Biography
Professional Summary
Education & Certifications
- Board Certification: American Board of Internal Medicine, Rheumatology (2013)
- Board Certification, American Board of Internal Medicine, Rheumatology
- Fellowship, Stanford University, Rheumatology
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- Residency, UCSF, Internal Medicine
Administrative Appointments
- Chief, Division of Immunology and Rheumatology, Stanford University (2019 - Present)
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Publications
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Demyelinating and neurologic events reported in association with tumor necrosis factor alpha antagonism - By what mechanisms could tumor necrosis factor alpha antagonists improve rheumatoid arthritis but exacerbate multiple sclerosis?
Robinson, W. H., Genovese, M. C., & Moreland, L. W. (2001). Demyelinating and neurologic events reported in association with tumor necrosis factor alpha antagonism - By what mechanisms could tumor necrosis factor alpha antagonists improve rheumatoid arthritis but exacerbate multiple sclerosis? ARTHRITIS AND RHEUMATISM, 44(9), 1977–1983. -
Autoantigen microarrays for multiplex characterization of autoantibody responses
Robinson, W. H., DiGennaro, C., Hueber, W., Haab, B. B., KAMACHI, M., Dean, E. J., … Utz, P. J. (2002). Autoantigen microarrays for multiplex characterization of autoantibody responses. NATURE MEDICINE, 8(3), 295–301. -
Proteomics technologies for the study of autoimmune disease
Robinson, W. H., Steinman, L., & Utz, P. J. (2002). Proteomics technologies for the study of autoimmune disease. ARTHRITIS AND RHEUMATISM, 46(4), 885–93. -
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Millennium Award. Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease.
Robinson, W. H., Garren, H., Utz, P. J., & Steinman, L. (2002). Millennium Award. Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease. Clinical Immunology , 103(1), 7–12. -
Autoantibody profiling for the study and treatment of autoimmune disease
Hueber, W., Utz, P. J., Steinman, L., & Robinson, W. H. (2002). Autoantibody profiling for the study and treatment of autoimmune disease. ARTHRITIS RESEARCH, 4(5), 290–95. -
Protein and peptide array analysis of autoimmune disease
Robinson, W. H., Steinman, L., & Utz, P. J. (2002). Protein and peptide array analysis of autoimmune disease. BIOTECHNIQUES, 66–69. -
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
Robinson, W. H., Fontoura, P., Lee, B. J., de Vegvar, H. E. N., Tom, J., Pedotti, R., … Steinman, L. (2003). Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. NATURE BIOTECHNOLOGY, 21(9), 1033–39. -
Microarray profiling of antibody responses against simian-human immunodeficiency virus: Postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen
de Vegvar, H. E. N., Amara, R. R., Steinman, L., Utz, P. J., Robinson, H. L., & Robinson, W. H. (2003). Microarray profiling of antibody responses against simian-human immunodeficiency virus: Postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen. JOURNAL OF VIROLOGY, 77(20), 11125–38. -
Protein arrays for autoantibody profiling and fine-specificity mapping
Robinson, W. H., Steinman, L., & Utz, P. J. (2003). Protein arrays for autoantibody profiling and fine-specificity mapping. PROTEOMICS, 3(11), 2077–84. -
Genomic and proteomic analysis of multiple sclerosis - Opinion
Robinson, W. H., Utz, P. J., & Steinman, L. (2003). Genomic and proteomic analysis of multiple sclerosis - Opinion. CURRENT OPINION IN IMMUNOLOGY, 15(6), 660–67. -
Autoantibodies in early arthritis: Advances in diagnosis and prognostication
Hueber, W., Utz, P. J., & Robinson, W. H. (2003). Autoantibodies in early arthritis: Advances in diagnosis and prognostication. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 21(5), S59–S64. -
Unlocking the "PAD" lock on rheumatoid arthritis
Utz, P. J., Genovese, M. C., & Robinson, W. H. (2004). Unlocking the "PAD" lock on rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES, 63(4), 330–32. -
Microarray profiling of antiviral antibodies for the development of diagnostics, vaccines, and therapeutics
de Vegvar, H. E. N., & Robinson, W. H. (2004). Microarray profiling of antiviral antibodies for the development of diagnostics, vaccines, and therapeutics. CLINICAL IMMUNOLOGY, 111(2), 196–201. -
Characterization of novel antigens recognized by serum autoantibodies from anti-CD1 TCR-transgenic lupus mice
Hueber, W., Zeng, D. F., Sharpe, O., Robinson, W. H., Strober, S., & Utz, P. J. (2004). Characterization of novel antigens recognized by serum autoantibodies from anti-CD1 TCR-transgenic lupus mice. EUROPEAN JOURNAL OF IMMUNOLOGY, 34(6), 1654–62. -
High-throughput methods for measuring autoantibodies in systemic lupus erythematosus and other autoimmune diseases
Graham, K. L., Robinson, W. H., Steinman, L., & Utz, P. J. (2004). High-throughput methods for measuring autoantibodies in systemic lupus erythematosus and other autoimmune diseases. AUTOIMMUNITY, 37(4), 269–72. -
Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis
Fontoura, P., Ho, P. P., DeVoss, J., Zheng, B. H., Lee, B. J., Kidd, B. A., … Steinman, L. (2004). Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. JOURNAL OF IMMUNOLOGY, 173(11), 6981–92. -
Antigen microarray profiling of autoantibodies in rheumatoid arthritis
Hueber, W., Kidd, B. A., Tomooka, B. H., Lee, B. J., Bruce, B., Fries, J. F., … Robinson, W. H. (2005). Antigen microarray profiling of autoantibodies in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(9), 2645–55. -
A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease
Ho, P. P., Fontoura, P., Platten, M., Sobel, R. A., DeVoss, J. J., Lee, L. Y., … Steinman, L. (2005). A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease. JOURNAL OF IMMUNOLOGY, 175(9), 6226–34. -
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite
Platten, M., Ho, P. P., Youssef, S., Fontoura, P., Garren, H., Hur, E. M., … Steinman, L. (2005). Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. SCIENCE, 310(5749), 850–55. -
Suppression of autoimmunity via microbial mimics of altered peptide ligands
Steinman, L., Utz, P. J., & Robinson, W. H. (2005). Suppression of autoimmunity via microbial mimics of altered peptide ligands. MOLECULAR MIMICRY: INFECTION-INDUCING AUTOIMMUNE DISEASE, 296, 55–63. -
Lipid microarrays identify key mediators of autoimmune brain inflammation
Kanter, J. L., Narayana, S., Ho, P. P., Catz, I., Warren, K. G., Sobel, R. A., … Robinson, W. H. (2006). Lipid microarrays identify key mediators of autoimmune brain inflammation. NATURE MEDICINE, 12(1), 138–43. -
EXTENSIVE POLYMORPHISM IN THE EXTRACELLULAR DOMAIN OF THE MOUSE B-CELL DIFFERENTIATION ANTIGEN LYB-2/CD72
Robinson, W. H., Ying, H., Miceli, M. C., & Parnes, J. R. (1992). EXTENSIVE POLYMORPHISM IN THE EXTRACELLULAR DOMAIN OF THE MOUSE B-CELL DIFFERENTIATION ANTIGEN LYB-2/CD72. JOURNAL OF IMMUNOLOGY, 149(3), 880–886. -
Antigen arrays for antibody profiling
Robinson, W. H. (2006). Antigen arrays for antibody profiling. CURRENT OPINION IN CHEMICAL BIOLOGY, 10(1), 67–72. -
Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis
Kuhn, K. A., Kulik, L., Tomooka, B., Braschler, K. J., Arend, W. P., Robinson, W. H., & Holers, V. M. (2006). Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis. JOURNAL OF CLINICAL INVESTIGATION, 116(4), 961–73. -
Fluid supported lipid bilayers containing mono sialoganglioside GM1: A QCM-D and FRAP study
Weng, K. C., Kanter, J. L., Robinson, W. H., & Frank, C. W. (2006). Fluid supported lipid bilayers containing mono sialoganglioside GM1: A QCM-D and FRAP study. COLLOIDS AND SURFACES B-BIOINTERFACES, 50(1), 76–84. -
Proteomic biomarkers for autoimmune disease
Hueber, W., & Robinson, W. H. (2006). Proteomic biomarkers for autoimmune disease. PROTEOMICS, 6(14), 4100–4105. -
SYNTHESIS OF VIRAL-SPECIFIC RIBONUCLEIC ACID IN RUBELLA VIRUS-INFECTED CELLS
Wong, K. T., Robinson, W. S., & Merigan, T. C. (1969). SYNTHESIS OF VIRAL-SPECIFIC RIBONUCLEIC ACID IN RUBELLA VIRUS-INFECTED CELLS. JOURNAL OF VIROLOGY, 4(6), 901-? -
Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines
Hueber, W., Tomooka, B. H., Zhao, X., Kidd, B. A., Drijfhout, J. W., Fries, J. F., … Robinson, W. H. (2007). Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines. ANNALS OF THE RHEUMATIC DISEASES, 66(6), 712–19. -
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
Paniagua, R. T., Sharpe, O., Ho, P. P., Chan, S. M., Chang, A., Higgins, J. P., … Robinson, W. H. (2006). Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis. JOURNAL OF CLINICAL INVESTIGATION, 116(10), 2633–42. -
Tolerizing DNA vaccines for autoimmune arthritis
Ho, P. P., Higgins, J. P., Kidd, B. A., Tomooka, B., Digennaro, C., Lee, L. Y., … Robinson, W. H. (2006). Tolerizing DNA vaccines for autoimmune arthritis. AUTOIMMUNITY, 39(8), 675–82. -
Imatinib for the treatment of rheumatic diseases
Paniagua, R. T., & Robinson, W. H. (2007). Imatinib for the treatment of rheumatic diseases. NATURE CLINICAL PRACTICE RHEUMATOLOGY, 3(4), 190–91. -
Identification of biomarkers associated with the development of hepatocellular carcinoma in CuZn superoxide dismutase deficient mice
Elchuri, S., Naeemuddin, M., Sharpe, O., Robinson, W. H., & Huang, T.-T. (2007). Identification of biomarkers associated with the development of hepatocellular carcinoma in CuZn superoxide dismutase deficient mice. PROTEOMICS, 7(12), 2121–29. -
Protective and therapeutic role for alpha B-crystallin in autoimmune demyelination
Ousman, S. S., Tomooka, B. H., Van Noort, J. M., Wawrousek, E. F., O'Connor, K. C., Hafler, D. A., … Steinman, L. (2007). Protective and therapeutic role for alpha B-crystallin in autoimmune demyelination. NATURE, 448(7152), 474–U7. -
Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial
Bar-Or, A., Vollmer, T., Antel, J., Arnold, D. L., Bodner, C. A., Campagnolo, D., … Garren, H. (2007). Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial. ARCHIVES OF NEUROLOGY, 64(10), 1407–15. -
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
Han, M. H., Hwang, S.-I., Roy, D. B., Lundgren, D. H., Price, J. V., Ousman, S. S., … Steinman, L. (2008). Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. NATURE, 451(7182), 1076–U2. -
Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance
Shachaf, C. M., Gentles, A. J., Elchuri, S., Sahoo, D., Soen, Y., Sharpe, O., … Felsher, D. W. (2008). Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. CANCER RESEARCH, 68(13), 5132–42. -
Regulation of tissue inflammation by thrombi n-activatable carboxypeptidase B (or TAFI)
Leung, L. L. K., Myles, T., Nishimura, T., Song, J. J., & Robinson, W. H. (2008). Regulation of tissue inflammation by thrombi n-activatable carboxypeptidase B (or TAFI). MOLECULAR IMMUNOLOGY, 45(16), 4080–83. -
Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination
Kidd, B. A., Ho, P. P., Sharpe, O., Zhao, X., Tomooka, B. H., Kanter, J. L., … Robinson, W. H. (2008). Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination. ARTHRITIS RESEARCH & THERAPY, 10(5). -
Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements
Li, H., Chen, W., Zhou, Y., Abidi, P., Sharpe, O., Robinson, W. H., … Liu, J. (2009). Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements. JOURNAL OF LIPID RESEARCH, 50(5), 820–831. -
Molecular Framework for Response to Imatinib Mesylate in Systemic Sclerosis
Chung, L., Fiorentino, D. F., Benbarak, M. J., Adler, A. S., Mariano, M. M., Paniagua, R. T., … Robinson, W. H. (2009). Molecular Framework for Response to Imatinib Mesylate in Systemic Sclerosis. ARTHRITIS AND RHEUMATISM, 60(2), 584–91. -
Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis
Hueber, W., Tomooka, B. H., Batliwalla, F., Li, W., Monach, P. A., Tibshirani, R. J., … Robinson, W. H. (2009). Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY, 11(3). -
Tyrosine kinases as targets for the treatment of rheumatoid arthritis
Swanson, C. D. A., Paniagua, R. T., Lindstrom, T. M., & Robinson, W. H. (2009). Tyrosine kinases as targets for the treatment of rheumatoid arthritis. NATURE REVIEWS RHEUMATOLOGY, 5(6), 317–24. -
Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease
Britschgi, M., Olin, C. E., Johns, H. T., Takeda-Uchimura, Y., LeMieux, M. C., Rufibach, K., … Wyss-Coray, T. (2009). Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(29), 12145–50. -
Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin
Coffey, G. P., Rajapaksa, R., Liu, R., Sharpe, O., Kuo, C.-C., Krauss, S. W., … Levy, S. (2009). Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin. JOURNAL OF CELL SCIENCE, 122(17), 3137–44. -
A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis
Monach, P. A., Hueber, W., Kessler, B., Tomooka, B. H., BenBarak, M., Simmons, B. P., … Benoist, C. (2009). A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(37), 15867–72. -
Thrombin-Activatable Carboxypeptidase B Cleavage of Osteopontin Regulates Neutrophil Survival and Synoviocyte Binding in Rheumatoid Arthritis
Sharif, S. A., Du, X., Myles, T., Song, J. J., Price, E., Lee, D. M., … Leung, L. L. K. (2009). Thrombin-Activatable Carboxypeptidase B Cleavage of Osteopontin Regulates Neutrophil Survival and Synoviocyte Binding in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 60(10), 2902–12. -
Autoimmunity against Fibrinogen Mediates Inflammatory Arthritis in Mice
Ho, P. P., Lee, L. Y., Zhao, X., Tomooka, B. H., Paniagua, R. T., Sharpe, O., … Robinson, W. H. (2010). Autoimmunity against Fibrinogen Mediates Inflammatory Arthritis in Mice. JOURNAL OF IMMUNOLOGY, 184(1), 379–90. -
Autoimmune Disease Classification by Inverse Association with SNP Alleles
Sirota, M., Schaub, M. A., Batzoglou, S., Robinson, W. H., & Butte, A. J. (2009). Autoimmune Disease Classification by Inverse Association with SNP Alleles. PLOS GENETICS, 5(12). -
c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis
Paniagua, R. T., Chang, A., Mariano, M. M., Stein, E. A., Wang, Q., Lindstrom, T. M., … Robinson, W. H. (2010). c-Fms-mediated differentiation and priming of monocyte lineage cells play a central role in autoimmune arthritis. ARTHRITIS RESEARCH & THERAPY, 12(1). -
A Multitude of Kinases-Which are the Best Targets in Treating Rheumatoid Arthritis?
Lindstrom, T. M., & Robinson, W. H. (2010). A Multitude of Kinases-Which are the Best Targets in Treating Rheumatoid Arthritis? RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 36(2), 367-? -
Biomarkers for rheumatoid arthritis: making it personal.
Lindstrom, T. M., & Robinson, W. H. (2010). Biomarkers for rheumatoid arthritis: making it personal. Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum, 242, 79–84. -
Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury
Vargas, M. E., Watanabe, J., Singh, S. J., Robinson, W. H., & Barres, B. A. (2010). Endogenous antibodies promote rapid myelin clearance and effective axon regeneration after nerve injury. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(26), 11993–98. -
Tyrosine kinases in inflammatory dermatologic disease
Paniagua, R. T., Fiorentino, D. F., Chung, L., & Robinson, W. H. (2011). Tyrosine kinases in inflammatory dermatologic disease. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 65(2), 389–403. -
Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis
Soederstroem, K., Stein, E., Colmenero, P., Purath, U., Mueller-Ladner, U., de Matos, C. T., … Engleman, E. G. (2010). Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(29), 13028–33. -
Rheumatoid Arthritis: A Role for Immunosenescence?
Lindstrom, T. M., & Robinson, W. H. (2010). Rheumatoid Arthritis: A Role for Immunosenescence? JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 58(8), 1565–75. -
Immune Complexes Containing Citrullinated Fibrinogen Costimulate Macrophages via Toll-like Receptor 4 and Fc gamma Receptor
Sokolove, J., Zhao, X., Chandra, P. E., & Robinson, W. H. (2011). Immune Complexes Containing Citrullinated Fibrinogen Costimulate Macrophages via Toll-like Receptor 4 and Fc gamma Receptor. ARTHRITIS AND RHEUMATISM, 63(1), 53–62. -
A model for harmonizing flow cytometry in clinical trials.
Maecker, H. T., McCoy, J. P., Amos, M., Elliott, J., Gaigalas, A., Wang, L., … Yeh, J.-H. (2010). A model for harmonizing flow cytometry in clinical trials. Nature Immunology, 11(11), 975–78. -
Fishing for Biomarkers with Antigen Mimics
Lindstrom, T. M., & Robinson, W. H. (2011). Fishing for Biomarkers with Antigen Mimics. CELL, 144(1), 13–15. -
Chaperone Activity of alpha B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis
Rothbard, J. B., Zhao, X., Sharpe, O., Strohman, M. J., Kurnellas, M., Mellins, E. D., … Steinman, L. (2011). Chaperone Activity of alpha B-Crystallin Is Responsible for Its Incorrect Assignment as an Autoantigen in Multiple Sclerosis. JOURNAL OF IMMUNOLOGY, 186(7), 4263–68. -
Role of the Toll-like receptor pathway in the recognition of orthopedic implant wear-debris particles
Pearl, J. I., Ma, T., Irani, A. R., Huang, Z., Robinson, W. H., Smith, R. L., & Goodman, S. B. (2011). Role of the Toll-like receptor pathway in the recognition of orthopedic implant wear-debris particles. BIOMATERIALS, 32(24), 5535–42. -
Human peptidome display
Robinson, W. H., & Steinman, L. (2011). Human peptidome display. NATURE BIOTECHNOLOGY, 29(6), 500–502. -
Novel multiplex technology for diagnostic characterization of rheumatoid arthritis
Chandra, P. E., Sokolove, J., Hipp, B. G., Lindstrom, T. M., Elder, J. T., Reveille, J. D., … Robinson, W. H. (2011). Novel multiplex technology for diagnostic characterization of rheumatoid arthritis. ARTHRITIS RESEARCH & THERAPY, 13(3). -
Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis
Song, J. J., Hwang, I. Y., Cho, K. H., Garcia, M. A., Kim, A. J., Wang, T. H., … Robinson, W. H. (2011). Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis. JOURNAL OF CLINICAL INVESTIGATION, 121(9), 3517–27. -
Tyrosine Kinase Inhibitors Ameliorate Autoimmune Encephalomyelitis in a Mouse Model of Multiple Sclerosis
Crespo, O., Kang, S. C., Daneman, R., Lindstrom, T. M., Ho, P. P., Sobel, R. A., … Robinson, W. H. (2011). Tyrosine Kinase Inhibitors Ameliorate Autoimmune Encephalomyelitis in a Mouse Model of Multiple Sclerosis. JOURNAL OF CLINICAL IMMUNOLOGY, 31(6), 1010–20. -
Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma
Zhao, L., Yamaguchi, Y., Sharif, S., Du, X.-Y., Song, J. J., Lee, D. M., … Leung, L. L. K. (2011). Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(45), 39520–27. -
Identification of a central role for complement in osteoarthritis
Wang, Q., Rozelle, A. L., Lepus, C. M., Scanzello, C. R., Song, J. J., Larsen, D. M., … Robinson, W. H. (2011). Identification of a central role for complement in osteoarthritis. NATURE MEDICINE, 17(12), 1674–U196. -
Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis
Lin, J. T., Stein, E. A., Wong, M. T., Kalpathy, K. J., Su, L. L., Utz, P. J., … Fathnnan, C. G. (2012). Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis. CLINICAL IMMUNOLOGY, 142(2), 127–38. -
Development and deployment of antigen arrays for investigation of B-cell fine specificity in autoimmune disease.
Sokolove, J., Lindstrom, T. M., & Robinson, W. H. (2012). Development and deployment of antigen arrays for investigation of B-cell fine specificity in autoimmune disease. Frontiers in Bioscience (Elite Edition), 4, 320–330. -
Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
Sohn, D. H., Sokolove, J., Sharpe, O., Erhart, J. C., Chandra, P. E., Lahey, L. J., … Robinson, W. H. (2012). Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4. ARTHRITIS RESEARCH & THERAPY, 14(1). -
Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis
Hwang, S.-J., Choi, B., Kang, S.-S., Chang, J.-H., Kim, Y.-G., Chung, Y.-H., … Chang, E.-J. (2012). Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis. ARTHRITIS RESEARCH & THERAPY, 14(1). -
Therapeutic Effects of Systemic Administration of Chaperone alpha B-Crystallin Associated with Binding Proinflammatory Plasma Proteins
Rothbard, J. B., Kurnellas, M. P., Brownell, S., Adams, C. M., Su, L., Axtell, R. C., … Steinman, L. (2012). Therapeutic Effects of Systemic Administration of Chaperone alpha B-Crystallin Associated with Binding Proinflammatory Plasma Proteins. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(13), 9708–21. -
Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase Ameliorates Collagen-Induced Arthritis
Swanson, C. D., Akama-Garren, E. H., Stein, E. A., Petralia, J. D., Ruiz, P. J., Edalati, A., … Robinson, W. H. (2012). Inhibition of Epidermal Growth Factor Receptor Tyrosine Kinase Ameliorates Collagen-Induced Arthritis. JOURNAL OF IMMUNOLOGY, 188(7), 3513–21. -
New tools for classification and monitoring of autoimmune diseases
Maecker, H. T., Lindstrom, T. M., Robinson, W. H., Utz, P. J., Hale, M., Boyd, S. D., … Fathman, C. G. (2012). New tools for classification and monitoring of autoimmune diseases. NATURE REVIEWS RHEUMATOLOGY, 8(6), 317–28. -
Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis
Sokolove, J., Bromberg, R., Deane, K. D., Lahey, L. J., Derber, L. A., Chandra, P. E., … Robinson, W. H. (2012). Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis. PLOS ONE, 7(5). -
Identification of Naturally Occurring Fatty Acids of the Myelin Sheath That Resolve Neuroinflammation
Ho, P. P., Kanter, J. L., Johnson, A. M., Srinagesh, H. K., Chang, E.-J., Purdy, T. M., … Robinson, W. H. (2012). Identification of Naturally Occurring Fatty Acids of the Myelin Sheath That Resolve Neuroinflammation. SCIENCE TRANSLATIONAL MEDICINE, 4(137). -
Response to 'Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4' - authors' reply.
Sohn, D. H., Sokolove, J., Sharpe, O., Erhart, J. C., Chandra, P. E., Lahey, L. J., … Robinson, W. H. (2012). Response to 'Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4' - authors' reply. Arthritis Research & Therapy, 14(5), 406. -
Genomics and proteomics: Applications in autoimmune diseases.
Hueber, W., & Robinson, W. H. (2009). Genomics and proteomics: Applications in autoimmune diseases. Pharmacogenomics and Personalized Medicine, 2, 39–48. -
Brief report: citrullination within the atherosclerotic plaque: a potential target for the anti-citrullinated protein antibody response in rheumatoid arthritis.
Sokolove, J., Brennan, M. J., Sharpe, O., Lahey, L. J., Kao, A. H., Krishnan, E., … Robinson, W. H. (2013). Brief report: citrullination within the atherosclerotic plaque: a potential target for the anti-citrullinated protein antibody response in rheumatoid arthritis. Arthritis and Rheumatism, 65(7), 1719–24. -
Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing- remitting multiple sclerosis.
Van Haren, K., Tomooka, B. H., Kidd, B. A., Banwell, B., Bar-Or, A., Chitnis, T., … Robinson, W. H. (2013). Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing- remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 19(13), 1726–33. -
HUMAN CD6 POSSESSES A LARGE, ALTERNATIVELY SPLICED CYTOPLASMIC DOMAIN
Robinson, W. H., DEVEGVAR, H. E. N., Prohaska, S. S., Rhee, J. W., & Parnes, J. R. (1995). HUMAN CD6 POSSESSES A LARGE, ALTERNATIVELY SPLICED CYTOPLASMIC DOMAIN. EUROPEAN JOURNAL OF IMMUNOLOGY, 25(10), 2765–69. -
IDENTIFICATION OF A MOUSE PROTEIN HOMOLOGOUS TO THE HUMAN CD6 T-CELL SURFACE PROTEIN AND SEQUENCE OF THE CORRESPONDING CDNA
Robinson, W. H., Prohaska, S. S., Santoro, J. C., Robinson, H. L., & Parnes, J. R. (1995). IDENTIFICATION OF A MOUSE PROTEIN HOMOLOGOUS TO THE HUMAN CD6 T-CELL SURFACE PROTEIN AND SEQUENCE OF THE CORRESPONDING CDNA. JOURNAL OF IMMUNOLOGY, 155(10), 4739–48. -
STRUCTURE OF THE MOUSE CD72 (LYB-2) GENE AND ITS ALTERNATIVELY SPLICED TRANSCRIPTS
Ying, H., Nakayama, E., Robinson, W. H., & Parnes, J. R. (1995). STRUCTURE OF THE MOUSE CD72 (LYB-2) GENE AND ITS ALTERNATIVELY SPLICED TRANSCRIPTS. JOURNAL OF IMMUNOLOGY, 154(6), 2743–52. -
BIOCHEMICAL IDENTITY OF THE MOUSE LY-19.2 AND LY-32.2 ALLOANTIGENS WITH THE B-CELL DIFFERENTIATION ANTIGEN LYB-2/CD72
Robinson, W. H., LANDOLFI, M. M. T., Schafer, H., & Parnes, J. R. (1993). BIOCHEMICAL IDENTITY OF THE MOUSE LY-19.2 AND LY-32.2 ALLOANTIGENS WITH THE B-CELL DIFFERENTIATION ANTIGEN LYB-2/CD72. JOURNAL OF IMMUNOLOGY, 151(9), 4764–72. -
Allele-specific expression of the mouse B-cell surface protein CD72 on T cells
Robinson, W. H., LANDOLFI, M. M. T., & Parnes, J. R. (1997). Allele-specific expression of the mouse B-cell surface protein CD72 on T cells. IMMUNOGENETICS, 45(3), 195–200. -
Porphyromonas Gingivalis (P. gingivalis) is Associated with the Presence of Disease-Specific Autoantibodies in Individuals At Increased Risk for the Future Development of Rheumatoid Arthritis
Mikuls, T. R., Deane, K. D., Payne, J., Thiele, G. M., O'Dell, J. R., Derber, L. A., … Norris, J. M. (2011). Porphyromonas Gingivalis (P. gingivalis) is Associated with the Presence of Disease-Specific Autoantibodies in Individuals At Increased Risk for the Future Development of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 63(10), S300–S300. -
Porphyromonas gingivalis and Disease-Related Autoantibodies in Individuals at Increased Risk of Rheumatoid Arthritis
Mikuls, T. R., Thiele, G. M., Deane, K. D., Payne, J. B., O'Dell, J. R., Yu, F., … Norris, J. M. (2012). Porphyromonas gingivalis and Disease-Related Autoantibodies in Individuals at Increased Risk of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(11), 3522–30. -
Response to 'Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4' - authors' reply
Sohn, D. H., Sokolove, J., Sharpe, O., Erhart, J. C., Chandra, P. E., Lahey, L. J., … Robinson, W. H. (2012). Response to 'Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4' - authors' reply. ARTHRITIS RESEARCH & THERAPY, 14(5). -
Evolution of Preclinical Autoimmunity in Individuals At Risk for Development of Rheumatoid Arthritis
El-Gabalawy, H. S., Robinson, D. B., Smolik, I., Hart, D. M., Ferucci, E. D., Newkirk, M. M., … Robinson, W. H. (2012). Evolution of Preclinical Autoimmunity in Individuals At Risk for Development of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(10), S722–S722. -
Differentially Cleaved Forms of Osteopontin by Thrombin and Carboxypeptidase B (TAF1a) Regulates Neutrophil Viability and Synoviocyte Binding in Rheumatoid Arthritis
Sharif, S., Du, X.-Y., Myles, T., Song, J. J., Price, E. A., Lee, D., … Leung, L. L. (2008). Differentially Cleaved Forms of Osteopontin by Thrombin and Carboxypeptidase B (TAF1a) Regulates Neutrophil Viability and Synoviocyte Binding in Rheumatoid Arthritis. BLOOD. SAN FRANCISCO,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA: AMER SOC HEMATOLOGY. -
Targeting mTOR and MAPK Pathways to Inhibit Naive and Experienced Effector CD4 T Cells in Autoimmunity
Lin, J., Stein, E., Wong, M., Kalpathy, K., Su, L., Utz, P., … Fathman, C. (2010). Targeting mTOR and MAPK Pathways to Inhibit Naive and Experienced Effector CD4 T Cells in Autoimmunity. Presented at the 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, BOSTON,MA,MA,MA,MA,MA: ACADEMIC PRESS INC ELSEVIER SCIENCE. -
The Associations of HLA-DR Shared Epitope Alleles and Serum Cytokines Among Postmenopausal Women with Rheumatoid Factor and Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis.
Talabi, M. B., Mackey, R., Moreland, L. W., Dorman, J., Deane, K. D., Sokolove, J., … Kuller, L. (2012). The Associations of HLA-DR Shared Epitope Alleles and Serum Cytokines Among Postmenopausal Women with Rheumatoid Factor and Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(10), S895–S895. -
Anti-Citrullinated Peptide Autoantibodies to Rheumatoid Synovium Epitopes in Women and Risk of Future Rheumatoid Arthritis.
Arkema, E. V., Goldstein, B. L., Robinson, W. H., Cramb, C., Sokolove, J., Cui, J., … Costenbader, K. H. (2012). Anti-Citrullinated Peptide Autoantibodies to Rheumatoid Synovium Epitopes in Women and Risk of Future Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(10), S685–S686. -
A central anti-inflammatory role of carboxypeptidase B in autoimmune arthritis
Song, J. J., Nishimura, T., Garcia, M., Myles, T., Du, X., Sharif, S., … Robinson, W. (2008). A central anti-inflammatory role of carboxypeptidase B in autoimmune arthritis. ARTHRITIS AND RHEUMATISM. SAN FRANCISCO,CA,CA,CA,CA,CA: WILEY-BLACKWELL. -
Rheumatoid arthritis (RA)-related antibody positivity is associated with serum cytokine elevations in RA-free first-degree relatives (FDRs) of RA-probands
Deane, K. D., Robinson, W. H., Majka, D. S., Parrish, L. A., BenBarak, M., Weisman, M. H., … Holers, V. M. (2008). Rheumatoid arthritis (RA)-related antibody positivity is associated with serum cytokine elevations in RA-free first-degree relatives (FDRs) of RA-probands. ARTHRITIS AND RHEUMATISM, 58(9), S615–S615. -
Anti-GITR treatment in collagen-induced arthritis results in enhanced epitope spreading and increased antibodies to citrullinated protein antigens (ACPA)
Cozine, C., Robinson, W. H., BenBarak, M., & Holers, V. M. (2008). Anti-GITR treatment in collagen-induced arthritis results in enhanced epitope spreading and increased antibodies to citrullinated protein antigens (ACPA). ARTHRITIS AND RHEUMATISM, 58(9), S405–S406. -
Molecular framework for response to imatinib mesylate in systemic sclerosis
Chung, L., Fiorentino, D. F., Benbarak, M. J., Adler, A. S., Mariano, M. M., Paniagua, R. T., … Robinson, W. H. (2008). Molecular framework for response to imatinib mesylate in systemic sclerosis. ARTHRITIS AND RHEUMATISM. SAN FRANCISCO,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA: WILEY-BLACKWELL. -
Development of peptide microarrays to investigate autoantibody epitope specificity in Pemphigus vulgaris
Hazelton, J., Patel, M., Furstenberg, G., Tyagi, S., Haab, B. B., Robinson, W. H., … Sinha, A. A. (2011). Development of peptide microarrays to investigate autoantibody epitope specificity in Pemphigus vulgaris. Presented at the 71st Annual Meeting of the Society-for-Investigative-Dermatology, PHOENIX,AZ,AZ,AZ,AZ,AZ: NATURE PUBLISHING GROUP. -
Development of protein microarrays to investigate autoantibody profiles in pemphigus vulgaris
Patel, M., Furstenberg, G., Hazelton, J., Tiagi, S., Seiffert-Sinha, K., Haab, B. B., … Sinha, A. A. (2010). Development of protein microarrays to investigate autoantibody profiles in pemphigus vulgaris. Presented at the Annual Meeting of the Society-for-Investigative-Dermatology, ATLANTA,GA,GA,GA,GA,GA: NATURE PUBLISHING GROUP. -
Evaluation of an imatinib response gene signature in patients with systemic sclerosis
Chung, L., Ruiz, P., Wood, T., Shoor, S., Robinson, W., Whitfield, M., … Fiorentino, D. (2010). Evaluation of an imatinib response gene signature in patients with systemic sclerosis. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. CLINICAL & EXPER RHEUMATOLOGY. -
Complement receptor CR2/CR1 deficiency protects mice from collagen-induced arthritis and associates with reduced autoantibodies to type II collagen and citrullinated antigens
Kuhn, K. A., Cozine, C. L., Tomooka, B., Robinson, W. H., & Holers, V. M. (2008). Complement receptor CR2/CR1 deficiency protects mice from collagen-induced arthritis and associates with reduced autoantibodies to type II collagen and citrullinated antigens. MOLECULAR IMMUNOLOGY, 45(10), 2808–19. -
The Number of Elevated Cytokines and Chemokines in Preclinical Seropositive Rheumatoid Arthritis Predicts Time to Diagnosis in an Age-Dependent Manner
Deane, K. D., O'Donnell, C. I., Hueber, W., Majka, D. S., Lazar, A. A., Derber, L. A., … Holers, V. M. (2010). The Number of Elevated Cytokines and Chemokines in Preclinical Seropositive Rheumatoid Arthritis Predicts Time to Diagnosis in an Age-Dependent Manner. ARTHRITIS AND RHEUMATISM, 62(11), 3161–72. -
Correlation between Circulating Plasmablasts and Disease Activity in Patients with ACPA plus Rheumatoid Arthritis
Tan, Y. C., Sokolove, J., & Robinson, W. (2010). Correlation between Circulating Plasmablasts and Disease Activity in Patients with ACPA plus Rheumatoid Arthritis. Presented at the 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, BOSTON,MA,MA,MA,MA: ACADEMIC PRESS INC ELSEVIER SCIENCE. -
Tyrosine Kinases in Autoimmune Demyelination
Crespo, O., Kang, S., Daneman, R., Sobel, R., Ho, P., Steinman, L., & Robinson, W. (2009). Tyrosine Kinases in Autoimmune Demyelination. Presented at the 9th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, SAN FRANCISCO,CA,CA,CA,CA: ACADEMIC PRESS INC ELSEVIER SCIENCE. -
The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
Chang, B. Y., Huang, M. M., Francesco, M., Chen, J., Sokolove, J., Magadala, P., … Buggy, J. J. (2011). The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells. ARTHRITIS RESEARCH & THERAPY, 13(4). -
The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes
Cloutier, N., Tan, S., Boudreau, L. H., Cramb, C., Subbaiah, R., Lahey, L., … Boilard, E. (2013). The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. EMBO MOLECULAR MEDICINE, 5(2), 235–49. -
Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems
Tang, H., Lee, M., Sharpe, O., Salamone, L., Noonan, E. J., Hoang, C. D., … Shrager, J. B. (2012). Oxidative stress-responsive microRNA-320 regulates glycolysis in diverse biological systems. FASEB JOURNAL, 26(11), 4710–21. -
Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes.
Roep, B. O., Solvason, N., Gottlieb, P. A., Abreu, J. R. F., Harrison, L. C., Eisenbarth, G. S., … Steinman, L. (2013). Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8+ T Cells in Type 1 Diabetes. Science Translational Medicine, 5(191), 191ra82-? -
Elemental bio-imaging of calcium phosphate crystal deposits in knee samples from arthritic patients
Austin, C., Hare, D., Rozelle, A. L., Robinson, W. H., Grimm, R., & Doble, P. (2009). Elemental bio-imaging of calcium phosphate crystal deposits in knee samples from arthritic patients. METALLOMICS, 1(2), 142–47. -
Identification of acute phase reactants and cytokines useful for monitoring infliximab therapy in ankylosing spondylitis
Romero-Sanchez, C., Robinson, W. H., Tomooka, B. H., Londono, J., Valle-Onate, R., Huang, F., … Yu, D. T. Y. (2008). Identification of acute phase reactants and cytokines useful for monitoring infliximab therapy in ankylosing spondylitis. CLINICAL RHEUMATOLOGY, 27(11), 1429–35. -
B Cells and Transplantation: An Educational Resource
Small, T. N., Robinson, W. H., & Miklos, D. B. (2009). B Cells and Transplantation: An Educational Resource. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 15(1), 104–13. -
Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis
Zhao, X., Qureshi, F., Eastman, P. S., Manning, W. C., Alexander, C., Robinson, W. H., & Hesterberg, L. K. (2012). Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. JOURNAL OF IMMUNOLOGICAL METHODS, 378(1-2), 72–80. -
Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis.
Lepus, C. M., Song, J. J., Wang, Q., Wagner, C. A., Lindstrom, T. M., Chu, C. R., … Robinson, W. H. (2014). Brief report: carboxypeptidase B serves as a protective mediator in osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.), 66(1), 101–6. -
Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus
Price, J. V., Haddon, D. J., Kemmer, D., Delepine, G., Mandelbaum, G., Jarrell, J. A., … Utz, P. J. (2013). Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus. JOURNAL OF CLINICAL INVESTIGATION, 123(12), 5135–45. -
Clinical optimization of antigen specific modulation of type 1 diabetes with the plasmid DNA platform
Gottlieb, P., Utz, P. J., Robinson, W., & Steinman, L. (2013). Clinical optimization of antigen specific modulation of type 1 diabetes with the plasmid DNA platform. CLINICAL IMMUNOLOGY, 149(3), 297–306. -
High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination.
Tan, Y.-C., Blum, L. K., Kongpachith, S., Ju, C.-H., Cai, X., Lindstrom, T. M., … Robinson, W. H. (2014). High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination. Clinical Immunology , 151(1), 55–65. -
Serum inflammatory mediators as markers of human lyme disease activity.
Soloski, M. J., Crowder, L. A., Lahey, L. J., Wagner, C. A., Robinson, W. H., & Aucott, J. N. (2014). Serum inflammatory mediators as markers of human lyme disease activity. PloS One, 9(4). -
Identifying functional anti-Staphylococcus aureus antibodies by sequencing antibody repertoires of patient plasmablasts
Lu, D. R., Tan, Y.-C., Kongpachith, S., Cai, X., Stein, E. A., Lindstrom, T. M., … Robinson, W. H. (2014). Identifying functional anti-Staphylococcus aureus antibodies by sequencing antibody repertoires of patient plasmablasts. CLINICAL IMMUNOLOGY, 152(1-2), 77–89. -
Relatives Without Rheumatoid Arthritis Show Reactivity to Anti-Citrullinated Protein/Peptide Antibodies That Are Associated With Arthritis-Related Traits: Studies of the Etiology of Rheumatoid Arthritis
Young, K. A., Deane, K. D., Derber, L. A., Hughes-Austin, J. M., Wagner, C. A., Sokolove, J., … Norris, J. M. (2013). Relatives Without Rheumatoid Arthritis Show Reactivity to Anti-Citrullinated Protein/Peptide Antibodies That Are Associated With Arthritis-Related Traits: Studies of the Etiology of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65(8), 1995–2004. -
Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA)
Hughes-Austin, J. M., Deane, K. D., Derber, L. A., Kolfenbach, J. R., Zerbe, G. O., Sokolove, J., … Norris, J. M. (2013). Multiple cytokines and chemokines are associated with rheumatoid arthritis-related autoimmunity in first-degree relatives without rheumatoid arthritis: Studies of the Aetiology of Rheumatoid Arthritis (SERA). ANNALS OF THE RHEUMATIC DISEASES, 72(6), 901–7. -
Optical imaging of articular cartilage degeneration using near-infrared dipicolylamine probes.
Hu, X., Wang, Q., Liu, Y., Liu, H., Qin, C., Cheng, K., … Cheng, Z. (2014). Optical imaging of articular cartilage degeneration using near-infrared dipicolylamine probes. Biomaterials, 35(26), 7511–21. -
Rheumatoid Factor as a Potentiator of Anti-Citrullinated Protein Antibody-Mediated Inflammation in Rheumatoid Arthritis
Sokolove, J., Johnson, D. S., Lahey, L. J., Wagner, C. A., Cheng, D., Thiele, G. M., … Robinson, W. H. (2014). Rheumatoid Factor as a Potentiator of Anti-Citrullinated Protein Antibody-Mediated Inflammation in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66(4), 813–21. -
Carboxypeptidase B Serves as a Protective Mediator in Osteoarthritis
Lepus, C. M., Song, J. J., Wang, Q., Wagner, C. A., Lindstrom, T. M., Chu, C. R., … Robinson, W. H. (2014). Carboxypeptidase B Serves as a Protective Mediator in Osteoarthritis. ARTHRITIS & RHEUMATOLOGY, 66(1), 101–6. -
Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis
Mikuls, T. R., Payne, J. B., Yu, F., Thiele, G. M., Reynolds, R. J., Cannon, G. W., … O'Dell, J. R. (2014). Periodontitis and Porphyromonas gingivalis in Patients With Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66(5), 1090–1100. -
Peptidylarginine Deiminase 4 Contributes to Tumor Necrosis Factor alpha-Induced Inflammatory Arthritis
Shelef, M. A., Sokolove, J., Lahey, L. J., Wagner, C. A., Sackmann, E. K., Warner, T. F., … Huttenlocher, A. (2014). Peptidylarginine Deiminase 4 Contributes to Tumor Necrosis Factor alpha-Induced Inflammatory Arthritis. ARTHRITIS & RHEUMATOLOGY, 66(6), 1482–91. -
Street-experienced peripheral B cells traffic to the brain.
Lu, D. R., & Robinson, W. H. (2014). Street-experienced peripheral B cells traffic to the brain. Science Translational Medicine, 6(248), 248fs31-? -
Role of Protein Phosphatase Magnesium-Dependent 1A and Anti-Protein Phosphatase Magnesium-Dependent 1A Autoantibodies in Ankylosing Spondylitis
Kim, Y.-G., Sohn, D. H., Zhao, X., Sokolove, J., Lindstrom, T. M., Yoo, B., … Robinson, W. H. (2014). Role of Protein Phosphatase Magnesium-Dependent 1A and Anti-Protein Phosphatase Magnesium-Dependent 1A Autoantibodies in Ankylosing Spondylitis. ARTHRITIS & RHEUMATOLOGY, 66(10), 2793–2803. -
Contribution of Mast Cell-Derived Interleukin-1 beta to Uric Acid Crystal-Induced Acute Arthritis in Mice
Reber, L. L., Marichal, T., Sokolove, J., Starkl, P., Gaudenzio, N., Iwakura, Y., … Galli, S. J. (2014). Contribution of Mast Cell-Derived Interleukin-1 beta to Uric Acid Crystal-Induced Acute Arthritis in Mice. ARTHRITIS & RHEUMATOLOGY, 66(10), 2881–91. -
Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis
Tan, Y.-C., Kongpachith, S., Blum, L. K., Ju, C.-H., Lahey, L. J., Lu, D. R., … Robinson, W. H. (2014). Barcode-Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66(10), 2706–15. -
Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles.
Wagner, C. A., Sokolove, J., Lahey, L. J., Bengtsson, C., Saevarsdottir, S., Alfredsson, L., … Robinson, W. H. (2015). Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 'shared epitope' alleles. Annals of the Rheumatic Diseases, 74(3), 579–86. -
Malondialdehyde-Acetaldehyde Adducts and Anti-Malondialdehyde-Acetaldehyde Antibodies in Rheumatoid Arthritis
Thiele, G. M., Duryee, M. J., Anderson, D. R., Klassen, L. W., Mohring, S. M., Young, K. A., … Mikuls, T. R. (2015). Malondialdehyde-Acetaldehyde Adducts and Anti-Malondialdehyde-Acetaldehyde Antibodies in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 67(3), 645–55. -
Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: An observational cohort study
Davis, M. L. R., LeVan, T. D., Yu, F., Sayles, H., Sokolove, J., Robinson, W., … Mikuls, T. R. (2015). Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: An observational cohort study. INTERNATIONAL IMMUNOPHARMACOLOGY, 24(2), 346–52. -
Biomarkers for rheumatoid arthritis: Making it personal
Lindstrom, T. M., & Robinson, W. H. (2010). Biomarkers for rheumatoid arthritis: Making it personal. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 70, 79–84. -
Quantitative Radiologic Imaging Techniques for Articular Cartilage Composition: Toward Early Diagnosis and Development of Disease-Modifying Therapeutics for Osteoarthritis
Oei, E. H. G., van Tiel, J., Robinson, W. H., & Gold, G. E. (2014). Quantitative Radiologic Imaging Techniques for Articular Cartilage Composition: Toward Early Diagnosis and Development of Disease-Modifying Therapeutics for Osteoarthritis. ARTHRITIS CARE & RESEARCH, 66(8), 1129–41. -
Predictive Value of Autoantibody Testing for Validating Self-reported Diagnoses of Rheumatoid Arthritis in the Women's Health Initiative
Walitt, B., Mackey, R., Kuller, L., Deane, K. D., Robinson, W., Holers, V. M., … Moreland, L. (2013). Predictive Value of Autoantibody Testing for Validating Self-reported Diagnoses of Rheumatoid Arthritis in the Women's Health Initiative. AMERICAN JOURNAL OF EPIDEMIOLOGY, 177(9), 887–93. -
Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case-control study
Arkema, E. V., Goldstein, B. L., Robinson, W., Sokolove, J., Wagner, C. A., Malspeis, S., … Costenbader, K. H. (2013). Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case-control study. ARTHRITIS RESEARCH & THERAPY, 15(5). -
N-alpha-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-L-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis
Willis, V. C., Gizinski, A. M., Banda, N. K., Causey, C. P., Knuckley, B., Cordova, K. N., … Holers, V. M. (2011). N-alpha-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-L-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis. JOURNAL OF IMMUNOLOGY, 186(7), 4396–4404. -
Mechanistic biomarkers for clinical decision making in rheumatic diseases
Robinson, W. H., Lindstrom, T. M., Cheung, R. K., & Sokolove, J. (2013). Mechanistic biomarkers for clinical decision making in rheumatic diseases. NATURE REVIEWS RHEUMATOLOGY, 9(5), 267–76. -
Determinants of Mortality Among Postmenopausal Women in the Women's Health Initiative Who Report Rheumatoid Arthritis
Kuller, L. H., Mackey, R. H., Walitt, B. T., Deane, K. D., Holers, V. M., Robinson, W. H., … Moreland, L. W. (2014). Determinants of Mortality Among Postmenopausal Women in the Women's Health Initiative Who Report Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66(3), 497–507. -
Rheumatoid Arthritis in the Womens Health Initiative: Methods and Baseline Evaluation
Kuller, L. H., Mackey, R. H., Walitt, B. T., Deane, K. D., Holers, V. M., Robinson, W. H., … Moreland, L. W. (2014). Rheumatoid Arthritis in the Womens Health Initiative: Methods and Baseline Evaluation. AMERICAN JOURNAL OF EPIDEMIOLOGY, 179(7), 917–26. -
Reply: To PMID 24497204.
Shelef, M. A., Sokolove, J., Robinson, W. H., & Huttenlocher, A. (2014). Reply: To PMID 24497204. Arthritis & Rheumatology , 66(9), 2644–45. -
Alveolar Bone Loss Is Associated With Circulating Anti-Citrullinated Protein Antibody (ACPA) in Patients With Rheumatoid Arthritis
Gonzalez, S. M., Payne, J. B., Yu, F., Thiele, G. M., Erickson, A. R., Johnson, P. G., … Mikuls, T. R. (2015). Alveolar Bone Loss Is Associated With Circulating Anti-Citrullinated Protein Antibody (ACPA) in Patients With Rheumatoid Arthritis. JOURNAL OF PERIODONTOLOGY, 86(2), 222–31. -
Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma
Gartner, J. J., Parker, S. C. J., Prickett, T. D., Dutton-Regester, K., Stitzel, M. L., Lin, J. C., … Samuels, Y. (2013). Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(33), 13481–13486. -
Sequencing the functional antibody repertoire-diagnostic and therapeutic discovery
Robinson, W. H. (2015). Sequencing the functional antibody repertoire-diagnostic and therapeutic discovery. NATURE REVIEWS RHEUMATOLOGY, 11(3), 171–82. -
Association of fine specificity and repertoire expansion of anticitrullinated peptide antibodies with rheumatoid arthritis associated interstitial lung disease
Giles, J. T., Danoff, S. K., Sokolove, J., Wagner, C. A., Winchester, R., Pappas, D. A., … Bathon, J. M. (2014). Association of fine specificity and repertoire expansion of anticitrullinated peptide antibodies with rheumatoid arthritis associated interstitial lung disease. ANNALS OF THE RHEUMATIC DISEASES, 73(8), 1487–94. -
Optimal approaches to data collection and analysis of potential immune mediated disorders in clinical trials of new vaccines
Da Silva, F. T., De Keyser, F., Lambert, P.-H., Robinson, W. H., Westhovens, R., & Sindic, C. (2013). Optimal approaches to data collection and analysis of potential immune mediated disorders in clinical trials of new vaccines. VACCINE, 31(14), 1870–76. -
Oral and topical boswellic acid attenuates mouse osteoarthritis
Wang, Q., Pan, X., Wong, H. H., Wagner, C. A., Lahey, L. J., Robinson, W. H., & Sokolove, J. (2014). Oral and topical boswellic acid attenuates mouse osteoarthritis. OSTEOARTHRITIS AND CARTILAGE, 22(1), 128–32. -
Mass cytometry analysis shows that a novel memory phenotype B cell is expanded in multiple myeloma.
Hansmann, L., Blum, L., Ju, C.-H., Liedtke, M., Robinson, W. H., & Davis, M. M. (2015). Mass cytometry analysis shows that a novel memory phenotype B cell is expanded in multiple myeloma. Cancer Immunology Research, 3(6), 650–60. -
CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis
Huang, Q.-Q., Perlman, H., Birkett, R., Doyle, R., Fang, D., Haines, G. K., … Pope, R. M. (2015). CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. NATURE COMMUNICATIONS, 6. -
Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative
Mackey, R. H., Kuller, L. H., Deane, K. D., Walitt, B. T., Chang, Y.-F., Holers, V. M., … Moreland, L. W. (2015). Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative. ARTHRITIS & RHEUMATOLOGY, 67(9), 2311–22. -
Mass Cytometry Analysis Shows That a Novel Memory Phenotype B Cell Is Expanded in Multiple Myeloma
Hansmann, L., Blum, L., Ju, C.-H., Liedtke, M., Robinson, W. H., & Davis, M. M. (2015). Mass Cytometry Analysis Shows That a Novel Memory Phenotype B Cell Is Expanded in Multiple Myeloma. CANCER IMMUNOLOGY RESEARCH, 3(6), 650–60. -
Contribution of mast cell-derived interleukin-1ß to uric acid crystal-induced acute arthritis in mice.
Reber, L. L., Marichal, T., Sokolove, J., Starkl, P., Gaudenzio, N., Iwakura, Y., … Galli, S. J. (2014). Contribution of mast cell-derived interleukin-1ß to uric acid crystal-induced acute arthritis in mice. Arthritis & Rheumatology , 66(10), 2881–91. -
Barcode-enabled sequencing of plasmablast antibody repertoires in rheumatoid arthritis.
Tan, Y.-C., Kongpachith, S., Blum, L. K., Ju, C.-H., Lahey, L. J., Lu, D. R., … Robinson, W. H. (2014). Barcode-enabled sequencing of plasmablast antibody repertoires in rheumatoid arthritis. Arthritis & Rheumatology , 66(10), 2706–15. -
Development of a Multiantigen Panel for Improved Detection of Borrelia burgdorferi Infection in Early Lyme Disease
Lahey, L. J., Panas, M. W., Mao, R., Delanoy, M., Flanagan, J. J., Binder, S. R., … Robinson, W. H. (2015). Development of a Multiantigen Panel for Improved Detection of Borrelia burgdorferi Infection in Early Lyme Disease. JOURNAL OF CLINICAL MICROBIOLOGY, 53(12), 3834–41. -
Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice
Toivola, D. M., Habtezion, A., Misiorek, J. O., Zhang, L., Nystrom, J. H., Sharpe, O., … Omary, M. B. (2015). Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice. FASEB JOURNAL, 29(12), 5081–89. -
Local Joint Inflammation and Histone Citrullination in a Murine Model of the Transition From Preclinical Autoimmunity to Inflammatory Arthritis
Sohn, D. H., Rhodes, C., Onuma, K., Zhao, X., Sharpe, O., Gazitt, T., … Sokolove, J. (2015). Local Joint Inflammation and Histone Citrullination in a Murine Model of the Transition From Preclinical Autoimmunity to Inflammatory Arthritis. ARTHRITIS & RHEUMATOLOGY, 67(11), 2877–87. -
A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients
Ligocki, A. J., Rivas, J. R., Rounds, W. H., Guzman, A. A., Li, M., Spadaro, M., … Monson, N. L. (2015). A Distinct Class of Antibodies May Be an Indicator of Gray Matter Autoimmunity in Early and Established Relapsing Remitting Multiple Sclerosis Patients. ASN NEURO, 7(5). -
Multiplexed autoantigen microarrays identify HLA as a key driver of anti-desmoglein and -non-desmoglein reactivities in pemphigus
Sajda, T., Hazelton, J., Patel, M., Seiffert-Sinha, K., Steinman, L., Robinson, W., … Sinha, A. A. (2016). Multiplexed autoantigen microarrays identify HLA as a key driver of anti-desmoglein and -non-desmoglein reactivities in pemphigus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(7), 1859–64. -
The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression
Kragstrup, T. W., Greisen, S. R., Nielsen, M. A., Rhodes, C., Stengaard-Pedersen, K., Hetland, M. L., … Deleuran, B. (2016). The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression. ARTHRITIS RESEARCH & THERAPY, 18. -
Biomarkers to guide clinical therapeutics in rheumatology?
Robinson, W. H., & Mao, R. (2016). Biomarkers to guide clinical therapeutics in rheumatology? CURRENT OPINION IN RHEUMATOLOGY, 28(2), 168–75. -
Vascular calcifications on hand radiographs in rheumatoid arthritis and associations with autoantibodies, cardiovascular risk factors and mortality
Solow, E. B., Yu, F., Thiele, G. M., Sokolove, J., Robinson, W. H., Pruhs, Z. M., … Mikuls, T. R. (2015). Vascular calcifications on hand radiographs in rheumatoid arthritis and associations with autoantibodies, cardiovascular risk factors and mortality. RHEUMATOLOGY, 54(9), 1587–1595. -
Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes
Kim, J.-H., Furrow, E., Ritt, M. G., Utz, P. J., Robinson, W. H., Yu, L., … Modiano, J. F. (2016). Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes. PLOS ONE, 11(3). -
Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model.
Yu, C., Burns, J. C., Robinson, W. H., Utz, P. J., Ho, P. P., Steinman, L., & Frey, A. B. (2016). Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model. Journal of Diabetes Research, 2016, 9083103-? -
Impact of baseline anti-cyclic citrullinated peptide-2 antibody concentration on efficacy outcomes following treatment with subcutaneous abatacept or adalimumab: 2-year results from the AMPLE trial
Sokolove, J., Schiff, M., Fleischmann, R., Weinblatt, M. E., Connolly, S. E., Johnsen, A., … Robinson, W. H. (2016). Impact of baseline anti-cyclic citrullinated peptide-2 antibody concentration on efficacy outcomes following treatment with subcutaneous abatacept or adalimumab: 2-year results from the AMPLE trial. ANNALS OF THE RHEUMATIC DISEASES, 75(4), 709–14. -
Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology
Abrams, G. D., Luria, A., Carr, R. A., Rhodes, C., Robinson, W. H., & Sokolove, J. (2016). Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology. JOURNAL OF SHOULDER AND ELBOW SURGERY, 25(6), 989–97. -
B cell depletion with rituximab in patients with rheumatoid arthritis: Multiplex bead array reveals the kinetics of IgG and IgA antibodies to citrullinated antigens
Cambridge, G., Leandro, M. J., Lahey, L. J., Fairhead, T., Robinson, W. H., & Sokolove, J. (2016). B cell depletion with rituximab in patients with rheumatoid arthritis: Multiplex bead array reveals the kinetics of IgG and IgA antibodies to citrullinated antigens. JOURNAL OF AUTOIMMUNITY, 70, 22–30. -
CCL19 as a Chemokine Risk Factor for Posttreatment Lyme Disease Syndrome: a Prospective Clinical Cohort Study.
Aucott, J. N., Soloski, M. J., Rebman, A. W., Crowder, L. A., Lahey, L. J., Wagner, C. A., … Bechtold, K. T. (2016). CCL19 as a Chemokine Risk Factor for Posttreatment Lyme Disease Syndrome: a Prospective Clinical Cohort Study. Clinical and Vaccine Immunology , 23(9), 757–66. -
Identification of KRT16 as a target of an autoantibody response in complex regional pain syndrome.
Tajerian, M., Hung, V., Khan, H., Lahey, L. J., Sun, Y., Birklein, F., … Clark, J. D. (2016). Identification of KRT16 as a target of an autoantibody response in complex regional pain syndrome. Experimental Neurology, 287, 14–20. -
Associations of Circulating Cytokines and Chemokines With Cancer Mortality in Men With Rheumatoid Arthritis.
England, B. R., Sokolove, J., Robinson, W. H., Thiele, G. M., Ganti, A. K., Sayles, H., … Mikuls, T. R. (2016). Associations of Circulating Cytokines and Chemokines With Cancer Mortality in Men With Rheumatoid Arthritis. Arthritis & Rheumatology , 68(10), 2394–2402. -
Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.
Kinslow, J. D., Blum, L. K., Deane, K. D., Demoruelle, M. K., Okamoto, Y., Parish, M. C., … Holers, V. M. (2016). Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis. Arthritis & Rheumatology , 68(10), 2372–83. -
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis.
Robinson, W. H., Lepus, C. M., Wang, Q., Raghu, H., Mao, R., Lindstrom, T. M., & Sokolove, J. (2016). Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nature Reviews. Rheumatology, 12(10), 580–92. -
Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease
Robinson, W. H., Garren, H., Utz, P. J., & Steinman, L. (2002). Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease. CLINICAL IMMUNOLOGY, 103(1), 7–12. -
A model for harmonizing flow cytometry in clinical trials
Maecker, H. T., & McCoy, J. P. (2010). A model for harmonizing flow cytometry in clinical trials. NATURE IMMUNOLOGY, 11(11), 975–78. -
Citrullination Within the Atherosclerotic Plaque: A Potential Target for the Anti-Citrullinated Protein Antibody Response in Rheumatoid Arthritis
Sokolove, J., Brennan, M. J., Sharpe, O., Lahey, L. J., Kao, A. H., Krishnan, E., … Robinson, W. H. (2013). Citrullination Within the Atherosclerotic Plaque: A Potential Target for the Anti-Citrullinated Protein Antibody Response in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65(7), 1719–24. -
Associations of Circulating Cytokines and Chemokines With Cancer Mortality in Men With Rheumatoid Arthritis
England, B. R., Sokolove, J., Robinson, W. H., Thiele, G. M., Ganti, A. K., Sayles, H., … Mikuls, T. R. (2016). Associations of Circulating Cytokines and Chemokines With Cancer Mortality in Men With Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 68(10), 2394–2402. -
Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis
Kragstrup, T. W., Jalilian, B., Hvid, M., Kjaergaard, A., Ostgard, R., Schiottz-Christensen, B., … Deleuran, B. (2014). Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis. ARTHRITIS RESEARCH & THERAPY, 16(1). -
Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129.
Xiao, C., Zhang, Q., Nguyen-Tân, P. F., List, M., Weber, R. S., Ang, K. K., … Bruner, D. (2016). Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129. International Journal of Radiation Oncology, Biology, Physics. -
Increased pretreatment serum IFN-/ ratio predicts non-response to tumour necrosis factor inhibition in rheumatoid arthritis
Muskardin, T. W., Vashisht, P., Dorschner, J. M., Jensen, M. A., Chrabot, B. S., Kern, M., … Niewold, T. B. (2016). Increased pretreatment serum IFN-/ ratio predicts non-response to tumour necrosis factor inhibition in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES, 75(10), 1757–62. -
Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study
Regules, J. A., Cicatelli, S. B., Bennett, J. W., Paolino, K. M., Twomey, P. S., Moon, J. E., … Vekemans, J. (2016). Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study. JOURNAL OF INFECTIOUS DISEASES, 214(5), 762–71. -
The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression.
Kragstrup, T. W., Greisen, S. R., Nielsen, M. A., Rhodes, C., Stengaard-Pedersen, K., Hetland, M. L., … Deleuran, B. (2015). The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between disease-associated autoantibodies and radiographic progression. Arthritis Research & Therapy, 18, 61-? -
Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells.
Mukherjee, N., Lu, Y., Almeida, A., Lambert, K., Shiau, C.-W., Su, J.-C., … Shellman, Y. G. (2016). Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells. Oncotarget. -
Increased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans.
Sokolove, J., Wagner, C. A., Lahey, L. J., Sayles, H., Duryee, M. J., Reimold, A. M., … Mikuls, T. R. (2016). Increased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans. Rheumatology , -? -
Association of Anti-Citrullinated Peptide Antibodies with Coronary Artery Calcification in Rheumatoid Arthritis.
Geraldino-Pardilla, L., Giles, J. T., Sokolove, J., Zartoshti, A., Robinson, W. H., Budoff, M., … Bathon, J. M. (2016). Association of Anti-Citrullinated Peptide Antibodies with Coronary Artery Calcification in Rheumatoid Arthritis. Arthritis Care & Research. -
Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis.
Kragstrup, T. W., Jalilian, B., Hvid, M., Kjærgaard, A., Østgård, R., Schiøttz-Christensen, B., … Deleuran, B. (2014). Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritis. Arthritis Research & Therapy, 16(1), R42-? -
Identification of KRT16 as a target of an autoantibody response in complex regional pain syndrome
Tajerian, M., Hung, V., Khan, H., Lahey, L. J., Sun, Y., Birklein, F., … Clark, J. D. (2017). Identification of KRT16 as a target of an autoantibody response in complex regional pain syndrome. EXPERIMENTAL NEUROLOGY, 287, 14–20. -
CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis.
Raghu, H., Lepus, C. M., Wang, Q., Wong, H. H., Lingampalli, N., Oliviero, F., … Robinson, W. H. (2016). CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis. Annals of the Rheumatic Diseases. -
PAD4 Inhibition is Sufficient for the Amelioration of Collagen-Induced Arthritis.
Willis, V. C., Banda, N. K., Cordova, K. N., Chandra, P. E., Robinson, W. H., Cooper, D. C., … Holers, V. M. (2017). PAD4 Inhibition is Sufficient for the Amelioration of Collagen-Induced Arthritis. Clinical and Experimental Immunology. -
Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis.
Lee, J., Luria, A., Rhodes, C., Raghu, H., Lingampalli, N., Sharpe, O., … Sokolove, J. (2016). Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis. Rheumatology (Oxford, England). -
Elevated BMI and antibodies to citrullinated proteins interact to increase rheumatoid arthritis risk and shorten time to diagnosis: A nested case-control study of women in the Nurses' Health Studies.
Tedeschi, S. K., Cui, J., Arkema, E. V., Robinson, W. H., Sokolove, J., Lingampalli, N., … Costenbader, K. H. (2016). Elevated BMI and antibodies to citrullinated proteins interact to increase rheumatoid arthritis risk and shorten time to diagnosis: A nested case-control study of women in the Nurses' Health Studies. Seminars in Arthritis and Rheumatism. -
Association of anti-citrullinated protein or peptide antibodies with left ventricular structure and function in rheumatoid arthritis.
Geraldino-Pardilla, L., Russo, C., Sokolove, J., Robinson, W. H., Zartoshti, A., Van Eyk, J., … Bathon, J. M. (2016). Association of anti-citrullinated protein or peptide antibodies with left ventricular structure and function in rheumatoid arthritis. Rheumatology (Oxford, England). -
Decreased Synovial Inflammation in Atraumatic Hip Microinstability Compared With Femoroacetabular Impingement.
Abrams, G. D., Luria, A., Sampson, J., Madding, R. A., Robinson, W. H., Safran, M. R., & Sokolove, J. (2017). Decreased Synovial Inflammation in Atraumatic Hip Microinstability Compared With Femoroacetabular Impingement. Arthroscopy , 33(3), 553–58. -
CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis
Raghu, H., Lepus, C. M., Wang, Q., Wong, H. H., Lingampalli, N., Oliviero, F., … Robinson, W. H. (2017). CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis. ANNALS OF THE RHEUMATIC DISEASES, 76(5). -
Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis
Lee, J., Luria, A., Rhodes, C., Raghu, H., Lingampalli, N., Sharpe, O., … Sokolove, J. (2017). Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis. RHEUMATOLOGY, 56(4), 644–53. -
Association of anti-citrullinated protein or peptide antibodies with left ventricular structure and function in rheumatoid arthritis
Geraldino-Pardilla, L., Russo, C., Sokolove, J., Robinson, W. H., Zartoshti, A., Van Eyk, J., … Bathon, J. M. (2017). Association of anti-citrullinated protein or peptide antibodies with left ventricular structure and function in rheumatoid arthritis. RHEUMATOLOGY, 56(4), 534–40. -
Upregulation of HERV-K is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.
Saito, T., Miyagawa, K., Chen, S.-Y. Y., Tamosiuniene, R., Wang, L., Sharp, O., … Rabinovitch, M. (2017). Upregulation of HERV-K is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension. Circulation. -
Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension.
Blum, L. K., Cao, R. R., Sweatt, A. J., Bill, M., Lahey, L. J., Hsi, A. C., … Robinson, W. H. (2018). Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension. European Journal of Immunology. -
VP4-and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans
Nair, N., Feng, N., Blum, L. K., Sanyal, M., Ding, S., Jiang, B., … Greenberg, H. B. (2017). VP4-and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans. SCIENCE TRANSLATIONAL MEDICINE, 9(395). -
Use of imatinib to treat systemic sclerosis: A prospective case series
Arefiev, K., Fiorentino, D., Chung, L., & Robinson, W. (2009). Use of imatinib to treat systemic sclerosis: A prospective case series. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 60(3), AB3. -
Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens
DeFalco, J., Harbell, M., Manning-Bog, A., Baia, G., Scholz, A., Millare, B., … Robinson, W. H. (2018). Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens. CLINICAL IMMUNOLOGY, 187, 37–45. -
Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains.
Ju, C.-H., Blum, L. K., Kongpachith, S., Lingampalli, N., Mao, R., Brodin, P., … Robinson, W. H. (2018). Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains. Clinical Immunology (Orlando, Fla.). -
Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis
Demoruelle, M. K., Bowers, E., Lahey, L. J., Sokolove, J., Purmalek, M., Seto, N. L., … Deane, K. D. (2018). Antibody Responses to Citrullinated and Noncitrullinated Antigens in the Sputum of Subjects With Rheumatoid Arthritis and Subjects at Risk for Development of Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 70(4), 516–27. -
Circulating Cytokine/Chemokine Concentrations Predict Cancer Mortality in Men with Rheumatoid Arthritis
England, B. R., Sokolove, J., Robinson, W. H., Thiele, G. M., Ganti, A. K., Sayles, H., … Mikuls, T. R. (2015). Circulating Cytokine/Chemokine Concentrations Predict Cancer Mortality in Men with Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 67. -
Cerebrospinal fluid cell phenotypic analysis from a phase 2 trial of the BHT-3009 DNA vaccine for multiple sclerosis
Nadj, C., Nadj, I., Havrdova, E., Krasulova, E., Selmaj, K., Losy, J., … Garren, H. (2008). Cerebrospinal fluid cell phenotypic analysis from a phase 2 trial of the BHT-3009 DNA vaccine for multiple sclerosis. MULTIPLE SCLEROSIS, 14, S54. -
Phase 2 follow-up results of the BHT-3009 DNA vaccine for multiple sclerosis
Havrdova, E., Krasulova, E., Nadj, C. G., Selmaj, K., Losy, J., Nadj, I., … Garren, H. (2008). Phase 2 follow-up results of the BHT-3009 DNA vaccine for multiple sclerosis. MULTIPLE SCLEROSIS JOURNAL, 14, S47. -
Using Flow and Mass Cytometry to Demonstrate Robust Tissue Processing to Query Molecular Heterogeneity in Phase 1 of the Accelerating Medicines Partnership (AMP) - RA Network
Wei, K., Rao, D., Zhang, F., Fonseka, C., Slowikowski, K., Keegan, J., … Anolik, J. H. (2017). Using Flow and Mass Cytometry to Demonstrate Robust Tissue Processing to Query Molecular Heterogeneity in Phase 1 of the Accelerating Medicines Partnership (AMP) - RA Network. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Novel Biomarkers From Peripheral Blood Mononuclear Cells Indicate Disease Activity In Rheumatoid Arthritis Patients.
Ptacek, J., Hawtin, R., Louie, B., Evensen, E., Cordeiro, J., Mittleman, B., … Bridges, S. L. (2013). Novel Biomarkers From Peripheral Blood Mononuclear Cells Indicate Disease Activity In Rheumatoid Arthritis Patients. ARTHRITIS AND RHEUMATISM, 65, S974–S975. -
Prediction Of TNF Inhibitor Response In Rheumatoid Arthritis Patients Using Single Cell Network Profiling Of Intracellular Immune Signaling
Ptacek, J., Hawtin, R., Louie, B., Evensen, E., Cordeiro, J., Mittleman, B., … Bridges, S. L. (2013). Prediction Of TNF Inhibitor Response In Rheumatoid Arthritis Patients Using Single Cell Network Profiling Of Intracellular Immune Signaling. ARTHRITIS AND RHEUMATISM, 65, S375. -
Identification of differentially expressed micro-RNA in rotator cuff tendinopathy
Hall, K. E., Sarkissian, E. J., Sharpe, O., Robinson, W. H., & Abrams, G. D. (2018). Identification of differentially expressed micro-RNA in rotator cuff tendinopathy. MLTJ-MUSCLES LIGAMENTS AND TENDONS JOURNAL, 8(1), 8–14. -
The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice
Reber, L. L., Starkl, P., Balbino, B., Sibilano, R., Gaudenzio, N., Rogalla, S., … Galli, S. J. (2017). The tyrosine kinase inhibitor imatinib mesylate suppresses uric acid crystal-induced acute gouty arthritis in mice. PLOS ONE, 12(10), e0185704. -
Men and Women Differ in the Biochemical Composition of Platelet-Rich Plasma
Xiong, G., Lingampalli, N., Koltsov, J. C. B., Leung, L. L., Bhutani, N., Robinson, W. H., & Chu, C. R. (2018). Men and Women Differ in the Biochemical Composition of Platelet-Rich Plasma. AMERICAN JOURNAL OF SPORTS MEDICINE, 46(2), 409–19. -
T cell-dependent affinity maturation and innate immune pathways differentially drive autoreactive B cell responses in rheumatoid arthritis.
Lu, D. R., McDavid, A. N., Kongpachith, S., Lingampalli, N., Glanville, J., Ju, C.-H., … Robinson, W. H. (2018). T cell-dependent affinity maturation and innate immune pathways differentially drive autoreactive B cell responses in rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). -
Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more rapid progression from preclinical to clinical rheumatoid arthritis.
Lingampalli, N., Sokolove, J., Lahey, L. J., Edison, J. D., Gilliland, W. R., Michael Holers, V., … Robinson, W. H. (2018). Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more rapid progression from preclinical to clinical rheumatoid arthritis. Clinical Immunology (Orlando, Fla.). -
Advances in Serodiagnostic Testing for Lyme Disease Are at Hand
Branda, J. A., Body, B. A., Boyle, J., Branson, B. M., Dattwyler, R. J., Fikrig, E., … Schutzer, S. E. (2018). Advances in Serodiagnostic Testing for Lyme Disease Are at Hand. CLINICAL INFECTIOUS DISEASES, 66(7), 1133–39. -
Association of Antibodies to Citrullinated Protein Antigens with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis
Hughes-Austin, J. M., Gan, R. W., Deane, K. D., Weisman, M. H., Demoruelle, M. K., Sokolove, J., … Ix, J. H. (2017). Association of Antibodies to Citrullinated Protein Antigens with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis. AMERICAN JOURNAL OF NEPHROLOGY, 46(6), 481–87. -
PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages
Zuniga, M. C., Raghuraman, G., Hitchner, E., Weyand, C., Robinson, W., & Zhou, W. (2017). PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages. ATHEROSCLEROSIS, 259, 51–59. -
Methods for Generating Multiple High-Dimensional Analyses of Cryopreserved Synovial Tissue Developed By the Accelerating Medicines Partnership RA/SLE Network
Rao, D., Donlin, L. T., Wei, K., Meednu, N., Turner, J., McGeachy, M. J., … Anolik, J. H. (2017). Methods for Generating Multiple High-Dimensional Analyses of Cryopreserved Synovial Tissue Developed By the Accelerating Medicines Partnership RA/SLE Network. ARTHRITIS & RHEUMATOLOGY, 69. -
Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study
Talabi, M. B., Mackey, R. H., Kuller, L. H., Dorman, J. S., Deane, K. D., Robinson, W. H., … Moreland, L. W. (2017). Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study. AMERICAN JOURNAL OF EPIDEMIOLOGY, 186(2), 245–54. -
Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data
Orange, D. E., Agius, P., DiCarlo, E. F., Robine, N., Geiger, H., Szymonifka, J., … Donlin, L. T. (2018). Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data. ARTHRITIS & RHEUMATOLOGY, 70(5), 690–701. -
Pharmacodynamic Analysis of Whole Blood Gene Expression over 2 Years in a Phase IIIb Head-to-Head Trial of Abatacept and Adalimumab in Patients with RA
Jabado, O., Maldonado, M. A., Schiff, M., Weinblatt, M., Fleischmann, R., Robinson, W. H., … Connolly, S. E. (2017). Pharmacodynamic Analysis of Whole Blood Gene Expression over 2 Years in a Phase IIIb Head-to-Head Trial of Abatacept and Adalimumab in Patients with RA. ARTHRITIS & RHEUMATOLOGY, 69. -
Fibroblast-like Synovial Cell Production of ED-a Fibronectin Contributes to Inflammation in Osteoarthritis
Kragstrup, T. W., Sohn, D. H., Lepus, C., Onuma, K., Wang, Q., Robinson, W. H., & Sokolove, J. (2017). Fibroblast-like Synovial Cell Production of ED-a Fibronectin Contributes to Inflammation in Osteoarthritis. ARTHRITIS & RHEUMATOLOGY, 69. -
Revealing the specificity of regulatory T cells in murine autoimmune diabetes
Spence, A., Purtha, W., Tam, J., Dong, S., Kim, Y., Ju, C.-H., … Tang, Q. (2018). Revealing the specificity of regulatory T cells in murine autoimmune diabetes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(20), 5265–70. -
Large-scale sequencing of antibody responses to Borrelia burgdorferi infection
Blum, L., Lahey, L., Kongpachith, S., Ju, C.-H., Aucott, J., Soloski, M., & Robinson, W. (2015). Large-scale sequencing of antibody responses to Borrelia burgdorferi infection. JOURNAL OF IMMUNOLOGY, 194. -
Increased IgA Plasmablasts Are Associated with Rheumatoid Arthritis-Related Autoantibodies in the Absence of Inflammatory Arthritis
Kinslow, J., Blum, L., Deane, K. D., Demoruelle, K., Parish, M. C., Kongpachith, S., … Holers, V. M. (2015). Increased IgA Plasmablasts Are Associated with Rheumatoid Arthritis-Related Autoantibodies in the Absence of Inflammatory Arthritis. ARTHRITIS & RHEUMATOLOGY, 67. -
Affinity Maturation Drives Epitope Spreading and Generation of Pro-inflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis.
Elliott, S. E., Kongpachith, S., Lingampalli, N., Adamska, J. Z., Cannon, B. J., Mao, R., … Robinson, W. H. (2018). Affinity Maturation Drives Epitope Spreading and Generation of Pro-inflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). -
Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis"
Carmona-Rivera, C., Bicker, K. L., Thompson, P. R., Buckner, J. H., Robinson, W. H., Fox, D. A., & Kaplan, M. J. (2018). Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis". SCIENCE IMMUNOLOGY, 3(21). -
Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients.
Zhao, L., Yamaguchi, Y., Ge, X., Robinson, W. H., Morser, J., & Leung, L. L. (2018). Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients. Arthritis Research & Therapy, 20(1), 132. -
Differential Expression of Hepatocyte Growth Factor (HGF) in Patients with Systemic Sclerosis-Associated Pulmonary Arterial Hypertension
Chung, L., Cramb, C., Robinson, W. H., Steen, V. D., & Zamanian, R. T. (2012). Differential Expression of Hepatocyte Growth Factor (HGF) in Patients with Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. ARTHRITIS AND RHEUMATISM, 64(10), S632. -
Differential expression of hepatocyte growth factor in patients with systemic sclerosis-associated pulmonary arterial hypertension
Sung, Y. K., Zamanian, R. T., Wagner, C. A., Robinson, W., Steen, V., & Chung, L. (2017). Differential expression of hepatocyte growth factor in patients with systemic sclerosis-associated pulmonary arterial hypertension. JOURNAL OF SCLERODERMA AND RELATED DISORDERS, 2(3), 225–30. -
Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue
Donlin, L. T., Rao, D. A., Wei, K., Slowikowski, K., McGeachy, M. J., Turner, J. D., … Anolik, J. H. (2018). Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue. ARTHRITIS RESEARCH & THERAPY, 20, 139. -
Lipids as autoantigens and therapeutic immune modulators in multiple sclerosis
Ho, P. R., Kanter, J. L., Johnson, A. M., Steinman, L., & Robinson, W. H. (2008). Lipids as autoantigens and therapeutic immune modulators in multiple sclerosis. MULTIPLE SCLEROSIS, 14, S13. -
Lipids as autoantigens and therapeutic immune modulators in autoimmune demyelination
Ho, P., Kanter, J., Johnson, A., Steinman, L., & Robinson, W. (2008). Lipids as autoantigens and therapeutic immune modulators in autoimmune demyelination. CLINICAL IMMUNOLOGY, 127, S24–S25. -
Robust B Cell Responses Predict Rapid Resolution of Lyme Disease
Blum, L. K., Adamska, J. Z., Martin, D. S., Rebman, A. W., Elliott, S. E., Cao, R. R. L., … Robinson, W. H. (2018). Robust B Cell Responses Predict Rapid Resolution of Lyme Disease. FRONTIERS IN IMMUNOLOGY, 9. -
Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients
Hughes-Austin, J. M., Deane, K. D., Giles, J. T., Derber, L. A., Zerbe, G. O., Dabelea, D. M., … Norris, J. M. (2018). Plasma adiponectin levels are associated with circulating inflammatory cytokines in autoantibody positive first-degree relatives of rheumatoid arthritis patients. PLOS ONE, 13(6), e0199578. -
Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction
Holers, V. M., Demoruelle, M. K., Kuhn, K. A., Buckner, J. H., Robinson, W. H., Okamoto, Y., … Deane, K. D. (2018). Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction. NATURE REVIEWS RHEUMATOLOGY, 14(9), 542–57. -
Synovial proteome microarray identifies citrullinated vimentin as an autoantigen in DR4-IE tg mice following immunization with citrullinated human fibrinogen.
Brintnell, W., Hill, J. A., Bell, D. A., Hueber, W., Tomooka, B. H., Robinson, W. H., & Cairns, E. (2006). Synovial proteome microarray identifies citrullinated vimentin as an autoantigen in DR4-IE tg mice following immunization with citrullinated human fibrinogen. ARTHRITIS AND RHEUMATISM, 54(9), S179. -
Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy.
Ho, P. P., Lahey, L. J., Mourkioti, F., Kraft, P. E., Filareto, A., Brandt, M., … Steinman, L. (2018). Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy. Proceedings of the National Academy of Sciences of the United States of America. -
Oral Health and Anti-Citrullinated Peptide Antibodies in Juvenile Idiopathic Arthritis
Grevich, S., Lee, P., Ringold, S., Leroux, B., Leahey, H., Yuasa, M., … Stevens, A. (2016). Oral Health and Anti-Citrullinated Peptide Antibodies in Juvenile Idiopathic Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Stem Cell Growth Factor Expression in Rheumatoid Arthritis.
Woo, Y. J., Baik, Y. A., Park, Y.-B., Lee, S.-K., Robinson, W. H., & Song, J. J. (2014). Stem Cell Growth Factor Expression in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66, S642. -
Carboxypeptidase B2 Down-Regulates Osteoclast Activation In Inflammation.
Song, J. J., Lee, S.-W., Park, Y.-B., Lee, S. K., Leung, L., & Robinson, W. H. (2013). Carboxypeptidase B2 Down-Regulates Osteoclast Activation In Inflammation. ARTHRITIS AND RHEUMATISM. WILEY-BLACKWELL. -
Direct Diagnostic Tests for Lyme Disease.
Schutzer, S. E., Body, B. A., Boyle, J., Branson, B. M., Dattwyler, R. J., Fikrig, E., … Branda, J. A. (2018). Direct Diagnostic Tests for Lyme Disease. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. -
Activation of Classical Complement Pathway is Associated with the Development of Idiopathic Pulmonary Arterial Hypertension (IPAH)
Saito, T., Sharpe, O., Harada, D., Tamosiuniene, R., Li, C. G., Nicolls, M., … Rabinovitch, M. (2012). Activation of Classical Complement Pathway is Associated with the Development of Idiopathic Pulmonary Arterial Hypertension (IPAH). CIRCULATION, 126(21). -
Antibodies to Citrullinated Protein Antigens Are Associated with Risk of Cardiovascular Disease in Community-Dwelling Women: The Multi-Ethnic Study of Atherosclerosis
Hughes-Austin, J. M., Katz, R., Firestein, G. S., Criqui, M. H., Robinson, W. H., & Ix, J. H. (2018). Antibodies to Citrullinated Protein Antigens Are Associated with Risk of Cardiovascular Disease in Community-Dwelling Women: The Multi-Ethnic Study of Atherosclerosis. ARTHRITIS & RHEUMATOLOGY, 70. -
Rheumatoid Factor Peptide Expression By Quantitative Proteomics Delineates Responsive and Resistant Clones after Treatment of Early Rheumatoid Arthritis
Wang, J. J., Murray-Brown, W., Colella, A., Smith, M. D., Chataway, T., Walker, J., … Gordon, T. (2018). Rheumatoid Factor Peptide Expression By Quantitative Proteomics Delineates Responsive and Resistant Clones after Treatment of Early Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Vertebral Compression Fractures and Antibodies to Citrullinated Vimentin in Established Rheumatoid Arthritis
Cheah, J., Carrino, J. A., Robinson, W. H., Orange, D., Szymonifka, J., Stein, E. M., & Goodman, S. M. (2018). Vertebral Compression Fractures and Antibodies to Citrullinated Vimentin in Established Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 70. -
Characterization of Preferential Recognition of a Chimeric Recombinant Proteinase 3 Variant By Anti-Neutrophil Cytoplasmic Antibodies
Thompson, G., Moura, M. C., Nelson, D., Hummel, A., Jenne, D. E., Fervenza, F., … Specks, U. (2018). Characterization of Preferential Recognition of a Chimeric Recombinant Proteinase 3 Variant By Anti-Neutrophil Cytoplasmic Antibodies. ARTHRITIS & RHEUMATOLOGY, 70. -
Serum Cytokine and Chemokine Concentrations Predict Incident Cancer in US Veterans with Rheumatoid Arthritis
England, B. R., Sayles, H., Roul, P., Ganti, A., Sokolove, J., Robinson, W. H., … Mikuls, T. R. (2018). Serum Cytokine and Chemokine Concentrations Predict Incident Cancer in US Veterans with Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 70. -
Antibody Repertoire Dynamics in Systemic Sclerosis after Myeloablative Autologous Hematopoietic Stem-Cell Transplantation or Cyclophosphamide Treatment
Adamska, J. Z., Crofford, L., Furst, D. E., Goldmuntz, E., Keyes-Elstein, L., Mayes, M. D., … Robinson, W. H. (2018). Antibody Repertoire Dynamics in Systemic Sclerosis after Myeloablative Autologous Hematopoietic Stem-Cell Transplantation or Cyclophosphamide Treatment. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Histologic and Transcriptional Evidence of Subclinical Synovial Inflammation in Rheumatoid Arthritis Patients in Clinical Remission
Orange, D., Agius, P., DiCarlo, E. F., Mirza, S. Z., Rozo, C., Pannellini, T., … Goodman, S. M. (2018). Histologic and Transcriptional Evidence of Subclinical Synovial Inflammation in Rheumatoid Arthritis Patients in Clinical Remission. ARTHRITIS & RHEUMATOLOGY, 70. -
Expanded Autoantibody Profiles Predict Treatment Response to Biologic Therapy in Rheumatoid Arthritis
Mikuls, T. R., Bath, A., England, B. R., Duryee, M. J., Hunter, C. D., Kremer, J., … Thiele, G. M. (2018). Expanded Autoantibody Profiles Predict Treatment Response to Biologic Therapy in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 70. -
Characterization of Monoclonal Anti-PAD4 Autoantibodies from Rheumatoid Arthritis Patients: Functional Implications for Citrullination and Disease Progression
Gomez, A., Kongpachith, S., Lingampalli, N., Cisar, C., & Robinson, W. H. (2018). Characterization of Monoclonal Anti-PAD4 Autoantibodies from Rheumatoid Arthritis Patients: Functional Implications for Citrullination and Disease Progression. ARTHRITIS & RHEUMATOLOGY, 70. -
Higher C6 enzyme immunoassay index values correlate with a diagnosis of noncutaneous Lyme disease.
Nigrovic, L. E., Lipsett, S. C., Molins, C. R., Wormser, G. P., Bennett, J. E., Garro, A. C., … Branda, J. A. (2018). Higher C6 enzyme immunoassay index values correlate with a diagnosis of noncutaneous Lyme disease. Diagnostic Microbiology and Infectious Disease. -
Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension.
Sweatt, A. J., Hedlin, H. K., Balasubramanian, V., Hsi, A., Blum, L. K., Robinson, W. H., … Zamanian, R. T. (2019). Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension. Circulation Research. -
Affinity Maturation of the Anti-Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis.
Kongpachith, S., Lingampalli, N., Ju, C.-H., Blum, L. K., Lu, D. R., Elliott, S. E., … Robinson, W. H. (2019). Affinity Maturation of the Anti-Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). -
Histologic and transcriptional evidence of subclinical synovial inflammation in rheumatoid arthritis patients in clinical remission.
Orange, D. E., Agius, P., DiCarlo, E. F., Mirza, S., Pannellini, T., Szymonifka, J., … Goodman, S. M. (2019). Histologic and transcriptional evidence of subclinical synovial inflammation in rheumatoid arthritis patients in clinical remission. Arthritis & Rheumatology (Hoboken, N.J.). -
Prefoldin 5 and Anti-prefoldin 5 Antibodies as Biomarkers for Uveitis in Ankylosing Spondylitis
Kwon, O. C., Lee, E.-J., Lee, J. Y., Youn, J., Kim, T.-H., Hong, S., … Kim, Y.-G. (2019). Prefoldin 5 and Anti-prefoldin 5 Antibodies as Biomarkers for Uveitis in Ankylosing Spondylitis. FRONTIERS IN IMMUNOLOGY, 10. -
Exogenous Micro-RNA and Antagomir Modulate Osteogenic Gene Expression in Tenocytes.
Xiao, M., Iglinski-Benjamin, K. C., Sharpe, O., Robinson, W. H., & Abrams, G. D. (2019). Exogenous Micro-RNA and Antagomir Modulate Osteogenic Gene Expression in Tenocytes. Experimental Cell Research. -
Protein array characterization of the specificity of the autoantibody response in experimental autoimmune encephalomyelitis: Examination of the role of epitope spreading in disease progression
Robinson, W. H., DiGennaro, C., Garren, H., Hirschberg, D., Haab, B., Brown, P., … Steinman, L. (2001). Protein array characterization of the specificity of the autoantibody response in experimental autoimmune encephalomyelitis: Examination of the role of epitope spreading in disease progression. FASEB JOURNAL, 15(5), A1064. -
Integrated serum proteome analysis of autoantibodies and cytokines delineates distinct biosignatures in subsets of patients with early RA.
Hueber, W., Tomooka, B., Bruce, B., Monach, P., Fries, J. F., van Venrooij, W., … Robinson, W. H. (2005). Integrated serum proteome analysis of autoantibodies and cytokines delineates distinct biosignatures in subsets of patients with early RA. ARTHRITIS AND RHEUMATISM, 52(9), S276–S277. -
Fibrinogen-induced arthritis in mice as a novel model for rheumatoid arthritis.
Robinson, W. H., Tomooka, B., Genovese, M. C., & Ho, P. P. (2005). Fibrinogen-induced arthritis in mice as a novel model for rheumatoid arthritis. ARTHRITIS AND RHEUMATISM, 52(9), S157. -
Signal transduction blockade with imatinib mesylate prevents and treats autoimmune arthritis
Paniagua, R., Sharpe, O., Ho, P., Chan, S., Chang, A., Tomooka, B., … Robinson, W. (2007). Signal transduction blockade with imatinib mesylate prevents and treats autoimmune arthritis. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
STRATEGY FOR ANALYSIS OF DONOR-SPECIFIC ANTIBODY REPERTOIRE: PAIRED IMMUNOGLOBULIN HEAVY AND LIGHT CHAIN ANALYSIS OF INDIVIDUAL MEMORY B CELLS
Lucia, M., Gomez, A., Bestard, O., Robinson, W., & Martinez, O. (2017). STRATEGY FOR ANALYSIS OF DONOR-SPECIFIC ANTIBODY REPERTOIRE: PAIRED IMMUNOGLOBULIN HEAVY AND LIGHT CHAIN ANALYSIS OF INDIVIDUAL MEMORY B CELLS. TRANSPLANT INTERNATIONAL, 30, 103. -
Autoimmunity to Multiple Antigens Is Expanded in at-Risk Family Members Beyond the Disease Specific Patterns of the SLE or RA Proband
James, J. A., Bean, K. M., Chen, H., Young, K. A., Bemis, E. A., Seifert, J., … Holers, V. M. (2016). Autoimmunity to Multiple Antigens Is Expanded in at-Risk Family Members Beyond the Disease Specific Patterns of the SLE or RA Proband. ARTHRITIS & RHEUMATOLOGY, 68. -
Protective and therapeutic role for alpha B-crystallin in autoimmune demyelination
Ousman, S., Tomooka, B., Van Noort, J., O'Conner, K., Wawrousek, E., Hafler, D., … Steinman, L. (2007). Protective and therapeutic role for alpha B-crystallin in autoimmune demyelination. CLINICAL IMMUNOLOGY. ACADEMIC PRESS INC ELSEVIER SCIENCE. -
Proteomic signatures of secreted proteins for the prediction of treatment response to TNF blockers in RA
Hueber, W., Tomooka, B., Batliwalla, F., Tibshirani, R., Gregersen, P., Klareskog, L., & Robinson, W. (2007). Proteomic signatures of secreted proteins for the prediction of treatment response to TNF blockers in RA. CLINICAL IMMUNOLOGY, 123, S94. -
Specific cytokine and chemokine increases precede the appearance of anti-cyclic citrullinated protein (Anti-CCP) antibodies and rheumatoid factor (RF) in the pre-clinical period of rheumatoid arthritis (RA) development.
Deane, K. D., Hueber, W., Majka, D. S., Tomooka, B. H., Gilliland, W. R., Parrish, L. A., … Holers, V. M. (2006). Specific cytokine and chemokine increases precede the appearance of anti-cyclic citrullinated protein (Anti-CCP) antibodies and rheumatoid factor (RF) in the pre-clinical period of rheumatoid arthritis (RA) development. ARTHRITIS AND RHEUMATISM, 54(9), S508. -
Monoclonal antibodies to myelin proteolipid protein (PLP) epitopes inhibit neurite outgrowth: Implications for MS
Hinojoza, J. R., Han, M. H., Eaton, M. J., Sharpe, O., Steinman, L., Robinson, W. H., & Sobel, R. A. (2006). Monoclonal antibodies to myelin proteolipid protein (PLP) epitopes inhibit neurite outgrowth: Implications for MS. BRAIN PATHOLOGY. BLACKWELL PUBLISHING. -
Lipid microarrays identify key mediators of autoimmune brain inflammation
Kanter, J. L., Johnson, A. M., Ho, P. P., Hur, E. M., Narayana, S., Robinson, W. H., & Steinman, L. (2006). Lipid microarrays identify key mediators of autoimmune brain inflammation. JOURNAL OF IMMUNOLOGY, 176, S145. -
Microarray identified lipids modulate autoimmune demyelinating disease.
Kanter, J., Johnson, A., Ho, P., Hur, E. M., Narayana, S., Steinman, L., & Robinson, W. (2006). Microarray identified lipids modulate autoimmune demyelinating disease. CLINICAL IMMUNOLOGY, 119, S29. -
Fibrinogen-induced arthritis in mice as a model for rheumatoid arthritis.
Robinson, W., Kuhn, K., Tomooka, B., Holers, V. M., & Ho, P. (2006). Fibrinogen-induced arthritis in mice as a model for rheumatoid arthritis. CLINICAL IMMUNOLOGY, 119, S16–S17. -
Lipid microarrays detect diverse anti-lipid antibodies in MS and EAE: Sulfatide immunization exacerbates EAE
Kanter, J. L., Narayana, S., Ho, P., Sobel, R., Steinman, L., & Robinson, W. H. (2005). Lipid microarrays detect diverse anti-lipid antibodies in MS and EAE: Sulfatide immunization exacerbates EAE. FASEB JOURNAL. FEDERATION AMER SOC EXP BIOL. -
Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis
Carmona-Rivera, C., Carlucci, P. M., Moore, E., Lingampalli, N., Uchtenhagen, H., James, E., … Kaplan, M. J. (2017). Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis. SCIENCE IMMUNOLOGY, 2(10). -
Synovial Fibroblast-Neutrophil Interactions Promote Pathogenic Adaptive Immunity in Rheumatoid Arthritis
Carmona-Rivera, C., Moore, E., Lingampalli, N., Uchtenhagen, H., James, E., Bicker, K. L., … Kaplan, M. (2016). Synovial Fibroblast-Neutrophil Interactions Promote Pathogenic Adaptive Immunity in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 68. -
Anti-Periodontal Bacteria Antibody Titers Are Inversely Correlated with ACPA in RA-Free Individuals with Periodontal Disease Compared to Community Controls
Weeding, E., Robinson, L., Sokolove, J., Marchesan, J., Offenbacher, S., Robinson, W. H., … Molitor, J. A. (2016). Anti-Periodontal Bacteria Antibody Titers Are Inversely Correlated with ACPA in RA-Free Individuals with Periodontal Disease Compared to Community Controls. ARTHRITIS & RHEUMATOLOGY, 68. -
Associations of Serum Anti-Citrullinated Proteins and Cytokines with Radiographic Scores in African-American Rheumatoid Arthritis Patients
Sun, D., Robinson, W. H., Cui, X., Laufer, V. A., Danila, M. I., Reynolds, R. J., … Bridges, S. L. (2016). Associations of Serum Anti-Citrullinated Proteins and Cytokines with Radiographic Scores in African-American Rheumatoid Arthritis Patients. ARTHRITIS & RHEUMATOLOGY, 68. -
Sputum Antibodies to Individual Citrullinated Protein/Peptide Antigens Are Elevated in Subjects at-Risk of Future RA and Subjects with Established Disease
Bowers, E., Demoruelle, M. K., Weisman, M., Norris, J. M., Robinson, W. H., Holers, V. M., & Deane, K. D. (2016). Sputum Antibodies to Individual Citrullinated Protein/Peptide Antigens Are Elevated in Subjects at-Risk of Future RA and Subjects with Established Disease. ARTHRITIS & RHEUMATOLOGY, 68. -
ANTIBODIES TO A SUBSET OF CITRULLINATED PEPTIDE ANTIGENS CORRELATE WITH NEUTROPHIL EXTRACELLULAR TRAP LEVELS IN THE SPUTUM OF SUBJECTS AT-RISK FOR FUTURE RA
Demoruelle, M. K., Purmalek, M., Seto, N. L., Bowers, E., Norris, J. M., Holers, V. M., … Deane, K. D. (2017). ANTIBODIES TO A SUBSET OF CITRULLINATED PEPTIDE ANTIGENS CORRELATE WITH NEUTROPHIL EXTRACELLULAR TRAP LEVELS IN THE SPUTUM OF SUBJECTS AT-RISK FOR FUTURE RA. ANNALS OF THE RHEUMATIC DISEASES, 76, A93–A94. -
Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint
Mikuls, T. R., Duryee, M. J., Rahman, R., Anderson, D. R., Sayles, H. R., Hollins, A., … Thiele, G. M. (2017). Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint. RHEUMATOLOGY, 56(10), 1794–1803. -
Suppressive Role of CD72 in Experimental Autoimmune Encephalomyelitis
Li, D. H., Creusot, R., Ousman, S. S., Fontoura, P., Sobel, R. A., Cao, T. M., … Parnes, J. R. (2007). Suppressive Role of CD72 in Experimental Autoimmune Encephalomyelitis. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
Complement component C1q limits osteoarthritis pathology by regulating macrophage activation
Raghu, H., Lingampalli, N., Wang, Q., Wong, H., Lepus, C., Mao, R., & Robinson, W. H. (2016). Complement component C1q limits osteoarthritis pathology by regulating macrophage activation. JOURNAL OF IMMUNOLOGY, 196. -
Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs
Corsiero, E., Bombardieri, M., Carlotti, E., Pratesi, F., Robinson, W., Migliorini, P., & Pitzalis, C. (2016). Single cell cloning and recombinant monoclonal antibodies generation from RA synovial B cells reveal frequent targeting of citrullinated histones of NETs. ANNALS OF THE RHEUMATIC DISEASES, 75(10), 1866–75. -
B Cell Depletion with Rituximab in Patients with Rheumatoid Arthritis: Multiplex Bead Array Reveals Kinetics of IgG and IgA Autoantibodies to Citrullinated Antigens
Cambridge, G., Lahey, L. J., Leandro, M. J., Robinson, W. H., & Sokolove, J. (2015). B Cell Depletion with Rituximab in Patients with Rheumatoid Arthritis: Multiplex Bead Array Reveals Kinetics of IgG and IgA Autoantibodies to Citrullinated Antigens. ARTHRITIS & RHEUMATOLOGY, 67. -
Associations of Serum Anti-Malondialdehyde-Acetaldehyde (MAA) Antibodies with Cardiovascular and Respiratory Mortality in Men with Rheumatoid Arthritis
England, B. R., Thiele, G. M., Duryee, M. J., Klassen, L., Sokolove, J., Robinson, W. H., … Mikuls, T. R. (2015). Associations of Serum Anti-Malondialdehyde-Acetaldehyde (MAA) Antibodies with Cardiovascular and Respiratory Mortality in Men with Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 67. -
The IL-20 Receptor Axis in Early Rheumatoid Arthritis: Novel Inflammation-Independent Links Between Autoantibody Positivity and Radiographic Progression
Kragstrup, T. W., Greisen, S., Nielsen, M. A., Rhodes, C., Stengaard-Pedersen, K., Hetland, M. L., … Deleuran, B. (2015). The IL-20 Receptor Axis in Early Rheumatoid Arthritis: Novel Inflammation-Independent Links Between Autoantibody Positivity and Radiographic Progression. ARTHRITIS & RHEUMATOLOGY, 67. -
DECADE IN REVIEW-TECHNOLOGY Technological advances transforming rheumatology
Robinson, W. H., & Mao, R. (2015). DECADE IN REVIEW-TECHNOLOGY Technological advances transforming rheumatology. NATURE REVIEWS RHEUMATOLOGY, 11(11), 626–U14. -
Flip Deficiency in Dendritic Cells Promotes Spontaneous Arthritis Mediated By Reduced Treg and Increased Autoreactive CD4(+) t Cells.
Huang, Q., Perlman, H. R., Birkett, R., Doyle, R. E., Fang, D., Haines, G. K., … Pope, R. M. (2014). Flip Deficiency in Dendritic Cells Promotes Spontaneous Arthritis Mediated By Reduced Treg and Increased Autoreactive CD4(+) t Cells. ARTHRITIS & RHEUMATOLOGY, 66, S1271. -
Associations of Toll-like Receptor (TLR)-4 Single Nucleotide Polymorphisms and Rheumatoid Arthritis Disease Progression.
Davis, M., LeVan, T., Yu, F., Sayles, H., Sokolove, J., Robinson, W. H., … Mikuls, T. R. (2014). Associations of Toll-like Receptor (TLR)-4 Single Nucleotide Polymorphisms and Rheumatoid Arthritis Disease Progression. ARTHRITIS & RHEUMATOLOGY, 66, S1071. -
Antibodies to Citrullinated Clusterin, Filaggrin, Vimentin, and Fibrinogen Are Associated with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis.
Hughes-Austin, J. M., Gan, R. W., Deane, K. D., Gregersen, P. K., Weisman, M. H., Ix, J. H., … Norris, J. M. (2014). Antibodies to Citrullinated Clusterin, Filaggrin, Vimentin, and Fibrinogen Are Associated with Blood Pressure in First-Degree Relatives of Rheumatoid Arthritis Patients: The Studies of the Etiology of Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66, S886–S887. -
A Dose Response Relationship Between Shared Epitope and ACPA Level: But Not All SE Alleles Are Created Equal.
Sokolove, J., Lahey, L. J., Wagner, C., Smolik, I., Robinson, D. B., Ferucci, E. D., … El-Gabalawy, H. (2014). A Dose Response Relationship Between Shared Epitope and ACPA Level: But Not All SE Alleles Are Created Equal. ARTHRITIS & RHEUMATOLOGY, 66, S649. -
Malondialdehyde-Acetaldehyde Adducts (MAA) and Anti-Malondialdehyde-Acetaldehyde Antibody in Rheumatoid Arthritis
Thiele, G., Duryee, M. J., Anderson, D., Klassen, L. W., Mohring, S., Young, K., … Mikuls, T. R. (2014). Malondialdehyde-Acetaldehyde Adducts (MAA) and Anti-Malondialdehyde-Acetaldehyde Antibody in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66, S646. -
Vascular Calcifications on Hand and Wrist Radiographs Are Associated with Cardiovascular Risk Factors, Antigen-Specific Anti-Citrullinated Protein Antibodies, and Mortality in Rheumatoid Arthritis.
Solow, E. B., Yu, F., Thiele, G. M., Sokolove, J., Robinson, W. H., Pruhs, Z. M., … Mikuls, T. R. (2014). Vascular Calcifications on Hand and Wrist Radiographs Are Associated with Cardiovascular Risk Factors, Antigen-Specific Anti-Citrullinated Protein Antibodies, and Mortality in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66, S370–S371. -
Netosis Induced Histone Citrullination Facilitates Onset and Propagation of Rheumatoid Arthritis.
Sohn, D. H., Onuma, K., Rhodes, C., Zhao, X., Gazitt, T., Shiao, R., … Sokolove, J. (2014). Netosis Induced Histone Citrullination Facilitates Onset and Propagation of Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66, S357–S358. -
In a Periodontal Disease Cohort without RA, Indeterminate or Low-Positive Anti-CCP-2 Antibodies Are Associated with Multiple Distinct ACPA.
Molitor, J. A., Michalowicz, B. S., Demmer, R. T., Buckner, J. H., Wener, M. H., & Robinson, W. H. (2014). In a Periodontal Disease Cohort without RA, Indeterminate or Low-Positive Anti-CCP-2 Antibodies Are Associated with Multiple Distinct ACPA. ARTHRITIS & RHEUMATOLOGY, 66, S193–S194. -
The Use of Multiplex Bead Array to Follow the Effect of Rituximab on IgG and IgA Serum Autoantibody Responses to Citrullinated Epitopes in Patients with Rheumatoid Arthritis.
Cambridge, G., Lahey, L. J., Leandro, M. J., Robinson, W. H., & Sokolove, J. (2014). The Use of Multiplex Bead Array to Follow the Effect of Rituximab on IgG and IgA Serum Autoantibody Responses to Citrullinated Epitopes in Patients with Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 66, S193. -
The Association of Fine Specificities of Anti-Citrullinated Protein Antibodies (ACPA) with disease Severity in African-Americans with RA.
Danila, M. I., Reynolds, R., Wu, G., Tiwari, H., Robinson, W. H., Sokolove, J., & Bridges, S. L. (2014). The Association of Fine Specificities of Anti-Citrullinated Protein Antibodies (ACPA) with disease Severity in African-Americans with RA. ARTHRITIS & RHEUMATOLOGY, 66, S192–S193. -
Smoking Status Is Associated with Inflammatory Cytokine Profile and Disease Activity: Decreased Inflammation and Disease Improvement with Smoking Cessation?
Sokolove, J., Sayles, H., Wagner, C., Lahey, L. J., Thiele, G. M., Robinson, W. H., … Mikuls, T. R. (2014). Smoking Status Is Associated with Inflammatory Cytokine Profile and Disease Activity: Decreased Inflammation and Disease Improvement with Smoking Cessation? ARTHRITIS & RHEUMATOLOGY, 66, S146. -
MONOCLONAL ANTIBODIES FROM CD19(+) SYNOVIAL B CELLS OF RA PATIENTS WITH TERTIARY LYMPHOID STRUCTURES DISPLAY A STRONG IMMUNOREACTIVITY TOWARDS CITRULLINATED HISTONES FROM NEUTROPHILS NETS
Corsiero, E., Carlotti, E., Wardemann, H., Robinson, W., Migliorini, P., Pratesi, F., … Bombardieri, M. (2014). MONOCLONAL ANTIBODIES FROM CD19(+) SYNOVIAL B CELLS OF RA PATIENTS WITH TERTIARY LYMPHOID STRUCTURES DISPLAY A STRONG IMMUNOREACTIVITY TOWARDS CITRULLINATED HISTONES FROM NEUTROPHILS NETS. ANNALS OF THE RHEUMATIC DISEASES, 73, A13. -
Antibodies To Citrullinated Enolase, Fibrinogen, and Vimentin Are Associated With Markers Of Endothelial Dysfunction In First-Degree Relatives Of Patients With Rheumatoid Arthritis: The Studies Of The Etiology Of Rheumatoid Arthritis
Hughes-Austin, J. M., Young, K. A., Deane, K. D., Weisman, M. H., Buckner, J. H., Mikuls, T. R., … Norris, J. M. (2013). Antibodies To Citrullinated Enolase, Fibrinogen, and Vimentin Are Associated With Markers Of Endothelial Dysfunction In First-Degree Relatives Of Patients With Rheumatoid Arthritis: The Studies Of The Etiology Of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65, S1133–S1134. -
Recombinant Monoclonal Antibodies Derived From Single CD19+Synovial B Cells Of RA Patients With Tertiary Lymphoid Structures Display a Strong Immunoreactivity Towards Citrullinated Histones
Corsiero, E., Bombardieri, M., Carlotti, E., Wardemann, H., Robinson, W. H., & Pitzalis, C. (2013). Recombinant Monoclonal Antibodies Derived From Single CD19+Synovial B Cells Of RA Patients With Tertiary Lymphoid Structures Display a Strong Immunoreactivity Towards Citrullinated Histones. ARTHRITIS AND RHEUMATISM, 65, S1127–S1128. -
The Relationship Between Anti-Citrullinated Protein Antibodies and Radiographic Damage In African-Americans With Rheumatoid Arthritis
Danila, M. I., Reynolds, R. J., Aslibekyan, S., Tamhane, A., Hughes, L. B., Sokolove, J., … Bridges, S. L. (2013). The Relationship Between Anti-Citrullinated Protein Antibodies and Radiographic Damage In African-Americans With Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65, S1028. -
Tumor Necrosis Factor Alpha Induces Anti-Citrullinated Protein Antibodies and Arthritis In Part Through Peptidyl Arginine Deiminase 4
Shelef, M. A., Sokolove, J., Wagner, C., Sackmann, E., Warner, T., Beebe, D., … Huttenlocher, A. (2013). Tumor Necrosis Factor Alpha Induces Anti-Citrullinated Protein Antibodies and Arthritis In Part Through Peptidyl Arginine Deiminase 4. ARTHRITIS AND RHEUMATISM, 65, S947. -
Chemokine Receptor Polymorphisms On Chromosome 3 Are Associated With Anticitrullinated Protein Antibody Specificities In African Americans With Rheumatoid Arthritis
Reynolds, R. J., Danila, M. I., Sokolove, J., Robinson, W. H., Conn, D. L., Jonas, B. L., … Bridges, S. L. (2013). Chemokine Receptor Polymorphisms On Chromosome 3 Are Associated With Anticitrullinated Protein Antibody Specificities In African Americans With Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65, S805. -
Decreased Plasma Levels Of Soluble CD18 Link Leukocyte Migration and Disease Activity In Spondyloarthritis
Kragstrup, T. W., Jalilian, B., Hvid, M., Ostgard, R., Schiottz-Christensen, B., Jurik, A. G., … Deleuran, B. (2013). Decreased Plasma Levels Of Soluble CD18 Link Leukocyte Migration and Disease Activity In Spondyloarthritis. ARTHRITIS AND RHEUMATISM, 65, S401. -
Role Of B Cells and/Or Autoantibodies In Pulmonary Manifestations Of Inflammatory Arthritis
Peterson, L. K., Sokolove, J., Jedlicka, P., Lahey, L. J., Robinson, W. H., & Dragone, L. L. (2013). Role Of B Cells and/Or Autoantibodies In Pulmonary Manifestations Of Inflammatory Arthritis. ARTHRITIS AND RHEUMATISM, 65, S395–S396. -
Alveolar Bone Loss Is Associated With Disease Activity and ACPA Expression In Rheumatoid Arthritis
Mikuls, T. R., Payne, J., Yu, F., Thiele, G. M., Gonzalez, S., Markt, J., … O'Dell, J. R. (2013). Alveolar Bone Loss Is Associated With Disease Activity and ACPA Expression In Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65, S345. -
IgM Rheumatoid Factor As a Potentiator Of Anti-Citrullinated Protein Antibody Mediated Inflammation In Rheumatoid Arthritis
Sokolove, J., Cheng, D., Johnson, D. S., Mikuls, T. R., & Robinson, W. H. (2013). IgM Rheumatoid Factor As a Potentiator Of Anti-Citrullinated Protein Antibody Mediated Inflammation In Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 65, S343–S344. -
Autoimmune Attack Takes Your Breath Away
Lindstrom, T. M., & Robinson, W. H. (2013). Autoimmune Attack Takes Your Breath Away. SCIENCE TRANSLATIONAL MEDICINE, 5(206), 206fs36. -
An Expanded Repertoire of Anti-Citrullinated Peptide Antibodies Is Associated with Interstitial Lung Disease in Rheumatoid Arthritis
Giles, J. T., Danoff, S., Sokolove, J., Winchester, R., Pappas, D. A., Cramb, C., … Bathon, J. M. (2012). An Expanded Repertoire of Anti-Citrullinated Peptide Antibodies Is Associated with Interstitial Lung Disease in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(10), S1127. -
Fine-Specificity of Anti-Citrullinated Peptide Auto-Antibodies: Associations with Cardiac Structure and Function in Rheumatoid Arthritis.
Geraldino-Pardilla, L., Giles, J. T., Sokolove, J., Robinson, W. H., & Bathon, J. M. (2012). Fine-Specificity of Anti-Citrullinated Peptide Auto-Antibodies: Associations with Cardiac Structure and Function in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(10), S1072. -
Adiponectin Is Associated with Pro-Inflammatory Cytokines in Autoantibody Positive First-Degree Relatives (FDRs) of Patients with Rheumatoid Arthritis.
Hughes-Austin, J. M., Deane, K. D., Derber, L. A., Zerbe, G. O., Dabelea, D. M., Sokolove, J., … Norris, J. M. (2012). Adiponectin Is Associated with Pro-Inflammatory Cytokines in Autoantibody Positive First-Degree Relatives (FDRs) of Patients with Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 64(10), S887. -
Citrullination within the Atherosclerotic Plaque: A New Potential Target for Anti-Citrullinated Protein Antibodies
Sokolove, J., Share, O., Brennan, M., Lahey, L. J., Kao, A. H., Krishnan, E., … Robinson, W. H. (2012). Citrullination within the Atherosclerotic Plaque: A New Potential Target for Anti-Citrullinated Protein Antibodies. ARTHRITIS AND RHEUMATISM, 64(10), S723. -
Smoking Status Is Associated with Inflammatory Cytokine Profile and Disease Activity in Anti-Citrullinated Protein Antibody Positive Rheumatoid Arthritis: Decreased Inflammation and Disease Improvement with Smoking Cessation?
Cramb, C., Sokolove, J., Thiele, G. M., Kerr, G. S., Cannon, G. W., Reimold, A. M., … Robinson, W. H. (2012). Smoking Status Is Associated with Inflammatory Cytokine Profile and Disease Activity in Anti-Citrullinated Protein Antibody Positive Rheumatoid Arthritis: Decreased Inflammation and Disease Improvement with Smoking Cessation? ARTHRITIS AND RHEUMATISM, 64(10), S508–S509. -
Citrullination of fibrinogen: generation of neoepitopes and enhancement of immunostimulatory properties
Robinson, W. H., & Sokolove, J. (2012). Citrullination of fibrinogen: generation of neoepitopes and enhancement of immunostimulatory properties. ARTHRITIS RESEARCH & THERAPY, 14. -
Smoking and Periodontal Status Are Associated with ACPA Fine Specificity and Levels of Inflammatory Cytokines in Rheumatoid Arthritis: The ARIC Study.
Bromberg, R., Sokolove, J., Lahey, L. J., Alonso, A., Wener, M. H., Gersuk, V. H., … Molitor, J. A. (2011). Smoking and Periodontal Status Are Associated with ACPA Fine Specificity and Levels of Inflammatory Cytokines in Rheumatoid Arthritis: The ARIC Study. ARTHRITIS AND RHEUMATISM, 63(10), S845–S846. -
Development of a High-Throughput, Multiplex Assay for Profiling the Autoantibody Fine Specificity in Rheumatoid Arthritis
Zhao, X., Eastman, P. S., Qureshi, F., Manning, W. C., Robinson, W., & Hesterberg, L. K. (2011). Development of a High-Throughput, Multiplex Assay for Profiling the Autoantibody Fine Specificity in Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 63(10), S686. -
Serum Cytokine Levels Predict Mortality Among Postmenopausal Women Reporting Rheumatoid Arthritis.
Sokolove, J., Robinson, W. H., Walitt, B. T., Deane, K. D., Chang, Y., Tracy, R., … Mackey, R. (2011). Serum Cytokine Levels Predict Mortality Among Postmenopausal Women Reporting Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 63(10), S144. -
Rheumatoid Arthritis Case Validation Strategies in Large Research Databases: The Women's Health Initiative Experience.
Walitt, B. T., Mackey, R., Kuller, L., Deane, K. D., Robinson, W., Holers, V. M., … Moreland, L. W. (2011). Rheumatoid Arthritis Case Validation Strategies in Large Research Databases: The Women's Health Initiative Experience. ARTHRITIS AND RHEUMATISM, 63(10), S120–S121. -
The Association Between Rheumatoid Factor and Predisposing Factors for Atherogenesis in First-Degree Relatives without Rheumatoid Arthritis: Studies of the Etiology of Rheumatoid Arthritis
Hughes-Austin, J. M., Deane, K. D., Derber, L. A., Zerbe, G. O., Dabelea, D. M., Eckel, R. H., … Norris, J. M. (2011). The Association Between Rheumatoid Factor and Predisposing Factors for Atherogenesis in First-Degree Relatives without Rheumatoid Arthritis: Studies of the Etiology of Rheumatoid Arthritis. ARTHRITIS AND RHEUMATISM, 63(10), S34. -
EGFR Inhibition Ameliorates Murine Collagen-induced Arthritis
Swanson, C., & Robinson, W. H. (2010). EGFR Inhibition Ameliorates Murine Collagen-induced Arthritis. CLINICAL IMMUNOLOGY, 135, S59. -
Citrullinated Fibrinogen Stimulates TNF Release via TLR4 and Citrullinated Fibrinogen Immune Complexes Co-stimulate Through TLR4 and the Fc Gamma Receptor
Sokolove, J., Zhao, X., & Robinson, W. (2010). Citrullinated Fibrinogen Stimulates TNF Release via TLR4 and Citrullinated Fibrinogen Immune Complexes Co-stimulate Through TLR4 and the Fc Gamma Receptor. CLINICAL IMMUNOLOGY, 135, S38–S39. -
Citrullinated Fibrinogen Stimulates TNF Release via TLR4 and Citrullinated Fibrinogen Immune Complexes Co-stimulate through TLR4 and the Fc Gamma Receptor
Sokolove, J., Zhao, X., & Robinson, W. (2010). Citrullinated Fibrinogen Stimulates TNF Release via TLR4 and Citrullinated Fibrinogen Immune Complexes Co-stimulate through TLR4 and the Fc Gamma Receptor. CLINICAL IMMUNOLOGY, 135, S7. -
Cardiac Glycosides as Anti-inflammatory Agents in Collagen Arthritis
Stein, E., & Robinson, W. (2009). Cardiac Glycosides as Anti-inflammatory Agents in Collagen Arthritis. CLINICAL IMMUNOLOGY, 131, S74. -
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
James, J. A., Chen, H., Young, K. A., Bemis, E. A., Seifert, J., Bourn, R. L., … Holers, V. M. (2019). Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. EBioMedicine. -
B cell checkpoints in autoimmune rheumatic diseases.
Rubin, S. J., Bloom, M. S., & Robinson, W. H. (2019). B cell checkpoints in autoimmune rheumatic diseases. Nature Reviews. Rheumatology. -
Development of a Multiantigen Panel for Improved Detection of Borrelia burgdorferi Infection in Early Lyme Disease.
Lahey, L. J., Panas, M. W., Mao, R., Delanoy, M., Flanagan, J. J., Binder, S. R., … Robinson, W. H. (2015). Development of a Multiantigen Panel for Improved Detection of Borrelia burgdorferi Infection in Early Lyme Disease. Journal of Clinical Microbiology, 53(12), 3834–41. -
Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative.
Mackey, R. H., Kuller, L. H., Deane, K. D., Walitt, B. T., Chang, Y.-F. F., Holers, V. M., … Moreland, L. W. (2015). Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative. Arthritis & Rheumatology (Hoboken, N.J.), 67(9), 2311–22. -
Robust B Cell Responses Predict Rapid Resolution of Lyme Disease.
Blum, L. K., Adamska, J. Z., Martin, D. S., Rebman, A. W., Elliott, S. E., Cao, R. R., … Robinson, W. H. (2018). Robust B Cell Responses Predict Rapid Resolution of Lyme Disease. Frontiers in Immunology, 9, 1634. -
A prospective study of the development of inflammatory arthritis in the family members of Indigenous North American people with rheumatoid arthritis.
Tanner, S., Dufault, B., Smolik, I., Meng, X., Anaparti, V., Hitchon, C., … El-Gabalawy, H. (2019). A prospective study of the development of inflammatory arthritis in the family members of Indigenous North American people with rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). -
Prefoldin 5 and Anti-prefoldin 5 Antibodies as Biomarkers for Uveitis in Ankylosing Spondylitis.
Kwon, O. C., Lee, E.-J. J., Lee, J. Y., Youn, J., Kim, T.-H. H., Hong, S., … Kim, Y.-G. G. (2019). Prefoldin 5 and Anti-prefoldin 5 Antibodies as Biomarkers for Uveitis in Ankylosing Spondylitis. Frontiers in Immunology, 10, 384. -
Role of protein phosphatase magnesium-dependent 1A and anti-protein phosphatase magnesium-dependent 1A autoantibodies in ankylosing spondylitis.
Kim, Y.-G. G., Sohn, D. H., Zhao, X., Sokolove, J., Lindstrom, T. M., Yoo, B., … Robinson, W. H. (2014). Role of protein phosphatase magnesium-dependent 1A and anti-protein phosphatase magnesium-dependent 1A autoantibodies in ankylosing spondylitis. Arthritis & Rheumatology (Hoboken, N.J.), 66(10), 2793–2803. -
Platelet-Rich Plasma (PRP) from Older Males with Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation.
O'Donnell, C., Migliore, E., Grandi, F. C., Koltsov, J., Lingampalli, N., Cisar, C., … Chu, C. R. (2019). Platelet-Rich Plasma (PRP) from Older Males with Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. -
Affinity Maturation of the Anti-Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis
Kongpachith, S., Lingampalli, N., Ju, C.-H., Blum, L. K., Lu, D. R., Elliott, S. E., … Robinson, W. H. (2019). Affinity Maturation of the Anti-Citrullinated Protein Antibody Paratope Drives Epitope Spreading and Polyreactivity in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 71(4), 507–17. -
Exogenous micro-RNA and antagomir modulate osteogenic gene expression in tenocytes
Xiao, M., Iglinski-Benjamin, K. C., Sharpe, O., Robinson, W. H., & Abrams, G. D. (2019). Exogenous micro-RNA and antagomir modulate osteogenic gene expression in tenocytes. EXPERIMENTAL CELL RESEARCH, 378(2), 119–23. -
Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension
Blum, L. K., Cao, R. R. L., Sweatt, A. J., Bill, M., Lahey, L. J., Hsi, A. C., … Robinson, W. H. (2018). Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension. EUROPEAN JOURNAL OF IMMUNOLOGY, 48(5), 874–84. -
B cell checkpoints in autoimmune rheumatic diseases
Rubin, S. J. S., Bloom, M. S., & Robinson, W. H. (2019). B cell checkpoints in autoimmune rheumatic diseases. NATURE REVIEWS RHEUMATOLOGY, 15(5), 303–15. -
Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy
Ho, P. P., Lahey, L. J., Mourkioti, F., Kraft, P. E., Filareto, A., Brandt, M., … Steinman, L. (2018). Engineered DNA plasmid reduces immunity to dystrophin while improving muscle force in a model of gene therapy of Duchenne dystrophy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(39), E9182–E9191. -
Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients
Zhao, L., Yamaguchi, Y., Ge, X., Robinson, W. H., Morser, J., & Leung, L. L. K. (2018). Chemerin 156F, generated by chymase cleavage of prochemerin, is elevated in joint fluids of arthritis patients. ARTHRITIS RESEARCH & THERAPY, 20. -
IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis.
Wang, Q., Lepus, C. M., Raghu, H., Reber, L. L., Tsai, M. M., Wong, H. H., … Robinson, W. H. (2019). IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis. ELife, 8. -
Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients
James, J. A., Chen, H., Young, K. A., Bemis, E. A., Seifert, J., Bourn, R. L., … Holers, V. M. (2019). Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients. EBIOMEDICINE, 42, 76–85. -
IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis
Wang, Q., Lepus, C. M., Raghu, H., Reber, L. L., Tsai, M. M., Wong, H. H., … Robinson, W. H. (2019). IgE-mediated mast cell activation promotes inflammation and cartilage destruction in osteoarthritis. ELIFE, 8. -
Direct Diagnostic Tests for Lyme Disease
Schutzer, S. E., Body, B. A., Boyle, J., Branson, B. M., Dattwyler, R. J., Fikrig, E., … Branda, J. A. (2019). Direct Diagnostic Tests for Lyme Disease. CLINICAL INFECTIOUS DISEASES, 68(6), 1052–57. -
Affinity Maturation Drives Epitope Spreading and Generation of Proinflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis
Elliott, S. E., Kongpachith, S., Lingampalli, N., Adamska, J. Z., Cannon, B. J., Mao, R., … Robinson, W. H. (2018). Affinity Maturation Drives Epitope Spreading and Generation of Proinflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 70(12), 1946–58. -
T Cell-Dependent Affinity Maturation and Innate Immune Pathways Differentially Drive Autoreactive B Cell Responses in Rheumatoid Arthritis
Lu, D. R., McDavid, A. N., Kongpachith, S., Lingampalli, N., Glanville, J., Ju, C.-H., … Robinson, W. H. (2018). T Cell-Dependent Affinity Maturation and Innate Immune Pathways Differentially Drive Autoreactive B Cell Responses in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 70(11), 1732–44. -
Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more updates rapid progression from preclinical to clinical rheumatoid arthritis
Lingampalli, N., Sokolove, J., Lahey, L. J., Edison, J. D., Gilliland, W. R., Holers, V. M., … Robinson, W. H. (2018). Combination of anti-citrullinated protein antibodies and rheumatoid factor is associated with increased systemic inflammatory mediators and more updates rapid progression from preclinical to clinical rheumatoid arthritis. CLINICAL IMMUNOLOGY, 195, 119–26. -
Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains
Ju, C.-H., Blum, L. K., Kongpachith, S., Lingampalli, N., Mao, R., Brodin, P., … Robinson, W. H. (2018). Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains. CLINICAL IMMUNOLOGY, 193, 70–79. -
Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension
Sweatt, A. J., Hedlin, H. K., Balasubramanian, V., Hsi, A., Blum, L. K., Robinson, W. H., … Zamanian, R. T. (2019). Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension. CIRCULATION RESEARCH, 124(6), 904–19. -
Increased somatic hypermutation in the immunoglobulin sequences of melanoma patients who have durable response to checkpoint inhibitor therapy
Ngan Nguyen, Mamchak, A., Severgnini, M., Williamson, K. S., Wu, X., Drabek, E. F., … Hodi, F. S. (2018). Increased somatic hypermutation in the immunoglobulin sequences of melanoma patients who have durable response to checkpoint inhibitor therapy. CANCER RESEARCH, 78(13). -
Mining the cancer immuno-responsome: The identification of functional antitumor antibodies from patients receiving checkpoint inhibitors
Baia, G., Manning-Bog, A., Scholz, A., DeFalco, J., Harbell, M., Zhang, D., … Robinson, W. H. (2018). Mining the cancer immuno-responsome: The identification of functional antitumor antibodies from patients receiving checkpoint inhibitors. CANCER RESEARCH, 78(13). -
Paraneoplastic and Therapy-Related Immune Complications in Thymic Malignancies.
Lippner, E. A., Lewis, D. B., Robinson, W. H., & Katsumoto, T. R. (2019). Paraneoplastic and Therapy-Related Immune Complications in Thymic Malignancies. Current Treatment Options in Oncology, 20(7), 62. -
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
Zhang, F., Wei, K., Slowikowski, K., Fonseka, C. Y., Rao, D. A., Kelly, S., … Utz, P. J. (2019). Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. NATURE IMMUNOLOGY, 20(7), 928-+. -
ASTHMA AND ELEVATION OF ANTI-CITRULLINATED PROTEIN ANTIBODIES PRIOR TO THE ONSET OF RHEUMATOID ARTHRITIS
Zaccardelli, A., Liu, X., Ford, J., Tedeschi, S., Cui, J., Lu, B., … Sparks, J. (2019). ASTHMA AND ELEVATION OF ANTI-CITRULLINATED PROTEIN ANTIBODIES PRIOR TO THE ONSET OF RHEUMATOID ARTHRITIS. ANNALS OF THE RHEUMATIC DISEASES, 78, 642. -
ASSOCIATIONS OF BASELINE CLINICAL AND BIOMARKER FACTORS WITH SYMPTOMS AND FUTURE DEVELOPMENT OF CLINICALLY-APPARENT RHEUMATOID ARTHRITIS IN AN ACPA POSITIVE COHORT
Deane, K. D., Nagpal, S., Rao, N., Baribaud, F., Vratsanos, G., James, E. A., … Holers, V. M. (2019). ASSOCIATIONS OF BASELINE CLINICAL AND BIOMARKER FACTORS WITH SYMPTOMS AND FUTURE DEVELOPMENT OF CLINICALLY-APPARENT RHEUMATOID ARTHRITIS IN AN ACPA POSITIVE COHORT. ANNALS OF THE RHEUMATIC DISEASES, 78, 1105. -
Histologic and Transcriptional Evidence of Subclinical Synovial Inflammation in Patients With Rheumatoid Arthritis in Clinical Remission
Orange, D. E., Agius, P., DiCarlo, E. F., Mirza, S. Z., Pannellini, T., Szymonifka, J., … Goodman, S. M. (2019). Histologic and Transcriptional Evidence of Subclinical Synovial Inflammation in Patients With Rheumatoid Arthritis in Clinical Remission. ARTHRITIS & RHEUMATOLOGY, 71(7), 1034–41. -
Expanded IgG lineages from antibody repertoires of melanoma patients to reveal anti-tumor antibodies.
Minor, D. R., Defalco, J., Harbell, M., Scholz, A., Manning-Bog, A., Sokolove, J., … Emerling, D. (2016). Expanded IgG lineages from antibody repertoires of melanoma patients to reveal anti-tumor antibodies. JOURNAL OF CLINICAL ONCOLOGY, 34(15). -
PREFERENTIAL BINDING TO AN UNEXPECTED EPITOPE OF A CHIMERIC RECOMBINANT PROTEINASE 3 VARIANT BY ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODIES
Thompson, G., Moura, M. C., Nelson, D., Fussner, L., Hummel, A., Jenne, D., … Specks, U. (2019). PREFERENTIAL BINDING TO AN UNEXPECTED EPITOPE OF A CHIMERIC RECOMBINANT PROTEINASE 3 VARIANT BY ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODIES. RHEUMATOLOGY, 58. -
A Prospective Study of the Development of Inflammatory Arthritis in the Family Members of Indigenous North American People With Rheumatoid Arthritis
Tanner, S., Dufault, B., Smolik, I., Meng, X., Anaparti, V., Hitchon, C., … El-Gabalawy, H. (2019). A Prospective Study of the Development of Inflammatory Arthritis in the Family Members of Indigenous North American People With Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. -
Antigen-specific tolerance to self-antigens in protein replacement therapy, gene therapy and autoimmunity.
Steinman, L., Ho, P. P., Robinson, W. H., Utz, P. J., & Villoslada, P. (2019). Antigen-specific tolerance to self-antigens in protein replacement therapy, gene therapy and autoimmunity. Current Opinion in Immunology, 61, 46–53. -
Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.
Byrd, A. S., Carmona-Rivera, C., O'Neil, L. J., Carlucci, P. M., Cisar, C., Rosenberg, A. Z., … Kaplan, M. J. (2019). Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa. Science Translational Medicine, 11(508). -
Autoantibodies to protein-arginine deiminase (PAD) 4 in rheumatoid arthritis: immunological and clinical significance, and potential for precision medicine.
Martinez-Prat, L., Palterer, B., Vitiello, G., Parronchi, P., Robinson, W. H., & Mahler, M. (2019). Autoantibodies to protein-arginine deiminase (PAD) 4 in rheumatoid arthritis: immunological and clinical significance, and potential for precision medicine. Expert Review of Clinical Immunology. -
Dysregulated integrin aVß3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis.
Wang, Q., Onuma, K., Liu, C., Wong, H., Bloom, M. S., Elliott, E. E., … Robinson, W. H. (2019). Dysregulated integrin aVß3 and CD47 signaling promotes joint inflammation, cartilage breakdown, and progression of osteoarthritis. JCI Insight, 4(18). -
Immunomodulatory receptors are differentially expressed in B and T cell subsets relevant to autoimmune disease.
Murphy, K. A., Bhamidiphati, K., Rubin, S. J., Kipp, L., Robinson, W. H., & Lanz, T. V. (2019). Immunomodulatory receptors are differentially expressed in B and T cell subsets relevant to autoimmune disease. Clinical Immunology (Orlando, Fla.), 108276. -
Remote Activation of a Latent Epitope in an Autoantigen Decoded With Simulated B-Factors.
Pang, Y.-P., Casal Moura, M., Thompson, G. E., Nelson, D. R., Hummel, A. M., Jenne, D. E., … Specks, U. (2019). Remote Activation of a Latent Epitope in an Autoantigen Decoded With Simulated B-Factors. Frontiers in Immunology, 10, 2467. -
Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis.
Zaccardelli, A., Liu, X., Ford, J. A., Cui, J., Lu, B., Chu, S. H., … Sparks, J. A. (2019). Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis. Arthritis Research & Therapy, 21(1), 246. -
ATRC-101: A first-in-class engineered fully human monoclonal antibody that targets a tumor-restricted ribonucleoprotein complex
Del-alco, J., Emerling, D., Manning-Bog, A., Baia, G., Lippow, S., Scholz, A., … Greenberg, N. (2019). ATRC-101: A first-in-class engineered fully human monoclonal antibody that targets a tumor-restricted ribonucleoprotein complex. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 7. -
The intracellular protein phosphatase magnesium-dependent 1A negatively regulates osteoclast commitment.
Kwon, O. C., Choi, B., Lee, E.-J., Park, J.-E., Lee, E.-J., Kim, E.-Y., … Chang, E.-J. (2019). The intracellular protein phosphatase magnesium-dependent 1A negatively regulates osteoclast commitment. Arthritis & Rheumatology (Hoboken, N.J.). -
Characterizing the BCR repertoire in immune-mediated diseases.
Ramadoss, N. S., & Robinson, W. H. (2019). Characterizing the BCR repertoire in immune-mediated diseases. Nature Reviews. Rheumatology. -
Protein phosphatase magnesium-dependent 1A induces inflammation in rheumatoid arthritis.
Lee, B., Song, Y. S., Rhodes, C., Goh, T. S., Roh, J. S., Jeong, H., … Robinson, W. H. (2019). Protein phosphatase magnesium-dependent 1A induces inflammation in rheumatoid arthritis. Biochemical and Biophysical Research Communications. -
Fibroblast-like synovial cell production of extra domain A fibronectin associates with inflammation in osteoarthritis.
Kragstrup, T. W., Sohn, D. H., Lepus, C. M., Onuma, K., Wang, Q., Robinson, W. H., & Sokolove, J. (2019). Fibroblast-like synovial cell production of extra domain A fibronectin associates with inflammation in osteoarthritis. BMC Rheumatology, 3, 46. -
Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation
O'Donnell, C., Migliore, E., Grandi, F. C., Koltsov, J., Lingampalli, N., Cisar, C., … Chu, C. R. (2019). Platelet-Rich Plasma (PRP) From Older Males With Knee Osteoarthritis Depresses Chondrocyte Metabolism and Upregulates Inflammation. JOURNAL OF ORTHOPAEDIC RESEARCH, 37(8), 1760–70. -
Elevated anti-citrullinated protein antibodies prior to rheumatoid arthritis diagnosis and risks for chronic obstructive pulmonary disease or asthma.
Zaccardelli, A., Liu, X., Ford, J. A., Cui, J., Lu, B., Chu, S. H., … Sparks, J. A. (2020). Elevated anti-citrullinated protein antibodies prior to rheumatoid arthritis diagnosis and risks for chronic obstructive pulmonary disease or asthma. Arthritis Care & Research. -
Antibody Repertoire Sequencing, Antigen Array Analysis, and Cytokine Profiling of Blood from Individuals at High-risk for RA Reveals Candidate Immunoglobulin V Genes, ACPA, and Cytokines That May Promote the Transition to Arthritis
Iyer, R., Zia, A., Bloom, M., Nagpal, S., Rao, N., Baribaud, F., … Robinson, W. (2019). Antibody Repertoire Sequencing, Antigen Array Analysis, and Cytokine Profiling of Blood from Individuals at High-risk for RA Reveals Candidate Immunoglobulin V Genes, ACPA, and Cytokines That May Promote the Transition to Arthritis. ARTHRITIS & RHEUMATOLOGY, 71. -
Associations Between Circulating Cytokines and Incident Inflammatory Arthritis in an Anti-citrullinated Protein Antibody Positive Population
Polinski, K., Bemis, E., Demoruelle, M. K., Feser, M., Moss, L. K., Seifert, J., … Norris, J. (2019). Associations Between Circulating Cytokines and Incident Inflammatory Arthritis in an Anti-citrullinated Protein Antibody Positive Population. ARTHRITIS & RHEUMATOLOGY, 71. -
Clinical and Biomarker Factor Associations with Symptoms and Future Development of RA: TIP-RA Collective
Deane, K., Nagpal, S., Holers, V. M., Firestein, G., Boyle, D., Seifert, J., … Vratsanos, G. (2019). Clinical and Biomarker Factor Associations with Symptoms and Future Development of RA: TIP-RA Collective. ARTHRITIS & RHEUMATOLOGY, 71. -
Differential Methylation of Peripheral Blood Adaptive Immune Cells in Individuals at High Risk for RA and with Early RA Compared with Controls Identifies Pathways Important in Transition to Arthritis
Ai, R., Boyle, D., Hammaker, D., Deane, K., Holers, V. M., Matti, A., … Firestein, G. (2019). Differential Methylation of Peripheral Blood Adaptive Immune Cells in Individuals at High Risk for RA and with Early RA Compared with Controls Identifies Pathways Important in Transition to Arthritis. ARTHRITIS & RHEUMATOLOGY, 71. -
Elevation of Anti-Citrullinated Protein Antibodies Prior to Rheumatoid Arthritis Onset and Risks for Developing Chronic Obstructive Pulmonary Disease or Asthma
Zaccardelli, A., Liu, X., Ford, J., Cui, J., Lu, B., Chu, S. H., … Sparks, J. (2019). Elevation of Anti-Citrullinated Protein Antibodies Prior to Rheumatoid Arthritis Onset and Risks for Developing Chronic Obstructive Pulmonary Disease or Asthma. ARTHRITIS & RHEUMATOLOGY, 71. -
Differences in the Phenotypic Landscape and Antigen Specificity of CD4+T Cells Are Present in CCP plus Subjects Before the Onset of Rheumatoid Arthritis
Muir, V., Rims, C., Deane, K., Carlin, J., Posso, S., Nagpal, S., … Buckner, J. (2019). Differences in the Phenotypic Landscape and Antigen Specificity of CD4+T Cells Are Present in CCP plus Subjects Before the Onset of Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY, 71. -
B cells in rheumatoid arthritis synovial tissues encode focused antibody repertoires that include antibodies that stimulate macrophage TNF-a production.
Elliott, S. E., Kongpachith, S., Lingampalli, N., Adamska, J. Z., Cannon, B. J., Blum, L. K., … Robinson, W. H. (2020). B cells in rheumatoid arthritis synovial tissues encode focused antibody repertoires that include antibodies that stimulate macrophage TNF-a production. Clinical Immunology (Orlando, Fla.), 108360. -
Impact on immune effectors of anti-tumor antibodies isolated from cancer patients.
Manning-Bog, A., Baia, G., Defalco, J., Aydin, I. T., Harbell, M. G., Zuno-Mitchell, P., … Emerling, D. (2018). Impact on immune effectors of anti-tumor antibodies isolated from cancer patients. JOURNAL OF CLINICAL ONCOLOGY, 36(15). -
Osteoarthritis risk is reduced after treatment with ticagrelor compared to clopidogrel: a propensity score matching analysis.
Baker, M. C., Weng, Y., William, R. H., Ahuja, N., & Rohatgi, N. (2020). Osteoarthritis risk is reduced after treatment with ticagrelor compared to clopidogrel: a propensity score matching analysis. Arthritis & Rheumatology (Hoboken, N.J.). -
PRIME Time in Rheumatoid Arthritis.
Gravallese, E. M., & Robinson, W. H. (2020). PRIME Time in Rheumatoid Arthritis. The New England Journal of Medicine, 383(3), 278–79. -
Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients.
Kuerten, S., Lanz, T. V., Lingampalli, N., Lahey, L. J., Kleinschnitz, C., Mäurer, M., … Steinman, L. (2020). Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients. Proceedings of the National Academy of Sciences of the United States of America. -
Soaking of Autologous Tendon Grafts in Vancomycin Before Implantation Does Not Lead to Tenocyte Cytotoxicity.
Xiao, M., Leonardi, E. A., Sharpe, O., Sherman, S. L., Safran, M. R., Robinson, W. H., & Abrams, G. D. (2020). Soaking of Autologous Tendon Grafts in Vancomycin Before Implantation Does Not Lead to Tenocyte Cytotoxicity. The American Journal of Sports Medicine, 363546520951815. -
Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease.
Mosel, M. R., Rebman, A. W., Carolan, H. E., Montenegro, T., Lovari, R., Schutzer, S. E., … Aucott, J. N. (2020). Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease. Journal of Clinical Microbiology. -
Associations between an expanded autoantibody profile and treatment responses to biologic therapies in patients with rheumatoid arthritis.
Petro, A. D., Dougherty, J., England, B. R., Sayles, H., Duryee, M. J., Hunter, C. D., … Mikuls, T. R. (2020). Associations between an expanded autoantibody profile and treatment responses to biologic therapies in patients with rheumatoid arthritis. International Immunopharmacology, 91, 107260. -
Modeling human adaptive immune responses with tonsil organoids.
Wagar, L. E., Salahudeen, A., Constantz, C. M., Wendel, B. S., Lyons, M. M., Mallajosyula, V., … Davis, M. M. (2021). Modeling human adaptive immune responses with tonsil organoids. Nature Medicine. -
Ultrasound in Knee Osteoarthritis: Reader Performance, Sonographic Features, and Correlation with Radiographic Findings
Nwawka, O., Lee, S., Lin, B., Ibrahim, S., Brantner, C., Sculco, P., … Mehta, B. (2020). Ultrasound in Knee Osteoarthritis: Reader Performance, Sonographic Features, and Correlation with Radiographic Findings. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Fine Specificity Anti-Citrullinated Protein Antibodies as Biomarkers for Prediction of Incident Rheumatoid Arthritis-Associated Interstitial Lung Disease
Kronzer, V., Huang, W., Dellaripa, P., Huang, S., Feathers, V., Lu, B., … Sparks, J. (2020). Fine Specificity Anti-Citrullinated Protein Antibodies as Biomarkers for Prediction of Incident Rheumatoid Arthritis-Associated Interstitial Lung Disease. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Vitamin D Polygenetic Risk Score and the Association with RA Autoantibodies Among First-Degree Relatives of RA Subjects
Bemis, E., Young, K., Seifert, J., Feser, M., Deane, K. D., Demoruelle, M. K., … Norris, J. (2020). Vitamin D Polygenetic Risk Score and the Association with RA Autoantibodies Among First-Degree Relatives of RA Subjects. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Higher Baseline Fine-Specificity ACPAs Predict Greater Treatment Response with Abatacept plus MTX versus MTX Monotherapy in Seropositive RA: A Post Hoc Analysis
Robinson, W., Wu, C., Hu, S., Connolly, S., & Mukherjee, S. (2020). Higher Baseline Fine-Specificity ACPAs Predict Greater Treatment Response with Abatacept plus MTX versus MTX Monotherapy in Seropositive RA: A Post Hoc Analysis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Factors Associated with an Increased Risk of Imminent Rheumatoid Arthritis in ACPA plus Individuals
Kim, H.-A., Peterson, R., Firestein, G., Boyle, D., Buckner, J., Posso, S., … Deane, K. D. (2020). Factors Associated with an Increased Risk of Imminent Rheumatoid Arthritis in ACPA plus Individuals. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Bacterial Families Lachnospiraceae/Ruminococcaceae Are Immunologically Targeted in Individuals At-risk for RA and a Specific Strain Is Arthritogenic in Monocultured Gnotobiotic Mice
Chriswell, M., Seifert, J., Blum, L., Bloom, M., Feser, M., Demoruelle, M. K., … Kuhn, K. (2020). Bacterial Families Lachnospiraceae/Ruminococcaceae Are Immunologically Targeted in Individuals At-risk for RA and a Specific Strain Is Arthritogenic in Monocultured Gnotobiotic Mice. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity.
Ptacek, J., Hawtin, R. E., Sun, D., Louie, B., Evensen, E., Mittleman, B. B., … Bridges, S. L. (2021). Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. PloS One, 16(1), e0244187. -
Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease
Mosel, M. R., Rebman, A. W., Carolan, H. E., Montenegro, T., Lovari, R., Schutzer, S. E., … Aucott, J. N. (2021). Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease. JOURNAL OF CLINICAL MICROBIOLOGY, 59(1). -
First-in-human phase Ib study of ATRC-101, an engineered version of a patient-derived antibody targeting a tumor-restricted ribonucleoprotein complex.
Benjamin, J. E., Higgins, N., Millward, C., Defalco, J., Manning-Bog, A., Aydin, I. T., … Greenberg, N. (2020). First-in-human phase Ib study of ATRC-101, an engineered version of a patient-derived antibody targeting a tumor-restricted ribonucleoprotein complex. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
CD52 Is Elevated on B cells of SLE Patients and Regulates B Cell Function.
Bhamidipati, K., Silberstein, J. L., Chaichian, Y., Baker, M. C., Lanz, T. V., Zia, A., … Robinson, W. H. (2020). CD52 Is Elevated on B cells of SLE Patients and Regulates B Cell Function. Frontiers in Immunology, 11, 626820. -
Predicting Lyme Disease From Patients' Peripheral Blood Mononuclear Cells Profiled With RNA-Sequencing
Clarke, D. J. B., Rebman, A. W., Bailey, A., Wojciechowicz, M. L., Jenkins, S. L., Evangelista, J. E., … Ma'ayan, A. (2021). Predicting Lyme Disease From Patients' Peripheral Blood Mononuclear Cells Profiled With RNA-Sequencing. FRONTIERS IN IMMUNOLOGY, 12, 636289. -
Associations of serum cytokines and chemokines with the risk of incident cancer in a prospective rheumatoid arthritis cohort.
England, B. R., Campany, M., Sayles, H., Roul, P., Yang, Y., Ganti, A. K., … Mikuls, T. R. (2021). Associations of serum cytokines and chemokines with the risk of incident cancer in a prospective rheumatoid arthritis cohort. International Immunopharmacology, 97, 107719. -
Neutralizing Anti-Interleukin-1 Receptor-Antagonist Autoantibodies Induce Inflammatory and Fibrotic Mediators in IgG4-Related Disease.
Jarrell, J. A., Baker, M. C., Perugino, C. A., Liu, H., Bloom, M. S., Maehara, T., … Robinson, W. H. (2021). Neutralizing Anti-Interleukin-1 Receptor-Antagonist Autoantibodies Induce Inflammatory and Fibrotic Mediators in IgG4-Related Disease. The Journal of Allergy and Clinical Immunology. -
Interleukin 4 promotes anti-inflammatory macrophages that clear cartilage debris and inhibits osteoclast development to protect against osteoarthritis.
von Kaeppler, E. P., Wang, Q., Raghu, H., Bloom, M. S., Wong, H., & Robinson, W. H. (2021). Interleukin 4 promotes anti-inflammatory macrophages that clear cartilage debris and inhibits osteoclast development to protect against osteoarthritis. Clinical Immunology (Orlando, Fla.), 108784. -
The importance of specific citrullinated clusterin and vimentin found in a multi-coloured bead-based citrulline-peptide array system in rheumatoid arthritis.
Yoshizawa, Y., Nakao, T., Tsuritani, K., Yamada, T., Watanabe, N., Chiba, A., … Miyake, S. (2021). The importance of specific citrullinated clusterin and vimentin found in a multi-coloured bead-based citrulline-peptide array system in rheumatoid arthritis. Clinical and Experimental Rheumatology. -
Pathogenic Role of Circulating Citrullinated Antigens and Anti-Cyclic Monoclonal Citrullinated Peptide Antibodies in Rheumatoid Arthritis
Won, P., Kim, Y., Jung, H., Rim, Y. A., Sohn, D. H., Robinson, W. H., … Ju, J. H. (2021). Pathogenic Role of Circulating Citrullinated Antigens and Anti-Cyclic Monoclonal Citrullinated Peptide Antibodies in Rheumatoid Arthritis. FRONTIERS IN IMMUNOLOGY, 12, 692242. -
Serologic response to Borrelia antigens varies with clinical phenotype in children and young adults with Lyme disease.
Radtke, F. A., Ramadoss, N., Garro, A. C., Bennett, J. E., Levas, M. N., Robinson, W. H., … Net, P. L. (2021). Serologic response to Borrelia antigens varies with clinical phenotype in children and young adults with Lyme disease. Journal of Clinical Microbiology, JCM0134421. -
Tendon-Derived Progenitor Cells With Multilineage Potential Are Present Within Human Patellar Tendon.
Leonardi, E. A., Xiao, M., Murray, I. R., Robinson, W. H., & Abrams, G. D. (2021). Tendon-Derived Progenitor Cells With Multilineage Potential Are Present Within Human Patellar Tendon. Orthopaedic Journal of Sports Medicine, 9(8), 23259671211023452. -
First-in-human phase 1b study of ATRC-101, a patient-derived antibody with a tumor-specific target, as monotherapy or in combination with pembrolizumab, in patients with solid tumors.
Benjamin, J. E., Higgins, N., Millward, C., DeFalco, J., Manning-Bog, A., Aydin, I. T., … Greenberg, N. M. (2021). First-in-human phase 1b study of ATRC-101, a patient-derived antibody with a tumor-specific target, as monotherapy or in combination with pembrolizumab, in patients with solid tumors. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
New-onset IgG autoantibodies in hospitalized patients with COVID-19.
Chang, S. E., Feng, A., Meng, W., Apostolidis, S. A., Mack, E., Artandi, M., … Utz, P. J. (2021). New-onset IgG autoantibodies in hospitalized patients with COVID-19. Nature Communications, 12(1), 5417. -
Effective Viral Vector SARS-CoV-2 Booster Vaccination in a Patient with Rheumatoid Arthritis after Initial Ineffective mRNA Vaccine Response.
Baker, M. C., Mallajosyula, V., Davis, M. M., Boyd, S. D., Nadeau, K. C., & Robinson, W. H. (2021). Effective Viral Vector SARS-CoV-2 Booster Vaccination in a Patient with Rheumatoid Arthritis after Initial Ineffective mRNA Vaccine Response. Arthritis & Rheumatology (Hoboken, N.J.). -
Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.
Fechtner, S., Berens, H., Bemis, E., Johnson, R. L., Guthridge, C. J., Carlson, N. E., … Holers, V. M. (2021). Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles. Arthritis & Rheumatology (Hoboken, N.J.). -
Dual IgA/IgG family plasmablast-derived mAbs from peripheral blood of individuals at risk for rheumatoid arthritis are polyreactive to autoantigens and intestinal bacteria
Chriswell, M., Bloom, M., Seifert, J. A., Feser, M., Demoruelle, M. K., Deane, K. D., … Kuhn, K. A. (2021). Dual IgA/IgG family plasmablast-derived mAbs from peripheral blood of individuals at risk for rheumatoid arthritis are polyreactive to autoantigens and intestinal bacteria. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
BNT162b2 vaccine induces divergent B cell responses to SARS-CoV-2 S1 and S2
Brewer, R. C., Ramadoss, N. S., Lahey, L. J., Jahanbani, S., Robinson, W. H., & Lanz, T. (2021). BNT162b2 vaccine induces divergent B cell responses to SARS-CoV-2 S1 and S2. NATURE IMMUNOLOGY. -
Histologic subtype of cutaneous immune-related adverse events predicts overall survival in patients receiving immune checkpoint inhibitors.
Hirotsu, K. E., Scott, M. K., Marquez, C., Tran, A. T., Rieger, K. E., Novoa, R. A., … Zaba, L. C. (2021). Histologic subtype of cutaneous immune-related adverse events predicts overall survival in patients receiving immune checkpoint inhibitors. Journal of the American Academy of Dermatology. -
Differential Changes in ACPA Fine Specificity and Gene Expression in a Randomized Trial of Abatacept and Adalimumab in Rheumatoid Arthritis.
Jabado, O., Maldonado, M. A., Schiff, M., Weinblatt, M. E., Fleischmann, R., Robinson, W. H., … Connolly, S. E. (2021). Differential Changes in ACPA Fine Specificity and Gene Expression in a Randomized Trial of Abatacept and Adalimumab in Rheumatoid Arthritis. Rheumatology and Therapy. -
Epstein-Barr virus and multiple sclerosis.
Robinson, W. H., & Steinman, L. (2022). Epstein-Barr virus and multiple sclerosis. Science (New York, N.Y.), 375(6578), 264–265. -
Clonally Expanded B Cells in Multiple Sclerosis Bind EBV EBNA1 and GlialCAM.
Lanz, T. V., Brewer, R. C., Ho, P. P., Moon, J.-S. S., Jude, K. M., Fernandez, D., … Robinson, W. H. (2022). Clonally Expanded B Cells in Multiple Sclerosis Bind EBV EBNA1 and GlialCAM. Nature. -
Antibody cross-reactivity between casein and myelin-associated glycoprotein results in central nervous system demyelination.
Chunder, R., Weier, A., Maurer, H., Luber, N., Enders, M., Luber, G., … Kuerten, S. (2022). Antibody cross-reactivity between casein and myelin-associated glycoprotein results in central nervous system demyelination. Proceedings of the National Academy of Sciences of the United States of America, 119(10), e2117034119. -
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
Li, J., Zaslavsky, M., Su, Y., Guo, J., Sikora, M. J., van Unen, V., … Davis, M. M. (2022). KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science (New York, N.Y.), eabi9591. -
Symptom Trajectories in the Transition from Pre-Rheumatoid Arthritis to Clinically-Apparent Inflammatory Arthritis
Haville, S., Seifert, J., Barzideh, S., Moss, L. K., Rao, N., Johnsen, A., … Deane, K. (2021). Symptom Trajectories in the Transition from Pre-Rheumatoid Arthritis to Clinically-Apparent Inflammatory Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Osteoarthritis Risk Is Increased in Patients with Atopic Disease
Baker, M., Sheth, K., Lu, R., Lu, D., von Kaeppler, E., Bhat, A., … Robinson, W. (2021). Osteoarthritis Risk Is Increased in Patients with Atopic Disease. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Plasmablast-derived Autoantibodies from Individuals At-risk for RA That Target RA-relevant Antigens Are Polyreactive with Arthritogenic Bacteria
Chriswell, M., Seifert, J., Bloom, M., Rims, C., Feser, M., Deane, K., … Kuhn, K. (2021). Plasmablast-derived Autoantibodies from Individuals At-risk for RA That Target RA-relevant Antigens Are Polyreactive with Arthritogenic Bacteria. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Identifying Trajectories and Endotypes in the Evolution of Pre-Rheumatoid Arthritis with Autoantibody Testing and Artificial Adaptive System Analysis
Buscema, P. M., Massini, G., Della Torre, F., Asadi-Zeydabadi, M., O'Donnell, C., Newman, F., … Deane, K. (2021). Identifying Trajectories and Endotypes in the Evolution of Pre-Rheumatoid Arthritis with Autoantibody Testing and Artificial Adaptive System Analysis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Metformin Use Reduces the Risk of Developing Osteoarthritis: A Propensity Score Matching Study
Sheth, K., Lu, D., Lu, R., Robinson, W., & Baker, M. (2021). Metformin Use Reduces the Risk of Developing Osteoarthritis: A Propensity Score Matching Study. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Autoantibodies and the Risk of Incident Cardiovascular Disease in US Veterans with Rheumatoid Arthritis
Johnson, T., Duryee, M., Hunter, C., Roul, P., Yang, Y., Sokolove, J., … England, B. (2021). Autoantibodies and the Risk of Incident Cardiovascular Disease in US Veterans with Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Single-cell Profiling of B and T Cell Repertoire and Gene Expression in the RA Synovium Reveals Tissue Specific Clonal Expansion
Meednu, N., Wagner, A., Dunlap, G., Zhang, F., Jonsson, A. H., Wei, K., … Medicines, A. (2021). Single-cell Profiling of B and T Cell Repertoire and Gene Expression in the RA Synovium Reveals Tissue Specific Clonal Expansion. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Unsupervised Clustering of Histology and Ultrasound Scores Identifies Osteoarthritis Subtypes
Konnaris, M., Bell, R., Pannellini, T., DiCarlo, E., Gibbons, J. A., Nwawka, O. K., … Mehta, B. (2021). Unsupervised Clustering of Histology and Ultrasound Scores Identifies Osteoarthritis Subtypes. ARTHRITIS & RHEUMATOLOGY. WILEY. -
New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19
Chang, S., Feng, A., Meng, W., Apostolidis, S., Mack, E., Artandi, M., … Utz, P. (2021). New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101.
Scholz, A., DeFalco, J., Leung, Y., Aydin, I. T., Czupalla, C. J., Cao, W., … Manning-Bog, A. (2022). Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101. Proceedings of the National Academy of Sciences of the United States of America, 119(19), e2123483119. -
The importance of specific citrullinated clusterin and vimentin found in a multi-coloured bead-based citrulline-peptide array system in rheumatoid arthritis
Yoshizawa, Y., Nakao, T., Tsuritani, K., Yamada, T., Watanabe, N., Chiba, A., … Miyake, S. (2022). The importance of specific citrullinated clusterin and vimentin found in a multi-coloured bead-based citrulline-peptide array system in rheumatoid arthritis. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 40(5), 936–944. -
SARS-CoV-2 infection of monocytes: balancing acts of antibodies and inflammasomes.
Brewer, R. C., Robinson, W. H., & Lanz, T. V. (2022). SARS-CoV-2 infection of monocytes: balancing acts of antibodies and inflammasomes. Signal Transduction and Targeted Therapy, 7(1), 250. -
Extracellular histones aggravate autoimmune arthritis by lytic cell death.
Jung, J., Lee, L. E., Kim, H., Kim, J. E., Jang, S. H., Roh, J. S., … Song, J. J. (2022). Extracellular histones aggravate autoimmune arthritis by lytic cell death. Frontiers in Immunology, 13, 961197. -
RNA-seq characterization of histamine-releasing mast cells as potential therapeutic target of osteoarthritis.
Zhao, X., Younis, S., Shi, H., Hu, S., Zia, A., Wong, H. H., … Robinson, W. H. (2022). RNA-seq characterization of histamine-releasing mast cells as potential therapeutic target of osteoarthritis. Clinical Immunology (Orlando, Fla.), 109117. -
Myeloablative autologous haematopoietic stem cell transplantation resets the B cell repertoire to a more naïve state in patients with systemic sclerosis.
Adamska, J. Z., Zia, A., Bloom, M. S., Crofford, L. J., Furst, D. E., Goldmuntz, E., … Robinson, W. (2022). Myeloablative autologous haematopoietic stem cell transplantation resets the B cell repertoire to a more naïve state in patients with systemic sclerosis. Annals of the Rheumatic Diseases. -
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum.
Chriswell, M. E., Lefferts, A. R., Clay, M. R., Hsu, A. R., Seifert, J., Feser, M. L., … Kuhn, K. A. (2022). Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. Science Translational Medicine, 14(668), eabn5166. -
Mechanism-driven strategies for prevention of rheumatoid arthritis.
Holers, V. M., Kuhn, K. A., Demoruelle, M. K., Norris, J. M., Firestein, G. S., James, E. A., … Deane, K. D. (2022). Mechanism-driven strategies for prevention of rheumatoid arthritis. Rheumatology & Autoimmunity, 2(3), 109–119. -
Increased macrophage phagocytic activity with TLR9 agonist conjugation of an anti- Borrelia burgdorferi monoclonal antibody.
Jahanbani, S., Hansen, P. S., Blum, L. K., Bastounis, E. E., Ramadoss, N. S., Pandrala, M., … Robinson, W. H. (2022). Increased macrophage phagocytic activity with TLR9 agonist conjugation of an anti- Borrelia burgdorferi monoclonal antibody. Clinical Immunology (Orlando, Fla.), 109180. -
Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan.
Carmona-Rivera, C., Carlucci, P. M., Moore, E., Lingampalli, N., Uchtenhagen, H., James, E., … Kaplan, M. J. (2020). Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan. Science Immunology, 5(43). -
Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting : Toronto, Canada. 14-17 April 2016.
Fotis, L., Shaikh, N., Baszis, K., French, A., Tarr, P., Grevich, S., … Co, D. O. (2016). Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting : Toronto, Canada. 14-17 April 2016. Pediatric Rheumatology Online Journal, 14 Suppl 1(Suppl 1), 41. -
Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3.
Moura, M. C., Thompson, G. E., Nelson, D. R., Fussner, L. A., Hummel, A. M., Jenne, D. E., … Specks, U. (2022). Activation of a Latent Epitope Causing Differential Binding of Anti-Neutrophil Cytoplasmic Antibodies to Proteinase 3. Arthritis & Rheumatology (Hoboken, N.J.). -
Single-Cell Characterization of the TCR Repertoire Across Tissue and Blood in Rheumatoid Arthritis
Dunlap, G., Wagner, A., Meednu, N., Jonsson, A., Zhang, F., Wei, K., … Rao, D. (2022). Single-Cell Characterization of the TCR Repertoire Across Tissue and Blood in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
CCP plus Immune Checkpoint Inhibitor Arthritis Patients Have Less ACPA Epitope Expansion Than CCP plus Rheumatoid Arthritis Patients
Ghosh, N., Rajesh, D., Kirschmann, J., Jannat-Khah, D., Chan, K. K., Goodman, S., … Bass, A. (2022). CCP plus Immune Checkpoint Inhibitor Arthritis Patients Have Less ACPA Epitope Expansion Than CCP plus Rheumatoid Arthritis Patients. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Mast Cells May Explain Sex Differences in Osteoarthritis Pain
Mehta, B., DiCarlo, E., Wang, F., Otero, M., Song, E. K., Sculco, P., … Orange, D. (2022). Mast Cells May Explain Sex Differences in Osteoarthritis Pain. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Single-cell Profiling of B Cell Repertoire and Gene Expression in the RA Synovium Reveals Tissue Specific Clonal Expansion
Wagner, A., Meednu, N., Dunlap, G., Zhang, F., Jonsson, A., Wei, K., … Anolik, J. (2022). Single-cell Profiling of B Cell Repertoire and Gene Expression in the RA Synovium Reveals Tissue Specific Clonal Expansion. ARTHRITIS & RHEUMATOLOGY. WILEY. -
An Arthritogenic Strain of Subdoligranulum Specifically Detectable in the Feces of Individuals At-risk for and with Rheumatoid Arthritis Is Bound by ACPA and Stimulates Th17 Cell Activation in Those with Rheumatoid Arthritis
Chriswell, M., Rims, C., Maerz, M., Hsu, A., Seifert, J., Feser, M., … Kuhn, K. (2022). An Arthritogenic Strain of Subdoligranulum Specifically Detectable in the Feces of Individuals At-risk for and with Rheumatoid Arthritis Is Bound by ACPA and Stimulates Th17 Cell Activation in Those with Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
An Expanded Anti-citrullinated Protein Antibody Profile Derived Using Unsupervised Machine Learning Predicts Treatment Responses to Biologic Therapies in Rheumatoid Arthritis
Aripova, N., Reed, G., England, B., Robinson, W., Pappas, D., Kremer, J., … Mikuls, T. (2022). An Expanded Anti-citrullinated Protein Antibody Profile Derived Using Unsupervised Machine Learning Predicts Treatment Responses to Biologic Therapies in Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
The Association Between Anti-Citrullinated Peptide Antibodies and Subclinical Interstitial Lung Disease in Community-Dwelling Adults: The Multi-Ethnic Study of Atherosclerosis
Lanz, J., Hughes-Austin, J., Podolanczuk, A., Kim, J., Austin, J., Robinson, W., … Bernstein, E. (2022). The Association Between Anti-Citrullinated Peptide Antibodies and Subclinical Interstitial Lung Disease in Community-Dwelling Adults: The Multi-Ethnic Study of Atherosclerosis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Clonally Expanded Cytotoxic CD8(+) T Cells Recognize Citrullinated Antigens in ACPA(+) Rheumatoid Arthritis
Younis, S., Sharpe, O., Rao, N., Carman, J., James, E., Buckner, J., … Robinson, W. (2022). Clonally Expanded Cytotoxic CD8(+) T Cells Recognize Citrullinated Antigens in ACPA(+) Rheumatoid Arthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Citrullinated Peptide-Specific ACPA Are Present in the Female Genital Tract in Premenopausal Women with and Without RA
Marcy, D., Rothfuss, H., Visser, A., Norris, J., Holers, V. M., Deane, K. D., … Demoruelle, K. (2022). Citrullinated Peptide-Specific ACPA Are Present in the Female Genital Tract in Premenopausal Women with and Without RA. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Reduction in Rheumatoid Arthritis-Associated Interstitial Lung Disease Risk in Patients Treated with Tofacitinib
Baker, M., Liu, Y., Lu, R., Lin, J., Melehani, J., & Robinson, W. (2022). Reduction in Rheumatoid Arthritis-Associated Interstitial Lung Disease Risk in Patients Treated with Tofacitinib. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Rheumatoid Arthritis Patient-derived Anti-citrullinated Protein Antibodies (ACPAs) Ameliorate Joint Inflammation in Early Collagen-antibody Induced Arthritis (CAIA)
Gomez, A., Brewer, C., Moon, J.-S., Acharya, S., Lanz, T. V., Wang, Q., … Robinson, W. (2022). Rheumatoid Arthritis Patient-derived Anti-citrullinated Protein Antibodies (ACPAs) Ameliorate Joint Inflammation in Early Collagen-antibody Induced Arthritis (CAIA). ARTHRITIS & RHEUMATOLOGY. WILEY. -
Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis.
Moon, J.-S. S., Younis, S., Ramadoss, N. S., Iyer, R., Sheth, K., Sharpe, O., … Robinson, W. H. (2023). Cytotoxic CD8+ T cells target citrullinated antigens in rheumatoid arthritis. Nature Communications, 14(1), 319. -
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum
Chriswell, M. E., Lefferts, A. R., Clay, M. R., Hsu, A. R., Seifert, J., Feser, M. L., … Kuhn, K. A. (2022). Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum. SCIENCE TRANSLATIONAL MEDICINE, 14(668). -
Roadmap for understanding mechanisms on how Epstein-Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials.
Lanz, T. V., Robinson, W. H., Ho, P. P., & Steinman, L. (2023). Roadmap for understanding mechanisms on how Epstein-Barr virus triggers multiple sclerosis and for translating these discoveries in clinical trials. Clinical & Translational Immunology, 12(2), e1438. -
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis.
Brewer, R. C., Lanz, T. V., Hale, C. R., Sepich-Poore, G. D., Martino, C., Swafford, A. D., … Orange, D. E. (2023). Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis. Science Translational Medicine, 15(684), eabq8476. -
Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study.
Lee, J. A., Mikuls, T. R., Deane, K. D., Sayles, H. R., Thiele, G. M., Edison, J. D., … Payne, J. B. (2023). Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study. Seminars in Arthritis and Rheumatism, 59, 152176. -
Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation.
Mehta, B., Goodman, S., DiCarlo, E., Jannat-Khah, D., Gibbons, J. A., Otero, M., … Orange, D. E. (2023). Machine learning identification of thresholds to discriminate osteoarthritis and rheumatoid arthritis synovial inflammation. Arthritis Research & Therapy, 25(1), 31. -
Dysfunction in parkin aggravates inflammatory bone erosion by reinforcing osteoclast activity.
Kim, E.-Y., Kim, J.-E., Kim, Y.-E., Choi, B., Sohn, D. H., Park, S.-O., … Chang, E.-J. (2023). Dysfunction in parkin aggravates inflammatory bone erosion by reinforcing osteoclast activity. Cell & Bioscience, 13(1), 48. -
Autoantibodies against citrullinated and native proteins and prediction of rheumatoid arthritis-associated interstitial lung disease: A nested case-control study.
Kronzer, V. L., Hayashi, K., Yoshida, K., Davis, J. M., McDermott, G. C., Huang, W., … Sparks, J. A. (2023). Autoantibodies against citrullinated and native proteins and prediction of rheumatoid arthritis-associated interstitial lung disease: A nested case-control study. The Lancet. Rheumatology, 5(2), e77–e87. -
FAT10 Induces cancer cell migration by stabilizing phosphorylated ABI3/NESH.
Um, H., Jeong, H., Lee, B., Kim, Y., Lee, J., Roh, J. S., … Sohn, D. H. (2023). FAT10 Induces cancer cell migration by stabilizing phosphorylated ABI3/NESH. Animal Cells and Systems, 27(1), 53–60. -
Development of Osteoarthritis in Adults With Type 2 Diabetes Treated With Metformin vs a Sulfonylurea.
Baker, M. C., Sheth, K., Liu, Y., Lu, D., Lu, R., & Robinson, W. H. (2023). Development of Osteoarthritis in Adults With Type 2 Diabetes Treated With Metformin vs a Sulfonylurea. JAMA Network Open, 6(3), e233646. -
Incidence of Interstitial Lung Disease in Patients With Rheumatoid Arthritis Treated With Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs.
Baker, M. C., Liu, Y., Lu, R., Lin, J., Melehani, J., & Robinson, W. H. (2023). Incidence of Interstitial Lung Disease in Patients With Rheumatoid Arthritis Treated With Biologic and Targeted Synthetic Disease-Modifying Antirheumatic Drugs. JAMA Network Open, 6(3), e233640. -
Increased risk of osteoarthritis in patients with atopic disease.
Baker, M. C., Sheth, K., Lu, R., Lu, D., von Kaeppler, E. P., Bhat, A., … Robinson, W. H. (2023). Increased risk of osteoarthritis in patients with atopic disease. Annals of the Rheumatic Diseases. -
Anticitrullinated peptide antibody epitope expansion and the HLA DRB1 'shared epitope' are less common in seropositive checkpoint inhibitor-induced inflammatory arthritis than in longstanding rheumatoid arthritis.
Ghosh, N., Reid, P., Aude, C. A., Kirschman, J., Goodman, S., Bykerk, V. P., … Bass, A. R. (2023). Anticitrullinated peptide antibody epitope expansion and the HLA DRB1 'shared epitope' are less common in seropositive checkpoint inhibitor-induced inflammatory arthritis than in longstanding rheumatoid arthritis. RMD Open, 9(2). -
Autoantibodies against citrullinated and native proteins and prediction of rheumatoid arthritis-associated interstitial lung disease: a nested case-control study
Kronzer, V. L., Hayashi, K., Yoshida, K., Davis, J. M., McDermott, G. C., Huang, W., … Sparks, J. A. (2023). Autoantibodies against citrullinated and native proteins and prediction of rheumatoid arthritis-associated interstitial lung disease: a nested case-control study. LANCET RHEUMATOLOGY, 5(2), E77–E87. -
Anti-citrullinated protein antibody profiles predict changes in disease activity in patients with rheumatoid arthritis initiating biologics
Aripova, N., Kremer, J. M., Pappas, D. A., Reed, G., England, B. R., Robinson, B. H., … Mikuls, T. R. (2023). Anti-citrullinated protein antibody profiles predict changes in disease activity in patients with rheumatoid arthritis initiating biologics. RHEUMATOLOGY. -
Anti-citrullinated protein antibodies with multiple specificities ameliorate collagen antibody-induced arthritis in a time-dependent manner.
Gomez, A. M., Brewer, R. C., Moon, J.-S. S., Acharya, S., Kongpachith, S., Wang, Q., … Robinson, W. H. (2023). Anti-citrullinated protein antibodies with multiple specificities ameliorate collagen antibody-induced arthritis in a time-dependent manner. Arthritis & Rheumatology (Hoboken, N.J.). -
Limited Neutralization of Omicron by Antibodies from the BNT162b2 Vaccination against SARS-CoV-2.
Lanz, T. V., Brewer, R. C., Jahanbani, S., & Robinson, W. H. (2022). Limited Neutralization of Omicron by Antibodies from the BNT162b2 Vaccination against SARS-CoV-2. Research Square. -
Serum reactivity to citrullinated protein/peptide antigens and left ventricular structure and function in the Multi-Ethnic Study of Atherosclerosis (MESA).
Hughes-Austin, J. M., Katz, R., Majka, D. S., Criqui, M. H., Robinson, W. H., Firestein, G. S., … Ix, J. H. (2023). Serum reactivity to citrullinated protein/peptide antigens and left ventricular structure and function in the Multi-Ethnic Study of Atherosclerosis (MESA). PloS One, 18(10), e0291967. -
Genetic association between atopic disease and osteoarthritis.
Baker, M. C., Robinson, W. H., & Ostrom, Q. (2023). Genetic association between atopic disease and osteoarthritis. Osteoarthritis and Cartilage. -
Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis.
James, E. A., Holers, V. M., Iyer, R., Prideaux, E. B., Rao, N. L., Rims, C., … Deane, K. D. (2023). Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis. Nature Communications, 14(1), 7637. -
A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis.
Hashemi, E., Narain Srivastava, I., Aguirre, A., Tilahan Yoseph, E., Kaushal, E., Awani, A., … Van Haren, K. P. (2023). A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis. BioRxiv : the Preprint Server for Biology. -
Does EBV infection matter for MS: EBV mediated molecular mimicry
Robinson, W. H. (2023). Does EBV infection matter for MS: EBV mediated molecular mimicry. MULTIPLE SCLEROSIS JOURNAL. SAGE PUBLICATIONS LTD. -
A candidate antibody drug for prevention of malaria.
Williams, K. L., Guerrero, S., Flores-Garcia, Y., Kim, D., Williamson, K. S., Siska, C., … Emerling, D. E. (2024). A candidate antibody drug for prevention of malaria. Nature Medicine. -
Single-cell sequencing of PBMC characterizes a distinct inflammatory monocyte subset in Lyme disease patients with Post-Treatment Lyme Disease Syndrome (PTLD)
Chen, X., Zhou, X., Ji, X., Miranda, M., Rebman, A., Kathuria, K., … Davis, M. M. (2023). Single-cell sequencing of PBMC characterizes a distinct inflammatory monocyte subset in Lyme disease patients with Post-Treatment Lyme Disease Syndrome (PTLD). JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
Clonally Expanded Cytotoxic CD8<SUP>+</SUP> T cells Target Citrullinated Antigens In ACPA<SUP>+</SUP> Rheumatoid Arthritis
Moon, J. S., Younis, S., Sharpe, O., Rao, N. L., Carman, J. A., James, E. A., … Robinson, W. H. (2023). Clonally Expanded Cytotoxic CD8+ T cells Target Citrullinated Antigens In ACPA+ Rheumatoid Arthritis. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
Rheumatoid arthritis associated with a cytotoxic cell leukemia is characterized by enhanced reactivity to citrullinated antigens
Ananth, K., Gomez-Banuelos, E., Trejo-Zambrano, I., Kirschmann, J. M., Moosic, K. B., Wang, H., … Darrah, E. (2023). Rheumatoid arthritis associated with a cytotoxic cell leukemia is characterized by enhanced reactivity to citrullinated antigens. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
Immune tolerance of citrullinated peptides.
Thomas, R., & Robinson, W. H. (2024). Immune tolerance of citrullinated peptides. Nature Reviews. Rheumatology. -
Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network.
Izmirly, P. M., Kim, M. Y., Carlucci, P. M., Preisinger, K., Cohen, B. Z., Deonaraine, K., … Furie, R. (2024). Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network. Arthritis Research & Therapy, 26(1), 54. -
Expansion of HLA-DR+ Peripheral Helper T and Naïve B cells in Anti-Citrullinated Protein Antibody-Positive Subjects At-Risk for Rheumatoid Arthritis.
Takada, H., Demoruelle, M. K., Deane, K. D., Nakamura, S., Katsumata, Y., Ikari, K., … Okamoto, Y. (2024). Expansion of HLA-DR+ Peripheral Helper T and Naïve B cells in Anti-Citrullinated Protein Antibody-Positive Subjects At-Risk for Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). -
Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis.
Wang, Q., Shao, G., Zhao, X., Wong, H. H., Chin, K., Zhao, M., … Robinson, W. H. (2024). Dysregulated fibrinolysis and plasmin activation promote the pathogenesis of osteoarthritis. JCI Insight. -
Leukotriene Inhibitors Effect on Post-Traumatic Osteoarthritis: A RealWorld Evidence Comparative Effectiveness Study
Jafarzadeh, S. R., Baker, M., Peloquin, C. E., Robinson, W. H., & Felson, D. (2023). Leukotriene Inhibitors Effect on Post-Traumatic Osteoarthritis: A RealWorld Evidence Comparative Effectiveness Study. ARTHRITIS & RHEUMATOLOGY. WILEY. -
The monocyte cell surface is a unique site of autoantigen generation in rheumatoid arthritis.
Thomas, M. A., Naik, P., Wang, H., Giles, J. T., Girgis, A. A., Kim, S.-Y. Y., … Darrah, E. (2024). The monocyte cell surface is a unique site of autoantigen generation in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America, 121(17), e2304199121. -
P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPa and facilitates macrophage evasion by Borrelia burgdorferi.
Tal, M. C., Hansen, P. S., Ogasawara, H. A., Feng, Q., Volk, R. F., Lee, B., … Zaro, B. W. (2024). P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPa and facilitates macrophage evasion by Borrelia burgdorferi. BioRxiv : the Preprint Server for Biology. -
The peculiar features, diversity and impact of citrulline-reactive autoantibodies.
Raposo, B., Klareskog, L., Robinson, W. H., Malmstrom, V., & Gronwall, C. (2024). The peculiar features, diversity and impact of citrulline-reactive autoantibodies. Nature Reviews. Rheumatology. -
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
Weinand, K., Sakaue, S., Nathan, A., Jonsson, A. H., Zhang, F., Watts, G. F. M., … Raychaudhuri, S. (2024). The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis. NATURE COMMUNICATIONS, 15(1), 4650. -
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium
Dunlap, G., Wagner, A., Meednu, N., Wang, R., Zhang, F., Ekabe, J. C., … Zhu, Z. (2024). Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium. NATURE COMMUNICATIONS, 15(1), 4991. -
Distinct mucosal endotypes as initiators and drivers of rheumatoid arthritis.
Holers, V. M., Demoruelle, K. M., Buckner, J. H., James, E. A., Firestein, G. S., Robinson, W. H., … Deane, K. D. (2024). Distinct mucosal endotypes as initiators and drivers of rheumatoid arthritis. Nature Reviews. Rheumatology. -
Cytokine and Chemokine Elevations in ACPA plus Individuals Suggest Possible Viral, Mucosal and/or Innate Responses Are Related to the Transition to Future Clinical RA
Carlson, D., Carpenter, C., Goff, S., Seifert, J., Moss, L. K., Feser, M., … Deane, K. (2023). Cytokine and Chemokine Elevations in ACPA plus Individuals Suggest Possible Viral, Mucosal and/or Innate Responses Are Related to the Transition to Future Clinical RA. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Expansion of Circulating HLA-DR<SUP>+</SUP> Peripheral Helper T Cells and CXCR5<SUP>-</SUP>CD38<SUP>+</SUP> Mature Naive B Cells in ACPA-positive Individuals At-risk for and with Classified RA
Takada, H., Demoruelle, K., Deane, K., Nakamura, S., Katsumata, Y., Ikari, K., … Okamoto, Y. (2023). Expansion of Circulating HLA-DR+ Peripheral Helper T Cells and CXCR5-CD38+ Mature Naive B Cells in ACPA-positive Individuals At-risk for and with Classified RA. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Identification of a Mast Cell-high Synovial Pathotype of Osteoarthritis
Younis, S., Bai, A., Wong, H., Love, Z., Wang, Q., & Robinson, W. (2023). Identification of a Mast Cell-high Synovial Pathotype of Osteoarthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
The Role of Plasmin and Fibrinolysis Pathways in Osteoarthritis
Wang, Q., Wong, H., Bai, A., Love, Z., Chu, C., & Robinson, W. (2023). The Role of Plasmin and Fibrinolysis Pathways in Osteoarthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Epstein-Barr virus as a potentiator of autoimmune diseases.
Robinson, W. H., Younis, S., Love, Z. Z., Steinman, L., & Lanz, T. V. (2024). Epstein-Barr virus as a potentiator of autoimmune diseases. Nature Reviews. Rheumatology. -
Cutting-edge approaches to B-cell depletion in autoimmune diseases.
Robinson, W. H., Fiorentino, D., Chung, L., Moreland, L. W., Deodhar, M., Harler, M. B., … Kunder, R. (2024). Cutting-edge approaches to B-cell depletion in autoimmune diseases. Frontiers in Immunology, 15, 1454747. -
A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets
Hashemi, E., Srivastava, I., Aguirre, A., Yoseph, E. T., & Van Haren, K. P. (2024). A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets. Annals of Neurology. -
A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets.
Hashemi, E., Srivastava, I. N., Aguirre, A., Yoseph, E. T., Kaushal, E., Awani, A., … Van Haren, K. P. (2024). A Novel Mouse Model for Cerebral Inflammatory Demyelination in X-Linked Adrenoleukodystrophy: Insights into Pathogenesis and Potential Therapeutic Targets. Annals of Neurology. -
Interferon subverts an AHR-JUN axis to promote CXCL13<SUP>+</SUP> T cells in lupus
Law, C., Wacleche, V. S., Cao, Y., Pillai, A., Sowerby, J., Hancock, B., … Rao, D. A. (2024). Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus. NATURE, 631(8022), 857-+. -
Connecting the dots: Presentation of EBV antigens on HLA class II risk alleles connects the two main risk factors of multiple sclerosis.
Lanz, T. V., & Robinson, W. H. (2024). Connecting the dots: Presentation of EBV antigens on HLA class II risk alleles connects the two main risk factors of multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America, 121(49), e2420070121. -
Oxidative stress is a shared characteristic of ME/CFS and Long COVID
Shankar, V., Wilhelmy, J., Curtis, E., Michael, B., Cervantes, L., Mallajosyula, V., … Davis, M. (2024). Oxidative stress is a shared characteristic of ME/CFS and Long COVID. JOURNAL OF IMMUNOLOGY. AMER ASSOC IMMUNOLOGISTS. -
A Seropositive RA Polygenic Risk Score Does Not Predict Progression to RA in an ACPA Positive Population
Vargas, T., Vanderlinden, L., Carry, P., Demoruelle, K., Feser, M., Kechris, K., … Norris, J. (2024). A Seropositive RA Polygenic Risk Score Does Not Predict Progression to RA in an ACPA Positive Population. ARTHRITIS & RHEUMATOLOGY. WILEY. -
ACPA Subtypes, RF Isotypes, and the Risk of Rheumatoid Arthritis-Associated Interstitial Lung Disease
Welch, J., Yang, Y., Baker, J., Wysham, K., Ascherman, D., Monach, P., … England, B. (2024). ACPA Subtypes, RF Isotypes, and the Risk of Rheumatoid Arthritis-Associated Interstitial Lung Disease. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Synovial Inflammation Is Increased in Females with Knee Osteoarthritis
Hale, C., Otero, M., Sun, D., Parides, M., Dicarlo, E., Orange, D., … Colbath, A. (2024). Synovial Inflammation Is Increased in Females with Knee Osteoarthritis. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Memory B Cell Activation and Dysregulation in Systemic Lupus Erythematosus
Younis, S., Moutusy, S., Jahanbani, S., Wu, X., Harris, M., Pandit, M., … Robinson, W. (2024). Memory B Cell Activation and Dysregulation in Systemic Lupus Erythematosus. ARTHRITIS & RHEUMATOLOGY. WILEY. -
Identification of Autoreactive Cytotoxic T Cells in ANCA-Associated Vasculitis
van Dam, L., Younis, S., Moon, J.-S., Zhang, M., Parfasar, S., Horomanski, A., … Robinson, W. (2024). Identification of Autoreactive Cytotoxic T Cells in ANCA-Associated Vasculitis. ARTHRITIS & RHEUMATOLOGY. WILEY.
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Millennium Award. Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease.
Practice Locations
Immunology and Rheumatology Clinic in Palo Alto Palo Alto, CA
Palo Alto, CAImmunology and Rheumatology Clinic in Palo Alto
900 Blake Wilbur Dr, 2nd Fl Rm W2081
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereImportant Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Referring Physicians
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Fax: 650-320-9443
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Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
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