Quynh-Thu Le, MD

Radiation oncologist

Quynh-Thu Le, MD received both her medical school and radiation oncology training at the University of California, San Francisco (UCSF). She then joined the Stanford faculty in 1997. She became the Chair of the Stanford Radiation Oncology Department in September 2011. She also holds the Katharine Dexter McCormick & Stanley Memorial Professorship at Stanford University.

Her research focuses on translating laboratory findings to the clinic and vice versa in head and neck cancer (HNC), specifically in the area of tumor hypoxia and salivary gland stem cells. Her research is reflected in both her publications and grant funding. Hers was one of the first groups that identified circulating biomarkers for tumor hypoxia in HNC, leading to the application of some of these markers in clinical trials, testing hypoxia targeted strategies. On the clinical side, she has led multicenter phase II and III clinical trials, testing the addition of novel drugs as either radiosensitizer or radioprotector with chemoradiotherapy in HNC. She has received grant support from the American Society of Clinical Oncology (ASCO), the American Society of Therapeutic Radiology and Oncology (ASTRO) Education & Development Award, R01 and R21 grants from the National Institute of Health (NIH). She was inducted into the Fellowship of the American College of Radiology (FACR) and the Institute of Medicine (IOM).

Administratively, she is the Co-Director of the Radiation Biology Program of the Stanford Cancer Institute and is the current Chair of the ASTRO Educational Committee. She is also the Chair of the Head and Neck Cancer Committee of the Radiation Therapy Oncology Group (RTOG), which is a NCI funded cooperative group, running large phase II-III studies for radiation in solid cancers. She serves on the editorial board of the several cancer related journals.

Radiation Oncology

  • 875 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

Cyberknife Stereotactic Radiosurgery Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-725-0084
Learn More About the Clinic Getting Here Make An Appointment

Head and Neck Cancer Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

Cranial Base Center

  • 801 Welch Road
  • Stanford, CA 94305
  • Phone: 650-723-5281
Learn More About the Clinic Getting Here Make An Appointment

Cyberknife Stereotactic Radiosurgery Program at Advanced Medicine Center Building

  • 875 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-725-0084
Learn More About the Clinic Getting Here Make An Appointment

Cyberknife Stereotactic Radiosurgery Program at Boswell Building

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-725-0084
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Internship: Highland General Hospital (1994) CA

Board Certification: Radiation Oncology, American Board of Radiology (1998)

Residency: UCSF Medical Center (1997) CA

Medical Education: UCSF School of Medicine (1993) CA

MD, UCSF, Medicine (1993)

Administrative Appointments

Co-Director, Radiation Biology Program, Stanford Cancer Institute, 2004

Chair, Department of Radiation Oncology, Stanford University, 2011

Director of Clinial research, Department of radiation oncology, stanford university, 2005

Long-Term Outcomes of Surgery Followed by Radiation Therapy for Minor Salivary Gland Carcinomas
Zeidan, Y. H., Shultz, D. B., Murphy, J. D., Chan, C., Kaplan, M. J., & Le, Q.-T. (2013). Long-Term Outcomes of Surgery Followed by Radiation Therapy for Minor Salivary Gland Carcinomas. LARYNGOSCOPE, 123(11), 2675-2680.

Clinical impact of dose overestimation by effective path length calculation in stereotactic ablative radiation therapy of lung tumors.
Liu, M. B., Eclov, N. Cw., Trakul, N., Murphy, J., Diehn, M., & Loo, B. W. (2013). Clinical impact of dose overestimation by effective path length calculation in stereotactic ablative radiation therapy of lung tumors. Practical radiation oncology, 3(4), 294-300.

Radiotherapy for nonadenoid cystic carcinomas of major salivary glands.
Chung, M. P., Tang, C., Chan, C., Hara, W. Y., Loo, B. W., & Chang, D. T. (2013). Radiotherapy for nonadenoid cystic carcinomas of major salivary glands. American journal of otolaryngology, 34(5), 425-430.

A novel aldehyde dehydrogenase-3 activator (Alda-89) protects submandibular gland function from irradiation without accelerating tumor growth.
Xiao, N., Cao, H., Chen, C.-H., Kong, C. S., Ali, R., & Le, Q.-T. (2013). A novel aldehyde dehydrogenase-3 activator (Alda-89) protects submandibular gland function from irradiation without accelerating tumor growth. Clinical cancer research , 19(16), 4455-4464.

Low-dose radiation therapy (2 Gy × 2) in the treatment of orbital lymphoma.
Fasola, C. E., Jones, J. C., Huang, D. D., Le, Q.-T., Hoppe, R. T., & Donaldson, S. S. (2013). Low-dose radiation therapy (2 Gy × 2) in the treatment of orbital lymphoma. International journal of radiation oncology, biology, physics, 86(5), 930-935.

Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy.
Sasportas, L. S., Hosford, D. N., Sodini, M. A., Waters, D. J., Zambricki, E. A., & Sirjani, D. (2013). Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy. Oral surgery, oral medicine, oral pathology and oral radiology, 116(1), e37-51.

Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck.
Tang, C., Fischbein, N. J., Murphy, J. D., Chu, K. P., Bavan, B., & Le, Q.-T. (2013). Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck. American journal of clinical oncology, 36(3), 293-298.

Opportunities and challenges in the era of molecularly targeted agents and radiation therapy.
Lin, S. H., George, T. J., Ben-Josef, E., Bradley, J., Choe, K. S., & Chung, C. H. (2013). Opportunities and challenges in the era of molecularly targeted agents and radiation therapy. Journal of the National Cancer Institute, 105(10), 686-693.

An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma.
Le, Q.-T., Zhang, Q., Cao, H., Cheng, A.-J., Pinsky, B. A., & Chan, K. Ca. (2013). An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma. Clinical cancer research , 19(8), 2208-2215.

Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence
Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., & Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. CANCER, 119(7), 1349-1356.

Volumetric-Modulated Arc Radiotherapy for Skull-Base and Non-Skull-Base Head and Neck Cancer: A Treatment Planning Comparison with Fixed Beam IMRT
Chen, J., Mok, E., Wang, L., Chen, C., & Quynh-Thu Le, Q. T. (2013). Volumetric-Modulated Arc Radiotherapy for Skull-Base and Non-Skull-Base Head and Neck Cancer: A Treatment Planning Comparison with Fixed Beam IMRT. TECHNOLOGY IN CANCER RESEARCH & TREATMENT, 12(1), 11-18.

Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy.
Hong, J. C., Eclov, N. Cw., Yu, Y., Rao, A. K., Dieterich, S., & Maxim, P. G. (2013). Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. Journal of applied clinical medical physics , 14(2), 4046-?.

Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse.
Kong, C. S., Cao, H., Kwok, S., Nguyen, C. M., Jordan, R. C., & Le, Q.-T. (2013). Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse. Oral surgery, oral medicine, oral pathology and oral radiology, 115(1), 95-103.

Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy.
Abelson, J. A., Murphy, J. D., Trakul, N., Bazan, J. G., Maxim, P. G., & Loo, B. W. (2012). Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy. Lung cancer , 78(3), 219-224.

CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma
Janisiewicz, A. M., Shin, J. H., Murillo-Sauca, O., Kwok, S., Quynh-Thu Le, Q. T., & Sunwoo, J. B. (2012). CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(6), 465-470.

Esophageal tolerance to high-dose stereotactic ablative radiotherapy
Abelson, J. A., Murphy, J. D., Loo, B. W., Chang, D. T., Daly, M. E., & Gibbs, I. C. (2012). Esophageal tolerance to high-dose stereotactic ablative radiotherapy. DISEASES OF THE ESOPHAGUS, 25(7), 623-629.

Stereotactic Ablative Radiotherapy for Reirradiation of Locally Recurrent Lung Tumors
Trakul, N., Harris, J. P., Le, Q.-T., Hara, W. Y., Maxim, P. G., & Diehn, M. (2012). Stereotactic Ablative Radiotherapy for Reirradiation of Locally Recurrent Lung Tumors. JOURNAL OF THORACIC ONCOLOGY, 7(9), 1462-1465.

Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors
Trakul, N., Chang, C. N., Harris, J., Chapman, C., Rao, A., & Diehn, M. (2012). Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(1), 231-237.

Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images
Li, R., Mok, E., Chang, D. T., Daly, M., Loo, B. W., & Xing, L. (2012). Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), E709-E715.

Evaluation of ProExC as a Prognostic Marker in Oropharyngeal Squamous Cell Carcinomas
Mills, A. M., Beck, A. H., Pourmand, N., Quynh Thu Le, Q. T., & Kong, C. S. (2012). Evaluation of ProExC as a Prognostic Marker in Oropharyngeal Squamous Cell Carcinomas. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 36(8), 1158-1164.

Validation that Metabolic Tumor Volume Predicts Outcome in Head-and-Neck Cancer
Tang, C., Murphy, J. D., Khong, B., La, T. H., Kong, C., & Quynh-Thu Le, Q. T. (2012). Validation that Metabolic Tumor Volume Predicts Outcome in Head-and-Neck Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), 1514-1520.

Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head-and-Neck Cancer Outcomes
Chu, K. P., Murphy, J. D., La, T. H., Krakow, T. E., Iagaru, A., & Quynh-Thu Le, Q. T. (2012). Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head-and-Neck Cancer Outcomes. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), 1521-1527.

A Planned Neck Dissection Is Not Necessary in All Patients With N2-3 Head-and-Neck Cancer After Sequential Chemoradiotherapy
Soltys, S. G., Choi, C. Yh., Fee, W. E., Pinto, H. A., & Le, Q.-T. (2012). A Planned Neck Dissection Is Not Necessary in All Patients With N2-3 Head-and-Neck Cancer After Sequential Chemoradiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(3), 994-999.

Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure
Wiegner, E. A., Daly, M. E., Murphy, J. D., Abelson, J., Chapman, C. H., & Chang, D. T. (2012). Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(1), 243-251.

Prognostic and Predictive Significance of Plasma HGF and IL-8 in a Phase III Trial of Chemoradiation with or without Tirapazamine in Locoregionally Advanced Head and Neck Cancer
Quynh-Thu Le, Q. T., Fisher, R., Oliner, K. S., Young, R. J., Cao, H., & Rischin, D. (2012). Prognostic and Predictive Significance of Plasma HGF and IL-8 in a Phase III Trial of Chemoradiation with or without Tirapazamine in Locoregionally Advanced Head and Neck Cancer. CLINICAL CANCER RESEARCH, 18(6), 1798-1807.

Quantitation of Human Papillomavirus DNA in Plasma of Oropharyngeal Carcinoma Patients
Cao, H., Banh, A., Kwok, S., Shi, X., Wu, S., & Quynh-Thu Le, Q. T. (2012). Quantitation of Human Papillomavirus DNA in Plasma of Oropharyngeal Carcinoma Patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 82(3), E351-E358.

Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial
Lee, N. Y., Zhang, Q., Pfister, D. G., Kim, J., Garden, A. S., & Ang, K. K. (2012). Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial. LANCET ONCOLOGY, 13(2), 172-180.

Prognostic Significance of Plasma Osteopontin in Patients with Locoregionally Advanced Head and Neck Squamous Cell Carcinoma Treated on TROG 02.02 Phase III Trial
Lim, A. M., Rischin, D., Fisher, R., Cao, H., Kwok, K., & Le, Q.-T. (2012). Prognostic Significance of Plasma Osteopontin in Patients with Locoregionally Advanced Head and Neck Squamous Cell Carcinoma Treated on TROG 02.02 Phase III Trial. CLINICAL CANCER RESEARCH, 18(1), 301-307.

Salvage Treatment for Locally Recurrent Nasopharyngeal Carcinoma (NPC).
Chen, C., Fee, W., Chen, J., Chan, C., Khong, B., & Le, Q. T. (2012). Salvage Treatment for Locally Recurrent Nasopharyngeal Carcinoma (NPC). American journal of clinical oncology.

Metabolic Tumor Volume is an Independent Prognostic Factor in Patients Treated Definitively for Non-Small-Cell Lung Cancer
Lee, P., Bazan, J. G., Lavori, P. W., Weerasuriya, D. K., Quon, A., & Loo, B. W. (2012). Metabolic Tumor Volume is an Independent Prognostic Factor in Patients Treated Definitively for Non-Small-Cell Lung Cancer. CLINICAL LUNG CANCER, 13(1), 52-58.

A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo
Banh, A., Xiao, N., Cao, H., Chen, C.-H., Kuo, P., & Quynh-Thu Le, Q. T. (2011). A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo. CLINICAL CANCER RESEARCH, 17(23), 7265-7272.

Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity
Murphy, J. D., Chisholm, K. M., Daly, M. E., Wiegner, E. A., Truong, D., & Le, Q.-T. (2011). Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity. RADIOTHERAPY AND ONCOLOGY, 101(3), 356-361.

ON-BOARD IMAGING VALIDATION OF OPTICALLY GUIDED STEREOTACTIC RADIOSURGERY POSITIONING SYSTEM FOR CONVENTIONALLY FRACTIONATED RADIOTHERAPY FOR PARANASAL SINUS AND SKULL BASE CANCER
Maxim, P. G., Loo, B. W., Murphy, J. D., Chu, K. Pm., Hsu, A., & Quynh-Thu Le, Q. T. (2011). ON-BOARD IMAGING VALIDATION OF OPTICALLY GUIDED STEREOTACTIC RADIOSURGERY POSITIONING SYSTEM FOR CONVENTIONALLY FRACTIONATED RADIOTHERAPY FOR PARANASAL SINUS AND SKULL BASE CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(4), 1153-1159.

HIGH RETENTION AND SAFETY OF PERCUTANEOUSLY IMPLANTED ENDOVASCULAR EMBOLIZATION COILS AS FIDUCIAL MARKERS FOR IMAGE-GUIDED STEREOTACTIC ABLATIVE RADIOTHERAPY OF PULMONARY TUMORS
Hong, J. C., Yu, Y., Rao, A. K., Ditererich, S., Maxim, P. G., & Loo, B. W. (2011). HIGH RETENTION AND SAFETY OF PERCUTANEOUSLY IMPLANTED ENDOVASCULAR EMBOLIZATION COILS AS FIDUCIAL MARKERS FOR IMAGE-GUIDED STEREOTACTIC ABLATIVE RADIOTHERAPY OF PULMONARY TUMORS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(1), 85-90.

Results from a Single Institution Phase II Trial of Concurrent Docetaxel/Carboplatin/Radiotherapy Followed by Surgical Resection and Consolidation Docetaxel/Carboplatin in Stage III Non-Small-Cell Lung Cancer
Das, M., Donington, J. S., Murphy, J., Kozak, M., Eclov, N., & Wakelee, H. (2011). Results from a Single Institution Phase II Trial of Concurrent Docetaxel/Carboplatin/Radiotherapy Followed by Surgical Resection and Consolidation Docetaxel/Carboplatin in Stage III Non-Small-Cell Lung Cancer. CLINICAL LUNG CANCER, 12(5), 280-285.

INTENSITY-MODULATED RADIOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA: PATTERNS OF FAILURE AND PREDICTORS OF LOCAL CONTROL
Daly, M. E., Quynh-Thu Le, Q. T., Kozak, M. M., Maxim, P. G., Murphy, J. D., & Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA: PATTERNS OF FAILURE AND PREDICTORS OF LOCAL CONTROL. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 80(5), 1412-1422.

Palifermin Reduces Severe Mucositis in Definitive Chemoradiotherapy of Locally Advanced Head and Neck Cancer: A Randomized, Placebo-Controlled Study
Le, Q.-T., Kim, H. E., Schneider, C. J., Murakozy, G., Skladowski, K., & Henke, M. (2011). Palifermin Reduces Severe Mucositis in Definitive Chemoradiotherapy of Locally Advanced Head and Neck Cancer: A Randomized, Placebo-Controlled Study. JOURNAL OF CLINICAL ONCOLOGY, 29(20), 2808-2814.

Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis
Banh, A., Zhang, J., Cao, H., Bouley, D. M., Kwok, S., & Le, Q.-T. (2011). Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis. CANCER RESEARCH, 71(13), 4423-4431.

POSTRADIATION METABOLIC TUMOR VOLUME PREDICTS OUTCOME IN HEAD-AND-NECK CANCER
Murphy, J. D., La, T. H., Chu, K., Quon, A., Fischbein, N. J., & Le, Q.-T. (2011). POSTRADIATION METABOLIC TUMOR VOLUME PREDICTS OUTCOME IN HEAD-AND-NECK CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 80(2), 514-521.

Head and Neck Cancer-Specific Survival Based on Socioeconomic Status in Asians and Pacific Islanders
Chu, K. P., Shema, S., Wu, S., Gomez, S. L., Chang, E. T., & Quynh-Thu Le, Q. T. (2011). Head and Neck Cancer-Specific Survival Based on Socioeconomic Status in Asians and Pacific Islanders. CANCER, 117(9), 1935-1945.

Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer
Kozak, M. M., Murphy, J. D., Schipper, M. L., Donington, J. S., Zhou, L., & Loo, B. W. (2011). Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 6(5), 920-926.

Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003)
Chung, C. H., Dignam, J. J., Hammond, M. E., Klimowicz, A. C., Petrillo, S. K., & Ang, K. K. (2011). Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003). JOURNAL OF CLINICAL ONCOLOGY, 29(10), 1326-1333.

MYB Expression and Translocation in Adenoid Cystic Carcinomas and Other Salivary Gland Tumors With Clinicopathologic Correlation
West, R. B., Kong, C., Clarke, N., Gilks, T., Lipsick, J. S., & Le, Q.-T. (2011). MYB Expression and Translocation in Adenoid Cystic Carcinomas and Other Salivary Gland Tumors With Clinicopathologic Correlation. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 35(1), 92-99.

INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX
Daly, M. E., Le, Q.-T., Jain, A. K., Maxim, P. G., Hsu, A., & Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 33(1), 103-111.

Intensity-Modulated and Image-Guided Radiation Therapy for Head and Neck Cancers
Chu, K. P.-M., & Le, Q.-T. (2011). Intensity-Modulated and Image-Guided Radiation Therapy for Head and Neck Cancers. IMRT IGRT SBRT- ADVANCES IN THE TREATMENT PLANNING AND DELIVERY OF RADIOTHERAPY, 43, 217-254.

HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA
Filion, E. J., McClure, L. A., Huang, D., Seng, K., Kaplan, M. J., & Le, Q.-T. (2010). HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 32(10), 1336-1344.

Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics
Graves, E. E., Vilalta, M., Cecic, I. K., Erler, J. T., Tran, P. T., & Giaccia, A. J. (2010). Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics. CLINICAL CANCER RESEARCH, 16(19), 4843-4852.

Prognostic Significance of p16(INK4A) and Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial
Rischin, D., Young, R. J., Fisher, R., Fox, S. B., Le, Q.-T., & McArthur, G. A. (2010). Prognostic Significance of p16(INK4A) and Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial. JOURNAL OF CLINICAL ONCOLOGY, 28(27), 4142-4148.

Dose reconstruction for volumetric modulated arc therapy (VMAT) using cone-beam CT and dynamic log files
Qian, J., Lee, L., Liu, W., Chu, K., Mok, E., & Xing, L. (2010). Dose reconstruction for volumetric modulated arc therapy (VMAT) using cone-beam CT and dynamic log files. PHYSICS IN MEDICINE AND BIOLOGY, 55(13), 3597-3610.

The Tumor Microenvironment in Non-Small-Cell Lung Cancer
Graves, E. E., Maity, A., & Le, Q.-T. (2010). The Tumor Microenvironment in Non-Small-Cell Lung Cancer. SEMINARS IN RADIATION ONCOLOGY, 20(3), 156-163.

MiR-210-micromanager of the hypoxia pathway
Huang, X., Le, Q.-T., & Giaccia, A. J. (2010). MiR-210-micromanager of the hypoxia pathway. TRENDS IN MOLECULAR MEDICINE, 16(5), 230-237.

Image-based modeling of tumor shrinkage in head and neck radiation therapy
Chao, M., Xie, Y., Moros, E. G., Le, Q.-T., & Xing, L. (2010). Image-based modeling of tumor shrinkage in head and neck radiation therapy. MEDICAL PHYSICS, 37(5), 2351-2358.

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer
Ho, A. S., Huang, X., Cao, H., Christman-Skieller, C., Bennewith, K., & Koong, A. C. (2010). Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer. TRANSLATIONAL ONCOLOGY, 3(2), 109-113.

Cetuximab-Based Immunotherapy and Radioimmunotherapy of Head and Neck Squamous Cell Carcinoma
Niu, G., Sun, X., Cao, Q., Courter, D., Koong, A., & Chen, X. (2010). Cetuximab-Based Immunotherapy and Radioimmunotherapy of Head and Neck Squamous Cell Carcinoma. CLINICAL CANCER RESEARCH, 16(7), 2095-2105.

INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF OROPHARYNGEAL CANCER: CLINICAL OUTCOMES AND PATTERNS OF FAILURE
Daly, M. E., Le, Q.-T., Maxim, P. G., Loo, B. W., Kaplan, M. J., & Chang, D. T. (2010). INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF OROPHARYNGEAL CANCER: CLINICAL OUTCOMES AND PATTERNS OF FAILURE. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 76(5), 1339-1346.

The RGD Domain of Human Osteopontin Promotes Tumor Growth and Metastasis through Activation of Survival Pathways
Courter, D., Cao, H., Kwok, S., Kong, C., Banh, A., & Le, Q.-T. (2010). The RGD Domain of Human Osteopontin Promotes Tumor Growth and Metastasis through Activation of Survival Pathways. PLOS ONE, 5(3).

Imaging the Unfolded Protein Response in Primary Tumors Reveals Microenvironments with Metabolic Variations that Predict Tumor Growth
Spiotto, M. T., Banh, A., Papandreou, I., Cao, H., Galvez, M. G., & Koong, A. C. (2010). Imaging the Unfolded Protein Response in Primary Tumors Reveals Microenvironments with Metabolic Variations that Predict Tumor Growth. CANCER RESEARCH, 70(1), 78-88.

Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
Chang, S. T., Zahn, J. M., Horecka, J., Kunz, P. L., Ford, J. M., & Koong, A. C. (2009). Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis. JOURNAL OF TRANSLATIONAL MEDICINE, 7.

COMPARISON OF TREATMENT RESULTS BETWEEN ADULT AND JUVENILE NASOPHARYNGEAL CARCINOMA
Downing, N. L., Wolden, S., Wong, P., Petrik, D. W., Hara, W., & Le, Q.-T. (2009). COMPARISON OF TREATMENT RESULTS BETWEEN ADULT AND JUVENILE NASOPHARYNGEAL CARCINOMA. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 75(4), 1064-1070.

Mucositis-Related Morbidity and Resource Utilization in Head and Neck Cancer Patients Receiving Radiation Therapy With or Without Chemotherapy
Murphy, B. A., Beaumont, J. L., Isitt, J., Garden, A. S., Gwede, C. K., & Cella, D. (2009). Mucositis-Related Morbidity and Resource Utilization in Head and Neck Cancer Patients Receiving Radiation Therapy With or Without Chemotherapy. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 38(4), 522-532.

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation
Huang, X., Ding, L., Bennewith, K. L., Tong, R. T., Welford, S. M., & Giaccia, A. J. (2009). Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation. MOLECULAR CELL, 35(6), 856-867.

Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03
Le, Q.-T., Harris, J., Magliocco, A. M., Kong, C. S., Diaz, R., & Ang, K. K. (2009). Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03. JOURNAL OF CLINICAL ONCOLOGY, 27(26), 4281-4286.

METABOLIC TUMOR VOLUME PREDICTS FOR RECURRENCE AND DEATH IN HEAD-AND-NECK CANCER
La, T. H., Filion, E. J., Turnbull, B. B., Chu, J. N., Lee, P., & Le, Q.-T. (2009). METABOLIC TUMOR VOLUME PREDICTS FOR RECURRENCE AND DEATH IN HEAD-AND-NECK CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 74(5), 1335-1341.

PET of EGFR Antibody Distribution in Head and Neck Squamous Cell Carcinoma Models
Niu, G., Li, Z., Xie, J., Le, Q.-T., & Chen, X. (2009). PET of EGFR Antibody Distribution in Head and Neck Squamous Cell Carcinoma Models. JOURNAL OF NUCLEAR MEDICINE, 50(7), 1116-1123.

THE RELATIONSHIP BETWEEN HUMAN PAPILLOMAVIRUS STATUS AND OTHER MOLECULAR PROGNOSTIC MARKERS IN HEAD AND NECK SQUAMOUS CELL CARCINOMAS
Kong, C. S., Narasimhan, B., Cao, H., Kwok, S., Erickson, J. P., & Le, Q.-T. (2009). THE RELATIONSHIP BETWEEN HUMAN PAPILLOMAVIRUS STATUS AND OTHER MOLECULAR PROGNOSTIC MARKERS IN HEAD AND NECK SQUAMOUS CELL CARCINOMAS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 74(2), 553-561.

XBP-1 regulates angiogenesis in human pancreatic adenocarcinomas
Romero-Ramirez, L., Cao, H., Regalado, M. P., Kambham, N., Siemann, D., & Koong, A. C. (2009). XBP-1 regulates angiogenesis in human pancreatic adenocarcinomas. TRANSLATIONAL ONCOLOGY, 2(1), 31-U42.

X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas.
Romero-Ramirez, L., Cao, H., Regalado, M. P., Kambham, N., Siemann, D., & Koong, A. C. (2009). X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas. Translational oncology, 2(1), 31-38.

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
Erler, J. T., Bennewith, K. L., Cox, T. R., Lang, G., Bird, D., & Giaccia, A. J. (2009). Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche. CANCER CELL, 15(1), 35-44.

Integrating Biologically Targeted Therapy in Head and Neck Squamous Cell Carcinomas
Le, Q.-T., & Rabent, D. (2009). Integrating Biologically Targeted Therapy in Head and Neck Squamous Cell Carcinomas. SEMINARS IN RADIATION ONCOLOGY, 19(1), 53-62.

Lower osteopontin plasma levels are associated with superior outcomes in advanced non-small-cell lung cancer patients receiving platinum-based chemotherapy: SWOG study S0003
Mack, P. C., Redman, M. W., Chansky, K., Williamson, S. K., Farneth, N. C., & Gandara, D. R. (2008). Lower osteopontin plasma levels are associated with superior outcomes in advanced non-small-cell lung cancer patients receiving platinum-based chemotherapy: SWOG study S0003. JOURNAL OF CLINICAL ONCOLOGY, 26(29), 4771-4776.

Clinical biomarkers for hypoxia targeting
Le, Q.-T., & Courter, D. (2008). Clinical biomarkers for hypoxia targeting. CANCER AND METASTASIS REVIEWS, 27(3), 351-362.

In vivo H-1 magnetic resonance spectroscopy of lactate in patients with Stage IV head and neck squamous cell carcinoma
Le, Q.-T., Koong, A., Lieskovsky, Y. Y., Narasimhan, B., Graves, E., & Spielman, D. (2008). In vivo H-1 magnetic resonance spectroscopy of lactate in patients with Stage IV head and neck squamous cell carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 71(4), 1151-1157.

Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma
Hara, W., Loo, B. W., Goffinet, D. R., Chang, S. D., Adler, J. R., & Le, Q.-T. (2008). Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 71(2), 393-400.

Molecular Imaging of Hypoxia-Inducible Factor 1 alpha and von Hippel-Lindau Interaction in Mice
Choi, C. Yh., Chau, D. A., Paulmurugan, R., Sutphin, P. D., Le, Q.-T., & Giaccia, A. J. (2008). Molecular Imaging of Hypoxia-Inducible Factor 1 alpha and von Hippel-Lindau Interaction in Mice. MOLECULAR IMAGING, 7(3), 139-146.

LINAC-based on-board imaging feasibility and the dosimetric consequences of head roll in head-and-neck IMRT plans
Kim, G.-Y., Pawlicki, T., Le, Q.-T., & Luxton, G. (2008). LINAC-based on-board imaging feasibility and the dosimetric consequences of head roll in head-and-neck IMRT plans. MEDICAL DOSIMETRY, 33(1), 93-99.

Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file
Lee, L., Le, Q.-T., & Xing, L. (2008). Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 70(2), 634-644.

Quantification of motion of different thoracic locations using four-dimensional computed tomography: Implications for radiotherapy planning
Maxim, P. G., Loo, B. W., Shirazi, H., Thorndyke, B., Luxton, G., & Le, Q.-T. (2007). Quantification of motion of different thoracic locations using four-dimensional computed tomography: Implications for radiotherapy planning. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(5), 1395-1401.

Metabolic tumor burden predicts for disease progression and death in lung cancer
Lee, P., Weerasuriya, D. K., Lavori, P. W., Quon, A., Hara, W., & Loo, B. W. (2007). Metabolic tumor burden predicts for disease progression and death in lung cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(2), 328-333.

Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas
Le, Q.-T., Kong, C., Lavori, P. W., O'Byrne, K., Erler, J. T., & Koong, A. C. (2007). Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(1), 167-175.

Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire
Epstein, J. B., Beaumont, J. L., Gwede, C. K., Murphy, B., Garden, A. S., & Cella, D. (2007). Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire. CANCER, 109(9), 1914-1922.

Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma
Daly, M. E., Lieskovsky, Yy., Pawlicki, T., Yau, J., Pinto, H., & Le, Q.-T. (2007). Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 29(3), 211-220.

Identifying and targeting hypoxia in head and neck cancer: A brief overview of current approaches
Le, Q.-T. (2007). Identifying and targeting hypoxia in head and neck cancer: A brief overview of current approaches. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(2), S56-S58.

Nasopharyngeal and oropharyngeal carcinomas: Target delineation, therapy delivery and stereotactic boost procedures with intensity-modulated/image-guided radiation therapy
Le, Q.-T. (2007). Nasopharyngeal and oropharyngeal carcinomas: Target delineation, therapy delivery and stereotactic boost procedures with intensity-modulated/image-guided radiation therapy. IMRT, IGRT, SBRT: ADVANCES IN THE TREATMENT PLANNING AND DELIVERY OF RADIOTHERAPY, 40, 208-231.

Clinical role of F-18-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma
Quon, A., Fischbein, N. J., McDougall, I. R., Le, Q.-T., Loo, B. W., & Kaplan, M. J. (2007). Clinical role of F-18-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma. JOURNAL OF NUCLEAR MEDICINE, 48, 58S-67S.

Plasma osteopontin is an independent prognostic marker for head and neck cancers
Petrik, D., Lavori, P. W., Cao, H., Zhu, Y., Wong, P., & Le, Q.-T. (2006). Plasma osteopontin is an independent prognostic marker for head and neck cancers. JOURNAL OF CLINICAL ONCOLOGY, 24(33), 5291-5297.

Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors
Le, Q.-T., Loo, B. W., Ho, A., Cotrutz, C., Koong, A. C., & Donington, J. (2006). Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors. JOURNAL OF THORACIC ONCOLOGY, 1(8), 802-809.

Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: A pilot study in humans
Loo, B. W., Draney, M. T., Sivanandan, R., Ruehm, S. G., Pawlicki, T., & Le, Q.-T. (2006). Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: A pilot study in humans. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 66(2), 462-468.

A multidisciplinary approach to management in a patient with bilateral superior sulcus non-small-cell lung carcinoma
Roy, M. S., Le, Q.-T., Donington, J. S., & Wakelee, H. A. (2006). A multidisciplinary approach to management in a patient with bilateral superior sulcus non-small-cell lung carcinoma. CLINICAL LUNG CANCER, 8(2), 146-148.

Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site
Shirazi, H. A., Sivanandan, R., Goode, R., Fee, W. E., Kaplan, M. J., & Le, Q.-T. (2006). Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 28(7), 587-594.

Lung cancer in women: Exploring sex differences in susceptibility, biology, and therapeutic response
Donington, J. S., Le, Q.-T., & Wakelee, H. A. (2006). Lung cancer in women: Exploring sex differences in susceptibility, biology, and therapeutic response. CLINICAL LUNG CANCER, 8(1), 22-29.

Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis
Dornhoefer, N., Spong, S., Bennewith, K., Salim, A., Klaus, S., & Giaccia, A. (2006). Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. CANCER RESEARCH, 66(11), 5816-5827.

Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV head and neck squamous cell carcinomas
Le, Q. T., Taira, A. I., Budenz, S., Dorie, M. J., Goffinet, D. R., & Pinto, H. A. (2006). Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV head and neck squamous cell carcinomas. CANCER, 106(9), 1940-1949.

Lysyl oxidase is essential for hypoxia-induced metastasis
Erler, J. T., Bennewith, K. L., Nicolau, M., Dornhofer, N., Kong, C., & Giaccia, A. J. (2006). Lysyl oxidase is essential for hypoxia-induced metastasis. NATURE, 440(7088), 1222-1226.

An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers
Le, Q. T., Chen, E., Salim, A., Cao, H. B., Kong, C. S., & Giaccia, A. J. (2006). An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. CLINICAL CANCER RESEARCH, 12(5), 1507-1514.

Comment on: Osteopontin as toxic marker
Le, Q. T., Cao, H. B., & Giaccia, A. (2006). Comment on: Osteopontin as toxic marker. RADIOTHERAPY AND ONCOLOGY, 78(2), 230-230.

Galectin-1: A link between tumor hypoxia and tumor immune privilege
Le, Q. T., Shi, G. Y., Cao, H. B., Nelson, D. W., Wang, Y. Y., & Koong, A. C. (2005). Galectin-1: A link between tumor hypoxia and tumor immune privilege. JOURNAL OF CLINICAL ONCOLOGY, 23(35), 8932-8941.

Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae
Chen, Y. J., Feldman, D. E., Deng, C. C., BROWN, J. A., De Giacomo, A. F., & Koong, A. C. (2005). Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. MOLECULAR CANCER RESEARCH, 3(12), 669-677.

Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
Koong, A. C., Christofferson, E., Le, Q. T., Goodman, K. A., Ho, A., & Yang, G. P. (2005). Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(2), 320-323.

Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a ras-activated enhancer
Zhu, Y. H., Denhardt, D. T., Cao, H. B., Sutphin, P. D., Koong, A. C., & Le, Q. T. (2005). Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a ras-activated enhancer. ONCOGENE, 24(43), 6555-6563.

A comparison study of different PCR assays in measuring circulating plasma Epstein-Barr virus DNA levels in patients with nasopharyngeal carcinoma
Le, Q. T., Jones, C. D., Yau, T. K., Shirazi, H. A., Wong, P. H., & Zehnder, J. L. (2005). A comparison study of different PCR assays in measuring circulating plasma Epstein-Barr virus DNA levels in patients with nasopharyngeal carcinoma. CLINICAL CANCER RESEARCH, 11(16), 5700-5707.

A noninvasive approach for assessing tumor hypoxia in xenografts: Developing a urinary marker for hypoxia
Nelson, D. W., Cao, H. B., Zhu, Y. H., Sunar-Reeder, B., Choi, C. Yh., & Le, Q. T. (2005). A noninvasive approach for assessing tumor hypoxia in xenografts: Developing a urinary marker for hypoxia. CANCER RESEARCH, 65(14), 6151-6158.

Nonsurgical therapy for stages I and II non-small cell lung cancer
Le, Q. T., & Petrik, D. W. (2005). Nonsurgical therapy for stages I and II non-small cell lung cancer. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 19(2), 237-?.

Positron-emission tomography for surveillance of head and neck cancer
Ryan, W. R., Fee, W. E., Le, Q. T., & Pinto, H. A. (2005). Positron-emission tomography for surveillance of head and neck cancer. LARYNGOSCOPE, 115(4), 645-650.

Long-term results of 100 consecutive comprehensive neck dissections - Implications for selective neck dissections
Sivanandan, R., Kaplan, M. J., Lee, K. J., Lebl, D., PINTO, H., & Fee, W. E. (2004). Long-term results of 100 consecutive comprehensive neck dissections - Implications for selective neck dissections. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 130(12), 1369-1373.

Sample classification from protein mass spectrometry, by 'peak probability contrasts'
Tibshirani, R., Hastie, T., Narasimhan, B., Soltys, S., Shi, G. Y., & Le, Q. T. (2004). Sample classification from protein mass spectrometry, by 'peak probability contrasts'. BIOINFORMATICS, 20(17), 3034-3044.

Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling
Chen, Y. J., Shi, G. Y., Wei, X., Kong, C., Zhao, S. C., & Koong, A. C. (2004). Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. CANCER RESEARCH, 64(20), 7302-7310.

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
Romero-Ramirez, L., Cao, H. B., Nelson, D., Hammond, E., Lee, A. H., & Koong, A. C. (2004). XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. CANCER RESEARCH, 64(17), 5943-5947.

Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms
Su, C. K., Mehta, V., Ravikumar, L., Shah, R., PINTO, H., & Le, Q. T. (2004). Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 60(1), 171-177.

Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): A Southwest Oncology Group Study
Le, Q. T., McCoy, J., Williamson, S., Ryu, J., Gaspar, L. E., & Gandara, D. R. (2004). Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): A Southwest Oncology Group Study. CLINICAL CANCER RESEARCH, 10(16), 5418-5424.

Hypoxic gene expression and metastasis
Le, Q. T., Denko, N. C., & Giaccia, A. J. (2004). Hypoxic gene expression and metastasis. CANCER AND METASTASIS REVIEWS, 23(3-4), 293-310.

The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers
Soltys, S. G., Le, Q. T., Shi, G. Y., Tibshirani, R., Giaccia, A. J., & Koong, A. C. (2004). The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers. CLINICAL CANCER RESEARCH, 10(14), 4806-4812.

Extranodal nonorbital indolent lymphomas of the head and neck: Relationship between tumor control and radiotherapy
MacDermed, D., Thurber, L., George, T. I., Hoppe, R. T., & Le, Q. T. (2004). Extranodal nonorbital indolent lymphomas of the head and neck: Relationship between tumor control and radiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 59(3), 788-795.

Lens dose in MLC-based IMRT treatments of the head and neck
Pawlicki, T., Luxton, G., Le, Q. T., Findley, D., & Ma, C. M. (2004). Lens dose in MLC-based IMRT treatments of the head and neck. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 59(1), 293-299.

Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer
Koong, A. C., Le, Q. T., Ho, A., Fong, B., Fisher, G., & Bastidas, J. A. (2004). Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 58(4), 1017-1021.

Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancer
Le, Q. T., & Giaccia, A. J. (2003). Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancer. CLINICAL CANCER RESEARCH, 9(12), 4287-4295.

Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers
Gibbs, I. C., Le, Q. T., Shah, R. D., Terris, D. J., Fee, W. E., & Goffinet, D. R. (2003). Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 57(2), 489-494.

Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma
Le, Q. T., Tate, D., Koong, A., Gibbs, I. C., Chang, S. D., & Goffinet, D. R. (2003). Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56(4), 1046-1054.

HIF-alpha, a gender independent transcription factor
Le, Q. T., & Giaccia, A. J. (2003). HIF-alpha, a gender independent transcription factor. CLINICAL CANCER RESEARCH, 9(7), 2391-2393.

Radiation therapy for intracranial germ cell tumors
Haas-Kogan, D. A., Missett, B. T., Wara, W. M., Donaldson, S. S., Lamborn, K. R., & Le, Q. T. (2003). Radiation therapy for intracranial germ cell tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56(2), 511-518.

Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients
Le, Q. T., Kovacs, M. S., Dorie, M. J., Koong, A., Terris, D. J., & Brown, J. M. (2003). Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56(2), 375-383.

Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial
Whyte, R. I., Crownover, R., MURPHY, M. J., Martin, D. P., Rice, T. W., & Le, Q. T. (2003). Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial. ANNALS OF THORACIC SURGERY, 75(4), 1097-1101.

Patterns of patient movement during frameless image-guided radiosurgery
Murphy, M. J., Chang, S. D., Gibbs, I. C., Le, Q. T., Hai, J., & Adler, J. R. (2003). Patterns of patient movement during frameless image-guided radiosurgery. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 55(5), 1400-1408.

Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
Le, Q. T., Sutphin, P. D., Raychaudhuri, S., Yu, S. Ct., Terris, D. J., & Giaccia, A. J. (2003). Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. CLINICAL CANCER RESEARCH, 9(1), 59-67.

Tumor hypoxia is important in radiotherapy, but how should we measure it?
Brown, J. M., & Le, Q. T. (2002). Tumor hypoxia is important in radiotherapy, but how should we measure it?. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 54(5), 1299-1301.

Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay
Terris, D. J., Ho, E. Y., Ibrahim, H. Z., Dorie, M. J., Kovacs, M. S., & Brown, J. M. (2002). Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 128(6), 698-702.

The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery
Murphy, M. J., Martin, D., Whyte, R., Hai, J., Ozhasoglu, C., & Le, Q. T. (2002). The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 53(2), 475-482.

Primary radiotherapy for localized orbital malt lymphoma
Le, Q. T., Eulau, S. M., George, T. I., Hildebrand, R., Warnke, R. A., & Hoppe, R. T. (2002). Primary radiotherapy for localized orbital malt lymphoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 52(3), 657-663.

Tirapazamine: Prototype for a novel class of therapeutic agents targeting tumor hypoxia
Gandara, D. R., Lara, P. N., Goldberg, Z., Le, Q. T., Mack, P. C., & Gumerlock, P. H. (2002). Tirapazamine: Prototype for a novel class of therapeutic agents targeting tumor hypoxia. SEMINARS IN ONCOLOGY, 29(1), 102-109.

Image-guided radiosurgery in the treatment of spinal metastases.
MURPHY, M. J., Chang, S., Gibbs, I., Le, Q. T., Martin, D., & Kim, D. (2001). Image-guided radiosurgery in the treatment of spinal metastases. Neurosurgical focus, 11(6).

Image-guided hypo-fractionated stereotactic radiosurgery to spinal lesions
Ryu, S. I., Chang, S. D., Kim, D. H., MURPHY, M. J., Le, Q. T., & Adler, J. R. (2001). Image-guided hypo-fractionated stereotactic radiosurgery to spinal lesions. NEUROSURGERY, 49(4), 838-846.

Treatment results and prognostic factors of advanced T3-4 laryngeal carcinoma: The University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience
Nguyen-Tan, P. F., Le, Q. T., Quivey, J. M., Singer, M., Terris, D. J., & Fu, K. K. (2001). Treatment results and prognostic factors of advanced T3-4 laryngeal carcinoma: The University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 50(5), 1172-1180.

Role of beam orientation optimization in intensity-modulated radiation therapy
Pugachev, A., Li, J. G., Boyer, A. L., Hancock, S. L., Le, Q. T., & Xing, L. (2001). Role of beam orientation optimization in intensity-modulated radiation therapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 50(2), 551-560.

Daily low-dose carboplatin as a radiation sensitizer for newly diagnosed malignant glioma
Peterson, K., Harsh, G., Fisher, P. G., Adler, J., & Le, Q. (2001). Daily low-dose carboplatin as a radiation sensitizer for newly diagnosed malignant glioma. JOURNAL OF NEURO-ONCOLOGY, 53(1), 27-32.

Treatment results of carcinoma in situ of the glottis - An analysis of 82 cases
Le, Q. T., Takamiya, R., Shu, H. K., Smitt, M., Singer, M., & Fu, K. K. (2000). Treatment results of carcinoma in situ of the glottis - An analysis of 82 cases. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 126(11), 1305-1312.

Pancreatic tumors show high levels of hypoxia
Koong, A. C., Mehta, V. K., Le, Q. T., Fisher, G. A., Terris, D. J., & Vierra, M. (2000). Pancreatic tumors show high levels of hypoxia. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 48(4), 919-922.

Head and neck cancer in cardiothoracic transplant recipients
Pollard, J. D., Hanasono, M. M., Mikulec, A. A., Le, Q. T., & Terris, D. J. (2000). Head and neck cancer in cardiothoracic transplant recipients. LARYNGOSCOPE, 110(8), 1257-1261.

Dosimetric effects of patient displacement and collimator and gantry angle misalignment on intensity modulated radiation therapy
Xing, L., Lin, Z. X., Donaldson, S. S., Le, Q. T., Tate, D., & Boyer, A. L. (2000). Dosimetric effects of patient displacement and collimator and gantry angle misalignment on intensity modulated radiation therapy. RADIOTHERAPY AND ONCOLOGY, 56(1), 97-108.

Candidate genes for the hypoxic tumor phenotype
Koong, A. C., Denko, N. C., Hudson, K. M., Schindler, C., Swiersz, L., & Giaccia, A. J. (2000). Candidate genes for the hypoxic tumor phenotype. CANCER RESEARCH, 60(4), 883-887.

Lymph node metastasis in maxillary sinus carcinoma
Le, Q. T., Fu, K. K., Kaplan, M. J., Terris, D. J., Fee, W. E., & Goffinet, D. R. (2000). Lymph node metastasis in maxillary sinus carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(3), 541-549.

Image-guided radiosurgery for the spine and pancreas.
Murphy, M. J., Adler, J. R., Bodduluri, M., Dooley, J., Forster, K., & Poen, J. (2000). Image-guided radiosurgery for the spine and pancreas. Computer aided surgery , 5(4), 278-288.

Estimation theory and model parameter selection for therapeutic treatment plan optimization
Xing, L., Li, J. G., Pugachev, A., Le, Q. T., & Boyer, A. L. (1999). Estimation theory and model parameter selection for therapeutic treatment plan optimization. MEDICAL PHYSICS, 26(11), 2348-2358.

Treatment of maxillary sinus carcinoma - A comparison of the 1997 and 1977 American Joint Committee on Cancer staging systems
Le, Q. T., Fu, K. K., Kaplan, M., Terris, D. J., Fee, W. E., & Goffinet, D. R. (1999). Treatment of maxillary sinus carcinoma - A comparison of the 1997 and 1977 American Joint Committee on Cancer staging systems. CANCER, 86(9), 1700-1711.

DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine.
Dorie, M. J., Kovacs, M. S., Gabalski, E. C., Adam, M., Le, Q. T., & Brown, J. M. (1999). DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine. Neoplasia , 1(5), 461-467.

Optimization of importance factors in inverse planning
Xing, L., Li, J. G., Donaldson, S., Le, Q. T., & Boyer, A. L. (1999). Optimization of importance factors in inverse planning. PHYSICS IN MEDICINE AND BIOLOGY, 44(10), 2525-2536.

Postoperative irradiation of minor salivary gland malignancies of the head and neck
Le, Q. T., Birdwell, S., Terris, D. J., Gabalski, E. C., Varghese, A., & Goffinet, D. R. (1999). Postoperative irradiation of minor salivary gland malignancies of the head and neck. RADIOTHERAPY AND ONCOLOGY, 52(2), 165-171.

Cell cycle proteins and the development of oral squamous cell carcinoma
Schoelch, M. L., Regezi, J. A., Dekker, N. P., Ng, I. Ol., McMillan, A., & Fu, K. K. (1999). Cell cycle proteins and the development of oral squamous cell carcinoma. ORAL ONCOLOGY, 35(3), 333-342.

Apoptosis-associated proteins and the development of oral squamous cell carcinoma
Schoelch, M. L., Le, Q. T., Silverman, S., McMillan, A., Dekker, N. P., & Regezi, J. A. (1999). Apoptosis-associated proteins and the development of oral squamous cell carcinoma. ORAL ONCOLOGY, 35(1), 77-85.

Post-operative irradiation of minor salivary gland malignancies of the head and neck.
Le QT, Birdwell S, Terris DJ, Gabalski EC, Varghese A, & Goffinet DR. (1999). Post-operative irradiation of minor salivary gland malignancies of the head and neck. Radiotherapy Oncology, 2(52).

A medical knowledge based system for the section of beam orientations in intensity modulated radiation therapy (IMRT).
Le QT, Xing L, Pugachev A, Li J, Donaldson S, & Boyer A. (1998). A medical knowledge based system for the section of beam orientations in intensity modulated radiation therapy (IMRT). Int J Radiat Oncol Biol Phys, 3S(45).

Soft-tissue sarcomas. In: Phillips TL, Leibel S, eds.
Le QT, Phillips TL, & Leibel S. (1998). Soft-tissue sarcomas. In: Phillips TL, Leibel S, eds. Textbook of Radiation Oncology, 1st Edition. Philadelphia: WB Saunders.

Spinal cord dose discrepancy in IMRT treated patients at Stanford revealed by Monte Carlo dose verification: clinical summary.
Le QT, Guerrero TM, Pawlicki T, Ma CM, Forster KM, & Goffinet DR. (1998). Spinal cord dose discrepancy in IMRT treated patients at Stanford revealed by Monte Carlo dose verification: clinical summary. Int J Radiat Oncol Biol Phys, 3S(45).

Influence of fraction size, total dose, and overall time on local control of T1-T2 glottic carcinoma
LE, Q. Tx., Fu, K. K., KROLL, S., Ryu, J. K., Quivey, J. M., & Phillips, T. L. (1997). Influence of fraction size, total dose, and overall time on local control of T1-T2 glottic carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 39(1), 115-126.

Adult medulloblastoma: An analysis of survival and prognostic factors
Le, Q. T., Weil, M. D., Wara, W. M., Lamborn, K. R., Prados, M. D., & Gutin, P. H. (1997). Adult medulloblastoma: An analysis of survival and prognostic factors. CANCER JOURNAL, 3(4), 238-245.

Prognostic factors in adult soft-tissue sarcomas of the head and neck
LE, Q. Tx., Fu, K. K., KROLL, S., Fitts, L., Massullo, V., & Phillips, T. L. (1997). Prognostic factors in adult soft-tissue sarcomas of the head and neck. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 37(5), 975-984.

PATTERN OF RECURRENCE OF MEDULLOBLASTOMA AFTER LOW-DOSE CRANIOSPINAL RADIOTHERAPY
Wara, W. M., LE, Q. Tx., Sneed, P. K., Larson, D. A., Prados, M. D., & Weil, M. D. (1994). PATTERN OF RECURRENCE OF MEDULLOBLASTOMA AFTER LOW-DOSE CRANIOSPINAL RADIOTHERAPY. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 30(3), 551-556.