Lawrence Recht, MD

Neuro-oncologist

Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center

Brain Tumor Center

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-6469
Learn More About the Clinic Getting Here Make An Appointment

Neurogenetic Oncology Program

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-6469
Learn More About the Clinic Getting Here Make An Appointment

Brain Tumor Center at the Advanced Medicine Center, Clinic D

  • 875 Blake Wilbur Drive
  • Palo Alto, CA 94304
  • Phone: 650-498-6000
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Fellowship: Memorial Sloan-Kettering Cancer Center (1984) NY

Residency: University of Minnesota School of Medicine (1979) MN

Board Certification: Neurology, American Board of Psychiatry and Neurology (1983)

Residency: New York Presbyterian Hospital (1982) NY

Internship: University of Minnesota School of Medicine (1978) MN

Medical Education: Columbia Presbyterian Medical Center (1977) NY

M.D., Columbia College of P&S, Medicine (1977)

Central Nervous System Cancers Clinical Practice Guidelines in Oncology
Nabors, L. B., Ammirati, M., Bierman, P. J., Brem, H., Butowski, N., & Ho, M. (2013). Central Nervous System Cancers Clinical Practice Guidelines in Oncology. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 11(9), 1114-1151.

Simultaneous perfusion and permeability measurements using combined spin- and gradient-echo MRI
Schmiedeskamp, H., Andre, J. B., Straka, M., Christen, T., Nagpal, S., & Bammer, R. (2013). Simultaneous perfusion and permeability measurements using combined spin- and gradient-echo MRI. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 33(5), 732-743.

ETIRINOTECAN PEGOL DNA Topoisomerase 1 Inhibitor Oncolytic
Nagpal, S., & Recht, L. D. (2013). ETIRINOTECAN PEGOL DNA Topoisomerase 1 Inhibitor Oncolytic. DRUGS OF THE FUTURE, 38(4), 227-233.

Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized (13)C magnetic resonance spectroscopic imaging.
Park, J. M., Recht, L. D., Josan, S., Merchant, M., Jang, T., & Mayer, D. (2013). Metabolic response of glioma to dichloroacetate measured in vivo by hyperpolarized (13)C magnetic resonance spectroscopic imaging. Neuro-oncology, 15(4), 433-441.

Steroid-sparing effect of corticorelin acetate in peritumoral cerebral edema is associated with improvement in steroid-induced myopathy.
Recht, L., Mechtler, L. L., Wong, E. T., O'Connor, P. C., & Rodda, B. E. (2013). Steroid-sparing effect of corticorelin acetate in peritumoral cerebral edema is associated with improvement in steroid-induced myopathy. Journal of clinical oncology , 31(9), 1182-1187.

Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage.
Yamaguchi, Y., Shao, Z., Sharif, S., Du, X.-Y., Myles, T., & Leung, L. Lk. (2013). Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage. journal of biological chemistry, 288(5), 3097-3111.

Advances in the management of glioblastoma: the role of temozolomide and MGMT testing.
Thomas, R. P., Recht, L., & Nagpal, S. (2013). Advances in the management of glioblastoma: the role of temozolomide and MGMT testing. Clinical pharmacology : advances and applications, 5, 1-9.

Alterations in Cerebrospinal Fluid Proteins in a Presymptomatic Primary Glioma Model
Whitin, J. C., Jang, T., Merchant, M., Yu, T. Ts., Lau, K., & Recht, L. (2012). Alterations in Cerebrospinal Fluid Proteins in a Presymptomatic Primary Glioma Model. PLOS ONE, 7(11).

Metabolite kinetics in C6 rat glioma model using magnetic resonance spectroscopic imaging of hyperpolarized [1-13C]pyruvate
Park, J. M., Josan, S., Jang, T., Merchant, M., Yen, Y.-F., & Mayer, D. (2012). Metabolite kinetics in C6 rat glioma model using magnetic resonance spectroscopic imaging of hyperpolarized [1-13C]pyruvate. MAGNETIC RESONANCE IN MEDICINE, 68(6), 1886-1893.

Preliminary use of differential scanning calorimetry of cerebrospinal fluid for the diagnosis of glioblastoma multiforme
Chagovetz, A. A., Jensen, R. L., Recht, L., Glantz, M., & Chagovetz, A. M. (2011). Preliminary use of differential scanning calorimetry of cerebrospinal fluid for the diagnosis of glioblastoma multiforme. JOURNAL OF NEURO-ONCOLOGY, 105(3), 499-506.

Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma
Zhao, L., Yamaguchi, Y., Sharif, S., Du, X.-Y., Song, J. J., & Leung, L. Lk. (2011). Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(45), 39520-39527.

Treatment and Prophylaxis of Hematologic Malignancy in the Central Nervous System
Nagpal, S., & Recht, L. (2011). Treatment and Prophylaxis of Hematologic Malignancy in the Central Nervous System. CURRENT TREATMENT OPTIONS IN NEUROLOGY, 13(4), 400-412.

5 '-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat
Jang, T., Calaoagan, J. M., Kwon, E., Samuelsson, S., Recht, L., & Laderoute, K. R. (2011). 5 '-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat. INTERNATIONAL JOURNAL OF CANCER, 128(9), 2230-2239.

Central Nervous System Cancers
Brem, S. S., Bierman, P. J., Brem, H., Butowski, N., Chamberlain, M. C., & Wen, P. Y. (2011). Central Nervous System Cancers. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 9(4), 352-400.

Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy
Barretto, R. Pj., Ko, T. H., Jung, J. C., Wang, T. J., Capps, G., & Schnitzer, M. J. (2011). Time-lapse imaging of disease progression in deep brain areas using fluorescence microendoscopy. NATURE MEDICINE, 17(2), 223-U120.

Bevacizumab improves quality of life in patients with recurrent glioblastoma.
Nagpal, S., Harsh, G., & Recht, L. (2011). Bevacizumab improves quality of life in patients with recurrent glioblastoma. Chemotherapy research and practice, 2011, 602812-?.

VERUBULIN HYDROCHLORIDE Apoptosis Inducer Vascular Disrupting Agent Oncolytic
Thomas, P., & Recht, L. (2010). VERUBULIN HYDROCHLORIDE Apoptosis Inducer Vascular Disrupting Agent Oncolytic. DRUGS OF THE FUTURE, 35(12), 993-997.

Treatment and Prevention of Secondary CNS Lymphoma
Nagpal, S., Glantz, M. J., & Recht, L. (2010). Treatment and Prevention of Secondary CNS Lymphoma. SEMINARS IN NEUROLOGY, 30(3), 263-272.

Murine Embryonic Stem Cell-Derived Pyramidal Neurons Integrate into the Cerebral Cortex and Appropriately Project Axons to Subcortical Targets
Ideguchi, M., Palmer, T. D., Recht, L. D., & Weimann, J. M. (2010). Murine Embryonic Stem Cell-Derived Pyramidal Neurons Integrate into the Cerebral Cortex and Appropriately Project Axons to Subcortical Targets. JOURNAL OF NEUROSCIENCE, 30(3), 894-904.

Gender Disparity in the Rate of Partner Abandonment in Patients With Serious Medical Illness
Glantz, M. J., Chamberlain, M. C., Liu, Q., Hsieh, C.-C., Edwards, K. R., & Recht, L. (2009). Gender Disparity in the Rate of Partner Abandonment in Patients With Serious Medical Illness. CANCER, 115(22), 5237-5242.

Understanding the Origins of Gliomas and Developing Novel Therapies: Cerebrospinal Fluid and Subventricular Zone Interplay
Glantz, M., Kesari, S., Recht, L., Fleischhack, G., & Van Horn, A. (2009). Understanding the Origins of Gliomas and Developing Novel Therapies: Cerebrospinal Fluid and Subventricular Zone Interplay. SEMINARS IN ONCOLOGY, 36(4), S17-S24.

MOTEXAFIN GADOLINIUM COMBINED WITH PROMPT WHOLE BRAIN RADIOTHERAPY PROLONGS TIME TO NEUROLOGIC PROGRESSION IN NON-SMALL-CELL LUNG CANCER PATIENTS WITH BRAIN METASTASES: RESULTS OF A PHASE III TRIAL
Mehta, M. P., Shapiro, W. R., Phan, S. C., Gervais, R., Carrie, C., & Renschler, M. F. (2009). MOTEXAFIN GADOLINIUM COMBINED WITH PROMPT WHOLE BRAIN RADIOTHERAPY PROLONGS TIME TO NEUROLOGIC PROGRESSION IN NON-SMALL-CELL LUNG CANCER PATIENTS WITH BRAIN METASTASES: RESULTS OF A PHASE III TRIAL. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 73(4), 1069-1076.

EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors
Li, L., Dutra, A., Pak, E., Labrie, J. E., Gerstein, R. M., & Ross, A. H. (2009). EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. NEURO-ONCOLOGY, 11(1), 9-21.

Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice
Low, H. P., Greco, B., Tanahashi, Y., Gallant, J., Jones, S. N., & Schwartz, W. J. (2009). Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice. JOURNAL OF THE NEUROLOGICAL SCIENCES, 276(1-2), 133-137.

A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection
Jang, T., Sathy, B., Hsu, Y.-H., Merchant, M., Recht, B., & Recht, L. (2008). A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection. JOURNAL OF NEUROSURGERY, 108(4), 782-790.

Optimizing therapy for patients with brain metastases
Kuo, T., & Recht, L. (2006). Optimizing therapy for patients with brain metastases. SEMINARS IN ONCOLOGY, 33(3), 299-306.

Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea
Jang, T. C., Savarese, T., Low, H. P., Kim, S., Vogel, H., & Recht, L. (2006). Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. AMERICAN JOURNAL OF PATHOLOGY, 168(5), 1676-1685.

Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappa B-mediated resistance to O-6-alkylating agents in human glioblastomas
Bredel, M., Bredel, C., Juric, D., Duran, G. E., Yu, R. X., & Sikic, B. I. (2006). Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappa B-mediated resistance to O-6-alkylating agents in human glioblastomas. JOURNAL OF CLINICAL ONCOLOGY, 24(2), 274-287.

Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
Bredel, M., Bredel, C., Juric, D., Harsh, G. R., Vogel, H., & Sikic, B. I. (2005). Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. CANCER RESEARCH, 65(19), 8679-8689.

High-resolution genome-wide mapping of genetic alterations in human glial brain tumors
Bredel, M., Bredel, C., Juric, D., Harsh, G. R., Vogel, H., & Sikic, B. I. (2005). High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. CANCER RESEARCH, 65(10), 4088-4096.

Amplification of whole tumor genomes and geneby-gene mapping of genomic aberrations from limited sources of fresh-frozen and paraffin-embedded DNA
Bredel, M., Bredel, C., Juric, D., Kim, Y., Vogel, H., & Sikic, B. I. (2005). Amplification of whole tumor genomes and geneby-gene mapping of genomic aberrations from limited sources of fresh-frozen and paraffin-embedded DNA. JOURNAL OF MOLECULAR DIAGNOSTICS, 7(2), 171-182.

Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure
Savarese, T. M., Jang, T., Low, H. P., Salmonsen, R., Litofsky, N. S., & Recht, L. D. (2005). Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure. JOURNAL OF NEUROSURGERY, 102(1), 98-108.

Prevention and treatment of central nervous system involvement by non-Hodgkin's lymphoma: A review of the literature
Colocci, N., Glantz, M., & Recht, L. (2004). Prevention and treatment of central nervous system involvement by non-Hodgkin's lymphoma: A review of the literature. SEMINARS IN NEUROLOGY, 24(4), 395-404.

Treatment of neoplastic meningitis: what is the standard of care?
Recht, L., & Phuphanich, S. (2004). Treatment of neoplastic meningitis: what is the standard of care?. Expert review of neurotherapeutics, 4(4), S11-7.

Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis
Jang, T. C., Litofsky, N. S., Smith, T. W., Ross, A. H., & Recht, L. D. (2004). Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis. NEUROBIOLOGY OF DISEASE, 15(3), 544-552.

Differentiation prevents assessment of neural stem cell pluripotency after blastocyst injection
Greco, B., Low, H. P., Johnson, E. C., Salmonsen, R. A., Gallant, J., & Recht, L. D. (2004). Differentiation prevents assessment of neural stem cell pluripotency after blastocyst injection. STEM CELLS, 22(4), 600-608.