David B. Lewis

Professional Education

Board Certification: Pediatrics, American Board of Pediatrics (1986)

Medical Education: UCSF Medical Center (1981) CA

Fellowship: Children's Hospital and Regional Medical Center (1988) WA

Residency: UCSF Medical Center (1984) CA

Board Certification: Pediatric Infectious Disease, American Board of Pediatrics (1994)

Internship: Children's Hospital and Regional Medical Center (1982) WA

M.D., Univ.Calif at San Francisco, Medicine (1981)

B.S., Yale University, Biology (1976)

Honors & Awards

Henry J. Kaiser Award for Excellence in Preclinical Teaching (Immunology), Kaiser Foundation (2005)

Henry J. Kaiser Award for Excellence in Preclinical Teaching (Immunology), Kaiser Foundation (2001)

Administrative Appointments

Chief, Stanford Department of Pediatrics, Division of Immunology and Allergy, 2008

Professor, Stanford University, Department of Pediatrics, 2005

Director of the Jeffrey Modell Primary Immunodeficiency Center at Stanford, Supported by the Jeffrey Modell Foundation and the Lucile Packard Fund of Children's Health, 2002

Associate Professor, Stanford University, Department of Pediatrics, 1997

Acting Associate Professor, Stanford University, Department of Pediatrics, 1997

Human Neonatal Naive CD4(+) T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a
Palin, A. C., Ramachandran, V., Acharya, S., & Lewis, D. B. (2013). Human Neonatal Naive CD4(+) T Cells Have Enhanced Activation-Dependent Signaling Regulated by the MicroRNA miR-181a. JOURNAL OF IMMUNOLOGY, 190(6), 2682-2691.

Genotype, phenotype, and outcomes of nine patients with T-B plus NK plus SCID
Yu, G. P., Nadeau, K. C., Berk, D. R., de Saint Basile, G., Lambert, N., & Cowan, M. J. (2011). Genotype, phenotype, and outcomes of nine patients with T-B plus NK plus SCID. PEDIATRIC TRANSPLANTATION, 15(7), 733-741.

Protein tyrosine kinase 7: a novel surface marker for human recent thymic emigrants with potential clinical utility
Lewis, D. B., Haines, C., & Ross, D. (2011). Protein tyrosine kinase 7: a novel surface marker for human recent thymic emigrants with potential clinical utility. JOURNAL OF PERINATOLOGY, 31, S72-S81.

CROSS-REACTIVE NEUTRALIZING ANTIBODY AGAINST PANDEMIC 2009 H1N1 INFLUENZA A VIRUS IN INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS
Hong, D. K., Tremoulet, A. H., Burns, J. C., & Lewis, D. B. (2011). CROSS-REACTIVE NEUTRALIZING ANTIBODY AGAINST PANDEMIC 2009 H1N1 INFLUENZA A VIRUS IN INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 30(1), 67-69.

Cationic Lipid/DNA Complex-Adjuvanted Influenza A Virus Vaccination Induces Robust Cross-Protective Immunity
Hong, D. K., Chang, S., Botham, C. M., Giffon, T. D., Fairman, J., & Lewis, D. B. (2010). Cationic Lipid/DNA Complex-Adjuvanted Influenza A Virus Vaccination Induces Robust Cross-Protective Immunity. JOURNAL OF VIROLOGY, 84(24), 12691-12702.

Revisiting Human IL-12R beta 1 Deficiency A Survey of 141 Patients From 30 Countries
de Beaucoudrey, L., Samarina, A., Bustamante, J., Cobat, A., Boisson-Dupuis, S., & Casanova, J.-L. (2010). Revisiting Human IL-12R beta 1 Deficiency A Survey of 141 Patients From 30 Countries. MEDICINE, 89(6), 381-402.

Alternate Mechanisms of Initial Pattern Recognition Drive Differential Immune Responses to Related Poxviruses
O'Gorman, W. E., Sampath, P., Simonds, E. F., Sikorski, R., O'Malley, M., & Nolan, G. P. (2010). Alternate Mechanisms of Initial Pattern Recognition Drive Differential Immune Responses to Related Poxviruses. CELL HOST & MICROBE, 8(2), 174-185.

Adult-onset presentations of genetic immunodeficiencies: genes can throw slow curves
Nelson, K. S., & Lewis, D. B. (2010). Adult-onset presentations of genetic immunodeficiencies: genes can throw slow curves. CURRENT OPINION IN INFECTIOUS DISEASES, 23(4), 359-364.

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40(phox) and selective defects in neutrophil NADPH oxidase activity
Matute, J. D., Arias, A. A., Wright, N. Am., Wrobel, I., Waterhouse, C. Cm., & Dinauer, M. C. (2009). A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40(phox) and selective defects in neutrophil NADPH oxidase activity. BLOOD, 114(15), 3309-3315.

Efficient Induction and Expansion of Human Alloantigen-Specific CD8 Regulatory T Cells from Naive Precursors by CD40-Activated B Cells
Zheng, J., Liu, Y., Qin, G., Chan, P.-L., Mao, H., & Tu, W. (2009). Efficient Induction and Expansion of Human Alloantigen-Specific CD8 Regulatory T Cells from Naive Precursors by CD40-Activated B Cells. JOURNAL OF IMMUNOLOGY, 183(6), 3742-3750.

Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone (R)) increases antibody response, cellular immunity, and antigenically drifted protection
Lay, M., Callejo, B., Chang, S., Hong, D. K., Lewis, D. B., & Fairman, J. (2009). Cationic lipid/DNA complexes (JVRS-100) combined with influenza vaccine (Fluzone (R)) increases antibody response, cellular immunity, and antigenically drifted protection. VACCINE, 27(29), 3811-3820.

Human CD4(+) T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
Haines, C. J., Giffon, T. D., Lu, L.-S., Lu, X., Tessier-Lavigne, M., & Lewis, D. B. (2009). Human CD4(+) T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function. JOURNAL OF EXPERIMENTAL MEDICINE, 206(2), 275-285.

Efficient generation of human alloantigen-specific CD4(+) regulatory T cells from naive precursors by CD40-activated B cells
Tu, W., Lau, Y.-L., Zheng, J., Liu, Y., Chan, P.-L., & Lewis, D. B. (2008). Efficient generation of human alloantigen-specific CD4(+) regulatory T cells from naive precursors by CD40-activated B cells. BLOOD, 112(6), 2554-2562.

Focus on FOCIS: The continuing diagnostic challenge of autosomal recessive chronic granulomatous disease
Yu, G., Hong, D. K., Dionis, K. Y., Rae, J., Heyworth, P. G., & Lewis, D. B. (2008). Focus on FOCIS: The continuing diagnostic challenge of autosomal recessive chronic granulomatous disease. CLINICAL IMMUNOLOGY, 128(2), 117-126.

Maternal T-cell engraftment associated with severe hemophagocytosis of the bone marrow in untreated X-linked severe combined immunodeficiency
Dvorak, C. C., Sandford, A., Fong, A., Cowan, M. J., George, T. L., & Lewis, D. B. (2008). Maternal T-cell engraftment associated with severe hemophagocytosis of the bone marrow in untreated X-linked severe combined immunodeficiency. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 30(5), 396-400.

Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: Modulation by sirolimus
Potena, L., Fearon, W. F., Sydow, K., Holweg, C., Luikart, H., & Cooke, J. P. (2008). Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: Modulation by sirolimus. TRANSPLANTATION, 85(6), 827-833.

A novel mutation associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Bhui, R. D., Lewis, D. B., & Nadeau, K. C. (2008). A novel mutation associated with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 100(2), 169-169.

Influenza A virus elevates active cathepsin B in primary murine DC
Burster, T., Giffon, T., Dahl, M. E., Bjorck, P., Bogy, M., & Mellins, E. D. (2007). Influenza A virus elevates active cathepsin B in primary murine DC. INTERNATIONAL IMMUNOLOGY, 19(5), 645-655.

[Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome].
Potena, L., Ferrara, R., Mocarski, E. S., Lewis, D. B., Cooke, J. P., & Branzi, A. (2007). [Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome]. Giornale italiano di cardiologia (2006), 8(2), 73-82.

Humoral and cellular immune responses in children given annual immunization with trivalent inactivated influenza vaccine
Zeman, A. M., Holmes, T. H., Stamatis, S., Tu, W., He, X.-S., & Dekker, C. L. (2007). Humoral and cellular immune responses in children given annual immunization with trivalent inactivated influenza vaccine. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 26(2), 107-115.

Cellular immune responses in children and adults receiving inactivated or live attenuated influenza vaccines
He, X.-S., Holmes, T. H., Zhang, C., Mahmood, K., Kemble, G. W., & Arvin, A. M. (2006). Cellular immune responses in children and adults receiving inactivated or live attenuated influenza vaccines. JOURNAL OF VIROLOGY, 80(23), 11756-11766.

T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease
Tu, W., Potena, L., Stepick-Biek, P., Liu, L., Dionis, K. Y., & Lewis, D. B. (2006). T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease. CIRCULATION, 114(15), 1608-1615.

Cutting edge: Decreased accumulation and regulatory function of CD4(+)CD25(high) T cells in human STAT 5b deficiency
Cohen, A. C., Nadeau, K. C., Tu, W., Hwa, V., Dionis, K., & Lewis, D. B. (2006). Cutting edge: Decreased accumulation and regulatory function of CD4(+)CD25(high) T cells in human STAT 5b deficiency. JOURNAL OF IMMUNOLOGY, 177(5), 2770-2774.

Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection
Potena, L., Holweg, C. Tj., Chin, C., Luikart, H., Weisshaar, D., & Valantine, H. A. (2006). Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. TRANSPLANTATION, 82(3), 398-405.

Newborn immunology: relevance to the clinician.
Lewis, D. B., Gern, J. E., Hill, H. R., Friedlander, S. L., La Pine, T. R., & Stiehm, E. R. (2006). Newborn immunology: relevance to the clinician. Current problems in pediatric and adolescent health care, 36(5), 189-204.

Impaired allogeneic activation and T-helper differentiation of human cord blood naive CD4 T cells
Chen, L., Cohen, A. C., & Lewis, D. B. (2006). Impaired allogeneic activation and T-helper differentiation of human cord blood naive CD4 T cells. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 12(2), 160-171.

Chemotactic responses of IL-4-, IL-10-, and IFN-gamma-producing CD4(+) T cells depend on tissue origin and microbial stimulus
Debes, G. F., Dahl, M. E., Mahiny, A. J., Bonhagen, K., Campbell, D. J., & Hamann, A. (2006). Chemotactic responses of IL-4-, IL-10-, and IFN-gamma-producing CD4(+) T cells depend on tissue origin and microbial stimulus. JOURNAL OF IMMUNOLOGY, 176(1), 557-566.

Avian flu to human influenza
Lewis, D. B. (2006). Avian flu to human influenza. ANNUAL REVIEW OF MEDICINE, 57, 139-154.

Transient deficiencies of T-cell-mediated immunity in the neonate
Randolph, D. A., & Lewis, D. B. (2006). Transient deficiencies of T-cell-mediated immunity in the neonate. HOT TOPICS IN INFECTION AND IMMUNITY IN CHILDREN III, 582, 55-69.

Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
Zhou, B. H., Comeau, M. R., De Smedt, T., Liggitt, H. D., Dahl, M. E., & Ziegler, S. F. (2005). Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. NATURE IMMUNOLOGY, 6(10), 1047-1053.

Antiviral CD8 T cells in the control of primary human cytomegalovirus infection in early childhood
Chen, S. F., Tu, W. W., Sharp, M. A., Tongson, E. C., He, X. S., & Arvin, A. M. (2004). Antiviral CD8 T cells in the control of primary human cytomegalovirus infection in early childhood. JOURNAL OF INFECTIOUS DISEASES, 189(9), 1619-1627.

Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells
Dahl, M. E., Dabbagh, K., Liggitt, D., Kim, S., & Lewis, D. B. (2004). Viral-induced T helper type 1 responses enhance allergic disease by effects on lung dendritic cells. NATURE IMMUNOLOGY, 5(3), 337-343.

Persistent and selective deficiency of CD4(+) T cell immunity to cytomegalovirus in immunocompetent young children
Tu, W. W., Chen, S., Sharp, M., Dekker, C., Manganello, A. M., & Lewis, D. B. (2004). Persistent and selective deficiency of CD4(+) T cell immunity to cytomegalovirus in immunocompetent young children. JOURNAL OF IMMUNOLOGY, 172(5), 3260-3267.

Decreased CD154 expression by neonatal CD4(+) T cells is due to limitations in both proximal and distal events of T cell activation
JULLIEN, P., Cron, R. Q., Dabbagh, K., Cleary, A., Chen, L., & Lewis, D. B. (2003). Decreased CD154 expression by neonatal CD4(+) T cells is due to limitations in both proximal and distal events of T cell activation. INTERNATIONAL IMMUNOLOGY, 15(12), 1461-1472.

Toll-like receptors and T-helper-1/T-helper-2 responses
Dabbagh, K., & Lewis, D. B. (2003). Toll-like receptors and T-helper-1/T-helper-2 responses. CURRENT OPINION IN INFECTIOUS DISEASES, 16(3), 199-204.

Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency
Cleary, A. M., Tu, W. W., Enright, A., Giffon, T., Dewaal-Malefyt, R., & Lewis, D. B. (2003). Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency. JOURNAL OF IMMUNOLOGY, 170(1), 597-603.

Allergy immunotherapy and inhibition of Th2 immune responses: a sufficient strategy?
Lewis, D. B. (2002). Allergy immunotherapy and inhibition of Th2 immune responses: a sufficient strategy?. CURRENT OPINION IN IMMUNOLOGY, 14(5), 644-651.

Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors
Dunn, H. S., Haney, D. J., Ghanekar, S. A., Stepick-Biek, P., Lewis, D. B., & Maecker, H. T. (2002). Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors. JOURNAL OF INFECTIOUS DISEASES, 186(1), 15-22.

Simple febrile seizures - Do polymorphisms of the interleukin 1 gene cluster simplify our understanding?
Lewis, D. B. (2002). Simple febrile seizures - Do polymorphisms of the interleukin 1 gene cluster simplify our understanding?. ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 156(6), 529-530.

Toll-like receptor 4 is required for optimal development of Th2 immune responses: Role of dendritic cells
Dabbagh, K., Dahl, M. E., Stepick-Biek, P., & Lewis, D. B. (2002). Toll-like receptor 4 is required for optimal development of Th2 immune responses: Role of dendritic cells. JOURNAL OF IMMUNOLOGY, 168(9), 4524-4530.

A T cell-specific enhancer of the human CD40 ligand gene
Schubert, L. A., Cron, R. Q., Cleary, A. M., Brunner, M., Song, A., & Lewis, D. B. (2002). A T cell-specific enhancer of the human CD40 ligand gene. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(9), 7386-7395.

Group A streptococcal meningitis: Report of a case and review of literature since 1976
Shetty, A. K., Frankel, L. R., Maldonado, Y., Falco, D. A., & Lewis, D. B. (2001). Group A streptococcal meningitis: Report of a case and review of literature since 1976. PEDIATRIC EMERGENCY CARE, 17(6), 430-434.

Octamer proteins inhibit IL-4 gene transcription in normal human CD4 T cells
Cron, R. Q., Zhou, B., Brunvand, M. W., & Lewis, D. B. (2001). Octamer proteins inhibit IL-4 gene transcription in normal human CD4 T cells. GENES AND IMMUNITY, 2(8), 464-468.

Respiratory infection with influenza A virus interferes with the induction of tolerance to aeroallergens
Tsitoura, D. C., Kim, S., Dabbagh, K., Berry, G., Lewis, D. B., & Umetsu, D. T. (2000). Respiratory infection with influenza A virus interferes with the induction of tolerance to aeroallergens. JOURNAL OF IMMUNOLOGY, 165(6), 3484-3491.

Local blockade of allergic airway hyperreactivity and inflammation by the poxvirus-derived pan-CC-chemokine inhibitor vCCI
Dabbagh, K., Xiao, Y., Smith, C., Stepick-Biek, P., Kim, S. G., & Lewis, D. B. (2000). Local blockade of allergic airway hyperreactivity and inflammation by the poxvirus-derived pan-CC-chemokine inhibitor vCCI. JOURNAL OF IMMUNOLOGY, 165(6), 3418-3422.

An immunosuppressive and anti-inflammatory HLA class I-derived peptide binds vascular cell adhesion molecule-1
Ling, X. F., Tamaki, T., Xiao, Y., Kamangar, S., CLAYBERGER, C., & KRENSKY, A. M. (2000). An immunosuppressive and anti-inflammatory HLA class I-derived peptide binds vascular cell adhesion molecule-1. TRANSPLANTATION, 70(4), 662-667.

NFAT1 enhances HIV-1 gene expression in primary human CD4 T cells
Cron, R. Q., Bartz, S. R., Clausell, A., Bort, S. J., Klebanoff, S. J., & Lewis, D. B. (2000). NFAT1 enhances HIV-1 gene expression in primary human CD4 T cells. CLINICAL IMMUNOLOGY, 94(3), 179-191.

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., & Staudt, L. M. (2000). Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. NATURE, 403(6769), 503-511.

Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease
Zeng, D. F., Lewis, D., Dejbakhsh-Jones, S., Lan, F. S., Garcia-Ojeda, M., & Strober, S. (1999). Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease. JOURNAL OF EXPERIMENTAL MEDICINE, 189(7), 1073-1081.

T cell priming enhances IL-4 gene expression by increasing nuclear factor of activated T cells
Cron, R. Q., Bort, S. J., Wang, Y. X., Brunvand, M. W., & Lewis, D. B. (1999). T cell priming enhances IL-4 gene expression by increasing nuclear factor of activated T cells. JOURNAL OF IMMUNOLOGY, 162(2), 860-870.

Consistent transient transfection of DNA into non-transformed human and murine T-lymphocytes
Cron, R. Q., Schubert, L. A., Lewis, D. B., & HUGHES, C. Cw. (1997). Consistent transient transfection of DNA into non-transformed human and murine T-lymphocytes. JOURNAL OF IMMUNOLOGICAL METHODS, 205(2), 145-150.

Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response
Zhang, Y., Lamm, W. Je., Albert, R. K., Chi, E. Y., Henderson, W. R., & Lewis, D. B. (1997). Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 155(2), 661-669.

The importance of leukotrienes in airway inflammation in a mouse model of asthma
Henderson, W. R., Lewis, D. B., Albert, R. K., Zhang, Y., Lamm, W. Je., & Chi, E. Y. (1996). The importance of leukotrienes in airway inflammation in a mouse model of asthma. JOURNAL OF EXPERIMENTAL MEDICINE, 184(4), 1483-1494.

beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses
Zhang, Y., Rogers, K. H., & Lewis, D. B. (1996). beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses. JOURNAL OF EXPERIMENTAL MEDICINE, 184(4), 1507-1512.

Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31
Dolganov, G., Bort, S., LOVETT, M., Burr, J., Schubert, L., & Lewis, D. B. (1996). Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31. BLOOD, 87(8), 3316-3326.

THE HUMAN GP39 PROMOTER - 2 DISTINCT NUCLEAR FACTORS OF ACTIVATED T-CELL PROTEIN-BINDING ELEMENTS CONTRIBUTE INDEPENDENTLY TO TRANSCRIPTIONAL ACTIVATION
Schubert, L. A., King, G., Cron, R. Q., Lewis, D. B., Aruffo, A., & Hollenbaugh, D. (1995). THE HUMAN GP39 PROMOTER - 2 DISTINCT NUCLEAR FACTORS OF ACTIVATED T-CELL PROTEIN-BINDING ELEMENTS CONTRIBUTE INDEPENDENTLY TO TRANSCRIPTIONAL ACTIVATION. JOURNAL OF BIOLOGICAL CHEMISTRY, 270(50), 29624-29627.

HYPOMETHYLATION OF THE INTERFERON-GAMMA GENE CORRELATES WITH ITS EXPRESSION BY PRIMARY T-LINEAGE CELLS
Melvin, A. J., MCGURN, M. E., Bort, S. J., Gibson, C., & Lewis, D. B. (1995). HYPOMETHYLATION OF THE INTERFERON-GAMMA GENE CORRELATES WITH ITS EXPRESSION BY PRIMARY T-LINEAGE CELLS. EUROPEAN JOURNAL OF IMMUNOLOGY, 25(2), 426-430.

DIMINISHED EXPRESSION OF CD40 LIGAND BY ACTIVATED NEONATAL T-CELLS
Nonoyama, S., Penix, L. A., Edwards, C. P., Lewis, D. B., Ito, S., & Ochs, H. D. (1995). DIMINISHED EXPRESSION OF CD40 LIGAND BY ACTIVATED NEONATAL T-CELLS. JOURNAL OF CLINICAL INVESTIGATION, 95(1), 66-75.

OSTEOPOROSIS INDUCED IN MICE BY OVERPRODUCTION OF INTERLEUKIN-4
Lewis, D. B., Liggitt, H. D., Effmann, E. L., Motley, S. T., Teitelbaum, S. L., & Perlmutter, R. M. (1993). OSTEOPOROSIS INDUCED IN MICE BY OVERPRODUCTION OF INTERLEUKIN-4. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 90(24), 11618-11622.

LYMPHOKINE REGULATION AND THE ROLE OF ABNORMAL REGULATION IN IMMUNODEFICIENCY
Wilson, C. B., Penix, L., Melvin, A., & Lewis, D. B. (1993). LYMPHOKINE REGULATION AND THE ROLE OF ABNORMAL REGULATION IN IMMUNODEFICIENCY. CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 67(3), S25-S32.

ONTOGENY OF LYMPHOCYTE-T FUNCTION IN THE NEONATE
Wilson, C. B., Penix, L., Weaver, W. M., Melvin, A., & Lewis, D. B. (1992). ONTOGENY OF LYMPHOCYTE-T FUNCTION IN THE NEONATE. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 28(3-4), 132-135.

HAWKINSINURIA IN 2 FAMILIES
Borden, M., Holm, J., Leslie, J., Sweetman, L., Nyhan, W. L., & Scott, C. R. (1992). HAWKINSINURIA IN 2 FAMILIES. AMERICAN JOURNAL OF MEDICAL GENETICS, 44(1), 52-56.

CLINICAL AND MICROBIOLOGIC CHARACTERISTICS OF CUTANEOUS INFECTION WITH YERSINIA-ENTEROCOLITICA
Krogstad, P., Mendelman, P. M., MILLER, V. L., Clausen, C., Abbott, S., & Lewis, D. B. (1992). CLINICAL AND MICROBIOLOGIC CHARACTERISTICS OF CUTANEOUS INFECTION WITH YERSINIA-ENTEROCOLITICA. JOURNAL OF INFECTIOUS DISEASES, 165(4), 740-743.

DECREASED GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR PRODUCTION BY HUMAN NEONATAL BLOOD MONONUCLEAR-CELLS AND T-CELLS
English, B. K., Hammond, W. P., Lewis, D. B., Brown, C. B., & Wilson, C. B. (1992). DECREASED GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR PRODUCTION BY HUMAN NEONATAL BLOOD MONONUCLEAR-CELLS AND T-CELLS. PEDIATRIC RESEARCH, 31(3), 211-216.

DEVELOPMENTAL REGULATION OF LCK GENE-EXPRESSION IN LYMPHOCYTES-T
Wildin, R. S., Garvin, A. M., Pawar, S., Lewis, D. B., Abraham, K. M., & Perlmutter, R. M. (1991). DEVELOPMENTAL REGULATION OF LCK GENE-EXPRESSION IN LYMPHOCYTES-T. JOURNAL OF EXPERIMENTAL MEDICINE, 173(2), 383-393.

INTERLEUKIN-4 EXPRESSED INSITU SELECTIVELY ALTERS THYMOCYTE DEVELOPMENT
Lewis, D. B., Yu, C. C., Forbush, K. A., Carpenter, J., Sato, T. A., & Perlmutter, R. M. (1991). INTERLEUKIN-4 EXPRESSED INSITU SELECTIVELY ALTERS THYMOCYTE DEVELOPMENT. JOURNAL OF EXPERIMENTAL MEDICINE, 173(1), 89-100.

T cell development in the fetus and neonate.
Wilson, C. B., Lewis, D. B., & English, B. K. (1991). T cell development in the fetus and neonate. Advances in experimental medicine and biology, 310, 17-27.

CELLULAR AND MOLECULAR MECHANISMS FOR REDUCED INTERLEUKIN-4 AND INTERFERON-GAMMA PRODUCTION BY NEONATAL T-CELLS
Lewis, D. B., Yu, C. C., Meyer, J., English, B. K., Kahn, S. J., & Wilson, C. B. (1991). CELLULAR AND MOLECULAR MECHANISMS FOR REDUCED INTERLEUKIN-4 AND INTERFERON-GAMMA PRODUCTION BY NEONATAL T-CELLS. JOURNAL OF CLINICAL INVESTIGATION, 87(1), 194-202.

GAMMA-INTERFERON - AN IMMUNOREGULATORY LYMPHOKINE WITH IMMUNOTHERAPEUTIC POTENTIAL
Lewis, D. B., & Wilson, C. B. (1990). GAMMA-INTERFERON - AN IMMUNOREGULATORY LYMPHOKINE WITH IMMUNOTHERAPEUTIC POTENTIAL. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 9(9), 642-651.

REGULATION OF IMMUNOGLOBULIN (IG)E SYNTHESIS IN THE HYPER-IGE SYNDROME
Vercelli, D., Jabara, H. H., CUNNINGHAMRUNDLES, C., Abrams, J. S., Lewis, D. B., & Geha, R. S. (1990). REGULATION OF IMMUNOGLOBULIN (IG)E SYNTHESIS IN THE HYPER-IGE SYNDROME. JOURNAL OF CLINICAL INVESTIGATION, 85(5), 1666-1671.

BASIS AND IMPLICATIONS OF SELECTIVELY DIMINISHED CYTOKINE PRODUCTION IN NEONATAL SUSCEPTIBILITY TO INFECTION
Wilson, C. B., & Lewis, D. B. (1990). BASIS AND IMPLICATIONS OF SELECTIVELY DIMINISHED CYTOKINE PRODUCTION IN NEONATAL SUSCEPTIBILITY TO INFECTION. REVIEWS OF INFECTIOUS DISEASES, 12, S410-S420.

LYMPHOCYTE-ACTIVATION PROVOKES MODIFICATION OF A LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE (P56LCK)
Marth, J. D., Lewis, D. B., Cooke, M. P., Mellins, E. D., GEARN, M. E., & Perlmutter, R. M. (1989). LYMPHOCYTE-ACTIVATION PROVOKES MODIFICATION OF A LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE (P56LCK). JOURNAL OF IMMUNOLOGY, 142(7), 2430-2437.

RESTRICTED PRODUCTION OF INTERLEUKIN-4 BY ACTIVATED HUMAN T-CELLS
Lewis, D. B., Prickett, K. S., Larsen, A., Grabstein, K., Weaver, M., & Wilson, C. B. (1988). RESTRICTED PRODUCTION OF INTERLEUKIN-4 BY ACTIVATED HUMAN T-CELLS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 85(24), 9743-9747.

STRUCTURE AND EXPRESSION OF ICK - TRANSCRIPTS IN HUMAN LYMPHOID-CELLS
Perlmutter, R. M., Marth, J. D., Lewis, D. B., Peet, R., Ziegler, S. F., & Wilson, C. B. (1988). STRUCTURE AND EXPRESSION OF ICK - TRANSCRIPTS IN HUMAN LYMPHOID-CELLS. JOURNAL OF CELLULAR BIOCHEMISTRY, 38(2), 117-126.

REGULATION OF PP56LCK DURING T-CELL ACTIVATION - FUNCTIONAL IMPLICATIONS FOR THE SRC-LIKE PROTEIN TYROSINE KINASES
Marth, J. D., Lewis, D. B., Wilson, C. B., GEARN, M. E., Krebs, E. G., & Perlmutter, R. M. (1987). REGULATION OF PP56LCK DURING T-CELL ACTIVATION - FUNCTIONAL IMPLICATIONS FOR THE SRC-LIKE PROTEIN TYROSINE KINASES. EMBO JOURNAL, 6(9), 2727-2734.

NOVEL PROTEIN-TYROSINE KINASE GENE (HCK) PREFERENTIALLY EXPRESSED IN CELLS OF HEMATOPOIETIC ORIGIN
Ziegler, S. F., Marth, J. D., Lewis, D. B., & Perlmutter, R. M. (1987). NOVEL PROTEIN-TYROSINE KINASE GENE (HCK) PREFERENTIALLY EXPRESSED IN CELLS OF HEMATOPOIETIC ORIGIN. MOLECULAR AND CELLULAR BIOLOGY, 7(6), 2276-2285.

REDUCED INTERFERON-GAMMA MESSENGER-RNA LEVELS IN HUMAN NEONATES - EVIDENCE FOR AN INTRINSIC T-CELL DEFICIENCY INDEPENDENT OF OTHER GENES INVOLVED IN T-CELL ACTIVATION
Lewis, D. B., Larsen, A., & Wilson, C. B. (1986). REDUCED INTERFERON-GAMMA MESSENGER-RNA LEVELS IN HUMAN NEONATES - EVIDENCE FOR AN INTRINSIC T-CELL DEFICIENCY INDEPENDENT OF OTHER GENES INVOLVED IN T-CELL ACTIVATION. JOURNAL OF EXPERIMENTAL MEDICINE, 163(4), 1018-1023.

DECREASED PRODUCTION OF INTERFERON-GAMMA BY HUMAN NEONATAL CELLS - INTRINSIC AND REGULATORY DEFICIENCIES
Wilson, C. B., Westall, J., Johnston, L., Lewis, D. B., Dower, S. K., & ALPERT, A. R. (1986). DECREASED PRODUCTION OF INTERFERON-GAMMA BY HUMAN NEONATAL CELLS - INTRINSIC AND REGULATORY DEFICIENCIES. JOURNAL OF CLINICAL INVESTIGATION, 77(3), 860-867.