Treating Kleine-Levin Syndrome

There is no specific, definitive treatment to cure or control KLS. Some aspects of the disease can be managed with medication, such as stimulants to combat the EDS, but this is most effective only once the episodes have already decreased in severity. In some cases, doctors have used lithium and carbamazepine, normally used to treat bipolar disorder, to prevent or shorten episodes. Beyond that, there really isn't much to do to control KLS, other than being as aware as possible of the effects of KLS, how to recognize episodes and to have sufficient support from family and friends.

Clinical Trials

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

Our Clinic


See a Stanford specialist to learn about your treatment options. Visit our clinic to make an appointment.

Call 650-723-6601 to make an appointment