Biography
Stroke is the leading cause of disability in the United States, drastically disrupting the lives of stroke survivors and their caretakers. Unfortunately, because of tight therapeutic time requirements, the majority of stroke patients are not eligible for the current medicines or interventions. The George Lab's research focuses on improving stroke diagnostics as well as engineering new methods to enhance stroke recovery. Our lab's primary focus is applying novel bioengineering techniques to understand the mechanisms of neural recovery (primarily in stroke) and discovering methods to improve patient recovery. We use rodent models of stroke combined with biomaterial techniques, stem cell transplants, and microfabrication to achieve these aims and evaluate our methods with behavior testing and various imaging techniques. Our ultimate goal is to translate these findings into clinical trials to help stroke patients.
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Professional Summary
Education & Certifications
- Residency: Stanford University Dept of Neurology (2012) CA
- Internship: Stanford University Internal Medicine Residency (2009) CA
- Fellowship: Stanford University Vascular Neurology Fellowship (2013) CA
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- Board Certification: American Board of Psychiatry and Neurology, Vascular Neurology (2014)
- Board Certification: American Board of Psychiatry and Neurology, Neurology (2012)
- Medical Education: Harvard Medical School (2008) MA
- PhD, Massachussetts Institute of Technology, Electrical and Medical Engineering (2005)
- BSE, Tulane University of Louisiana (1999)
Memberships
- Chair, Science Committee, American Academy of Neurology (2023 - Present)
- Ex-Officio Director, Board of Directors, American Academy of Neurology Institute (2023 - Present)
- Science Committee, American Academy of Neurology (2013 - Present)
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Administrative Appointments
- Co-Director, Neurology Faculty Mentorship & Sponsorship Program, Department of Neurology (2023 - Present)
- Member, Neuroscience PhD Program DEIB Committee (2022 - 2024)
- Member, Neuroscience Graduate IDP Faculty Program Committee (2023 - Present)
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- Neuroscience PhD Program Representative, Committee on Graduate Admissions and Policy (2017 - Present)
Publications
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Aortic arch atheroma: a plaque of a different color or more of the same?
George, P. M., & Albers, G. W. (2014). Aortic arch atheroma: a plaque of a different color or more of the same? Stroke; a Journal of Cerebral Circulation, 45(5), 1239–40. -
Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments.
George, P. M., & Steinberg, G. K. (2015). Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments. Neuron, 87(2), 297–309. -
Novel TIA biomarkers identified by mass spectrometry-based proteomics
George, P. M., Mlynash, M., Adams, C. M., Kuo, C. J., Albers, G. W., & Olivot, J.-M. (2015). Novel TIA biomarkers identified by mass spectrometry-based proteomics. INTERNATIONAL JOURNAL OF STROKE, 10(8), 1204–11. -
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Inter-rater agreement analysis of the Precise Diagnostic Score for suspected transient ischemic attack.
Cereda, C. W., George, P. M., Inoue, M., Vora, N., Olivot, J.-M., Schwartz, N., … Albers, G. W. (2016). Inter-rater agreement analysis of the Precise Diagnostic Score for suspected transient ischemic attack. International Journal of Stroke , 11(1), 85–92. -
Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics
George, P. M., Lyckman, A. W., LaVan, D. A., Hegde, A., Leung, Y., Avasare, R., … Sur, M. (2005). Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics. BIOMATERIALS, 26(17), 3511–19. -
Three-dimensional conductive constructs for nerve regeneration.
George, P. M., Saigal, R., Lawlor, M. W., Moore, M. J., LaVan, D. A., Marini, R. P., … Kohane, D. S. (2009). Three-dimensional conductive constructs for nerve regeneration. Journal of Biomedical Materials Research. Part A, 91(2), 519–527. -
Simple, three-dimensional microfabrication of electrodeposited structures
LaVan, D. A., George, P. M., & Langer, R. (2003). Simple, three-dimensional microfabrication of electrodeposited structures. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 42(11), 1262–65. -
Electrically Controlled Drug Delivery from Biotin-Doped Conductive Polymer
George, P. M., LaVan, D., Burdick, J., Chen, C. Y., Liang, E., & Langer, R. (2006). Electrically Controlled Drug Delivery from Biotin-Doped Conductive Polymer. Advanced Materials, 18(5). -
Fabrication of Screen-Printed Carbon Electrode Arrays for Sensing Neuronal Messengers
George, P. M., Muthuswamy, J., Currie, J., Thakor, N. V., & Paranjape, M. (2001). Fabrication of Screen-Printed Carbon Electrode Arrays for Sensing Neuronal Messengers. BIOMEDICAL MICRODEVICES, 3(4), 307–313. -
Beneficial effects of a semi-intensive stroke unit are beyond the monitor.
Cereda, C. W., George, P. M., Pelloni, L. S., Gandolfi-Decristophoris, P., Mlynash, M., Biancon Montaperto, L., … Bassetti, C. L. (2015). Beneficial effects of a semi-intensive stroke unit are beyond the monitor. Cerebrovascular Diseases , 39(2), 102–109. -
Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack: a pooled analysis of individual-patient data from cohort studies
Kelly, P. J., Albers, G. W., Chatzikonstantinou, A., De Marchis, G. M., Ferrari, J., George, P., … Merwick, A. (2016). Validation and comparison of imaging-based scores for prediction of early stroke risk after transient ischaemic attack: a pooled analysis of individual-patient data from cohort studies. LANCET NEUROLOGY, 15(12), 1236–45. -
Electrical preconditioning of stem cells with a conductive polymer scaffold enhances stroke recovery.
George, P. M., Bliss, T. M., Hua, T., Lee, A., Oh, B., Levinson, A., … Steinberg, G. K. (2017). Electrical preconditioning of stem cells with a conductive polymer scaffold enhances stroke recovery. Biomaterials, 142, 31–40. -
Conductive polymer scaffolds to improve neural recovery.
Song, S., & George, P. M. (2017). Conductive polymer scaffolds to improve neural recovery. Neural Regeneration Research, 12(12), 1976–78. -
Electrically Conductive Scaffold to Modulate and Deliver Stem Cells.
Oh, B., Levinson, A., Lam, V., Song, S., & George, P. (2018). Electrically Conductive Scaffold to Modulate and Deliver Stem Cells. Journal of Visualized Experiments : JoVE, (134). -
In vivo Electrical Stimulation of Neural Stem Cells via Conductive Polymer Scaffold Improves Endogenous Repair Mechanisms of Stroke Recovery
Oh, B., Song, S., Lam, V., Levinson, A., & George, P. (2018). In vivo Electrical Stimulation of Neural Stem Cells via Conductive Polymer Scaffold Improves Endogenous Repair Mechanisms of Stroke Recovery. NEUROLOGY, 90. -
Novel TIA biomarkers identified by mass spectrometry-based proteomics.
George, P. M., Mlynash, M., Adams, C. M., Kuo, C. J., Albers, G. W., & Olivot, J.-M. M. (2015). Novel TIA biomarkers identified by mass spectrometry-based proteomics. International Journal of Stroke : Official Journal of the International Stroke Society, 10(8), 1204–11. -
Conductive polymers to modulate the post-stroke neural environment
Oh, B., & George, P. (2019). Conductive polymers to modulate the post-stroke neural environment. BRAIN RESEARCH BULLETIN, 148, 10–17. -
Electrically Conductive Scaffold to Modulate and Deliver Stem Cells
Oh, B., Levinson, A., Lam, V., Song, S., & George, P. (2018). Electrically Conductive Scaffold to Modulate and Deliver Stem Cells. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (134). -
Utilizing Single Cell Immune Profiling to Identify Serum-based Biomarkers for Transient Ischemic Attacks
Therkelsen, K., Tsai, A., Mlynash, M., Oh, B., Eyngorn, I., Gaudilliere, B., & George, P. (2019). Utilizing Single Cell Immune Profiling to Identify Serum-based Biomarkers for Transient Ischemic Attacks. NEUROLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Identification of New Therapeutic Pathways by Transcriptome Analysis of Electrically Stimulated-Neural Progenitor Cells After Stroke.
Oh, B., Swaminathan, V., Lam, V., Levinson, A., & George, P. (2019). Identification of New Therapeutic Pathways by Transcriptome Analysis of Electrically Stimulated-Neural Progenitor Cells After Stroke. STROKE, 50. -
Regulating Stem Cell Function with Electrical Stimulation
Oh, B., Song, S., Lam, V., & George, P. (2019). Regulating Stem Cell Function with Electrical Stimulation. ANNALS OF NEUROLOGY, 86, S277–S278. -
Engineered stem cell mimics to enhance stroke recovery
George, P. M., Oh, B., Dewi, R., Hua, T., Cai, L., Levinson, A., … Steinberg, G. K. (2018). Engineered stem cell mimics to enhance stroke recovery. BIOMATERIALS, 178, 63–72. -
Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds.
Song, S., Amores, D., Chen, C., McConnell, K., Oh, B., Poon, A., & George, P. M. (2019). Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds. Scientific Reports, 9(1), 19565. -
Morphing electronics enable neuromodulation in growing tissue.
Liu, Y., Li, J., Song, S., Kang, J., Tsao, Y., Chen, S., … Bao, Z. (2020). Morphing electronics enable neuromodulation in growing tissue. Nature Biotechnology. -
Single-Cell Encapsulation via Click-Chemistry Alters Production of Paracrine Factors from Neural Progenitor Cells.
Oh, B., Swaminathan, V., Malkovskiy, A., Santhanam, S., McConnell, K., & George, P. M. (2020). Single-Cell Encapsulation via Click-Chemistry Alters Production of Paracrine Factors from Neural Progenitor Cells. Advanced Science (Weinheim, Baden-Wurttemberg, Germany), 7(8), 1902573. -
Modulating the Electrical and Mechanical Microenvironment to Guide Neuronal Stem Cell Differentiation.
Oh, B., Wu, Y.-W. W., Swaminathan, V., Lam, V., Ding, J., & George, P. M. (2021). Modulating the Electrical and Mechanical Microenvironment to Guide Neuronal Stem Cell Differentiation. Advanced Science (Weinheim, Baden-Wurttemberg, Germany), 8(7), 2002112. -
Conducting polymer-based granular hydrogels for injectable 3D cell scaffolds.
Feig, V. R., Santhanam, S., McConnell, K. W., Liu, K., Azadian, M., Brunel, L. G., … Bao, Z. (2021). Conducting polymer-based granular hydrogels for injectable 3D cell scaffolds. Advanced Materials Technologies, 6(6). -
Electrical stimulation of human neural stem cells via conductive polymer nerve guides enhances peripheral nerve recovery.
Song, S., McConnell, K. W., Amores, D., Levinson, A., Vogel, H., Quarta, M., … George, P. M. (2021). Electrical stimulation of human neural stem cells via conductive polymer nerve guides enhances peripheral nerve recovery. Biomaterials, 275, 120982. -
Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits.
Suhar, R. A., Marquardt, L. M., Song, S., Buabbas, H., Doulames, V. M., Johansson, P. K., … Heilshorn, S. C. (2021). Elastin-like Proteins to Support Peripheral Nerve Regeneration in Guidance Conduits. ACS Biomaterials Science & Engineering, 7(9), 4209–4220. -
Electrical modulation of transplanted stem cells improves functional recovery in a rodent model of stroke.
Oh, B., Santhanam, S., Azadian, M., Swaminathan, V., Lee, A. G., McConnell, K. W., … George, P. M. (2022). Electrical modulation of transplanted stem cells improves functional recovery in a rodent model of stroke. Nature Communications, 13(1), 1366. -
Strategic Planning at NINDS: Translating Plans into Action and Outcomes.
Jones, L. K., & George, P. (2022). Strategic Planning at NINDS: Translating Plans into Action and Outcomes. Neurology. -
Electrically controlled drug delivery from biotin-doped conductive polypyrrole
George, P. M., LaVan, D. A., Burdick, J. A., Chen, C. Y., Liang, E., & Langer, R. (2006). Electrically controlled drug delivery from biotin-doped conductive polypyrrole. ADVANCED MATERIALS, 18(5), 577-+. -
Controlling the Stem Cell Environment Via Conducting Polymer Hydrogels to Enhance Therapeutic Potential
Santhanam, S., Feig, V. R. R., McConnell, K. W. W., Song, S., Gardner, E. E. E., Patel, J. J. J., … George, P. M. M. (2023). Controlling the Stem Cell Environment Via Conducting Polymer Hydrogels to Enhance Therapeutic Potential. ADVANCED MATERIALS TECHNOLOGIES. -
Clinical Problem Solving: A 38-year-Old Woman With Systemic Lupus Erythematosus Presenting With Headache, Nausea, and Vomiting.
Silverman, A., Dugue, R., & George, P. M. (2023). Clinical Problem Solving: A 38-year-Old Woman With Systemic Lupus Erythematosus Presenting With Headache, Nausea, and Vomiting. The Neurohospitalist, 13(4), 394–398. -
Wirelessly Powered-Electrically Conductive Polymer System for Stem Cell Enhanced Stroke Recovery.
Santhanam, S., Chen, C., Oh, B., McConnell, K. W., Azadian, M. M., Patel, J. J., … George, P. M. (2023). Wirelessly Powered-Electrically Conductive Polymer System for Stem Cell Enhanced Stroke Recovery. Advanced Electronic Materials, 9(10). -
Intravenous Tenecteplase and Carotid Artery Stenting in a Young Adult With Fibromuscular Dysplasia and Carotid Dissection.
Alfandy, F., Dugue, R., Pulli, B., & George, P. M. (2023). Intravenous Tenecteplase and Carotid Artery Stenting in a Young Adult With Fibromuscular Dysplasia and Carotid Dissection. Stroke. -
Conductive gradient hydrogels allow spatial control of adult stem cell fate.
Song, S., McConnell, K. W., Shan, D., Chen, C., Oh, B., Sun, J., … George, P. M. (2024). Conductive gradient hydrogels allow spatial control of adult stem cell fate. Journal of Materials Chemistry. B. -
Eye Toward Stroke Prevention: Central Retinal Artery Occlusion and Tandem Internal Carotid Artery Occlusion.
Cheronis, C., Silverman, A., & George, P. M. (2024). Eye Toward Stroke Prevention: Central Retinal Artery Occlusion and Tandem Internal Carotid Artery Occlusion. Stroke.
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Inter-rater agreement analysis of the Precise Diagnostic Score for suspected transient ischemic attack.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
Practice Locations
Stroke Center in Palo Alto Palo Alto, CA
Palo Alto, CA
Stroke Center in Palo Alto
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereStanford Neuroscience Health Center Palo Alto, CA
Palo Alto, CA
Stanford Neuroscience Health Center
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereCerebrovascular Program Palo Alto, CA
Palo Alto, CA
Cerebrovascular Program
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereImportant Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Patient Reviews
(65 reviews)
Kind, Thorough,thoughtful and wise.
Dr. George is excellent
Dr. George is the most down to earth and caring physician I am lucky enough to have in my life.
Dr. George is a wonderful doctor and I feel very confident in him overseeing me with my health conditions and concerns.
outstanding
Dr. Paul George is very caring and patient and kind.
Excellent service
Very likely
Best medical team and staff. After being misdiagnosed, the medical team pinpointed my issues and followed up with next steps. The staff was caring, compassionate and efficient. I’m moving my medical care to Stanford Healthcare ASAP.
He listened and responded extra well to our questions. And he knows how to smile!
Every person we encountered was welcoming and very friendly and thorough.
Dr. G.
Kind, good listener and engagemetn with the patient
Very happy with my visit.
Excellent service from the minute of checking in and checking out
Great care all around!
Providers and staff knowledgeable, engaging, and professional.
He is very good and listen toyou
Perfect visit: Dr's were patient, cordial, listened, acknowledged, advised, clarified...everything excellent!
He is excellent
Dr George was prompt, thorough oin his presentation, & clinical knowledgeable
we ae satisfied
Good Professional Communication
At Disney, where I once worked, the Pixey dust settles after a while, not at Stanford Health, however.
I don’t wish a stroke on anyone but Dr. George is the best!
Dr. George is an unbelievable clinician. Possesses all the traits one dreams of in a doctor.
Dr. George is very nice and kind person. He answered all questions we had and help all we need. A very big thank you!
Very kind with me and with whom came with me.
Dr. George was through and in lightening.
Outstanding dr., and experience.
My husband, a post severe stroke victim in Feb. 2019, met with Dr. Paul George. We drive up from the Almaden Valley in San Jose as Dr. George is such a competent, friendly, knowledgeable dr. who always takes the time to answer questions & never makes you feel rushed. He is an excellent dr. & we appreciate him.
Dr. George was amazing! He listened and never rushed me and addressed all my concerns.
Excellent care & service.
Dr. George is an outstanding dr. as he is knowledgeable, kind, compassionate & now never feel as though he's just rushing you through the appointment. We are so grateful to have him as my husband's neurologist after his strokes this year. A wonderful dr.!
Dr. George was terrific in all respects, leave us with complete confidence in him and his assessment of our health issue.
Enjoyed the visit - Informative & efficient.
Dr. George was our care provider for this visit, which was our second. He is a wonderful, caring, compassionate, knowledgeable dr. We so appreciate the time he spent with us as we never felt rushed. He has a wonderful bedside manner & answered all of my questions. We would highly recommend Dr. George.
Dr. George is patient and took his time explaining his opinion. Friendly and courteous.
dr George is absolutely sincere and kind since we first met with him. He has been NOTHING BUT KIND SINCE DAY ONE!!!!
Dr. George is compassionate & kind. He is professional thru & thru.
Dr. Paul George was outstanding. He was friendly, knowledgeable, kind & understanding. He provided great information about strokes & spent sufficient time. We didn't feel as if we were being rushed through the system. The best care care provider since my husband's stroke.
All providers & nurses have been great - If I have questions I call & talk to a nurse or utilize email and the doctors have called me personally to discuss all my answers/questions.
I would highly recommend Dr. Paul George.
Stanford #1. Dr. George "great doctor".
He is excellent!
I would like to express about my special thanks and appreciation for Dr. Paul George kind his staff for their kindness. They are so helpful and professional. God bless you all.
I drive from Fresno to see Dr. George. He is worth the time & expense of the trip. Isa is also always very helpful.
Very good.
Dr. George was outstanding one of the BEST most impressed with expertise, knowledge, time spent answering questions.
Very friendly and informative.
Dr. George is a model doctor not I only am I assured that he attends to the technical tests with his expertise, I am grateful that he is an excellent listener.
Dr. George is excellent. Lucky to be his patient.
This was the first time I met Dr. George and I was very pleased with the visit. He was knowledgeable and caring and had very good communication with me
I came with 10 questions. Dr. George gave me answers to all of them. I'm satisfied with his answers.
Excellent doctor & staff excellent care.
My experience at Stanford was very good & I have the greatest confidence in the DOCTOR & nurses.
Everyon was very professional..
Excellent experience, excellent doctor!
Dr. George is excellent!
Dr. George & his staff have been very patient and explained our options well. I've already answered many of these before in this survey.
All the drs. at Stanford have been good this dr. is very good.
Experience was very good.
Dr. George is great. Well worth the 4 hours drive to see.
Provider to extra time & explained what & why he wanted MRI's & answered our questions.
Very good since Dr. George clarified I did not have a TIA, although for 3 months prior my family dr. informed me of the TIA - What a relief to know I'm in good health.
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