Joy Wu

Endocrinologist

Endocrinology Clinic

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-725-8439
Learn More About the Clinic Getting Here Make An Appointment

Osteoporosis and Metabolic Bone Diseases Clinic

  • 300 Pasteur Drive
  • Stanford, CA 94305
  • Phone: 650-723-6961
Learn More About the Clinic Getting Here Make An Appointment

Professional Education

Board Certification: Endocrinology, Diabetes and Metabolism, American Board of Internal Medicine (2006)

Fellowship: Massachusetts General Hospital (2006) MA

Board Certification: Internal Medicine, American Board of Internal Medicine (2004)

Residency: Brigham and Women's Hospital Harvard Medical School (2003) MA

Medical Education: Duke University School of Medicine (2001) NC

MD/PhD, Duke University (2001)

Honors & Awards

Cancer Grant Recipient, The Mary Kay Foundation (2013 - 2015)

NIH Director's New Innovator Award, NIH (2011 - 2016)

Clinical Scientist Program Instructor Development Award, Harvard Stem Cell Institute (2009 - 2011)

Claflin Distinguished Scholar Award, Massachusetts General Hospital (2009 - 2011)

John Haddad Young Investigator Award, Advances in Mineral Metabolism (2008)

Merck Senior Fellow Award, The Endocrine Society (2007)

Young Investigator Award, American Society for Bone and Mineral Research Annual Meeting (2006)

Endocrine Scholars Award, The Endocrine Society (2006)

Alpha Omega Alpha, Duke University School of Medicine (1997)

Phi Beta Kappa, Stanford University (1993)

Marsden Memorial Award in Chemistry, Stanford University (1993)

Teriparatide ( PTH1-34) Treatment Increases Peripheral Hematopoietic Stem Cells in Postmenopausal Women
Yu, E. W., Kumbhani, R., Siwila-Sackman, E., DeLelys, M., Preffer, F. I., & Wu, J. Y. (2014). Teriparatide ( PTH1-34) Treatment Increases Peripheral Hematopoietic Stem Cells in Postmenopausal Women. JOURNAL OF BONE AND MINERAL RESEARCH, 29(6), 1380-1386.

Loss of Gs α Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors.
Sinha, P., Aarnisalo, P., Chubb, R., Ono, N., Fulzele, K., & Wu, J. Y. (2014). Loss of Gs α Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Differential regulation of myeloid leukemias by the bone marrow microenvironment.
Krause, D. S., Fulzele, K., Catic, A., Sun, C. C., Dombkowski, D., & Scadden, D. T. (2013). Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nature medicine, 19(11), 1513-1517.

Myelopoiesis is regulated by osteocytes through Gsa-dependent signaling.
Fulzele, K., Krause, D. S., Panaroni, C., Saini, V., Barry, K. J., & Divieti Pajevic, P. (2013). Myelopoiesis is regulated by osteocytes through Gsa-dependent signaling. Blood, 121(6), 930-939.

G(s)alpha enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice
Wu, J. Y., Aarnisalo, P., Bastepe, M., Sinha, P., Fulzele, K., & Kronenberg, H. M. (2011). G(s)alpha enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice. JOURNAL OF CLINICAL INVESTIGATION, 121(9), 3492-3504.

Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches
Wu, J. Y., Scadden, D. T., & Kronenberg, H. M. (2009). Role of the Osteoblast Lineage in the Bone Marrow Hematopoietic Niches. JOURNAL OF BONE AND MINERAL RESEARCH, 24(5), 759-764.

Osteoblastic regulation of B lymphopoiesis is mediated by G(s)alpha-dependent signaling pathways
Wu, J. Y., Purton, L. E., Rodda, S. J., Chen, M., Weinstein, L. S., & Kronenberg, H. M. (2008). Osteoblastic regulation of B lymphopoiesis is mediated by G(s)alpha-dependent signaling pathways. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(44), 16976-16981.

The PTH-G alpha(s)-Protein Kinase A Cascade Controls alpha NAC Localization To Regulate Bone Mass
Pellicelli, M., Miller, J. A., Arabian, A., Gauthier, C., Akhouayri, O., & St-Arnaud, R. (2014). The PTH-G alpha(s)-Protein Kinase A Cascade Controls alpha NAC Localization To Regulate Bone Mass. MOLECULAR AND CELLULAR BIOLOGY, 34(9), 1622-1633.

Mesenchymal progenitors and the osteoblast lineage in bone marrow hematopoietic niches.
Panaroni, C., Tzeng, Y.-S., Saeed, H., & Wu, J. Y. (2014). Mesenchymal progenitors and the osteoblast lineage in bone marrow hematopoietic niches. Current osteoporosis reports, 12(1), 22-32.

Interactions between B lymphocytes and the osteoblast lineage in bone marrow.
Panaroni, C., & Wu, J. Y. (2013). Interactions between B lymphocytes and the osteoblast lineage in bone marrow. Calcified tissue international, 93(3), 261-268.

Development of the skeleton
Provot, S., Schipani, E., Wu, J. Y., & Kronenberg, H. M. (2013). Development of the skeleton. Osteoporosis, 4th Edition. Academic Press.

Potent constitutive cyclic AMP-generating activity of XL alpha s implicates this imprinted GNAS product in the pathogenesis of McCune-Albright Syndrome and fibrous dysplasia of bone
Mariot, V., Wu, J. Y., Aydin, C., Mantovani, G., Mahon, M. J., & Bastepe, M. (2011). Potent constitutive cyclic AMP-generating activity of XL alpha s implicates this imprinted GNAS product in the pathogenesis of McCune-Albright Syndrome and fibrous dysplasia of bone. BONE, 48(2), 312-320.

The role of bone cells in establishing the hematopoietic stem cell niche
Wu, J. Y., & Kronenberg, H. M. (2011). The role of bone cells in establishing the hematopoietic stem cell niche. Osteoimmunology: Interactions of the Immune and Skeletal Systems (81-99).

Spermatogenesis and the regulation of Ca2+-calmodulin-dependent protein kinase IV localization are not dependent on calspermin
Wu, J. Y., Ribar, T. J., & Means, A. R. (2001). Spermatogenesis and the regulation of Ca2+-calmodulin-dependent protein kinase IV localization are not dependent on calspermin. MOLECULAR AND CELLULAR BIOLOGY, 21(17), 6066-6070.

Female fertility is reduced in mice lacking Ca2+ calmodulin-dependent protein kinase IV
Wu, J. Y., Gonzalez-Robayna, I. J., Richards, J. S., & Means, A. R. (2000). Female fertility is reduced in mice lacking Ca2+ calmodulin-dependent protein kinase IV. ENDOCRINOLOGY, 141(12), 4777-4783.

Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4
Wu, J. Y., Ribar, T. J., Cummings, D. E., Burton, K. A., McKnight, G. S., & Means, A. R. (2000). Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. NATURE GENETICS, 25(4), 448-452.

Ca2+/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix
Wu, J. Y., & Means, A. R. (2000). Ca2+/calmodulin-dependent protein kinase IV is expressed in spermatids and targeted to chromatin and the nuclear matrix. JOURNAL OF BIOLOGICAL CHEMISTRY, 275(11), 7994-7999.