Cornelia Weyand

Professor of Medicine (Immunology and Rheumatology)

Professional Education

Professional Education: University of Heidelberg (1988) Germany

Fellowship: Stanford University - Immunology/Rheumatology (1986) CA

Residency: Hannover Medical School (1984)

Fellowship: Heidelberg University German Cancer Research Center (1981)

Professional Education: University of Bonn (1980)

Medical Education: University of Aachen (1979)

Administrative Appointments

Chief, Division of Immunology and Rheumatology, Stanford University School of Medicine (2013 - Present)

Targets of Immune Regeneration in Rheumatoid Arthritis
Hohensinner, P. J., Goronzy, J. J., & Weyand, C. M. (2014). Targets of Immune Regeneration in Rheumatoid Arthritis. MAYO CLINIC PROCEEDINGS, 89(4), 563-575.

Understanding immunosenescence to improve responses to vaccines
Goronzy, J. J., & Weyand, C. M. (2013). Understanding immunosenescence to improve responses to vaccines. NATURE IMMUNOLOGY, 14(5), 428-436.

IL-7-and IL-15-Mediated TCR Sensitization Enables T Cell Responses to Self-Antigens
Deshpande, P., Cavanagh, M. M., Le Saux, S., Singh, K., Weyand, C. M., & Goronzy, J. J. (2013). IL-7-and IL-15-Mediated TCR Sensitization Enables T Cell Responses to Self-Antigens. JOURNAL OF IMMUNOLOGY, 190(4), 1416-1423.

The janus head of T cell aging - autoimmunity and immunodeficiency.
Goronzy, J. J., Li, G., Yang, Z., & Weyand, C. M. (2013). The janus head of T cell aging - autoimmunity and immunodeficiency. Frontiers in immunology, 4, 131-?.

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
Li, G., Yu, M., Lee, W.- woo, Tsang, M., Krishnan, E., & Goronzy, J. J. (2012). Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. NATURE MEDICINE, 18(10), 1518-U113.

Signaling pathways in aged T cells - A reflection of T cell differentiation, cell senescence and host environment
Goronzy, J. J., Li, G., Yu, M., & Weyand, C. M. (2012). Signaling pathways in aged T cells - A reflection of T cell differentiation, cell senescence and host environment. SEMINARS IN IMMUNOLOGY, 24(5), 365-372.

The Immunopathology of Giant Cell Arteritis: Diagnostic and Therapeutic Implications
Weyand, C. M., Liao, Y. J., & Goronzy, J. J. (2012). The Immunopathology of Giant Cell Arteritis: Diagnostic and Therapeutic Implications. JOURNAL OF NEURO-OPHTHALMOLOGY, 32(3), 259-265.

CD8(+) CD45RA(+) CCR7(+) FOXP3(+) T Cells with Immunosuppressive Properties: A Novel Subset of Inducible Human Regulatory T Cells
Suzuki, M., Jagger, A. L., Konya, C., Shimojima, Y., Pryshchep, S., & Weyand, C. M. (2012). CD8(+) CD45RA(+) CCR7(+) FOXP3(+) T Cells with Immunosuppressive Properties: A Novel Subset of Inducible Human Regulatory T Cells. JOURNAL OF IMMUNOLOGY, 189(5), 2118-2130.

Chronic inflammation and aging: DNA damage tips the balance
Cavanagh, M. M., Weyand, C. M., & Goronzy, J. J. (2012). Chronic inflammation and aging: DNA damage tips the balance. CURRENT OPINION IN IMMUNOLOGY, 24(4), 488-493.

Immune aging and autoimmunity
Goronzy, J. J., & Weyand, C. M. (2012). Immune aging and autoimmunity. CELLULAR AND MOLECULAR LIFE SCIENCES, 69(10), 1615-1623.

Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age
Yu, M., Li, G., Lee, W.- woo, Yuan, M., Cui, D., & Goronzy, J. J. (2012). Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(15), E879-E888.

Dampened ERK signaling in hematopoietic progenitor cells in rheumatoid arthritis
Colmegna, I., Pryshchep, S., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2012). Dampened ERK signaling in hematopoietic progenitor cells in rheumatoid arthritis. CLINICAL IMMUNOLOGY, 143(1), 73-82.

Mechanisms of immunosenescence: lessons from models of accelerated immune aging
Le Saux, S., Weyand, C. M., & Goronzy, J. J. (2012). Mechanisms of immunosenescence: lessons from models of accelerated immune aging. YEAR IN IMMUNOLOGY, 1247, 69-82.

Telomere Dysfunction, Autoimmunity and Aging
Hohensinner, P. J., Goronzy, J. J., & Weyand, C. M. (2011). Telomere Dysfunction, Autoimmunity and Aging. AGING AND DISEASE, 2(6), 524-537.

Finding Balance: T cell Regulatory Receptor Expression during Aging
Cavanagh, M. M., Qi, Q., Weyand, C. M., & Goronzy, J. J. (2011). Finding Balance: T cell Regulatory Receptor Expression during Aging. AGING AND DISEASE, 2(5), 398-413.

Magnetic Resonance Angiography in Extracranial Giant Cell Arteritis
Koenigkam-Santos, M., Sharma, P., Kalb, B., Oshinski, J. N., Weyand, C. M., & Martin, D. R. (2011). Magnetic Resonance Angiography in Extracranial Giant Cell Arteritis. JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 17(6), 306-310.

Inflammation and cardiac outcome
Hohensinner, P. J., Niessner, A., Huber, K., Weyand, C. M., & Wojta, J. (2011). Inflammation and cardiac outcome. CURRENT OPINION IN INFECTIOUS DISEASES, 24(3), 259-264.

Regulation of T cell receptor signaling by activation-induced zinc influx
Yu, M., Lee, W.- woo, Tomar, D., Pryshchep, S., Czesnikiewicz-Guzik, M., & Goronzy, J. J. (2011). Regulation of T cell receptor signaling by activation-induced zinc influx. JOURNAL OF EXPERIMENTAL MEDICINE, 208(4), 775-785.

Inflammation, Immunity, and Hypertension
Harrison, D. G., Guzik, T. J., Lob, H. E., Madhur, M. S., Marvar, P. J., & Weyand, C. M. (2011). Inflammation, Immunity, and Hypertension. HYPERTENSION, 57(2), 132-140.

Haematopoietic stem and progenitor cells in rheumatoid arthritis
Colmegna, I., & Weyand, C. M. (2011). Haematopoietic stem and progenitor cells in rheumatoid arthritis. RHEUMATOLOGY, 50(2), 252-260.

Blocking the NOTCH Pathway Inhibits Vascular Inflammation in Large-Vessel Vasculitis
Piggott, K., Deng, J., Warrington, K., Younge, B., Kubo, J. T., & Weyand, C. M. (2011). Blocking the NOTCH Pathway Inhibits Vascular Inflammation in Large-Vessel Vasculitis. CIRCULATION, 123(3), 309-U180.

Giant cell arteritis: immune and vascular aging as disease risk factors
Mohan, S. V., Liao, Y. J., Kim, J. W., Goronzy, J. J., & Weyand, C. M. (2011). Giant cell arteritis: immune and vascular aging as disease risk factors. ARTHRITIS RESEARCH & THERAPY, 13(4).

IFN-gamma and IL-17: the two faces of T-cell pathology in giant cell arteritis
Weyand, C. M., Younge, B. R., & Goronzy, J. J. (2011). IFN-gamma and IL-17: the two faces of T-cell pathology in giant cell arteritis. CURRENT OPINION IN RHEUMATOLOGY, 23(1), 43-49.

Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension
Vinh, A., Chen, W., Blinder, Y., Weiss, D., Taylor, W. R., & Guzik, T. J. (2010). Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension. CIRCULATION, 122(24), 2529-2537.

Statins reduce endothelial cell apoptosis via inhibition of TRAIL expression on activated CD4 T cells in acute coronary syndrome
Sato, K., Nuki, T., Gomita, K., Weyand, C. M., & Hagiwara, N. (2010). Statins reduce endothelial cell apoptosis via inhibition of TRAIL expression on activated CD4 T cells in acute coronary syndrome. ATHEROSCLEROSIS, 213(1), 33-39.

DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis
Shao, L., Goronzy, J. J., & Weyand, C. M. (2010). DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis. EMBO MOLECULAR MEDICINE, 2(10), 415-427.

Immune Aging and Rheumatoid Arthritis
Goronzy, J. J., Shao, L., & Weyand, C. M. (2010). Immune Aging and Rheumatoid Arthritis. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 36(2), 297-?.

Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages
Lamar, D. L., Weyand, C. M., & Goronzy, J. J. (2010). Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages. BLOOD, 115(16), 3278-3286.

Insufficient Deactivation of the Protein Tyrosine Kinase Lck Amplifies T-Cell Responsiveness in Acute Coronary Syndrome
Pryshchep, S., Goronzy, J. J., Parashar, S., & Weyand, C. M. (2010). Insufficient Deactivation of the Protein Tyrosine Kinase Lck Amplifies T-Cell Responsiveness in Acute Coronary Syndrome. CIRCULATION RESEARCH, 106(4), 769-U269.

Th17 and Th1 T-Cell Responses in Giant Cell Arteritis
Deng, J., Younge, B. R., Olshen, R. A., Goronzy, J. J., & Weyand, C. M. (2010). Th17 and Th1 T-Cell Responses in Giant Cell Arteritis. CIRCULATION, 121(7), 906-U107.

Telomeres and Immunological Diseases of Aging
Andrews, N. P., Fujii, H., Goronzy, J. J., & Weyand, C. M. (2010). Telomeres and Immunological Diseases of Aging. GERONTOLOGY, 56(4), 390-403.

Dendritic cells in atherosclerotic disease
Niessner, A., & Weyand, C. M. (2010). Dendritic cells in atherosclerotic disease. CLINICAL IMMUNOLOGY, 134(1), 25-32.

ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis
Singh, K., Deshpande, P., Pryshchep, S., Colmegna, I., Liarski, V., & Goronzy, J. J. (2009). ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis. JOURNAL OF IMMUNOLOGY, 183(12), 8258-8267.

Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells
Li, G., Yu, M., Weyand, C. M., & Goronzy, J. J. (2009). Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells. BLOOD, 114(16), 3422-3430.

Rejuvenating the immune system in rheumatoid arthritis
Weyand, C. M., Fujii, H., Shao, L., & Goronzy, J. J. (2009). Rejuvenating the immune system in rheumatoid arthritis. NATURE REVIEWS RHEUMATOLOGY, 5(10), 583-588.

Treating autoimmune disease by targeting CD8(+) T suppressor cells
Konya, C., Goronzy, J. J., & Weyand, C. M. (2009). Treating autoimmune disease by targeting CD8(+) T suppressor cells. EXPERT OPINION ON BIOLOGICAL THERAPY, 9(8), 951-965.

Clinicopathologic Correlations in Giant Cell Arteritis A Retrospective Study of 107 Cases
Zhou, L., Luneau, K., Weyand, C. M., Biousse, V., Newman, N. J., & Grossniklaus, H. E. (2009). Clinicopathologic Correlations in Giant Cell Arteritis A Retrospective Study of 107 Cases. OPHTHALMOLOGY, 116(8), 1574-1580.

Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis
Shao, L., Fujii, H., Colmegna, I., Oishi, H., Goronzy, J. J., & Weyand, C. M. (2009). Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis. JOURNAL OF EXPERIMENTAL MEDICINE, 206(6), 1435-1449.

Telomerase insufficiency in rheumatoid arthritis
Fujii, H., Shao, L., Colmegna, I., Goronzy, J. J., & Weyand, C. M. (2009). Telomerase insufficiency in rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(11), 4360-4365.

Pathogenesis of medium- and large-vessel vasculitis
Weyand, C. M., & Goronzy, J. J. (2009). Pathogenesis of medium- and large-vessel vasculitis. ZEITSCHRIFT FUR RHEUMATOLOGIE, 68(2), 100-?.

Toll-Like Receptors 4 and 5 Induce Distinct Types of Vasculitis
Deng, J., Ma-Krupa, W., Gewirtz, A. T., Younge, B. R., Goronzy, J. J., & Weyand, C. M. (2009). Toll-Like Receptors 4 and 5 Induce Distinct Types of Vasculitis. CIRCULATION RESEARCH, 104(4), 488-U139.

Developments in the scientific understanding of rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2009). Developments in the scientific understanding of rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY, 11(5).

Vascular damage in giant cell arteritis
Piggott, K., Biousse, V., Newman, N. J., Goronzy, J. J., & Weyand, C. M. (2009). Vascular damage in giant cell arteritis. AUTOIMMUNITY, 42(7), 596-604.

Age-Dependent Signature of Metallothionein Expression in Primary CD4 T Cell Responses Is Due to Sustained Zinc Signaling
Lee, W.- woo, Cui, D., Czesnikiewicz-Guzik, M., Vencio, R. Zn., Shmulevich, I., & Goronzy, J. J. (2008). Age-Dependent Signature of Metallothionein Expression in Primary CD4 T Cell Responses Is Due to Sustained Zinc Signaling. REJUVENATION RESEARCH, 11(6), 1001-1011.

Inhibitory CD8(+) T cells in autoimmune disease
Suzuki, M., Konya, C., Goronzy, J. J., & Weyand, C. M. (2008). Inhibitory CD8(+) T cells in autoimmune disease. HUMAN IMMUNOLOGY, 69(11), 781-789.

T-cell co-stimulatory pathways in autoimmunity
Goronzy, J. J., & Weyand, C. M. (2008). T-cell co-stimulatory pathways in autoimmunity. ARTHRITIS RESEARCH & THERAPY, 10.

T cells in arteritis and atherosclerosis
Weyand, C. M., Younge, B. R., & Goronzy, J. J. (2008). T cells in arteritis and atherosclerosis. CURRENT OPINION IN LIPIDOLOGY, 19(5), 469-477.

Vessel-specific Toll-like receptor profiles in human medium and large arteries
Pryshchep, O., Ma-Krupa, W., Younge, B. R., Goronzy, J. J., & Weyand, C. M. (2008). Vessel-specific Toll-like receptor profiles in human medium and large arteries. CIRCULATION, 118(12), 1276-1284.

Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells
Li, G., Weyand, C. M., & Goronzy, J. J. (2008). Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells. JOURNAL OF LEUKOCYTE BIOLOGY, 84(3), 824-834.

The treatment of giant cell arteritis.
Fraser, J. A., Weyand, C. M., Newman, N. J., & Biousse, V. (2008). The treatment of giant cell arteritis. Reviews in neurological diseases, 5(3), 140-152.

Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis
Colmegna, I., Diaz-Borjon, A., Fujii, H., Schaefer, L., Goronzy, J. J., & Weyand, C. M. (2008). Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 58(4), 990-1000.

TLR-mediated induction of negative regulatory ligands on dendritic cells
Groschel, S., Piggott, K. D., Vaglio, A., Ma-Krupa, W., Singh, K., & Weyand, C. M. (2008). TLR-mediated induction of negative regulatory ligands on dendritic cells. JOURNAL OF MOLECULAR MEDICINE-JMM, 86(4), 443-455.

T cell subset-specific susceptibility to aging
Czesnikiewicz-Guzik, M., Lee, W.- woo, Cui, D., Hiruma, Y., Lamar, D. L., & Goronzy, J. J. (2008). T cell subset-specific susceptibility to aging. CLINICAL IMMUNOLOGY, 127(1), 107-118.

Vessel wall-embedded dendritic cells induce T-Cell autoreactivity and initiate vascular inflammation
Han, J. W., Shimada, K., Ma-Krupa, W., Johnson, T. L., Nerem, R. M., & Weyand, C. M. (2008). Vessel wall-embedded dendritic cells induce T-Cell autoreactivity and initiate vascular inflammation. CIRCULATION RESEARCH, 102(5), 546-553.

Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis
Singh, K., Colmegna, I., He, X., Weyand, C. M., & Goronzy, J. J. (2008). Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 180(3), 1971-1978.

Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and toll-like receptor 4 ligands in the atherosclerotic plaque
Niessner, A., Shin, M. S., Pryshchep, O., Goronzy, J. J., Chaikof, E. L., & Weyand, C. M. (2007). Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and toll-like receptor 4 ligands in the atherosclerotic plaque. CIRCULATION, 116(18), 2043-2052.

Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis
Sawai, H., Park, Y. W., He, X., Goronzy, J. J., & Weyand, C. M. (2007). Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 56(10), 3215-3225.

Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis
Lee, W.- woo, Yang, Z.-Z., Li, G., Weyand, C. A., & Goronzy, J. J. (2007). Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 179(4), 2609-2615.

Immunopathologic aspects of rheumatoid arthritis: who is the conductor and who plays the immunologic instrument?
Weyand, C. M. (2007). Immunopathologic aspects of rheumatoid arthritis: who is the conductor and who plays the immunologic instrument?. journal of rheumatology. Supplement, 79, 9-14.

The diagnosis of giant cell arteritis.
Melson, M. R., Weyand, C. M., Newman, N. J., & Biousse, V. (2007). The diagnosis of giant cell arteritis. Reviews in neurological diseases, 4(3), 128-142.

Aging and T-cell diversity
Goronzy, J. J., Lee, W.- woo, & Weyand, C. M. (2007). Aging and T-cell diversity. EXPERIMENTAL GERONTOLOGY, 42(5), 400-406.

Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis - A randomized trial
Hoffman, G. S., Cid, M. C., Rendt-Zagar, K. E., Merkel, P. A., Weyand, C. M., & Rahman, M. U. (2007). Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis - A randomized trial. ANNALS OF INTERNAL MEDICINE, 146(9), 621-630.

Functional profile of activated dendritic cells in unstable atherosclerotic plaque
Erbel, C., Sato, K., Meyer, F. B., Kopecky, S. L., Frye, R. L., & Weyand, C. M. (2007). Functional profile of activated dendritic cells in unstable atherosclerotic plaque. BASIC RESEARCH IN CARDIOLOGY, 102(2), 123-132.

Occurrence of giant cell arteritis...suddenly.
Younge, B. R., Weyand, C. M., & Goronzy, J. J. (2007). Occurrence of giant cell arteritis...suddenly. Transactions of the American Ophthalmological Society, 105, 141-144.

Immune-mediated mechanisms in atherosclerosis: Prevention and treatment of clinical manifestations
Niessner, A., Goronzy, J. J., & Weyand, C. M. (2007). Immune-mediated mechanisms in atherosclerosis: Prevention and treatment of clinical manifestations. CURRENT PHARMACEUTICAL DESIGN, 13(36), 3701-3710.

Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha
Niessner, A., Sato, K., Chaikof, E. L., Colmegna, I., Goronzy, J. J., & Weyand, C. M. (2006). Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. CIRCULATION, 114(23), 2482-2489.

Siravastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo
Niessner, A., Steiner, S., Speidl, W. S., Pleiner, J., Seidinger, D., & Wojta, J. (2006). Siravastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo. ATHEROSCLEROSIS, 189(2), 408-413.

Treatment of chronic inflammatory diseases with biologic agents: Opportunities and risks for the elderly
Diaz-Borjon, A., Weyand, C. M., & Goronzy, J. J. (2006). Treatment of chronic inflammatory diseases with biologic agents: Opportunities and risks for the elderly. EXPERIMENTAL GERONTOLOGY, 41(12), 1250-1255.

Immunosuppression in atherosclerosis mobilizing the opposition within
Goronzy, J. J., & Weyand, C. M. (2006). Immunosuppression in atherosclerosis mobilizing the opposition within. CIRCULATION, 114(18), 1901-1904.

Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids - A double-blind, placebo-controlled, randomized prospective clinical trial
Mazlumzadeh, M., Hunder, G. G., Easley, K. A., Calamia, K. T., Matteson, E. L., & Goronzy, J. J. (2006). Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids - A double-blind, placebo-controlled, randomized prospective clinical trial. ARTHRITIS AND RHEUMATISM, 54(10), 3310-3318.

Surgical pathology of noninfectious ascending aortitis: A study of 45 cases with emphasis on an isolated variant
Miller, D. V., Isotalo, P. A., Weyand, C. M., Edwards, W. D., Aubry, M.-C., & Tazelaar, H. D. (2006). Surgical pathology of noninfectious ascending aortitis: A study of 45 cases with emphasis on an isolated variant. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 30(9), 1150-1158.

Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis
Turesson, C., Schaid, D. J., Weyand, C. M., Jacobsson, L. T., Goronzy, J. J., & Matteson, E. L. (2006). Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 54(9), 2776-2783.

Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors
Henel, G., Singh, K., Cui, D., Pryshchep, S., Lee, W.- woo, & Goronzy, J. J. (2006). Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors. BLOOD, 107(11), 4449-4457.

T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome
Pryshchep, S., Sato, K., Goronzy, J. J., & Weyand, C. M. (2006). T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. CIRCULATION RESEARCH, 98(9), 1168-1176.

Pathomechanisms in rheumatoid arthritis - time for a string theory?
Weyand, C. M., & Goronzy, J. J. (2006). Pathomechanisms in rheumatoid arthritis - time for a string theory?. JOURNAL OF CLINICAL INVESTIGATION, 116(4), 869-871.

T-cell-targeted therapies in rheumatoid arthritis
Weyand, C. M., & Goronzy, J. J. (2006). T-cell-targeted therapies in rheumatoid arthritis. NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2(4), 201-210.

Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque
Zhang, X. Y., Niessner, A., Nakajima, T., Ma-Krupa, W., Kopecky, S. L., & Weyand, C. M. (2006). Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. CIRCULATION RESEARCH, 98(4), 524-531.

Telomeres, immune aging and autoimmunity
Goronzy, J. J., Fujii, H., & Weyand, C. M. (2006). Telomeres, immune aging and autoimmunity. EXPERIMENTAL GERONTOLOGY, 41(3), 246-251.

Lymphoma in rheumatoid arthritis: An immune system set up for failure
Weyand, C. M., Goronzy, J. J., & Kurtin, P. J. (2006). Lymphoma in rheumatoid arthritis: An immune system set up for failure. ARTHRITIS AND RHEUMATISM, 54(3), 685-689.

TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque
Sato, K., Niessner, A., Kopecky, S. L., Frye, R. L., Goronzy, J. J., & Weyand, C. M. (2006). TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. JOURNAL OF EXPERIMENTAL MEDICINE, 203(1), 239-250.

Tissue trafficking patterns of effector memory CD4+T cells in rheumatoid arthritis
Zhang, X. Y., Nakajima, T., Goronzy, J. J., & Weyand, C. M. (2005). Tissue trafficking patterns of effector memory CD4+T cells in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(12), 3839-3849.

Fractalkine receptor polymorphisms V249I and T280M as genetic risk factors for restenosis
Niessner, A., Marculescu, R., Kvakan, H., Haschemi, A., Endler, G., & Huber, K. (2005). Fractalkine receptor polymorphisms V249I and T280M as genetic risk factors for restenosis. THROMBOSIS AND HAEMOSTASIS, 94(6), 1251-1256.

BLyS and APRIL in rheumatoid arthritis
Seyler, T. M., Park, Y. W., Takemura, S., Bram, R. J., Kurtin, P. J., & Weyand, C. M. (2005). BLyS and APRIL in rheumatoid arthritis. JOURNAL OF CLINICAL INVESTIGATION, 115(11), 3083-3092.

T cell development and receptor diversity during aging
Goronzy, J. J., & Weyand, C. M. (2005). T cell development and receptor diversity during aging. CURRENT OPINION IN IMMUNOLOGY, 17(5), 468-475.

Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis
Bryl, E., Vallejo, A. N., Matteson, E. L., Witkowski, J. M., Weyand, C. M., & Goronzy, J. J. (2005). Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(10), 2996-3003.

Lipopolysaccharide, CD14 and Toll-like receptors: an emerging link between innate immunity and atherosclerotic disease.
Shimada, K., Daida, H., Ma-Krupa, W., Goronzy, J. J., & Weyand, C. M. (2005). Lipopolysaccharide, CD14 and Toll-like receptors: an emerging link between innate immunity and atherosclerotic disease. Future cardiology, 1(5), 657-674.

Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells
Xu, J., Vallejo, A. N., Jiang, Y., Weyand, C. M., & Goronzy, J. J. (2005). Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(25), 24277-24285.

B cells as a therapeutic target in autoimmune diseases
Park, Y. W., Pryshchep, S., Seyler, T. M., Goronzy, J. J., & Weyand, C. M. (2005). B cells as a therapeutic target in autoimmune diseases. EXPERT OPINION ON THERAPEUTIC TARGETS, 9(3), 431-445.

B cells in rheumatoid synovitis
Weyand, C. M., Seyler, T., & Goronzy, J. J. (2005). B cells in rheumatoid synovitis. ARTHRITIS RESEARCH & THERAPY, 7, S9-S12.

The influence of age on T cell generation and TCR diversity
Naylor, K., Li, G. J., Vallejo, A. N., Lee, W. W., Koetz, K., & Goronzy, J. J. (2005). The influence of age on T cell generation and TCR diversity. JOURNAL OF IMMUNOLOGY, 174(11), 7446-7452.

Cell-based immunotherapy with suppressor CD8(+) T cells in rheumatoid arthritis
Davila, E., Kang, Y. M., Park, Y. W., Sawai, H., He, X. W., & Weyand, C. M. (2005). Cell-based immunotherapy with suppressor CD8(+) T cells in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 174(11), 7292-7301.

Opposite effects of CX3CRI receptor polymorphisms V2491 and T280M on the development of acute coronary syndrome - A possible implication of fractalkine in inflammatory activation
Niessner, A., Marculescu, R., Haschemi, A., Endler, G., Zorn, G., & Huber, K. (2005). Opposite effects of CX3CRI receptor polymorphisms V2491 and T280M on the development of acute coronary syndrome - A possible implication of fractalkine in inflammatory activation. THROMBOSIS AND HAEMOSTASIS, 93(5), 949-954.

T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis
Sawai, H., Park, Y. W., Roberson, J., Imai, T., Goronzy, J. J., & Weyand, C. A. (2005). T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(5), 1392-1401.

Toll-like receptors in giant cell arteritis
Wei, M. K., Kwan, M., Goronzy, J. J., & Weyand, C. M. (2005). Toll-like receptors in giant cell arteritis. CLINICAL IMMUNOLOGY, 115(1), 38-46.

Rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2005). Rheumatoid arthritis. IMMUNOLOGICAL REVIEWS, 204, 55-73.

Vascular dendritic cells in giant cell arteritis
Weyand, C. M., Ma-Krupa, W., Pryshchep, O., Groschel, S., Bernardino, R., & Goronzy, J. J. (2005). Vascular dendritic cells in giant cell arteritis. HUMAN IMMUNOLOGY: PATIENT-BASED RESEARCH, 1062, 195-208.

Costimulatory pathways in rheumatoid synovitis and T-cell senescence
Goronzy, J. J., Henel, G., Sawai, H., Singh, K., Lee, E. B., & Weyand, C. M. (2005). Costimulatory pathways in rheumatoid synovitis and T-cell senescence. HUMAN IMMUNOLOGY: PATIENT-BASED RESEARCH, 1062, 182-194.

Increased CD4+ T cell infiltrates in rheumatoid arthritis-associated interstitial pneumonitis compared with idiopathic interstitial pneumonitis
Turesson, C., Matteson, E. L., Colby, T. V., Vuk-Pavlovic, Z., Vassallo, R., & Limper, A. H. (2005). Increased CD4+ T cell infiltrates in rheumatoid arthritis-associated interstitial pneumonitis compared with idiopathic interstitial pneumonitis. ARTHRITIS AND RHEUMATISM, 52(1), 73-79.

The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis
Turesson, C., Schaid, D. J., Weyand, C. M., Jacobsson, L. Th., Goronzy, J. J., & Matteson, E. L. (2005). The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY, 7(6), R1386-R1393.

Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study
Warrington, K. J., Kent, P. D., Frye, R. L., Lymp, J. F., Kopecky, S. L., & Weyand, C. M. (2005). Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. ARTHRITIS RESEARCH & THERAPY, 7(5), R984-R991.

Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis
Park, Y. W., Kang, Y. M., Butterfield, J., Detmar, M., Goronzy, J. J., & Weyand, C. M. (2004). Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis. AMERICAN JOURNAL OF PATHOLOGY, 165(6), 2087-2098.

Genetics of rheumatoid arthritis: Is there a pattern predicting extraarticular manifestations?
Turesson, C., Weyand, C. M., & Matteson, E. L. (2004). Genetics of rheumatoid arthritis: Is there a pattern predicting extraarticular manifestations?. ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 51(5), 853-863.

Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms
Snyder, M. R., Nakajima, T., Leibson, P. J., Weyand, C. M., & Goronzy, J. J. (2004). Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms. JOURNAL OF IMMUNOLOGY, 173(6), 3725-3731.

VEGF gene polymorphisms and susceptibility to rheumatoid arthritis
Han, S. W., Kim, G. W., Seo, J. S., Kim, S. J., Sa, K. H., & Kang, Y. M. (2004). VEGF gene polymorphisms and susceptibility to rheumatoid arthritis. RHEUMATOLOGY, 43(9), 1173-1177.

Stem cell aging and autoimmunity in rheumatoid arthritis
Weyand, C. M., & Goronzy, J. Rj. (2004). Stem cell aging and autoimmunity in rheumatoid arthritis. TRENDS IN MOLECULAR MEDICINE, 10(9), 426-433.

Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription
LEWIS, D. E., Merched-Sauvage, M., Goronzy, J. J., Weyand, C. M., & Vallejo, A. N. (2004). Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(28), 29130-29138.

Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis
Braun, A., Takemura, S., Vallejo, A. N., Goronzy, J. J., & Weyand, C. M. (2004). Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 50(7), 2140-2150.

T-cell regulation in rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2004). T-cell regulation in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY, 16(3), 212-217.

How aggressive should initial therapy for rheumatoid arthritis be? Factors associated with response to 'non-aggressive' DMARD treatment and perspective from a 2-yr open label trial
Matteson, E. L., Weyand, C. M., Fulbright, J. W., Christianson, T. Jh., McClelland, R. L., & Goronzy, J. J. (2004). How aggressive should initial therapy for rheumatoid arthritis be? Factors associated with response to 'non-aggressive' DMARD treatment and perspective from a 2-yr open label trial. RHEUMATOLOGY, 43(5), 619-625.

T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection
Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (2004). T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection. TRENDS IN MOLECULAR MEDICINE, 10(3), 119-124.

Biology of T lymphocytes
Vallejo, A. N., Davila, E., Weyand, C. M., & Goronzy, J. J. (2004). Biology of T lymphocytes. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 30(1), 135-?.

Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis
Ma-Krupa, W., Jeon, M. S., Spoerl, S., Tedder, T. E., Goronzy, J. J., & Weyand, C. M. (2004). Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. JOURNAL OF EXPERIMENTAL MEDICINE, 199(2), 173-183.

HLA-DRB1 haplotype did not affect the medium-term results of total knee arthroplasty in patients with rheumatoid arthritis.
Takemura, S., Toda, Y., Goronzy, J. J., Weyand, C. M., Ogawa, R., & Iida, H. (2004). HLA-DRB1 haplotype did not affect the medium-term results of total knee arthroplasty in patients with rheumatoid arthritis. Modern rheumatology , 14(1), 37-42.

The double life of NK receptors: stimulation or co-stimulation?
Snyder, M. R., Weyand, C. M., & Goronzy, J. J. (2004). The double life of NK receptors: stimulation or co-stimulation?. TRENDS IN IMMUNOLOGY, 25(1), 25-32.

Immunopathways in giant cell arteritis and polymyalgia rheumatica
Weyand, C. M., Ma-Krupa, W., & Goronzy, J. J. (2004). Immunopathways in giant cell arteritis and polymyalgia rheumatica. AUTOIMMUNITY REVIEWS, 3(1), 46-53.

Prognostic markers of radiographic progression in early rheumatoid arthritis
Goronzy, J. J., Matteson, E. L., Fulbright, J. W., Warrington, K. J., Chang-Miller, A., & Weyand, C. M. (2004). Prognostic markers of radiographic progression in early rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 50(1), 43-54.

Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages
Schonland, S. O., Lopez, C., Widmann, T., Zimmer, J., Bryl, E., & Weyand, C. M. (2003). Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100(23), 13471-13476.

Giant-cell arteritis and polymyalgia rheumatica
Weyand, C. M., & Goronzy, J. J. (2003). Giant-cell arteritis and polymyalgia rheumatica. ANNALS OF INTERNAL MEDICINE, 139(6), 505-515.

Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction
Vallejo, A. N., Yang, H. Y., Klimiuk, P. A., Weyand, C. M., & Goronzy, J. J. (2003). Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction. JOURNAL OF IMMUNOLOGY, 171(4), 1732-1740.

Homeostatic control of T-cell generation in neonates
Schonland, S. O., Zimmer, J. K., Lopez-Benitez, C. M., Widmann, T., Ramin, K. D., & Weyand, C. M. (2003). Homeostatic control of T-cell generation in neonates. BLOOD, 102(4), 1428-1434.

Immunosenescence, autoimmunity, and rheumatoid arthritis
Weyand, C. M., Fulbright, J. W., & Goronzy, J. J. (2003). Immunosenescence, autoimmunity, and rheumatoid arthritis. EXPERIMENTAL GERONTOLOGY, 38(8), 833-841.

De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes
Nakajima, T., Goek, O., Zhang, X. Y., Kopecky, S. L., Frye, R. L., & Weyand, C. M. (2003). De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. CIRCULATION RESEARCH, 93(2), 106-113.

Medium- and large-vessel vasculitis.
Weyand, C. M., & Goronzy, J. J. (2003). Medium- and large-vessel vasculitis. New England journal of medicine, 349(2), 160-169.

The power of the third dimension: tissue architecture and autoimmunity in rheumatoid arthritis
Weyand, C. M., Kang, Y. M., Kurtin, P. J., & Goronzy, J. J. (2003). The power of the third dimension: tissue architecture and autoimmunity in rheumatoid arthritis. CURRENT OPINION IN RHEUMATOLOGY, 15(3), 259-266.

CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation
Warrington, K. J., Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (2003). CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation. BLOOD, 101(9), 3543-3549.

Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4(+) T cells
Snyder, M. R., Lucas, M., Vivier, E., Weyand, C. M., & Goronzy, J. J. (2003). Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4(+) T cells. JOURNAL OF EXPERIMENTAL MEDICINE, 197(4), 437-449.

B cells as a therapeutic target in autoimmune disease
Goronzy, J. J., & Weyand, C. M. (2003). B cells as a therapeutic target in autoimmune disease. ARTHRITIS RESEARCH & THERAPY, 5(3), 131-135.

Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation.
Goronzy, J. J., & Weyand, C. M. (2003). Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation. Arthritis research & therapy, 5(5), 225-234.

Ectopic germinal center formation in rheumatoid synovitis
Weyand, C. M., & Goronzy, J. J. (2003). Ectopic germinal center formation in rheumatoid synovitis. IMMUNE MECHANISMS AND DISEASE, 987, 140-149.

Molecular basis for the loss of CD28 expression in senescent T cells
Vallejo, A. N., Bryl, E., Klarskov, K., Naylor, S., Weyand, C. M., & Goronzy, J. J. (2002). Molecular basis for the loss of CD28 expression in senescent T cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(49), 46940-46949.

Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis
Krupa, W. M., Dewan, M., Jeon, M. S., Kurtin, P. J., Younge, B. R., & Weyand, C. M. (2002). Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis. AMERICAN JOURNAL OF PATHOLOGY, 161(5), 1815-1823.

Reactive nitrogen intermediates in giant cell arteritis - Selective nitration of neocapillaries
Borkowski, A., Younge, B. R., Szweda, L., Mock, B., Bjornsson, J., & Weyand, C. M. (2002). Reactive nitrogen intermediates in giant cell arteritis - Selective nitration of neocapillaries. AMERICAN JOURNAL OF PATHOLOGY, 161(1), 115-123.

Premature immunosenescence in rheumatoid arthritis.
Weyand, C. M., & Goronzy, J. J. (2002). Premature immunosenescence in rheumatoid arthritis. journal of rheumatology, 29(6), 1141-1146.

CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis
Kang, Y. M., Zhang, X. Y., Wagner, U. G., Yang, H. Y., Beckenbaugh, R. D., & Weyand, C. M. (2002). CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis. JOURNAL OF EXPERIMENTAL MEDICINE, 195(10), 1325-1336.

Human leukocyte antigen class II immune response genes, female gender, and cigarette smoking as risk and modulating factors in abdominal aortic aneurysms
Rasmussen, T. E., Hallett, J. W., Tazelaar, H. D., Miller, V. M., Schulte, S., & Weyand, C. M. (2002). Human leukocyte antigen class II immune response genes, female gender, and cigarette smoking as risk and modulating factors in abdominal aortic aneurysms. JOURNAL OF VASCULAR SURGERY, 35(5), 988-993.

Formation of the killer Ig-like receptor repertoire on CD4(+)CD28(null) T cells
Snyder, M. R., Muegge, L. O., Offord, C., O'Fallon, W. M., Bajzer, Z., & Goronzy, J. J. (2002). Formation of the killer Ig-like receptor repertoire on CD4(+)CD28(null) T cells. JOURNAL OF IMMUNOLOGY, 168(8), 3839-3846.

T-cell-mediated lysis of endothelial cells in acute coronary syndromes
Nakajima, T., Schulte, S., Warrington, K. J., Kopecky, S. L., Frye, R. L., & Weyand, C. M. (2002). T-cell-mediated lysis of endothelial cells in acute coronary syndromes. CIRCULATION, 105(5), 570-575.

Therapeutic effects of acetylsalicylic acid in giant cell arteritis
Weyand, C. M., Kaiser, M., Yang, H. Y., Younge, B., & Goronzy, J. J. (2002). Therapeutic effects of acetylsalicylic acid in giant cell arteritis. ARTHRITIS AND RHEUMATISM, 46(2), 457-466.

Bi-directional modulation of T cell-dependent antibody production by prostaglandin E-2
He, X. W., Weyand, C. M., Goronzy, J. J., Zhong, W. Y., & Stuart, J. M. (2002). Bi-directional modulation of T cell-dependent antibody production by prostaglandin E-2. INTERNATIONAL IMMUNOLOGY, 14(1), 69-77.

Pathogenic mechanisms in giant cell arteritis.
Weyand, C. M., & Goronzy, J. J. (2002). Pathogenic mechanisms in giant cell arteritis. Cleveland Clinic journal of medicine, 69, SII28-32.

Cytokines in giant-cell arteritis.
Goronzy, J. J., & Weyand, C. M. (2002). Cytokines in giant-cell arteritis. Cleveland Clinic journal of medicine, 69, SII91-4.

Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
Goronzy, J. J., Fulbright, J. W., Crowson, C. S., Poland, G. A., O'Fallon, W. M., & Weyand, C. M. (2001). Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. JOURNAL OF VIROLOGY, 75(24), 12182-12187.

T cell activation in rheumatoid synovium is B cell dependent
Takemura, S., Klimiuk, P. A., Braun, A., Goronzy, J. J., & Weyand, C. M. (2001). T cell activation in rheumatoid synovium is B cell dependent. JOURNAL OF IMMUNOLOGY, 167(8), 4710-4718.

T-cell immunity in acute coronary syndromes
Weyand, C. M., Goronzy, J. J., Liuzzo, G., Kopecky, S. L., Holmes, D. R., & Frye, R. L. (2001). T-cell immunity in acute coronary syndromes. MAYO CLINIC PROCEEDINGS, 76(10), 1011-1020.

Down-regulation of CD28 expression by TNF-alpha
Bryl, E., Vallejo, A. N., Weyand, C. M., & Goronzy, J. J. (2001). Down-regulation of CD28 expression by TNF-alpha. JOURNAL OF IMMUNOLOGY, 167(6), 3231-3238.

Ectopic lymphoid organogenesis - A fast track for autoimmunity
Weyand, C. M., Kurtin, P. J., & Goronzy, J. J. (2001). Ectopic lymphoid organogenesis - A fast track for autoimmunity. AMERICAN JOURNAL OF PATHOLOGY, 159(3), 787-793.

Lymphoid neogenesis in rheumatoid synovitis
Takemura, S., Braun, A., Crowson, C., Kurtin, P. J., Cofield, R. H., & Weyand, C. M. (2001). Lymphoid neogenesis in rheumatoid synovitis. JOURNAL OF IMMUNOLOGY, 167(2), 1072-1080.

Genetic similarity in inflammatory and degenerative abdominal aortic aneurysms: A study of human leukocyte antigen class II disease risk genes
Rasmussen, T. E., Hallett, J. W., Schulte, S., Harmsen, W. S., O'Fallon, W. M., & Weyand, C. M. (2001). Genetic similarity in inflammatory and degenerative abdominal aortic aneurysms: A study of human leukocyte antigen class II disease risk genes. JOURNAL OF VASCULAR SURGERY, 34(1), 84-88.

Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis
Yen, J. H., Moore, B. E., Nakajima, T., SCHOLL, D., Schaid, D. J., & Goronzy, J. J. (2001). Major histocompatibility complex class I-recognizing receptors are disease risk genes in rheumatoid arthritis. JOURNAL OF EXPERIMENTAL MEDICINE, 193(10), 1159-1167.

Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis
Goronzy, J. J., & Weyand, C. M. (2001). Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis. TRENDS IN IMMUNOLOGY, 22(5), 251-255.

Molecular fingerprint of interferon-gamma signaling in unstable angina
Liuzzo, G., Vallejo, A. N., Kopecky, S. L., Frye, R. L., Holmes, D. R., & Weyand, C. M. (2001). Molecular fingerprint of interferon-gamma signaling in unstable angina. CIRCULATION, 103(11), 1509-1514.

Functional disruption of the CD28 gene transcriptional initiator in senescent T cells
Vallejo, A. N., Weyand, C. M., & Goronzy, J. Y. (2001). Functional disruption of the CD28 gene transcriptional initiator in senescent T cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(4), 2565-2570.

T cell homeostasis and autoreactivity in rheumatoid arthritis.
Goronzy, J. J., & Weyand, C. M. (2001). T cell homeostasis and autoreactivity in rheumatoid arthritis. Current directions in autoimmunity, 3, 112-132.

Lymphoid microstructures in rheumatoid synovitis.
Weyand, C. M., Braun, A., Takemura, S., & Goronzy, J. J. (2001). Lymphoid microstructures in rheumatoid synovitis. Current directions in autoimmunity, 3, 168-187.

CD4+,CD28-T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems
Warrington, K. J., Takemura, S., Goronzy, J. J., & Weyand, C. M. (2001). CD4+,CD28-T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems. ARTHRITIS AND RHEUMATISM, 44(1), 13-20.

Clonality and longevity of CD4(+)CD28(null) T cells are associated with defects in apoptotic pathways
Vallejo, A. N., Schirmer, M., Weyand, C. M., & Goronzy, J. J. (2000). Clonality and longevity of CD4(+)CD28(null) T cells are associated with defects in apoptotic pathways. JOURNAL OF IMMUNOLOGY, 165(11), 6301-6307.

Pathogenic principles in giant cell arteritis
Weyand, C. M., & Goronzy, J. J. (2000). Pathogenic principles in giant cell arteritis. INTERNATIONAL JOURNAL OF CARDIOLOGY, 75, S9-S15.

T cell homeostasis in patients with rheumatoid arthritis
Koetz, K., Bryl, E., Spickschen, K., O'Fallon, W. M., Goronzy, J. J., & Weyand, C. M. (2000). T cell homeostasis in patients with rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 97(16), 9203-?.

Killer cell activating receptors function as costimulatory molecules on CD4(+)CD28(null) T cells clonally expanded in rheumatoid arthritis
NAMEKAWA, T., Snyder, M. R., Yen, J. H., Goehring, B. E., Leibson, P. J., & Goronzy, J. J. (2000). Killer cell activating receptors function as costimulatory molecules on CD4(+)CD28(null) T cells clonally expanded in rheumatoid arthritis. JOURNAL OF IMMUNOLOGY, 165(2), 1138-1145.

Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes
Liuzzo, G., Goronzy, J. J., Yang, H. Y., Kopecky, S. L., Holmes, D. R., & Weyand, C. M. (2000). Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. CIRCULATION, 101(25), 2883-2888.

New insights into the pathogenesis of rheumatoid arthritis
Weyand, C. M. (2000). New insights into the pathogenesis of rheumatoid arthritis. RHEUMATOLOGY, 39, 3-8.

[Clinical and genetic heterogeneity of rheumatoid arthritis].
Klimiuk, P. A., Weyand, C. M., Sierakowski, S., & Goronzy, J. J. (2000). [Clinical and genetic heterogeneity of rheumatoid arthritis]. Post?py higieny i medycyny doswiadczalnej, 54(6), 845-853.

Cell-cell interactions in synovitis - Interactions between T cells and B cells in rheumatoid arthritis
Weyand, C. M., Goronzy, J. J., Takemura, S., & Kurtin, P. J. (2000). Cell-cell interactions in synovitis - Interactions between T cells and B cells in rheumatoid arthritis. ARTHRITIS RESEARCH, 2(6), 457-463.

The role of T cells in rheumatoid arthritis.
Weyand, C. M., Bryl, E., & Goronzy, J. J. (2000). The role of T cells in rheumatoid arthritis. Archivum immunologiae et therapiae experimentalis, 48(5), 429-435.

Association of MHC and rheumatoid arthritis HLA polymorphisms in phenotypic variants of rheumatoid arthritis
Weyand, C. M., & Goronzy, J. J. (2000). Association of MHC and rheumatoid arthritis HLA polymorphisms in phenotypic variants of rheumatoid arthritis. ARTHRITIS RESEARCH, 2(3), 212-216.

IL-16 as an anti-inflammatory cytokine in rheumatoid synovitis
Klimiuk, P. A., Goronzy, J. J., & Weyand, C. M. (1999). IL-16 as an anti-inflammatory cytokine in rheumatoid synovitis. JOURNAL OF IMMUNOLOGY, 162(7), 4293-4299.

Heterogeneity of rheumatoid arthritis: from phenotypes to genotypes
Weyand, C. M., Klimiuk, P. A., & Goronzy, J. J. (1998). Heterogeneity of rheumatoid arthritis: from phenotypes to genotypes. SPRINGER SEMINARS IN IMMUNOPATHOLOGY, 20(1-2), 5-22.

Tissue cytokine patterns distinguish variants of rheumatoid synovitis
Klimiuk, P. A., Goronzy, J. J., Bjornsson, J., Beckenbaugh, R. D., & Weyand, C. M. (1997). Tissue cytokine patterns distinguish variants of rheumatoid synovitis. AMERICAN JOURNAL OF PATHOLOGY, 151(5), 1311-1319.

TRIGGERING OF LYMPHOCYTES-T VIA EITHER T3-TI OR T11 SURFACE-STRUCTURES OPENS A VOLTAGE-INSENSITIVE PLASMA-MEMBRANE CALCIUM-PERMEABLE CHANNEL - REQUIREMENT FOR INTERLEUKIN-2 GENE-FUNCTION
Gardner, P., Alcover, A., Kuno, M., Moingeon, P., Weyand, C. M., & REINHERZ, E. L. (1989). TRIGGERING OF LYMPHOCYTES-T VIA EITHER T3-TI OR T11 SURFACE-STRUCTURES OPENS A VOLTAGE-INSENSITIVE PLASMA-MEMBRANE CALCIUM-PERMEABLE CHANNEL - REQUIREMENT FOR INTERLEUKIN-2 GENE-FUNCTION. JOURNAL OF BIOLOGICAL CHEMISTRY, 264(2), 1068-1076.