Publications

• Inhaled anesthetics and immobility: Mechanisms, mysteries, and minimum alveolar anesthetic concentration
  Sonner, J. M., Antognini, J. F., Dutton, R. C., Flood, P., Gray, A. T., Harris, R. A., … Eger, E. I. (2003). Inhaled anesthetics and immobility: Mechanisms, mysteries, and minimum alveolar anesthetic concentration. ANESTHESIA AND ANALGESIA, 97(3), 718–40.
• Additivity versus synergy: A theoretical analysis of implications for anesthetic mechanisms
  Shafer, S. L., Hendrickx, J. F. A., Flood, P., Sonner, J., & Eger, E. I. (2008). Additivity versus synergy: A theoretical analysis of implications for anesthetic mechanisms. ANESTHESIA AND ANALGESIA, 107(2), 507–24.
• Inhaled anesthetics do not combine to produce synergistic effects regarding minimum alveolar anesthetic concentration in rats
  Eger, E. J., Tang, M., Liao, M., Laster, M. J., Solt, K., Flood, P., … Sonner, J. M. (2008). Inhaled anesthetics do not combine to produce synergistic effects regarding minimum alveolar anesthetic concentration in rats. ANESTHESIA AND ANALGESIA, 107(2), 479–85.
• Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics Eger, E. I., Zhang, Y., Laster, M., Flood, P., Kendig, J. J., & Sonner, J. M. (2002). Acetylcholine receptors do not mediate the immobilization produced by inhaled anesthetics. ANESTHESIA AND ANALGESIA, 94(6), 1500–1504.
  
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• Polymorphism in the ADRB2 Gene Explains a Small Portion of Intersubject Variability in Pain Relative to Cervical Dilation in the First Stage of Labor Terkawi, A. S., Jackson, W. M., Hansoti, S., Tabassum, R., & Flood, P. (2014). Polymorphism in the ADRB2 Gene Explains a Small Portion of Intersubject Variability in Pain Relative to Cervical Dilation in the First Stage of Labor. ANESTHESIOLOGY, 121(1), 140–48.
  
• Polymorphism in the ADRB2 gene explains a small portion of intersubject variability in pain relative to cervical dilation in the first stage of labor. Terkawi, A. S., Jackson, W. M., Hansoti, S., Tabassum, R., & Flood, P. (2014). Polymorphism in the ADRB2 gene explains a small portion of intersubject variability in pain relative to cervical dilation in the first stage of labor. Anesthesiology, 121(1), 140–48.
  
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• Mathematical Modeling of the Pain and Progress of the First Stage of Nulliparous Labor Debiec, J., Conell-Price, J., Evansmith, J., Shafer, S. L., & Flood, P. (2009). Mathematical Modeling of the Pain and Progress of the First Stage of Nulliparous Labor. ANESTHESIOLOGY, 111(5), 1093–1110.
  
• Intact Survival After Obstetric Hemorrhage and 55 Minutes of Cardiopulmonary Resuscitation. Anast, N., Kwok, J., Carvalho, B., Lipman, S., & Flood, P. (2015). Intact Survival After Obstetric Hemorrhage and 55 Minutes of Cardiopulmonary Resuscitation. A & A Case Reports, 5(1), 9–12.
  
• Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept Rodriguez, C. I., Kegeles, L. S., Levinson, A., Feng, T., Marcus, S. M., Vermes, D., … Simpson, H. B. (2013). Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept. NEUROPSYCHOPHARMACOLOGY, 38(12), 2475–83.
  
• Rapid Resolution of Obsessions After an Infusion of Intravenous Ketamine in a Patient With Treatment-Resistant Obsessive-Compulsive Disorder Rodriguez, C. I., Kegeles, L. S., Flood, P., & Simpson, H. B. (2011). Rapid Resolution of Obsessions After an Infusion of Intravenous Ketamine in a Patient With Treatment-Resistant Obsessive-Compulsive Disorder. JOURNAL OF CLINICAL PSYCHIATRY, 72(4), 567–569.
  
• In vivo effects of ketamine on glutamate-glutamine and gamma-aminobutyric acid in obsessive-compulsive disorder: Proof of concept Rodriguez, C. I., Kegeles, L. S., Levinson, A., Ogden, R. T., Mao, X., Milak, M. S., … Simpson, H. B. (2015). In vivo effects of ketamine on glutamate-glutamine and gamma-aminobutyric acid in obsessive-compulsive disorder: Proof of concept. PSYCHIATRY RESEARCH-NEUROIMAGING, 233(2), 141–47.
  
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• Pharmacokinetics and Pharmacodynamics of Drugs Commonly Used in Pregnancy and Parturition. Ansari, J., Carvalho, B., Shafer, S. L., & Flood, P. (2016). Pharmacokinetics and Pharmacodynamics of Drugs Commonly Used in Pregnancy and Parturition. Anesthesia and Analgesia, 122(3), 786–804.
  
• Does Ondansetron Modify Sympathectomy Due to Subarachnoid Anesthesia? Meta-analysis, Meta-regression, and Trial Sequential Analysis Terkawi, A. S., Mavridis, D., Flood, P., Wetterslev, J., Terkawi, R. S., Bin Abdulhak, A. A., … Tiouririne, M. (2016). Does Ondansetron Modify Sympathectomy Due to Subarachnoid Anesthesia? Meta-analysis, Meta-regression, and Trial Sequential Analysis. ANESTHESIOLOGY, 124(4), 846–69.
  
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• Molecular Interaction between Stress and Pain. Flood, P., & Clark, J. D. (2016). Molecular Interaction between Stress and Pain. Anesthesiology, 124(5), 994–95.
  
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• Electrical Synapses High-speed Communication in the Maintenance of Neuropathic Pain Tawfik, V. L., & Flood, P. (2016). Electrical Synapses High-speed Communication in the Maintenance of Neuropathic Pain. ANESTHESIOLOGY, 124(1), 13–15.
  
• Editorial commentary: "progressive encephalomyelitis with rigidity and myoclonus: anesthesia and glycine receptor antibodies". Flood, P. (2014). Editorial commentary: "progressive encephalomyelitis with rigidity and myoclonus: anesthesia and glycine receptor antibodies". A & A Case Reports, 2(7), 86–87.
  
• Genetic Variability in the Activity of Monoamines: A Window into the Complexity of Pain Flood, P., & Clark, D. (2014). Genetic Variability in the Activity of Monoamines: A Window into the Complexity of Pain. ANESTHESIA AND ANALGESIA, 119(5), 1032–38.
  
• Maternal inflammatory markers and term labor performance Cierny, J. T., Unal, E. R., Flood, P., Rhee, K. Y., Praktish, A., Olson, T. H., & Goetzl, L. (2014). Maternal inflammatory markers and term labor performance. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 210(5).
  
• Magnesium Is There a Signal in the Noise? Naidu, R., & Flood, P. (2013). Magnesium Is There a Signal in the Noise? ANESTHESIOLOGY, 119(1), 13–15.
  
• Oral choline supplementation for postoperative pain Sidhu, N., Davies, S., Nadarajah, A., Rivera, J., Whittington, R., Mercier, R. J., … Flood, P. (2013). Oral choline supplementation for postoperative pain. BRITISH JOURNAL OF ANAESTHESIA, 111(2), 249–255.
  
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• Role of Capsaicin in a Murine Model of Labor and Delivery Mirza, F. G., Fakhoury, A. A., Rowley, T. J., & Flood, P. D. (2013). Role of Capsaicin in a Murine Model of Labor and Delivery. ANESTHESIOLOGY, 118(2), 430–435.
  
• Chronic Pain Secondary to Childbirth Does It Exist? Flood, P., & Wong, C. A. (2013). Chronic Pain Secondary to Childbirth Does It Exist? ANESTHESIOLOGY, 118(1), 16–18.
  
• Oxytocin and catechol-O-methyltransferase receptor genotype predict the length of the first stage of labor Terkawi, A. S., Jackson, W. M., Thiet, M.-P., Hansoti, S., Tabassum, R., & Flood, P. (2012). Oxytocin and catechol-O-methyltransferase receptor genotype predict the length of the first stage of labor. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 207(3).
  
• Imaging Intracranial Pressure An Introduction to Ultrasonography of the Optic Nerve Sheath Rollins, M., & Flood, P. (2012). Imaging Intracranial Pressure An Introduction to Ultrasonography of the Optic Nerve Sheath. ANESTHESIOLOGY, 116(5), 983–984.
  
• Cesarean Hysterectomy Requiring Emergent Thoracotomy A Case Report of a Complication of Placenta Percreta Requiring a Multidisciplinary Effort Pri-Paz, S., Devine, P. C., Miller, R. S., Flood, P. D., Laifer-Narin, S. L., & Wright, J. D. (2012). Cesarean Hysterectomy Requiring Emergent Thoracotomy A Case Report of a Complication of Placenta Percreta Requiring a Multidisciplinary Effort. JOURNAL OF REPRODUCTIVE MEDICINE, 57(1-2), 58–60.
  
• Anaesthetic considerations for non-obstetric surgery during pregnancy. Reitman, E., & Flood, P. (2011). Anaesthetic considerations for non-obstetric surgery during pregnancy. British Journal of Anaesthesia, 107, i72–8.
  
• A Terrible Headache in Obstetric Anesthesia Flood, P., & Li, G. (2012). A Terrible Headache in Obstetric Anesthesia. ANESTHESIOLOGY, 116(2), 242–243.
  
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• Fetal Anesthesia and Brain Development Flood, P. (2011). Fetal Anesthesia and Brain Development. ANESTHESIOLOGY, 114(3), 479–480.
  
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• PRO: Accumulating Evidence for an Outrageous Claim Flood, P. (2010). PRO: Accumulating Evidence for an Outrageous Claim. ANESTHESIA AND ANALGESIA, 111(1), 86–87.
  
• Antinociceptive and anti-inflammatory effects of choline in a mouse model of postoperative pain Rowley, T. J., McKinstry, A., GREENIDGE, E., Smith, W., & Flood, P. (2010). Antinociceptive and anti-inflammatory effects of choline in a mouse model of postoperative pain. BRITISH JOURNAL OF ANAESTHESIA, 105(2), 201–207.
  
• Wasabi and a Volatile Anesthetic Gallos, G., & Flood, P. (2010). Wasabi and a Volatile Anesthetic. ANESTHESIOLOGY, 112(6), 1309–1310.
  
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• Primary versus Secondary Outcomes in Gargantuan Studies Flood, P. (2009). Primary versus Secondary Outcomes in Gargantuan Studies. ANESTHESIOLOGY, 111(4), 704–705.
  
• The Stressed-out Rat A Model for Anesthetic Prevention of Post-Traumatic Stress Disorder Flood, P. D. (2009). The Stressed-out Rat A Model for Anesthetic Prevention of Post-Traumatic Stress Disorder. ANESTHESIOLOGY, 110(3), 447–448.
  
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• A PILOT-STUDY OF RISK-FACTORS FOR DEMENTIA IN PARKINSONS-DISEASE Marder, K., Flood, P., Cote, L., & Mayeux, R. (1990). A PILOT-STUDY OF RISK-FACTORS FOR DEMENTIA IN PARKINSONS-DISEASE. MOVEMENT DISORDERS, 5(2), 156–161.
  
• alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected Flood, P., RamirezLatorre, J., & Role, L. (1997). alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected. ANESTHESIOLOGY, 86(4), 859–865.
  
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• Advances in neurobiology of the neuromuscular junction - Implications for the anesthesiologist Naguib, M., Flood, P., McArdle, J. J., & Brenner, H. R. (2002). Advances in neurobiology of the neuromuscular junction - Implications for the anesthesiologist. ANESTHESIOLOGY, 96(1), 202–231.
  
• Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha 7 and alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes Coates, K. M., & Flood, P. (2001). Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha 7 and alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes. BRITISH JOURNAL OF PHARMACOLOGY, 134(4), 871–879.
  
• Thiopental is a competitive inhibitor at the human alpha 7 nicotinic acetylcholine receptor Coates, K. M., Mather, L. E., Johnson, R., & Flood, P. (2001). Thiopental is a competitive inhibitor at the human alpha 7 nicotinic acetylcholine receptor. ANESTHESIA AND ANALGESIA, 92(4), 930–933.
  
• General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility Krasowski, M. D., Jenkins, A., Flood, P., Kung, A. Y., HOPFINGER, A. J., & Harrison, N. L. (2001). General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 297(1), 338–351.
  
• Intravenous anesthetics differentially modulate ligand-gated ion channels Flood, P., & Krasowski, M. D. (2000). Intravenous anesthetics differentially modulate ligand-gated ion channels. ANESTHESIOLOGY, 92(5), 1418–1425.
  
• Droperidol suppresses spontaneous electrical activity in neurons cultured from ventral midbrain - Implications for neuroleptanesthesia Heyer, E. J., & Flood, P. (2000). Droperidol suppresses spontaneous electrical activity in neurons cultured from ventral midbrain - Implications for neuroleptanesthesia. BRAIN RESEARCH, 863(1-2), 20–24.
  
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• Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: In vitro and in vivo selectivity Damaj, M. I., Flood, P., Ho, K. K., May, E. L., & Martin, B. R. (2005). Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: In vitro and in vivo selectivity. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 312(2), 780–785.
  
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• Volatile anesthetics reduce agonist affinity at nicotinic acetylcholine receptors in the brain Rada, E. M., Tharakan, E. C., & Flood, P. (2003). Volatile anesthetics reduce agonist affinity at nicotinic acetylcholine receptors in the brain. ANESTHESIA AND ANALGESIA, 96(1), 108–111.
  
• Acetylcholine receptors and thresholds for convulsions from flurothyl and 1,2-dichlorohexafluorocyclobutane Eger, E. I., Gong, D., Xing, Y. L., Raines, D. E., & Flood, P. (2002). Acetylcholine receptors and thresholds for convulsions from flurothyl and 1,2-dichlorohexafluorocyclobutane. ANESTHESIA AND ANALGESIA, 95(6), 1611–1615.
  
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• Sensitivity of the alpha 7 nicotinic acetylcholine receptor to isoflurane may depend on receptor inactivation Flood, P., & Coates, K. M. (2002). Sensitivity of the alpha 7 nicotinic acetylcholine receptor to isoflurane may depend on receptor inactivation. ANESTHESIA AND ANALGESIA, 95(1), 83–87.
  
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• Galloping in full pursuit of the mechanism of anesthetic immobility Hemmings, H. C., & Flood, P. (2008). Galloping in full pursuit of the mechanism of anesthetic immobility. ANESTHESIOLOGY, 108(6), 975–976.
  
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• A new treatment for hypoxic brain injury? Flood, P. (2007). A new treatment for hypoxic brain injury? ANESTHESIA AND ANALGESIA, 105(3), 559–560.
  
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• Strategies for effective postoperative pain management Diaz, G., & Flood, P. (2006). Strategies for effective postoperative pain management. MINERVA ANESTESIOLOGICA, 72(3), 145–150.
  
• Behavioral results of isoflurane inhibition of neuronal nicotinic acetylcholine receptors Flood, P., & Sonner, J. M. (2002). Behavioral results of isoflurane inhibition of neuronal nicotinic acetylcholine receptors. Presented at the 6th International Conference on Molecular and Basic Mechanisms of Anesthesia, BONN,GERMANY: PABST SCIENCE PUBLISHERS.
  
• Neuronal nicotinic acetylcholine receptor modulation by general anesthetics Flood, P., & Role, L. W. (1998). Neuronal nicotinic acetylcholine receptor modulation by general anesthetics. Presented at the 5th International Conference on Molecular and Cellular Mechanisms of Anaesthesia, CALGARY,CANADA: ELSEVIER IRELAND LTD.
  
• Anaesthetic considerations for non-obstetric surgery during pregnancy Reitman, E., & Flood, P. (2011). Anaesthetic considerations for non-obstetric surgery during pregnancy. BRITISH JOURNAL OF ANAESTHESIA, 107, 72–78.
  
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• Neuronal nicotinic acetylcholine receptor modulation by general anesthetics. Flood, P., & Role, L. W. (1998). Neuronal nicotinic acetylcholine receptor modulation by general anesthetics. Toxicology Letters, 100-101, 149–153.
  
• Inhibition Mediated by Glycinergic and GABAergic Receptors on Excitatory Neurons in Mouse Superficial Dorsal Horn Is Location-Specific but Modified by Inflammation. Takazawa, T., Choudhury, P., Tong, C.-K., Conway, C. M., Scherrer, G., Flood, P. D., … MacDermott, A. B. (2017). Inhibition Mediated by Glycinergic and GABAergic Receptors on Excitatory Neurons in Mouse Superficial Dorsal Horn Is Location-Specific but Modified by Inflammation. Journal of Neuroscience , 37(9), 2336–48.
  
• (527) An internet-based perioperative pain psychology treatment program: results of a randomized controlled trial in breast oncology surgery patients. Darnall, B., Wheeler, A., Taub, C., MACKEY, I., Wapnir, I., Schultz, C., … Flood, P. (2016). (527) An internet-based perioperative pain psychology treatment program: results of a randomized controlled trial in breast oncology surgery patients. Journal of Pain , 17(4S), S106-?
  
• Patient choice compared with no choice of intrathecal morphine dose for caesarean analgesia: a randomized clinical trial. Carvalho, B., Mirza, F., & Flood, P. (2017). Patient choice compared with no choice of intrathecal morphine dose for caesarean analgesia: a randomized clinical trial. British Journal of Anaesthesia, 118(5), 762–71.
  
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• Patient-Centered Prescription Opioid Tapering in Community Outpatients with Chronic Pain Darnall, B., Ziadni, M., Stieg, R., Mackey, I., Kao, M.-C., & Flood, P. (2018). Patient-Centered Prescription Opioid Tapering in Community Outpatients with Chronic Pain. JAMA Internal Medicine, Feb 19.
  
• Recovery after Nulliparous Birth A Detailed Analysis of Pain Analgesia and Recovery of Function Komatsu, R., Carvalho, B., & Flood, P. D. (2017). Recovery after Nulliparous Birth A Detailed Analysis of Pain Analgesia and Recovery of Function. ANESTHESIOLOGY, 127(4), 684–94.
  
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• EFFICACY OF PATIENT CHOICE OF DIFFERENT POSTOPERATIVE ANALGESIC PROTOCOLS AFTER CESAREAN DELIVERY: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL Kowalczyk, J. J., Sutton, C. D., Flood, P., & Carvalho, B. (2018). EFFICACY OF PATIENT CHOICE OF DIFFERENT POSTOPERATIVE ANALGESIC PROTOCOLS AFTER CESAREAN DELIVERY: A RANDOMIZED PROSPECTIVE CLINICAL TRIAL. ANESTHESIA AND ANALGESIA, 126(4), 412.
  
• Impact of patient choice for different postcesarean delivery analgesic protocols on opioid consumption: a randomized prospective clinical trial. Carvalho, B., Sutton, C. D., Kowalczyk, J. J., & Flood, P. D. (2019). Impact of patient choice for different postcesarean delivery analgesic protocols on opioid consumption: a randomized prospective clinical trial. Regional Anesthesia and Pain Medicine.
  
• Patient-Centered Prescription Opioid Tapering in Community Outpatients With Chronic Pain. Darnall, B. D., Ziadni, M. S., Stieg, R. L., Mackey, I. G., Kao, M.-C. C., & Flood, P. (2018). Patient-Centered Prescription Opioid Tapering in Community Outpatients With Chronic Pain. JAMA Internal Medicine, 178(5), 707–8.
  
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• "My Surgical Success": Effect of a Digital Behavioral Pain Medicine Intervention on Time to Opioid Cessation After Breast Cancer Surgery-A Pilot Randomized Controlled Clinical Trial. Darnall, B. D., Ziadni, M. S., Krishnamurthy, P., Flood, P., Heathcote, L., Mackey, I. G., … Wheeler, A. (2019). "My Surgical Success": Effect of a Digital Behavioral Pain Medicine Intervention on Time to Opioid Cessation After Breast Cancer Surgery-A Pilot Randomized Controlled Clinical Trial. Pain Medicine (Malden, Mass.).
  
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• Comparative Effectiveness of Cognitive Behavioral Therapy for Chronic Pain and Chronic Pain Self-Management within the Context of Voluntary Patient-Centered Prescription Opioid Tapering: The EMPOWER Study Protocol. Darnall, B. D., Mackey, S. C., Lorig, K., Kao, M.-C. C., Mardian, A., Stieg, R., … Cheung, M. (2019). Comparative Effectiveness of Cognitive Behavioral Therapy for Chronic Pain and Chronic Pain Self-Management within the Context of Voluntary Patient-Centered Prescription Opioid Tapering: The EMPOWER Study Protocol. Pain Medicine (Malden, Mass.).
  
• "My Surgical Success": Effect of a Digital Behavioral Pain Medicine Intervention on Time to Opioid Cessation After Breast Cancer Surgery-A Pilot Randomized Controlled Clinical Trial Darnall, B. D., Ziadni, M. S., Krishnamurthy, P., Flood, P., Heathcote, L. C., Mackey, I. G., … Wheeler, A. (2019). "My Surgical Success": Effect of a Digital Behavioral Pain Medicine Intervention on Time to Opioid Cessation After Breast Cancer Surgery-A Pilot Randomized Controlled Clinical Trial. PAIN MEDICINE, 20(11), 2228–37.
  
• Factors associated with persistent pain after childbirth: a narrative review. Komatsu, R., Ando, K., & Flood, P. D. (2020). Factors associated with persistent pain after childbirth: a narrative review. British Journal of Anaesthesia.