Jayakar V. Nayak, MD, PhD

Otolaryngologist, Surgical oncologist, Head and neck surgeon, Head and neck surgical oncologist

Assistant Professor of Otolaryngology - Head & Neck Surgery at the Stanford University Medical Center

Head and Neck Cancer Program

  • 900 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
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Sinus Center

  • 801 Welch Road
  • Stanford, CA 94305
  • Phone: 650-723-5281
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Professional Education

Residency: University of Pittsburgh Medical Center (2008) PA

Internship: University of Pittsburgh Medical Center (2004) PA

Fellowship: University of Pennsylvania (2009) PA

M.D., Ph.D., University of Pittsburgh School of Medicine, MD - General Medicine PhD - Immunology (2003)

Medical Education: University of Pittsburgh School of Medicine (2003) PA

B.A., University of Pennsylvania, Neuroscience (1992)

Honors & Awards

Career Development Award - Basal cells in maintenance and regeneration of the nasal epithelium, Triological Society of the American Academy of Otolaryngology-Head and Neck Surgery (2012)

Human Mucosal Immune Responses to Influenza Virus: a Systems Biology Approach, NIH/Human Immunology Project Consortium (HIPC) (2012)

Immune Responses to Influenza Virus in Single Human Nasal Epithelial Cells, NIH/Cooperative Centers for Translational Research on Human Immunology and Biodefense (CCHI) (2012)

2D and 3D Electron Microscopy Ultrastructure of Murine Nasal Cavity, Stanford Beckman Center Technology Innovation MiniGrant program (2012)

Influenza virus tropism for human nasal epithelial cells of the upper airway, Marion Avery Family Grant (2012)

CORE Schering Plough Resident Research Award from the American Academy of Otolaryngology, University of Pittsburgh (2005)

Gold Foundation “Little Apple” Medical Student Teaching Award Finalist, University of Pittsburgh (2004)

Bernhard A. Goldman Prize in Dermatology, University of Pittsburgh (2003)

M.D./Ph.D. Transfer Admission & Full Scholarship Award, University of Pittsburgh (1997)

American Heart Association Medical Student Research Fellowship, U Californioa, San Diego (1996)

Howard Hughes Medical Institute Medical Student Research Fellowship, U California, San Diego (1995)

Stanley J. Sarnoff Endowment Medical Student Research Fellowship, Salk Institute, La Jolla, CA (1994)

Baccalaureate with Honors, University of Pennsylvania (1992)

Co-Valedictorian, Woodbridge High School, New Jersey (1988)

Long-term Sinonasal Outcomes of Aspirin Desensitization in Aspirin Exacerbated Respiratory Disease
Cho, K.-S., Soudry, E., Psaltis, A. J., Nadeau, K. C., McGhee, S. A., & Hwang, P. H. (2014). Long-term Sinonasal Outcomes of Aspirin Desensitization in Aspirin Exacerbated Respiratory Disease. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 151(4), 575-581.

Anatomic relationship of nasolacrimal duct and major lateral wall landmarks: cadaveric study with surgical implications
Ali, M. J., Nayak, J. V., Vaezeafshar, R., Li, G., & Psaltis, A. J. (2014). Anatomic relationship of nasolacrimal duct and major lateral wall landmarks: cadaveric study with surgical implications. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 4(8), 684-688.

Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission
Soudry, E., Mohabir, P. K., Miglani, A., Chen, J., Nayak, J. V., & Hwang, P. H. (2014). Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 4(5), 416-421.

Endoscopic Reconstruction of Surgically Created Skull Base Defects A Systematic Review
Soudry, E., Turner, J. H., Nayak, J. V., & Hwang, P. H. (2014). Endoscopic Reconstruction of Surgically Created Skull Base Defects A Systematic Review. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 150(5), 730-738.

Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission.
Soudry, E., Mohabir, P. K., Miglani, A., Chen, J., Nayak, J. V., & Hwang, P. H. (2014). Outpatient endoscopic sinus surgery in cystic fibrosis patients: predictive factors for admission. International forum of allergy & rhinology, 4(5), 416-421.

Experience with intraoperative navigation and imaging during endoscopic transnasal spinal approaches to the foramen magnum and odontoid.
Choudhri, O., Mindea, S. A., Feroze, A., Soudry, E., Chang, S. D., & Nayak, J. V. (2014). Experience with intraoperative navigation and imaging during endoscopic transnasal spinal approaches to the foramen magnum and odontoid. Neurosurgical focus, 36(3), E4-?.

Human ethmoid sinus mucosa: a promising novel tissue source of mesenchymal progenitor cells
Cho, K.-S., Park, H.-Y., Roh, H.-J., Bravo, D. T., Hwang, P. H., & Nayak, J. V. (2014). Human ethmoid sinus mucosa: a promising novel tissue source of mesenchymal progenitor cells. STEM CELL RESEARCH & THERAPY, 5.

Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients.
Edward, J. A., Sanyal, M., Ramakrishnan, V. R., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients. International forum of allergy & rhinology, 3(11), 866-876.

Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients
Edward, J. A., Sanyal, M., Ramakrishnan, V. R., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Systemic prednisone administration selectively alters granulocyte subsets in nasal polyps from aspirin-exacerbated respiratory disease and chronic rhinosinusitis patients. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 3(11), 866-876.

Characterization of human upper airway epithelial progenitors.
Bravo, D. T., Soudry, E., Edward, J. A., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Characterization of human upper airway epithelial progenitors. International forum of allergy & rhinology, 3(10), 841-847.

Characterization of human upper airway epithelial progenitors
Bravo, D. T., Soudry, E., Edward, J. A., Le, W., Nguyen, A. L., & Nayak, J. V. (2013). Characterization of human upper airway epithelial progenitors. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 3(10), 841-847.

Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis
Cho, D.-Y., Nayak, J. V., Bravo, D. T., Le, W., Nguyen, A., & Fischer, H. (2013). Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 3(5), 376-383.

Survival Outcomes in Acute Invasive Fungal Sinusitis: A Systematic Review and Quantitative Synthesis of Published Evidence
Turner, J. H., Soudry, E., Nayak, J. V., & Hwang, P. H. (2013). Survival Outcomes in Acute Invasive Fungal Sinusitis: A Systematic Review and Quantitative Synthesis of Published Evidence. LARYNGOSCOPE, 123(5), 1112-1118.

Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.
Cho, D.-Y., Nayak, J. V., Bravo, D. T., Le, W., Nguyen, A., & Fischer, H. (2013). Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis. International forum of allergy & rhinology, 3(5), 376-383.

Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis
Rujanavej, V., Soudry, E., Banaei, N., Baron, E. J., Hwang, P. H., & Nayak, J. V. (2013). Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 27(2), 134-137.

Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis.
Rujanavej, V., Soudry, E., Banaei, N., Baron, E. J., Hwang, P. H., & Nayak, J. V. (2013). Trends in incidence and susceptibility among methicillin-resistant Staphylococcus aureus isolated from intranasal cultures associated with rhinosinusitis. American journal of rhinology & allergy, 27(2), 134-137.

Low-frequency pulsed ultrasound in the nasal cavity and paranasal sinuses: a feasibility and distribution study
Patel, Z. M., Hwang, P. H., Chernomorsky, A., Bravo, D. T., Nguyen, B. L., & Nayak, J. V. (2012). Low-frequency pulsed ultrasound in the nasal cavity and paranasal sinuses: a feasibility and distribution study. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(4), 303-308.

Nationwide incidence of major complications in endoscopic sinus surgery
Ramakrishnan, V. R., Kingdom, T. T., Nayak, J. V., Hwang, P. H., & Orlandi, R. R. (2012). Nationwide incidence of major complications in endoscopic sinus surgery. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(1), 34-39.

Sinonasal seromucinous hamartomas: Clinical features and diagnostic dilemma
Figures, M. R., Nayak, J. V., Gable, C., & Chiu, A. G. (2010). Sinonasal seromucinous hamartomas: Clinical features and diagnostic dilemma. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 143(1), 165-166.

Assessing the risk of irrigation bottle and fluid contamination after endoscopic sinus surgery
Lee, J. M., Nayak, J. V., Doghramji, L. L., Welch, K. C., & Chiu, A. G. (2010). Assessing the risk of irrigation bottle and fluid contamination after endoscopic sinus surgery. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 24(3), 197-199.

Biofilms in chronic rhinosinusitis: A review
Cohen, M., Kofonow, J., Nayak, J. V., Palmer, J. N., Chiu, A. G., & Cohen, N. A. (2009). Biofilms in chronic rhinosinusitis: A review. AMERICAN JOURNAL OF RHINOLOGY & ALLERGY, 23(3), 255-260.

Head and neck epithelioid sarcoma in a child: Diagnostic dilemma and anterolateral thigh free flap reconstruction
Nayak, J. V., Teot, L. A., Vyas, Y., Snyderman, C. H., Toh, E. H., & Deleyiannis, F. Wb. (2008). Head and neck epithelioid sarcoma in a child: Diagnostic dilemma and anterolateral thigh free flap reconstruction. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 72(5), 719-724.

Head and Neck Cancer Immunotherapy: Clinical Evaluation
Leibowitz, M. S., Nayak, J. V., & Ferris, R. L. (2008). Head and Neck Cancer Immunotherapy: Clinical Evaluation. CURRENT ONCOLOGY REPORTS, 10(2), 162-169.

Deferring planned neck dissection following chemoradiation for stage IV head and neck cancer: The utility of PET-CT
Nayak, J. V., Walvekar, R. R., Andrade, R. S., Daamen, N., Lai, S. Y., & Branstetter, B. F. (2007). Deferring planned neck dissection following chemoradiation for stage IV head and neck cancer: The utility of PET-CT. LARYNGOSCOPE, 117(12), 2129-2134.

Experience with the expanded endonasal approach for resection of the odontoid process in rheumatoid disease
Nayak, J. V., Gardner, P. A., Vescan, A. D., Carrau, R. L., Kassam, A. B., & Snyderman, C. H. (2007). Experience with the expanded endonasal approach for resection of the odontoid process in rheumatoid disease. AMERICAN JOURNAL OF RHINOLOGY, 21(5), 601-606.

Phagocytosis induces lysosome remodeling and regulated presentation of particulate antigens by activated dendritic cells
Nayak, J. V., Hokey, D. A., Larregina, A., He, Y., Salter, R. D., & Falo, L. D. (2006). Phagocytosis induces lysosome remodeling and regulated presentation of particulate antigens by activated dendritic cells. JOURNAL OF IMMUNOLOGY, 177(12), 8493-8503.

Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL
Lopez-Albaitero, A., Nayak, J. V., Ogino, T., Machandia, A., Gooding, W., & Ferris, R. L. (2006). Role of antigen-processing machinery in the in vitro resistance of squamous cell carcinoma of the head and neck cells to recognition by CTL. JOURNAL OF IMMUNOLOGY, 176(6), 3402-3409.

Current use of F-18-fluorodeoxyglucose positron emission tomography and combined positron emission tomography and computed tomography in squamous cell carcinoma of the head and neck
Zimmer, L. A., Branstetter, B. F., Nayak, J. V., & Johnson, J. T. (2005). Current use of F-18-fluorodeoxyglucose positron emission tomography and combined positron emission tomography and computed tomography in squamous cell carcinoma of the head and neck. LARYNGOSCOPE, 115(11), 2029-2034.

Diagnostic utility of positron emission tomography-computed tomography for predicting malignancy in cystic neck masses in adults
Ferris, R. L., Branstetter, B. F., & Nayak, J. V. (2005). Diagnostic utility of positron emission tomography-computed tomography for predicting malignancy in cystic neck masses in adults. LARYNGOSCOPE, 115(11), 1979-1982.

Sensitization with xenogeneic tissues alters the heavy chain repertoire of human anti-Ga1 alpha 1-3Ga1 antibodies
Yu, P. B., Parker, W., Nayak, J. V., & Platt, J. L. (2005). Sensitization with xenogeneic tissues alters the heavy chain repertoire of human anti-Ga1 alpha 1-3Ga1 antibodies. TRANSPLANTATION, 80(1), 102-109.

Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses
DiLeo, J., Banerjee, R., Whitmore, M., Nayak, J. V., Falo, L. D., & Huang, L. (2003). Lipid-protamine-DNA-mediated antigen delivery to antigen-presenting cells results in enhanced anti-tumor immune responses. MOLECULAR THERAPY, 7(5), 640-648.

Myoepithelial neoplasia of the submandibular gland - Case report and therapeutic considerations
Nayak, J. V., Molina, J. T., Smith, J. C., Branstetter, B. F., Hunt, J. L., & Snyderman, C. H. (2003). Myoepithelial neoplasia of the submandibular gland - Case report and therapeutic considerations. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 129(3), 359-362.

Primary lymphoma of the larynx: New diagnostic and therapeutic approaches
Nayak, J. V., Cook, J. R., Molina, J. T., Branch, M. P., Branstetter, B. F., & Myers, E. N. (2003). Primary lymphoma of the larynx: New diagnostic and therapeutic approaches. ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 65(6), 321-326.

Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo
He, Y. K., Pimenov, A. A., Nayak, J. V., Plowey, J., Falo, L. D., & Huang, L. (2000). Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo. HUMAN GENE THERAPY, 11(4), 547-554.

The dual phases of the response to neonatal exposure to a V-H family-restricted staphylococcal B cell superantigen
Silverman, G. J., Nayak, J. V., Warnatz, K., Hajjar, F. F., Cary, S., & Curtiss, V. E. (1998). The dual phases of the response to neonatal exposure to a V-H family-restricted staphylococcal B cell superantigen. JOURNAL OF IMMUNOLOGY, 161(10), 5720-5732.

In vivo consequences of B cell superantigen immunization
Silverman, G. J., Nayak, J. V., Wagenknecht, R., & Warnatz, K. (1997). In vivo consequences of B cell superantigen immunization. B LYMPHOCYTES AND AUTOIMMUNITY, 815, 105-110.

B-cell superantigens: molecular and cellular implications.
Silverman, G. J., Nayak, J. V., & La Cava, A. (1997). B-cell superantigens: molecular and cellular implications. International reviews of immunology, 14(4), 259-290.