Melanie Manning

Geneticist

Clinical Assistant Professor, Pathology Clinical Assistant Professor, Pediatrics - Medical Genetics

Professional Education

Board Certification: Pediatrics, American Board of Pediatrics (2000)

Medical Education: Eastern VA Medical School (1997) VA

Residency: Stanford University School of Medicine (2002) CA

Residency: Maricopa Medical Center (2000) AZ

Fellowship: Stanford University School of Medicine (2003) CA

Board Certification: Clinical Cytogenetics, American Board of Medical Genetics (2005)

Board Certification: Clinical Genetics, American Board of Medical Genetics (2002)

Internship: Maricopa Medical Center (1998) AZ

Maternal factors predicting cognitive and behavioral characteristics of children with fetal alcohol spectrum disorders.
May, P. A., Tabachnick, B. G., Gossage, J. P., Kalberg, W. O., Marais, A.-S., & Adnams, C. M. (2013). Maternal factors predicting cognitive and behavioral characteristics of children with fetal alcohol spectrum disorders. Journal of developmental and behavioral pediatrics , 34(5), 314-325.

Axial spondylometaphyseal dysplasia with retinitis pigmentosa-a clinical report and diagnostic clues.
Reinstein, E., Okenfuss, E. B., Wadhawan, I., Wilnai, Y., Manning, M., & Lachman, R. S. (2013). Axial spondylometaphyseal dysplasia with retinitis pigmentosa-a clinical report and diagnostic clues. Journal of applied genetics, 54(2), 231-234.

Approaching the prevalence of the full spectrum of fetal alcohol spectrum disorders in a South african population-based study.
May, P. A., Blankenship, J., Marais, A.-S., Gossage, J. P., Kalberg, W. O., & Seedat, S. (2013). Approaching the prevalence of the full spectrum of fetal alcohol spectrum disorders in a South african population-based study. Alcoholism, clinical and experimental research, 37(5), 818-830.

Marked variability in the radiographic features of cartilage-hair hypoplasia: Case report and review of the literature
Kwan, A., Manning, M. A., Zollars, L. K., & Hoyme, H. E. (2012). Marked variability in the radiographic features of cartilage-hair hypoplasia: Case report and review of the literature. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 158A(11), 2911-2916.

Report of Two Patients and Further Characterization of Interstitial 9p13 Deletion-A Rare But Recurrent Microdeletion Syndrome?
Niemi, A.-K., Kwan, A., Hudgins, L., Cherry, A. M., & Manning, M. A. (2012). Report of Two Patients and Further Characterization of Interstitial 9p13 Deletion-A Rare But Recurrent Microdeletion Syndrome?. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 158A(9), 2328-2335.

Maternal risk factors predicting child physical characteristics and dysmorphology in fetal alcohol syndrome and partial fetal alcohol syndrome
May, P. A., Tabachnick, B. G., Gossage, J. P., Kalberg, W. O., Marais, A.-S., & Hoyme, H. E. (2011). Maternal risk factors predicting child physical characteristics and dysmorphology in fetal alcohol syndrome and partial fetal alcohol syndrome. DRUG AND ALCOHOL DEPENDENCE, 119(1-2), 18-27.

Ectopia Lentis as the Presenting and Primary Feature in Marfan Syndrome
Zadeh, N., Bernstein, J. A., Niemi, A. K., Dugan, S., Kwan, A., & Manning, M. A. (2011). Ectopia Lentis as the Presenting and Primary Feature in Marfan Syndrome. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 155A(11), 2661-2668.

Chromosome 22q11.2 Deletion Syndrome in African-American Patients: A Diagnostic Challenge
Veerapandiyan, A., Abdul-Rahman, O. A., Adam, M. P., Lyons, M. J., Manning, M., & Shashi, V. (2011). Chromosome 22q11.2 Deletion Syndrome in African-American Patients: A Diagnostic Challenge. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 155A(9), 2186-2195.

Prevalence of Children with Severe Fetal Alcohol Spectrum Disorders in Communities Near Rome, Italy: New Estimated Rates Are Higher than Previous Estimates
May, P. A., Fiorentino, D., Coriale, G., Kalberg, W. O., Hoyme, H. E., & Ceccanti, M. (2011). Prevalence of Children with Severe Fetal Alcohol Spectrum Disorders in Communities Near Rome, Italy: New Estimated Rates Are Higher than Previous Estimates. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 8(6), 2331-2351.

Fetal Alcohol Spectrum Disorders: Extending the Range of Structural Defects
Jones, K. L., Hoyme, H. E., Robinson, L. K., del Campo, M., Manning, M. A., & Chambers, C. D. (2010). Fetal Alcohol Spectrum Disorders: Extending the Range of Structural Defects. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 152A(11), 2731-2735.

Array-based technology and recommendations for utilization in medical genetics practice for detection of chromosomal abnormalities
Manning, M., & Hudgins, L. (2010). Array-based technology and recommendations for utilization in medical genetics practice for detection of chromosomal abnormalities. GENETICS IN MEDICINE, 12(11), 742-745.

Population Differences in Dysmorphic Features Among Children With Fetal Alcohol Spectrum Disorders
May, P. A., Gossage, J. P., Smith, M., Tabachnick, B. G., Robinson, L. K., & Hoyme, H. E. (2010). Population Differences in Dysmorphic Features Among Children With Fetal Alcohol Spectrum Disorders. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 31(4), 304-316.

Developmental Pathogenesis of Short Palpebral Fissure Length in Children with Fetal Alcohol Syndrome
Jones, K. L., Hoyme, H. E., Robinson, L. K., del Campo, M., Manning, M. A., & Chambers, C. D. (2009). Developmental Pathogenesis of Short Palpebral Fissure Length in Children with Fetal Alcohol Syndrome. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 85(8), 695-699.

PREVALENCE AND EPIDEMIOLOGIC CHARACTERISTICS OF FASD FROM VARIOUS RESEARCH METHODS WITH AN EMPHASIS ON RECENT IN-SCHOOL STUDIES
May, P. A., Gossage, J. P., Kalberg, W. O., Robinson, L. K., Buckley, D., & Hoyme, H. E. (2009). PREVALENCE AND EPIDEMIOLOGIC CHARACTERISTICS OF FASD FROM VARIOUS RESEARCH METHODS WITH AN EMPHASIS ON RECENT IN-SCHOOL STUDIES. DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS, 15(3), 176-192.

Clinical and molecular delineation of the 17q21.31 microdeletion syndrome
Koolen, D. A., Sharp, A. J., Hurst, J. A., Firth, H. V., Knight, S. Jl., & de Vries, B. Ba. (2008). Clinical and molecular delineation of the 17q21.31 microdeletion syndrome. JOURNAL OF MEDICAL GENETICS, 45(11), 710-720.

Sclerocornea associated with the chromosome 22q11.2 deletion syndrome.
Binenbaum, G., McDonald-McGinn, D. M., Zackai, E. H., Walker, B. M., Coleman, K., & Forbes, B. J. (2008). Sclerocornea associated with the chromosome 22q11.2 deletion syndrome. American journal of medical genetics. Part A, 146(7), 904-909.

22q13.3 deletion syndrome: A recognizable malformation syndrome associated with marked speech and language delay
Cusmano-Ozog, K., Manning, M. A., & Hoyme, H. E. (2007). 22q13.3 deletion syndrome: A recognizable malformation syndrome associated with marked speech and language delay. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS, 145C(4), 393-398.

Use of array-based technology in the practice of medical genetics
Manning, M., & Hudgins, L. (2007). Use of array-based technology in the practice of medical genetics. GENETICS IN MEDICINE, 9(9), 650-653.

Whole-genome array-CGH identifies novel contiguous gene deletions and duplications associated with developmental delay, mental retardation, and dysmorphic features
Aradhya, S., Manning, M. A., Splendore, A., & Cherry, A. M. (2007). Whole-genome array-CGH identifies novel contiguous gene deletions and duplications associated with developmental delay, mental retardation, and dysmorphic features. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 143A(13), 1431-1441.

Fetal alcohol spectrum disorders: A practical clinical approach to diagnosis
Manning, M. A., & Hoyme, H. E. (2007). Fetal alcohol spectrum disorders: A practical clinical approach to diagnosis. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 31(2), 230-238.

Nablus mask-like facial syndrome is caused by a microdeletion of 8q detected by array-based comparative genomic hybridization.
Shieh, J. Tc., Aradhya, S., Novelli, A., Manning, M. A., Cherry, A. M., & Hoyme, H. E. (2006). Nablus mask-like facial syndrome is caused by a microdeletion of 8q detected by array-based comparative genomic hybridization. American journal of medical genetics. Part A, 140(12), 1267-1273.

A report of three patients with an interstitial deletion of chromosome 15q24
Cushman, L. J., Torres-Martinez, W., Cherry, A. M., Manning, M. A., Abdul-Rahman, O., & Vance, G. H. (2005). A report of three patients with an interstitial deletion of chromosome 15q24. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 137A(1), 65-71.

Terminal 22q deletion syndrome: A newly recognized cause of speech and language disability in the autism spectrum
Manning, M. A., Cassidy, S. B., Clericuzio, C., Cherry, A. M., Schwartz, S., & Hoyme, H. E. (2004). Terminal 22q deletion syndrome: A newly recognized cause of speech and language disability in the autism spectrum. PEDIATRICS, 114(2), 451-457.

Neu-Laxova syndrome: Detailed prenatal diagnostic and post-mortem findings and literature review
Manning, M. A., Cunniff, C. M., Colby, C. E., El-Sayed, Y. Y., & Hoyme, H. E. (2004). Neu-Laxova syndrome: Detailed prenatal diagnostic and post-mortem findings and literature review. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 125A(3), 240-249.

Head imaging abnormalities in dihydropyrimidine dehydrogenase deficiency
Enns, G. M., Barkovich, A. J., van Kuilenburg, A. Bp., Manning, M., Sanger, T., & Van Gennip, A. H. (2004). Head imaging abnormalities in dihydropyrimidine dehydrogenase deficiency. JOURNAL OF INHERITED METABOLIC DISEASE, 27(4), 513-522.

Methotrexate/misoprostol embryopathy: Report of four cases resulting from failed medical abortion
Adam, M. P., Manning, M. A., Beck, A. E., Kwan, A., Enns, G. M., & Hoyme, H. E. (2003). Methotrexate/misoprostol embryopathy: Report of four cases resulting from failed medical abortion. AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 123A(1), 72-78.

Diagnosis and management of the adolescent boy with Klinefelter syndrome.
Manning, M. A., & Hoyme, H. E. (2002). Diagnosis and management of the adolescent boy with Klinefelter syndrome. Adolescent medicine (Philadelphia, Pa.), 13(2), 367-?.

Intracranial hemorrhage in infants and children with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome)
Morgan, T., McDonald, J., Anderson, C., Ismail, M., Miller, F., & Manning, M. (2002). Intracranial hemorrhage in infants and children with hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome). PEDIATRICS, 109(1).