Anson Lowe, MD

Gastroenterologist, Pancreas specialist, General gastroenterologist

Associate Professor of Medicine (Gastroenterology and Hepatology)

Digestive Health Center

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-736-5555
Learn More About the Clinic Getting Here Make An Appointment

Digestive Health Center - Endoscopy Suite at Stanford

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-736-5555
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Digestive Health Center in Redwood City (Endoscopy Suite)

  • 450 Broadway Street
  • Redwood City, CA 94063
  • Phone: 650-736-5555
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Professional Education

Medical Education: Mt Sinai School of Medicine (1980) NY

Residency: Presbyterian Hospital (1983) NY

Board Certification: Gastroenterology, American Board of Internal Medicine (1987)

Fellowship: UCSF Medical Center (1989) CA

Fellowship: Columbia University School of Public Health (1984) NY

Board Certification: Internal Medicine, American Board of Internal Medicine (1983)

Internship: Presbyterian Hospital (1981) NY

MD, Mt. Sinai Sch. of Med., Medicine (1980)

BA, UC Berkeley, Physiology (1976)

Honors & Awards

American Gastroenterology Association Fellow, American Gastroenterology Association (2009)

Lester R. Tuchman Award for clinical excellence (graduating class award), Mount Sinai Hospital (1980)

AOA inductee, Alpha Omega Alpha Honor Medical Society (1979)

Division Teaching Award, Stanford University (2001, 2004, 2007, 2008, 2012)

Administrative Appointments

Associate Director, Stanford Digestive Disease Center, Stanford University (2001 - 2012)

Co-Director, Stanford Gastroenterology Training Program, Stanford University (2012 - Present)

Special Sections Editor, Gastroenterology (journal) (2011 - Present)

Associate Editor, The American Journal of Medicine (2000 - 2004)

Member, Stanford School of Medicine Awards Committee, Stanford University (2001 - Present)

Co-Course Director - Human Health & Disease, Stanford University (2004 - Present)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Detection of pancreatic ductal adenocarcinoma in mice by ultrasound imaging of thymocyte differentiation antigen 1.
Foygel, K., Wang, H., Machtaler, S., Lutz, A. M., Chen, R., & Willmann, J. K. (2013). Detection of pancreatic ductal adenocarcinoma in mice by ultrasound imaging of thymocyte differentiation antigen 1. Gastroenterology, 145(4), 885-894 e3.

Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine.
Park, W. G., Wu, M., Bowen, R., Zheng, M., Fitch, W. L., & Peltz, G. (2013). Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine. Gastrointestinal endoscopy, 78(2), 295-302 e2.

CITED2 is a novel direct effector of peroxisome proliferator-activated receptor gamma in suppressing hepatocellular carcinoma cell growth
Cheung, K.-F., Zhao, J., Hao, Y., Li, X., Lowe, A. W., & Yu, J. (2013). CITED2 is a novel direct effector of peroxisome proliferator-activated receptor gamma in suppressing hepatocellular carcinoma cell growth. CANCER, 119(6), 1217-1226.

Loss of Anterior Gradient 2 (Agr2) Expression Results in Hyperplasia and Defective Lineage Maturation in the Murine Stomach
Gupta, A., Wodziak, D., Tun, M., Bouley, D. M., & Lowe, A. W. (2013). Loss of Anterior Gradient 2 (Agr2) Expression Results in Hyperplasia and Defective Lineage Maturation in the Murine Stomach. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(6), 4321-4333.

Immunohistochemical panel for distinguishing esophageal adenocarcinoma from squamous cell carcinoma: a combination of p63, cytokeratin 5/6, MUC5AC, and anterior gradient homolog 2 allows optimal subtyping
DiMaio, M. A., Kwok, S., Montgomery, K. D., Lowe, A. W., & Pai, R. K. (2012). Immunohistochemical panel for distinguishing esophageal adenocarcinoma from squamous cell carcinoma: a combination of p63, cytokeratin 5/6, MUC5AC, and anterior gradient homolog 2 allows optimal subtyping. HUMAN PATHOLOGY, 43(11), 1799-1807.

PDX1 regulation of FABP1 and novel target genes in human intestinal epithelial Caco-2 cells
Chen, C., Fang, R., Chou, L.-C., Lowe, A. W., & Sibley, E. (2012). PDX1 regulation of FABP1 and novel target genes in human intestinal epithelial Caco-2 cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 423(1), 183-187.

Diagnostic accuracy of cyst fluid amphiregulin in pancreatic cysts
Tun, M. T., Pai, R. K., Kwok, S., Dong, A., Gupta, A., & Park, W. G. (2012). Diagnostic accuracy of cyst fluid amphiregulin in pancreatic cysts. BMC GASTROENTEROLOGY, 12.

AGR2 Gene Function Requires a Unique Endoplasmic Reticulum Localization Motif
Gupta, A., Dong, A., & Lowe, A. W. (2012). AGR2 Gene Function Requires a Unique Endoplasmic Reticulum Localization Motif. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(7), 4773-4782.

The Human Adenocarcinoma-associated Gene, AGR2, Induces Expression of Amphiregulin through Hippo Pathway Co-activator YAP1 Activation
Dong, A., Gupta, A., Pai, R. K., Tun, M., & Lowe, A. W. (2011). The Human Adenocarcinoma-associated Gene, AGR2, Induces Expression of Amphiregulin through Hippo Pathway Co-activator YAP1 Activation. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(20), 18301-18310.

Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response
Hase, K., Kawano, K., Nochi, T., Pontes, G. S., Fukuda, S., & Ohno, H. (2009). Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. NATURE, 462(7270), 226-U101.

The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli type 1 Fimbriae
Yu, S., & Lowe, A. W. (2009). The pancreatic zymogen granule membrane protein, GP2, binds Escherichia coli type 1 Fimbriae. BMC GASTROENTEROLOGY.

Painless Jaundice and Bilaterally Enlarged Sub-mandibular Glands in an Elderly Man
Park, W. G., Pai, R., Ro, K., & Lowe, A. W. (2009). Painless Jaundice and Bilaterally Enlarged Sub-mandibular Glands in an Elderly Man. DIGESTIVE DISEASES AND SCIENCES, 54(3), 488-490.

Endoscopic evaluation of esophago-gastro-jejunostomy in rat model of Barrett's esophagus
Lu, S., Lowe, A. W., Triadafilopoulos, G., Hsiung, P.-L., Hao, Y., & Wang, T. D. (2009). Endoscopic evaluation of esophago-gastro-jejunostomy in rat model of Barrett's esophagus. DISEASES OF THE ESOPHAGUS, 22(4), 323-330.

Comprehensive gene expression profiling of Peyer's patch M cells, villous M-like cells, and intestinal epithelial cells
Terahara, K., Yoshida, M., Igarashi, O., Nochi, T., Pontes, G. S., & Kiyono, H. (2008). Comprehensive gene expression profiling of Peyer's patch M cells, villous M-like cells, and intestinal epithelial cells. JOURNAL OF IMMUNOLOGY, 180(12), 7840-7846.

Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy
Hsiung, P.- lin, Hardy, J., Friedland, S., Soetikno, R., Du, C. B., & Wang, T. D. (2008). Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy. NATURE MEDICINE, 14(4), 454-458.

The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without ha-ras co-transfection
Einav, S., Sklan, E. H., Moon, H. M., Gehrig, E., Liu, P., & Glenn, J. S. (2008). The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without ha-ras co-transfection. HEPATOLOGY, 47(3), 827-835.

The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation
Wang, Z., Hao, Y., & Lowe, A. W. (2008). The adenocarcinoma-associated antigen, AGR2, promotes tumor growth, cell migration, and cellular transformation. CANCER RESEARCH, 68(2), 492-497.

Gene expression profiles in gallbladder cancer: The close genetic similarity seen for early and advanced gallbladder cancers may explain the poor prognosis
Kim, J. hyang, Kim, H. N., Lee, K. T., Lee, J. K., Choi, S.-H., & Lowe, A. W. (2008). Gene expression profiles in gallbladder cancer: The close genetic similarity seen for early and advanced gallbladder cancers may explain the poor prognosis. TUMOR BIOLOGY, 29(1), 41-49.

Physiological and molecular analysis of acid loading mechanisms in squamous and columnar-lined esophagus
Lao-Sirieix, P., Corovic, A., Jankowski, J., Lowe, A., Triadafilopoulos, G., & Fitzgerald, R. C. (2008). Physiological and molecular analysis of acid loading mechanisms in squamous and columnar-lined esophagus. DISEASES OF THE ESOPHAGUS, 21(6), 529-538.

Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7
Boonstra, J. J., van der Velden, A. W., Beerens, E. Cw., van Marion, R., Morita-Fujimura, Y., & Dinjens, W. Nm. (2007). Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7. CANCER RESEARCH, 67(17), 7996-8001.

Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure
Hao, Y., Sood, S., Triadafilopoulos, G., Kim, J. H., Wang, Z., & Lowe, A. W. (2007). Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure. BMC GASTROENTEROLOGY, 7.

Gene expression profiling in lymph node-positive and lymph node-negative pancreatic cancer
Kim, H. N., Choi, D. W., Lee, K. T., Lee, J. K., Heo, J. S., & Lowe, A. W. (2007). Gene expression profiling in lymph node-positive and lymph node-negative pancreatic cancer. PANCREAS, 34(3), 325-334.

Gene Expression Patterns in Pancreatic Tumors, Cells and Tissues
Lowe, A. W., Olsen, M., Hao, Y., Lee, S. P., Lee, K. T., & Brown, P. O. (2007). Gene Expression Patterns in Pancreatic Tumors, Cells and Tissues. PLOS ONE, 2(3).

The pancreatic stellate cell: a star on the rise in pancreatic diseases
Omary, M. B., Lugea, A., Lowe, A. W., & Pandol, S. J. (2007). The pancreatic stellate cell: a star on the rise in pancreatic diseases. JOURNAL OF CLINICAL INVESTIGATION, 117(1), 50-59.

Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma
Hao, Y., Triadafilopoulos, G., Sahbaie, P., Young, H. S., Omary, M. B., & Lowe, A. W. (2006). Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma. GASTROENTEROLOGY, 131(3), 925-933.

The genome is now accessible to the endoscopist
Lowe, A. W. (2006). The genome is now accessible to the endoscopist. GASTROINTESTINAL ENDOSCOPY, 64(1), 27-28.

Absence of the major zymogen granule membrane protein, GP2, does not affect pancreatic morphology or secretion
Yu, S., Michie, S. A., & Lowe, A. W. (2004). Absence of the major zymogen granule membrane protein, GP2, does not affect pancreatic morphology or secretion. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(48), 50274-50279.

Effects of GP2 expression on secretion and endocytosis in pancreatic AR4-2J cells
Yu, S., Hao, Y., & Lowe, A. W. (2004). Effects of GP2 expression on secretion and endocytosis in pancreatic AR4-2J cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 322(1), 320-325.

Determination of plasma glycoprotein 2 levels in patients with pancreatic disease
Hao, Y., Wang, J., Feng, N. G., & Lowe, A. W. (2004). Determination of plasma glycoprotein 2 levels in patients with pancreatic disease. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 128(6), 668-674.

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
Iacobuzio-Donahue, C. A., Maitra, A., Olsen, M., Lowe, A. W., van Heek, N. T., & Goggins, M. (2003). Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. AMERICAN JOURNAL OF PATHOLOGY, 162(4), 1151-1162.

Hyposmotic stress induces cell growth arrest via proteasome activation and cyclin/cyclin-dependent kinase degradation
Tao, G. Z., Rott, L. S., Lowe, A. W., & Omary, M. B. (2002). Hyposmotic stress induces cell growth arrest via proteasome activation and cyclin/cyclin-dependent kinase degradation. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(22), 19295-19303.

Processing of the major pancreatic zymogen granule membrane protein, GP2
Fritz, B. A., Poppel, C. S., Fei, M. W., & Lowe, A. W. (2002). Processing of the major pancreatic zymogen granule membrane protein, GP2. PANCREAS, 24(4), 336-343.

Effects of keratin filament disruption on exocrine pancreas-stimulated secretion and susceptibility to injury
Toivola, D. M., Ku, N. O., Ghori, N., Lowe, A. W., Michie, S. A., & Omary, M. B. (2000). Effects of keratin filament disruption on exocrine pancreas-stimulated secretion and susceptibility to injury. EXPERIMENTAL CELL RESEARCH, 255(2), 156-170.

Characterization of an alternatively spliced isoform of rat vesicle associated membrane protein-2 (VAMP-2)
Mandic, R., & Lowe, A. W. (1999). Characterization of an alternatively spliced isoform of rat vesicle associated membrane protein-2 (VAMP-2). FEBS LETTERS, 451(2), 209-213.

Tissue-specific alternative RNA splicing of rat vesicle-associated membrane protein-1 (VAMP-1)
Mandic, R., Trimble, W. S., & Lowe, A. W. (1997). Tissue-specific alternative RNA splicing of rat vesicle-associated membrane protein-1 (VAMP-1). GENE, 199(1-2), 173-179.

Sequence of the cDNA encoding human GP-2, the major membrane protein in the secretory granule of the exocrine pancreas
Wong, S. Me., & Lowe, A. W. (1996). Sequence of the cDNA encoding human GP-2, the major membrane protein in the secretory granule of the exocrine pancreas. GENE, 171(2), 311-312.

Polarized GP2 secretion in MDCK cells via GPI targeting and apical membrane-restricted proteolysis
Fritz, B. A., & Lowe, A. W. (1996). Polarized GP2 secretion in MDCK cells via GPI targeting and apical membrane-restricted proteolysis. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 270(1), G176-G183.

HIERARCHY OF MECHANISMS INVOLVED IN GENERATING NA/K-ATPASE POLARITY IN MDCK EPITHELIAL-CELLS
Mays, R. W., Siemers, K. A., Fritz, B. A., Lowe, A. W., VANMEER, G., & NELSON, W. J. (1995). HIERARCHY OF MECHANISMS INVOLVED IN GENERATING NA/K-ATPASE POLARITY IN MDCK EPITHELIAL-CELLS. JOURNAL OF CELL BIOLOGY, 130(5), 1105-1115.

THE LEVEL OF THE ZYMOGEN GRANULE PROTEIN GP2 IS ELEVATED IN A RAT MODEL FOR ACUTE-PANCREATITIS
Lowe, A. W., Luthen, R. E., Wong, S. Me., & Grendell, J. H. (1994). THE LEVEL OF THE ZYMOGEN GRANULE PROTEIN GP2 IS ELEVATED IN A RAT MODEL FOR ACUTE-PANCREATITIS. GASTROENTEROLOGY, 107(6), 1819-1827.

APICAL PLASMA-MEMBRANE PROTEINS ARE NOT OBLIGATORILY STORED IN SECRETORY GRANULES IN EXOCRINE CELLS
Colomer, V., Rindler, M. J., & Lowe, A. W. (1994). APICAL PLASMA-MEMBRANE PROTEINS ARE NOT OBLIGATORILY STORED IN SECRETORY GRANULES IN EXOCRINE CELLS. JOURNAL OF CELL SCIENCE, 107, 2271-2277.

IDENTIFICATION OF A VESICLE-ASSOCIATED MEMBRANE-PROTEIN (VAMP)-LIKE MEMBRANE-PROTEIN IN ZYMOGEN GRANULES OF THE RAT EXOCRINE PANCREAS
Braun, J. Ea., Fritz, B. A., Wong, S. Me., & Lowe, A. W. (1994). IDENTIFICATION OF A VESICLE-ASSOCIATED MEMBRANE-PROTEIN (VAMP)-LIKE MEMBRANE-PROTEIN IN ZYMOGEN GRANULES OF THE RAT EXOCRINE PANCREAS. JOURNAL OF BIOLOGICAL CHEMISTRY, 269(7), 5328-5335.

ANTISENSE OLIGODEOXYNUCLEOTIDES TO THE CYSTIC-FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR INHIBIT CAMP-ACTIVATED BUT NOT CALCIUM-ACTIVATED CHLORIDE CURRENTS
Wagner, J. A., McDonald, T. V., NGHIEM, P. T., Lowe, A. W., Schulman, H., & Gardner, P. (1992). ANTISENSE OLIGODEOXYNUCLEOTIDES TO THE CYSTIC-FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR INHIBIT CAMP-ACTIVATED BUT NOT CALCIUM-ACTIVATED CHLORIDE CURRENTS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 89(15), 6785-6789.