Casey H. Halpern, MD
Functional neurosurgeon
Associate Professor of Neurosurgery
View Professional Summary »
For Referring Physicians:
Select a Resource
For Referring Physicians:
Select a Resource
Professional Summary »
Specializing In »
Practice Locations »
Patient Ratings »
Referring Physicians »
Biography
Casey H. Halpern, MD, is Associate Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences, and Psychiatry and Behavioral Sciences at Stanford University Medical Center. Dr. Halpern received his medical degree from the University of Pennsylvania School of Medicine. He completed his residency in Neurological Surgery and a fellowship in Stereotactic and Functional Neurosurgery at the University of Pennsylvania. He focuses on the surgical treatment of movement disorders and epilepsy and has particular interest in minimally invasive surgical approaches, as well as neurostimulation procedures.
Surgical focus:
Deep brain stimulation
Laser ablation
Movement disorder surgery
Voice tremor
Epilepsy surgery
Psychiatric disease
Chronic pain
Cancer-derived pain
Trigeminal neuralgia
Hemifacial spasm
View Full Biography »
Professional Summary
Professional Education
- Board Certification: American Board of Neurological Surgery, Neurosurgery (2018)
- Residency: Perelman School of Medicine University of Pennsylvania (2014) PA
- Fellowship: Perelman School of Medicine University of Pennsylvania (2013) PA
- Internship: Perelman School of Medicine University of Pennsylvania (2008) PA
- Medical Education: Perelman School of Medicine University of Pennsylvania (2007) PA
- Fellowship, University of Pennsylvania Health System, Stereotactic and Functional Neurosurgery (2014)
- Residency, University of Pennsylvania Health System, Neurosurgery (2014)
- Internship, University of Pennsylvania Health System, General Surgery (2008)
- M.D., University of Pennsylvania School of Medicine (2007)
- B.A., University of Pennsylvania (2003)
Publications
-
Re: Halpern CH, Milby AH, Wensheng G, et al. Clearance of the cervical spine in clinically nonevaluable trauma patients. Spine 2010; 35: 1721-8
Halpern, C. H., Stein, S. C., & Milby, A. H. (2011). Re: Halpern CH, Milby AH, Wensheng G, et al. Clearance of the cervical spine in clinically nonevaluable trauma patients. Spine 2010; 35: 1721-8. SPINE, 36(14), 1165–1166. -
Re: Halpern CH, Milby AH, Wensheng G, et al. Clearance of the cervical spine in clinically nonevaluable trauma patients. Spine 2010; 35:1721-8. RESPONSE
Halpern, C. H., Schuster, J. M., Stein, S. C., & Milby, A. H. (2011). Re: Halpern CH, Milby AH, Wensheng G, et al. Clearance of the cervical spine in clinically nonevaluable trauma patients. Spine 2010; 35:1721-8. RESPONSE. SPINE, 36(14), 1167–1168. -
Deep Brain Stimulation of the Nucleus Accumbens Attenuates Binge Eating in Mice
Halpern, C. (2012). Deep Brain Stimulation of the Nucleus Accumbens Attenuates Binge Eating in Mice. BIOLOGICAL PSYCHIATRY, 71(8), 304S–304S. -
Sex Differences in Deep Brain Stimulation Amelioration of Binge Eating
Siegel, C. M., Halpern, C. H., & Bale, T. (2012). Sex Differences in Deep Brain Stimulation Amelioration of Binge Eating. BIOLOGICAL PSYCHIATRY, 71(8), 306S–306S. -
Deep brain stimulation and obesity RESPONSE
Halpern, C. H., Wolf, J. A., Jaggi, J. L., Grady, M. S., & Baltuch, G. H. (2013). Deep brain stimulation and obesity RESPONSE. JOURNAL OF NEUROSURGERY, 118(2), 487–487. -
Longevity Analysis of Currently Available Deep Brain Stimulation Devices
Halpern, C. H., McGill, K. R., Baltuch, G. H., & Jaggi, J. L. (2011). Longevity Analysis of Currently Available Deep Brain Stimulation Devices. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 89(1), 1–5. -
Carpal tunnel syndrome secondary to an osteophyte of the trapezium
Mascitelli, J. R., Halpern, C. H., Dolinskas, C. A., Zager, E. L., & Welch, W. C. (2011). Carpal tunnel syndrome secondary to an osteophyte of the trapezium. JOURNAL OF CLINICAL NEUROSCIENCE, 18(11), 1558–1559. -
Expanding applications of deep brain stimulation: a potential therapeutic role in obesity and addiction management
Halpern, C. H., Torres, N., Hurtig, H. I., Wolf, J. A., Stephen, J., Oh, M. Y., … Baltuch, G. H. (2011). Expanding applications of deep brain stimulation: a potential therapeutic role in obesity and addiction management. ACTA NEUROCHIRURGICA, 153(12), 2293–2306. -
The Effect of Intraventricular Trajectory on Brain Shift in Deep Brain Stimulation
Kramer, D. R., Halpern, C. H., Danish, S. F., Jaggi, J. L., & Baltuch, G. H. (2012). The Effect of Intraventricular Trajectory on Brain Shift in Deep Brain Stimulation. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 90(1), 20–24. -
Deep brain stimulation compared with methadone maintenance for the treatment of heroin dependence: a threshold and cost-effectiveness analysis
Stephen, J. H., Halpern, C. H., Barrios, C. J., Balmuri, U., Pisapia, J. M., Wolf, J. A., … Stein, S. C. (2012). Deep brain stimulation compared with methadone maintenance for the treatment of heroin dependence: a threshold and cost-effectiveness analysis. ADDICTION, 107(3), 624–634. -
Use of magnetic perfusion-weighted imaging to determine epidermal growth factor receptor variant III expression in glioblastoma
Tykocinski, E. S., Grant, R. A., Kapoor, G. S., Krejza, J., Bohman, L.-E., Gocke, T. A., … O'Rourke, D. M. (2012). Use of magnetic perfusion-weighted imaging to determine epidermal growth factor receptor variant III expression in glioblastoma. NEURO-ONCOLOGY, 14(5), 613–623. -
Self-administered preoperative antiseptic wash to prevent postoperative infection after deep brain stimulation
Halpern, C. H., Mitchell, G. W., Paul, A., Kramer, D. R., McGill, K. R., Buonacuore, D., … Baltuch, G. H. (2012). Self-administered preoperative antiseptic wash to prevent postoperative infection after deep brain stimulation. AMERICAN JOURNAL OF INFECTION CONTROL, 40(5), 431–433. -
Implications for programming strategy of the location of the active contact in subthalamic nucleus deep brain stimulation
Connolly, P. J., Halpern, C. H., Baltuch, G. H., Danish, S. F., & Jaggi, J. L. (2012). Implications for programming strategy of the location of the active contact in subthalamic nucleus deep brain stimulation. JOURNAL OF CLINICAL NEUROSCIENCE, 19(7), 1029–1031. -
Durability of Roux-en-Y Gastric Bypass Surgery A Meta-Regression Study
Attiah, M. A., Halpern, C. H., Balmuri, U., Vinai, P., Mehta, S., Baltuch, G. H., … Stein, S. C. (2012). Durability of Roux-en-Y Gastric Bypass Surgery A Meta-Regression Study. ANNALS OF SURGERY, 256(2), 251–254. -
Error Reduction with Routine Checklist Use during Deep Brain Stimulation Surgery
Kramer, D. R., Halpern, C. H., Connolly, P. J., Jaggi, J. L., & Baltuch, G. H. (2012). Error Reduction with Routine Checklist Use during Deep Brain Stimulation Surgery. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 90(4), 255–259. -
Pediatric indications for deep brain stimulation
Difrancesco, M. F., Halpern, C. H., Hurtig, H. H., Baltuch, G. H., & Heuer, G. G. (2012). Pediatric indications for deep brain stimulation. CHILDS NERVOUS SYSTEM, 28(10), 1701–1714. -
Can Broad-Range 16S Ribosomal Ribonucleic Acid Gene Polymerase Chain Reactions Improve the Diagnosis of Bacterial Meningitis? A Systematic Review and Meta-analysis
Srinivasan, L., Pisapia, J. M., Shah, S. S., Halpern, C. H., & Harris, M. C. (2012). Can Broad-Range 16S Ribosomal Ribonucleic Acid Gene Polymerase Chain Reactions Improve the Diagnosis of Bacterial Meningitis? A Systematic Review and Meta-analysis. ANNALS OF EMERGENCY MEDICINE, 60(5), 609–620. -
Amelioration of Binge Eating by Nucleus Accumbens Shell Deep Brain Stimulation in Mice Involves D2 Receptor Modulation
Halpern, C. H., Tekriwal, A., Santollo, J., Keating, J. G., Wolf, J. A., Daniels, D., & Bale, T. L. (2013). Amelioration of Binge Eating by Nucleus Accumbens Shell Deep Brain Stimulation in Mice Involves D2 Receptor Modulation. JOURNAL OF NEUROSCIENCE, 33(17), 7122-? -
Ethical considerations in deep brain stimulation for psychiatric illness
Grant, R. A., Halpern, C. H., Baltuch, G. H., O'Reardon, J. P., & Caplan, A. (2014). Ethical considerations in deep brain stimulation for psychiatric illness. JOURNAL OF CLINICAL NEUROSCIENCE, 21(1), 1–5. -
A step-wise approach to deep brain stimulation in mice
Halpern, C. H., Attiah, M. A., Tekriwal, A., & Baltuch, G. H. (2014). A step-wise approach to deep brain stimulation in mice. ACTA NEUROCHIRURGICA, 156(8), 1515–1521. -
Perfusion-weighted imaging identifies MR surrogates of malignant glioma molecular subtypes
Whitmore, R., Halpern, C., Kapoor, G., Wolf, R., Woo, J., Baccon, J., … O'Rourke, D. (2007). Perfusion-weighted imaging identifies MR surrogates of malignant glioma molecular subtypes. NEURO-ONCOLOGY, 9(4), 577–578. -
Dissociable numerosity and executive components of quantifier knowledge
Troiani, V., Peelle, J. E., Halpern, C., Clark, R., & Grossman, M. (2007). Dissociable numerosity and executive components of quantifier knowledge. BRAIN AND LANGUAGE, 103(1-2), 12–13. -
Brain shift during deep brain stimulation surgery for Parkinson's disease
Halpern, C. H., Danish, S. F., Baltuch, G. H., & Jaggi, J. L. (2008). Brain shift during deep brain stimulation surgery for Parkinson's disease. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 86(1), 37–43. -
Deep brain stimulation for epilepsy
Halpern, C. H., Samadani, U., Litt, B., Jaggi, J. L., & Baltuch, G. H. (2008). Deep brain stimulation for epilepsy. NEUROTHERAPEUTICS, 5(1), 59–67. -
Vagus nerve stimulation for epilepsy and depression
Milby, A. H., Halpern, C. H., & Baltuch, G. H. (2008). Vagus nerve stimulation for epilepsy and depression. NEUROTHERAPEUTICS, 5(1), 75–85. -
Traumatic coagulopathy: The effect of brain injury
Halpern, C. H., Reilly, P. M., Turtz, A. R., & Stein, S. C. (2008). Traumatic coagulopathy: The effect of brain injury. JOURNAL OF NEUROTRAUMA, 25(8), 997–1001. -
Deep brain stimulation in the treatment of obesity
Halpern, C. H., Wolf, J. A., Bale, T. L., Stunkard, A. J., Danish, S. F., Grossman, M., … Baltuch, G. H. (2008). Deep brain stimulation in the treatment of obesity. JOURNAL OF NEUROSURGERY, 109(4), 625–634. -
Prevalence of cervical spinal injury in trauma
Milby, A. H., Halpern, C. H., Guo, W., & Stein, S. C. (2008). Prevalence of cervical spinal injury in trauma. NEUROSURGICAL FOCUS, 25(5). -
Vagus Nerve Stimulation in the Treatment of Refractory Epilepsy
Milby, A. H., Halpern, C. H., & Baltuch, G. H. (2009). Vagus Nerve Stimulation in the Treatment of Refractory Epilepsy. NEUROTHERAPEUTICS, 6(2), 228–237. -
Cognition of the following bilateral deep brain stimulation surgery subthalamic nucleus for Parkinson's disease
Halpern, C. H., Rick, J. H., Danish, S. F., Grossman, M., & Baltuch, G. H. (2009). Cognition of the following bilateral deep brain stimulation surgery subthalamic nucleus for Parkinson's disease. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 24(5), 443–451. -
SUBCUTANEOUS HEPARIN FOR PROPHYLAXIS OF VENOUS THROMBOEMBOLISM IN DEEP BRAIN STIMULATION SURGERY: EVIDENCE FROM A DECISION ANALYSIS
Bauman, J. A., Church, E., Halpern, C. H., Danish, S. F., Zaghloul, K. A., Jaggi, J. L., … Baltuch, G. H. (2009). SUBCUTANEOUS HEPARIN FOR PROPHYLAXIS OF VENOUS THROMBOEMBOLISM IN DEEP BRAIN STIMULATION SURGERY: EVIDENCE FROM A DECISION ANALYSIS. NEUROSURGERY, 65(2), 276–80. -
Deep brain stimulation in the treatment of refractory epilepsy: Update on current data and future directions
Lega, B. C., Halpern, C. H., Jaggi, J. L., & Baltuch, G. H. (2010). Deep brain stimulation in the treatment of refractory epilepsy: Update on current data and future directions. NEUROBIOLOGY OF DISEASE, 38(3), 354–360. -
Intracerebral microdialysis during deep brain stimulation surgery
Kilpatrick, M., Church, E., Danish, S., Stiefel, M., Jaggi, J., Halpern, C., … Baltuch, G. (2010). Intracerebral microdialysis during deep brain stimulation surgery. JOURNAL OF NEUROSCIENCE METHODS, 190(1), 106–11. -
Clearance of the Cervical Spine in Clinically Unevaluable Trauma Patients
Halpern, C. H., Milby, A. H., Guo, W., Schuster, J. M., Gracias, V. H., & Stein, S. C. (2010). Clearance of the Cervical Spine in Clinically Unevaluable Trauma Patients. SPINE, 35(18), 1721–1728. -
Best surgical practices: a stepwise approach to the University of Pennsylvania deep brain stimulation protocol
Kramer, D. R., Halpern, C. H., Buonacore, D. L., McGill, K. R., Hurtig, H. I., Jaggi, J. L., & Baltuch, G. H. (2010). Best surgical practices: a stepwise approach to the University of Pennsylvania deep brain stimulation protocol. NEUROSURGICAL FOCUS, 29(2). -
Deep brain stimulation compared with bariatric surgery for the treatment of morbid obesity: a decision analysis study
Pisapia, J. M., Halpern, C. H., Williams, N. N., Wadden, T. A., Baltuch, G. H., & Stein, S. C. (2010). Deep brain stimulation compared with bariatric surgery for the treatment of morbid obesity: a decision analysis study. NEUROSURGICAL FOCUS, 29(2). -
Gene-environment contributions to the development of infant vagal reactivity: The interaction of dopamine and maternal sensitivity
Propper, C., Moore, G. A., Mills-Koonce, W. R., Halpern, C. T., Hill-Soderlund, A. L., Calkins, S. D., … Cox, M. (2008). Gene-environment contributions to the development of infant vagal reactivity: The interaction of dopamine and maternal sensitivity. CHILD DEVELOPMENT, 79(5), 1377–1394. -
Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology.
Ho, A. L., Erickson-DiRenzo, E., Pendharkar, A. V., Sung, C.-K., & Halpern, C. H. (2015). Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology. Neurosurgical Focus, 38(6), E6-? -
Deep Brain Stimulation for Obesity.
Ho, A. L., Sussman, E. S., Zhang, M., Pendharkar, A. V., Azagury, D. E., Bohon, C., & Halpern, C. H. (2015). Deep Brain Stimulation for Obesity. Cureus, 7(3). -
Deep brain stimulation for obesity: rationale and approach to trial design.
Ho, A. L., Sussman, E. S., Pendharkar, A. V., Azagury, D. E., Bohon, C., & Halpern, C. H. (2015). Deep brain stimulation for obesity: rationale and approach to trial design. Neurosurgical Focus, 38(6), E8-? -
Deep Brain Stimulation for Essential Vocal Tremor: A Technical Report.
Ho, A. L., Choudhri, O., Sung, C. K., DiRenzo, E. E., & Halpern, C. H. (2015). Deep Brain Stimulation for Essential Vocal Tremor: A Technical Report. Cureus, 7(3). -
Deep brain stimulation for Alzheimer disease: a decision and cost-effectiveness analysis
Mirsaeedi-Farahani, K., Halpern, C. H., Baltuch, G. H., Wolk, D. A., & Stein, S. C. (2015). Deep brain stimulation for Alzheimer disease: a decision and cost-effectiveness analysis. JOURNAL OF NEUROLOGY, 262(5), 1191–1197. -
Deep brain stimulation for obesity: rationale and approach to trial design
Ho, A. L., Sussman, E. S., Pendharkar, A. V., Azagury, D. E., Bohon, C., & Halpern, C. H. (2015). Deep brain stimulation for obesity: rationale and approach to trial design. NEUROSURGICAL FOCUS, 38(6). -
Responsive Direct Brain Stimulation for Epilepsy.
Morrell, M. J., & Halpern, C. (2016). Responsive Direct Brain Stimulation for Epilepsy. Neurosurgery Clinics of North America, 27(1), 111–21. -
Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology
Ho, A. L., Erickson-DiRenzo, E., Pendharkar, A. V., Sung, C.-K., & Halpern, C. H. (2015). Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology. NEUROSURGICAL FOCUS, 38(6). -
Long-term quality of life after posterior cervical foraminotomy for radiculopathy
Faught, R. W., Church, E. W., Halpern, C. H., Balmuri, U., Attiah, M. A., Stein, S. C., … Simeone, F. A. (2016). Long-term quality of life after posterior cervical foraminotomy for radiculopathy. CLINICAL NEUROLOGY AND NEUROSURGERY, 142, 22–25. -
Stereotactic laser ablation of the splenium for intractable epilepsy.
Ho, A. L., Miller, K. J., Cartmell, S., Inoyama, K., Fisher, R. S., & Halpern, C. H. (2016). Stereotactic laser ablation of the splenium for intractable epilepsy. Epilepsy & Behavior Case Reports, 5, 23–26. -
Long-term quality of life after posterior cervical foraminotomy for radiculopathy.
Faught, R. W., Church, E. W., Halpern, C. H., Balmuri, U., Attiah, M. A., Stein, S. C., … Simeone, F. A. (2016). Long-term quality of life after posterior cervical foraminotomy for radiculopathy. Clinical Neurology and Neurosurgery, 142, 22–25. -
Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences
Ye, L., Allen, W. E., Thompson, K. R., Tian, Q., Hsueh, B., Ramakrishnan, C., … Deisseroth, K. (2016). Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences. CELL, 165(7), 1776–88. -
Predicting variation in subject thermal response during transcranial magnetic resonance guided focused ultrasound surgery: Comparison in seventeen subject datasets.
Vyas, U., Ghanouni, P., Halpern, C. H., Elias, J., & Pauly, K. B. (2016). Predicting variation in subject thermal response during transcranial magnetic resonance guided focused ultrasound surgery: Comparison in seventeen subject datasets. Medical Physics, 43(9), 5170-? -
A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor.
Elias, W. J., Lipsman, N., Ondo, W. G., Ghanouni, P., Kim, Y. G., Lee, W., … Chang, J. W. (2016). A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor. New England Journal of Medicine, 375(8), 730–39. -
Stereotactic Bony Trajectory Preservation for Responsive Neurostimulator Lead Placement Following Depth EEG Recording.
Miller, K., & Halpern, C. H. (2016). Stereotactic Bony Trajectory Preservation for Responsive Neurostimulator Lead Placement Following Depth EEG Recording. Cure¯Us, 8(3). -
Magnetic Resonance-Guided Laser-Induced Thermal Therapy for Recurrent Brain Metastases in the Motor Strip After Stereotactic Radiosurgery.
Iyer, A., Halpern, C. H., Grant, G. A., Deb, S., & Li, G. H. (2016). Magnetic Resonance-Guided Laser-Induced Thermal Therapy for Recurrent Brain Metastases in the Motor Strip After Stereotactic Radiosurgery. Cureus, 8(12). -
Vocal Tremor: Novel Therapeutic Target for Deep Brain Stimulation.
Ravikumar, V. K., Ho, A. L., Parker, J. J., Erickson-DiRenzo, E., & Halpern, C. H. (2016). Vocal Tremor: Novel Therapeutic Target for Deep Brain Stimulation. Brain Sciences, 6(4). -
Deep brain stimulation of the nucleus accumbens for the treatment of addiction
Mueller, U. J., Voges, J., Steiner, J., Galazky, I., Heinze, H.-J., Moeller, M., … Kuhn, J. (2013). Deep brain stimulation of the nucleus accumbens for the treatment of addiction. ADDICTION REVIEWS, 1282, 119–28. -
Dissociation of numbers and objects in corticobasal degeneration and semantic dementia
Halpern, C. H., Glosser, G., Clark, R., Gee, J., Moore, P., Dennis, K., … Grossman, M. (2004). Dissociation of numbers and objects in corticobasal degeneration and semantic dementia. NEUROLOGY, 62(7), 1163–69. -
Brief Pain Inventory-Facial minimum clinically important difference
Sandhu, S. K., Halpern, C. H., Vakhshori, V., Mirsaeedi-Farahani, K., Farrar, J. T., & Lee, J. Y. K. (2015). Brief Pain Inventory-Facial minimum clinically important difference. JOURNAL OF NEUROSURGERY, 122(1), 180–90. -
Verbal mediation of number knowledge: Evidence from semantic dementia and corticobasal degeneration
Halpern, C., Clark, R., Moore, P., Antani, S., Colcher, A., & Grossman, M. (2004). Verbal mediation of number knowledge: Evidence from semantic dementia and corticobasal degeneration. BRAIN AND COGNITION, 56(1), 107–15. -
Cervical laminoforaminotomy for radiculopathy: Symptomatic and functional outcomes in a large cohort with long-term follow-up.
Church, E. W., Halpern, C. H., Faught, R. W., Balmuri, U., Attiah, M. A., Hayden, S., … Simeone, F. A. (2014). Cervical laminoforaminotomy for radiculopathy: Symptomatic and functional outcomes in a large cohort with long-term follow-up. Surgical Neurology International, 5, S536–43. -
Calculation impairment in neurodegenerative diseases
Halpern, C., McMillan, C., Moore, P., Dennis, K., & Grossman, M. (2003). Calculation impairment in neurodegenerative diseases. JOURNAL OF THE NEUROLOGICAL SCIENCES, 208(1-2), 31–38. -
Too much to count on: Impaired very small numbers in corticobasal degeneration
Halpern, C., Clark, R., Moore, P., Cross, K., & Grossman, M. (2007). Too much to count on: Impaired very small numbers in corticobasal degeneration. BRAIN AND COGNITION, 64(2), 144–49. -
Deep brain stimulation in neurologic disorders
Halpern, C., Hurtig, H., Jaggi, J., Grossman, M., Won, M., & Baltuch, G. (2007). Deep brain stimulation in neurologic disorders. PARKINSONISM & RELATED DISORDERS, 13(1), 1–16. -
Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network
Polepalli, J. S., Wu, H., Goswami, D., Halpern, C. H., Sudhof, T. C., & Malenka, R. C. (2017). Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network. NATURE NEUROSCIENCE, 20(2), 219–29. -
Awake versus asleep deep brain stimulation for Parkinson's disease: a critical comparison and meta-analysis.
Ho, A. L., Ali, R., Connolly, I. D., Henderson, J. M., Dhall, R., Stein, S. C., & Halpern, C. H. (2017). Awake versus asleep deep brain stimulation for Parkinson's disease: a critical comparison and meta-analysis. Journal of Neurology, Neurosurgery, and Psychiatry. -
Electrical stimulation and monitoring devices of the CNS: An imaging review.
Patel, S. H., Halpern, C. H., Shepherd, T. M., & Timpone, V. M. (2017). Electrical stimulation and monitoring devices of the CNS: An imaging review. Journal of Neuroradiology. Journal De Neuroradiologie. -
A Commentary on Attitudes Towards Deep Brain Stimulation for Addiction.
Lee, K. E., Bhati, M. T., & Halpern, C. H. (2016). A Commentary on Attitudes Towards Deep Brain Stimulation for Addiction. Journal of Neurology & Neuromedicine, 1(8), 1–3. -
Cost-effectiveness of focused ultrasound, radiosurgery, and DBS for essential tremor.
Ravikumar, V. K., Parker, J. J., Hornbeck, T. S., Santini, V. E., Pauly, K. B., Wintermark, M., … Halpern, C. H. (2017). Cost-effectiveness of focused ultrasound, radiosurgery, and DBS for essential tremor. Movement Disorders . -
Deciphering deep brain stimulation for depression.
Bhati, M. T., & Halpern, C. H. (2017). Deciphering deep brain stimulation for depression. The Lancet. Psychiatry. -
Transcranial MRI-guided high-intensity focused ultrasound for treatment of essential tremor: A pilot study on the correlation between lesion size, lesion location, thermal dose, and clinical outcome.
Federau, C., Goubran, M., Rosenberg, J., Henderson, J., Halpern, C. H., Santini, V., … Ghanouni, P. (2017). Transcranial MRI-guided high-intensity focused ultrasound for treatment of essential tremor: A pilot study on the correlation between lesion size, lesion location, thermal dose, and clinical outcome. Journal of Magnetic Resonance Imaging : JMRI. -
Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man.
Wu, H., Miller, K. J., Blumenfeld, Z., Williams, N. R., Ravikumar, V. K., Lee, K. E., … Halpern, C. H. (2018). Closing the loop on impulsivity via nucleus accumbens delta-band activity in mice and man. Proceedings of the National Academy of Sciences of the United States of America, 115(1), 192–97. -
Novel application of virtual reality in patient engagement for deep brain stimulation: A pilot study.
Collins, M. K., Ding, V. Y., Ball, R. L., Dolce, D. L., Henderson, J. M., & Halpern, C. H. (2018). Novel application of virtual reality in patient engagement for deep brain stimulation: A pilot study. Brain Stimulation. -
Hair sparing does not compromise real-time magnetic resonance imaging guided stereotactic laser fiber placement for temporal lobe epilepsy.
Singh, S., Kumar, K. K., Rabon, M. J., Dolce, D., & Halpern, C. H. (2018). Hair sparing does not compromise real-time magnetic resonance imaging guided stereotactic laser fiber placement for temporal lobe epilepsy. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 52, 71–73. -
It takes time to tune
Bentzley, B. S., Pannu, J., Badran, B. W., Halpern, C. H., & Williams, N. R. (2017). It takes time to tune. ANNALS OF TRANSLATIONAL MEDICINE, 5(7), 171. -
Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy
Ho, A. L., Sussman, E. S., Pendharkar, A. V., Le, S., Mantovani, A., Keebaugh, A. C., … Halpern, C. H. (2018). Improved operative efficiency using a real-time MRI-guided stereotactic platform for laser amygdalohippocampotomy. JOURNAL OF NEUROSURGERY, 128(4), 1165–72. -
Letter: Electric Beats Open New Frontiers for Deep Brain Stimulation
Halpern, C. H., Miller, K. J., Wu, H., & Tass, P. A. (2018). Letter: Electric Beats Open New Frontiers for Deep Brain Stimulation. NEUROSURGERY, 82(1), E19–E20. -
Cognitive safety of intracranial electrodes for epilepsy.
Meador, K. J., Halpern, C. H., & Hermann, B. P. (2018). Cognitive safety of intracranial electrodes for epilepsy. Epilepsia, 59(6), 1132–37. -
Neuromodulatory Treatments for Alcohol Use Disorder: A Review.
Salib, A.-M. N., Ho, A. L., Sussman, E. S., Pendharkar, A. V., & Halpern, C. H. (2018). Neuromodulatory Treatments for Alcohol Use Disorder: A Review. Brain Sciences, 8(6). -
Laser interstitial thermal therapy for the treatment of epilepsy: evidence to date
Shukla, N. D., Ho, A. L., Pendharkar, A. V., Sussman, E. S., & Halpern, C. H. (2017). Laser interstitial thermal therapy for the treatment of epilepsy: evidence to date. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 13, 2469–75. -
Diffusion MRI tractography for improved transcranial MRI-guided focused ultrasound thalamotomy targeting for essential tremor.
Tian, Q., Wintermark, M., Jeffrey Elias, W., Ghanouni, P., Halpern, C. H., Henderson, J. M., … McNab, J. A. (2018). Diffusion MRI tractography for improved transcranial MRI-guided focused ultrasound thalamotomy targeting for essential tremor. NeuroImage. Clinical, 19, 572–80. -
Frameless stereotactic dual lead placement through single burr hole: A technical report.
Cartmell, S. C., Miller, K. J., Ho, A. L., & Halpern, C. H. (2018). Frameless stereotactic dual lead placement through single burr hole: A technical report. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. -
Validity and Reliability of a Virtual Reality Game in Evaluating the Projected Frontal Plane Knee Angle When Landing From a Drop Vertical Jump.
Mills, K., Idris, A., Pham, T.-A., Porte, J., Wiggins, M., & Kavakli, M. (2018). Validity and Reliability of a Virtual Reality Game in Evaluating the Projected Frontal Plane Knee Angle When Landing From a Drop Vertical Jump. Journal of Sport Rehabilitation, 1–5. -
The nucleus accumbens and alcoholism: a target for deep brain stimulation
Ho, A. L., Salib, A.-M. N., Pendharkar, A., Sussman, E. S., Giardino, W. J., & Halpern, C. H. (2018). The nucleus accumbens and alcoholism: a target for deep brain stimulation. NEUROSURGICAL FOCUS, 45(2), E12. -
Robot-guided pediatric stereoelectroencephalography: single-institution experience.
Ho, A. L., Muftuoglu, Y., Pendharkar, A. V., Sussman, E. S., Porter, B. E., Halpern, C. H., & Grant, G. A. (2018). Robot-guided pediatric stereoelectroencephalography: single-institution experience. Journal of Neurosurgery. Pediatrics, 1–8. -
Stereoelectroencephalography in children: a review.
Ho, A. L., Feng, A. Y., Kim, L. H., Pendharkar, A. V., Sussman, E. S., Halpern, C. H., & Grant, G. A. (2018). Stereoelectroencephalography in children: a review. Neurosurgical Focus, 45(3), E7. -
Deep Brain Stimulation for Chronic Cluster Headache: A Review.
Vyas, D. B., Ho, A. L., Dadey, D. Y., Pendharkar, A. V., Sussman, E. S., Cowan, R., & Halpern, C. H. (2018). Deep Brain Stimulation for Chronic Cluster Headache: A Review. Neuromodulation : Journal of the International Neuromodulation Society. -
Laser interstitial thermal therapy (LITT): Seizure outcomes for refractory mesial temporal lobe epilepsy.
Le, S., Ho, A. L., Fisher, R. S., Miller, K. J., Henderson, J. M., Grant, G. A., … Halpern, C. H. (2018). Laser interstitial thermal therapy (LITT): Seizure outcomes for refractory mesial temporal lobe epilepsy. Epilepsy & Behavior : E&B, 89, 37–41. -
A novel mesial temporal stereotactic coordinate system.
Miller, K. J., Halpern, C. H., Sedrak, M. F., Duncan, J. A., & Grant, G. A. (2018). A novel mesial temporal stereotactic coordinate system. Journal of Neurosurgery, 1–9. -
Frameless Robot-Assisted Deep Brain Stimulation Surgery: An Initial Experience.
Ho, A. L., Pendharkar, A. V., Brewster, R., Martinez, D. L., Jaffe, R. A., Xu, L. W., … Halpern, C. H. (2019). Frameless Robot-Assisted Deep Brain Stimulation Surgery: An Initial Experience. Operative Neurosurgery (Hagerstown, Md.). -
Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study.
Kumar, K. K., Appelboom, G., Lamsam, L., Caplan, A. L., Williams, N. R., Bhati, M. T., … Halpern, C. H. (2019). Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study. Journal of Neurology, Neurosurgery, and Psychiatry. -
MR-Guided Focused Ultrasound Versus Radiofrequency Capsulotomy for Treatment-Refractory Obsessive-Compulsive Disorder: A Cost-Effectiveness Threshold Analysis
Kumar, K. K., Bhati, M. T., Ravikumar, V. K., Ghanouni, P., Stein, S. C., & Halpern, C. H. (2019). MR-Guided Focused Ultrasound Versus Radiofrequency Capsulotomy for Treatment-Refractory Obsessive-Compulsive Disorder: A Cost-Effectiveness Threshold Analysis. FRONTIERS IN NEUROSCIENCE, 13. -
MR-Guided Focused Ultrasound Versus Radiofrequency Capsulotomy for Treatment-Refractory Obsessive-Compulsive Disorder: A Cost-Effectiveness Threshold Analysis.
Kumar, K. K., Bhati, M. T., Ravikumar, V. K., Ghanouni, P., Stein, S. C., & Halpern, C. H. (2019). MR-Guided Focused Ultrasound Versus Radiofrequency Capsulotomy for Treatment-Refractory Obsessive-Compulsive Disorder: A Cost-Effectiveness Threshold Analysis. Frontiers in Neuroscience, 13, 66. -
Robust clinical benefit of multi-target deep brain stimulation for treatment of Gilles de la Tourette syndrome and its comorbidities.
Kakusa, B., Saluja, S., Tate, W. J., Espil, F. M., Halpern, C. H., & Williams, N. R. (2019). Robust clinical benefit of multi-target deep brain stimulation for treatment of Gilles de la Tourette syndrome and its comorbidities. Brain Stimulation. -
Attitudes Toward Treating Addiction With Deep Brain Stimulation.
Ali, R., DiFrancesco, M. F., Ho, A. L., Kampman, K. M., Caplan, A. L., & Halpern, C. H. (2016). Attitudes Toward Treating Addiction With Deep Brain Stimulation. Brain Stimulation, 9(3), 466–68. -
Letter: Electric Beats Open New Frontiers for Deep Brain Stimulation.
Halpern, C. H., Miller, K. J., Wu, H., & Tass, P. A. (2018). Letter: Electric Beats Open New Frontiers for Deep Brain Stimulation. Neurosurgery, 82(1), E19–E20. -
Responsive stimulation of motor cortex for medically and surgically refractive epilepsy.
Miller, K. J., Burns, T. C., Grant, G. A., & Halpern, C. H. (2015). Responsive stimulation of motor cortex for medically and surgically refractive epilepsy. Seizure, 33, 38–40. -
Deep Brain Stimulation Salvages a Flourishing Dental Practice: A Dentist with Essential Tremor Recounts his Experience.
Giacopuzzi, G., Lising, M., & Halpern, C. H. (2016). Deep Brain Stimulation Salvages a Flourishing Dental Practice: A Dentist with Essential Tremor Recounts his Experience. Cureus, 8(10), e840. -
Impact of skull density ratio on efficacy and safety of magnetic resonance-guided focused ultrasound treatment of essential tremor.
D'Souza, M., Chen, K. S., Rosenberg, J., Elias, W. J., Eisenberg, H. M., Gwinn, R., … Ghanouni, P. (2019). Impact of skull density ratio on efficacy and safety of magnetic resonance-guided focused ultrasound treatment of essential tremor. Journal of Neurosurgery, 1–6. -
Case Studies in Neuroscience: The electrophysiology of a human obsession in nucleus accumbens.
Miller, K. J., Prieto, T., Williams, N. R., & Halpern, C. H. (2019). Case Studies in Neuroscience: The electrophysiology of a human obsession in nucleus accumbens. Journal of Neurophysiology. -
Stereoelectroencephalography in children: a review
Ho, A. L., Feng, A. Y., Kim, L. H., Pendharkar, A. V., Sussman, E. S., Halpern, C. H., & Grant, G. A. (2018). Stereoelectroencephalography in children: a review. NEUROSURGICAL FOCUS, 45(3). -
Vocal Tremor: Novel Therapeutic Target for Deep Brain Stimulation
Ravikumar, V. K., Ho, A. L., Parker, J. J., Erickson-DiRenzo, E., & Halpern, C. H. (2016). Vocal Tremor: Novel Therapeutic Target for Deep Brain Stimulation. BRAIN SCIENCES, 6(4). -
Awake versus asleep deep brain stimulation for Parkinson's disease: a critical comparison and meta-analysis
Ho, A. L., Ali, R., Connolly, I. D., Henderson, J. M., Dhall, R., Stein, S. C., & Halpern, C. H. (2018). Awake versus asleep deep brain stimulation for Parkinson's disease: a critical comparison and meta-analysis. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 89(7), 687–91. -
Robust clinical benefit of multi-target deep brain stimulation for treatment of Gilles de la Tourette syndrome and its comorbidities
Kakusa, B., Saluja, S., Tate, W. J., Espil, F. M., Halpern, C. H., & Williams, N. R. (2019). Robust clinical benefit of multi-target deep brain stimulation for treatment of Gilles de la Tourette syndrome and its comorbidities. BRAIN STIMULATION, 12(3), 816–18. -
Robot guided pediatric stereoelectroencephalography: single-institution experience
Ho, A. L., Muftuoglu, Y., Pendharkar, A., Sussman, E. S., Porter, B. E., Halpern, C. H., & Grant, G. A. (2018). Robot guided pediatric stereoelectroencephalography: single-institution experience. JOURNAL OF NEUROSURGERY-PEDIATRICS, 22(5), 489–96. -
Multimodal characterization of the human nucleus accumbens.
Cartmell, S. C., Tian, Q., Thio, B. J., Leuze, C., Ye, L., Williams, N. R., … Halpern, C. H. (2019). Multimodal characterization of the human nucleus accumbens. NeuroImage. -
Diffusion MRI tractography for improved transcranial MRI-guided focused ultrasound thalamotomy targeting for essential tremor
Tian, Q., Wintermark, M., Elias, W. J., Ghanouni, P., Halpern, C. H., Henderson, J. M., … McNab, J. A. (2018). Diffusion MRI tractography for improved transcranial MRI-guided focused ultrasound thalamotomy targeting for essential tremor. NEUROIMAGE-CLINICAL, 19, 572–80. -
Novel application of virtual reality in patient engagement for deep brain stimulation: A pilot study
Collins, M. K., Ding, V. Y., Ball, R. L., Dolce, D. L., Henderson, J. M., & Halpern, C. H. (2018). Novel application of virtual reality in patient engagement for deep brain stimulation: A pilot study. BRAIN STIMULATION, 11(4), 935–37. -
Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: A multicenter study of 234 patients.
Wu, C., Jermakowicz, W. J., Chakravorti, S., Cajigas, I., Sharan, A. D., Jagid, J. R., … D'Haese, P.-F. (2019). Effects of surgical targeting in laser interstitial thermal therapy for mesial temporal lobe epilepsy: A multicenter study of 234 patients. Epilepsia. -
Deep Brain Stimulation for Obesity
Ho, A. L., Sussman, E. S., Zhang, M., Pendharkar, A. V., Azagury, D. E., Bohon, C., & Halpern, C. H. (2015). Deep Brain Stimulation for Obesity. CUREUS, 7(3). -
Hair sparing does not compromise real-time magnetic resonance imaging guided stereotactic laser fiber placement for temporal lobe epilepsy
Singh, S., Kumar, K. K., Rabon, M. J., Dolce, D., & Halpern, C. H. (2018). Hair sparing does not compromise real-time magnetic resonance imaging guided stereotactic laser fiber placement for temporal lobe epilepsy. JOURNAL OF CLINICAL NEUROSCIENCE, 52, 71–73. -
Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study
Kumar, K. K., Appelboom, G., Lamsam, L., Caplan, A. L., Williams, N. R., Bhati, M. T., … Halpern, C. H. (2019). Comparative effectiveness of neuroablation and deep brain stimulation for treatment-resistant obsessive-compulsive disorder: a meta-analytic study. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 90(4), 469–73. -
Deep Brain Stimulation for Chronic Cluster Headache: A Review
Vyas, D. B., Ho, A. L., Dadey, D. Y., Pendharkar, A. V., Sussman, E. S., Cowan, R., & Halpern, C. H. (2019). Deep Brain Stimulation for Chronic Cluster Headache: A Review. NEUROMODULATION, 22(4), 388–97. -
A novel mesial temporal stereotactic coordinate system
Miller, K. J., Halpern, C. H., Sedrak, M. F., Duncan, J. A., & Grant, G. A. (2019). A novel mesial temporal stereotactic coordinate system. JOURNAL OF NEUROSURGERY, 130(1), 67–75. -
Neuromodulatory Treatments for Alcohol Use Disorder: A Review
Salib, A.-M. N., Ho, A. L., Sussman, E. S., Pendharkar, A. V., & Halpern, C. H. (2018). Neuromodulatory Treatments for Alcohol Use Disorder: A Review. BRAIN SCIENCES, 8(6). -
Cognitive safety of intracranial electrodes for epilepsy
Meador, K. J., Halpern, C. H., & Hermann, B. P. (2018). Cognitive safety of intracranial electrodes for epilepsy. EPILEPSIA, 59(6), 1132–37. -
Magnetic Resonance-Guided Laser-Induced Thermal Therapy for Recurrent Brain Metastases in the Motor Strip After Stereotactic Radiosurgery
Iyer, A., Halpern, C. H., Grant, G. A., Deb, S., & Li, G. H. (2016). Magnetic Resonance-Guided Laser-Induced Thermal Therapy for Recurrent Brain Metastases in the Motor Strip After Stereotactic Radiosurgery. CUREUS, 8(12). -
Topical vancomycin surgical prophylaxis in pediatric open craniotomies: an institutional experience
Ho, A. L., Cannon, J. G. D., Mohole, J., Pendharkar, A., Sussman, E. S., Li, G., … Grant, G. A. (2018). Topical vancomycin surgical prophylaxis in pediatric open craniotomies: an institutional experience. JOURNAL OF NEUROSURGERY-PEDIATRICS, 22(6), 710–15. -
Multimodal characterization of the human nucleus accumbens
Cartmell, S. C. D., Tian, Q., Thio, B. J., Leuze, C., Ye, L., Williams, N. R., … Halpern, C. H. (2019). Multimodal characterization of the human nucleus accumbens. NEUROIMAGE, 198, 137–49. -
Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery.
Tekriwal, A., Afshar, N. M., Santiago-Moreno, J., Kuijper, F. M., Kern, D. S., Halpern, C. H., … Thompson, J. A. (2019). Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery. Brain Sciences, 9(7). -
Stereotactic laser ablation for completion corpus callosotomy.
Huang, Y., Yecies, D., Bruckert, L., Parker, J. J., Ho, A. L., Kim, L. H., … Grant, G. A. (2019). Stereotactic laser ablation for completion corpus callosotomy. Journal of Neurosurgery. Pediatrics, 1–9. -
Anatomic and Thermometric Analysis of Cranial Nerve Palsy after Laser Amygdalohippocampotomy for Mesial Temporal Lobe Epilepsy.
Huang, Y., Leung, S. A., Parker, J. J., Ho, A. L., Wintermark, M., Patel, S. H., … Halpern, C. H. (2019). Anatomic and Thermometric Analysis of Cranial Nerve Palsy after Laser Amygdalohippocampotomy for Mesial Temporal Lobe Epilepsy. Operative Neurosurgery (Hagerstown, Md.). -
Frameless Robot-Assisted Deep Brain Stimulation Surgery: An Initial Experience
Ho, A. L., Pendharkar, A. V., Brewster, R., Martinez, D. L., Jaffe, R. A., Xu, L. W., … Halpern, C. H. (2019). Frameless Robot-Assisted Deep Brain Stimulation Surgery: An Initial Experience. OPERATIVE NEUROSURGERY, 17(4), 424–31. -
Predictors of Outcomes After Focused Ultrasound Thalamotomy.
Krishna, V., Sammartino, F., Cosgrove, R., Ghanouni, P., Schwartz, M., Gwinn, R., … Halpern, C. (2019). Predictors of Outcomes After Focused Ultrasound Thalamotomy. Neurosurgery. -
Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor.
Halpern, C. H., Santini, V., Lipsman, N., Lozano, A. M., Schwartz, M. L., Shah, B. B., … Ghanouni, P. (2019). Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor. Neurology. -
Randomized Controlled Trials in Functional Neurosurgery-Association of Device Approval Status and Trial Quality.
Azad, T. D., Feng, A. Y., Mehta, S., Bak, A. B., Johnson, E., Mittal, V., … Grant, G. A. (2019). Randomized Controlled Trials in Functional Neurosurgery-Association of Device Approval Status and Trial Quality. Neuromodulation : Journal of the International Neuromodulation Society. -
Robot-assisted versus manual navigated stereoelectroencephalography in adult medically-refractory epilepsy patients.
Kim, L. H., Feng, A. Y., Ho, A. L., Parker, J. J., Kumar, K. K., Chen, K. S., … Halpern, C. H. (2019). Robot-assisted versus manual navigated stereoelectroencephalography in adult medically-refractory epilepsy patients. Epilepsy Research, 159, 106253. -
Adjunctive repetitive transcranial magnetic stimulation delivers superior quality of life for focal epilepsy compared to anti-epileptic drugs: A meta-analytic utility prediction study.
Mahajan, U. V., Parker, J. J., Williams, N. R., Bhati, M. T., Ku, S., Grant, G., … Halpern, C. H. (2019). Adjunctive repetitive transcranial magnetic stimulation delivers superior quality of life for focal epilepsy compared to anti-epileptic drugs: A meta-analytic utility prediction study. Brain Stimulation. -
Electrophysiological dynamics of antagonistic brain networks reflect attentional fluctuations.
Kucyi, A., Daitch, A., Raccah, O., Zhao, B., Zhang, C., Esterman, M., … Parvizi, J. (2020). Electrophysiological dynamics of antagonistic brain networks reflect attentional fluctuations. Nature Communications, 11(1), 325. -
Interobserver Agreement for the CT Severity Grading Scales for Acute Traumatic Brain Injury (TBI).
Creeden, S., Ding, V., Parker, J. J., Jiang, B., Li, Y., Lanzman, B., … Wintermark, M. (2020). Interobserver Agreement for the CT Severity Grading Scales for Acute Traumatic Brain Injury (TBI). Journal of Neurotrauma. -
Postoperative outcomes following pediatric intracranial electrode monitoring: A case for stereoelectroencephalography (SEEG).
Kim, L. H., Parker, J. J., Ho, A. L., Pendharkar, A. V., Sussman, E. S., Halpern, C. H., … Grant, G. A. (2020). Postoperative outcomes following pediatric intracranial electrode monitoring: A case for stereoelectroencephalography (SEEG). Epilepsy & Behavior : E&B, 104(Pt A), 106905. -
Utilization of Novel High-Resolution, MRI-Based Vascular Imaging Modality for Preoperative Stereoelectroencephalography Planning in Children: A Technical Note.
Feng, A. Y., Ho, A. L., Kim, L. H., Sussman, E. S., Pendharkar, A. V., Iv, M., … Grant, G. A. (2020). Utilization of Novel High-Resolution, MRI-Based Vascular Imaging Modality for Preoperative Stereoelectroencephalography Planning in Children: A Technical Note. Stereotactic and Functional Neurosurgery, 1–7. -
Intraoperative Evaluation of Essential Vocal Tremor in Deep Brain Stimulation Surgery.
Erickson-DiRenzo, E., Sung, C. K., Ho, A. L., & Halpern, C. H. (2020). Intraoperative Evaluation of Essential Vocal Tremor in Deep Brain Stimulation Surgery. American Journal of Speech-Language Pathology, 1–13. -
Deep Brain Stimulation Results in Greater Symptomatic Improvement in Tourette Syndrome than Conservative Measures: A Meta-Analysis.
Mahajan, U. V., Purger, D. A., Mantovani, A., Williams, N. R., Epsil, F. M., Han, S. S., … Halpern, C. H. (2020). Deep Brain Stimulation Results in Greater Symptomatic Improvement in Tourette Syndrome than Conservative Measures: A Meta-Analysis. Stereotactic and Functional Neurosurgery, 1–8. -
Letter: Using Continuous Intracranial Electroencephalography Monitoring to Manage Epilepsy Patients During COVID-19.
Mirro, E. A., & Halpern, C. H. (2020). Letter: Using Continuous Intracranial Electroencephalography Monitoring to Manage Epilepsy Patients During COVID-19. Neurosurgery. -
How Support of Early Career Researchers Can Reset Science in the Post-COVID19 World.
Gibson, E. M., Bennett, F. C., Gillespie, S. M., Guler, A. D., Gutmann, D. H., Halpern, C. H., … Zuchero, J. B. (2020). How Support of Early Career Researchers Can Reset Science in the Post-COVID19 World. Cell. -
Electrophysiology and Structural Connectivity of the Posterior Hypothalamic Region: Much to Learn From a Rare Indication of Deep Brain Stimulation.
Kakusa, B., Saluja, S., Dadey, D. Y., Barbosa, D. A., Gattas, S., Miller, K. J., … Halpern, C. H. (2020). Electrophysiology and Structural Connectivity of the Posterior Hypothalamic Region: Much to Learn From a Rare Indication of Deep Brain Stimulation. Frontiers in Human Neuroscience, 14, 164. -
Real-world experience with direct brain-responsive neurostimulation for focal onset seizures.
Razavi, B., Rao, V. R., Lin, C., Bujarski, K. A., Patra, S. E., Burdette, D. E., … Halpern, C. H. (2020). Real-world experience with direct brain-responsive neurostimulation for focal onset seizures. Epilepsia. -
Case Report on Deep Brain Stimulation Rescue After Suboptimal MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor: A Tractography-Based Investigation.
Saluja, S., Barbosa, D. A., Parker, J. J., Huang, Y., Jensen, M. R., Ngo, V., … Halpern, C. H. (2020). Case Report on Deep Brain Stimulation Rescue After Suboptimal MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor: A Tractography-Based Investigation. Frontiers in Human Neuroscience, 14, 191. -
Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study.
Wu, H., Adler, S., Azagury, D. E., Bohon, C., Safer, D. L., Barbosa, D. A., … Halpern, C. H. (2020). Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study. Neurosurgery. -
Deep Brain Stimulation for Pediatric Neuropsychiatric Disorders
Quon, J. L., Kim, L. H., Quon, C. A., Prolo, L. M., Grant, G. A., & Halpern, C. H. (2019). Deep Brain Stimulation for Pediatric Neuropsychiatric Disorders. NEUROTECHNOLOGY AND BRAIN STIMULATION IN PEDIATRIC PSYCHIATRIC AND NEURODEVELOPMENTAL DISORDERS, 237–52. -
Improved Vim targeting for focused ultrasound ablation treatment of essential tremor: A probabilistic and patient-specific approach.
Su, J. H., Choi, E. Y., Tourdias, T., Saranathan, M., Halpern, C. H., Henderson, J. M., … Rutt, B. K. (2020). Improved Vim targeting for focused ultrasound ablation treatment of essential tremor: A probabilistic and patient-specific approach. Human Brain Mapping. -
Rapid Eye Movement Sleep Behavior Disorder: Pathological Neural Circuits and Association with Parkinson's Disease
Kahn, L., Abosch, A., Kern, D. S., Kushida, C. A., Halpern, C. H., & Thompson, J. A. (2019). Rapid Eye Movement Sleep Behavior Disorder: Pathological Neural Circuits and Association with Parkinson's Disease. HANDBOOK OF SLEEP RESEARCH, VOL 30, 30, 723–30. -
Evidence for the role of the dorsal ventral lateral posterior thalamic nucleus connectivity in deep brain stimulation for Gilles de la Tourette syndrome.
Kakusa, B., Saluja, S., Barbosa, D. A., Cartmell, S., Espil, F. M., Williams, N. R., … Halpern, C. H. (2020). Evidence for the role of the dorsal ventral lateral posterior thalamic nucleus connectivity in deep brain stimulation for Gilles de la Tourette syndrome. Journal of Psychiatric Research, 132, 60–64. -
Multiparametric laryngeal assessment of the effect of thalamic deep brain stimulation on essential vocal tremor.
Erickson-DiRenzo, E., Kuijper, F. M., Barbosa, D. A., Lim, E. A., Lin, P. T., Lising, M. A., … Halpern, C. H. (2020). Multiparametric laryngeal assessment of the effect of thalamic deep brain stimulation on essential vocal tremor. Parkinsonism & Related Disorders, 81, 106–12. -
Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy?
Wu, H., Hariz, M., Visser-Vandewalle, V., Zrinzo, L., Coenen, V. A., Sheth, S. A., … Nuttin, B. (2020). Deep brain stimulation for refractory obsessive-compulsive disorder (OCD): emerging or established therapy? Molecular Psychiatry. -
Impact of skull density ratio on efficacy and safety of magnetic resonance-guided focused ultrasound treatment of essential tremor
D'Souza, M., Chen, K. S., Rosenberg, J., Elias, W. J., Eisenberg, H. M., Gwinn, R., … Ghanouni, P. (2020). Impact of skull density ratio on efficacy and safety of magnetic resonance-guided focused ultrasound treatment of essential tremor. JOURNAL OF NEUROSURGERY, 132(5), 1392–97. -
Lessons From George Floyd: Racial Inequalities in the Treatment of Parkinson's Disease.
Ojukwu, D. I., Andruska, K. M., & Halpern, C. H. (2020). Lessons From George Floyd: Racial Inequalities in the Treatment of Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society. -
Contemporaneous evaluation of patient experience, surgical strategy, and seizure outcomes in patients undergoing stereoelectroencephalography or subdural electrode monitoring.
Kim, L. H., Parker, J. J., Ho, A. L., Feng, A. Y., Kumar, K. K., Chen, K. S., … Halpern, C. H. (2020). Contemporaneous evaluation of patient experience, surgical strategy, and seizure outcomes in patients undergoing stereoelectroencephalography or subdural electrode monitoring. Epilepsia. -
Bilateral Deep Brain Stimulation is the Procedure to Beat for Advanced Parkinson Disease: A Meta-Analytic, Cost-Effective Threshold Analysis for Focused Ultrasound.
Mahajan, U. V., Ravikumar, V. K., Kumar, K. K., Ku, S., Ojukwu, D. I., Kilbane, C., … Halpern, C. H. (2020). Bilateral Deep Brain Stimulation is the Procedure to Beat for Advanced Parkinson Disease: A Meta-Analytic, Cost-Effective Threshold Analysis for Focused Ultrasound. Neurosurgery. -
Closing the Loop on Loss of Control Over Eating: From Mouse to Man
Halpern, C. (2020). Closing the Loop on Loss of Control Over Eating: From Mouse to Man. NEUROPSYCHOPHARMACOLOGY, 45(SUPPL 1), 11–12. -
Boundary-anchored neural mechanisms of location-encoding for self and others.
Stangl, M., Topalovic, U., Inman, C. S., Hiller, S., Villaroman, D., Aghajan, Z. M., … Suthana, N. (2020). Boundary-anchored neural mechanisms of location-encoding for self and others. Nature. -
Accumbens coordinated reset stimulation in mice exhibits ameliorating aftereffects on binge alcohol drinking.
Ho, A. L., Feng, A. Y., Barbosa, D. A., Wu, H., Smith, M. L., Malenka, R. C., … Halpern, C. H. (2021). Accumbens coordinated reset stimulation in mice exhibits ameliorating aftereffects on binge alcohol drinking. Brain Stimulation. -
Anticipatory human subthalamic area beta-band power responses to dissociable tastes correlate with weight gain.
Kakusa, B., Huang, Y., Barbosa, D. A., Feng, A., Gattas, S., Shivacharan, R., … Halpern, C. H. (2021). Anticipatory human subthalamic area beta-band power responses to dissociable tastes correlate with weight gain. Neurobiology of Disease, 105348. -
Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding.
Christoffel, D. J., Walsh, J. J., Heifets, B. D., Hoerbelt, P., Neuner, S., Sun, G., … Malenka, R. C. (2021). Input-specific modulation of murine nucleus accumbens differentially regulates hedonic feeding. Nature Communications, 12(1), 2135. -
Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson's Disease.
Pfeifer, K. J., Kromer, J. A., Cook, A. J., Hornbeck, T., Lim, E. A., Mortimer, B. J., … Tass, P. A. (2021). Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson's Disease. Frontiers in Physiology, 12, 624317. -
Coagulopathy in Spinal Surgery
Milby, A. H., Halpern, C. H., & Schuster, J. M. (2020). Coagulopathy in Spinal Surgery. ESSENTIALS OF NEUROSURGICAL ANESTHESIA & CRITICAL CARE: STRATEGIES FOR PREVENTION, EARLY DETECTION, AND SUCCESSFUL MANAGEMENT OF PERIOPERATIVE COMPLICATIONS, 2ND EDITION, 251–54. -
Comparison of Treatments for Cocaine Use Disorder Among Adults: A Systematic Review and Meta-analysis.
Bentzley, B. S., Han, S. S., Neuner, S., Humphreys, K., Kampman, K. M., & Halpern, C. H. (2021). Comparison of Treatments for Cocaine Use Disorder Among Adults: A Systematic Review and Meta-analysis. JAMA Network Open, 4(5), e218049. -
Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies.
Vedam-Mai, V., Deisseroth, K., Giordano, J., Lazaro-Munoz, G., Chiong, W., Suthana, N., … Okun, M. S. (2021). Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies. Frontiers in Human Neuroscience, 15, 644593.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy »
- Prospective, Longitudinal Study of the Natural History and Functional Status of Patients With Myotubular Myopathy (MTM) »
- Responsive Neurostimulation For Loss Of Control Eating »
Practice Locations
Stanford Neuroscience Health Center Stanford, CA
Stanford, CA
Stanford Neuroscience Health Center
213 Quarry Road
Stanford , CA 94305
Make An Appointment More Clinic Information » Getting Here »Deep Brain Stimulation Program Palo Alto, CA
Palo Alto, CA
Deep Brain Stimulation Program
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Comprehensive Epilepsy Program Palo Alto, CA
Palo Alto, CA
Comprehensive Epilepsy Program
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Movement Disorders Center Palo Alto, CA
Palo Alto, CA
Movement Disorders Center
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Facial Pain Program Redwood City, CA
Redwood City, CA
Facial Pain Program
450 Broadway Street, Pavilion A, 1st Floor
Redwood City , CA 94063
Make An Appointment More Clinic Information » Getting Here »Neurosurgery Program Palo Alto, CA
Palo Alto, CA
Neurosurgery Program
213 Quarry Road
Palo Alto , CA 94304
Make An Appointment More Clinic Information » Getting Here »Patient Reviews
(74 reviews)
I very much like my neurologist, Dr. Harrison and his assistant. They are friendly thorough and always address my concerns, recommend certain healthcare/ideas with me and always include me in any issues, concerns or treatment.
Dr. Halpern is an exceptional doctor - Very concerned about my needs, great skills as a surgeon, willing to spend as much time with me as needed. Traci Horwbock is also personable & talented.
Dr Halporn is superb in explaining & relating to patients, & he is a first-rate surgeon.
The give and take was not what it had been in the past. It was not comfortable & also seemed rushed.
extremely thorough exam
He seemed a little full of himself.
Very comfortable with Dr. Halpern.
Great experience.
Dr. Halpern is TERRIFIC - willing to spend as much time as needed. I felt that he had real concern for me & is brilliantly knowledgeable - explained in detail all pros & cons of prospective surgery.
Dr.Halpern was extremely helpful, courteous and kind. He understood my issues and health concerns.
I've had the best experience, and I wouldn't be here if the care provider and team weren't there 100%. I'll always be thankful for their knowledge and care! They are the best, and I wish them the best!!
Above and beyond in all regards!
Very informative.
Erica told me that Dr. Halpern would be in shortly. I waited over one hour before he saw me I called the clinic. When they answered, the person said they were looking at my file and MRI. I question why they hadn't looked at it earlier.
Great doctor, very patient, clear, and thoughtful.
Casey deserves 6's. His staff does, too.
Very knowledgeable, friendly, put me at ease!
Outgoing & friendly.
Beyond compare!
Dr. Halpern, Dr. Chen they are very excellent in his profession, and take care of patient also very nice.
Gave us lots of time to thoroughly comprehend the program recommended.
Dr. C. Harrison & his staff changed my life - fabulous.
Everyone in this office is amazing. I felt like there was plenty of time to get all of my questions answered. When I left the office I was well informed and ready to make decisions concerning treatment.
Good.
Good.
Stellar.
Explain very well the illnesses that we had they attended us with great care they are efficient.
Given more information than I could absorb i.e., very thorough.
Doctor and PA present in an excellent way. Very knowledgeable and caring.
Dr. Halpern was very informative. I didn't feel rushed as he listened and took his time 100%.
I have been referred neurosurgeon and Dr. Halpern, hands down has had kindest, best manner of any I've ever met. Very easy to talk to.
Whatever questions we had were answered.
It has been next to impossible to contact the care provider or his team to address problems following surgery. The care provider and his team seldom responded to messages and brushed off concerns and serious issues that arose. I have never been less happy with the support and concern shown when things went badly after surgery. It is shameful.
Everyone talked to us and made sure we felt we understood.
Already have recommended this surgeon!
Good.
Dr. Casey Halpern was great from beginning of my surgery to now (follow up). Everyone who was with me, during my surgery to now has been great!
I had more time to talk about my treatment for surgery and therapy.
High level treatment.
Dr. Halpern was nothing short of wonderful. He was extremely kind, knowledgeable, understanding, etc. I trust him to give me accurate and compassionate information.
I wish there would be more professionals like Dr. Halpern at Stanford Hospital, compassionate and humane towards patients who are in horrible chronic pain like myself. I wish there would be other patients like Dr. Halpern willing to take any case no matter how complicated it is, and not like other doctors who are just cherry pickers "taking only easy cases."
Dr. Halpern's first attempt to place wires of spinal cord stimulator was unsuccessful. His second attempt was only partially successful. I still have an unexplained puffiness on the spine.
Dr. Halpern was brilliant, insightful at identifying alternative diagnoses of my problems that other doctors had not considered. He did a great job of explaining his theories and solutions to us.
Very good and helpful.
Great doctor.
Dr. Halpern is a kind, caring neurosurgeon. He spent 1 hour explaining the problem and possible solutions. He is one of a kind!
Dr. Halpern gave us a thorough examination of the procedure. He answered all our questions and guided us to make the decision to have surgery.
Dr. Halpern is great! He spends as much time with me as I need and helps explore all options for treatment. I feel like he really pays attention to what is best for me and that his treatment plans are logical and thoughtful.
Very professional.
My experience both with Dr. Qian, Dr. Prasad, and Dr. Halpern were all incredibly helpful. I felt they all provided as much time as possible to me and made me feel better about my condition and potential ways of dealing with the issue.
If only this surgeon could be my full-time pain management provider - he's been amazing to work with!
I feel very blessed to be a Stanford patient!
Coagulations for their work and I will recommend.
I would rate Dr. Halpern much higher if possible! From our first visit, he is always very personable & keeps us at ease during difficult situations.
Dr. Halpern always makes us comfortable and spends as much time with us as needed. We have been through so much in the past two years and I can not imagine having any other surgeon, he cares so much and makes me feel safe before and after surgery.
Dr. Halpern is an amazing doctor. I feel like he really cares about my health. I am blessed he is my doctor.
All friendly an care!
/dr. Halpern is a young, brilliant doctor, who, in my opinion, will have an outstanding career in medicine.
Dr. Halpern is the best doctor I've seen in years! He spent more time with me than I expected. He explained my condition in great detail and showed me how he proposes to correct it, should I choose surgery in the future. He also explained the various spinal cord stimulators with me and suggested how to go about evaluating the options. The follow-up response after the visit was immediate.
Doctor Halpern is great!
Thorough and insightful review/analysis.
Dr Halpern really cared about my situation during the visit and took the time to get to know me and I could tell he was very interestered in my medical history before the visit. he even addressed emails I had beforehand visit so he was more prepared
I liked the care provider sharing some of his thoughts about his options approaching surgery. I understood that he had been thinking about my particular brain and the variety of choices he could make for the best results. I certainly felt I was seen as an individual by a skilled surgeon interested in more than the expected details of doing the surgery.
Great.
Dr. Halpern is a very kind, caring doctor who shows respect & caring and healed me with dignity in all my visits. He is the BEST!!
I feel very confident in Dr. Halpern's care.
Excellent.
Everyone from the cleaning people to the surgeon have been wonderful. I cannot say enough about Dr. Halpern or Lawrence his P.A.
I am very thankful for Dr. Halpern. His dedication & passion for helping others shines through in all he does.
He's the very best there is. Dr. Halpern Casey HMD.
Dr. Halpern is VERY patient oriented - excellent.
No bad experience.
Doctor Halpern was absolutely great!!! Thank you!!! Thank you!!!
Very impressed & pleased with Dr. Halpern & looking forward to working w/him.
View More »
Referring Physicians
PHYSICIAN HELPLINE
Phone: 1-866-742-4811
Fax: 650-320-9443
Monday – Friday, 8 a.m. – 5 p.m.
Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referring Physicians.
- Send referrals online
- View referral status
- Access medical records