL RESIDUES. JOURNAL OF BIOLOGICAL CHEMISTRY, 261(18), 8085-8088.

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.
Kao, P. N., Dwork, A. J., KALDANY, R. R., SILVER, M. L., Wideman, J., & Karlin, A. (1984). Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site. journal of biological chemistry, 259(19), 11662-11665.

THE ACTIVE GUANIDINIUM GROUP OF SAXITOXIN AND NEOSAXITOXIN IDENTIFIED BY THE EFFECTS OF PH ON THEIR ACTIVITIES ON SQUID AXON
Kao, P. N., JAMESKRACKE, M. R., & Kao, C. Y. (1983). THE ACTIVE GUANIDINIUM GROUP OF SAXITOXIN AND NEOSAXITOXIN IDENTIFIED BY THE EFFECTS OF PH ON THEIR ACTIVITIES ON SQUID AXON. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 398(3), 199-203.