Richard J. Reimer, MD

General neurologist

Associate Professor of Neurology and, by courtesy, of Molecular and Cellular Physiology at the Palo Alto Veterans Administration Health Care System

Professional Education

Residency: UCSF School of Medicine (1995) CA

Board Certification: Neurology, American Board of Psychiatry and Neurology (1998)

Internship: UCSF School of Medicine (1992) CA

Medical Education: Emory University Hospital (1991) GA

Residency, UCSF, Neurology (1995)

MD, Emory University, Medicine (1991)

BA, Yale University, Mol Biochem and Biophysics (1985)

Honors & Awards

Brain and Immuno imaging Grant, Dana Foundation (2007-09)

Basil O'Connor Award, March of Dimes (2003-05)

Biochemistry to the Rescue: A CIC-2 Auxiliary Subunit Provides a Tangible Link to Leukodystrophy
Maduke, M. C., & Reimer, R. J. (2012). Biochemistry to the Rescue: A CIC-2 Auxiliary Subunit Provides a Tangible Link to Leukodystrophy. NEURON, 73(5), 855-857.

Glutamate biosensor imaging reveals dysregulation of glutamatergic pathways in a model of developmental cortical malformation.
Dulla, C. G., Tani, H., Brill, J., Reimer, R. J., & Huguenard, J. R. (2012). Glutamate biosensor imaging reveals dysregulation of glutamatergic pathways in a model of developmental cortical malformation. Neurobiology of disease, 49C, 232-246.

Structure-Function Studies of the SLC17 Transporter Sialin Identify Crucial Residues and Substrate-induced Conformational Changes
Courville, P., Quick, M., & Reimer, R. J. (2010). Structure-Function Studies of the SLC17 Transporter Sialin Identify Crucial Residues and Substrate-induced Conformational Changes. JOURNAL OF BIOLOGICAL CHEMISTRY, 285(25), 19316-19323.

Glutamine Is Required for Persistent Epileptiform Activity in the Disinhibited Neocortical Brain Slice
Tani, H., Dulla, C. G., Huguenard, J. R., & Reimer, R. J. (2010). Glutamine Is Required for Persistent Epileptiform Activity in the Disinhibited Neocortical Brain Slice. JOURNAL OF NEUROSCIENCE, 30(4), 1288-1300.

The Lysosomal Sialic Acid Transporter Sialin Is Required for Normal CNS Myelination
Prolo, L. M., Vogel, H., & Reimer, R. J. (2009). The Lysosomal Sialic Acid Transporter Sialin Is Required for Normal CNS Myelination. JOURNAL OF NEUROSCIENCE, 29(49), 15355-15365.

Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport
Zaia, K. A., & Reimer, R. J. (2009). Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport. JOURNAL OF BIOLOGICAL CHEMISTRY, 284(13), 8439-8448.

Imaging of glutamate in brain slices using FRET sensors
Dulla, C., Tani, H., Okumoto, S., Frommer, W. B., Reimer, R. J., & Fluguenard, J. R. (2008). Imaging of glutamate in brain slices using FRET sensors. JOURNAL OF NEUROSCIENCE METHODS, 168(2), 306-319.

G328E and G409E sialin missense mutations similarly impair transport activity, but differentially affect trafficking
Myall, N. J., Wreden, C. C., Wlizla, M., & Reimer, R. J. (2007). G328E and G409E sialin missense mutations similarly impair transport activity, but differentially affect trafficking. MOLECULAR GENETICS AND METABOLISM, 92(4), 371-374.

Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy
Tani, H., Bandrowski, A. E., Parada, I., Wynn, M., Huguenard, J. R., & Reimer, R. J. (2007). Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy. NEUROBIOLOGY OF DISEASE, 25(2), 230-238.

Biochemical and genetic analysis of ANK in arthritis and bone disease
Gurley, K. A., Reimer, R. J., & Kingsley, D. M. (2006). Biochemical and genetic analysis of ANK in arthritis and bone disease. AMERICAN JOURNAL OF HUMAN GENETICS, 79(6), 1017-1029.

Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors
Okumoto, S., Looger, L. L., Micheva, K. D., Reimer, R. J., Smith, S. J., & Frommer, W. B. (2005). Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(24), 8740-8745.

Varied mechanisms underlie the free sialic acid storage disorders
Wreden, C. C., Wlizla, M., & Reimer, R. J. (2005). Varied mechanisms underlie the free sialic acid storage disorders. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(2), 1408-1416.

Organic anion transport is the primary function of the SLC17/type I phosphate transporter family
Reimer, R. J., & Edwards, R. H. (2004). Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 447(5), 629-635.