Biography
Dr. Guenthart is a board-certified, fellowship-trained cardiothoracic surgeon. He is a clinical assistant professor in the Department of Cardiothoracic Surgery.
He specializes in providing leading-edge surgical treatment for people with cancer and end-stage heart and lung disease. He performs the full range of surgical procedures ranging from minimally invasive thoracic surgery to heart and lung transplantation. Dr. Guenthart practices all aspects of thoracic surgery, including procedures for benign and malignant conditions of the airway, lung, mediastinum, esophagus, and foregut. He has a particular interest in minimally invasive techniques and has extensive experience in video-assisted thoracoscopic surgical (VATS), laparoscopic, robotic, endoscopic, and bronchoscopic approaches.
Dr. Guenthart earned his medical degree at Temple University School of Medicine. He completed general surgery residency at Cornell and a post-doctoral research fellowship in tissue bioengineering at Columbia University in the Laboratory for Stem Cells and Tissue Engineering. He then completed cardiothoracic surgery fellowship and advanced fellowship training in cardiothoracic transplantation and mechanical circulatory support at Stanford University.
Dr. Guenthart has conducted research supported by grants from the National Institutes of Health, Stanford University School of Medicine, and Columbia University. Dr. Guenthart has a particular interest in end-stage lung disease and his research focuses on lung perfusion and bioengineering strategies to promote lung recovery and regeneration. He has published in peer-reviewed journals such as Nature Medicine, Nature Biomedical Engineering, the Journal of Heart and Lung Transplantation. He has made numerous presentations to his peers at national conferences and given invited talks on patient selection, organ allocation, and other aspects of transplantation.
Dr. Guenthart is a member of the Society of Thoracic Surgeons, Western Thoracic Surgical Association, Biomedical Engineering Society, American College of Surgeons, Association for Academic Surgery, and Alpha Omega Alpha Medical Honor Society.
He specializes in providing leading-edge surgical treatment for people with cancer and end-stage heart and lung disease. He performs the full range of surgical procedures ranging from minimally invasive thoracic surgery to heart and lung transplantation. Dr. Guenthart practices all aspects of thoracic surgery, including procedures for benign and malignant conditions of the airway, lung, mediastinum, esophagus, and foregut. He has a particular interest in minimally invasive techniques and has extensive experience in video-assisted thoracoscopic surgical (VATS), laparoscopic, robotic, endoscopic, and bronchoscopic approaches.
Dr. Guenthart earned his medical degree at Temple University School of Medicine. He completed general surgery residency at Cornell and a post-doctoral research fellowship in tissue bioengineering at Columbia University in the Laboratory for Stem Cells and Tissue Engineering. He then completed cardiothoracic surgery fellowship and advanced fellowship training in cardiothoracic transplantation and mechanical circulatory support at Stanford University.
Dr. Guenthart has conducted research supported by grants from the National Institutes of Health, Stanford University School of Medicine, and Columbia University. Dr. Guenthart has a particular interest in end-stage lung disease and his research focuses on lung perfusion and bioengineering strategies to promote lung recovery and regeneration. He has published in peer-reviewed journals such as Nature Medicine, Nature Biomedical Engineering, the Journal of Heart and Lung Transplantation. He has made numerous presentations to his peers at national conferences and given invited talks on patient selection, organ allocation, and other aspects of transplantation.
Dr. Guenthart is a member of the Society of Thoracic Surgeons, Western Thoracic Surgical Association, Biomedical Engineering Society, American College of Surgeons, Association for Academic Surgery, and Alpha Omega Alpha Medical Honor Society.
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Professional Summary
Education & Certifications
- FACS, The American College of Surgeons (2024)
- Board Certification: American Board of Thoracic Surgery, Thoracic and Cardiac Surgery (2023)
- Fellowship: Stanford University Dept of Cardiothoracic Surgery (2022) CA
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- Fellowship: Stanford University Dept of Cardiothoracic Surgery (2021) CA
- Board Certification: American Board of Surgery, General Surgery (2020)
- Residency: New York Presbyterian Cornell Campus General Surgery Residency (2019) NY
- Medical Education: Temple University School of Medicine Registrar (2012) PA
Administrative Appointments
- Attending Cardiothoracic Surgeon, Lucille Packard Children's Hospital (2022 - Present)
- Attending Cardiothoracic Surgeon, Stanford Hospital and Clinics (2022 - Present)
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Publications
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Resident education in robotic thoracic surgery
Guenthart, B. A., & Lui, N. S. (2020). Resident education in robotic thoracic surgery. VIDEO-ASSISTED THORACIC SURGERY, 5. -
Commentary: Lung cancer outcomes reporting within the VA system: room for improvement.
Guenthart, B. A., Backhus, L. M., & Lui, N. S. (2020). Commentary: Lung cancer outcomes reporting within the VA system: room for improvement. Seminars in Thoracic and Cardiovascular Surgery. -
Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs.
Hozain, A. E., O'Neill, J. D., Pinezich, M. R., Tipograf, Y., Donocoff, R., Cunningham, K. M., … Vunjak-Novakovic, G. (2020). Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs. Nature Medicine, 26(7), 1102–13. -
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Intracardiac paragangliomas: surgical approach and perioperative management.
Guenthart, B. A., Trope, W., Keeyapaj, W., Weiel, J. J., Edmonson, A., MacArthur, J. W., … Lui, N. S. (2020). Intracardiac paragangliomas: surgical approach and perioperative management. General Thoracic and Cardiovascular Surgery. -
Greater Ipsilateral Rectus Muscle Atrophy after Robotic Thoracic Surgery Compared to Open and VATS Approaches
Wang, Y., Bhandari, P., Trope, W., Guenthart, B. A., Guo, H. H., Liou, D., … Lui, N. (2020). Greater Ipsilateral Rectus Muscle Atrophy after Robotic Thoracic Surgery Compared to Open and VATS Approaches. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. ELSEVIER SCIENCE INC. -
Gut bioengineering strategies for regenerative medicine.
O'Neill, J. D., Pinezich, M. R., Guenthart, B. A., & Vunjak-Novakovic, G. (2020). Gut bioengineering strategies for regenerative medicine. American Journal of Physiology. Gastrointestinal and Liver Physiology. -
Resection of a Giant Epithelioid Hemangioendothelioma Arising from the Superior Vena Cava.
Elliott, I. A., Kasinpila, P., Guenthart, B. A., MacArthur, J. W., & Berry, M. F. (2021). Resection of a Giant Epithelioid Hemangioendothelioma Arising from the Superior Vena Cava. The Annals of Thoracic Surgery. -
First lung and kidney multi-organ transplant following COVID-19 Infection.
Guenthart, B. A., Krishnan, A., Alassar, A., Madhok, J., Kakol, M., Miller, S., … Woo, Y. J. (2021). First lung and kidney multi-organ transplant following COVID-19 Infection. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. -
Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication
Guenthart, B. A., Sun, B., De Biasi, A., Fischbein, M. P., & Liou, D. Z. (2020). Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication. JTCVS TECHNIQUES, 4, 169–172. -
Non-destructive vacuum-assisted measurement of lung elastic modulus.
Chen, J., Mir, S. M., Pinezich, M. R., O'Neill, J. D., Guenthart, B. A., Bacchetta, M., … Kim, J. (2021). Non-destructive vacuum-assisted measurement of lung elastic modulus. Acta Biomaterialia. -
Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication.
Guenthart, B. A., Sun, B., De Biasi, A., Fischbein, M. P., & Liou, D. Z. (2020). Surgical technique for atrial-esophageal fistula repair after catheter ablation: An underrecognized complication. JTCVS Techniques, 4, 169–172. -
Extended Static Hypothermic Preservation In Cardiac Transplantation: A Case Report.
Guenthart, B. A., Krishnan, A., Koyano, T., La Francessca, S., Chan, J., Alassar, A., … Woo, Y. J. (2021). Extended Static Hypothermic Preservation In Cardiac Transplantation: A Case Report. Transplantation Proceedings. -
Xenogeneic support for the recovery of human donor organs.
O'Neill, J. D., Guenthart, B. A., Hozain, A. E., & Bacchetta, M. (2021). Xenogeneic support for the recovery of human donor organs. The Journal of Thoracic and Cardiovascular Surgery. -
Homogeneous Distribution of Exogenous Cells onto De-epithelialized Rat Trachea via Instillation of Cell-Loaded Hydrogel.
Chen, J., Mir, S. M., Pinezich, M. R., O'Neill, J. D., Guenthart, B. A., Bacchetta, M., … Kim, J. (2021). Homogeneous Distribution of Exogenous Cells onto De-epithelialized Rat Trachea via Instillation of Cell-Loaded Hydrogel. ACS Biomaterials Science & Engineering. -
Cannulation Strategies in Ex Vivo Lung Perfusion.
Guenthart, B. A., O'Neill, J. D., & Bacchetta, M. (2021). Cannulation Strategies in Ex Vivo Lung Perfusion. ASAIO Journal (American Society for Artificial Internal Organs : 1992). -
Exvivo aortic valve replacement before orthotopic heart transplantation.
Elde, S. F., Guenthart, B. A., Shudo, Y., & Woo, Y. J. (2022). Exvivo aortic valve replacement before orthotopic heart transplantation. JTCVS Techniques, 12, 118–120. -
Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue.
Mir, S. M., Chen, J., Pinezich, M. R., O'Neill, J. D., Guenthart, B. A., Vunjak-Novakovic, G., & Kim, J. (2022). Imaging-Guided Bioreactor for Generating Bioengineered Airway Tissue. Journal of Visualized Experiments : JoVE, (182). -
Pathological remodeling of distal lung matrix in end-stage cystic fibrosis patients.
Pinezich, M. R., Tamargo, M. A., Fleischer, S., Reimer, J. A., Hudock, M. R., Hozain, A. E., … Vunjak-Novakovic, G. (2022). Pathological remodeling of distal lung matrix in end-stage cystic fibrosis patients. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. -
Sound-guided assessment and localization of pulmonary air leak
Pinezich, M. R., Mir, S. M., Reimer, J. A., Kaslow, S. R., Chen, J., Guenthart, B. A., … Kim, J. (2022). Sound-guided assessment and localization of pulmonary air leak. BIOENGINEERING & TRANSLATIONAL MEDICINE. -
Half of Anastomotic Leaks after Esophagectomy are Undetected on Initial Postoperative Esophagram.
Elliott, I. A., Berry, M. F., Trope, W., Lui, N. S., Guenthart, B. A., Liou, D. Z., … Shrager, J. B. (2022). Half of Anastomotic Leaks after Esophagectomy are Undetected on Initial Postoperative Esophagram. The Annals of Thoracic Surgery. -
Type A Aortic Dissection With Concurrent Aortic Valve Endocarditis, Subarachnoid Hemorrhage, and Disseminated Intravascular Coagulation.
Elde, S. F., Guenthart, B. A., de Biasi, A., Dalal, A. R., Casselman, K. G., Hiesinger, W., & Burton, E. C. (2022). Type A Aortic Dissection With Concurrent Aortic Valve Endocarditis, Subarachnoid Hemorrhage, and Disseminated Intravascular Coagulation. JACC. Case Reports, 4(14), 839–843. -
Technique for xenogeneic cross-circulation to support human donor lungs ex vivo.
Kelly Wu, W., Guenthart, B. A., O'Neill, J. D., Hozain, A. E., Tipograf, Y., Ukita, R., … Bacchetta, M. (2022). Technique for xenogeneic cross-circulation to support human donor lungs ex vivo. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. -
Resection of a synovial cell sarcoma by cardiac autotransplantation: A case report.
Mullis, D. M., Zhu, Y., Guenthart, B. A., Bonham, S. A., Trope, W. L., Berry, G. J., … MacArthur, J. W. (2022). Resection of a synovial cell sarcoma by cardiac autotransplantation: A case report. JTCVS Techniques, 16, 123–127. -
Outcomes of Heart Transplantation Using a Temperature-controlled Hypothermic Storage System.
Zhu, Y., Shudo, Y., He, H., Kim, J. Y., Elde, S., Williams, K. M., … Woo, Y. J. (2022). Outcomes of Heart Transplantation Using a Temperature-controlled Hypothermic Storage System. Transplantation. -
Sound-guided assessment and localization of pulmonary air leak.
Pinezich, M. R., Mir, S. M., Reimer, J. A., Kaslow, S. R., Chen, J., Guenthart, B. A., … Kim, J. (2023). Sound-guided assessment and localization of pulmonary air leak. Bioengineering & Translational Medicine, 8(1), e10322. -
World's first en bloc heart-lung transplantation using the paragonix lungguard donor preservation system.
Neto, D., Guenthart, B., Shudo, Y., & Currie, M. E. (2023). World's first en bloc heart-lung transplantation using the paragonix lungguard donor preservation system. Journal of Cardiothoracic Surgery, 18(1), 131. -
Tracheal stenosis and airway complications in the Coronavirus Disease-19 era.
Krishnan, A., Guenthart, B. A., Choi, A., Trope, W., Berry, G. J., Pinezich, M. R., … Lui, N. S. (2023). Tracheal stenosis and airway complications in the Coronavirus Disease-19 era. Annals of Thoracic Surgery Short Reports. -
Recovery of Extracorporeal Lungs Using Cross-Circulation with Injured Recipient Swine.
Chen, P., Van Hassel, J., Pinezich, M. R., Diane, M., Hudock, M. R., Kaslow, S. R., … Vunjak-Novakovic, G. (2023). Recovery of Extracorporeal Lungs Using Cross-Circulation with Injured Recipient Swine. The Journal of Thoracic and Cardiovascular Surgery. -
Impact of hyperthermic intrathoracic chemotherapy (HITHOC) during resection of pleural mesothelioma on patient survival
Elliott, I. A., He, H., Lui, N. S., Liou, D. Z., Guenthart, B. A., Shrager, J. B., … Backhus, L. M. (2023). Impact of hyperthermic intrathoracic chemotherapy (HITHOC) during resection of pleural mesothelioma on patient survival. JOURNAL OF THORACIC DISEASE. -
Impact of hyperthermic intrathoracic chemotherapy (HITHOC) during resection of pleural mesothelioma on patient survival.
Elliott, I. A., He, H., Lui, N. S., Liou, D. Z., Guenthart, B. A., Shrager, J. B., … Backhus, L. M. (2023). Impact of hyperthermic intrathoracic chemotherapy (HITHOC) during resection of pleural mesothelioma on patient survival. Journal of Thoracic Disease, 15(11), 6140–6150. -
Risk of developing subsequent primary lung cancer after receiving radiation for breast cancer.
Wong, L.-Y., Kapula, N., He, H., Guenthart, B. A., Vitzthum, L. K., Horst, K., … Elliott, I. A. (2023). Risk of developing subsequent primary lung cancer after receiving radiation for breast cancer. JTCVS Open, 16, 919–928. -
Comparison of failure to rescue in younger versus elderly patients following lung cancer resection.
Wang, Y., Kapula, N., Yang, C.-F. J., Manapat, P., Elliott, I. A., Guenthart, B. A., … Liou, D. Z. (2023). Comparison of failure to rescue in younger versus elderly patients following lung cancer resection. JTCVS Open, 16, 855–872. -
Beating Heart Transplants-Overview and Implications for Anesthesiologists.
Kothari, P., Kiwakyou, L. M., Guenthart, B. A., & Vanneman, M. (2023). Beating Heart Transplants-Overview and Implications for Anesthesiologists. Journal of Cardiothoracic and Vascular Anesthesia. -
Beating Heart Transplantation: How to Do It.
Krishnan, A., Guenthart, B. A., Ruengesri, C., Elde, S., Zhu, Y., MacArthur, J. W., & Woo, Y. J. (2024). Beating Heart Transplantation: How to Do It. Innovations (Philadelphia, Pa.), 15569845231220678. -
Lung-Mimetic Hydrofoam Sealant to Treat Pulmonary Air Leak.
Pinezich, M. R., Mir, M., Graney, P. L., Tavakol, D. N., Chen, J., Hudock, M., … Vunjak-Novakovic, G. (2024). Lung-Mimetic Hydrofoam Sealant to Treat Pulmonary Air Leak. Advanced Healthcare Materials, e2303026. -
Four Decades of Progress in Heart-Lung Transplantation: 271 Cases at a Single Institution.
Elde, S., Baccouche, B. M., Mullis, D. M., Leipzig, M. M., Deuse, T., Krishnan, A., … Woo, Y. J. (2024). Four Decades of Progress in Heart-Lung Transplantation: 271 Cases at a Single Institution. The Journal of Thoracic and Cardiovascular Surgery. -
Beating Heart Transplant Procedures Using Organs From Donors With Circulatory Death.
Krishnan, A., Ruaengsri, C., Guenthart, B. A., Shudo, Y., Wang, H., Ma, M. R., … Woo, Y. J. (2024). Beating Heart Transplant Procedures Using Organs From Donors With Circulatory Death. JAMA Network Open, 7(3), e241828. -
What is an Adequate Margin During Sublobar Resection of =3cm N0 Subsolid Lung Adenocarcinomas?
Kamtam, D. N., Berry, M. F., Lui, N. S., Satoyoshi, M., Elliott, I. A., Liou, D. Z., … Shrager, J. B. (2024). What is an Adequate Margin During Sublobar Resection of =3cm N0 Subsolid Lung Adenocarcinomas? The Annals of Thoracic Surgery. -
Barriers to Completing Low Dose Computed Tomography Scan for Lung Cancer Screening.
Wong, L.-Y. Y., Choudhary, S., Kapula, N., Lin, M., Elliott, I. A., Guenthart, B. A., … Lui, N. S. (2024). Barriers to Completing Low Dose Computed Tomography Scan for Lung Cancer Screening. Clinical Lung Cancer. -
A Minimally Invasive Robotic Tissue Palpation Device
Mir, M., Chen, J., Patel, A., Pinezich, M. R., Guenthart, B. A., Vunjak-Novakovic, G., & Kim, J. (2024). A Minimally Invasive Robotic Tissue Palpation Device. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 71(6), 1958–1968. -
Survival, Function, and Immune Profiling after Beating Heart Transplantation.
Krishnan, A., Elde, S., Ruaengsri, C., Guenthart, B. A., Zhu, Y., Fawad, M., … Woo, Y. J. (2024). Survival, Function, and Immune Profiling after Beating Heart Transplantation. The Journal of Thoracic and Cardiovascular Surgery. -
JAK inhibition with tofacitinib rapidly increases contractile force in human skeletal muscle.
Shrager, J. B., Randle, R., Lee, M., Ahmed, S. S., Trope, W., Lui, N., … Tang, H. (2024). JAK inhibition with tofacitinib rapidly increases contractile force in human skeletal muscle. Life Science Alliance, 7(11). -
Trends in Heart Transplant Outcomes for Patients Over the Age of 70 Years in the United States: an Analysis of the Scientific Registry of Transplant Recipients Database.
Henricksen, E. J., Wayda, B., Teuteberg, J. J., Luikart, H., Njoroge, J., Guenthart, B. A., & Khush, K. K. (2024). Trends in Heart Transplant Outcomes for Patients Over the Age of 70 Years in the United States: an Analysis of the Scientific Registry of Transplant Recipients Database. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. -
Greater ipsilateral rectus muscle atrophy after robotic thoracic surgery compared with open and video-assisted thoracoscopic surgery approaches.
Wang, Y., Randle, R. J., Bhandari, P., He, H., Trope, W. L., Guenthart, B. A., … Lui, N. S. (2024). Greater ipsilateral rectus muscle atrophy after robotic thoracic surgery compared with open and video-assisted thoracoscopic surgery approaches. JTCVS Open, 20, 202–209. -
Extracorporeal membrane oxygenation as a bridge to thoracic multiorgan transplantation.
Heng, E. E., Krishnan, A., Elde, S., Garrison, A., Fawad, M., Ruaengsri, C., … MacArthur, J. W. (2024). Extracorporeal membrane oxygenation as a bridge to thoracic multiorgan transplantation. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. -
Enhancing Cytoplasmic Expression of Exogenous mRNA Through Dynamic Mechanical Stimulation.
Chen, J., Patel, A., Mir, M., Hudock, M. R., Pinezich, M. R., Guenthart, B., … Kim, J. (2024). Enhancing Cytoplasmic Expression of Exogenous mRNA Through Dynamic Mechanical Stimulation. Advanced Healthcare Materials, e2401918. -
The Role of Primary Care Providers in Lung Cancer Screening: A Cross-Sectional Survey.
Wong, L.-Y. Y., Kapula, N., Kang, A., Phadke, A. J., Schechtman, A. D., Elliott, I. A., … Lui, N. S. (2024). The Role of Primary Care Providers in Lung Cancer Screening: A Cross-Sectional Survey. Clinical Lung Cancer.
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Intracardiac paragangliomas: surgical approach and perioperative management.
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