Biography


I am a physician scientist with interests in cardiomyopathies, rare and undiagnosed diseases, therapeutics and genomics. I am a physician with interest and experience treating patients with hypertrophic cardiomyopathy, neuromuscular disease associated cardiomyopathies including adults with Duchenne and Becker muscular dystrophies, myotonic dystrophy, limb girdle muscular dystrophies, inherited dilated cardiomyopathies, advanced heart failure, mechanical circulatory support/LVADs, heart and multiorgan transplant, and competitive athletes with cardiac disease. I am Director of the Stanford Center for Undiagnosed Diseases, a clinical site of the Undiagnosed Diseases Network.. I have extensive translational science efforts, as site PI for ongoing clinical trials for hypertrophic cardiomyopathy and dilated cardiomyopathy and for cardiomyopathy consortia including NONCOMPACT, PPCM and the Precision Medicine Study/DCM Consortium. I am Co-PI of the GREGoR Stanford Site, a research center of the GREGoR Consortium, and Co-PI of the NIH-funded Bioinformatics Center of the Molecular Transducers of Physical Activity Consortium. Our laboratory efforts focus on advancing diagnostic and therapeutic approaches in ultrarare diseases, with a focus on RNA-based diagnostics and therapeutics. I pursue projects and collaborations at the intersection of striated muscle genetics, genomics, therapeutics and clinical investigation.

Professional Summary


Education & Certifications
  • Fellowship: Stanford University Advanced Heart Failure and Transplant Fellowship (2013) CA
  • Fellowship: Stanford University Cardiovascular Medicine Fellowship (2012) CA
  • Residency: Stanford University Internal Medicine Residency (2007) CA
  • Medical Education: Pritzker School of Medicine University of Chicago Registrar (2005) IL
  • Board Certification: American Board of Internal Medicine, Advanced Heart Failure and Transplant Cardiology (2014)
  • Board Certification: American Board of Internal Medicine, Cardiovascular Disease (2012)
  • Bachelor of Arts, Williams College, History and Biology (1998)

Memberships
  • Member, American Heart Association (2012 - Present)
  • Member, American College of Cardiology (2017 - Present)
  • Member, American Society of Human Genetics (2016 - Present)

Administrative Appointments
  • Adult Medical Director, Center for Undiagnosed Diseases at Stanford (2015 - Present)
  • Director, Center for Undiagnosed Diseases at Stanford (2014 - Present)

Publications

Practice Locations


Heart Transplant Program Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A21

Stanford , CA 94305

(650) 723-5468

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Advanced Heart Failure Clinic at Stanford Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 724-4942

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Hypertrophic Cardiomyopathy Center Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 736-7878

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Amyloid Center Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 725-6186

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Stanford Sports Cardiology Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 736-7878

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Mechanical Circulatory Support Program Stanford, CA
Stanford, CA

300 Pasteur Drive , 2nd Floor, Room A260

Stanford , CA 94305

(650) 723-5468

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Center for Inherited Cardiovascular Disease at Stanford Stanford, CA
Stanford, CA

300 Pasteur Drive, Heart Clinic 1, Clinic A21

Stanford , CA 94305

(650) 736-7878

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Patient Reviews

(27 reviews)

I value & trust Dr. Wheeler's advice.
I love the way the care providers work as a team.
Dr Wheeler, RN Trish and RN Marie are exemplary providers in every way.
Dr. Wheeler is excellent.
I am pleased and grateful for Dr. Wheeler's care in every way. Outstanding physician! Consummate professional!!
Dr. Wheeler is excellent. I have immense confidence in him.
Very, very professional. I'm hoping to get him to laugh or even a smile. As a patient with heart problems its feels good to know you can make you dr. laugh or even smile. Yes I like my new dr.
Spent a good amount of time with me.
A++++ world class.
Dr. Wheeler always excellent. Julia Platt - genetics consultant also very good.
Everyone was so professional but in a relaxed and friendly way.
Dr. Matthew Wheeler ALWAYS takes the time to help us understand where I am at in my process and LISTENS to what I am needing to tell him about such a big decision. My confidence in him and Stanford is so very high. I am grateful.
They listened & observed the pain but no solutions they measured the # of low flows but offered no new information - why were we there?
Dr. Wheeler is excellent in all ways.
Good.
Dr. Wheeler is terrific.
Great follow up - Thank you.
Exceptional visit.
Quiet voice. I had to ask him to speak louder several times. Very professional and caring.
I never feel hurried or rushed at my appointments. They are very caring -
Good.
I feel privileged to be under the care of such great doctors and I tell everyone what excellent treatment and receiving
After the visit when I forgot the instructions the care provider wasn't as clear or patient. But that's understandable b/c it was their time.
Great first visit with Dr. Wheeler took plenty of time to review details with me.
Dr. Wheeler is a very competent physician and spent all the time needed to inform me of my available choices.
Always very detailed - spends quality time.
We are impressed with the quality and quantity of time we've had with each doctor and supporting staff. It's something we talk about with our friends and family. I feel like I'm in the best possible hands in the world.

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