Intrauterine Insemination (IUI) is an office procedure in which the sperm is carefully placed in the woman’s uterus, bypassing the cervix and allowing more sperm to reach the egg. For a woman, having an IUI is something similar to undergoing a PAP smear. The process involves the use of a very thin flexible catheter that facilitates passage of sperm. The procedure takes just a few minutes, and patients are able to return to regular activities immediately after the procedure. IUI may be recommended to increase the probability of pregnancy if a patient has unexplained infertility, male factor infertility (low sperm), problems with cervical mucous, or difficulty with intercourse.