Professional Summary
Education & Certifications
- Fellowship: Stanford University Cardiovascular Medicine Fellowship (2003) CA
- Residency: Stanford University Internal Medicine Residency (2000) CA
- Medical Education: Boston University School of Medicine (1997) MA
- Board Certification: American Board of Internal Medicine, Cardiovascular Disease (2003)
- BA, Cornell University, Biophysics (1989)
- MD, PhD, Boston University Med School, Biophysics (1997)
Publications
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Abnormal ECG after extensive maxillofacial surgery
Spin, J., & Hancock, E. W. (1999). Abnormal ECG after extensive maxillofacial surgery. HOSPITAL PRACTICE, 34(11), 27–28. -
The prognostic value of exercise testing in elderly men
Spin, J. M., PRAKASH, M., Froelicher, V. F., Partington, S., Marcus, R., Do, D., & Myers, J. (2002). The prognostic value of exercise testing in elderly men. AMERICAN JOURNAL OF MEDICINE, 112(6), 453–59. -
Early use of statins in acute coronary syndromes.
Spin, J. M., & Vagelos, R. H. (2002). Early use of statins in acute coronary syndromes. Current Cardiology Reports, 4(4), 289–97. -
Retinal evaluation of patients on chronic amiodarone therapy
Shaikh, S., Shaikh, N., Chun, S. H., Spin, J. M., Blumenkranz, M. S., & Marmor, M. F. (2003). Retinal evaluation of patients on chronic amiodarone therapy. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 23(3), 354–59. -
Treadmill scores in elderly men
Lai, S., Kaykha, A., Yamazaki, T., Goldstein, M., Spin, J. M., Myers, J., & Froelicher, V. F. (2004). Treadmill scores in elderly men. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 43(4), 606–15. -
Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice
Ishida, T., Choi, S. S. Y., Kundu, R. K., Spin, J., Yamashita, T., Hirata, K., … Quertermous, T. (2004). Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(43), 45085–92. -
Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation
Spin, J. M., Nallamshetty, S., Tabibiazar, R., Ashley, E. A., King, J. Y., Chen, M., … Quertermous, T. (2004). Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation. PHYSIOLOGICAL GENOMICS, 19(3), 292–302. -
Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease
Tabibiazar, R., Wagner, R. A., Spin, J. M., Ashley, E. A., Narasimhan, B., Rubin, E. M., … Quertermous, T. (2005). Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 25(2), 302–8. -
Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease
Tabibiazar, R., Wagner, R. A., Ashley, E. A., King, J. Y., Ferrara, R., Spin, J. M., … Quertermous, T. (2005). Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease. PHYSIOLOGICAL GENOMICS, 22(2), 213–26. -
Pathway analysis of coronary atherosclerosis
King, J. Y., Ferrara, R., Tabibiazar, R., Spin, J. M., Chen, M. M., Kuchinsky, A., … Ashley, E. A. (2005). Pathway analysis of coronary atherosclerosis. PHYSIOLOGICAL GENOMICS, 23(1), 103–18. -
Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation
Wu, J. C., Spin, J. M., Cao, F., Lin, S. A., Xie, X. Y., Gheysens, O., … Quertermous, T. (2006). Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. PHYSIOLOGICAL GENOMICS, 25(1), 29–38. -
Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes - Distinct responses to stimuli
Deng, D. X. F., Spin, J. M., Tsalenko, A., Vailaya, A., Ben-Dor, A., Yakhini, Z., … Quertermous, T. (2006). Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes - Distinct responses to stimuli. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 26(5), 1058–1065. -
Network analysis of human in-stent restenosis
Ashley, E. A., Ferrara, R., King, J. Y., Vailaya, A., Kuchinsky, A., He, X., … Quertermous, T. (2006). Network analysis of human in-stent restenosis. CIRCULATION, 114(24), 2644–54. -
Frontiers in nephrology: Genomic approaches to understanding the molecular basis of atherosclerosis
Ashley, E. A., Spin, J. M., Tabibiazar, R., & Quertermous, T. (2007). Frontiers in nephrology: Genomic approaches to understanding the molecular basis of atherosclerosis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 18(11), 2853–62. -
Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic Aneurysm Progression
Tedesco, M. M., Terashima, M., Blankenberg, F. G., Levashova, Z., Spin, J. M., Backer, M. V., … Dalman, R. L. (2009). Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic Aneurysm Progression. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 29(10), 1452-? -
New options with dabigatran etexilate in anticoagulant therapy.
Maegdefessel, L., Spin, J. M., Azuma, J., & Tsao, P. S. (2010). New options with dabigatran etexilate in anticoagulant therapy. Vascular Health and Risk Management, 6, 339–49. -
MicroRNA-26a Is a Novel Regulator of Vascular Smooth Muscle Cell Function
Leeper, N. J., Raiesdana, A., Kojima, Y., Chun, H. J., Azuma, J., Maegdefessel, L., … Spin, J. M. (2011). MicroRNA-26a Is a Novel Regulator of Vascular Smooth Muscle Cell Function. JOURNAL OF CELLULAR PHYSIOLOGY, 226(4), 1035–43. -
Gene Coexpression Network Topology of Cardiac Development, Hypertrophy, and Failure
Dewey, F. E., Perez, M. V., Wheeler, M. T., Watt, C., Spin, J., Langfelder, P., … Ashley, E. A. (2011). Gene Coexpression Network Topology of Cardiac Development, Hypertrophy, and Failure. CIRCULATION-CARDIOVASCULAR GENETICS, 4(1), 26–U129. -
Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300
Spin, J. M., Quertermous, T., & Tsao, P. S. (2010). Chromatin Remodeling Pathways in Smooth Muscle Cell Differentiation, and Evidence for an Integral Role for p300. PLOS ONE, 5(12). -
Gene Mutations and Familial Thoracic Aortic Aneurysms A Walk on the Mild Side
Spin, J. M. (2011). Gene Mutations and Familial Thoracic Aortic Aneurysms A Walk on the Mild Side. CIRCULATION-CARDIOVASCULAR GENETICS, 4(1), 4–6. -
Cardiac pressure overload hypertrophy is differentially regulated by beta-adrenergic receptor subtypes
Zhao, M., Fajardo, G., Urashima, T., Spin, J. M., Poorfarahani, S., Rajagopalan, V., … Bernstein, D. (2011). Cardiac pressure overload hypertrophy is differentially regulated by beta-adrenergic receptor subtypes. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 301(4), H1461–H1470. -
Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm
Spin, J. M., Hsu, M., Azuma, J., Tedesco, M. M., Deng, A., Dyer, J. S., … Tsao, P. S. (2011). Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm. PHYSIOLOGICAL GENOMICS, 43(17), 993–1003. -
In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium
Sheikh, A. Y., Huber, B. C., Narsinh, K. H., Spin, J. M., van der Bogt, K., de Almeida, P. E., … Wu, J. C. (2012). In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 92–102. -
miR-29b Participates in Early Aneurysm Development in Marfan Syndrome
Merk, D. R., Chin, J. T., Dake, B. A., Maegdefessel, L., Miller, M. O., Kimura, N., … Fischbein, M. P. (2012). miR-29b Participates in Early Aneurysm Development in Marfan Syndrome. CIRCULATION RESEARCH, 110(2), 312-? -
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development
Maegdefessel, L., Azuma, J., Toh, R., Merk, D. R., Deng, A., Chin, J. T., … Tsao, P. S. (2012). Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. JOURNAL OF CLINICAL INVESTIGATION, 122(2), 497–506. -
MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion
Maegdefessel, L., Azuma, J., Toh, R., Deng, A., Merk, D. R., Raiesdana, A., … Tsao, P. S. (2012). MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion. SCIENCE TRANSLATIONAL MEDICINE, 4(122). -
Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling
Spin, J. M., Maegdefessel, L., & Tsao, P. S. (2012). Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling. CARDIOVASCULAR RESEARCH, 95(2), 147–55. -
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Leeper, N. J., Raiesdana, A., Kojima, Y., Kundu, R. K., Cheng, H., Maegdefessel, L., … Quertermous, T. (2013). Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation. Arteriosclerosis, Thrombosis, and Vascular Biology, 33(1), e1–e10. -
Physiologic and molecular characterization of a murine model of right ventricular volume overload.
Reddy, S., Zhao, M., Hu, D.-Q., Fajardo, G., Katznelson, E., Punn, R., … Bernstein, D. (2013). Physiologic and molecular characterization of a murine model of right ventricular volume overload. American Journal of Physiology. Heart and Circulatory Physiology, 304(10), H1314–27. -
MicroRNAs in Abdominal Aortic Aneurysm.
Adam, M., Raaz, U., Spin, J. M., & Tsao, P. S. (2015). MicroRNAs in Abdominal Aortic Aneurysm. Current Vascular Pharmacology, 13(3), 280–90. -
CRYOELECTRON MICROSCOPY OF LOW-DENSITY-LIPOPROTEIN IN VITREOUS ICE
Spin, J. M., & Atkinson, D. (1995). CRYOELECTRON MICROSCOPY OF LOW-DENSITY-LIPOPROTEIN IN VITREOUS ICE. BIOPHYSICAL JOURNAL, 68(5), 2115–2123. -
Nicotine Accelerates the Expansion of Abdominal Aortic Aneurysms in Mice; A Potential Role for miR-21 and miR-26a
Maegdefessel, L., Azuma, J., Spin, J. M., Deng, A., McConnell, M. V., Dalman, R. L., & Tsao, P. S. (2010). Nicotine Accelerates the Expansion of Abdominal Aortic Aneurysms in Mice; A Potential Role for miR-21 and miR-26a. CIRCULATION, 122(21). -
Microarray Analysis Identifies miRNA-26a as a Regulator of Vascular Smooth Muscle Cell Phenotypic Modulation
Leeper, N. J., Raiesdana, A., Kojima, Y., Chun, H. J., Azuma, J., Kundu, R. K., … Spin, J. M. (2010). Microarray Analysis Identifies miRNA-26a as a Regulator of Vascular Smooth Muscle Cell Phenotypic Modulation. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30(11), E244–E244. -
Microrna-21 Regulates Expansion of Abdominal Aortic Aneurysms Through the PTEN/PI3K/AKT Pathway
Maegdefessel, L., Azuma, J., Deng, A., Toh, R. M., Merk, D. R., Raiesdana, A., … Tsao, P. S. (2011). Microrna-21 Regulates Expansion of Abdominal Aortic Aneurysms Through the PTEN/PI3K/AKT Pathway. CIRCULATION, 124(21). -
Nicotine-Augmented Abdominal Aortic Aneurysms are Regulated by MicroRNA-29b
Maegdefessel, L., Azuma, J., Merk, D. R., Toh, R. M., Deng, A., Chin, J. P., … Tsao, P. S. (2011). Nicotine-Augmented Abdominal Aortic Aneurysms are Regulated by MicroRNA-29b. CIRCULATION, 124(21). -
Is the Duke Treadmill Score appropriate in the elderly?
Lai, S. R., Kaykha, A., Yamazaki, T., Spin, J., Goldstein, M., Froelicher, V. F., & Myers, J. (2003). Is the Duke Treadmill Score appropriate in the elderly? JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 51(4), S213–S213. -
MicroRNA-24 controls abdominal aortic aneurysm development through regulation of YKL-40
Maegdefessel, L., Raaz, U., Adam, M., Spin, J., Eriksson, P., Hamsten, A., & Tsao, P. (2013). MicroRNA-24 controls abdominal aortic aneurysm development through regulation of YKL-40. SPRINGER. -
Micromanaging Abdominal Aortic Aneurysms
Maegdefessel, L., Spin, J. M., Adam, M., Raaz, U., Toh, R., Nakagami, F., & Tsao, P. S. (2013). Micromanaging Abdominal Aortic Aneurysms. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 14(7), 14374–14394. -
Hemodynamic regulation of reactive oxygen species: implications for vascular diseases.
Raaz, U., Toh, R., Maegdefessel, L., Adam, M., Nakagami, F., Emrich, F. C., … Tsao, P. S. (2014). Hemodynamic regulation of reactive oxygen species: implications for vascular diseases. Antioxidants & Redox Signaling, 20(6), 914–28. -
Dichloroacetate prevents restenosis in preclinical animal models of vessel injury.
Deuse, T., Hua, X., Wang, D., Maegdefessel, L., Heeren, J., Scheja, L., … Schrepfer, S. (2014). Dichloroacetate prevents restenosis in preclinical animal models of vessel injury. Nature, 509(7502), 641–44. -
New ways to dismantle a ticking time bomb: microRNA 712/205 and abdominal aortic aneurysm development.
Maegdefessel, L., Spin, J. M., & Tsao, P. S. (2014). New ways to dismantle a ticking time bomb: microRNA 712/205 and abdominal aortic aneurysm development. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(7), 1339–40. -
Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.
Hennigs, J. K., Müller, J., Adam, M., Spin, J. M., Riedel, E., Graefen, M., … Minner, S. (2014). Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse. PloS One, 9(7). -
miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.
Maegdefessel, L., Spin, J. M., Raaz, U., Eken, S. M., Toh, R., Azuma, J., … Tsao, P. S. (2014). miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development. Nature Communications, 5, 5214-? -
miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development
Maegdefessel, L., Spin, J. M., Raaz, U., Eken, S. M., Toh, R., Azuma, J., … Tsao, P. S. (2014). miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development. NATURE COMMUNICATIONS, 5. -
Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure.
Adam, M., Meyer, S., Knors, H., Klinke, A., Radunski, U. K., Rudolph, T. K., … Baldus, S. (2015). Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure. Scientific Reports, 5, 9704-? -
Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development
Raaz, U., Zoellner, A. M., Schellinger, I. N., Toh, R., Nakagami, F., Brandt, M., … Tsao, P. S. (2015). Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development. CIRCULATION, 131(20), 1783–95. -
Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus
Raaz, U., Schellinger, I. N., Chernogubova, E., Warnecke, C., Kayama, Y., Penov, K., … Tsao, P. S. (2015). Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus. CIRCULATION RESEARCH, 117(6), 513–24. -
Local MicroRNA Modulation Using a Novel Anti-miR21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis
Wang, D., Deuse, T., Stubbendorff, M., Chernogubova, E., Erben, R. G., Eken, S. M., … Maegdefessel, L. (2015). Local MicroRNA Modulation Using a Novel Anti-miR21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 35(9), 1945–53. -
Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm.
Spin, J. M., & Tsao, P. S. (2014). Battle of the bulge: miR-195 versus miR-29b in aortic aneurysm. Circulation Research, 115(10), 812–13. -
Diabetic Cardiovascular Disease Induced by Oxidative Stress
Kayama, Y., Raaz, U., Jagger, A., Adam, M., Schellinger, I. N., Sakamoto, M., … Tsao, P. S. (2015). Diabetic Cardiovascular Disease Induced by Oxidative Stress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 16(10), 25234–63. -
CDKN2B Regulates TGFß Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels.
Nanda, V., Downing, K. P., Ye, J., Xiao, S., Kojima, Y., Spin, J. M., … Leeper, N. J. (2016). CDKN2B Regulates TGFß Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels. Circulation Research, 118(2), 230–40. -
Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression.
Azuma, J., Wong, R. J., Morisawa, T., Hsu, M., Maegdefessel, L., Zhao, H., … Tsao, P. S. (2016). Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression. PloS One, 11(2). -
The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation
Deuse, T., Hua, X., Stubbendorff, M., Spin, J. M., Neofytou, E., Taylor, V., … Schrepfer, S. (2016). The Selective JAK1/3-Inhibitor R507 Mitigates Obliterative Airway Disease Both With Systemic Administration and Aerosol Inhalation. TRANSPLANTATION, 100(5), 1022–31. -
Role of microRNAs on Blood Brain Barrier Dysfunction in Vascular Cognitive Impairment.
Toyama, K., Spin, J. M., & Tsao, P. S. (2016). Role of microRNAs on Blood Brain Barrier Dysfunction in Vascular Cognitive Impairment. Current Drug Delivery, -? -
Oxidized (non)-regenerated cellulose affects fundamental cellular processes of wound healing
Wagenhaeuser, M. U., Mulorz, J., Ibing, W., Simon, F., Spin, J. M., Schelzig, H., & Oberhuber, A. (2016). Oxidized (non)-regenerated cellulose affects fundamental cellular processes of wound healing. SCIENTIFIC REPORTS, 6. -
A Pilot Study: The Beneficial Effects of Combined Statinexercise Therapy on Cognitive Function in Patients with Coronary Artery Disease and Mild Cognitive Decline
Toyama, K., Sugiyama, S., Oka, H., Hamada, M., Iwasaki, Y., Horio, E., … Ogawa, H. (2017). A Pilot Study: The Beneficial Effects of Combined Statinexercise Therapy on Cognitive Function in Patients with Coronary Artery Disease and Mild Cognitive Decline. INTERNAL MEDICINE, 56(6), 641–49. -
MicroRNA-Mediated Therapy Modulating Blood-Brain Barrier Disruption Improves Vascular Cognitive Impairment.
Toyama, K., Spin, J. M., Deng, A. C., Huang, T.-T., Wei, K., Wagenhauser, M. U., … Tsao, P. S. (2018). MicroRNA-Mediated Therapy Modulating Blood-Brain Barrier Disruption Improves Vascular Cognitive Impairment. Arteriosclerosis, Thrombosis, and Vascular Biology. -
Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm.
Adam, M., Kooreman, N., Jagger, A., Wagenhaeuser, M. U., Mehrkens, D., Wang, Y., … Tsao, P. S. (2018). Systemic Upregulation of IL-10 (Interleukin-10) Using a Nonimmunogenic Vector Reduces Growth and Rate of Dissecting Abdominal Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology. -
H19 Induces Abdominal Aortic Aneurysm Development and Progression.
Li, D. Y., Busch, A., Jin, H., Chernogubova, E., Pelisek, J., Karlsson, J., … Maegdefessel, L. (2018). H19 Induces Abdominal Aortic Aneurysm Development and Progression. Circulation. -
Open surgery for iliofemoral deep vein thrombosis with temporary arteriovenous fistula remains valuable.
Wagenhäuser, M. U., Sadat, H., Dueppers, P., Meyer-Janiszewski, Y. K., Spin, J. M., Schelzig, H., & Duran, M. (2017). Open surgery for iliofemoral deep vein thrombosis with temporary arteriovenous fistula remains valuable. Phlebology, 268355517736437. -
Chronic Mesenteric Ischemia: Patient Outcomes Using Open Surgical Revascularization.
Wagenhäuser, M. U., Meyer-Janiszewski, Y. K., Dueppers, P., Spin, J. M., Floros, N., Schelzig, H., & Duran, M. (2017). Chronic Mesenteric Ischemia: Patient Outcomes Using Open Surgical Revascularization. Digestive Surgery. -
Non-coding RNAs in aneurysmal aortopathy.
Spin, J. M., Li, D. Y., Maegdefessel, L., & Tsao, P. S. (2018). Non-coding RNAs in aneurysmal aortopathy. Vascular Pharmacology. -
Decoding the Genomics of Abdominal Aortic Aneurysm.
Li, J., Pan, C., Zhang, S., Spin, J. M., Deng, A., Leung, L. L., … Snyder, M. (2018). Decoding the Genomics of Abdominal Aortic Aneurysm. Cell, 174(6), 1361. -
Clinical outcomes after direct and indirect surgical venous thrombectomy for inferior vena cava thrombosis.
Wagenhauser, M. U., Dimopoulos, C., Antakyali, K., Meyer-Janiszewski, Y. K., Mulorz, J., Ibing, W., … Duran, M. (2019). Clinical outcomes after direct and indirect surgical venous thrombectomy for inferior vena cava thrombosis. Journal of Vascular Surgery. Venous and Lymphatic Disorders. -
Response to Letters Regarding Article, "Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development"
Raaz, U., Zoellner, A. M., Schellinger, I. N., Toh, R., Nakagami, F., Brandt, M., … Tsao, P. S. (2016). Response to Letters Regarding Article, "Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development". CIRCULATION, 133(1), E11–E12. -
Chronic Nicotine Exposure Induces Murine Aortic Remodeling and Stiffness Segmentation-Implications for Abdominal Aortic Aneurysm Susceptibility.
Wagenhäuser, M. U., Schellinger, I. N., Yoshino, T., Toyama, K., Kayama, Y., Deng, A., … Tsao, P. S. (2018). Chronic Nicotine Exposure Induces Murine Aortic Remodeling and Stiffness Segmentation-Implications for Abdominal Aortic Aneurysm Susceptibility. Frontiers in Physiology, 9, 1459. -
Non-coding RNAs in aneurysmal aortopathy
Spin, J. M., Li, D. Y., Maegdefessel, L., & Tsao, P. S. (2019). Non-coding RNAs in aneurysmal aortopathy. VASCULAR PHARMACOLOGY, 114, 110–21. -
Therapeutic perspective on vascular cognitive impairment.
Toyama, K., Spin, J. M., Mogi, M., & Tsao, P. S. (2019). Therapeutic perspective on vascular cognitive impairment. Pharmacological Research, 104266. -
Controlled isoflurane anesthesia exposure is required for reliable behavioral testing in murine surgical models.
Toyama, K., Spin, J. M., Abe, Y., Suzuki, Y., Deng, A. C., Wagenhauser, M. U., … Mogi, M. (2019). Controlled isoflurane anesthesia exposure is required for reliable behavioral testing in murine surgical models. Journal of Pharmacological Sciences. -
Long noncoding RNAs in key cellular processes involved in aortic aneurysms.
Wu, Z.-Y. Y., Trenner, M., Boon, R. A., Spin, J. M., & Maegdefessel, L. (2019). Long noncoding RNAs in key cellular processes involved in aortic aneurysms. Atherosclerosis, 292, 112–18. -
Involvement of Myeloid Cells and Non-Coding RNA in Abdominal Aortic Aneurysm Disease.
Knappich, C., Spin, J. M., Eckstein, H.-H. H., Tsao, P. S., & Maegdefessel, L. (2020). Involvement of Myeloid Cells and Non-Coding RNA in Abdominal Aortic Aneurysm Disease. Antioxidants & Redox Signaling. -
Low-Normal Platelets and Decreasing Platelets Are Risk Factors for Hearing Impairment Development.
Abe, Y., Toyama, K., Kazurayama, M., Tanaka, S., Yamaizumi, M., Ueno, M., … Mogi, M. (2020). Low-Normal Platelets and Decreasing Platelets Are Risk Factors for Hearing Impairment Development. The Laryngoscope. -
Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice.
Mulorz, J., Spin, J. M., Beck, H. C., Tha Thi, M. L., Wagenhäuser, M. U., Rasmussen, L. M., … Steffensen, L. B. (2020). Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice. Atherosclerosis, 311, 73–83. -
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Klarin, D., Verma, S. S., Judy, R., Dikilitas, O., Wolford, B. N., Paranjpe, I., … Tsao, P. S. (2020). Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program. Circulation. -
Immunomodulation therapy using tolerogenic macrophages in a rodent model of pulmonary hypertension.
Guihaire, J., Deuse, T., Wang, D., Spin, J. M., Blankenberg, F. G., Fadel, E., … Schrepfer, S. (2021). Immunomodulation therapy using tolerogenic macrophages in a rodent model of pulmonary hypertension. Stem Cells and Development. -
Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness.
Toyama, K., Igase, M., Spin, J. M., Abe, Y., Javkhlant, A., Okada, Y., … Mogi, M. (2021). Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness. Circulation Reports, 3(3), 170–77. -
MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening.
Schellinger, I. N., Wagenhauser, M., Chodisetti, G., Mattern, K., Dannert, A., Petzold, A., … Raaz, U. (2021). MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening. Molecular Therapy. Nucleic Acids, 24, 188–99. -
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm.
Mulorz, J., Shayan, M., Hu, C., Alcazar, C., Chan, A. H., Briggs, M., … Huang, N. F. (2021). peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. Biomaterials Science. -
Role of MicroRNAs in acceleration of vascular endothelial senescence.
Toyama, K., Spin, J. M., Deng, A. C., Abe, Y., Tsao, P. S., & Mogi, M. (2022). Role of MicroRNAs in acceleration of vascular endothelial senescence. Biochemistry and Biophysics Reports, 30, 101281. -
E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1.
Mulorz, J., Spin, J. M., Mulorz, P., Wagenhauser, M., Deng, A., Mattern, K., … Tsao, P. S. (2022). E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1. Cardiovascular Research. -
Message to researchers: the characteristic absence of a posterior communicating artery is easily lost in the gerbil.
Abe, Y., Toyama, K., Shinohara, A., Nagura-Kato, G. A., Ikai, Y., Koshimoto, C., … Hato, N. (2022). Message to researchers: the characteristic absence of a posterior communicating artery is easily lost in the gerbil. Anatomical Science International. -
Time-dependent effects of cellulose and gelatin-based hemostats on cellular processes of wound healing
Wagenhaeuser, M. U., Garabet, W., van Bonn, M., Ibing, W., Mulorz, J., Rhee, Y. H., … Simon, F. (2023). Time-dependent effects of cellulose and gelatin-based hemostats on cellular processes of wound healing. ARCHIVES OF MEDICAL SCIENCE, 19(1), 194–202. -
Time-dependent effects of cellulose and gelatin-based hemostats on cellular processes of wound healing.
Wagenhäuser, M. U., Garabet, W., van Bonn, M., Ibing, W., Mulorz, J., Rhee, Y. H., … Simon, F. (2023). Time-dependent effects of cellulose and gelatin-based hemostats on cellular processes of wound healing. Archives of Medical Science : AMS, 19(1), 194–202. -
IS IT POSSIBLE TO ACCELERATE SENESCENCE IN THE VASCULAR ENDOTHELIAL CELL BY MODULATING SEVERAL MICRORNAS?
Toyama, K., Spin, J. M., Tsao, P. S., & Mogi, M. (2023). IS IT POSSIBLE TO ACCELERATE SENESCENCE IN THE VASCULAR ENDOTHELIAL CELL BY MODULATING SEVERAL MICRORNAS? JOURNAL OF HYPERTENSION. LIPPINCOTT WILLIAMS & WILKINS. -
Serum microRNA-501-3p is a potential diagnostic tool for detecting mild cognitive impairment: Ehime genome study.
Toyama, K., Spin, J. M., Tsao, P. S., Maruyama, K., Osawa, H., Mogi, M., & Takata, Y. (2023). Serum microRNA-501-3p is a potential diagnostic tool for detecting mild cognitive impairment: Ehime genome study. Journal of Neurochemistry. -
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target.
Roychowdhury, T., Klarin, D., Levin, M. G., Spin, J. M., Rhee, Y. H., Deng, A., … Damrauer, S. M. (2023). Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nature Genetics. -
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
Roychowdhury, T., Klarin, D., Levin, M. G., Spin, J. M., Rhee, Y. H., Deng, A., … Samani, N. J. (2023). Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. NATURE GENETICS. -
Crosstalk of platelets with macrophages and fibroblasts aggravates inflammation, aortic wall stiffening, and osteopontin release in abdominal aortic aneurysm
Wagenhaeuser, M. U., Mulorz, J., Krott, K. J., Bosbach, A., Feige, T., Rhee, Y. H., … Elvers, M. (2023). Crosstalk of platelets with macrophages and fibroblasts aggravates inflammation, aortic wall stiffening, and osteopontin release in abdominal aortic aneurysm. CARDIOVASCULAR RESEARCH. -
Lack of ATP2B1 in CD4+ T Cells Causes Colitis.
Javkhlant, A., Toyama, K., Abe, Y., Spin, J. M., & Mogi, M. (2024). Lack of ATP2B1 in CD4+ T Cells Causes Colitis. Inflammatory Bowel Diseases.
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Stanford, CAAortic Disease Center
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