Comparison of Transdermal and Oral Estrogens in Adolescent Girls With Ovarian Failure
Trial ID or NCT#
Status
Purpose
To directly compare the safety (by laboratory evaluation) and efficacy (feminization and growth) of three commonly used estrogen preparations in adolescent patients with ovarian failure, either due to congenital causes (Turner syndrome) or medical therapies. We hypothesize that transdermal estrogen will have equivalent efficacy and a more favorable safety profile in comparison with conventional oral estrogen replacement.
Official Title
Comparison of Transdermal and Oral Estrogens in Adolescents With Ovarian Failure
Eligibility Criteria
- in whom initiation of estrogen therapy has been recommended due to ovarian failure - Outpatients - age >=12 years to 17.99 years old
- - spontaneous menses - significant concurrent medical problem including: - Liver function tests (LFTs) 3 times normal - clotting disorder - ongoing cancer treatment
Investigator(s)
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Contact
Sejal Shah
6507235791
View on ClinicalTrials.gov