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![Michael Fischbein](/content/dam/SHC/doctors-medicalstaff/f/fischbein-michael-md.jpg/_jcr_content/renditions/original.transform/280x280-q76/image.jpg)
Professional Summary
Education & Certifications
- Board Certification: American Board of Thoracic Surgery, Thoracic and Cardiac Surgery (2007)
- Medical Education: Boston University School of Medicine (1995) MA
- PhD Training: University of California Los Angeles (2001) CA
- Fellowship: Stanford University Dept of Cardiothoracic Surgery (2006) CA
- Residency: UCLA General Surgery Residency (2003) CA
- PhD, University of California, Los Angeles, Microbiology and Immunology (2001)
- MD, Boston University School of Medicine, Medicine - Cum Laude (1995)
- BS, University of California, Los Angeles, Kinesiology (1990)
Honors & Awards
- Alpha Omega Alpha, Boston University School of Medicine (1994)
- Caves Scientific Award, International Society for Heart and Lung Transplantation - Osaka, Japan (2000)
- Cum Laude Graduate, Boston University School of Medicine (1995)
- Donald Morton Research Award, Department of Surgery - UCLA School of Medicine (2003)
- Golden Scalpel Award for Teaching Excellence, Division of General Surgery - UCLA School of Medicine (2003)
- Ronald K. Tompkins Golden Apple Teaching Award, UCLA School of Medicine (2003)
Publications
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Stem cell transplantation: The lung barrier
Schrepfer, S., Deuse, T., Reichenspurner, H., Fischbein, M. P., Robbins, R. C., & Pelletier, M. P. (2007). Stem cell transplantation: The lung barrier. TRANSPLANTATION PROCEEDINGS, 39(2), 573–576. -
Effect of inhaled tacrolimus on cellular and humoral rejection to prevent posttransplant obliterative airway disease
Schrepfer, S., Deuse, T., Reichenspurner, H., Hoffmann, J., Haddad, M., Fink, J., … Pelletier, M. P. (2007). Effect of inhaled tacrolimus on cellular and humoral rejection to prevent posttransplant obliterative airway disease. AMERICAN JOURNAL OF TRANSPLANTATION, 7(7), 1733–1742. -
Comparison of different adult stem cell types for treatment of myocardial ischemia
van der Bogt, K. E. A., Sheikh, A. Y., Schrepfer, S., Hoyt, G., Cao, F., Ransohoff, K. J., … Wu, J. C. (2008). Comparison of different adult stem cell types for treatment of myocardial ischemia. CIRCULATION. ORLANDO,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL: LIPPINCOTT WILLIAMS & WILKINS. -
Long-Term Durability of Open Thoracic and Thoracoabdominal Aneurysm Repair
Fischbein, M. P., & Miller, D. C. (2009). Long-Term Durability of Open Thoracic and Thoracoabdominal Aneurysm Repair. SEMINARS IN VASCULAR SURGERY, 22(2), 74–80. -
The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice
Itoh, S., Nakae, S., Velotta, J. B., Kosuge, H., Connolly, A., Tsai, M., … Fischbein, M. P. (2010). The role of recipient mast cells in acute and chronic cardiac allograft rejection in C57BL/6-KitW-sh/W-sh mice. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 29(4), 401–9. -
IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model
Itoh, S., Nakae, S., Axtell, R. C., Velotta, J. B., Kimura, N., Kajiwara, N., … Fischbein, M. P. (2010). IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model. JOURNAL OF CLINICAL IMMUNOLOGY, 30(2), 235–40. -
Micro-CT for Characterization of Murine CV Disease Models
Sheikh, A. Y., van der Bogt, K. E. A., Doyle, T. C., Sheikh, M. K., Ransohoff, K. J., Ali, Z. A., … Wu, J. C. (2010). Micro-CT for Characterization of Murine CV Disease Models. JACC-CARDIOVASCULAR IMAGING, 3(7), 783–85. -
"Peninsula- Style" Transverse Aortic Arch Replacement in Patients With Bicuspid Aortic Valve
Itoh, A., Fischbein, M., Arata, K., & Miller, D. C. (2010). "Peninsula- Style" Transverse Aortic Arch Replacement in Patients With Bicuspid Aortic Valve. ANNALS OF THORACIC SURGERY, 90(4), 1369–71. -
RevaTen platelet-rich plasma improves cardiac function after myocardial injury.
Mishra, A., Velotta, J., Brinton, T. J., Wang, X., Chang, S., Palmer, O., … Fischbein, M. (2011). RevaTen platelet-rich plasma improves cardiac function after myocardial injury. Cardiovascular Revascularization Medicine : Including Molecular Interventions, 12(3), 158–63. -
Prevention of transplant coronary artery disease by prenylation inhibitors
Stein, W., Schrepfer, S., Itoh, S., Kimura, N., Velotta, J., Palmer, O., … Fischbein, M. P. (2011). Prevention of transplant coronary artery disease by prenylation inhibitors. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 30(7), 761–69. -
alpha B-Crystallin Improves Murine Cardiac Function and Attenuates Apoptosis in Human Endothelial Cells Exposed to Ischemia-Reperfusion
Velotta, J. B., Kimura, N., Chang, S. H., Chung, J., Itoh, S., Rothbard, J., … Fischbein, M. P. (2011). alpha B-Crystallin Improves Murine Cardiac Function and Attenuates Apoptosis in Human Endothelial Cells Exposed to Ischemia-Reperfusion. ANNALS OF THORACIC SURGERY, 91(6), 1907–13. -
Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion
Itoh, S., Kimura, N., Axtell, R. C., Velotta, J. B., Gong, Y., Wang, X., … Fischbein, M. P. (2011). Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion. CIRCULATION. CHICAGO,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL,IL: LIPPINCOTT WILLIAMS & WILKINS. -
In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium
Sheikh, A. Y., Huber, B. C., Narsinh, K. H., Spin, J. M., van der Bogt, K., de Almeida, P. E., … Wu, J. C. (2012). In Vivo Functional and Transcriptional Profiling of Bone Marrow Stem Cells After Transplantation Into Ischemic Myocardium. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 32(1), 92–102. -
Interleukin-16 deficiency suppresses the development of chronic rejection in murine cardiac transplantation model
Kimura, N., Itoh, S., Nakae, S., Axtell, R. C., Velotta, J. B., Bos, E. J., … Fischbein, M. P. (2011). Interleukin-16 deficiency suppresses the development of chronic rejection in murine cardiac transplantation model. JOURNAL OF HEART AND LUNG TRANSPLANTATION, 30(12), 1409–17. -
miR-29b Participates in Early Aneurysm Development in Marfan Syndrome
Merk, D. R., Chin, J. T., Dake, B. A., Maegdefessel, L., Miller, M. O., Kimura, N., … Fischbein, M. P. (2012). miR-29b Participates in Early Aneurysm Development in Marfan Syndrome. CIRCULATION RESEARCH, 110(2), 312-? -
A novel cardioprotective agent in cardiac transplantation: metformin activation of AMP-activated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection.
Chin, J. T., Troke, J. J., Kimura, N., Itoh, S., Wang, X., Palmer, O. P., … Fischbein, M. P. (2011). A novel cardioprotective agent in cardiac transplantation: metformin activation of AMP-activated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection. Yale Journal of Biology and Medicine, 84(4), 423–32. -
Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Disease
van der Bogt, K. E. A., Hellingman, A. A., Lijkwan, M. A., Bos, E.-J., de Vries, M. R., van Rappard, J. R. M., … Wu, J. C. (2012). Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Disease. JACC-CARDIOVASCULAR IMAGING, 5(1), 46–55. -
Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement
Kodali, S. K., Williams, M. R., Smith, C. R., Svensson, L. G., Webb, J. G., Makkar, R. R., … Leon, M. B. (2012). Two-Year Outcomes after Transcatheter or Surgical Aortic-Valve Replacement. NEW ENGLAND JOURNAL OF MEDICINE, 366(18), 1686–95. -
Potential Role of gamma delta T Cell-Derived IL-17 in Acute Cardiac Allograft Rejection
Kimura, N., Nakae, S., Itoh, S., Merk, D. R., Wang, X., Gong, Y., … Fischbein, M. P. (2012). Potential Role of gamma delta T Cell-Derived IL-17 in Acute Cardiac Allograft Rejection. ANNALS OF THORACIC SURGERY, 94(2), 542–48. -
Bicuspid aortic valve configuration and aortopathy pattern might represent different pathophysiologic substrates
Kari, F. A., Fazel, S. S., Mitchell, R. S., Fischbein, M. P., & Miller, D. C. (2012). Bicuspid aortic valve configuration and aortopathy pattern might represent different pathophysiologic substrates. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 144(2), 516–17. -
David valve-sparing aortic root replacement: Equivalent mid-term outcome for different valve types with or without connective tissue disorder
Kvitting, J.-P. E., Kari, F. A., Fischbein, M. P., Liang, D. H., Beraud, A.-S., Stephens, E. H., … Miller, D. C. (2013). David valve-sparing aortic root replacement: Equivalent mid-term outcome for different valve types with or without connective tissue disorder. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 145(1), 117-? -
Tirone David valve-sparing aortic root replacement and cusp repair for bicuspid aortic valve disease
Kari, F. A., Liang, D. H., Kvitting, J.-P. E., Stephens, E. H., Mitchell, R. S., Fischbein, M. P., & Miller, D. C. (2013). Tirone David valve-sparing aortic root replacement and cusp repair for bicuspid aortic valve disease. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 145(3), S35-? -
Open aortic valve replacement in a patient with Glanzmann's thrombasthenia: a multidisciplinary strategy to minimize perioperative bleeding.
Sheikh, A. Y., Hill, C. C., Goodnough, L. T., Leung, L. L., & Fischbein, M. P. (2014). Open aortic valve replacement in a patient with Glanzmann's thrombasthenia: a multidisciplinary strategy to minimize perioperative bleeding. Transfusion, 54(2), 300–305. -
COMPUTED TOMOGRAPHY BASED PREDICTION OF ANGIOGRAPHIC DEPLOYMENT ANGLES MAY REDUCE PROCEDURE TIME AND CONTRAST MEDIUM VOLUME FOR TRANSCATHETER AORTIC VALVE REPLACEMENT
Fleischmann, D., Dao, C., Blake, T., Boas, F. E., Liang, D., Yeung, A., … Miller, D. C. (2012). COMPUTED TOMOGRAPHY BASED PREDICTION OF ANGIOGRAPHIC DEPLOYMENT ANGLES MAY REDUCE PROCEDURE TIME AND CONTRAST MEDIUM VOLUME FOR TRANSCATHETER AORTIC VALVE REPLACEMENT. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 59(13), E1199–E1199. -
AORTIC WALL THICKNESS MAY BE AN INDEPENDENT RISK FACTOR FOR AORTIC DISSECTION
Shiran, H., Odegaard, J., Berry, G., Miller, D. C., Fischbein, M., & Liang, D. (2012). AORTIC WALL THICKNESS MAY BE AN INDEPENDENT RISK FACTOR FOR AORTIC DISSECTION. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 59(13), E831–E831. -
ACCURACY AND REPRODUCIBILITY OF CONTRAST ENHANCED AND NON-ENHANCED COMPUTED TOMOGRAPHY FOR PREDICTING THE ANGIOGRAPHIC DEPLOYMENT ANGLE IN TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Dao, C. N., Blake, T., Liang, D., Fischbein, M. P., Yeung, A., Fearon, W., … Fleischmann, D. (2012). ACCURACY AND REPRODUCIBILITY OF CONTRAST ENHANCED AND NON-ENHANCED COMPUTED TOMOGRAPHY FOR PREDICTING THE ANGIOGRAPHIC DEPLOYMENT ANGLE IN TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR). JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 59(13), E1195–E1195. -
Exogenous aB-crystallin Improves Myocardial Function and Attenuates Apoptosis in Ischemia-Reperfusion Injury
Chang, S. H., Velotta, J. B., Chung, J., Itoh, S., Rothbard, J. B., Yang, P. C., … Fischbein, M. P. (2009). Exogenous aB-crystallin Improves Myocardial Function and Attenuates Apoptosis in Ischemia-Reperfusion Injury. CIRCULATION. ORLANDO,FL,FL,FL,FL,FL,FL,FL,FL,FL,FL: LIPPINCOTT WILLIAMS & WILKINS. -
Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion
Itoh, S., Kimura, N., Nakae, S., Axtell, R. C., Velotta, J. B., Wang, X., … Fischbein, M. P. (2010). Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion. CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. -
Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model?
Deuse, T., Schrepfer, S., Reichenspurner, H., Hoyt, G., Fischbein, M. P., Robbins, R. C., & Pelletier, M. P. (2007). Techniques for experimental heterotopic and orthotopic tracheal transplantations - When to use which model? TRANSPLANT IMMUNOLOGY, 17(4), 255–261. -
Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection?
Deuse, T., Schrepfer, S., Pelletier, M. P., Fischbein, M. P., Robbins, R. C., & Reichenspurner, H. (2007). Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection? TRANSPLANTATION PROCEEDINGS, 39(2), 569–572. -
A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation.
Khatri, P., Roedder, S., Kimura, N., De Vusser, K., Morgan, A. A., Gong, Y., … Sarwal, M. M. (2013). A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation. Journal of Experimental Medicine, 210(11), 2205–21. -
Incidence and progression of mild aortic regurgitation after Tirone David reimplantation valve-sparing aortic root replacement
Stephens, E. H., Liang, D. H., Kvitting, J.-P. E., Kari, F. A., Fischbein, M. P., Mitchell, R. S., & Miller, D. C. (2014). Incidence and progression of mild aortic regurgitation after Tirone David reimplantation valve-sparing aortic root replacement. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 147(1), 169-? -
Assessment of elastin deficit in a marfan mouse aneurysm model using an elastin-specific magnetic resonance imaging contrast agent.
Okamura, H., Pisani, L. J., Dalal, A. R., Emrich, F., Dake, B. A., Arakawa, M., … Fischbein, M. P. (2014). Assessment of elastin deficit in a marfan mouse aneurysm model using an elastin-specific magnetic resonance imaging contrast agent. Circulation. Cardiovascular Imaging, 7(4), 690–96. -
Tirone David procedure for bicuspid aortic valve disease: impact of root geometry and valve type on mid-term outcomes†.
Kari, F. A., Kvitting, J.-P. E., Stephens, E. H., Liang, D. H., Merk, D. R., Fischbein, M. P., … Miller, D. C. (2014). Tirone David procedure for bicuspid aortic valve disease: impact of root geometry and valve type on mid-term outcomes†. Interactive Cardiovascular and Thoracic Surgery, 19(3), 375–81. -
Aortic wall thickness: an independent risk factor for aortic dissection?
Shiran, H., Odegaard, J., Berry, G., Miller, D. C., Fischbein, M., & Liang, D. (2014). Aortic wall thickness: an independent risk factor for aortic dissection? Journal of Heart Valve Disease, 23(1), 17–24. -
Outcomes After Transfemoral Transcatheter Aortic Valve Replacement A Comparison of the Randomized PARTNER (Placement of AoRTic TraNscathetER Valves) Trial With the NRCA (Nonrandomized Continued Access) Registry
Fearon, W. F., Kodali, S., Doshi, D., Fischbein, M. P., Yeung, A. C., Tuzcu, E. M., … Leon, M. B. (2014). Outcomes After Transfemoral Transcatheter Aortic Valve Replacement A Comparison of the Randomized PARTNER (Placement of AoRTic TraNscathetER Valves) Trial With the NRCA (Nonrandomized Continued Access) Registry. JACC-CARDIOVASCULAR INTERVENTIONS, 7(11), 1245–51. -
Enhanced Caspase Activity Contributes to Aortic Wall Remodeling and Early Aneurysm Development in a Murine Model of Marfan Syndrome
Emrich, F. C., Okamura, H., Dalal, A. R., Penov, K., Merk, D. R., Raaz, U., … Fischbein, M. P. (2015). Enhanced Caspase Activity Contributes to Aortic Wall Remodeling and Early Aneurysm Development in a Murine Model of Marfan Syndrome. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 35(1), 146–54. -
The relative performance characteristics of the logistic European System for Cardiac Operative Risk Evaluation score and the Society of Thoracic Surgeons score in the Placement of Aortic Transcatheter Valves trial.
Beohar, N., Whisenant, B., Kirtane, A. J., Leon, M. B., Tuzcu, E. M., Makkar, R., … Mack, M. (2014). The relative performance characteristics of the logistic European System for Cardiac Operative Risk Evaluation score and the Society of Thoracic Surgeons score in the Placement of Aortic Transcatheter Valves trial. Journal of Thoracic and Cardiovascular Surgery, 148(6), 2830–37 e1. -
The relative performance characteristics of the logistic European System for Cardiac Operative Risk Evaluation score and the Society of Thoracic Surgeons score in the Placement of Aortic Transcatheter Valves trial
Beohar, N., Whisenant, B., Kirtane, A. J., Leon, M. B., Tuzcu, E. M., Makkar, R., … Mack, M. (2014). The relative performance characteristics of the logistic European System for Cardiac Operative Risk Evaluation score and the Society of Thoracic Surgeons score in the Placement of Aortic Transcatheter Valves trial. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 148(6), 2830–U1495. -
Outcomes after transfemoral transcatheter aortic valve replacement: a comparison of the randomized PARTNER (Placement of AoRTic TraNscathetER Valves) trial with the NRCA (Nonrandomized Continued Access) registry.
Fearon, W. F., Kodali, S., Doshi, D., Fischbein, M. P., Yeung, A. C., Tuzcu, E. M., … Leon, M. B. (2014). Outcomes after transfemoral transcatheter aortic valve replacement: a comparison of the randomized PARTNER (Placement of AoRTic TraNscathetER Valves) trial with the NRCA (Nonrandomized Continued Access) registry. JACC. Cardiovascular Interventions, 7(11), 1245–51. -
Midterm Outcomes of Open Descending Thoracic Aortic Repair in More Than 5,000 Medicare Patients
Schaffer, J. M., Lingala, B., Fischbein, M. P., Dake, M. D., Woo, Y. J., Mitchell, R. S., & Miller, D. C. (2015). Midterm Outcomes of Open Descending Thoracic Aortic Repair in More Than 5,000 Medicare Patients. ANNALS OF THORACIC SURGERY, 100(6), 2087–94. -
Salvage Extracorporeal Membrane Oxygenation Prior to "Bridge" Transcatheter Aortic Valve Replacement.
Chiu, P., Fearon, W. F., Raleigh, L. A., Burdon, G., Rao, V., Boyd, J. H., … Fischbein, M. P. (2016). Salvage Extracorporeal Membrane Oxygenation Prior to "Bridge" Transcatheter Aortic Valve Replacement. Journal of Cardiac Surgery, 31(6), 403–5. -
Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients
Leon, M. B., Smith, C. R., Mack, M. J., Makkar, R. R., Svensson, L. G., Kodali, S. K., … Webb, J. G. (2016). Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients. NEW ENGLAND JOURNAL OF MEDICINE, 374(17), 1609–20. -
Dual-Modality Activity-Based Probes as Molecular Imaging Agents for Vascular Inflammation
Withana, N. P., Saito, T., Ma, X., Garland, M., Liu, C., Kosuge, H., … Bogyo, M. (2016). Dual-Modality Activity-Based Probes as Molecular Imaging Agents for Vascular Inflammation. JOURNAL OF NUCLEAR MEDICINE, 57(10), 1583–90. -
Surgical Unroofing of Hemodynamically Significant Left Anterior Descending Myocardial Bridges.
Boyd, J. H., Pargaonkar, V. S., Scoville, D. H., Rogers, I. S., Kimura, T., Tanaka, S., … Schnittger, I. (2016). Surgical Unroofing of Hemodynamically Significant Left Anterior Descending Myocardial Bridges. Annals of Thoracic Surgery. -
Giant saphenous vein graft aneurysm compressing the lingular bronchus.
Chiu, P., Palmon, I., & Fischbein, M. P. (2016). Giant saphenous vein graft aneurysm compressing the lingular bronchus. Journal of Thoracic and Cardiovascular Surgery. -
Branched Endovascular Therapy of the Distal Aortic Arch: Preliminary Results of the Feasibility Multicenter Trial of the Gore Thoracic Branch Endoprosthesis.
Patel, H. J., Dake, M. D., Bavaria, J. E., Singh, M. J., Filinger, M., Fischbein, M. P., … Oderich, G. (2016). Branched Endovascular Therapy of the Distal Aortic Arch: Preliminary Results of the Feasibility Multicenter Trial of the Gore Thoracic Branch Endoprosthesis. Annals of Thoracic Surgery, 102(4), 1190–98. -
Computed Tomography Imaging Features in Acute Uncomplicated Stanford Type-B Aortic Dissection Predict Late Adverse Events
Sailer, A. M., Van Kuijk, S. M. J., Nelemans, P. J., Chin, A. S., Kino, A., Huininga, M., … Fleischmann, D. (2017). Computed Tomography Imaging Features in Acute Uncomplicated Stanford Type-B Aortic Dissection Predict Late Adverse Events. CIRCULATION-CARDIOVASCULAR IMAGING, 10(4). -
Dynamic changes in aortic impedance after transcatheter aortic valve replacement and its impact on exploratory outcome.
Kobayashi, Y., Kim, J. B., Moneghetti, K. J., Kobayashi, Y., Zhang, R., Brenner, D. A., … Fearon, W. F. (2017). Dynamic changes in aortic impedance after transcatheter aortic valve replacement and its impact on exploratory outcome. International Journal of Cardiovascular Imaging. -
Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model.
Okamura, H., Emrich, F., Trojan, J., Chiu, P., Dalal, A. R., Arakawa, M., … Fischbein, M. P. (2017). Long-term miR-29b suppression reduces aneurysm formation in a Marfan mouse model. Physiological Reports, 5(8). -
Gene expression profiling of acute type A aortic dissection combined with in vitroassessment†.
Kimura, N., Futamura, K., Arakawa, M., Okada, N., Emrich, F., Okamura, H., … Fischbein, M. P. (2017). Gene expression profiling of acute type A aortic dissection combined with in vitroassessment†. European Journal of Cardio-Thoracic Surgery . -
Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement.
Goldstone, A. B., Chiu, P., Baiocchi, M., Lingala, B., Patrick, W. L., Fischbein, M. P., & Woo, Y. J. (2017). Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement. The New England Journal of Medicine, 377(19), 1847–57. -
Limited root repair in acute type A aortic dissection is safe but results in increased risk of reoperation.
Chiu, P., Trojan, J., Tsou, S., Goldstone, A. B., Woo, Y. J., & Fischbein, M. P. (2017). Limited root repair in acute type A aortic dissection is safe but results in increased risk of reoperation. The Journal of Thoracic and Cardiovascular Surgery. -
Prognostic significance of early aortic remodeling in acute uncomplicated type B aortic dissection and intramural hematoma.
Sailer, A. M., Nelemans, P. J., Hastie, T. J., Chin, A. S., Huininga, M., Chiu, P., … Fleischmann, D. (2017). Prognostic significance of early aortic remodeling in acute uncomplicated type B aortic dissection and intramural hematoma. The Journal of Thoracic and Cardiovascular Surgery, 154(4), 1192–1200. -
GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement.
Kim, J. B., Kobayashi, Y., Moneghetti, K. J., Brenner, D. A., O'Malley, R., Schnittger, I., … Fearon, W. F. (2017). GDF-15 (Growth Differentiation Factor 15) Is Associated With Lack of Ventricular Recovery and Mortality After Transcatheter Aortic Valve Replacement. Circulation. Cardiovascular Interventions, 10(12). -
Impact of Discordant Views in the Management of Descending Thoracic Aortic Aneurysm
Chiu, P., Sailer, A.-M., Baiocchi, M., Goldstone, A. B., Schaffer, J. M., Trojan, J., … Fischbein, M. P. (2017). Impact of Discordant Views in the Management of Descending Thoracic Aortic Aneurysm. SEMINARS IN THORACIC AND CARDIOVASCULAR SURGERY, 29(3), 283–91. -
SINGLE-CENTER ACUTE AORTIC SYNDROME REGISTRY: A 10-YEAR EXPERIENCE OF "CLASS 3" LIMITED DISSECTION OF THE AORTA
Chin, A. S., Kino, A., Berry, G., Rosenberg, J., Fischbein, M., Miller, D. C., & Fleischmann, D. (2014). SINGLE-CENTER ACUTE AORTIC SYNDROME REGISTRY: A 10-YEAR EXPERIENCE OF "CLASS 3" LIMITED DISSECTION OF THE AORTA. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 63(12), A1000. -
Poorer Left Ventricular Global Longitudinal Strain and Less Tricuspid Regurgitation Predicts Improvement in Left Ventricular Function Following Transcatheter Aortic Valve Replacement
Kim, J. B., Brenner, D., Kobayashi, Y., O'Malley, R., Kobayashi, Y., Dao, C., … Fearon, W. F. (2015). Poorer Left Ventricular Global Longitudinal Strain and Less Tricuspid Regurgitation Predicts Improvement in Left Ventricular Function Following Transcatheter Aortic Valve Replacement. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
Immediate operation for acute type A aortic dissection complicated by visceral or peripheral malperfusion.
Chiu, P., Tsou, S., Goldstone, A. B., Louie, M., Woo, Y. J., & Fischbein, M. P. (2018). Immediate operation for acute type A aortic dissection complicated by visceral or peripheral malperfusion. The Journal of Thoracic and Cardiovascular Surgery. -
THE RESUSCITATED NHBD HEART IS FUNCTIONALLY SUPERIOR TO THE BRAINSTEM DEAD DONOR HEART
Ali, A., Fajardo, G., Tsuda, S., Budas, G., Ali, Z., Quertermous, T., … Ashley, E. (2010). THE RESUSCITATED NHBD HEART IS FUNCTIONALLY SUPERIOR TO THE BRAINSTEM DEAD DONOR HEART. TRANSPLANT INTERNATIONAL, 23, 7. -
THE RESUSCITATED DECEASED DONOR HEART IS FUNCTIONALLY SUPERIOR TO THE BRAINSTEM DEAD DONOR HEART
Ali, A. A., Fajardo, G., Tsuda, S., Budas, G., Ali, Z., Quertermous, T., … Ashley, E. (2009). THE RESUSCITATED DECEASED DONOR HEART IS FUNCTIONALLY SUPERIOR TO THE BRAINSTEM DEAD DONOR HEART. TRANSPLANT INTERNATIONAL, 22, 138. -
Apoptosis Participates in Early Aneurysm Development via ECM Remodeling in Marfan Syndrome
Emrich, F. C., Okamura, H., Dalal, A. R., Merk, D. R., Raaz, U., Hennigs, J. K., … Fischbein, M. P. (2013). Apoptosis Participates in Early Aneurysm Development via ECM Remodeling in Marfan Syndrome. CIRCULATION, 128(22). -
PREDICTING MORTALITY WITH AORTOMITRAL CALCIFICATIONS IN 317 TAVR PATIENTS
Willemink, M., Maret, E., Moneghetti, K., Kim, J., Haddad, F., Kobayashi, Y., … Fleischmann, D. (2018). PREDICTING MORTALITY WITH AORTOMITRAL CALCIFICATIONS IN 317 TAVR PATIENTS. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
Two-stage surgical approach for ruptured Salmonella aortitis
Brewer, Z. E., Dake, M. D., & Fischbein, M. P. (2018). Two-stage surgical approach for ruptured Salmonella aortitis. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 155(3), E87–E89. -
Acute Limited Intimal Tears of the Thoracic Aorta.
Chin, A. S., Willemink, M. J., Kino, A., Hinostroza, V., Sailer, A. M., Fischbein, M. P., … Fleischmann, D. (2018). Acute Limited Intimal Tears of the Thoracic Aorta. Journal of the American College of Cardiology, 71(24), 2773–85. -
THE INFLAMMASOME PATHWAY IS ASSOCIATED WITH ADVERSE VENTRICULAR REMODELING FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT
Kim, J. B., Kobayashi, Y., Kouznetsova, T., Moneghetti, K., Brenner, D., O'Malley, R., … Haddad, F. (2017). THE INFLAMMASOME PATHWAY IS ASSOCIATED WITH ADVERSE VENTRICULAR REMODELING FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
Left Ventricular Ejection Fraction Improves Less after Trans-Apical Transcatheter Aortic Valve Replacement Compared to a Trans-Femoral Approach
Fearon, W. F., Elmariah, S., McAndrew, T., Vlahakes, G. J., Fischbein, M., Liang, D., … Miller, D. C. (2013). Left Ventricular Ejection Fraction Improves Less after Trans-Apical Transcatheter Aortic Valve Replacement Compared to a Trans-Femoral Approach. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 62(18), B36. -
Baseline growth differentiation factor 15 (GDF15) is an independent predictor of reverse left atrial remodeling and mortality at 1-year following Transcatheter Aortic Valve Replacement
Kim, J., Kobayashi, Y., Brenner, D., Moneghetti, K., O'Malley, R., Dao, C., … Fearon, W. (2016). Baseline growth differentiation factor 15 (GDF15) is an independent predictor of reverse left atrial remodeling and mortality at 1-year following Transcatheter Aortic Valve Replacement. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
Cytokines profile of reverse cardiac remodeling following transcatheter aortic valve replacement.
Kim, J. B., Kobayashi, Y., Kuznetsova, T., Moneghetti, K. J., Brenner, D. A., O'Malley, R., … Fearon, W. F. (2018). Cytokines profile of reverse cardiac remodeling following transcatheter aortic valve replacement. International Journal of Cardiology, 270, 83–88. -
Statins Reduce Thoracic Aortic Aneurysm Growth in Marfan Syndrome Mice via Inhibition of the Ras-Induced ERK (Extracellular Signal-Regulated Kinase) Signaling Pathway
Sato, T., Arakawa, M., Tashima, Y., Tsuboi, E., Burdon, G., Trojan, J., … Fischbein, M. P. (2018). Statins Reduce Thoracic Aortic Aneurysm Growth in Marfan Syndrome Mice via Inhibition of the Ras-Induced ERK (Extracellular Signal-Regulated Kinase) Signaling Pathway. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 7(21), e008543. -
Time-to-operation does not predict outcome in acute type A aortic dissection complicated by neurologic injury at presentation.
Chiu, P., Rotto, T. J., Goldstone, A. B., Whisenant, J. B., Woo, Y. J., & Fischbein, M. P. (2018). Time-to-operation does not predict outcome in acute type A aortic dissection complicated by neurologic injury at presentation. The Journal of Thoracic and Cardiovascular Surgery. -
Endovascular Versus Open Repair of Intact Descending Thoracic Aortic Aneurysms
Chiu, P., Goldstone, A. B., Schaffer, J. M., Lingala, B., Miller, D. C., Mitchell, R. S., … Dake, M. D. (2019). Endovascular Versus Open Repair of Intact Descending Thoracic Aortic Aneurysms. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 73(6), 643–51. -
Regenerative cellular therapy: How to enrich the mesenchymal stem cell content in the perfinfarction zone after myocardial infarction
Schrelpfer, S., Deuse, T., Stein, W., Reichenspurner, H., Fischbein, M. P., Robbins, R. C., & Pelletier, M. P. (2007). Regenerative cellular therapy: How to enrich the mesenchymal stem cell content in the perfinfarction zone after myocardial infarction. CIRCULATION, 116(16), 202. -
Stem cell transplantation: Organ distribution after intravenous injection.
Schrepfer, S., Deuse, T., Reichenspurner, H., Fischbein, M. P., Robbins, R. C., & Pelletier, M. P. (2007). Stem cell transplantation: Organ distribution after intravenous injection. AMERICAN JOURNAL OF TRANSPLANTATION, 7, 516–17. -
Novel role of NANOG in smooth muscle cell phenotypic modulation during aortic dissections
Shahbazi, M., & Fischbein, M. (2017). Novel role of NANOG in smooth muscle cell phenotypic modulation during aortic dissections. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 154(5), 1522–23. -
Long-term microRNA-29b Suppression Prevents Aneurysm Development in Marfan Syndrome Model Mouse
Okamura, H., Emrich, F., Dalal, A., Connolly, A., & Fischbein, M. (2013). Long-term microRNA-29b Suppression Prevents Aneurysm Development in Marfan Syndrome Model Mouse. CIRCULATION, 128(22). -
Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Occlusive Disease
Van Der Bogt, K. E., Hellingman, A. A., Lijkwan, M. A., Bos, E. J., de Vries, M. R., Fischbein, M. P., … Wu, J. C. (2009). Molecular Imaging of Bone Marrow Mononuclear Cell Survival and Homing in Murine Peripheral Artery Occlusive Disease. CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. -
Metformin as a Cardioprotective Agent in Heart Transplantation Decreases Ischemia-Reperfusion Injury and Chronic Rejection
Troke, J. J., Itoh, S., Kimura, N., Velotta, J. B., Yoshioka, H., Niizuma, K., … Fischbein, M. P. (2009). Metformin as a Cardioprotective Agent in Heart Transplantation Decreases Ischemia-Reperfusion Injury and Chronic Rejection. CIRCULATION, 120(18), S796. -
The Effects of Ischemia-Reperfusion Injury on Bcl-2
Stein, W., Bartos, J., Schrepfer, S., Hoyt, G., Robbins, R. C., & Fischbein, M. (2008). The Effects of Ischemia-Reperfusion Injury on Bcl-2. CIRCULATION, 118(18), S707. -
Prevention of Dilated Cardiomyopathy with Nitroxides
Stein, W., Bartos, J., Carre, A., Yamada, M., Schrepfer, S., Robbins, R., & Fischbein, M. (2008). Prevention of Dilated Cardiomyopathy with Nitroxides. CIRCULATION, 118(18), S497. -
Immediate operation for acute type A aortic dissection complicated by visceral or peripheral malperfusion
Chiu, P., Tsou, S., Goldstone, A. B., Louie, M., Woo, Y. J., & Fischbein, M. P. (2018). Immediate operation for acute type A aortic dissection complicated by visceral or peripheral malperfusion. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 156(1), 18-+. -
Limited root repair in acute type A aortic dissection is safe but results in increased risk of reoperation
Chiu, P., Trojan, J., Tsou, S., Goldstone, A. B., Woo, Y. J., & Fischbein, M. P. (2018). Limited root repair in acute type A aortic dissection is safe but results in increased risk of reoperation. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 155(1), 1-+. -
Current evidence for prosthesis selection: What can we really say?
Chiu, P., Goldstone, A. B., Fischbein, M. P., & Woo, Y. J. (2019). Current evidence for prosthesis selection: What can we really say? The Journal of Thoracic and Cardiovascular Surgery. -
Anatomically specific reactive oxygen species production participates in Marfan syndrome aneurysm formation.
Emrich, F., Penov, K., Arakawa, M., Dhablania, N., Burdon, G., Pedroza, A. J., … Fischbein, M. P. (2019). Anatomically specific reactive oxygen species production participates in Marfan syndrome aneurysm formation. Journal of Cellular and Molecular Medicine. -
Time-to-operation does not predict outcome in acute type A aortic dissection complicated by neurologic injury at presentation
Chiu, P., Rotto, T. J., Goldstone, A. B., Whisenant, J. B., Woo, Y. J., & Fischbein, M. P. (2019). Time-to-operation does not predict outcome in acute type A aortic dissection complicated by neurologic injury at presentation. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 158(3), 665–72. -
"Cheese Wire" Fenestration of Dissection Intimal Flap to Facilitate Thoracic Endovascular Aortic Repair in Chronic Dissection.
Iwakoshi, S., Watkins, C. A., Ogawa, Y., Fischbein, M., Lee, A., Lee, J. T., … Dake, M. D. (2019). "Cheese Wire" Fenestration of Dissection Intimal Flap to Facilitate Thoracic Endovascular Aortic Repair in Chronic Dissection. Journal of Vascular and Interventional Radiology : JVIR. -
Interfacility Transfer of Medicare Beneficiaries With Acute Type A Aortic Dissection and Regionalization of Care in the United States.
Goldstone, A. B., Chiu, P., Baiocchi, M., Lingala, B., Lee, J., Rigdon, J., … Woo, Y. J. (2019). Interfacility Transfer of Medicare Beneficiaries With Acute Type A Aortic Dissection and Regionalization of Care in the United States. Circulation, 140(15), 1239–50. -
Utility of High-Sensitivity and Conventional Troponin in Patients Undergoing Transcatheter Aortic Valve Replacement: Incremental Prognostic Value to B-type Natriuretic Peptide.
Kobayashi, Y., Kim, J. B., Moneghetti, K. J., Fischbein, M., Lee, A., Watkins, C. A., … Haddad, F. (2019). Utility of High-Sensitivity and Conventional Troponin in Patients Undergoing Transcatheter Aortic Valve Replacement: Incremental Prognostic Value to B-type Natriuretic Peptide. Scientific Reports, 9(1), 14936. -
Aortic growth and development of partial false lumen thrombosis are associated with late adverse events in type B aortic dissection.
Higashigaito, K., Sailer, A. M., van Kuijk, S. M., Willemink, M. J., Hahn, L. D., Hastie, T. J., … Fleischmann, D. (2019). Aortic growth and development of partial false lumen thrombosis are associated with late adverse events in type B aortic dissection. The Journal of Thoracic and Cardiovascular Surgery. -
Divergent effects of canonical and non-canonical TGF-beta signalling on mixed contractile-synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms.
Pedroza, A. J., Koyano, T., Trojan, J., Rubin, A., Palmon, I., Jaatinen, K., … Fischbein, M. P. (2019). Divergent effects of canonical and non-canonical TGF-beta signalling on mixed contractile-synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms. Journal of Cellular and Molecular Medicine. -
Improved midterm outcomes after endovascular repair of nontraumatic descending thoracic aortic rupture compared with open surgery.
Ogawa, Y., Watkins, A. C., Lingala, B., Nathan, I., Chiu, P., Iwakoshi, S., … Dake, M. D. (2019). Improved midterm outcomes after endovascular repair of nontraumatic descending thoracic aortic rupture compared with open surgery. The Journal of Thoracic and Cardiovascular Surgery. -
Fluid-structure interaction simulations of patient-specific aortic dissection.
Baumler, K., Vedula, V., Sailer, A. M., Seo, J., Chiu, P., Mistelbauer, G., … Fleischmann, D. (2020). Fluid-structure interaction simulations of patient-specific aortic dissection. Biomechanics and Modeling in Mechanobiology. -
Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement.
Makkar, R. R., Thourani, V. H., Mack, M. J., Kodali, S. K., Kapadia, S., Webb, J. G., … Leon, M. B. (2020). Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement. The New England Journal of Medicine, 382(9). -
Screening and Prophylactic Amiodarone Reduces Post-Operative Atrial Fibrillation in At-Risk Patients
Pong, T., Cyr, K., Niesen, J., Aparicio-Valenzuela, J., Carlton, C., Fischbein, M. P., … Lee, A. M. (2020). Screening and Prophylactic Amiodarone Reduces Post-Operative Atrial Fibrillation in At-Risk Patients. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 75(11), 1361–63. -
Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm.
Pedroza, A. J., Tashima, Y., Shad, R., Cheng, P., Wirka, R., Churovich, S., … Fischbein, M. P. (2020). Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology, ATVBAHA120314670. -
Impact of cognitive behavioral therapy on depression symptoms after transcatheter aortic valve replacement: A randomized controlled trial.
Edwards, K. S., Chow, E. K., Dao, C., Hossepian, D., Johnson, A. G., Desai, M., … Fearon, W. F. (2020). Impact of cognitive behavioral therapy on depression symptoms after transcatheter aortic valve replacement: A randomized controlled trial. International Journal of Cardiology. -
Type A Aortic Dissection-Experience Over 5 Decades: JACC Historical Breakthroughs in Perspective.
Zhu, Y., Lingala, B., Baiocchi, M., Tao, J. J., Toro Arana, V., Khoo, J. W., … Woo, Y. J. (2020). Type A Aortic Dissection-Experience Over 5 Decades: JACC Historical Breakthroughs in Perspective. Journal of the American College of Cardiology, 76(14), 1703–13. -
Introduction to the 2020 Circulation Cardiovascular Surgery-Themed Issue.
Ruel, M., Gardner, T., Fischbein, M., & de Lemos, J. (2020). Introduction to the 2020 Circulation Cardiovascular Surgery-Themed Issue. Circulation, 142(14), 1313–14. -
Androgens Accentuate TGF-beta Dependent Erk/Smad Activation During Thoracic Aortic Aneurysm Formation in Marfan Syndrome Male Mice.
Tashima, Y., He, H., Cui, J. Z., Pedroza, A. J., Nakamura, K., Yokoyama, N., … Fischbein, M. P. (2020). Androgens Accentuate TGF-beta Dependent Erk/Smad Activation During Thoracic Aortic Aneurysm Formation in Marfan Syndrome Male Mice. Journal of the American Heart Association, 9(20), e015773. -
Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells.
Iosef, C., Pedroza, A. J., Cui, J. Z., Dalal, A. R., Arakawa, M., Tashima, Y., … Fischbein, M. P. (2020). Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells. Scientific Reports, 10(1), 20392. -
Off-Pump Mini Thoracotomy Versus Sternotomy for Left Anterior Descending Myocardial Bridge Unroofing.
Wang, H., Pargaonkar, V. S., Hironaka, C. E., Bajaj, S. S., Abbot, C. J., O'Donnell, C. T., … Boyd, J. H. (2020). Off-Pump Mini Thoracotomy Versus Sternotomy for Left Anterior Descending Myocardial Bridge Unroofing. The Annals of Thoracic Surgery. -
Incremental Value of Aortomitral Continuity Calcification for Risk Assessment after Transcatheter Aortic Valve Replacement.
Willemink, M. J., Maret, E., Moneghetti, K. J., Kim, J. B., Haddad, F., Kobayashi, Y., … Fleischmann, D. (2019). Incremental Value of Aortomitral Continuity Calcification for Risk Assessment after Transcatheter Aortic Valve Replacement. Radiology. Cardiothoracic Imaging, 1(5), e190067. -
CT-based True- and False-Lumen Segmentation in Type B Aortic Dissection Using Machine Learning.
Hahn, L. D., Mistelbauer, G., Higashigaito, K., Koci, M., Willemink, M. J., Sailer, A. M., … Fleischmann, D. (2020). CT-based True- and False-Lumen Segmentation in Type B Aortic Dissection Using Machine Learning. Radiology. Cardiothoracic Imaging, 2(3), e190179. -
CTA pulmonary artery enlargement in patients with severe aortic stenosis: Prognostic impact after TAVR.
Turner, V. L., Jubran, A., Kim, J. B., Maret, E., Moneghetti, K. J., Haddad, F., … Fleischmann, D. (2021). CTA pulmonary artery enlargement in patients with severe aortic stenosis: Prognostic impact after TAVR. Journal of Cardiovascular Computed Tomography. -
Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations.
Shen, M., Quertermous, T., Fischbein, M. P., & Wu, J. C. (2021). Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells: Methods, Applications, and Considerations. Circulation Research, 128(5), 670–86. -
Evaluation of the Gore TAG Thoracic Branch Endoprosthesis in the Treatment of Proximal Descending Thoracic Aortic Aneurysms.
Dake, M. D., Fischbein, M. P., Bavaria, J. E., Desai, N. D., Oderich, G., Singh, M. J., … Patel, H. J. (2021). Evaluation of the Gore TAG Thoracic Branch Endoprosthesis in the Treatment of Proximal Descending Thoracic Aortic Aneurysms. Journal of Vascular Surgery. -
INTRAOPERATIVE INDUCIBILITY OF ATRIAL FIBRILLATION IMPROVES RISK STRATIFICATION AND REDUCES POST-OPERATIVE ATRIAL FIBRILLATION
Pong, T., Cyr, K., Carlton, C., Niesen, J., Aparicio-Valenzuela, J., Fischbein, M., … Lee, A. (2021). INTRAOPERATIVE INDUCIBILITY OF ATRIAL FIBRILLATION IMPROVES RISK STRATIFICATION AND REDUCES POST-OPERATIVE ATRIAL FIBRILLATION. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. ELSEVIER SCIENCE INC. -
2021 The American Association for Thoracic Surgery expert consensus document: Surgical treatment of acute type A aortic dissection.
Malaisrie, S. C., Szeto, W. Y., Halas, M., Girardi, L. N., Coselli, J. S., Sundt, T. M., … Moon, M. R. (2021). 2021 The American Association for Thoracic Surgery expert consensus document: Surgical treatment of acute type A aortic dissection. The Journal of Thoracic and Cardiovascular Surgery. -
Management of arch aneurysms with a single-branch thoracic endograft in zone 0
Dake, M. D., Bavaria, J. E., Singh, M. J., Oderich, G., Filinger, M., Fischbein, M. P., … Patel, H. J. (2021). Management of arch aneurysms with a single-branch thoracic endograft in zone 0. JTCVS TECHNIQUES, 7, 1–6. -
Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication
Guenthart, B. A., Sun, B., De Biasi, A., Fischbein, M. P., & Liou, D. Z. (2020). Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication. JTCVS TECHNIQUES, 4, 169–172. -
Management of arch aneurysms with a single-branch thoracic endograft in zone 0.
Dake, M. D., Bavaria, J. E., Singh, M. J., Oderich, G., Filinger, M., Fischbein, M. P., … Patel, H. J. (2021). Management of arch aneurysms with a single-branch thoracic endograft in zone 0. JTCVS Techniques, 7, 1–6. -
Bicuspid Aortic Valve and Ascending Aortic Aneurysm in a Twin Pregnancy.
Bryant, E., Tsai, S., Levin, E., Fleischman, D., Ansari, J., Fischbein, M., … Khandelwal, A. (2020). Bicuspid Aortic Valve and Ascending Aortic Aneurysm in a Twin Pregnancy. JACC. Case Reports, 2(1), 96–100. -
Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication.
Guenthart, B. A., Sun, B., De Biasi, A., Fischbein, M. P., & Liou, D. Z. (2020). Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication. JTCVS Techniques, 4, 169–172. -
Introduction to the 2021 Cardiovascular Surgery Themed Issue of Circulation.
Ruel, M., & Fischbein, M. (2021). Introduction to the 2021 Cardiovascular Surgery Themed Issue of Circulation. Circulation, 144(14), 1087. -
Relative strain is a novel predictor of aneurysmal degeneration of the thoracic aorta: An ex vivo mechanical study.
Chiu, P., Lee, H.-P., Dalal, A. R., Koyano, T., Nguyen, M., Connolly, A. J., … Fischbein, M. P. (2021). Relative strain is a novel predictor of aneurysmal degeneration of the thoracic aorta: An ex vivo mechanical study. JVS-Vascular Science, 2, 235–246. -
Distance between valvular leaflet and coronary ostium predicting risk of coronary obstruction during TAVR.
Oh, J.-H., Kobayashi, Y., Kang, G., Nishi, T., Willemink, M. J., Fearon, W. F., … Kim, J. B. (1800). Distance between valvular leaflet and coronary ostium predicting risk of coronary obstruction during TAVR. International Journal of Cardiology. Heart & Vasculature, 37, 100917. -
The Society of Thoracic Surgeons/American Association for Thoracic Surgery clinical practice guidelines on the management of type B aortic dissection.
MacGillivray, T. E., Gleason, T. G., Patel, H. J., Aldea, G. S., Bavaria, J. E., Beaver, T. M., … Stulak, J. (1800). The Society of Thoracic Surgeons/American Association for Thoracic Surgery clinical practice guidelines on the management of type B aortic dissection. The Journal of Thoracic and Cardiovascular Surgery. -
The Society of Thoracic Surgeons/American Association for Thoracic Surgery Clinical Practice Guidelines on the Management of Type B Aortic Dissection.
MacGillivray, T. E., Gleason, T. G., Patel, H. J., Aldea, G. S., Bavaria, J. E., Beaver, T. M., … Stulak, J. (2022). The Society of Thoracic Surgeons/American Association for Thoracic Surgery Clinical Practice Guidelines on the Management of Type B Aortic Dissection. The Annals of Thoracic Surgery. -
Acute Induced Pressure Overload Rapidly Incites Thoracic Aortic Aneurysmal Smooth Muscle Cell Phenotype.
Pedroza, A. J., Shad, R., Dalal, A. R., Yokoyama, N., Nakamura, K., Hiesinger, W., & Fischbein, M. P. (2022). Acute Induced Pressure Overload Rapidly Incites Thoracic Aortic Aneurysmal Smooth Muscle Cell Phenotype. Hypertension (Dallas, Tex. : 1979), HYPERTENSIONAHA12118640. -
Deep Learning-Based 3D Segmentation of True Lumen, False Lumen, and False Lumen Thrombosis in Type-B Aortic Dissection.
Wobben, L. D., Codari, M., Mistelbauer, G., Pepe, A., Higashigaito, K., Hahn, L. D., … Willemink, M. J. (2021). Deep Learning-Based 3D Segmentation of True Lumen, False Lumen, and False Lumen Thrombosis in Type-B Aortic Dissection. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021, 3912–3915. -
Imaging and Surveillance of Chronic Aortic Dissection: A Scientific Statement From the American Heart Association.
Fleischmann, D., Afifi, R. O., Casanegra, A. I., Elefteriades, J. A., Gleason, T. G., Hanneman, K., … Fischbein, M. P. (2022). Imaging and Surveillance of Chronic Aortic Dissection: A Scientific Statement From the American Heart Association. Circulation. Cardiovascular Imaging, 15(3), e000075. -
Tetralogy of Fallot and Aortic Dissection: Implications in Management.
Vaikunth, S. S., Chan, J. L., Woo, J. P., Bykhovsky, M. R., Lui, G. K., Ma, M., … Fischbein, M. P. (2022). Tetralogy of Fallot and Aortic Dissection: Implications in Management. JACC. Case Reports, 4(10), 581–586. -
Embryologic Origin Influences Smooth Muscle Cell Phenotypic Modulation Signatures in Murine Marfan Syndrome Aortic Aneurysm.
Pedroza, A. J., Dalal, A. R., Shad, R., Yokoyama, N., Nakamura, K., Cheng, P., … Fischbein, M. P. (2022). Embryologic Origin Influences Smooth Muscle Cell Phenotypic Modulation Signatures in Murine Marfan Syndrome Aortic Aneurysm. Arteriosclerosis, Thrombosis, and Vascular Biology, 101161ATVBAHA122317381. -
Mosaicism for the smooth muscle cell (SMC)-specific knock-in of the Acta2 R179C pathogenic variant: Implications for gene editing therapies.
Kaw, A., Pedroza, A. J., Chattopadhyay, A., Pinard, A., Guo, D., Kaw, K., … Milewicz, D. M. (2022). Mosaicism for the smooth muscle cell (SMC)-specific knock-in of the Acta2 R179C pathogenic variant: Implications for gene editing therapies. Journal of Molecular and Cellular Cardiology, 171, 102–104. -
Mid-Term Outcomes of Endovascular Repair of Aortic Arch Aneurysms with the Gore Thoracic Branch Endoprosthesis.
Liang, N. L., Dake, M. D., Fischbein, M. P., Bavaria, J. E., Desai, N. D., Oderich, G. S., … Makaroun, M. S. (2022). Mid-Term Outcomes of Endovascular Repair of Aortic Arch Aneurysms with the Gore Thoracic Branch Endoprosthesis. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery. -
Inter-observer variability of expert-derived morphologic risk predictors in aortic dissection.
Willemink, M. J., Mastrodicasa, D., Madani, M. H., Codari, M., Chepelev, L. L., Mistelbauer, G., … Fleischmann, D. (2022). Inter-observer variability of expert-derived morphologic risk predictors in aortic dissection. European Radiology. -
Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque.
Cheng, P., Wirka, R. C., Kim, J. B., Kim, H.-J. J., Nguyen, T., Kundu, R., … Quertermous, T. (2022). Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque. Nature Cardiovascular Research, 1(4), 322–333. -
Total aortic arch replacement using a frozen elephant trunk device: Results of a 1-year US multicenter trial.
Coselli, J. S., Roselli, E. E., Preventza, O., Malaisrie, S. C., Stewart, A., Stelzer, P., … LeMaire, S. A. (2022). Total aortic arch replacement using a frozen elephant trunk device: Results of a 1-year US multicenter trial. The Journal of Thoracic and Cardiovascular Surgery. -
Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling.
Shin, H. S., Thakore, A., Tada, Y., Pedroza, A. J., Ikeda, G., Chen, I. Y., … Shudo, Y. (2022). Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling. Scientific Reports, 12(1), 17605. -
Midterm Outcomes in Type A Aortic Dissection Repair with and without Malperfusion in a Hybrid Operating Room.
Dalal, A. R., Dossabhoy, S., Heng, E., Yasin, A., Leipzig, M. M., Bonham, S. A., … Watkins, A. C. (2022). Midterm Outcomes in Type A Aortic Dissection Repair with and without Malperfusion in a Hybrid Operating Room. Seminars in Thoracic and Cardiovascular Surgery. -
Registry of Aortic Diseases to Model Adverse Events and Progression (ROADMAP) in Uncomplicated Type B Aortic Dissection: Study Design and Rationale.
Mastrodicasa, D., Willemink, M. J., Turner, V. L., Hinostroza, V., Codari, M., Hanneman, K., … Fleischmann, D. (2022). Registry of Aortic Diseases to Model Adverse Events and Progression (ROADMAP) in Uncomplicated Type B Aortic Dissection: Study Design and Rationale. Radiology. Cardiothoracic Imaging, 4(6), e220039. -
Outcomes of Reoperative Aortic Root Replacement After Previous Acute Type A Dissection Repair.
Pedroza, A. J., Dalal, A. R., Krishnan, A., Yokoyama, N., Nakamura, K., Tognozzi, E., … Fischbein, M. P. (2023). Outcomes of Reoperative Aortic Root Replacement After Previous Acute Type A Dissection Repair. Seminars in Thoracic and Cardiovascular Surgery. -
Outcomes after concomitant arch replacement at the time of aortic root surgery.
Krishnan, A., Dalal, A. R., Pedroza, A. J., Nakamura, K., Yokoyama, N., Tognozzi, E., … MacArthur, J. W. (2023). Outcomes after concomitant arch replacement at the time of aortic root surgery. JTCVS Open, 13, 1–8. -
Blood transfusion in aortic root surgery impairs midterm survival.
Dalal, A. R., Pedroza, A. J., Krishnan, A., Min, Y., Tognozzi, E., Yokoyama, N., … Fischbein, M. P. (2023). Blood transfusion in aortic root surgery impairs midterm survival. JTCVS Open, 13, 9–19. -
Lineage-Specific Induced Pluripotent Stem Cell-Derived Smooth Muscle Cell Modeling Predicts Integrin Alpha-V Antagonism Reduces Aortic Root Aneurysm Formation in Marfan Syndrome Mice.
Nakamura, K., Dalal, A. R., Yokoyama, N., Pedroza, A. J., Kusadokoro, S., Mitchel, O., … Fischbein, M. P. (2023). Lineage-Specific Induced Pluripotent Stem Cell-Derived Smooth Muscle Cell Modeling Predicts Integrin Alpha-V Antagonism Reduces Aortic Root Aneurysm Formation in Marfan Syndrome Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. -
Smooth Muscle Cell Klf4 Expression Is Not Required for Phenotype Modulation or Aneurysm Formation in Marfan Syndrome Mice.
Pedroza, A. J., Dalal, A. R., Shad, R., Yokoyama, N., Nakamura, K., Mitchel, O., … Fischbein, M. P. (2023). Smooth Muscle Cell Klf4 Expression Is Not Required for Phenotype Modulation or Aneurysm Formation in Marfan Syndrome Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. -
Reduced Pulmonary Artery Distensibility Predicts Persistent Pulmonary Hypertension and 2-Year Mortality in Patients with Severe Aortic Stenosis Undergoing TAVR.
Turner, V., Maret, E., Kim, J. B., Codari, M., Hinostroza, V., Mastrodicasa, D., … Fleischmann, D. (2023). Reduced Pulmonary Artery Distensibility Predicts Persistent Pulmonary Hypertension and 2-Year Mortality in Patients with Severe Aortic Stenosis Undergoing TAVR. Academic Radiology. -
Early clinical outcomes and molecular smooth muscle cell phenotyping using a prophylactic aortic arch replacement strategy in Loeys-Dietz syndrome.
Pedroza, A. J., Cheng, P., Dalal, A. R., Baeumler, K., Kino, A., Tognozzi, E., … Fischbein, M. P. (2023). Early clinical outcomes and molecular smooth muscle cell phenotyping using a prophylactic aortic arch replacement strategy in Loeys-Dietz syndrome. The Journal of Thoracic and Cardiovascular Surgery. -
Blood transfusion in cardiac surgeries - Toward a personalized protocol.
Min, Y., Dalal, A. R., Pedroza, A. J., Pham, T. D., Panigrahi, A. K., Goldstone, A. B., … Fischbein, M. P. (2023). Blood transfusion in cardiac surgeries - Toward a personalized protocol. American Journal of Surgery. -
Nuclear Smooth Muscle a-actin in Vascular Smooth Muscle Cell Differentiation.
Kwartler, C. S., Pedroza, A. J., Kaw, A., Guan, P., Ma, S., Duan, X.-Y. Y., … Milewicz, D. M. (2023). Nuclear Smooth Muscle a-actin in Vascular Smooth Muscle Cell Differentiation. Research Square. -
Introduction to the 2023 Cardiovascular Surgery Issue.
Ruel, M., Fischbein, M. P., & de Lemos, J. A. (2023). Introduction to the 2023 Cardiovascular Surgery Issue. Circulation, 148(17), 1287–1288. -
Augmenting Mitochondrial Respiration in Immature Smooth Muscle Cells with anACTA2Pathogenic Variant Mitigates Moyamoya-like Cerebrovascular Disease.
Kaw, A., Wu, T., Starosolski, Z., Zhou, Z., Pedroza, A. J., Majumder, S., … Milewicz, D. M. (2023). Augmenting Mitochondrial Respiration in Immature Smooth Muscle Cells with anACTA2Pathogenic Variant Mitigates Moyamoya-like Cerebrovascular Disease. Research Square. -
Comprehensive Integration of Multiple Single-Cell Transcriptomic Datasets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine Atherosclerosis.
Sharma, D., DeForest Worssam, M., Pedroza, A. J., Dalal, A. R., Alemany, H., Kim, H.-J. J., … Quertermous, T. (2023). Comprehensive Integration of Multiple Single-Cell Transcriptomic Datasets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. -
Nuclear smooth muscle a-actin participates in vascular smooth muscle cell differentiation
Kwartler, C. S., Pedroza, A. J., Kaw, A., Guan, P., Ma, S., Duan, X.-yan, … Milewicz, D. M. (2023). Nuclear smooth muscle a-actin participates in vascular smooth muscle cell differentiation. NATURE CARDIOVASCULAR RESEARCH, 2(10), 937-+. -
Initial Outcomes of the Gore TAG Thoracic Branch Endoprosthesis for Endovascular Repair of Blunt Thoracic Aortic Injury.
Chou, E. L., Lu, E., Dake, M. D., Fischbein, M. P., Bavaria, J. E., Oderich, G., … Azizzadeh, A. (2024). Initial Outcomes of the Gore TAG Thoracic Branch Endoprosthesis for Endovascular Repair of Blunt Thoracic Aortic Injury. Annals of Vascular Surgery.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Aortic Bioprosthetic Valve »
- PERIGON Pivotal Trial »
- Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (Zone 0/1) »
- To Evaluate the Safety and Efficacy for GORE TAG Thoracic Endoprosthesis in the Treatment of Thoracic Aortic Disease »
Practice Locations
Center for Marfan Syndrome and Related Aortic Disorders Stanford, CA
Stanford, CACenter for Marfan Syndrome and Related Aortic Disorders
300 Pasteur Drive, 3rd Floor, Clinic A31
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Aortic Disease Center Stanford, CA
Stanford, CAAortic Disease Center
300 Pasteur Drive, 3rd Floor, Clinic A31
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Heart Surgery Clinic at Boswell Building Stanford, CA
Stanford, CAHeart Surgery Clinic at Boswell Building
300 Pasteur Drive, 3rd Floor, Clinic A31
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Valvular Heart Disease Clinic Stanford, CA
Stanford, CAValvular Heart Disease Clinic
300 Pasteur Drive, 3rd Floor, Clinic A31
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Center for Inherited Cardiovascular Disease at Stanford Stanford, CA
Stanford, CACenter for Inherited Cardiovascular Disease at Stanford
300 Pasteur Drive, Heart Clinic 1, Clinic A21
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Important Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
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Referring Physicians
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