David J. Wong, M.D., Ph.D.

Dermatologist, General dermatologist

Clinical Associate Professor, Dermatology

General Dermatology Clinic

  • 450 Broadway Street
  • Redwood City, CA 94063
  • Phone: 650-723-6316
Learn More About the Clinic Getting Here Make An Appointment

General Dermatology Clinic in Redwood City

  • 450 Broadway Street
  • Redwood City, CA 94063
  • Phone: 650-723-6316
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Internship: Santa Clara Valley Medical Center (2003) CA

Board Certification: Dermatology, American Board of Dermatology (2006)

Residency: Stanford University Medical Center (2006) CA

M.D., University of Washington (2002)

Ph.D., Fred Hutchinson Cancer Center, Molecular and Cellular Biology (2000)

B.S., Brown University, Biochemistry (1994)

Medical Education: University of Washington School of Medicine (2002) WA

Professional Education: University of Washington (2000) WA

Residency, Stanford University, Dermatology (2006)

Honors & Awards

K08 Clinical Scientist Development Award, NIH (2009-2010)

Young Investigator Award, American Academy of Dermatology (2008)

Research Career Development Award, Dermatology Foundation (2006-2009)

Research Fellowship, Dermatology Foundation (2005-2006)

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
Hung, T., Wang, Y., Lin, M. F., Koegel, A. K., Kotake, Y., & Chang, H. Y. (2011). Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. NATURE GENETICS, 43(7), 621-U196.

Stemness, cancer and cancer stem cells
Wong, D. J., Segal, E., & Chang, H. Y. (2008). Stemness, cancer and cancer stem cells. CELL CYCLE, 7(23), 3622-3624.

Deletional tolerance mediated by extrathymic Aire-expressing cells
Gardner, J. M., DeVoss, J. J., Friedman, R. S., Wong, D. J., Tan, Y. X., & Anderson, M. S. (2008). Deletional tolerance mediated by extrathymic Aire-expressing cells. SCIENCE, 321(5890), 843-847.

Module map of stem cell genes guides creation of epithelial cancer stem cells
Wong, D. J., Liu, H., Ridky, T. W., Cassarino, D., Segal, E., & Chang, H. Y. (2008). Module map of stem cell genes guides creation of epithelial cancer stem cells. CELL STEM CELL, 2(4), 333-344.

Revealing targeted therapy for human cancer by gene module maps
Wong, D. J., Nuyten, D. Sa., Regev, A., Lin, M., Adler, A. S., & Chang, H. Y. (2008). Revealing targeted therapy for human cancer by gene module maps. CANCER RESEARCH, 68(2), 369-378.

Learning more from microarrays: Insights from modules and networks
Wong, D. J., & Chang, H. Y. (2005). Learning more from microarrays: Insights from modules and networks. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 125(2), 175-182.

A Molecular Signature for Purified Definitive Endoderm Guides Differentiation and Isolation of Endoderm from Mouse and Human Embryonic Stem Cells
Wang, P., McKnight, K. D., Wong, D. J., Rodriguez, R. T., Sugiyama, T., & Kim, S. K. (2012). A Molecular Signature for Purified Definitive Endoderm Guides Differentiation and Isolation of Endoderm from Mouse and Human Embryonic Stem Cells. STEM CELLS AND DEVELOPMENT, 21(12), 2273-2287.

Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases
Wong, D., Kea, B., Pesich, R., Higgs, B. W., Zhu, W., & Fiorentino, D. (2012). Interferon and Biologic Signatures in Dermatomyositis Skin: Specificity and Heterogeneity across Diseases. PLOS ONE, 7(1).

Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia
Ridky, T. W., Chow, J. M., Wong, D. J., & Khavari, P. A. (2010). Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia. NATURE MEDICINE, 16(12), 1450-U137.

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
Gupta, R. A., Shah, N., Wang, K. C., Kim, J., Horlings, H. M., & Chang, H. Y. (2010). Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. NATURE, 464(7291), 1071-U148.

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
Chan, K. S., Espinosa, I., Chao, M., Wong, D., Ailles, L., & Weissman, I. L. (2009). Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(33), 14016-14021.

CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression
Adler, A. S., Littlepage, L. E., Lin, M., Kawahara, T. La., Wong, D. J., & Chang, H. Y. (2008). CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression. CANCER RESEARCH, 68(2), 506-515.

p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium
Wong, D. J., Paulson, T. G., Prevo, L. J., Galipeau, P. C., Longton, G., & Reid, B. J. (2001). p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium. CANCER RESEARCH, 61(22), 8284-8289.

Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M-0 growth arrest
Wong, D. J., Foster, S. A., Galloway, D. A., & Reid, B. J. (1999). Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from M-0 growth arrest. MOLECULAR AND CELLULAR BIOLOGY, 19(8), 5642-5651.

Evolution of neoplastic cell lineages in Barrett oesophagus
Barrett, M. T., Sanchez, C. A., Prevo, L. J., Wong, D. J., Galipeau, P. C., & Reid, B. J. (1999). Evolution of neoplastic cell lineages in Barrett oesophagus. NATURE GENETICS, 22(1), 106-109.

p16(INK4a) expression is frequently decreased and associated with 9p21 loss of heterozygosity in sporadic melanoma
FUNK, J. O., Schiller, P. I., Barrett, M. T., Wong, D. J., Kind, P., & SANDER, C. A. (1998). p16(INK4a) expression is frequently decreased and associated with 9p21 loss of heterozygosity in sporadic melanoma. JOURNAL OF CUTANEOUS PATHOLOGY, 25(6), 291-296.

Inactivation of p16 in human mammary epithelial cells by CpG island methylation
Foster, S. A., Wong, D. J., Barrett, M. T., & Galloway, D. A. (1998). Inactivation of p16 in human mammary epithelial cells by CpG island methylation. MOLECULAR AND CELLULAR BIOLOGY, 18(4), 1793-1801.

Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes
Trask, B. J., Friedman, C., Martin-Gallardo, A., Rowen, L., Akinbami, C., & van den Engh, G. (1998). Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes. HUMAN MOLECULAR GENETICS, 7(1), 13-26.

P16(INK4 alpha) promoter is hypermethylated at a high frequency in esophageal adenocarcinomas
Wong, D. J., Barrett, M. T., Stoger, R., Emond, M. J., & Reid, B. J. (1997). P16(INK4 alpha) promoter is hypermethylated at a high frequency in esophageal adenocarcinomas. CANCER RESEARCH, 57(13), 2619-2622.

THE FORMATION AND MAINTENANCE OF THE DEFINITIVE ENDODERM LINEAGE IN THE MOUSE - INVOLVEMENT OF HNF3/FORKHEAD PROTEINS
Ang, S. L., Wierda, A., Wong, D., Stevens, K. A., Cascio, S., & Zaret, K. S. (1993). THE FORMATION AND MAINTENANCE OF THE DEFINITIVE ENDODERM LINEAGE IN THE MOUSE - INVOLVEMENT OF HNF3/FORKHEAD PROTEINS. DEVELOPMENT, 119(4), 1301-1315.