George Yang

General surgeon

Professional Education

Medical Education: Northwestern University Feinberg School of Medicine (1994) IL

Residency: Stanford University School of Medicine (2001) CA

Internship: Stanford University School of Medicine (1995) CA

Board Certification: General Surgery, American Board of Surgery (2002)

BA, Northwestern University, biological sciences (1985)

MD, Northwestern Univ Med School, medicine (1994)

PhD, Univ of Illinois Coll of Med, molecular genetics (1993)

Honors & Awards

Resident Research Scholarship, American College of Surgeons (1996-1998)

Faculty Research Fellow, American College of Surgeons (2002-2004)

Wound Care Management Award, American College of Surgeons (2008-2010)

Faculty Scholarship, Robert L and Mary Ellenburg Foundation (2008-2011)

Chair, Publications Committee, Society of University Surgeons (2008-2010)

President, Society of University Surgeons (2012-2013)

Fellow, American Surgical Association (2013-present)

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Hospital & Clinics patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

The angiogenic factor Dell prevents apoptosis of endothelial cells through integrin binding
Wang, Z., Kundu, R. K., Longaker, M. T., Quertermous, T., & Yang, G. P. (2012). The angiogenic factor Dell prevents apoptosis of endothelial cells through integrin binding. SURGERY, 151(2), 296-305.

Unfolded Protein Response Regulation in Keloid Cells
Butler, P. D., Wang, Z., Ly, D. P., Longaker, M. T., Koong, A. C., & Yang, G. P. (2011). Unfolded Protein Response Regulation in Keloid Cells. JOURNAL OF SURGICAL RESEARCH, 167(1), 151-157.

Comparative Healing of Rat Fascia Following Incision with Three Surgical Instruments
Chang, E. I., Carlson, G. A., Vose, J. G., Huang, E. J., & Yang, G. P. (2011). Comparative Healing of Rat Fascia Following Incision with Three Surgical Instruments. JOURNAL OF SURGICAL RESEARCH, 167(1), E47-E54.

Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation
Lahti, J. L., Lui, B. H., Beck, S. E., Lee, S. S., Ly, D. P., & Cochran, J. R. (2011). Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation. FEBS LETTERS, 585(8), 1135-1139.

DOSE-ESCALATION STUDY OF SINGLE-FRACTION STEREOTACTIC BODY RADIOTHERAPY FOR LIVER MALIGNANCIES
Goodman, K. A., Wiegner, E. A., Maturen, K. E., Zhang, Z., Mo, Q., & Koong, A. C. (2010). DOSE-ESCALATION STUDY OF SINGLE-FRACTION STEREOTACTIC BODY RADIOTHERAPY FOR LIVER MALIGNANCIES. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(2), 486-493.

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
Boiko, A. D., Razorenova, O. V., van de Rijn, M., Swetter, S. M., Johnson, D. L., & Weissman, I. L. (2010). Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. NATURE, 466(7302), 133-U155.

Cell Permeant Peptide Analogues of the Small Heat Shock Protein, HSP20, Reduce TGF-beta 1-Induced CTGF Expression in Keloid Fibroblasts
Lopes, L. B., Furnish, E. J., Komalavilas, P., Flynn, C. R., Ashby, P., & Brophy, C. M. (2009). Cell Permeant Peptide Analogues of the Small Heat Shock Protein, HSP20, Reduce TGF-beta 1-Induced CTGF Expression in Keloid Fibroblasts. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 129(3), 590-598.

The Role of Tumor Cell-Derived Connective Tissue Growth Factor (CTGF/CCN2) in Pancreatic Tumor Growth
Bennewith, K. L., Huang, X., Ham, C. M., Graves, E. E., Erler, J. T., & Giaccia, A. J. (2009). The Role of Tumor Cell-Derived Connective Tissue Growth Factor (CTGF/CCN2) in Pancreatic Tumor Growth. CANCER RESEARCH, 69(3), 775-784.

Gemcitabine chemotherapy and single-fraction stereotactic body radiotherapy for locally advanced pancreatic cancer
Schellenberg, D., Goodman, K. A., Lee, F., Chang, S., Kuo, T., & Koong, A. C. (2008). Gemcitabine chemotherapy and single-fraction stereotactic body radiotherapy for locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72(3), 678-686.

Increased rate of hair regrowth in mice with constitutive overexpression of Del 1
Hsu, G. P., Mathy, J. A., Wang, Z., Xia, W., Sakamoto, G., & Yang, G. P. (2008). Increased rate of hair regrowth in mice with constitutive overexpression of Del 1. JOURNAL OF SURGICAL RESEARCH, 146(1), 73-80.

Current progress in keloid research and treatment
Butler, P. D., Longaker, M. T., & Yang, G. P. (2008). Current progress in keloid research and treatment. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 206(4), 731-741.

Use of organotypic coculture to study keloid biology
Butler, P. D., Ly, D. P., Longaker, M. T., & Yang, G. P. (2008). Use of organotypic coculture to study keloid biology. AMERICAN JOURNAL OF SURGERY, 195(2), 144-148.

Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites
Xia, W., Kong, W., Wang, Z., Phan, T.-T., Lim, I. J., & Yang, G. P. (2007). Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites. ANNALS OF SURGERY, 246(5), 886-895.

Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model
Yang, G. P., & Soetikno, R. M. (2007). Treatment of oesophageal ulcerations using endoscopic transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in a canine model. GUT, 56(3), 313-314.

Stereotactic body radiotherapy for unresectable pancreatic cancer
Chang, S. T., Goodman, K. A., Yang, G. R., & Koong, A. C. (2007). Stereotactic body radiotherapy for unresectable pancreatic cancer. IMRT, IGRT, SBRT: ADVANCES IN THE TREATMENT PLANNING AND DELIVERY OF RADIOTHERAPY, 40, 386-394.

Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation
Xia, W., Phan, T.-T., Lim, I. J., Longaker, M. T., & Yang, G. P. (2006). Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation. JOURNAL OF SURGICAL RESEARCH, 135(1), 156-163.

Functions of vitamin D, retinoic acid, and dexamethasone in mouse adipose-derived mesenchymal cells
Malladi, P., Xu, Y., Yang, G. P., & Longaker, M. T. (2006). Functions of vitamin D, retinoic acid, and dexamethasone in mouse adipose-derived mesenchymal cells. TISSUE ENGINEERING, 12(7), 2031-2040.

Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis
Dornhoefer, N., Spong, S., Bennewith, K., Salim, A., Klaus, S., & Giaccia, A. (2006). Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. CANCER RESEARCH, 66(11), 5816-5827.

Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
Chi, J. T., Wang, Z., Nuyten, D. Sa., Rodriguez, E. H., Schaner, M. E., & Brown, P. O. (2006). Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers. PLOS MEDICINE, 3(3), 395-409.

P38 MAP kinase mediates transforming growth factor-beta 2 transcription in human keloid fibroblasts
Xia, W., Longaker, M. T., & Yang, G. P. (2006). P38 MAP kinase mediates transforming growth factor-beta 2 transcription in human keloid fibroblasts. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 290(3), R501-R508.

Increased transcriptional response to mechanical strain in keloid fibroblasts due to increased focal adhesion complex formation
Wang, Z., Fong, K. D., Phan, T. T., Lim, I. J., Longaker, M. T., & Yang, G. P. (2006). Increased transcriptional response to mechanical strain in keloid fibroblasts due to increased focal adhesion complex formation. JOURNAL OF CELLULAR PHYSIOLOGY, 206(2), 510-517.

Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
Koong, A. C., Christofferson, E., Le, Q. T., Goodman, K. A., Ho, A., & Yang, G. P. (2005). Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(2), 320-323.

Complex epithelial-mesenchymal interactions modulate transforming growth factor-beta expression in keloid-derived cells
Xia, W., Phan, T. T., Lim, I. J., Longaker, M. T., & Yang, G. P. (2004). Complex epithelial-mesenchymal interactions modulate transforming growth factor-beta expression in keloid-derived cells. WOUND REPAIR AND REGENERATION, 12(5), 546-556.

Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer
Koong, A. C., Le, Q. T., Ho, A., Fong, B., Fisher, G., & Bastidas, J. A. (2004). Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 58(4), 1017-1021.

From scarless fetal wounds to keloids: Molecular studies in wound healing
Yang, G. P., Lim, I. J., Phan, T. T., Lorenz, H. P., & Longaker, M. T. (2003). From scarless fetal wounds to keloids: Molecular studies in wound healing. WOUND REPAIR AND REGENERATION, 11(6), 411-418.

Tissue engineering and regenerative medicine
Jenkins, D. D., Yang, G. P., Lorenz, H. P., Longaker, M. T., & Sylvester, K. G. (2003). Tissue engineering and regenerative medicine. CLINICS IN PLASTIC SURGERY, 30(4), 581-?.

FGF-2 stimulation affects calvarial osteoblast biology: Quantitative analysis of nine genes important for cranial suture biology by real-time reverse transcription polymerase chain reaction
Mathy, J. A., Lenton, K., Nacamuli, R. P., Fong, K. D., Song, H. M., & Longaker, M. T. (2003). FGF-2 stimulation affects calvarial osteoblast biology: Quantitative analysis of nine genes important for cranial suture biology by real-time reverse transcription polymerase chain reaction. PLASTIC AND RECONSTRUCTIVE SURGERY, 112(2), 528-539.

A spike in parathyroid hormone during neck exploration may cause a false-negative intraoperative assay result
Yang, G. P., LEVINE, S., & Weigel, R. J. (2001). A spike in parathyroid hormone during neck exploration may cause a false-negative intraoperative assay result. ARCHIVES OF SURGERY, 136(8), 945-949.

Genomic structure of the promoters of the human estrogen receptor-alpha gene demonstrate changes in chromatin structure induced by AP2 gamma
Schuur, E. R., McPherson, L. A., Yang, G. P., & Weigel, R. J. (2001). Genomic structure of the promoters of the human estrogen receptor-alpha gene demonstrate changes in chromatin structure induced by AP2 gamma. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(18), 15519-15526.

Distal emboli as an unusual late complication of a thrombosed arteriovenous hemodialysis graft
Yang, G. P., Lee, W. A., & Olcott, C. (2000). Distal emboli as an unusual late complication of a thrombosed arteriovenous hemodialysis graft. JOURNAL OF VASCULAR SURGERY, 32(6), 1229-1231.

Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes
Yang, G. P., Ross, D. T., Kuang, W. W., Brown, P. O., & Weigel, R. J. (1999). Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes. NUCLEIC ACIDS RESEARCH, 27(6), 1517-1523.