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Martha Morrell, MD
Epilepsy specialist
Dr. Morrell has been actively involved in helping to bring new medical and device therapies to patients with epilepsy. Since 2004, she has been Chief Medical Officer at NeuroPace, a company that developed a responsive neurostimulator for treatment of medically uncontrolled partial seizures. She has authored or coauthored more than 150 publications.
Service to professional societies includes member of the Board of Directors of the American Epilepsy Society, member and Chair of the Board of the Epilepsy Foundation, member of the Council of the American Neurological Association and Chair of the Epilepsy Section of the American Academy of Neurology. She is an elected Ambassador for Epilepsy of the International League Against Epilepsy and received the American Epilepsy Society’s 2007 Service Award for outstanding leadership and service. She is the current President of the American Society for Experimental Neurotherapeutics.
Practice Areas
Professional Education
- Medical Education: Stanford University School of Medicine (1984) CA
- Residency: University of Pennsylvania Health System (1988) PA
- Internship: University of Pennsylvania Health System (1985) PA
- Fellowship: Graduate Hospital (Closed) (1990) PA
- Board Certification: American Board of Psychiatry and Neurology, Epilepsy (2013)
- Board Certification: American Board of Psychiatry and Neurology, Neurology (1989)
Publications
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Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study
McLean, M. J., Morrell, M. J., Willmore, L. J., Privitera, M. D., Faught, R. E., Holmes, G. L., … Rose-Legatt, A. (1999). Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study. EPILEPSIA, 40(7), 965–972. -
Epilepsy in women: the science of why it is special
Morrell, M. J. (1999). Epilepsy in women: the science of why it is special. NEUROLOGY, 53(4), S42–S48. -
Dosing to efficacy with neurontin: The STEPS trial
Morrell, M. J. (1999). Dosing to efficacy with neurontin: The STEPS trial. Presented at the Symposium on Neurontin - Expanding the Clinical Experience, CANNES,FRANCE: BLACKWELL PUBLISHING. -
Discriminating between epileptic and nonepileptic events: The utility of hypnotic seizure induction
Barry, J. J., Atzman, O., & Morrell, M. J. (2000). Discriminating between epileptic and nonepileptic events: The utility of hypnotic seizure induction. EPILEPSIA, 41(1), 81–84.
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The role of the intracarotid amobarbital procedure in evaluation of patients for epilepsy surgery
Spencer, D. C., Morrell, M. J., & Risinger, M. W. (2000). The role of the intracarotid amobarbital procedure in evaluation of patients for epilepsy surgery. EPILEPSIA, 41(3), 320–25.
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"The Scarlet E" - Epilepsy is still a burden
Morrell, M. J., & Pedley, T. A. (2000). "The Scarlet E" - Epilepsy is still a burden. NEUROLOGY, 54(10), 1882–1883.
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Efficacy of gabapentin as adjunctive therapy in a large, multicenter study
Morrell, M. J., McLean, M. J., Willmore, L. J., Privitera, M. D., Faught, R. E., Holmes, G. L., … Rose-Legatt, A. (2000). Efficacy of gabapentin as adjunctive therapy in a large, multicenter study. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 9(4), 241–248.
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Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design
Laxer, K., Blum, D., Abou-Khalil, B. W., Morrell, M. J., Lee, D. A., Data, J. L., & Monaghan, E. P. (2000). Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design. EPILEPSIA, 41(9), 1187–1194.
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Health issues for women with epilepsy: A descriptive survey to assess knowledge and awareness among healthcare providers
Morrell, M. J., Sarto, G. E., Shafer, P. O., Borda, E. A., Herzog, A., & Callanan, M. (2000). Health issues for women with epilepsy: A descriptive survey to assess knowledge and awareness among healthcare providers. JOURNAL OF WOMENS HEALTH & GENDER-BASED MEDICINE, 9(9), 959–965.
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Adverse effects of antiepileptic drugs on bone structure - Epidemiology, mechanisms and therapeutic implications
Pack, A. M., & Morrell, M. J. (2001). Adverse effects of antiepileptic drugs on bone structure - Epidemiology, mechanisms and therapeutic implications. CNS DRUGS, 15(8), 633–642.
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Structural brain abnormalities in patients with schizophrenia, epilepsy, and epilepsy with chronic interictal psychosis
Marsh, L., SULLIVAN, E. V., Morrell, M., Lim, K. O., & Pfefferbaum, A. (2001). Structural brain abnormalities in patients with schizophrenia, epilepsy, and epilepsy with chronic interictal psychosis. PSYCHIATRY RESEARCH-NEUROIMAGING, 108(1), 1–15.
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Future directions for epilepsy research
Jacobs, M. P., Fischbach, G. D., Davis, M. R., Dichter, M. A., Dingledine, R., Lowenstein, D. H., … Theodore, W. H. (2001). Future directions for epilepsy research. NEUROLOGY, 57(9), 1536–1542.
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Pregnancy and antiepileptic drugs.
Morrell, M. J. (2001). Pregnancy and antiepileptic drugs. Current Neurology and Neuroscience Reports, 1(4), 359–360.
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Women with epilepsy: current treatment strategies.
Karceski, S., & Morrell, M. J. (2002). Women with epilepsy: current treatment strategies. The Journal of Gender-Specific Medicine : JGSM : the Official Journal of the Partnership for Women's Health at Columbia, 5(5), 22–26.
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Epilepsy in women
Morrell, M. J. (2002). Epilepsy in women. AMERICAN FAMILY PHYSICIAN, 66(8), 1489–1494.
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Predictors of ovulatory failure in women with epilepsy
Morrell, M. J., Giudice, L., Flynn, K. L., Seale, C. G., Paulson, A. J., Done, S., … Sauer, M. V. (2002). Predictors of ovulatory failure in women with epilepsy. ANNALS OF NEUROLOGY, 52(6), 704–711.
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Antiepileptic medications for the treatment of epilepsy
Morrell, M. J. (2002). Antiepileptic medications for the treatment of epilepsy. SEMINARS IN NEUROLOGY, 22(3), 247–258.
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Treatment of women with epilepsy
Pack, A. M., & Morrell, M. J. (2002). Treatment of women with epilepsy. SEMINARS IN NEUROLOGY, 22(3), 289–297.
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Review of lamotrigine and its clinical applications in epilepsy
Choi, H., & Morrell, M. J. (2003). Review of lamotrigine and its clinical applications in epilepsy. EXPERT OPINION ON PHARMACOTHERAPY, 4(2), 243–251.
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Achieving best care for women with epilepsy.
Morrell, M. J. (2000). Achieving best care for women with epilepsy. Epilepsy & Behavior , 1(5), 299–300.
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Stigma and epilepsy.
Morrell, M. J. (2002). Stigma and epilepsy. Epilepsy & Behavior : E&B, 3(6S2), 21–25.
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Caring for People with Epilepsy: Resources for the Healthcare Provider.
Morrell, M. J. (2000). Caring for People with Epilepsy: Resources for the Healthcare Provider. Epilepsy & Behavior : E&B, 1(4), S21–S24.
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Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs
Pack, A. M., Olarte, L. S., Morrell, M. J., Flaster, E., Resor, S. R., & Shane, E. (2003). Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs. EPILEPSY & BEHAVIOR, 4(2), 169–174.
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Fenfluramine-Phentermine (Fen-Phen) and Seizures: Evidence for an Association.
Spencer, D. C., Hwang, J., & Morrell, M. J. (2000). Fenfluramine-Phentermine (Fen-Phen) and Seizures: Evidence for an Association. Epilepsy & Behavior : E&B, 1(6), 448–452.
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Reproductive and metabolic disorders in women with epilepsy
Morrell, M. J. (2003). Reproductive and metabolic disorders in women with epilepsy. Presented at the 5th European Congress on Epileptology, MADRID,SPAIN: WILEY-BLACKWELL PUBLISHING, INC.
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The KEEPER (TM)(1) trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study
Morrell, M. J., Leppik, I., French, J., Ferrendelli, J., Han, J., & Magnus, L. (2003). The KEEPER (TM)(1) trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study. EPILEPSY RESEARCH, 54(2-3), 153–161.
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Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy
Morrell, M. J., Isojarvi, J., Taylor, A. E., Dam, M., Ayala, R., Gomez, G., … Messenheimer, J. (2003). Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy. EPILEPSY RESEARCH, 54(2-3), 189–199.
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Working toward an epilepsy cure.
Morrell, M. J. (2003). Working toward an epilepsy cure. Current Neurology and Neuroscience Reports, 3(4), 323–324.
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HORMONES AND EPILEPSY THROUGH THE LIFETIME
Morrell, M. J. (1992). HORMONES AND EPILEPSY THROUGH THE LIFETIME. Presented at the 11TH ANNUAL MERRITT-PUTNAM SYMP ON EPILEPSY THROUGH LIFE : RECENT ADVANCES IN UNDERSTANDING AND TREATING EPILEPSY DURING PREGNANCY, CHILDHOOD, ADULTHOOD, AND OLD AGE, PHILADELPHIA,PA: LIPPINCOTT-RAVEN PUBL.
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Qualitative block design performance in epilepsy patients
Zipf-Williams, E. M., Shear, P. K., Strongin, D., Winegarden, B. J., & Morrell, M. J. (2000). Qualitative block design performance in epilepsy patients. ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 15(2), 149–157.
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Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial
Ferrendelli, J. A., French, J., Leppik, I., Morrell, M. J., Herbeuval, A., Han, J., & Magnus, L. (2003). Use of levetiracetam in a population of patients aged 65 years and older: a subset analysis of the KEEPER trial. EPILEPSY & BEHAVIOR, 4(6), 702–709.
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Epilepsy and bone health in adults
Pack, A. M., & Morrell, M. J. (2004). Epilepsy and bone health in adults. EPILEPSY & BEHAVIOR, 5, S24–S29.
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Folic Acid and Epilepsy.
Morrell, M. J. (2002). Folic Acid and Epilepsy. Epilepsy Currents / American Epilepsy Society, 2(2), 31–34.
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Reproductive disturbances in patients with epilepsy.
Morrell, M. J., & Montouris, G. D. (2004). Reproductive disturbances in patients with epilepsy. Cleveland Clinic Journal of Medicine, 71, S19–24.
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Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy
Hirsch, L. J., Weintraub, D., Buchsbaum, R., Spencer, H. T., Hager, M., Strake, T., … Morrell, M. J. (2004). Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. NEUROLOGY, 63(6), 1022–1026.
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Epilepsy: diagnosis and treatment in the 21st century.
Morrell, M. J. (2001). Epilepsy: diagnosis and treatment in the 21st century. CNS Spectrums, 6(9), 749-?
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Reproductive dysfunction in women with epilepsy: antiepileptic drug effects on sex-steroid hormones.
Morrell, M. J., Flynn, K. L., Seale, C. G., Done, S., Paulson, A. J., Flaster, E. R., & Ferin, M. (2001). Reproductive dysfunction in women with epilepsy: antiepileptic drug effects on sex-steroid hormones. CNS Spectrums, 6(9), 771-?
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Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy
Pack, A. M., Morrell, M. J., Marcus, R., Holloway, L., Flaster, E., Done, S., … Shane, E. (2005). Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy. ANNALS OF NEUROLOGY, 57(2), 252–257.
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Sexual dysfunction, sex steroid hormone abnormalities, and depression in women with epilepsy treated with antiepileptic drugs
Morrell, M. J., Flynn, K. L., Done, S., Flaster, E., Kalayjian, L., & Pack, A. M. (2005). Sexual dysfunction, sex steroid hormone abnormalities, and depression in women with epilepsy treated with antiepileptic drugs. EPILEPSY & BEHAVIOR, 6(3), 360–365.
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Sex-steroid hormones in women with epilepsy.
Jette, N., & Morrell, M. J. (2005). Sex-steroid hormones in women with epilepsy. American Journal of Electroneurodiagnostic Technology, 45(1), 36–48.
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Treatment of epilepsy in adults: expert opinion, 2005
Karceski, S., Morrell, M. J., & Carpenter, D. (2005). Treatment of epilepsy in adults: expert opinion, 2005. EPILEPSY & BEHAVIOR, 7, S1–S64.
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A NONINVASIVE PROTOCOL FOR ANTERIOR TEMPORAL LOBECTOMY
Sperling, M. R., OCONNOR, M. J., Saykin, A. J., Phillips, C. A., Morrell, M. J., BRIDGMAN, P. A., … GONATAS, N. (1992). A NONINVASIVE PROTOCOL FOR ANTERIOR TEMPORAL LOBECTOMY. NEUROLOGY, 42(2), 416–422.
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SPEECH DURING PARTIAL SEIZURES - INTRACRANIAL EEG CORRELATES
Morrell, M. J., Phillips, C. A., OCONNOR, M. J., & Sperling, M. R. (1991). SPEECH DURING PARTIAL SEIZURES - INTRACRANIAL EEG CORRELATES. EPILEPSIA, 32(6), 886–889.
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Responsive cortical stimulation for the treatment of epilepsy
Sun, F. T., Morrell, M. J., & Wharen, R. E. (2008). Responsive cortical stimulation for the treatment of epilepsy. NEUROTHERAPEUTICS, 5(1), 68–74.
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Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy
Pack, A. M., Morrell, M. J., Randall, A., McMahon, D. J., & Shane, E. (2008). Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy. NEUROLOGY, 70(18), 1586–93.
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Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine
Morrell, M. J., Hayes, F. J., Sluss, P. M., Adams, J. M., Bhatt, M., Ozkara, C., … Isojarvi, J. (2008). Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine. ANNALS OF NEUROLOGY, 64(2), 200–211.
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Intracranial Stimulation Therapy for Epilepsy
Skarpaas, T. L., & Morrell, M. J. (2009). Intracranial Stimulation Therapy for Epilepsy. NEUROTHERAPEUTICS, 6(2), 238–243.
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SEXUAL DYSFUNCTION IN EPILEPSY
Morrell, M. J. (1991). SEXUAL DYSFUNCTION IN EPILEPSY. EPILEPSIA, 32, S38–S45.
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Normal vitamin D and low free estradiol levels in women on enzyme-inducing antiepileptic drugs
Pack, A. M., Morrell, M. J., McMahon, D. J., & Shane, E. (2011). Normal vitamin D and low free estradiol levels in women on enzyme-inducing antiepileptic drugs. EPILEPSY & BEHAVIOR, 21(4), 453–458.
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Responsive cortical stimulation for the treatment of medically intractable partial epilepsy
Morrell, M. J. (2011). Responsive cortical stimulation for the treatment of medically intractable partial epilepsy. NEUROLOGY, 77(13), 1295–1304.
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THE INFLUENCE OF AGE AND CYCLING STATUS ON SEXUAL AROUSABILITY IN WOMEN
Morrell, M. J., DIXEN, J. M., Carter, C. S., & DAVIDSON, J. M. (1984). THE INFLUENCE OF AGE AND CYCLING STATUS ON SEXUAL AROUSABILITY IN WOMEN. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 148(1), 66–71.
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PREDICTIVE VALUE OF THE FIRST ICTAL RECORDING IN DETERMINING LOCALIZATION OF THE EPILEPTOGENIC REGION BY SCALP SPHENOIDAL EEG
Sum, J. M., & Morrell, M. J. (1995). PREDICTIVE VALUE OF THE FIRST ICTAL RECORDING IN DETERMINING LOCALIZATION OF THE EPILEPTOGENIC REGION BY SCALP SPHENOIDAL EEG. EPILEPSIA, 36(10), 1033–1040.
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OVULATORY FUNCTION IN EPILEPSY
CUMMINGS, L. N., Giudice, L., & Morrell, M. J. (1995). OVULATORY FUNCTION IN EPILEPSY. EPILEPSIA, 36(4), 355–359.
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INTRACEREBRAL INVOLVEMENT IN SCLERODERMA EN COUP DE SABRE - REPORT OF A CASE WITH NEUROPATHOLOGIC FINDINGS
Chung, M. H., Sum, J., Morrell, M. J., & Horoupian, D. S. (1995). INTRACEREBRAL INVOLVEMENT IN SCLERODERMA EN COUP DE SABRE - REPORT OF A CASE WITH NEUROPATHOLOGIC FINDINGS. ANNALS OF NEUROLOGY, 37(5), 679–81.
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CONTRIBUTIONS OF ANTERIOR CINGULATE CORTEX TO BEHAVIOUR
Devinsky, O., Morrell, M. J., & Vogt, B. A. (1995). CONTRIBUTIONS OF ANTERIOR CINGULATE CORTEX TO BEHAVIOUR. BRAIN, 118, 279–306.
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DIFFERENTIAL-DIAGNOSIS OF SEIZURES
Morrell, M. J. (1993). DIFFERENTIAL-DIAGNOSIS OF SEIZURES. NEUROLOGIC CLINICS, 11(4), 737–754.
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SEXUAL DYSFUNCTION IN PARTIAL EPILEPSY - A DEFICIT IN PHYSIOLOGICAL SEXUAL AROUSAL
Morrell, M. J., Sperling, M. R., Stecker, M., & Dichter, M. A. (1994). SEXUAL DYSFUNCTION IN PARTIAL EPILEPSY - A DEFICIT IN PHYSIOLOGICAL SEXUAL AROUSAL. NEUROLOGY, 44(2), 243–247.
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Functional MRI measurement of language lateralization in Wada-tested patients
Desmond, J. E., Sum, J. M., Wagner, A. D., Demb, J. B., Shear, P. K., Glover, G. H., … Morrell, M. J. (1995). Functional MRI measurement of language lateralization in Wada-tested patients. BRAIN, 118, 1411–1419.
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Cerebellar hemorrhage complicating temporal lobectomy - Report of four cases
Toczek, M. T., Morrell, M. J., Silverberg, G. A., & Lowe, G. M. (1996). Cerebellar hemorrhage complicating temporal lobectomy - Report of four cases. JOURNAL OF NEUROSURGERY, 85(4), 718–722.
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The new antiepileptic drugs and women: Efficacy, reproductive health, pregnancy, and fetal outcome
Morrell, M. J. (1996). The new antiepileptic drugs and women: Efficacy, reproductive health, pregnancy, and fetal outcome. Presented at the 3rd International Merritt-Putnam Symposium on New Antiepileptic Drugs - From Discovery to Practical Use: Clinical Directions for the Future, SYDNEY,AUSTRALIA: BLACKWELL PUBLISHING.
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Self-reported sexual function and sexual arousability in women with epilepsy
Morrell, M. J., & Guldner, G. T. (1996). Self-reported sexual function and sexual arousability in women with epilepsy. EPILEPSIA, 37(12), 1204–1210.
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Nocturnal penile tumescence and rigidity evaluation in men with epilepsy
Guldner, G. T., & Morrell, M. J. (1996). Nocturnal penile tumescence and rigidity evaluation in men with epilepsy. EPILEPSIA, 37(12), 1211–1214.
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Cortical and hippocampal volume deficits in temporal lobe epilepsy
Marsh, L., Morrell, M. J., Shear, P. K., SULLIVAN, E. V., Freeman, H., Marie, A., … Pfefferbaum, A. (1997). Cortical and hippocampal volume deficits in temporal lobe epilepsy. EPILEPSIA, 38(5), 576–87.
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Maximizing the health of women with epilepsy: Science and ethics in new drug development
Morrell, M. J. (1997). Maximizing the health of women with epilepsy: Science and ethics in new drug development. EPILEPSIA, 38, S32–S41.
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Gabapentin monotherapy .1. An 8-day, double-blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures
Bergey, G. K., MORRIS, H. H., Rosenfeld, W., Blume, W. T., Penovich, P. E., Morrell, M. J., … Pierce, M. (1997). Gabapentin monotherapy .1. An 8-day, double-blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures. NEUROLOGY, 49(3), 739–745.
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Issues for women in antiepileptic drug development.
Morrell, M. J. (1998). Issues for women in antiepileptic drug development. Advances in Neurology, 76, 149–159.
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Intracranial ictal recordings in mesial frontal lobe epilepsy
Toczek, M. T., Morrell, M. J., Risinger, M. W., & Shuer, L. (1997). Intracranial ictal recordings in mesial frontal lobe epilepsy. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 14(6), 499–506.
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Issues for women with epilepsy
Morrell, M. J. (1998). Issues for women with epilepsy. WESTERN JOURNAL OF MEDICINE, 168(4), 266–267.
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Management issues for women with epilepsy - A review of the literature
Zahn, C. A., Morrell, M. J., Collins, S. D., Labiner, D. M., & Yerby, M. S. (1998). Management issues for women with epilepsy - A review of the literature. NEUROLOGY, 51(4), 949–956.
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Analysis of prenatal and gestational care given to women with epilepsy
Seale, C. G., Morrell, M. J., Nelson, L., & Druzin, M. L. (1998). Analysis of prenatal and gestational care given to women with epilepsy. NEUROLOGY, 51(4), 1039–45.
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Guidelines for the care of women with epilepsy
Morrell, M. J. (1998). Guidelines for the care of women with epilepsy. NEUROLOGY, 51(5), S21–S27.
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Effects of epilepsy on women's reproductive health
Morrell, M. J. (1998). Effects of epilepsy on women's reproductive health. EPILEPSIA, 39, S32–S37.
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2005 update on the treatment of epilepsy: Survey of expert opinion
Karceski, S. C., Morrell, M. J., & Carpenter, D. (2005). 2005 update on the treatment of epilepsy: Survey of expert opinion. Presented at the 59th Annual Meeting of the American-Epilepsy-Society/American-Clinical-Neurophysiology-Society, WASHINGTON,DC: WILEY-BLACKWELL.
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INTERPERSONAL RELATIONSHIPS FOLLOWING TEMPORAL LOBECTOMY
CALLANAN, M. A., Barry, J. J., & Morrell, M. J. (1995). INTERPERSONAL RELATIONSHIPS FOLLOWING TEMPORAL LOBECTOMY. WILEY-BLACKWELL PUBLISHING, INC.
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THE USE OF HYPNOSIS FOR DIFFERENTIATING EPILEPTIC FROM NONEPILEPTIC EVENTS
Barry, J. J., Morrell, M. J., & Atzmon, O. (1995). THE USE OF HYPNOSIS FOR DIFFERENTIATING EPILEPTIC FROM NONEPILEPTIC EVENTS. WILEY-BLACKWELL PUBLISHING, INC.
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Linear scleroderma and intractable epilepsy: Neuropathologic evidence for a chronic inflammatory process - Reply
Horoupian, D. S., Morrell, M., Chung, M., & Sum, J. (1996). Linear scleroderma and intractable epilepsy: Neuropathologic evidence for a chronic inflammatory process - Reply. ANNALS OF NEUROLOGY, 39(2), 278–278.
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THE INFLUENCE OF AGE AND OVULATORY STATUS ON SEXUAL AROUSAL IN WOMEN
Morrell, M. J., DIXEN, J. M., CARTERPORGES, S., & DAVIDSON, J. M. (1983). THE INFLUENCE OF AGE AND OVULATORY STATUS ON SEXUAL AROUSAL IN WOMEN. CLINICAL RESEARCH, 31(1), A1–A1.
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MEMORY DURING INTRACAROTID SODIUM AMYTAL TESTING RELATES TO HIPPOCAMPAL BUT NOT EXTRAHIPPOCAMPAL VOLUMES IN TEMPORAL-LOBE EPILEPSY
Shear, P. K., Marsh, L., Morrell, M. J., & SULLIVAN, E. V. (1995). MEMORY DURING INTRACAROTID SODIUM AMYTAL TESTING RELATES TO HIPPOCAMPAL BUT NOT EXTRAHIPPOCAMPAL VOLUMES IN TEMPORAL-LOBE EPILEPSY. WILEY-BLACKWELL PUBLISHING, INC.
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Clinical symptoms and mri abnormalities in schizophrenia and in epilepsy
Marsh, L., Sullivan, E., Spears, S., Sung, T., Lim, K., Morrell, M., & Pfefferbaum, A. (1997). Clinical symptoms and mri abnormalities in schizophrenia and in epilepsy. SCHIZOPHRENIA RESEARCH, 24(1-2), 151–152.
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NEOCORTICAL GRAY-MATTER DEFICITS IN PATIENTS WITH EPILEPSY AND SCHIZOPHRENIA-LIKE SYNDROMES
Marsh, L., SULLIVAN, E. V., Sung, T., Morrell, M. J., & Pfefferbaum, A. (1995). NEOCORTICAL GRAY-MATTER DEFICITS IN PATIENTS WITH EPILEPSY AND SCHIZOPHRENIA-LIKE SYNDROMES. WILEY-BLACKWELL PUBLISHING, INC.
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Sensitivity of verbal paired associates learning to mesial temporal sclerosis
Thomander, D., Shear, P. K., Zeifert, P., Riley, N., Karzmark, P., Hostetter, G., … Morrell, M. J. (1999). Sensitivity of verbal paired associates learning to mesial temporal sclerosis. WILEY-BLACKWELL.
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The Expert Consensus Guideline Series Treatment of Epilepsy
Karceski, S., Morrell, M., & Carpenter, D. (2001). The Expert Consensus Guideline Series Treatment of Epilepsy. EPILEPSY & BEHAVIOR, 2(6), A1–A50.
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Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial
Heck, C. N., King-Stephens, D., Massey, A. D., Nair, D. R., Jobst, B. C., Barkley, G. L., … Morrell, M. J. (2014). Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial. EPILEPSIA, 55(3), 432–441.
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Long-term treatment with responsive brain stimulation in adults with refractory partial seizures
Bergey, G. K., Morrell, M. J., Mizrahi, E. M., Goldman, A., King-Stephens, D., Nair, D., … Seale, C. G. (2015). Long-term treatment with responsive brain stimulation in adults with refractory partial seizures. NEUROLOGY, 84(8), 810–17.
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Fenfluramine-Phentermine (Fen-Phen) and Seizures: Evidence for an Association
Spencer, D. C., Hwang, J., & Morrell, M. J. (2000). Fenfluramine-Phentermine (Fen-Phen) and Seizures: Evidence for an Association. EPILEPSY & BEHAVIOR, 1(6), 448–452.
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11TH ANNUAL MERRITT-PUTNAM SYMPOSIUM - EPILEPSY THROUGH LIFE - RECENT ADVANCES IN UNDERSTANDING AND TREATING EPILEPSY DURING PREGNANCY, CHILDHOOD, ADULTHOOD, AND OLD-AGE
Leppik, I. E., Shields, W. D., Lindhout, D., & Morrell, M. J. (1992). 11TH ANNUAL MERRITT-PUTNAM SYMPOSIUM - EPILEPSY THROUGH LIFE - RECENT ADVANCES IN UNDERSTANDING AND TREATING EPILEPSY DURING PREGNANCY, CHILDHOOD, ADULTHOOD, AND OLD-AGE. EPILEPSIA, 33, S62–S67.
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Endocrine and metabolic responses to long-term monotherapy with the antiepileptic drug valproate in the normally cycling rhesus monkey
Ferin, M., Morrell, M., Xiao, E. N., Kochan, L., Qian, F., Wright, T., & Sauer, M. (2003). Endocrine and metabolic responses to long-term monotherapy with the antiepileptic drug valproate in the normally cycling rhesus monkey. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 88(6), 2908–2915.
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The RNS System: responsive cortical stimulation for the treatment of refractory partial epilepsy
Sun, F. T., & Morrell, M. J. (2014). The RNS System: responsive cortical stimulation for the treatment of refractory partial epilepsy. EXPERT REVIEW OF MEDICAL DEVICES, 11(6), 563–572.
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Closed-loop Neurostimulation: The Clinical Experience
Sun, F. T., & Morrell, M. J. (2014). Closed-loop Neurostimulation: The Clinical Experience. NEUROTHERAPEUTICS, 11(3), 553–563.
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Quality of life and mood in patients with medically intractable epilepsy treated with targeted responsive neurostimulation
Meador, K. J., Kapur, R., Loring, D. W., Kanner, A. M., & Morrell, M. J. (2015). Quality of life and mood in patients with medically intractable epilepsy treated with targeted responsive neurostimulation. EPILEPSY & BEHAVIOR, 45, 242–47.
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Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography
King-Stephens, D., Mirro, E., Weber, P. B., Laxer, K. D., Van Ness, P. C., Salanova, V., … Morrell, M. J. (2015). Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography. EPILEPSIA, 56(6), 959–67.
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Seizure-free days observed in randomized placebo-controlled add-on trials with levetiracetam in partial epilepsy
Leppik, I., Morrell, M., Godfroid, P., & Arrigo, C. (2003). Seizure-free days observed in randomized placebo-controlled add-on trials with levetiracetam in partial epilepsy. EPILEPSIA, 44(10), 1350–1352.
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Differential neuropsychological outcomes following targeted responsive neurostimulation for partial-onset epilepsy
Loring, D. W., Kapur, R., Meador, K. J., & Morrell, M. J. (2015). Differential neuropsychological outcomes following targeted responsive neurostimulation for partial-onset epilepsy. EPILEPSIA, 56(11), 1836–44.
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Day-Night Patterns of Epileptiform Activity in 65 Patients With Long-Term Ambulatory Electrocorticography
Anderson, C. T., Tcheng, T. K., Sun, F. T., & Morrell, M. J. (2015). Day-Night Patterns of Epileptiform Activity in 65 Patients With Long-Term Ambulatory Electrocorticography. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 32(5), 406–12.
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Responsive Direct Brain Stimulation for Epilepsy.
Morrell, M. J., & Halpern, C. (2016). Responsive Direct Brain Stimulation for Epilepsy. Neurosurgery Clinics of North America, 27(1), 111–21.
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Closed-Loop Stimulation in the Control of Focal Epilepsy of Insular Origin
Smith, J. R., Fountas, K. N., Murro, A. M., Park, Y. D., Jenkins, P. D., Morrell, M., … Greene, D. (2010). Closed-Loop Stimulation in the Control of Focal Epilepsy of Insular Origin. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 88(5), 281–287.
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Long-Term Measurement of Impedance in Chronically Implanted Depth and Subdural Electrodes During Responsive Neurostimulation in Humans
Sillay, K. A., Rutecki, P., Cicora, K., Worrell, G., Drazkowski, J., Shih, J. J., … Wingeier, B. (2013). Long-Term Measurement of Impedance in Chronically Implanted Depth and Subdural Electrodes During Responsive Neurostimulation in Humans. BRAIN STIMULATION, 6(5), 718–26.
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In response: The RNS System multicenter randomized double-blinded controlled trial of responsive cortical stimulation for adjunctive treatment of intractable partial epilepsy: Knowledge and insights gained
Morrell, M. J. (2014). In response: The RNS System multicenter randomized double-blinded controlled trial of responsive cortical stimulation for adjunctive treatment of intractable partial epilepsy: Knowledge and insights gained. EPILEPSIA, 55(9), 1470–71.
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Brain-responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy.
Geller, E. B., Skarpaas, T. L., Gross, R. E., Goodman, R. R., Barkley, G. L., Bazil, C. W., … Morrell, M. J. (2017). Brain-responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy. Epilepsia, 58(6), 994–1004.
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Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas.
Jobst, B. C., Kapur, R., Barkley, G. L., Bazil, C. W., Berg, M. J., Bergey, G. K., … Morrell, M. J. (2017). Brain-responsive neurostimulation in patients with medically intractable seizures arising from eloquent and other neocortical areas. Epilepsia, 58(6), 1005–14.
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Changes in the electrocorticogram after implantation of intracranial electrodes in humans: The implant effect
Sun, F. T., Desai, S. A., Tcheng, T. K., & Morrell, M. J. (2018). Changes in the electrocorticogram after implantation of intracranial electrodes in humans: The implant effect. CLINICAL NEUROPHYSIOLOGY, 129(3), 676–86.
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Infection and Erosion Rates in Trials of a Cranially Implanted Neurostimulator Do Not Increase with Subsequent Neurostimulator Placements
Weber, P. B., Kapur, R., Gwinn, R. P., Zimmerman, R. S., Courtney, T. A., & Morrell, M. J. (2017). Infection and Erosion Rates in Trials of a Cranially Implanted Neurostimulator Do Not Increase with Subsequent Neurostimulator Placements. STEREOTACTIC AND FUNCTIONAL NEUROSURGERY, 95(5), 325–29.
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linical and electrocorticographic response to antiepileptic drugs in patients treated with responsive stimulation
Skarpaas, T. L., Tcheng, T. K., & Morrell, M. J. (2018). linical and electrocorticographic response to antiepileptic drugs in patients treated with responsive stimulation. EPILEPSY & BEHAVIOR, 83, 192–200.
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Electrographic Correlates of Clinical Seizures
Desai, S. A., Tcheng, T., & Morrell, M. (2018). Electrographic Correlates of Clinical Seizures. NEUROLOGY, 90.
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Fetal antiepileptic drug exposure and learning and memory functioning at 6?years of age: The NEAD prospective observational study.
Cohen, M. J., Meador, K. J., May, R., Loblein, H., Conrad, T., Baker, G. A., … Loring, D. W. (2019). Fetal antiepileptic drug exposure and learning and memory functioning at 6?years of age: The NEAD prospective observational study. Epilepsy & Behavior : E&B, 92, 154–64.
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Brain-responsive neurostimulation for epilepsy (RNS System).
Skarpaas, T. L., Jarosiewicz, B., & Morrell, M. J. (2019). Brain-responsive neurostimulation for epilepsy (RNS System). Epilepsy Research.
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Response: Therapeutic brain-responsive neurostimulation in eloquent cortex can be delivered without symptoms.
Jobst, B. C., Skarpaas, T. L., & Morrell, M. J. (2017). Response: Therapeutic brain-responsive neurostimulation in eloquent cortex can be delivered without symptoms. Epilepsia, 58(8), 1488.
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Brain stimulation for epilepsy: can scheduled or responsive neurostimulation stop seizures?
Morrell, M. (2006). Brain stimulation for epilepsy: can scheduled or responsive neurostimulation stop seizures? Current Opinion in Neurology, 19(2), 164–68.
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Brain-responsive neurostimulation for epilepsy (RNS (R) System)
Skarpaas, T. L., Jarosiewicz, B., & Morrell, M. J. (2019). Brain-responsive neurostimulation for epilepsy (RNS (R) System). EPILEPSY RESEARCH, 153, 68–70.
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Treatment of drug-resistant epilepsy in patients with periventricular nodular heterotopia using RNS® System: Efficacy and description of chronic electrophysiological recordings.
Nune, G., Arcot Desai, S., Razavi, B., Agostini, M. A., Bergey, G. K., Herekar, A. A., … Morrell, M. J. (2019). Treatment of drug-resistant epilepsy in patients with periventricular nodular heterotopia using RNS® System: Efficacy and description of chronic electrophysiological recordings. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, 130(8), 1196–1207.
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Quantitative electrocorticographic biomarkers of clinical outcomes in mesial temporal lobe epileptic patients treated with the RNS system.
Arcot Desai, S., Tcheng, T. K., & Morrell, M. J. (2019). Quantitative electrocorticographic biomarkers of clinical outcomes in mesial temporal lobe epileptic patients treated with the RNS system. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology, 130(8), 1364–74.
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Nine-year Prospective Safety and Effectiveness Outcomes from the Long-Term Treatment Trial of the RNS (R) System
Nair, D., & Morrell, M. (2019). Nine-year Prospective Safety and Effectiveness Outcomes from the Long-Term Treatment Trial of the RNS (R) System. NEUROLOGY, 92(15).
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Mesial temporal resection following long-term ambulatory intracranial EEG monitoring with a direct brain-responsive neurostimulation system.
Hirsch, L. J., Mirro, E. A., Salanova, V., Witt, T. C., Drees, C. N., Brown, M.-G., … Morrell, M. J. (2020). Mesial temporal resection following long-term ambulatory intracranial EEG monitoring with a direct brain-responsive neurostimulation system. Epilepsia.
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Electrocorticographic events from long-term ambulatory brain recordings can potentially supplement seizure diaries.
Quigg, M., Skarpaas, T. L., Spencer, D. C., Fountain, N. B., Jarosiewicz, B., & Morrell, M. J. (2020). Electrocorticographic events from long-term ambulatory brain recordings can potentially supplement seizure diaries. Epilepsy Research, 161, 106302.
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Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy.
Nair, D. R., Laxer, K. D., Weber, P. B., Murro, A. M., Park, Y. D., Barkley, G. L., … Morrell, M. J. (2020). Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy. Neurology.
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Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study.
Wu, H., Adler, S., Azagury, D. E., Bohon, C., Safer, D. L., Barbosa, D. A., … Halpern, C. H. (2020). Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study. Neurosurgery.
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Mood and Quality of Life in Patients Treated with Brain-responsive Neurostimulation: The Value of Earlier Intervention
Loring, D., Jarosiewicz, B., Meador, K., Kanner, A., Skarpaas, T., & Morrell, M. (2020). Mood and Quality of Life in Patients Treated with Brain-responsive Neurostimulation: The Value of Earlier Intervention. NEUROLOGY, 94(15).
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The RNS System: brain-responsive neurostimulation for the treatment of epilepsy.
Jarosiewicz, B., & Morrell, M. (2020). The RNS System: brain-responsive neurostimulation for the treatment of epilepsy. Expert Review of Medical Devices, 1–10.
Patient Comments
Patients comments are gathered from our Patient Satisfaction Survey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
SHC Patient, Oct 2020
Dr. Morrell didn't rush anything, and was careful to explain everything.
SHC Patient, Sep 2020
Dr. Morrell is a very kind and compassionate person. She cares very much about making me well and provides the best care to do so. I'm very fortunate that she's my physician.
SHC Patient, Jun 2020
Dr. Morrell's care, compassion and expertise are excellent and first class! I would recommend her to anyone and trust her with my family any time!
SHC Patient, May 2020
Dr. seemed rushed due to prior emergency.
SHC Patient, Mar 2020
I always leave feeling well cared for and informed.
SHC Patient, Jan 2020
Dr. Morrell always takes a lot of time explaining my medical condition and how it is being monitored and treated through the RNs and medications.
SHC Patient, Dec 2019
Loved Dr. Morrell.
SHC Patient, Oct 2019
Dr. Morrell is an excellent physician. She is knowledgeable and an expert in her field and has care and compassion for her patients.
SHC Patient, Sep 2019
Dr. Morrell is AMAZING!!! She is combines her knowledge, involving many areas of neurology and combines them in a way that I can easily comprehend. She always spends a lot of time to be sure my questions are answered answered.
SHC Patient, Jun 2019
Dr. Morrell has been my incredible epileptologist for 20 years!! Mimi Callanan, and Dr. Morrell have been an absolute blessing.
SHC Patient, Jun 2019
Care provider was pushing me to change my medication on previous visits. She didn't seem interested in discussing medication change this time. No explanation offered.
SHC Patient, Apr 2019
Dr. Morrell is a gentle, caring very intelligent person. I trust her with all of my needs. The quality of my life is in her hands and she has made my life better I am fortunate that she is my doctor!
SHC Patient, Mar 2019
Dr. Morrell is a very caring & knowledgeable doctor. She treated me like her own daughter. I'm so happy she is my doctor!
SHC Patient, Dec 2018
Dr. Morrell assures me, through her care and concern, that I'm being treated by the best, that's my opinion!
SHC Patient, Dec 2018
Dr. Morrell is very kind and compassionate. She takes the time to explain all questions and concerns, treatments. I feel that she is the best doctor that a patient could want and need.
SHC Patient, Nov 2018
Very good.
SHC Patient, Aug 2018
Always the best!
SHC Patient, Aug 2018
Thank you for helping me when no one else would.
SHC Patient, Apr 2018
I am very grateful to Dr. Morrell for her help. Thank you! I feel very lucky. She has spent a great deal of time helping me.
SHC Patient, Mar 2018
Dr. Morrell has been wonderful at helping me, and treating my issues. I have great confidence in her ability to care for me, and have already recommend her to a friend.
SHC Patient, Feb 2018
Dr. Morrelli is very caring, compassionate and careful to explain and answer questions, treatment, options, etc., in a manner that is easy to understand. She spends a great amount of time to ensure this.
SHC Patient, Oct 2017
All the personnel very attentive thank you very much.
SHC Patient, Jul 2017
I would recommend her to as many friends and family. I would even try to make commercials of her on TV, so people know where she's located at!!
SHC Patient, Mar 2017
All good.
SHC Patient, Dec 2016
I am always amazed at how Dr. Morrell gives us the time we need despite a heavy schedule. It's really appreciated.
SHC Patient, Oct 2016
Mimi Calahan & Dr. Morrell work very hard for their patients. I am impressed & very thankful.
SHC Patient, Sep 2016
I feel very fortunate to have Dr. Morrell as my doctor - I have full confidence in Dr. Morrell and I rave about her to everyone!
SHC Patient, Aug 2016
Wow - Dr. Morrell is outstanding. Felt as if she had all the time in the world for me. She really listened & reviewed my input & medical records thoroughly.
SHC Patient, Aug 2016
Dr. Morrell is incredible- I feel so lucky to have her as my neurologist.
SHC Patient, Jul 2016
One of the most incredible physicians I have ever met. I wish I could see her all the time.
SHC Patient, Jun 2016
Best - ever - doctor she gave me details about my issue that helped me understand much better!
SHC Patient, Mar 2016
She was kind, heard me, believed me & was kind to me.
SHC Patient, Feb 2016
I am grateful for Dr. Morrell. She helps me so much.
SHC Patient, Feb 2016
Dr. Morrell is smart and kind and I feel cared for. She really listens to me and I trust her.
SHC Patient, Nov 2015
Showed and explained what could happen if testings were not done, kind and very caring.
SHC Patient, Sep 2015
Dr. Morrell gives excellent, expert, compassionate, skillful care.
SHC Patient, Sep 2015
Though pressed for time, she showed me how the seizures were seen remotely by her (and she had obviously personally poured over them). I wanted the information on, but would not have asked for it.
SHC Patient, Aug 2015
Dr. Morrell is an amazing doctor.
SHC Patient, Jul 2015
She was very explanatory and down to earth on what need to be tested next before possible surgery to brain aneurysm.
SHC Patient, May 2015
Great.
SHC Patient, Apr 2015
Very good.
SHC Patient, Jan 2015
Enjoyed chatting about other things other than the medical condition.
SHC Patient, Nov 2014
Advice given was bias toward dr.'s ideas & care. Info not correct.
SHC Patient, Sep 2014
New medications, not given much information about effects on 73 lbs. adult.
SHC Patient, Aug 2014
I LOVE Dr. Morrell! She is amazing!
SHC Patient, Jun 2014
Good.
SHC Patient, May 2014
Very caring, informative, & positive doctor & staff e-mails were answered quickly.
SHC Patient, Apr 2014
Dr. Morrell is very good.
SHC Patient, Feb 2014
Knowledgeable, courteous, very willing to explain what/why she was doing. If my last doctor was like this I would go more regularly - Dr. Morrell made this trip (and cost) worthwhile.
SHC Patient, Oct 2020
Dr. Morrell didn't rush anything, and was careful to explain everything.
SHC Patient, Sep 2020
Dr. Morrell is a very kind and compassionate person. She cares very much about making me well and provides the best care to do so. I'm very fortunate that she's my physician.
SHC Patient, Jun 2020
Dr. Morrell's care, compassion and expertise are excellent and first class! I would recommend her to anyone and trust her with my family any time!
SHC Patient, May 2020
Dr. seemed rushed due to prior emergency.
SHC Patient, Mar 2020
I always leave feeling well cared for and informed.
SHC Patient, Jan 2020
Dr. Morrell always takes a lot of time explaining my medical condition and how it is being monitored and treated through the RNs and medications.
SHC Patient, Dec 2019
Loved Dr. Morrell.
SHC Patient, Oct 2019
Dr. Morrell is an excellent physician. She is knowledgeable and an expert in her field and has care and compassion for her patients.
SHC Patient, Sep 2019
Dr. Morrell is AMAZING!!! She is combines her knowledge, involving many areas of neurology and combines them in a way that I can easily comprehend. She always spends a lot of time to be sure my questions are answered answered.
SHC Patient, Jun 2019
Dr. Morrell has been my incredible epileptologist for 20 years!! Mimi Callanan, and Dr. Morrell have been an absolute blessing.
SHC Patient, Jun 2019
Care provider was pushing me to change my medication on previous visits. She didn't seem interested in discussing medication change this time. No explanation offered.
SHC Patient, Apr 2019
Dr. Morrell is a gentle, caring very intelligent person. I trust her with all of my needs. The quality of my life is in her hands and she has made my life better I am fortunate that she is my doctor!
View All 49 Patient Comments »