Pituitary Adenomas Can Appear as Hypermetabolic Lesions in 18F-FDG PET Imaging JOURNAL OF NEUROIMAGING Ryu, S. I., Tafti, B. A., Skirboll, S. L. 2010; 20 (4): 393-396


The 2-deoxy-2-[(18) F] fluoro-D-glucose positron emission tomography (FDG-PET) scan is commonly used in detection and staging of many malignant neoplasms. However, several benign or non-neoplastic conditions avidly accumulate (18) F-FDG, causing ambiguity in interpretation of results. It is unknown whether pituitary adenomas uptake (18) F-FDG and appear positive in PET imaging. Here, we present 2 cases of benign pituitary adenoma with elevated metabolic activity in (18) F-FDG PET scan.Medical, neurologic, and psychiatric histories; physical examination findings; laboratory work up results; and pathologic and imaging studies were documented.The (18) F-FDG-PET images revealed foci of marked FDG uptake in pituitary adenomas of 2 patients.Pituitary micro- and macro-adenomas may present as hypermetabolic foci on (18) F-FDG PET scan.

View details for DOI 10.1111/j.1552-6569.2008.00347.x

View details for Web of Science ID 000282574100015

View details for PubMedID 19453834