CyberKnife Stereotactic Radiosurgery Program

The Stanford CyberKnife Stereotactic Radiosurgery Program offers patients short wait times and the latest radiosurgery techniques. Patients also have access to specialized support groups for acoustic neuroma, brain tumors, meningioma, neurofibromatosis and trigeminal neuralgia.

Our Doctors

Care and Treatment

Features and Advantages of CyberKnife Technology

  • Frameless system

    Does not require a head frame screwed into the skull for immobilization, avoiding the pain, headache, nausea and risk of infection seen at times with stereotactic frames. Instead, a non-invasive thermoplastic head mask and image guidance allows stereotactic immobilization.

  • Flexible, frameless system, allowing single session or multi-session treatments

    Frameless design provides the flexibility to perform radiosurgery in either a single day or over multiple days which allows your treating physicians to decide the safest and most effective course of CyberKnife treatment [link to treatments/cyberknife.html].

    When constrained by frame-based systems requiring treatment in one day, some tumors are untreatable, or would require under-dosing of the tumor (risking tumor recurrence) or over-dosing of critical structures (risking injury to the brain).

  • Proven accuracy in both the brain and in extra-cranial sites

    Accuracy (<1mm ) is equivalent to rigid, frame-based systems. Recent total clinical accuracy for spine 0.61mm.*

  • Able to treat both intra-cranial and extra-cranial sites with stereotactic accuracy

    Your physicians have the ability to treat brain tumors, as well as tumors of the lung, spine, pancreas, liver, prostate, and other sites.

  • Multi-modality image fusion

    Your physicians have the option to use the best imaging study for your tumor, including CT, 4-dimensional CT, MRI and PET scans.

  • Image guidance, tracking tumors that move with respiration

    Movement of tumors during breathing, such as in the lung, pancreas, and liver, is automatically tracked and compensated, allowing minimization of treatment of normal structures and decreased toxicity of therapy.

  • Safely treat tumors that were previously untreatable

    Even in the setting of prior radiotherapy, your physicians may be able to re-treat tumors near the spine and spinal cord.

  • Linear accelerator-based treatment

    Megavoltage x-rays are used to treat the target, over 4 times more powerful than the energy from natural sources such as Cobalt. No need to dispose of radioactivity.

*  Ho et al A Study of the Accuracy of Cyberknife Spinal Radiosurgery using Skeletal Structure Tracking, Neurosurgery 60[ONS Suppl 1]:ONS-147-ONS-156, 2007

Additional features of the CyberKnife

-Iris™ Variable Aperture Collimator – Rapidly manipulates beam geometry to deliver up to 12 beam sizes from each linac position with characteristics virtually identical to that of fixed circular collimators.



- Xsight® Spine Tracking System – Eliminates the need for surgical implantation of fiducials by using the bony anatomy of the spine to automatically locate and track tumors, making radiosurgery more precise and less invasive.


- Synchrony® Respiratory Tracking System – Continuously synchronizes beam delivery to the motion of the tumor, allowing clinicians to significantly reduce margins while eliminating the need for gating or breath-holding techniques.


- Xsight® Lung Tracking System – Directly tracks the movement of lung tumors without fiducials while maintaining precision, reliability and self-adjusting repeatability.



- Monte Carlo Dose Calculation – Often considered the gold standard when treating lung tumors, the CyberKnife System’s Monte Carlo Dose Calculation produces results in minutes compared to what commonly requires hours or days with other systems.


For Patients

Stanford Hospital & Clinics is known worldwide for the advanced patient care provided by its doctors and staff.  We also provide a wide range of guest services and amenities to our patients and visitors. Learn more about preparing for a hospital stay, billing and financial services, and our other support programs in Patients & Visitors.  

International Patients

Phone: +1-650-723-8561

For Health Care Professionals


Phone: 1-866-742-4811 
Fax: 650-320-9443
Monday – Friday,  8:30 a.m. – 5 p.m.


Phone: 1-800-800-1551,  24 hours - 7 days a week

Stanford Hospital & Clinics provides comprehensive services to refer and track patients, as well as provides the latest information and news for physicians and office staff. For help with all referral needs and questions visit Referring Physicians.


Fax a referral form with supporting documentation to 650-320-9443.

Track your patients' progress and communicate with Stanford providers securely online.

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