Michelle Monje

Neuro-oncologist

Assistant Professor of Neurology and, by courtesy, of Neurosurgery, of Pediatrics and of Pathology

Brain Tumor Center

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-6469
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Professional Education

Subspecialty Board Certification, United Council for Neurological Subspecialties, Neuro-Oncology (2013)

Fellowship: Stanford University - Dept of Neurology (06/30/2010) CA

Board Certification: Neurology, American Board of Psychiatry and Neurology (2008)

Residency: Brigham and Women's Hospital Harvard Medical School (06/30/2008) MA

Residency: Massachusetts General Hospital (06/30/2008) MA

Internship: Stanford University (06/30/2005) CA

Medical Education: Stanford University (06/13/2004) CA

PhD, Stanford University, Neuroscience (2004)

MD, Stanford University (2004)

Honors & Awards

New Faculty Physician Scientist Translational Research Award, California Institute of Regenerative Medicine (CIRM) (2013 - 2018)

Basic Science IV Award, California Institute of Regenerative Medicine (CIRM) (2012 - 2015)

‘A’ Award, Alex’s Lemonade Stand Foundation (2012-2015)

Peter A. Steck Memorial Award, Pediatric Brain Tumor Foundation (2011)

K08 Mentored Clinical Scientist Career Development Award, National Institutes of Neurological Disorders and Stroke (2010 - 2015)

Young Investigator Award, Hagerty Foundation for Glioma Research (2006)

Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
Gibson, E. M., Purger, D., Mount, C. W., Goldstein, A. K., Lin, G. L., & Monje, M. (2014). Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. Science , 344(6183), 1252304-?.

Subventricular spread of diffuse intrinsic pontine glioma.
Caretti, V., Bugiani, M., Freret, M., Schellen, P., Jansen, M., & Monje, M. (2014). Subventricular spread of diffuse intrinsic pontine glioma. Acta neuropathologica.

Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma
Monje, M., Mitra, S. S., Freret, M. E., Raveh, T. B., Kim, J., & Beachy, P. A. (2011). Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(11), 4453-4458.

Impaired human hippocampal neurogenesis after treatment for central nervous system
Monje, M. L., Vogel, H., Masek, M., Ligon, K. L., Fisher, P. G., & Palmer, T. D. (2007). Impaired human hippocampal neurogenesis after treatment for central nervous system. ANNALS OF NEUROLOGY, 62(5), 515-520.

Inflammatory blockade restores adult hippocampal neurogenesis
Monje, M. L., Toda, H., & Palmer, T. D. (2003). Inflammatory blockade restores adult hippocampal neurogenesis. SCIENCE, 302(5651), 1760-1765.

Irradiation induces neural precursor-cell dysfunction
Monje, M. L., Mizumatsu, S., Fike, J. R., & Palmer, T. D. (2002). Irradiation induces neural precursor-cell dysfunction. NATURE MEDICINE, 8(9), 955-962.

Human pontine glioma cells can induce murine tumors.
Caretti, V., Sewing, A. Cp., Lagerweij, T., Schellen, P., Bugiani, M., & Wurdinger, T. (2014). Human pontine glioma cells can induce murine tumors. Acta neuropathologica, 127(6), 897-909.

Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma.
Lober, R. M., Cho, Y.-J., Tang, Y., Barnes, P. D., Edwards, M. S., & Yeom, K. W. (2014). Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma. Journal of neuro-oncology, 117(1), 175-182.

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.
Taylor, K. R., Mackay, A., Truffaux, N., Butterfield, Y. S., Morozova, O., & Grill, J. (2014). Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. Nature genetics.

Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas.
Bender, S., Tang, Y., Lindroth, A. M., Hovestadt, V., Jones, D. Tw., & Pfister, S. M. (2013). Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas. Cancer cell, 24(5), 660-672.

Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia
Monje, M., Thomason, M. E., Rigolo, L., Wang, Y., Waber, D. P., & Golby, A. J. (2013). Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia. PEDIATRIC BLOOD & CANCER, 60(2), 293-300.

Effect of cancer therapy on neural stem cells: implications for cognitive function
Gibson, E., & Monje, M. (2012). Effect of cancer therapy on neural stem cells: implications for cognitive function. CURRENT OPINION IN ONCOLOGY, 24(6), 672-678.

Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis
Monje, M., & Dietrich, J. (2012). Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis. BEHAVIOURAL BRAIN RESEARCH, 227(2), 376-379.

Hedgehogs, Flies, Wnts and MYCs: The Time Has Come for Many Things in Medulloblastoma
Monje, M., Beachy, P. A., & Fisher, P. G. (2011). Hedgehogs, Flies, Wnts and MYCs: The Time Has Come for Many Things in Medulloblastoma. JOURNAL OF CLINICAL ONCOLOGY, 29(11), 1395-1398.

Neurological complications following treatment of children with brain tumors.
Monje, M., & Fisher, P. G. (2011). Neurological complications following treatment of children with brain tumors. Journal of pediatric rehabilitation medicine, 4(1), 31-36.

Clinical Patterns and Biological Correlates of Cognitive Dysfunction Associated with Cancer Therapy
Dietrich, J., Monje, M., Wefel, J., & Meyers, C. (2008). Clinical Patterns and Biological Correlates of Cognitive Dysfunction Associated with Cancer Therapy. ONCOLOGIST, 13(12), 1285-1295.

CRANIAL RADIATION THERAPY AND DAMAGE TO HIPPOCAMPAL NEUROGENESIS
Monje, M. (2008). CRANIAL RADIATION THERAPY AND DAMAGE TO HIPPOCAMPAL NEUROGENESIS. DEVELOPMENTAL DISABILITIES RESEARCH REVIEWS, 14(3), 238-242.

Excitation-neurogenesis coupling in adult neural stem/progenitor cells
Deisseroth, K., Singla, S., Toda, H., Monje, M., Palmer, T. D., & Malenka, R. C. (2004). Excitation-neurogenesis coupling in adult neural stem/progenitor cells. NEURON, 42(4), 535-552.

Radiation injury and neurogenesis
Monje, M. L., & Palmer, T. (2003). Radiation injury and neurogenesis. CURRENT OPINION IN NEUROLOGY, 16(2), 129-134.