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Biography
Dr. Helen Bronte-Stewart is the John E Cahill Family Professor in the department of Neurology and Neurological Sciences. She is a neurologist, neurophysiologist and movement disorders specialist, who has used her training in mathematics and physics, bioengineering, neurology, movement disorders, and single unit electrophysiology in primates to develop a rigorous translational program in motor control research in human subjects with movement disorders. Dr. Bronte-Stewart is the Director of the Human Motor Control and Neuromodulation Laboratory, where she has developed computerized, quantitative measurements of motor behavior, which are being implemented in a wide range of Movement Disorders. She is also the Co-Director of the Stanford Balance Center, Her research investigates the brain’s contribution to abnormal movement in human subjects, using synchronous brain recordings and quantitative kinematics, and how these are modulated with different frequencies and patterns of neurostimulation. Dr. Bronte-Stewart’s team was the first in the United States to implant a sensing neurostimulator, from which they can record brain signals directly, and use the patient’s own neural activity to drive the first closed loop neurostimulation studies in Parkinson’s disease. This work has led to her team receiving a BRAIN Initiative grant to perform the first closed loop deep brain stimulation studies for gait impairment and freezing of gait in Parkinson’s disease. She is the Global Lead Investigator for the first pivotal international multicenter trial of adaptive DBS in Parkinson’s disease – the ADAPT-PD trial.
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Professional Summary
Education & Certifications
- Fellowship: UCSF Medical Center (1992) CA
- Medical Education: Perelman School of Medicine University of Pennsylvania (1984) PA
- Residency: Hospital of the University of Pennsylvania (1988) PA
- Internship: Hospital of the University of Pennsylvania (1985) PA
- Board Certification: American Board of Psychiatry and Neurology, Neurology (1991)
- BA, University of York, England, Mathematics and physics
- MSE, University of Pennsylvania, Bioengineering
- MD, University of Pennsylvania, Medicine
Administrative Appointments
- Co-director, Stanford Balance Center (2010 - Present)
- Director, Stanford Movement Disorders Center (1999 - Present)
- Division Chief, Movement Disorders division, Department of Neurology and Neurological Sciences (1999 - Present)
Publications
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Quantitative digitography (QDG): A sensitive measure of digital motor control in idiopathic Parkinson's disease
Bronte-Stewart, H. M., Ding, L., Alexander, C., Zhou, Y., & Moore, G. P. (2000). Quantitative digitography (QDG): A sensitive measure of digital motor control in idiopathic Parkinson's disease. MOVEMENT DISORDERS, 15(1), 36–47. -
Concurrent Parkinson tremors
Moore, G. P., Ding, L., & Bronte-Stewart, H. M. (2000). Concurrent Parkinson tremors. JOURNAL OF PHYSIOLOGY-LONDON, 529(1), 273–81. -
The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type
Silverberg, G. D., Heit, G., Huhn, S., Jaffe, R. A., Chang, S. D., Bronte-Stewart, H., … Saul, T. A. (2001). The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type. NEUROLOGY, 57(10), 1763–66. -
Postural instability in idiopathic Parkinson's disease: the role of medication and unilateral pallidotomy
Bronte-Stewart, H. M., Minn, A. Y., Rodrigues, K., Buckley, E. L., & Nashner, L. M. (2002). Postural instability in idiopathic Parkinson's disease: the role of medication and unilateral pallidotomy. Presented at the 52nd Annual Meeting of the American-Academy-of-Neurology, SAN DIEGO,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA: OXFORD UNIV PRESS. -
Parkinson's Disease: Surgical Options.
Bronte-Stewart, H. (2003). Parkinson's Disease: Surgical Options. Current Treatment Options in Neurology, 5(2), 131–47. -
Surgical therapy for dystonia.
Bronte-Stewart, H. (2003). Surgical therapy for dystonia. Current Neurology and Neuroscience Reports, 3(4), 296–305. -
Possible necessity for deep brain stimulation of both the ventralis intermedius and subthalamic nuclei to resolve Holmes tremor - Case report
Romanelli, P., Bronte-Stewart, H., COURTNEY, T., & Heit, G. (2003). Possible necessity for deep brain stimulation of both the ventralis intermedius and subthalamic nuclei to resolve Holmes tremor - Case report. JOURNAL OF NEUROSURGERY, 99(3), 566–71. -
Microelectrode recording revealing a somatotopic body map in the subthalamic nucleus in humans with Parkinson disease
Romanelli, P., Heit, G., Hill, B. C., Kraus, A., Hastie, T., & Bronte-Stewart, H. M. (2004). Microelectrode recording revealing a somatotopic body map in the subthalamic nucleus in humans with Parkinson disease. JOURNAL OF NEUROSURGERY, 100(4), 611–18. -
The functional organization of the sensorimotor region of the subthalamic nucleus
Romanelli, P., Bronte-Stewart, H., Heit, G., Schaal, D. W., & Esposito, V. (2004). The functional organization of the sensorimotor region of the subthalamic nucleus. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 82(5-6), 222–29. -
Quantitative measurements of alternating finger tapping in Parkinson's disease correlate with UPDRS motor disability and reveal the improvement in fine motor control from medication and deep brain stimulation.
Taylor Tavares, A. L., Jefferis, G. S. X. E., Koop, M., Hill, B. C., Hastie, T., Heit, G., & Bronte-Stewart, H. M. (2005). Quantitative measurements of alternating finger tapping in Parkinson's disease correlate with UPDRS motor disability and reveal the improvement in fine motor control from medication and deep brain stimulation. Movement Disorders , 20(10), 1286–98. -
The North American survey of placement and adjustment strategies for deep brain stimulation
Ondo, W. G., & Bronte-Stewart, H. (2005). The North American survey of placement and adjustment strategies for deep brain stimulation. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 83(4), 142–147. -
Intra-operative STN DBS attenuates the prominent beta rhythm in the STN in Parkinson's disease
Wingeier, B., Tcheng, T., Koop, M. M., Hill, B. C., Heit, G., & Bronte-Stewart, H. M. (2006). Intra-operative STN DBS attenuates the prominent beta rhythm in the STN in Parkinson's disease. EXPERIMENTAL NEUROLOGY, 197(1), 244–251. -
EXPRESSION OF MOTOR LEARNING IN THE RESPONSE OF THE PRIMATE VESTIBULOOCULAR REFLEX PATHWAY TO ELECTRICAL-STIMULATION
Broussard, D. M., BRONTESTEWART, H. M., & Lisberger, S. G. (1992). EXPRESSION OF MOTOR LEARNING IN THE RESPONSE OF THE PRIMATE VESTIBULOOCULAR REFLEX PATHWAY TO ELECTRICAL-STIMULATION. JOURNAL OF NEUROPHYSIOLOGY, 67(6), 1493–1508. -
Improvement in a quantitative measure of bradykinesia after microelectrode recording in patients with Parkinson's disease during deep brain stimulation surgery
Koop, M. M., Andrzejewski, A., Hill, B. C., Heit, G., & Bronte-Stewart, H. M. (2006). Improvement in a quantitative measure of bradykinesia after microelectrode recording in patients with Parkinson's disease during deep brain stimulation surgery. MOVEMENT DISORDERS, 21(5), 673–78. -
Practice parameter: Treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology
Pahwa, R., Factor, S. A., Lyons, K. E., Ondo, W. G., Gronseth, G., Bronte-Stewart, H., … Weiner, W. J. (2006). Practice parameter: Treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review) Report of the Quality Standards Subcommittee of the American Academy of Neurology. NEUROLOGY, 66(7), 983–995. -
Bilateral subthalamic nucleus deep brain stimulation improves certain aspects of postural control in Parkinson's disease, whereas medication does not
Shivitz, N., Miller Koop, M., Fahimi, J., Heit, G., & Bronte-Stewart, H. M. (2006). Bilateral subthalamic nucleus deep brain stimulation improves certain aspects of postural control in Parkinson's disease, whereas medication does not. MOVEMENT DISORDERS, 21(8), 1088–97. -
Quantitative measures of fine motor, limb, and postural bradykinesia in very early stage, untreated Parkinson's disease
Koop, M. M., Shivitz, N., & Bronte-Stewart, H. (2008). Quantitative measures of fine motor, limb, and postural bradykinesia in very early stage, untreated Parkinson's disease. MOVEMENT DISORDERS, 23(9), 1262–68. -
The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation
Bronte-Stewart, H., Barberini, C., Koop, M. M., Hill, B. C., Henderson, J. M., & Wingeier, B. (2009). The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation. EXPERIMENTAL NEUROLOGY, 215(1), 20–28. -
Excessive Postural Sway and the Risk of Falls at Different Stages of Parkinson's Disease
Frenklach, A., Louie, S., Koop, M. M., & Bronte-Stewart, H. (2009). Excessive Postural Sway and the Risk of Falls at Different Stages of Parkinson's Disease. MOVEMENT DISORDERS, 24(3), 377–85. -
Testing Objective Measures of Motor Impairment in Early Parkinson's Disease: Feasibility Study of an At-Home Testing Device
Goetz, C. G., Stebbins, G. T., Wolff, D., DeLeeuw, W., Bronte-Stewart, H., Elble, R., … Taylor, C. B. (2009). Testing Objective Measures of Motor Impairment in Early Parkinson's Disease: Feasibility Study of an At-Home Testing Device. MOVEMENT DISORDERS, 24(4), 551–556. -
Quantitative Lateralized Measures of Bradykinesia at Different Stages of Parkinson's Disease: The Role of the Less Affected Side
Louie, S., Koop, M. M., Frenklach, A., & Bronte-Stewart, H. (2009). Quantitative Lateralized Measures of Bradykinesia at Different Stages of Parkinson's Disease: The Role of the Less Affected Side. MOVEMENT DISORDERS, 24(13), 1991–97. -
Hybrid Cars May Interfere with Implanted Deep Brain Stimulators
Chen, C., Cole, W., & Bronte-Stewart, H. M. (2009). Hybrid Cars May Interfere with Implanted Deep Brain Stimulators. MOVEMENT DISORDERS, 24(15), 2290–91. -
Bilateral symmetry and coherence of subthalamic nuclei beta band activity in Parkinson's disease
de Solages, C., Hill, B. C., Koop, M. M., Henderson, J. M., & Bronte-Stewart, H. (2010). Bilateral symmetry and coherence of subthalamic nuclei beta band activity in Parkinson's disease. EXPERIMENTAL NEUROLOGY, 221(1), 260–66. -
Clinical Motor Outcome of Bilateral Subthalamic Nucleus Deep-Brain Stimulation for Parkinson's Disease Using Image-Guided Frameless Stereotaxy
Bronte-Stewart, H., Louie, S., Batya, S., & Henderson, J. M. (2010). Clinical Motor Outcome of Bilateral Subthalamic Nucleus Deep-Brain Stimulation for Parkinson's Disease Using Image-Guided Frameless Stereotaxy. NEUROSURGERY, 67(4), 1088–93. -
Maximal subthalamic beta hypersynchrony of the local field potential in Parkinson's disease is located in the central region of the nucleus
de Solages, C., Hill, B. C., Yu, H., Henderson, J. M., & Bronte-Stewart, H. (2011). Maximal subthalamic beta hypersynchrony of the local field potential in Parkinson's disease is located in the central region of the nucleus. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 82(12), 1387–89. -
Deep Brain Stimulation in "On"-State Parkinson Hyperpyrexia
Klepitskaya, O., Cole, W., Henderson, J., & Bronte-Stewart, H. (2011). Deep Brain Stimulation in "On"-State Parkinson Hyperpyrexia. NEUROLOGY, 76(7), S69–S71. -
PROPERTIES OF PATHWAYS THAT MEDIATE MOTOR LEARNING IN THE VESTIBULOOCULAR REFLEX OF MONKEYS
Lisberger, S. G., Broussard, D. M., & BRONTESTEWART, H. M. (1990). PROPERTIES OF PATHWAYS THAT MEDIATE MOTOR LEARNING IN THE VESTIBULOOCULAR REFLEX OF MONKEYS. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 55, 813–822. -
Inclusion and Exclusion Criteria for DBS in Dystonia
Bronte-Stewart, H., Taira, T., Valldeoriola, F., Merello, M., Marks, W. J., Albanese, A., … Moro, E. (2011). Inclusion and Exclusion Criteria for DBS in Dystonia. MOVEMENT DISORDERS, 26, S5–S16. -
Human Subthalamic Neuron Spiking Exhibits Subtle Responses to Sedatives
MacIver, M. B., Bronte-Stewart, H. M., Henderson, J. M., Jaffe, R. A., & Brock-Utne, J. G. (2011). Human Subthalamic Neuron Spiking Exhibits Subtle Responses to Sedatives. ANESTHESIOLOGY, 115(2), 254–64. -
Repetitive stepping in place identifies and measures freezing episodes in subjects with Parkinson's disease
Nantel, J., de Solages, C., & Bronte-Stewart, H. (2011). Repetitive stepping in place identifies and measures freezing episodes in subjects with Parkinson's disease. GAIT & POSTURE, 34(3), 329–33. -
Socioeconomic Trends in Deep Brain Stimulation (DBS) Surgery
Lad, S. P., Kalanithi, P. S., Patil, C. G., Itthimathin, P., Batya, S., Bronte-Stewart, H., … Henderson, J. M. (2010). Socioeconomic Trends in Deep Brain Stimulation (DBS) Surgery. NEUROMODULATION, 13(3), 182–86. -
Effect of medication and STN-DBS on postural control in subjects with Parkinson's disease
Nantel, J., McDonald, J. C., & Bronte-Stewart, H. (2012). Effect of medication and STN-DBS on postural control in subjects with Parkinson's disease. PARKINSONISM & RELATED DISORDERS, 18(3), 285–89. -
High frequency deep brain stimulation attenuates subthalamic and cortical rhythms in Parkinson's disease
Whitmer, D., de Solages, C., Hill, B., Yu, H., Henderson, J. M., & Bronte-Stewart, H. (2012). High frequency deep brain stimulation attenuates subthalamic and cortical rhythms in Parkinson's disease. FRONTIERS IN HUMAN NEUROSCIENCE, 6. -
DEFICITS IN VISUOSPATIAL PROCESSING CONTRIBUTE TO QUANTITATIVE MEASURES OF FREEZING OF GAIT IN PARKINSON'S DISEASE
Nantel, J., McDonald, J. C., Tan, S., & Bronte-Stewart, H. (2012). DEFICITS IN VISUOSPATIAL PROCESSING CONTRIBUTE TO QUANTITATIVE MEASURES OF FREEZING OF GAIT IN PARKINSON'S DISEASE. NEUROSCIENCE, 221, 151–156. -
Resting Beta Hypersynchrony in Secondary Dystonia and Its Suppression During Pallidal Deep Brain Stimulation in DYT3+ Lubag Dystonia.
Whitmer, D., de Solages, C., Hill, B. C., Yu, H., & Bronte-Stewart, H. (2013). Resting Beta Hypersynchrony in Secondary Dystonia and Its Suppression During Pallidal Deep Brain Stimulation in DYT3+ Lubag Dystonia. Neuromodulation , 16(3), 200–205. -
Perceptual errors increase with movement duration and may contribute to hypokinesia in Parkinson's disease.
Koop, M. M., Hill, B. C., & Bronte-Stewart, H. M. (2013). Perceptual errors increase with movement duration and may contribute to hypokinesia in Parkinson's disease. Neuroscience, 243, 1–13. -
LACUNAR INFARCTION OF THE BASAL GANGLIA AS A COMPLICATION OF HEMOLYTIC-UREMIC SYNDROME - MRI AND CLINICAL CORRELATIONS
DiMario, F. J., BRONTESTEWART, H., Sherbotie, J., & Turner, M. E. (1987). LACUNAR INFARCTION OF THE BASAL GANGLIA AS A COMPLICATION OF HEMOLYTIC-UREMIC SYNDROME - MRI AND CLINICAL CORRELATIONS. CLINICAL PEDIATRICS, 26(11), 586–590. -
NEURAL BASIS FOR MOTOR LEARNING IN THE VESTIBULOOCULAR REFLEX OF PRIMATES .2. CHANGES IN THE RESPONSES OF HORIZONTAL GAZE VELOCITY PURKINJE-CELLS IN THE CEREBELLAR FLOCCULUS AND VENTRAL PARAFLOCCULUS
Lisberger, S. G., PAVELKO, T. A., BRONTESTEWART, H. M., & Stone, L. S. (1994). NEURAL BASIS FOR MOTOR LEARNING IN THE VESTIBULOOCULAR REFLEX OF PRIMATES .2. CHANGES IN THE RESPONSES OF HORIZONTAL GAZE VELOCITY PURKINJE-CELLS IN THE CEREBELLAR FLOCCULUS AND VENTRAL PARAFLOCCULUS. JOURNAL OF NEUROPHYSIOLOGY, 72(2), 954–973. -
PHYSIOLOGICAL-PROPERTIES OF VESTIBULAR PRIMARY AFFERENTS THAT MEDIATE MOTOR LEARNING AND NORMAL PERFORMANCE OF THE VESTIBULOOCULAR REFLEX IN MONKEYS
BRONTESTEWART, H. M., & Lisberger, S. G. (1994). PHYSIOLOGICAL-PROPERTIES OF VESTIBULAR PRIMARY AFFERENTS THAT MEDIATE MOTOR LEARNING AND NORMAL PERFORMANCE OF THE VESTIBULOOCULAR REFLEX IN MONKEYS. JOURNAL OF NEUROSCIENCE, 14(3), 1290–1308. -
A physiological model of the effects of surgery on postural instability in Parkinson?s Disease and in Essential Tremor
A physiological model of the effects of surgery on postural instability in Parkinson?s Disease and in Essential Tremor. (2001). Control of Posture and Gait. -
A longitudinal program for biomarker development in Parkinson?s disease: a feasibility study
A longitudinal program for biomarker development in Parkinson?s disease: a feasibility study. (2009). Movement Disorders, 24(14). -
A comparison of treatment thresholds in two large Parkinson?s disease clinical trial cohorts
A comparison of treatment thresholds in two large Parkinson?s disease clinical trial cohorts. (2009). Movement Disorders, 24(16). -
Deep Brain Stimulation for Parkinson?s Disease. An expert consensus and review of key issues
Deep Brain Stimulation for Parkinson?s Disease. An expert consensus and review of key issues. (2011). Archives of Neurology, 68(2). -
Immediate versus delayed switch from levodopa/carbidopa to levodopa/carbidopa/entacapone: effects on motor function and quality of life in patients with Parkinson's disease with end-of-dose wearing off
Immediate versus delayed switch from levodopa/carbidopa to levodopa/carbidopa/entacapone: effects on motor function and quality of life in patients with Parkinson's disease with end-of-dose wearing off. (2011). Int J Neurosci, 121(11). -
New drugs/devices ? Deep brain stimulation (DBS)
New drugs/devices ? Deep brain stimulation (DBS). (2012). Neurology Clin Pract, 12(2). -
Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson?s disease
Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson?s disease. (2007). Neurology, 69. -
Postural instability in Parkinson?s Disease: Opposing effects of treatment on sensory and motor components
Postural instability in Parkinson?s Disease: Opposing effects of treatment on sensory and motor components. (2001). Control of Posture and Gait. -
Rhythmic coritcal activity and its relation to movement in normal subjects and patients with movement disorders
Rhythmic coritcal activity and its relation to movement in normal subjects and patients with movement disorders. (1999). Journal of Physiology, 518. -
Improved efficacy of temporally non-regular deep brain stimulation in Parkinson's disease
Brocker, D. T., Swan, B. D., Turner, D. A., Gross, R. E., Tatter, S. B., Koop, M. M., … Grill, W. M. (2013). Improved efficacy of temporally non-regular deep brain stimulation in Parkinson's disease. EXPERIMENTAL NEUROLOGY, 239, 60–67. -
The effect of medication and the role of postural instability in different components of freezing of gait (FOG).
Nantel, J., & Bronte-Stewart, H. (2014). The effect of medication and the role of postural instability in different components of freezing of gait (FOG). Parkinsonism & Related Disorders, 20(4), 447–51. -
Sixty Hertz Neurostimulation Amplifies Subthalamic Neural Synchrony in Parkinson's Disease
Blumenfeld, Z., Velisar, A., Koop, M. M., Hill, B. C., Shreve, L. A., Quinn, E. J., … Bronte-Stewart, H. (2015). Sixty Hertz Neurostimulation Amplifies Subthalamic Neural Synchrony in Parkinson's Disease. PLOS ONE, 10(3). -
Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease.
Müller-Oehring, E. M., Sullivan, E. V., Pfefferbaum, A., Huang, N. C., Poston, K. L., Bronte-Stewart, H. M., & Schulte, T. (2015). Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease. Brain Imaging and Behavior, 9(3), 619–38. -
Proceedings of the Second Annual Deep Brain Stimulation Think Tank: What's in the Pipeline
Gunduz, A., Morita, H., Rossi, P. J., Allen, W. L., Alterman, R. L., Bronte-Stewart, H., … Okun, M. S. (2015). Proceedings of the Second Annual Deep Brain Stimulation Think Tank: What's in the Pipeline. INTERNATIONAL JOURNAL OF NEUROSCIENCE, 125(7), 475–85. -
Aging with HIV-1 Infection: Motor Functions, Cognition, and Attention - A Comparison with Parkinson's Disease
DeVaughn, S., Mueller-Oehring, E. M., Markey, B., Bronte-Stewart, H. M., & Schulte, T. (2015). Aging with HIV-1 Infection: Motor Functions, Cognition, and Attention - A Comparison with Parkinson's Disease. NEUROPSYCHOLOGY REVIEW, 25(4), 424–38. -
High Frequency Deep Brain Stimulation and Neural Rhythms in Parkinson's Disease
Blumenfeld, Z., & Bronte-Stewart, H. (2015). High Frequency Deep Brain Stimulation and Neural Rhythms in Parkinson's Disease. NEUROPSYCHOLOGY REVIEW, 25(4), 384–97. -
Beta Oscillations in Freely Moving Parkinson's Subjects Are Attenuated During Deep Brain Stimulation
Quinn, E. J., Blumenfeld, Z., Velisar, A., Koop, M. M., Shreve, L. A., Trager, M. H., … Bronte-Stewart, H. (2015). Beta Oscillations in Freely Moving Parkinson's Subjects Are Attenuated During Deep Brain Stimulation. MOVEMENT DISORDERS, 30(13), 1750–58. -
Kinematic Adaptive Deep Brain Stimulation for Resting Tremor in Parkinson's Disease.
Malekmohammadi, M., Herron, J., Velisar, A., Blumenfeld, Z., Trager, M. H., Chizeck, H. J., & Brontë-Stewart, H. (2016). Kinematic Adaptive Deep Brain Stimulation for Resting Tremor in Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. -
Arrhythmokinesis is evident during unimanual not bimanual finger tapping in Parkinson's disease.
Trager, M. H., Velisar, A., Koop, M. M., Shreve, L., Quinn, E., & Bronte-Stewart, H. (2015). Arrhythmokinesis is evident during unimanual not bimanual finger tapping in Parkinson's disease. Journal of Clinical Movement Disorders, 2, 8-? -
Long-term detection of Parkinsonian tremor activity from subthalamic nucleus local field potentials.
Houston, B., Blumenfeld, Z., Quinn, E., Bronte-Stewart, H., & Chizeck, H. (2015). Long-term detection of Parkinsonian tremor activity from subthalamic nucleus local field potentials. Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2015, 3427–3431. -
Auditory cueing in Parkinson's patients with freezing of gait. What matters most: Action-relevance or cue-continuity?
Young, W. R., Shreve, L., Quinn, E. J., Craig, C., & Bronte-Stewart, H. (2016). Auditory cueing in Parkinson's patients with freezing of gait. What matters most: Action-relevance or cue-continuity? NEUROPSYCHOLOGIA, 87, 54–62. -
Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease
Mueller-Oehring, E. M., Sullivan, E. V., Pfefferbaum, A., Huang, N. C., Poston, K. L., Bronte-Stewart, H. M., & Schulte, T. (2015). Task-rest modulation of basal ganglia connectivity in mild to moderate Parkinson's disease. BRAIN IMAGING AND BEHAVIOR, 9(3), 619–38. -
Quantitative measurements of Parkinson's disease correlate alternating finger tapping in with UPDRS motor disability and reveal the improvement in fine motor control from medication and deep brain stimulation
Tavares, A. L. T., Jefferis, G. S. X. E., Koop, M., Hill, B. C., Hastie, T., Heit, G., & Bronte-Stewart, H. M. (2005). Quantitative measurements of Parkinson's disease correlate alternating finger tapping in with UPDRS motor disability and reveal the improvement in fine motor control from medication and deep brain stimulation. MOVEMENT DISORDERS, 20(10), 1286–98. -
Subthalamic beta oscillations are attenuated after withdrawal of chronic high frequency neurostimulation in Parkinson's disease.
Trager, M. H., Koop, M. M., Velisar, A., Blumenfeld, Z., Nikolau, J. S., Quinn, E. J., … Bronte-Stewart, H. (2016). Subthalamic beta oscillations are attenuated after withdrawal of chronic high frequency neurostimulation in Parkinson's disease. Neurobiology of Disease, 96, 22–30. -
Aging with HIV-1 Infection: Motor Functions, Cognition, and Attention--A Comparison with Parkinson's Disease.
DeVaughn, S., Müller-Oehring, E. M., Markey, B., Brontë-Stewart, H. M., & Schulte, T. (2015). Aging with HIV-1 Infection: Motor Functions, Cognition, and Attention--A Comparison with Parkinson's Disease. Neuropsychology Review, 25(4), 424–438. -
PROPERTIES OF PATHWAYS THAT MEDIATE MOTOR LEARNING IN THE VESTIBULOOCULAR REFLEX OF MONKEYS
Lisberger, S. G., Broussard, D. M., & BRONTESTEWART, H. M. (1990). PROPERTIES OF PATHWAYS THAT MEDIATE MOTOR LEARNING IN THE VESTIBULOOCULAR REFLEX OF MONKEYS. Presented at the SYMP ON THE BRAIN, COLD SPRING HARBOR,NY: COLD SPRING HARBOR LABORATORY PRESS. -
Subthalamic oscillations and phase amplitude coupling are greater in the more affected hemisphere in Parkinson's disease.
Shreve, L. A., Velisar, A., Malekmohammadi, M., Koop, M. M., Trager, M., Quinn, E. J., … Brontë-Stewart, H. (2017). Subthalamic oscillations and phase amplitude coupling are greater in the more affected hemisphere in Parkinson's disease. Clinical Neurophysiology , 128(1), 128–37. -
Sixty-hertz stimulation improves bradykinesia and amplifies subthalamic low-frequency oscillations.
Blumenfeld, Z., Koop, M. M., Prieto, T. E., Shreve, L. A., Velisar, A., Quinn, E. J., … Brontë-Stewart, H. (2017). Sixty-hertz stimulation improves bradykinesia and amplifies subthalamic low-frequency oscillations. Movement Disorders , 32(1), 80–88. -
Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies.
Deeb, W., Giordano, J. J., Rossi, P. J., Mogilner, A. Y., Gunduz, A., Judy, J. W., … Okun, M. S. (2016). Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies. Frontiers in Integrative Neuroscience, 10, 38-? -
Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man.
Wu, H., Miller, K. J., Blumenfeld, Z., Williams, N. R., Ravikumar, V. K., Lee, K. E., … Halpern, C. H. (2018). Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man. Proceedings of the National Academy of Sciences of the United States of America, 115(1), 192–97. -
Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank
Ramirez-Zamora, A., Giordano, J. J., Gunduz, A., Brown, P., Sanchez, J. C., Foote, K. D., … Okun, M. S. (2018). Evolving Applications, Technological Challenges and Future Opportunities in Neuromodulation: Proceedings of the Fifth Annual Deep Brain Stimulation Think Tank. FRONTIERS IN NEUROSCIENCE, 11, 734. -
Coordinated Reset Vibrotactile Stimulation Shows Prolonged Improvement in Parkinson's Disease
Syrkin-Nikolau, J., Neuville, R., O'Day, J., Anidi, C., Koop, M. M., Martin, T., … Bronte-Stewart, H. (2018). Coordinated Reset Vibrotactile Stimulation Shows Prolonged Improvement in Parkinson's Disease. MOVEMENT DISORDERS, 33(1), 179–80. -
Subthalamic neural entropy is a feature of freezing of gait in freely moving people with Parkinson's disease
Syrkin-Nikolau, J., Koop, M. M., Prieto, T., Anidi, C., Afzal, M. F., Velisar, A., … Bronte-Stewart, H. (2017). Subthalamic neural entropy is a feature of freezing of gait in freely moving people with Parkinson's disease. NEUROBIOLOGY OF DISEASE, 108, 288–97. -
Model Predictive Control of Deep Brain Stimulation for Parkinsonian Tremor
Haddock, A., Velisar, A., Herron, J., Bronte-Stewart, H., & Chizeck, H. J. (2017). Model Predictive Control of Deep Brain Stimulation for Parkinsonian Tremor. 2017 8TH INTERNATIONAL IEEE/EMBS CONFERENCE ON NEURAL ENGINEERING (NER), 358–62. -
Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease.
Anidi, C. M., O'Day, J. J., Anderson, R. W., Afzal, M. F., Syrkin-Nikolau, J., Velisar, A., & Bronte-Stewart, H. M. (2018). Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease. Neurobiology of Disease. -
Information processing deficit in older adults with HIV infection: A comparison with Parkinson's disease.
Sundaram, S., Muller-Oehring, E. M., Fama, R., Bronte-Stewart, H. M., Poston, K. L., Goodcase, R., … Schulte, T. (2018). Information processing deficit in older adults with HIV infection: A comparison with Parkinson's disease. Neuropsychology. -
Biophysical basis of subthalamic local field potentials recorded from deep brain stimulation electrodes
Maling, N., Lempka, S. F., Blumenfeld, Z., Bronte-Stewart, H., & McIntyre, C. C. (2018). Biophysical basis of subthalamic local field potentials recorded from deep brain stimulation electrodes. JOURNAL OF NEUROPHYSIOLOGY, 120(4), 1932–44. -
Motor function impairment in chronic HIV is similar but less severe to that seen in Parkinson's disease
Bronte-Stewart, H., Prabhakar, V., Martin, T., Trager, M., Velisar, A., Koop, M. M., … Schulte, T. (2018). Motor function impairment in chronic HIV is similar but less severe to that seen in Parkinson's disease. NEUROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Efficacy of Subthalamic Neural Closed-loop Deep Brain Stimulation for Bradykinesia in Parkinson's Disease
Bronte-Stewart, H., Afzal, M. F., Velisar, A., & Anidi, C. (2018). Efficacy of Subthalamic Neural Closed-loop Deep Brain Stimulation for Bradykinesia in Parkinson's Disease. NEUROLOGY, 90. -
Sixty hertz subthalamic deep brain stimulation improves freezing of gait with less attenuation of beta band power than 140Hz stimulation
Anidi, C., O'Day, J., Afzal, M. F., Syrkin-Nikolau, J., Velisar, A., & Bronte-Stewart, H. (2018). Sixty hertz subthalamic deep brain stimulation improves freezing of gait with less attenuation of beta band power than 140Hz stimulation. NEUROLOGY, 90. -
Unilateral pallidotomy improves postural instability (PI) in patients with idiopathic Parkinson's disease (IPD) and improves the detrimental effect of medication on the vestibular control of posture
Bronte-Stewart, H., Rodrigues, K., & Nashner, L. (2000). Unilateral pallidotomy improves postural instability (PI) in patients with idiopathic Parkinson's disease (IPD) and improves the detrimental effect of medication on the vestibular control of posture. NEUROLOGY, 54(7), A457–A458. -
Central vestibular mechanisms of balance may be deficient in idiopathic parkinson's disease (IPD) and adversely affected by medication
Rodrigues, K., Nashner, L., & Bronte-Stewart, H. (2000). Central vestibular mechanisms of balance may be deficient in idiopathic parkinson's disease (IPD) and adversely affected by medication. NEUROLOGY, 54(7), A446. -
Deep brain stimulation.
Bronte-Stewart, H. (2012). Deep brain stimulation. Neurology. Clinical Practice, 2(1), 67–71. -
Editorial Comments to the Special Issue of Neuropsychology Review on the Basic Neuroscience and Neuropsychology of Selective Movement Disorders
Schulte, T., & Bronte-Stewart, H. (2015). Editorial Comments to the Special Issue of Neuropsychology Review on the Basic Neuroscience and Neuropsychology of Selective Movement Disorders. NEUROPSYCHOLOGY REVIEW, 25(4), 369–70. -
The Role of Deep Brain Stimulation (DBS) in the Treatment of Postural Instability and Gait Disorders of Parkinson's Disease
Bronte-Stewart, H. (2008). The Role of Deep Brain Stimulation (DBS) in the Treatment of Postural Instability and Gait Disorders of Parkinson's Disease. DEEP BRAIN STIMULATION IN NEUROLOGICAL AND PSYCHIATRIC DISORDERS, 333–58. -
Outcome of pallidal surgery in primary versus secondary dystonia
Kilgore, S. M., & Bronte-Stewart, H. (2002). Outcome of pallidal surgery in primary versus secondary dystonia. NEUROLOGY, 58(7), A395. -
Superior outcomes of bilateral STN DBS in IPD attributed to precise intraoperative localization techniques
Bronte-Stewart, H. M., Hill, B. C., McGuire, K., Minn, A. Y., Courtney, T. A., & Heit, G. (2001). Superior outcomes of bilateral STN DBS in IPD attributed to precise intraoperative localization techniques. NEUROLOGY, 56(8), A279. -
Postural instability is common in patients with essential tremor and is improved after thalamic deep brain stimulation
Minn, A. Y., & Bronte-Stewart, H. M. (2001). Postural instability is common in patients with essential tremor and is improved after thalamic deep brain stimulation. NEUROLOGY, 56(8), A24–A25. -
Dual threshold neural closed loop deep brain stimulation in Parkinson disease patients.
Velisar, A., Syrkin-Nikolau, J., Blumenfeld, Z., Trager, M. H., Afzal, M. F., Prabhakar, V., & Bronte-Stewart, H. (2019). Dual threshold neural closed loop deep brain stimulation in Parkinson disease patients. Brain Stimulation. -
Beta oscillations in freely moving Parkinson's subjects are attenuated during deep brain stimulation.
Quinn, E. J., Blumenfeld, Z., Velisar, A., Koop, M. M., Shreve, L. A., Trager, M. H., … Brontë-Stewart, H. (2015). Beta oscillations in freely moving Parkinson's subjects are attenuated during deep brain stimulation. Movement Disorders : Official Journal of the Movement Disorder Society, 30(13), 1750–8. -
Establishing a framework for neuropathological correlates and glymphatic system functioning in Parkinson's disease.
Sundaram, S., Hughes, R. L., Peterson, E., Muller-Oehring, E. M., Bronte-Stewart, H. M., Poston, K. L., … Schulte, T. (2019). Establishing a framework for neuropathological correlates and glymphatic system functioning in Parkinson's disease. Neuroscience and Biobehavioral Reviews. -
Reply to letter to the editor "Adaptive DBS in Parkinson's disease: Headlines, perspectives and challenges".
Velisar, A., & Bronte-Stewart, H. (2019). Reply to letter to the editor "Adaptive DBS in Parkinson's disease: Headlines, perspectives and challenges". Brain Stimulation. -
Information Processing Deficit in Older Adults With HIV Infection: A Comparison With Parkinson's Disease
Sundaram, S., Mueller-Oehring, E. M., Fama, R., Bronte-Stewart, H. M., Poston, K. L., Goodcase, R., … Schulte, T. (2019). Information Processing Deficit in Older Adults With HIV Infection: A Comparison With Parkinson's Disease. NEUROPSYCHOLOGY, 33(2), 157–68. -
Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease
Anidi, C., O'Day, J. J., Anderson, R. W., Afzal, M. F., Syrkin-Nikolau, J., Velisar, A., & Bronte-Stewart, H. M. (2018). Neuromodulation targets pathological not physiological beta bursts during gait in Parkinson's disease. NEUROBIOLOGY OF DISEASE, 120, 107–17. -
Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics
Ramirez-Zamora, A., Giordano, J., Boyden, E. S., Gradinaru, V., Gunduz, A., Starr, P. A., … Okun, M. S. (2019). Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. FRONTIERS IN NEUROSCIENCE, 13. -
Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics.
Ramirez-Zamora, A., Giordano, J., Boyden, E. S., Gradinaru, V., Gunduz, A., Starr, P. A., … Okun, M. S. (2019). Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. Frontiers in Neuroscience, 13, 936. -
Alterations of Brain Signal Oscillations in Older Individuals with HIV Infection and Parkinson's Disease.
Muller-Oehring, E. M., Hong, J.-Y., Hughes, R. L., Kwon, D., Bronte-Stewart, H. M., Poston, K. L., & Schulte, T. (2020). Alterations of Brain Signal Oscillations in Older Individuals with HIV Infection and Parkinson's Disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. -
The turning and barrier course reveals gait parameters for detecting freezing of gait and measuring the efficacy of deep brain stimulation.
O'Day, J., Syrkin-Nikolau, J., Anidi, C., Kidzinski, L., Delp, S., & Bronte-Stewart, H. (2020). The turning and barrier course reveals gait parameters for detecting freezing of gait and measuring the efficacy of deep brain stimulation. PloS One, 15(4), e0231984. -
Safety of Plasma Infusions in Parkinson's Disease.
Parker, J. E., Martinez, A., Deutsch, G. K., Prabhakar, V., Lising, M., Kapphahn, K. I., … Bronte-Stewart, H. M. (2020). Safety of Plasma Infusions in Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. -
Neural Closed loop deep brain stimulation for freezing of Gait.
Petrucci, M. N., Neuville, R. S., Afzal, M. F., Velisar, A., Anidi, C. M., Anderson, R. W., … Bronte-Stewart, H. M. (2020). Neural Closed loop deep brain stimulation for freezing of Gait. Brain Stimulation. -
Perspective: Evolution of Control Variables and Policies for Closed-Loop Deep Brain Stimulation for Parkinson's Disease Using Bidirectional Deep-Brain-Computer Interfaces
Bronte-Stewart, H. M., Petrucci, M. N., O'Day, J. J., Afzal, M. F., Parker, J. E., Kehnemouyi, Y. M., … Hoffman, S. L. (2020). Perspective: Evolution of Control Variables and Policies for Closed-Loop Deep Brain Stimulation for Parkinson's Disease Using Bidirectional Deep-Brain-Computer Interfaces. FRONTIERS IN HUMAN NEUROSCIENCE, 14. -
Cognitive and motor deficits in older adults with HIV infection: Comparison with normal ageing and Parkinson's disease.
Müller-Oehring, E. M., Fama, R., Levine, T. F., Hardcastle, C., Goodcase, R., Martin, T., … Schulte, T. (2020). Cognitive and motor deficits in older adults with HIV infection: Comparison with normal ageing and Parkinson's disease. Journal of Neuropsychology. -
Gait variability is linked to the atrophy of the Nucleus Basalis of Meynert and is resistant to STN DBS in Parkinson's disease.
Wilkins, K. B., Parker, J. E., & Bronte-Stewart, H. M. (2020). Gait variability is linked to the atrophy of the Nucleus Basalis of Meynert and is resistant to STN DBS in Parkinson's disease. Neurobiology of Disease, 105134. -
A Closed-loop Deep Brain Stimulation Approach for Mitigating Burst Durations in People with Parkinson's Disease.
Petrucci, M. N., Anderson, R. W., O'Day, J. J., Kehnemouyi, Y. M., Herron, J. A., & Bronte-Stewart, H. M. (2020). A Closed-loop Deep Brain Stimulation Approach for Mitigating Burst Durations in People with Parkinson's Disease. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2020, 3617–20. -
Demonstration of Kinematic-Based Closed-loop Deep Brain Stimulation for Mitigating Freezing of Gait in People with Parkinson's Disease.
O'Day, J. J., Kehnemouyi, Y. M., Petrucci, M. N., Anderson, R. W., Herron, J. A., & Bronte-Stewart, H. M. (2020). Demonstration of Kinematic-Based Closed-loop Deep Brain Stimulation for Mitigating Freezing of Gait in People with Parkinson's Disease. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2020, 3612–16. -
Perspective: Evolution of Control Variables and Policies for Closed-Loop Deep Brain Stimulation for Parkinson's Disease Using Bidirectional Deep-Brain-Computer Interfaces.
Bronte-Stewart, H. M., Petrucci, M. N., O'Day, J. J., Afzal, M. F., Parker, J. E., Kehnemouyi, Y. M., … Hoffman, S. L. (2020). Perspective: Evolution of Control Variables and Policies for Closed-Loop Deep Brain Stimulation for Parkinson's Disease Using Bidirectional Deep-Brain-Computer Interfaces. Frontiers in Human Neuroscience, 14, 353. -
Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson’s Disease
Prabhakar, V., Martin, T., Müller-Oehring, E. M., Goodcase, R., Schulte, T., Poston, K. L., & Brontë-Stewart, H. M. (2020). Quantitative Digitography Measures Fine Motor Disturbances in Chronically Treated HIV Similar to Parkinson’s Disease. Frontier in Aging Neuroscience, 539598. -
A validated measure of rigidity in Parkinson's disease using alternating finger tapping on an engineered keyboard.
Trager, M. H., Wilkins, K. B., Koop, M. M., & Bronte-Stewart, H. (2020). A validated measure of rigidity in Parkinson's disease using alternating finger tapping on an engineered keyboard. Parkinsonism & Related Disorders, 81, 161–64. -
Modulation of beta bursts in subthalamic sensorimotor circuits predicts improvement in bradykinesia.
Kehnemouyi, Y. M., Wilkins, K. B., Anidi, C. M., Anderson, R. W., Afzal, M. F., & Bronte-Stewart, H. M. (2020). Modulation of beta bursts in subthalamic sensorimotor circuits predicts improvement in bradykinesia. Brain : a Journal of Neurology. -
A Closed-loop Deep Brain Stimulation Approach for Mitigating Burst Durations in People with Parkinson's Disease
Petrucci, M. N., Anderson, R. W., O'Day, J. J., Kehnemouyi, Y. M., Herron, J. A., & Bronte-Stewart, H. M. (2020). A Closed-loop Deep Brain Stimulation Approach for Mitigating Burst Durations in People with Parkinson's Disease. 42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20. IEEE. -
Demonstration of Kinematic-Based Closed-loop Deep Brain Stimulation for Mitigating Freezing of Gait in People with Parkinson's Disease
O'Day, J. J., Kehnemouyi, Y. M., Petrucci, M. N., Anderson, R. W., Herron, J. A., & Bronte-Stewart, H. M. (2020). Demonstration of Kinematic-Based Closed-loop Deep Brain Stimulation for Mitigating Freezing of Gait in People with Parkinson's Disease. 42ND ANNUAL INTERNATIONAL CONFERENCES OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY: ENABLING INNOVATIVE TECHNOLOGIES FOR GLOBAL HEALTHCARE EMBC'20. IEEE. -
Gait Parameters Measured from Wearable Sensors Reliably Detect Freezing of Gait in a Stepping in Place Task.
Diep, C., O'Day, J., Kehnemouyi, Y., Burnett, G., & Bronte-Stewart, H. (2021). Gait Parameters Measured from Wearable Sensors Reliably Detect Freezing of Gait in a Stepping in Place Task. Sensors (Basel, Switzerland), 21(8). -
The effects of mood and cognition on daily functioning and quality of life in older people living with HIV and people with Parkinson's disease.
Patel, S. S., Muller-Oehring, E. M., DeVaughn, S., Fama, R., Bronte-Stewart, H. M., Poston, K. L., & Schulte, T. (2021). The effects of mood and cognition on daily functioning and quality of life in older people living with HIV and people with Parkinson's disease. Neuropsychology. -
Ramp Rate Evaluation and Configuration for Safe and Tolerable Closed-Loop Deep Brain Stimulation
Petrucci, M. N., Wilkins, K. B., Orthlieb, G. C., Kehnemouyi, Y. M., O'Day, J. J., Herron, J. A., & Bronte-Stewart, H. M. (2021). Ramp Rate Evaluation and Configuration for Safe and Tolerable Closed-Loop Deep Brain Stimulation. 2021 10TH INTERNATIONAL IEEE/EMBS CONFERENCE ON NEURAL ENGINEERING (NER). IEEE. -
Lack of progression of beta dynamics after long-term subthalamic neurostimulation.
Anderson, R. W., Wilkins, K. B., Parker, J. E., Petrucci, M. N., Kehnemouyi, Y., Neuville, R. S., … Bronte-Stewart, H. M. (2021). Lack of progression of beta dynamics after long-term subthalamic neurostimulation. Annals of Clinical and Translational Neurology. -
Differential Effects of Pathological Beta Burst Dynamics Between Parkinson's Disease Phenotypes Across Different Movements.
Neuville, R. S., Petrucci, M. N., Wilkins, K. B., Anderson, R. W., Hoffman, S. L., Parker, J. E., … Bronte-Stewart, H. M. (2021). Differential Effects of Pathological Beta Burst Dynamics Between Parkinson's Disease Phenotypes Across Different Movements. Frontiers in Neuroscience, 15, 733203. -
Data-Driven Prediction of Freezing of Gait Events From Stepping Data.
Parakkal Unni, M., Menon, P. P., Livi, L., Wilson, M. R., Young, W. R., Bronte-Stewart, H. M., & Tsaneva-Atanasova, K. (2020). Data-Driven Prediction of Freezing of Gait Events From Stepping Data. Frontiers in Medical Technology, 2, 581264. -
Assessing inertial measurement unit locations for freezing of gait detection and patient preference.
O'Day, J., Lee, M., Seagers, K., Hoffman, S., Jih-Schiff, A., Kidzinski, L., … Bronte-Stewart, H. (2022). Assessing inertial measurement unit locations for freezing of gait detection and patient preference. Journal of Neuroengineering and Rehabilitation, 19(1), 20. -
Concurrent stimulation and sensing in bi-directional brain interfaces: a multi-site translational experience.
Ansó, J., Benjaber, M., Parks, B., Parker, S., Oehrn, C. R., Petrucci, M., … Denison, T. J. (2022). Concurrent stimulation and sensing in bi-directional brain interfaces: a multi-site translational experience. Journal of Neural Engineering. -
Neurofunctional characteristics of executive control in older people with HIV infection: a comparison with Parkinson's disease.
Müller-Oehring, E. M., Hong, J.-Y. Y., Poston, K. L., Brontë-Stewart, H. M., Sullivan, E. V., McGlynn, L., & Schulte, T. (2022). Neurofunctional characteristics of executive control in older people with HIV infection: a comparison with Parkinson's disease. Brain Imaging and Behavior. -
Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury.
Wong, J. K., Deuschl, G., Wolke, R., Bergman, H., Muthuraman, M., Groppa, S., … Okun, M. S. (2022). Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury. Frontiers in Human Neuroscience, 16, 813387. -
Ramp Rate Evaluation and Configuration for Safe and Tolerable Closed-Loop Deep Brain Stimulation.
Petrucci, M. N., Wilkins, K. B., Orthlieb, G. C., Kehnemouyi, Y. M., O'Day, J. J., Herron, J. A., & Bronte-Stewart, H. M. (2021). Ramp Rate Evaluation and Configuration for Safe and Tolerable Closed-Loop Deep Brain Stimulation. International IEEE/EMBS Conference on Neural Engineering : [Proceedings]. International IEEE EMBS Conference on Neural Engineering, 2021, 959–962. -
Quantitative Digitography Measures Motor Symptoms and Disease Progression in Parkinson's Disease.
Wilkins, K. B., Petrucci, M. N., Kehnemouyi, Y., Velisar, A., Han, K., Orthlieb, G., … Bronte-Stewart, H. (2022). Quantitative Digitography Measures Motor Symptoms and Disease Progression in Parkinson's Disease. Journal of Parkinson's Disease. -
Bradykinesia and its progression are related to inter-hemispheric beta coherence.
Wilkins, K. B., Kehnemouyi, Y. M., Petrucci, M. N., Anderson, R. W., Parker, J. E., Trager, M. H., … Bronte-Stewart, H. M. (2023). Bradykinesia and its progression are related to inter-hemispheric beta coherence. Annals of Neurology. -
Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation.
Wong, J. K., Mayberg, H. S., Wang, D. D., Richardson, R. M., Halpern, C. H., Krinke, L., … Okun, M. S. (2022). Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation. Frontiers in Human Neuroscience, 16, 1084782. -
Episodic memory deficit in HIV infection: common phenotype with Parkinson's disease, different neural substrates.
Fama, R., Müller-Oehring, E. M., Levine, T. F., Sullivan, E. V., Sassoon, S. A., Asok, P., … Schulte, T. (2023). Episodic memory deficit in HIV infection: common phenotype with Parkinson's disease, different neural substrates. Brain Structure & Function. -
The Sequence Effect Worsens Over Time in Parkinson's Disease and Responds to Open and Closed-Loop Subthalamic Nucleus Deep Brain Stimulation.
Kehnemouyi, Y. M., Petrucci, M. N., Wilkins, K. B., Melbourne, J. A., & Bronte-Stewart, H. M. (2023). The Sequence Effect Worsens Over Time in Parkinson's Disease and Responds to Open and Closed-Loop Subthalamic Nucleus Deep Brain Stimulation. Journal of Parkinson's Disease. -
Hope vs. Hype: Closed loop technology will provide more meaningful improvement vs. directional leads in deep brain stimulation.
Bronte-Stewart, H., & Merola, A. (2023). Hope vs. Hype: Closed loop technology will provide more meaningful improvement vs. directional leads in deep brain stimulation. Parkinsonism & Related Disorders, 105452. -
Kinematic adaptive deep brain stimulation for gait impairment and freezing of gait in Parkinson's disease.
Melbourne, J. A., Kehnemouyi, Y. M., O'Day, J. J., Wilkins, K. B., Gala, A. S., Petrucci, M. N., … Bronte-Stewart, H. M. (2023). Kinematic adaptive deep brain stimulation for gait impairment and freezing of gait in Parkinson's disease. Brain Stimulation. -
No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment.
Crockett, R. A., Wilkins, K. B., Aditham, S., & Brontë-Stewart, H. M. (2023). No laughing white matter: Reduced integrity of the cortical cholinergic pathways in Parkinson's disease-related cognitive impairment. Neurobiology of Disease, 106243. -
No Laughing White Matter: Cortical Cholinergic Pathways and Cognitive Decline in Parkinson's Disease.
Crockett, R. A., Wilkins, K. B., Aditham, S., & Brontë-Stewart, H. M. (2023). No Laughing White Matter: Cortical Cholinergic Pathways and Cognitive Decline in Parkinson's Disease. MedRxiv : the Preprint Server for Health Sciences. -
Transcutaneous Afferent Patterned Stimulation for Essential Tremor: Real-World Evidence with Long Term Follow-Up.
Lu, C., Khosla, D., Kent, A., Bronte-Stewart, H. M., & Rosenbluth, K. H. (2023). Transcutaneous Afferent Patterned Stimulation for Essential Tremor: Real-World Evidence with Long Term Follow-Up. Tremor and Other Hyperkinetic Movements (New York, N.Y.), 13, 29. -
An Individualized Tractography Pipeline for the Nucleus Basalis of Meynert Lateral Tract.
Crockett, R. A., Wilkins, K. B., Zeineh, M. M., McNab, J. A., Henderson, J. M., Buch, V. P., & Brontë-Stewart, H. M. (2023). An Individualized Tractography Pipeline for the Nucleus Basalis of Meynert Lateral Tract. MedRxiv : the Preprint Server for Health Sciences. -
Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease: ADAPT-PD clinical trial methodology and early data
Bronte-Stewart, H., Beudel, M., Ostrem, J. L., Fasano, A., Almeida, L., Hassell, T., … Herrington, T. M. (2023). Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease: ADAPT-PD clinical trial methodology and early data. NEUROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
The Effect of Deep Brain Stimulation on the Sequence Effect in Speech in Parkinson's Disease
Je, G., Wilkins, K. B., Melbourne, J. A., & Bronte-Stewart, H. M. (2023). The Effect of Deep Brain Stimulation on the Sequence Effect in Speech in Parkinson's Disease. ANNALS OF NEUROLOGY. WILEY. -
Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study.
Schiff, N. D., Giacino, J. T., Butson, C. R., Choi, E. Y., Baker, J. L., O'Sullivan, K. P., … Henderson, J. M. (2023). Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study. Nature Medicine. -
Unraveling the complexities of programming neural adaptive deep brain stimulation in Parkinson's disease.
Wilkins, K. B., Melbourne, J. A., Akella, P., & Bronte-Stewart, H. M. (2023). Unraveling the complexities of programming neural adaptive deep brain stimulation in Parkinson's disease. Frontiers in Human Neuroscience, 17, 1310393. -
Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements.
Johnson, K. A., Dosenbach, N. U., Gordon, E. M., Welle, C. G., Wilkins, K. B., Bronte-Stewart, H. M., … Wong, J. K. (2024). Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for adaptive DBS, bioethical dilemmas, AI-guided neuromodulation, and translational advancements. Frontiers in Human Neuroscience, 18, 1320806. -
Comprehensive real time remote monitoring for Parkinson's disease using Quantitative DigitoGraphy.
Hoffman, S. L., Schmiedmayer, P., Gala, A. S., Wilkins, K. B., Parisi, L., Karjagi, S., … Bronte-Stewart, H. (2024). Comprehensive real time remote monitoring for Parkinson's disease using Quantitative DigitoGraphy. NPJ Parkinson's Disease, 10(1), 137. -
Lateral Thinking: Pathway Specific Neurodegeneration of the Cortical Cholinergic System in Alzheimer's Disease.
Crockett, R. A., Casselton, C., Howard, T. M., Wilkins, K. B., Seo, G., & Brontë-Stewart, H. M. (2024). Lateral Thinking: Pathway Specific Neurodegeneration of the Cortical Cholinergic System in Alzheimer's Disease. MedRxiv : the Preprint Server for Health Sciences. -
The digital signature of emergent tremor in Parkinson's disease.
Gala, A. S., Wilkins, K. B., Petrucci, M. N., Kehnemouyi, Y. M., Velisar, A., Trager, M. H., & Bronte-Stewart, H. M. (2024). The digital signature of emergent tremor in Parkinson's disease. NPJ Parkinson's Disease, 10(1), 147. -
Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) clinical trial.
Stanslaski, S., Summers, R. L., Tonder, L., Tan, Y., Case, M., Raike, R. S., … Bronte-Stewart, H. (2024). Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) clinical trial. NPJ Parkinson's Disease, 10(1), 174. -
Lateral thinking: Neurodegeneration of the cortical cholinergic system in Alzheimer's disease.
Crockett, R. A., Casselton, C., Howard, T. M., Wilkins, K. B., Seo, G., & Brontë-Stewart, H. M. (2024). Lateral thinking: Neurodegeneration of the cortical cholinergic system in Alzheimer's disease. Neurobiology of Disease, 106677.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
Practice Locations
Stanford Neuroscience Health Center Palo Alto, CA
Palo Alto, CA
Stanford Neuroscience Health Center
213 Quarry Road
Palo Alto , CA 94304
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Movement Disorders Program in Palo Alto
213 Quarry Road
Palo Alto , CA 94304
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Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Patient Reviews
(55 reviews)
Excellent
I'm happy working with Dr Bronte-Stewart, look forward to a continuing relationship.
Dr Brontë-Stewart is a blessing to anyone who is lucky enough to be her patient.
She has tremendous care for her patients as well as experience and knowledge.
Everything from check in to my visit with the amazing Dr Helen Bronte-Stewart was outstanding!
DR bronte Steward and her team are the BEST
The best!
Dr. Bronte-Stewart was exceptional in helping me understand my disease.
XCEPTOINAL SERVICE
She is an excellent doctor, patient, caring, and thorough
Dr. Helen Bronte Stewart is an exceptional physician.
I recommend Dr. Bronte-Stewart unreservedly. Her comprehensive care has invariably been for the person, as well as the disease.
Dr. Helen Bronte Stewart is an exception doctor. I am grateful she is my doc.
Never felt rushed.
This care provider is outstanding.
Dr. Bronte-Stewart is truly wonderful in every way.
It is always a pleasure to see Dr. Bronte-Stewart @ clinic. She is very warm & engaging, professional, knowledgeable, helpful & supportive.
Dr. Bronte-Stewart always takes the time to thoroughly go over my case and changes/updates on my care.
Dr. was very patient in spite of time crunch.
Dr. Bronte-Stewart is the most engaged, attentive physician I have ever had. I feel lucky to be her patient.
Excellent!!
My problems has not resolve.
Extraordinary doctor!
She is always excellent.
Dr. B-S is awesome - she and I go way back.
Dr. Bronte-Stewart is an extraordinary doctor. Brilliant, knowledgeable, attentive, compassionate. We have been working with her for over 16 yrs.
Dr. Bronte-Stewart is an exceptional physician!
Dr. Bronte-Stewart is an excellent clinician - I recommend her to all my fellow PD patients.
Dr. Bronte-Stewart was wonderful - Very efficient and informative.
Dr. Helen Bronte-Stewart is my doctor for Parkinson's & she is excellent.
Dr. Bronte-Stewart is an excellent doctor.
Dr. Bronte-Stewart is the best! Dr. Haul was very good - excellent.
We love Dr. Helen Bronte-Stewart! She has been our dr. since 2006. We always recommend Stanford & even when not related to DBS reassure friends that Stanford is the best place to be!
This doctor is truly EXCEPTIONAL.
Always pleasant & helpful.
Helen Bronte-Stewart provides unimaginably good service, explanation, and care.
Dr. Bronte-Stewart is simply the finest physician I have known.
Always a good experience.
Dr. Bronte-Stewart is a treasure. Hold on to her.
Great pleasure to work with both Dr. Bronte-Stewart and the first doctor that spent a long time with me and was very thorough.
Dr. Bronte-Stewart is the best.
Very caring individual recommended a friend to this doctor.
I have Parkinsons. I've been seeing Dr.Bronte-Stewart twice a year for 15 years. I couldn't be more grateful for her care.
The care providers were BETTER than very good - truly exceptional.
Dr. Bronte-Stewart and her NP, Lauren, were terrific! Patient, focused, caring, did not rush & extremely thorough.
Staff always courteous & professional.
Dr. Bronte-Stewart is excellent! She gives good explanations and has taken time to get to know me well.
Dr. Poston & Carlos Rodriguez were attempting to me - the very best!
I cannot say enough positive things about both the fellow & Dr Bronte-Stewart...
Good.
Very good.
Never felt rushed - she was very thorough.
Absolutely the perfect physician.
Good experience - Dr. Bronte-Stewart staff are current on my symptoms and medications.
No problem.
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